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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:N-butylbenzenesulfonamide
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Accession:CHEBI:44237 term browser browse the term
Definition:A sulfonamide that is benzenesulfonamide substituted by a butyl group at the nitrogen atom. It has been isolated from the plant Prunus africana and has been shown to exhibit antiandrogenic activity.
Synonyms:related_synonym: Benzenesulfonic acid butyl amide;   Dellatol BBS;   Formula=C10H15NO2S;   InChI=1S/C10H15NO2S/c1-2-3-9-11-14(12,13)10-7-5-4-6-8-10/h4-8,11H,2-3,9H2,1H3;   InChIKey=IPRJXAGUEGOFGG-UHFFFAOYSA-N;   N-(n-Butyl)benzenesulfonamide;   Plastomoll BMB;   SMILES=CCCCNS(=O)(=O)c1ccccc1
 xref: CAS:3622-84-2
 xref_mesh: MESH:C065565
 xref: PDBeChem:NBB;   PMID:16783690;   PMID:17369196;   PMID:22789816;   PMID:22824510;   PMID:8512189;   Patent:CA2596618;   Patent:WO2006081994;   Reaxys:2725965


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N-butylbenzenesulfonamide term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aif1 allograft inflammatory factor 1 decreases expression EXP N-butylbenzenesulfonamide results in decreased expression of AIF1 mRNA CTD PMID:22824510 NCBI chr20:3,646,784...3,652,670
Ensembl chr20:3,646,777...3,652,668 		JBrowse link
G Esr2 estrogen receptor 2 multiple interactions ISO N-butylbenzenesulfonamide binds to and results in decreased activity of ESR2 protein CTD PMID:27633901 NCBI chr 6:94,858,438...94,909,630
Ensembl chr 6:94,809,547...94,908,919 		JBrowse link
G Nr3c1 nuclear receptor subfamily 3, group C, member 1 multiple interactions ISO N-butylbenzenesulfonamide binds to and results in decreased activity of NR3C1 protein CTD PMID:27633901 NCBI chr18:31,271,681...31,393,320
Ensembl chr18:31,271,681...31,393,375 		JBrowse link
G Pparg peroxisome proliferator-activated receptor gamma multiple interactions ISO N-butylbenzenesulfonamide binds to and results in decreased activity of PPARG protein CTD PMID:27633901 NCBI chr 4:148,423,102...148,548,471
Ensembl chr 4:148,423,194...148,548,468 		JBrowse link
Term paths to the root
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Term Annotations click to browse term
  CHEBI ontology 19751
    role 19724
      biological role 19722
        aetiopathogenetic role 19088
          neurotoxin 18010
            N-butylbenzenesulfonamide 4
Path 2
Term Annotations click to browse term
  CHEBI ontology 19751
    subatomic particle 19749
      composite particle 19749
        hadron 19749
          baryon 19749
            nucleon 19749
              atomic nucleus 19749
                atom 19749
                  main group element atom 19698
                    p-block element atom 19698
                      chalcogen 19492
                        oxygen atom 19469
                          oxygen molecular entity 19469
                            hydroxides 19267
                              oxoacid 18632
                                chalcogen oxoacid 11783
                                  sulfur oxoacid 11410
                                    sulfonic acid 7673
                                      sulfonic acid derivative 7673
                                        sulfonamide 3220
                                          N-butylbenzenesulfonamide 4
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