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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:terbutryn
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Accession:CHEBI:44156 term browser browse the term
Definition:A methylthio-1,3,5-triazine that is 2-(methylsulfanyl)-1,3,5-triazine substituted by a tert-butylamino and an ethylamino group at positions 2 and 4 respectively.
Synonyms:exact_synonym: N-(tert-butyl)-N'-ethyl-6-(methylsulfanyl)-1,3,5-triazine-2,4-diamine
 related_synonym: 2-(tert-butylamino)-4-(ethylamino)-6-(methylthio)-s-triazine;   2-(tert-butylamino)-4-(ethylamino)-6-(methylthio)triazine;   2-T-BUTYLAMINO-4-ETHYLAMINO-6-METHYLTHIO-S-TRIAZINE;   2-tert-butylamino-4-ethylamino-6-methylthio-[1,3,5]triazine;   Formula=C10H19N5S;   InChI=1S/C10H19N5S/c1-6-11-7-12-8(15-10(2,3)4)14-9(13-7)16-5/h6H2,1-5H3,(H2,11,12,13,14,15);   InChIKey=IROINLKCQGIITA-UHFFFAOYSA-N;   N(2)-tert-butyl-N(4)-ethyl-6-methylthio-1,3,5-triazine-2,4-diamine;   N-(1,1-dimethylethyl)-N'-ethyl-6-(methylthio)-1,3,5-triazine-2,4-diamine;   N-(tert-butyl)-N'-ethyl-6-(methylthio)-1,3,5-triazine-2,4-diamine;   SMILES=CCNc1nc(NC(C)(C)C)nc(SC)n1;   Terbutryne
 alt_id: CHEBI:26867;   CHEBI:44152
 xref: Beilstein:611817;   CAS:886-50-0;   DrugBank:DB08215;   KEGG:C18811
 xref_mesh: MESH:C010347
 xref: PDBeChem:MST;   PMID:11201052;   PMID:18049772;   PMID:7108146;   PPDB:624;   Pesticides:terbutryn;   Reaxys:611817;   UM-BBD_compID:c0256



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terbutryn term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cyp1a2 cytochrome P450, family 1, subfamily a, polypeptide 2 increases metabolic processing
multiple interactions
ISO CYP1A2 protein results in increased metabolism of terbutryne
POR protein promotes the reaction [CYP1A2 protein results in increased metabolism of terbutryne]
CTD PMID:8971136 NCBI chr 8:58,075,367...58,082,255
Ensembl chr 8:58,075,367...58,082,312
JBrowse link
G Nr1i2 nuclear receptor subfamily 1, group I, member 2 multiple interactions ISO terbutryne binds to and results in increased activity of NR1I2 protein CTD PMID:20024649 NCBI chr11:62,460,213...62,496,665
Ensembl chr11:62,460,213...62,496,658
JBrowse link
G Por cytochrome p450 oxidoreductase multiple interactions ISO POR protein promotes the reaction [CYP1A2 protein results in increased metabolism of terbutryne] CTD PMID:8971136 NCBI chr12:20,951,058...20,999,198
Ensembl chr12:20,951,058...20,999,245
JBrowse link

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  CHEBI ontology 19740
    role 19713
      biological role 19711
        xenobiotic 18613
          terbutryn 3
Path 2
Term Annotations click to browse term
  CHEBI ontology 19740
    subatomic particle 19738
      composite particle 19738
        hadron 19738
          baryon 19738
            nucleon 19738
              atomic nucleus 19738
                atom 19738
                  main group element atom 19686
                    main group molecular entity 19686
                      s-block molecular entity 19541
                        hydrogen molecular entity 19534
                          hydrides 19019
                            inorganic hydride 17950
                              pnictogen hydride 17935
                                nitrogen hydride 17832
                                  azane 17616
                                    ammonia 17615
                                      organic amino compound 17615
                                        polyamine 8324
                                          diamine 8252
                                            diamino-1,3,5-triazine 3829
                                              terbutryn 3
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