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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:7-methyl-7,8-dihydroguanosine-5'-diphosphate
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Accession:CHEBI:43977 term browser browse the term
Definition:A purine ribonucleoside 5'-diphosphate having 7-methyl-7,8-dihydroguanine as the nucleobase.
Synonyms:exact_synonym: 7-methyl-7,8-dihydroguanosine 5'-(trihydrogen diphosphate)
 related_synonym: 7N-METHYL-8-HYDROGUANOSINE-5'-DIPHOSPHATE;   Formula=C11H19N5O11P2;   InChI=1S/C11H19N5O11P2/c1-15-3-16(8-5(15)9(19)14-11(12)13-8)10-7(18)6(17)4(26-10)2-25-29(23,24)27-28(20,21)22/h4,6-7,10,17-18H,2-3H2,1H3,(H,23,24)(H2,20,21,22)(H3,12,13,14,19)/t4-,6-,7-,10-/m1/s1;   InChIKey=QQODJOAVWUWVHJ-KQYNXXCUSA-N;   SMILES=CN1CN([C@@H]2O[C@H](COP(O)(=O)OP(O)(O)=O)[C@@H](O)[C@H]2O)c2nc(N)[nH]c(=O)c12
 xref: CAS:104809-16-7
 xref_mesh: MESH:C111106
 xref: Reaxys:1198218
 cyclic_relationship: is_conjugate_acid_of CHEBI:63814


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7-methyl-7,8-dihydroguanosine-5'-diphosphate term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Eif4e eukaryotic translation initiation factor 4E affects binding
multiple interactions
ISO 7-methylguanosine 5'-diphosphate analog binds to EIF4E protein
7-methylguanosine triphosphate inhibits the reaction [7-methylguanosine 5'-diphosphate analog binds to EIF4E protein]; 7-methylguanosine-5'-monophosphate inhibits the reaction [7-methylguanosine 5'-diphosphate analog binds to EIF4E protein]; Guanosine analog inhibits the reaction [7-methylguanosine 5'-diphosphate analog binds to EIF4E protein]; Quinolones inhibits the reaction [7-methylguanosine 5'-diphosphate analog binds to EIF4E protein]; Sulfonamides inhibits the reaction [7-methylguanosine 5'-diphosphate analog binds to EIF4E protein]
CTD PMID:27592390 NCBI chr 2:243,819,616...243,853,987
Ensembl chr 2:243,820,661...243,852,631
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Term Annotations click to browse term
  CHEBI ontology 19883
    role 19833
      application 19505
        solvent 16574
          phosphoric acid 7943
            phosphoric acid derivative 7624
              organic phosphate 7623
                nucleoside phosphate 1703
                  nucleoside diphosphate 107
                    ribonucleoside diphosphate 107
                      purine ribonucleoside diphosphate 92
                        purine ribonucleoside 5'-diphosphate 92
                          7-methyl-7,8-dihydroguanosine-5'-diphosphate 1
Path 2
Term Annotations click to browse term
  CHEBI ontology 19883
    subatomic particle 19881
      composite particle 19881
        hadron 19881
          baryon 19881
            nucleon 19881
              atomic nucleus 19881
                atom 19881
                  main group element atom 19771
                    p-block element atom 19771
                      chalcogen 19464
                        oxygen atom 19425
                          oxygen molecular entity 19425
                            hydroxides 19147
                              oxoacid 18286
                                pnictogen oxoacid 10306
                                  phosphorus oxoacid 9226
                                    phosphoric acids 7943
                                      phosphoric acid 7943
                                        phosphoric acid derivative 7624
                                          phosphate 7624
                                            organic phosphate 7623
                                              carbohydrate phosphate 1709
                                                phospho sugar 1633
                                                  aldose phosphate 1631
                                                    aldopentose phosphate 1625
                                                      ribose phosphate 1620
                                                        ribonucleotide 1581
                                                          ribonucleoside 5'-phosphate 596
                                                            ribonucleoside 5'-diphosphate 107
                                                              purine ribonucleoside 5'-diphosphate 92
                                                                7-methyl-7,8-dihydroguanosine-5'-diphosphate 1
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