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Accession:CHEBI:43968 term browser browse the term
Definition:A carbapenemcarboxylic acid in which the azetidine and pyrroline rings carry 1-hydroxymethyl and in which the azetidine and pyrroline rings carry 1-hydroxymethyl and 5-(dimethylcarbamoyl)pyrrolidin-3-ylthio substituents respectively.
Synonyms:exact_synonym: (6S)-2-{[(3S,5S)-5-(dimethylcarbamoyl)pyrrolidin-3-yl]sulfanyl}-6-[(1R)-1-hydroxyethyl]-1beta-methyl-2,3-didehydro-1-carbapenam-3-carboxylic acid
 related_synonym: (1R,5S,6S)-2-[(3S,5S)-5-DIMETHYLAMINOCARBONYLPYRROLIDIN-3-YLTHIO]-6-[(R)-1-HYDROXYETHYL]-1-METHYLCARBAPEN-2-EM-3-CARBOXYLIC ACID;   (4R,5S,6S)-3-{[(3S,5S)-5-(dimethylcarbamoyl)pyrrolidin-3-yl]thio}-6-[(1R)-1-hydroxyethyl]-4-methyl-7-oxo-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid;   Antibiotic SM 7338;   Formula=C17H25N3O5S;   InChI=1S/C17H25N3O5S/c1-7-12-11(8(2)21)16(23)20(12)13(17(24)25)14(7)26-9-5-10(18-6-9)15(22)19(3)4/h7-12,18,21H,5-6H2,1-4H3,(H,24,25)/t7-,8-,9+,10+,11-,12-/m1/s1;   InChIKey=DMJNNHOOLUXYBV-PQTSNVLCSA-N;   MEPM;   SMILES=[H][C@]12[C@@H](C)C(S[C@@H]3CN[C@@H](C3)C(=O)N(C)C)=C(N1C(=O)[C@]2([H])[C@@H](C)O)C(O)=O;   meropenem anhydrous;   meropenemum
 xref: Beilstein:6826115 "Beilstein";   CAS:96036-03-2 "ChemIDplus";   DrugBank:DB00760;   Drug_Central:1709 "DrugCentral";   LINCS:LSM-5208
 xref_mesh: MESH:C059500
 xref: PDBeChem:MER;   PMID:10776838 "Europe PMC";   PMID:11069213 "Europe PMC";   PMID:18611786 "Europe PMC";   PMID:18645546 "Europe PMC";   PMID:28343819 "Europe PMC";   PMID:28371721 "Europe PMC";   PMID:28583381 "Europe PMC";   PMID:28669829 "Europe PMC";   PMID:28677407 "Europe PMC";   PMID:7588092 "Europe PMC";   Patent:EP126587;   Patent:US4943569;   Wikipedia:Meropenem

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meropenem term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G RT1-DOb RT1 class II, locus DOb JBrowse link 20 4,020,273 4,026,398 RGD:6480464

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19679
    role 19623
      biological role 19621
        antimicrobial agent 17158
          antibacterial agent 12907
            meropenem 1
              meropenem trihydrate 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 19679
    subatomic particle 19675
      composite particle 19675
        hadron 19675
          baryon 19675
            nucleon 19675
              atomic nucleus 19675
                atom 19675
                  main group element atom 19555
                    p-block element atom 19555
                      carbon group element atom 19438
                        carbon atom 19430
                          organic molecular entity 19430
                            organic group 18351
                              organic divalent group 18340
                                organodiyl group 18340
                                  carbonyl group 18225
                                    carbonyl compound 18225
                                      carboxylic acid 17930
                                        carboacyl group 16948
                                          univalent carboacyl group 16948
                                            carbamoyl group 16627
                                              carboxamide 16627
                                                lactam 2856
                                                  beta-lactam 710
                                                    beta-lactam antibiotic 698
                                                      carbapenems 21
                                                        carbapenemcarboxylic acid 1
                                                          meropenem 1
                                                            meropenem trihydrate 0
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.