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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:obeticholic acid
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Accession:CHEBI:43602 term browser browse the term
Definition:A dihydroxy-5beta-cholanic acid that is chenodeoxycholic acid carrying an additional ethyl substituent at the 6alpha-position. A semi-synthetic bile acid which acts as a farnesoid X receptor agonist and is used for treatment of primary biliary cholangitis.
Synonyms:exact_synonym: 6alpha-ethyl-3alpha,7alpha-dihydroxy-5beta-cholan-24-oic acid
 related_synonym: (3alpha,5beta,6alpha,7alpha)-6-ethyl-3,7-dihydroxycholan-24-oic acid;   6-ECDCA;   6-Ethyl-CDCA;   6-Ethylchenodeoxycholic acid;   6alpha-Ethyl-chenodeoxycholic acid;   6alpha-ethylchenodeoxycholic acid;   Formula=C26H44O4;   INT 747;   INT747;   InChI=1S/C26H44O4/c1-5-17-21-14-16(27)10-12-26(21,4)20-11-13-25(3)18(15(2)6-9-22(28)29)7-8-19(25)23(20)24(17)30/h15-21,23-24,27,30H,5-14H2,1-4H3,(H,28,29)/t15-,16-,17-,18-,19+,20+,21+,23+,24-,25-,26-/m1/s1;   InChIKey=ZXERDUOLZKYMJM-ZWECCWDJSA-N;   Ocaliva;   SMILES=C1[C@@]2([C@]3(CC[C@]4([C@]([C@@]3([C@@H]([C@@H]([C@@]2(C[C@@H](C1)O)[H])CC)O)[H])(CC[C@@]4([C@@H](CCC(O)=O)C)[H])[H])C)[H])C
 alt_id: CHEBI:132971;   CHEBI:41467;   CHEBI:43599;   MESH:C464660
 xref: CAS:459789-99-2;   Drug_Central:5155;   KEGG:C15636;   KEGG:D09360
 xref_mesh: MESH:C464660
 xref: PDBeChem:CHC;   PMID:22406511;   PMID:23593273;   PMID:24382005;   PMID:24623154;   PMID:25329562;   PMID:25421586;   PMID:25468160;   PMID:25500425;   PMID:25592258;   PMID:25726736;   PMID:25753820;   PMID:25864227;   PMID:26136168;   PMID:26169860;   PMID:26169861;   PMID:26169862;   PMID:26549695;   PMID:26723896;   PMID:26811456;   PMID:26812075;   PMID:27109453;   PMID:27406083;   PMID:27425465;   PMID:27468093;   PMID:27475255;   Reaxys:9238543;   Wikipedia:Obeticholic_acid


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obeticholic acid term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G R A2m alpha-2-macroglobulin decreases expression ISO obeticholic acid results in decreased expression of A2M mRNA CTD PMID:27939613 NCBI chr 4:154,309,426...154,359,138
Ensembl chr 4:154,309,426...154,359,137
Ensembl chr 4:154,309,426...154,359,137
JBrowse link
G M A2m alpha-2-macroglobulin decreases expression ISO obeticholic acid results in decreased expression of A2M mRNA CTD PMID:27939613 NCBI chr 6:121,636,165...121,679,238
Ensembl chr 6:121,635,376...121,679,227
JBrowse link
G H A2M alpha-2-macroglobulin decreases expression EXP obeticholic acid results in decreased expression of A2M mRNA CTD PMID:27939613 NCBI chr12:9,067,708...9,116,229
Ensembl chr12:9,067,664...9,116,229
JBrowse link
G R Abca1 ATP binding cassette subfamily A member 1 decreases expression ISO obeticholic acid results in decreased expression of ABCA1 mRNA CTD PMID:27939613 NCBI chr 5:69,857,717...69,983,042
Ensembl chr 5:69,857,771...69,983,015
JBrowse link
G M Abca1 ATP-binding cassette, sub-family A (ABC1), member 1 decreases expression ISO obeticholic acid results in decreased expression of ABCA1 mRNA CTD PMID:27939613 NCBI chr 4:53,030,789...53,159,988
Ensembl chr 4:53,030,787...53,159,895
JBrowse link
G H ABCA1 ATP binding cassette subfamily A member 1 decreases expression EXP obeticholic acid results in decreased expression of ABCA1 mRNA CTD PMID:27939613 NCBI chr 9:104,781,006...104,928,232
Ensembl chr 9:104,781,006...104,928,155
JBrowse link
G R Abcb11 ATP binding cassette subfamily B member 11 multiple interactions
increases expression
ISO
EXP
obeticholic acid promotes the reaction [PRMT1 protein binds to ABCB11 promoter]
Obeticholic acid inhibits the reaction [ethanol decreases expression of Abcb11 protein in liver]
obeticholic acid promotes the reaction [1-Naphthylisothiocyanate results in increased expression of ABCB11 mRNA]; obeticholic acid promotes the reaction [1-Naphthylisothiocyanate results in increased expression of ABCB11 protein]
obeticholic acid results in increased expression of ABCB11 mRNA
obeticholic acid inhibits the reaction [Isoniazid results in decreased expression of ABCB11 mRNA]; obeticholic acid inhibits the reaction [Pyrazinamide results in decreased expression of ABCB11 mRNA]
CTD PMID:15644430 PMID:15911693 PMID:27255380 PMID:27939613 PMID:29660435 PMID:32673658, PMID:27939985 RGD:15036816 NCBI chr 3:55,480,024...55,587,946
Ensembl chr 3:55,480,024...55,587,946
JBrowse link
G M Abcb11 ATP-binding cassette, sub-family B (MDR/TAP), member 11 multiple interactions
increases expression
ISO
EXP
obeticholic acid promotes the reaction [PRMT1 protein binds to ABCB11 promoter]
Obeticholic acid inhibits the reaction [ethanol decreases expression of Abcb11 protein in liver]
obeticholic acid promotes the reaction [1-Naphthylisothiocyanate results in increased expression of ABCB11 mRNA]; obeticholic acid promotes the reaction [1-Naphthylisothiocyanate results in increased expression of ABCB11 protein]
obeticholic acid results in increased expression of ABCB11 mRNA
obeticholic acid inhibits the reaction [Isoniazid results in decreased expression of ABCB11 mRNA]; obeticholic acid inhibits the reaction [Pyrazinamide results in decreased expression of ABCB11 mRNA]
CTD PMID:15644430 PMID:15911693 PMID:27255380 PMID:27939613 PMID:29660435 PMID:32673658, PMID:27939985 RGD:15036816 NCBI chr 2:69,238,282...69,342,616
Ensembl chr 2:69,238,282...69,342,616
JBrowse link
G H ABCB11 ATP binding cassette subfamily B member 11 multiple interactions
increases expression
EXP
ISO
obeticholic acid promotes the reaction [PRMT1 protein binds to ABCB11 promoter]
Obeticholic acid inhibits the reaction [ethanol decreases expression of Abcb11 protein in liver]
obeticholic acid promotes the reaction [1-Naphthylisothiocyanate results in increased expression of ABCB11 mRNA]; obeticholic acid promotes the reaction [1-Naphthylisothiocyanate results in increased expression of ABCB11 protein]
obeticholic acid results in increased expression of ABCB11 mRNA
obeticholic acid inhibits the reaction [Isoniazid results in decreased expression of ABCB11 mRNA]; obeticholic acid inhibits the reaction [Pyrazinamide results in decreased expression of ABCB11 mRNA]
CTD PMID:15644430 PMID:15911693 PMID:27255380 PMID:27939613 PMID:29660435 PMID:32673658, PMID:27939985 RGD:15036816 NCBI chr 2:168,915,468...169,031,396
Ensembl chr 2:168,915,498...169,031,324
JBrowse link
G R Abcb4 ATP binding cassette subfamily B member 4 multiple interactions
increases expression
EXP
ISO
obeticholic acid inhibits the reaction [Pyrazinamide results in decreased expression of ABCB4 mRNA]
obeticholic acid results in increased expression of ABCB4 mRNA
CTD PMID:15644430 PMID:27255380 PMID:27939613 NCBI chr 4:22,133,984...22,192,687
Ensembl chr 4:22,133,521...22,425,515
JBrowse link
G M Abcb4 ATP-binding cassette, sub-family B (MDR/TAP), member 4 multiple interactions
increases expression
ISO obeticholic acid inhibits the reaction [Pyrazinamide results in decreased expression of ABCB4 mRNA]
obeticholic acid results in increased expression of ABCB4 mRNA
CTD PMID:15644430 PMID:27255380 PMID:27939613 NCBI chr 5:8,893,614...8,959,226
Ensembl chr 5:8,893,717...8,959,231
JBrowse link
G H ABCB4 ATP binding cassette subfamily B member 4 multiple interactions
increases expression
ISO
EXP
obeticholic acid inhibits the reaction [Pyrazinamide results in decreased expression of ABCB4 mRNA]
obeticholic acid results in increased expression of ABCB4 mRNA
CTD PMID:15644430 PMID:27255380 PMID:27939613 NCBI chr 7:87,398,988...87,476,722
Ensembl chr 7:87,401,697...87,480,435
Ensembl chr 7:87,401,697...87,480,435
JBrowse link
G R Abcc2 ATP binding cassette subfamily C member 2 multiple interactions
increases expression
EXP
ISO
obeticholic acid inhibits the reaction [Pyrazinamide results in decreased expression of ABCC2 mRNA]
NR1H4 promotes the reaction [obeticholic acid promotes the reaction [1-Naphthylisothiocyanate results in increased expression of ABCC2 mRNA]]; obeticholic acid promotes the reaction [1-Naphthylisothiocyanate results in increased expression of ABCC2 mRNA]; obeticholic acid promotes the reaction [1-Naphthylisothiocyanate results in increased expression of ABCC2 protein]
obeticholic acid results in increased expression of ABCC2 mRNA
CTD PMID:15644430 PMID:27255380 PMID:29660435 NCBI chr 1:263,554,426...263,612,556
Ensembl chr 1:263,554,453...263,613,252
JBrowse link
G M Abcc2 ATP-binding cassette, sub-family C (CFTR/MRP), member 2 multiple interactions
increases expression
ISO
EXP
obeticholic acid inhibits the reaction [Pyrazinamide results in decreased expression of ABCC2 mRNA]
NR1H4 promotes the reaction [obeticholic acid promotes the reaction [1-Naphthylisothiocyanate results in increased expression of ABCC2 mRNA]]; obeticholic acid promotes the reaction [1-Naphthylisothiocyanate results in increased expression of ABCC2 mRNA]; obeticholic acid promotes the reaction [1-Naphthylisothiocyanate results in increased expression of ABCC2 protein]
obeticholic acid results in increased expression of ABCC2 mRNA
CTD PMID:15644430 PMID:27255380 PMID:29660435 NCBI chr19:43,782,308...43,838,332
Ensembl chr19:43,782,192...43,840,740
JBrowse link
G H ABCC2 ATP binding cassette subfamily C member 2 multiple interactions
increases expression
ISO obeticholic acid inhibits the reaction [Pyrazinamide results in decreased expression of ABCC2 mRNA]
NR1H4 promotes the reaction [obeticholic acid promotes the reaction [1-Naphthylisothiocyanate results in increased expression of ABCC2 mRNA]]; obeticholic acid promotes the reaction [1-Naphthylisothiocyanate results in increased expression of ABCC2 mRNA]; obeticholic acid promotes the reaction [1-Naphthylisothiocyanate results in increased expression of ABCC2 protein]
obeticholic acid results in increased expression of ABCC2 mRNA
CTD PMID:15644430 PMID:27255380 PMID:29660435 NCBI chr10:99,782,602...99,853,741
Ensembl chr10:99,782,640...99,852,594
JBrowse link
G R Abcc3 ATP binding cassette subfamily C member 3 multiple interactions EXP obeticholic acid inhibits the reaction [Isoniazid results in decreased expression of ABCC3 mRNA] CTD PMID:32673658 NCBI chr10:82,047,308...82,116,928
Ensembl chr10:82,047,863...82,117,109
JBrowse link
G M Abcc3 ATP-binding cassette, sub-family C (CFTR/MRP), member 3 multiple interactions ISO obeticholic acid inhibits the reaction [Isoniazid results in decreased expression of ABCC3 mRNA] CTD PMID:32673658 NCBI chr11:94,343,295...94,393,017
Ensembl chr11:94,343,295...94,392,997
JBrowse link
G H ABCC3 ATP binding cassette subfamily C member 3 multiple interactions ISO obeticholic acid inhibits the reaction [Isoniazid results in decreased expression of ABCC3 mRNA] CTD PMID:32673658 NCBI chr17:50,634,881...50,692,253
Ensembl chr17:50,634,777...50,692,253
JBrowse link
G R Abcg1 ATP binding cassette subfamily G member 1 decreases expression ISO obeticholic acid results in decreased expression of ABCG1 mRNA CTD PMID:27939613 NCBI chr20:9,743,269...9,842,735
Ensembl chr20:9,743,269...9,840,489
JBrowse link
G M Abcg1 ATP binding cassette subfamily G member 1 decreases expression ISO obeticholic acid results in decreased expression of ABCG1 mRNA CTD PMID:27939613 NCBI chr17:31,057,694...31,117,984
Ensembl chr17:31,057,675...31,117,988
JBrowse link
G H ABCG1 ATP binding cassette subfamily G member 1 decreases expression EXP obeticholic acid results in decreased expression of ABCG1 mRNA CTD PMID:27939613 NCBI chr21:42,199,689...42,304,387
Ensembl chr21:42,199,689...42,297,244
JBrowse link
G H ACAA1 acetyl-CoA acyltransferase 1 increases expression EXP obeticholic acid results in increased expression of ACAA1 mRNA CTD PMID:27939613 NCBI chr 3:38,122,710...38,137,127
Ensembl chr 3:38,103,129...38,137,242
JBrowse link
G R Acaa1a acetyl-CoA acyltransferase 1A increases expression ISO obeticholic acid results in increased expression of ACAA1 mRNA CTD PMID:27939613 NCBI chr 8:128,027,880...128,036,471
Ensembl chr 8:128,027,958...128,036,236
JBrowse link
G M Acaa1b acetyl-Coenzyme A acyltransferase 1B increases expression ISO obeticholic acid results in increased expression of ACAA1 mRNA CTD PMID:27939613 NCBI chr 9:119,148,043...119,157,093
Ensembl chr 9:119,148,023...119,157,093
JBrowse link
G R Acaa2 acetyl-CoA acyltransferase 2 increases expression ISO obeticholic acid results in increased expression of ACAA2 mRNA CTD PMID:27939613 NCBI chr18:70,733,872...70,762,395
Ensembl chr18:70,733,872...70,762,395
JBrowse link
G M Acaa2 acetyl-Coenzyme A acyltransferase 2 (mitochondrial 3-oxoacyl-Coenzyme A thiolase) increases expression ISO obeticholic acid results in increased expression of ACAA2 mRNA CTD PMID:27939613 NCBI chr18:74,779,212...74,806,207
Ensembl chr18:74,779,197...74,806,208
JBrowse link
G H ACAA2 acetyl-CoA acyltransferase 2 increases expression EXP obeticholic acid results in increased expression of ACAA2 mRNA CTD PMID:27939613 NCBI chr18:49,782,164...49,813,533
Ensembl chr18:49,782,164...49,813,953
JBrowse link
G R Acaca acetyl-CoA carboxylase alpha decreases expression ISO obeticholic acid results in decreased expression of ACACA mRNA CTD PMID:27939613 NCBI chr10:71,519,392...71,719,910
Ensembl chr10:71,536,533...71,719,910
JBrowse link
G M Acaca acetyl-Coenzyme A carboxylase alpha decreases expression ISO obeticholic acid results in decreased expression of ACACA mRNA CTD PMID:27939613 NCBI chr11:84,129,635...84,401,651
Ensembl chr11:84,129,672...84,401,651
JBrowse link
G H ACACA acetyl-CoA carboxylase alpha decreases expression EXP obeticholic acid results in decreased expression of ACACA mRNA CTD PMID:27939613 NCBI chr17:37,084,992...37,406,836
Ensembl chr17:37,084,992...37,406,836
JBrowse link
G R Acot9 acyl-CoA thioesterase 9 increases expression ISO obeticholic acid results in increased expression of ACOT9 mRNA CTD PMID:27939613 NCBI chr  X:43,543,069...43,592,200
Ensembl chr  X:43,543,070...43,592,200
JBrowse link
G M Acot9 acyl-CoA thioesterase 9 increases expression ISO obeticholic acid results in increased expression of ACOT9 mRNA CTD PMID:27939613 NCBI chr  X:155,262,443...155,297,654
Ensembl chr  X:155,262,443...155,297,654
JBrowse link
G H ACOT9 acyl-CoA thioesterase 9 increases expression EXP obeticholic acid results in increased expression of ACOT9 mRNA CTD PMID:27939613 NCBI chr  X:23,701,055...23,743,276
Ensembl chr  X:23,701,055...23,766,475
JBrowse link
G R Acox1 acyl-CoA oxidase 1 increases expression ISO obeticholic acid results in increased expression of ACOX1 mRNA CTD PMID:26655953 PMID:27939613 NCBI chr10:104,724,534...104,748,003
Ensembl chr10:104,722,958...104,748,050
JBrowse link
G M Acox1 acyl-Coenzyme A oxidase 1, palmitoyl increases expression EXP
ISO
obeticholic acid results in increased expression of ACOX1 mRNA CTD PMID:26655953 PMID:27939613 NCBI chr11:116,171,883...116,199,045
Ensembl chr11:116,171,888...116,199,045
JBrowse link
G H ACOX1 acyl-CoA oxidase 1 increases expression ISO
EXP
obeticholic acid results in increased expression of ACOX1 mRNA CTD PMID:26655953 PMID:27939613 NCBI chr17:75,941,507...75,979,199
Ensembl chr17:75,941,507...75,979,177
JBrowse link
G R Acox2 acyl-CoA oxidase 2 increases expression ISO obeticholic acid results in increased expression of ACOX2 mRNA CTD PMID:27939613 NCBI chr15:18,449,304...18,481,472
Ensembl chr15:18,451,144...18,481,470
JBrowse link
G M Acox2 acyl-Coenzyme A oxidase 2, branched chain increases expression ISO obeticholic acid results in increased expression of ACOX2 mRNA CTD PMID:27939613 NCBI chr14:8,225,511...8,259,019
Ensembl chr14:8,225,511...8,259,353
JBrowse link
G H ACOX2 acyl-CoA oxidase 2 increases expression EXP obeticholic acid results in increased expression of ACOX2 mRNA CTD PMID:27939613 NCBI chr 3:58,505,136...58,537,196
Ensembl chr 3:58,505,136...58,537,283
JBrowse link
G R Acox3 acyl-CoA oxidase 3, pristanoyl increases expression ISO obeticholic acid results in increased expression of ACOX3 mRNA CTD PMID:27939613 NCBI chr14:80,313,202...80,358,115
Ensembl chr14:80,314,431...80,355,420
JBrowse link
G M Acox3 acyl-Coenzyme A oxidase 3, pristanoyl increases expression ISO obeticholic acid results in increased expression of ACOX3 mRNA CTD PMID:27939613 NCBI chr 5:35,582,981...35,614,208
Ensembl chr 5:35,583,040...35,615,352
JBrowse link
G H ACOX3 acyl-CoA oxidase 3, pristanoyl increases expression EXP obeticholic acid results in increased expression of ACOX3 mRNA CTD PMID:27939613 NCBI chr 4:8,366,263...8,440,723
Ensembl chr 4:8,366,282...8,440,723
JBrowse link
G R Acsl1 acyl-CoA synthetase long-chain family member 1 decreases expression ISO obeticholic acid results in decreased expression of ACSL1 mRNA CTD PMID:27939613 NCBI chr16:48,937,456...49,003,898
Ensembl chr16:48,937,456...49,003,246
JBrowse link
G M Acsl1 acyl-CoA synthetase long-chain family member 1 decreases expression ISO obeticholic acid results in decreased expression of ACSL1 mRNA CTD PMID:27939613 NCBI chr 8:46,471,037...46,536,051
Ensembl chr 8:46,471,037...46,536,051
JBrowse link
G H ACSL1 acyl-CoA synthetase long chain family member 1 decreases expression EXP obeticholic acid results in decreased expression of ACSL1 mRNA CTD PMID:27939613 NCBI chr 4:184,755,595...184,826,593
Ensembl chr 4:184,755,595...184,826,818
JBrowse link
G R Acsl4 acyl-CoA synthetase long-chain family member 4 increases expression ISO obeticholic acid results in increased expression of ACSL4 mRNA CTD PMID:27939613 NCBI chr  X:113,596,247...113,660,024
Ensembl chr  X:113,596,239...113,659,944
JBrowse link
G M Acsl4 acyl-CoA synthetase long-chain family member 4 increases expression ISO obeticholic acid results in increased expression of ACSL4 mRNA CTD PMID:27939613 NCBI chr  X:142,317,993...142,390,802
Ensembl chr  X:142,317,993...142,390,535
JBrowse link
G H ACSL4 acyl-CoA synthetase long chain family member 4 increases expression EXP obeticholic acid results in increased expression of ACSL4 mRNA CTD PMID:27939613 NCBI chr  X:109,641,335...109,733,325
Ensembl chr  X:109,624,244...109,733,403
JBrowse link
G R Acsl5 acyl-CoA synthetase long-chain family member 5 increases expression ISO obeticholic acid results in increased expression of ACSL5 mRNA CTD PMID:27939613 NCBI chr 1:276,240,703...276,290,012
Ensembl chr 1:276,240,703...276,290,008
JBrowse link
G M Acsl5 acyl-CoA synthetase long-chain family member 5 increases expression ISO obeticholic acid results in increased expression of ACSL5 mRNA CTD PMID:27939613 NCBI chr19:55,251,861...55,296,628
Ensembl chr19:55,251,938...55,297,720
JBrowse link
G H ACSL5 acyl-CoA synthetase long chain family member 5 increases expression EXP obeticholic acid results in increased expression of ACSL5 mRNA CTD PMID:27939613 NCBI chr10:112,374,116...112,428,376
Ensembl chr10:112,374,018...112,428,380
JBrowse link
G R Acsl6 acyl-CoA synthetase long-chain family member 6 increases expression ISO obeticholic acid results in increased expression of ACSL6 mRNA CTD PMID:27939613 NCBI chr10:39,654,771...39,717,592
Ensembl chr10:39,655,455...39,719,312
JBrowse link
G M Acsl6 acyl-CoA synthetase long-chain family member 6 increases expression ISO obeticholic acid results in increased expression of ACSL6 mRNA CTD PMID:27939613 NCBI chr11:54,303,805...54,364,756
Ensembl chr11:54,303,798...54,364,756
JBrowse link
G H ACSL6 acyl-CoA synthetase long chain family member 6 increases expression EXP obeticholic acid results in increased expression of ACSL6 mRNA CTD PMID:27939613 NCBI chr 5:131,949,973...132,012,068
Ensembl chr 5:131,949,973...132,012,243
JBrowse link
G R Adamtsl2 ADAMTS-like 2 decreases expression ISO obeticholic acid results in decreased expression of ADAMTSL2 mRNA CTD PMID:27939613 NCBI chr 3:5,624,473...5,654,890
Ensembl chr 3:5,624,506...5,654,910
JBrowse link
G M Adamtsl2 ADAMTS-like 2 decreases expression ISO obeticholic acid results in decreased expression of ADAMTSL2 mRNA CTD PMID:27939613 NCBI chr 2:27,079,336...27,108,981
Ensembl chr 2:27,079,379...27,108,981
JBrowse link
G H ADAMTSL2 ADAMTS like 2 decreases expression EXP obeticholic acid results in decreased expression of ADAMTSL2 mRNA CTD PMID:27939613 NCBI chr 9:133,532,164...133,575,519
Ensembl chr 9:133,532,164...133,575,519
JBrowse link
G R Adcy1 adenylate cyclase 1 increases expression ISO obeticholic acid results in increased expression of ADCY1 mRNA CTD PMID:27939613 NCBI chr14:87,311,970...87,429,880
Ensembl chr14:87,312,203...87,421,659
JBrowse link
G M Adcy1 adenylate cyclase 1 increases expression ISO obeticholic acid results in increased expression of ADCY1 mRNA CTD PMID:27939613 NCBI chr11:7,063,433...7,178,506
Ensembl chr11:7,063,489...7,178,506
JBrowse link
G H ADCY1 adenylate cyclase 1 increases expression EXP obeticholic acid results in increased expression of ADCY1 mRNA CTD PMID:27939613 NCBI chr 7:45,574,140...45,723,116
Ensembl chr 7:45,574,140...45,723,116
JBrowse link
G R Adh1 alcohol dehydrogenase 1 (class I) decreases expression ISO obeticholic acid results in decreased expression of ADH1C mRNA CTD PMID:27939613 NCBI chr 2:243,550,655...243,562,243
Ensembl chr 2:243,550,627...243,687,857
JBrowse link
G M Adh1 alcohol dehydrogenase 1 (class I) decreases expression ISO obeticholic acid results in decreased expression of ADH1C mRNA CTD PMID:27939613 NCBI chr 3:138,277,585...138,290,698
Ensembl chr 3:138,260,991...138,290,698
JBrowse link
G H ADH1C alcohol dehydrogenase 1C (class I), gamma polypeptide decreases expression EXP obeticholic acid results in decreased expression of ADH1C mRNA CTD PMID:27939613 NCBI chr 4:99,336,497...99,352,746
Ensembl chr 4:99,336,497...99,352,746
JBrowse link
G R Agpat2 1-acylglycerol-3-phosphate O-acyltransferase 2 decreases expression ISO obeticholic acid results in decreased expression of AGPAT2 mRNA CTD PMID:27939613 NCBI chr 3:4,044,741...4,055,384
Ensembl chr 3:4,044,542...4,055,806
JBrowse link
G M Agpat2 1-acylglycerol-3-phosphate O-acyltransferase 2 (lysophosphatidic acid acyltransferase, beta) decreases expression ISO obeticholic acid results in decreased expression of AGPAT2 mRNA CTD PMID:27939613 NCBI chr 2:26,593,057...26,604,417
Ensembl chr 2:26,593,057...26,604,417
JBrowse link
G H AGPAT2 1-acylglycerol-3-phosphate O-acyltransferase 2 decreases expression EXP obeticholic acid results in decreased expression of AGPAT2 mRNA CTD PMID:27939613 NCBI chr 9:136,673,143...136,687,457
Ensembl chr 9:136,673,143...136,687,457
JBrowse link
G R Agpat5 1-acylglycerol-3-phosphate O-acyltransferase 5 decreases expression ISO obeticholic acid results in decreased expression of AGPAT5 mRNA CTD PMID:27939613 NCBI chr16:75,812,837...75,855,996
Ensembl chr16:75,812,997...75,855,745
JBrowse link
G M Agpat5 1-acylglycerol-3-phosphate O-acyltransferase 5 (lysophosphatidic acid acyltransferase, epsilon) decreases expression ISO obeticholic acid results in decreased expression of AGPAT5 mRNA CTD PMID:27939613 NCBI chr 8:18,846,279...18,884,413
Ensembl chr 8:18,846,277...18,891,361
JBrowse link
G H AGPAT5 1-acylglycerol-3-phosphate O-acyltransferase 5 decreases expression EXP obeticholic acid results in decreased expression of AGPAT5 mRNA CTD PMID:27939613 NCBI chr 8:6,708,587...6,761,503
Ensembl chr 8:6,708,642...6,761,503
JBrowse link
G R Akr1d1 aldo-keto reductase family 1, member D1 decreases expression ISO obeticholic acid results in decreased expression of AKR1D1 mRNA CTD PMID:27939613 NCBI chr 4:65,110,706...65,143,930
Ensembl chr 4:65,110,746...65,143,941
JBrowse link
G M Akr1d1 aldo-keto reductase family 1, member D1 decreases expression ISO obeticholic acid results in decreased expression of AKR1D1 mRNA CTD PMID:27939613 NCBI chr 6:37,529,978...37,574,921
Ensembl chr 6:37,530,173...37,568,815
JBrowse link
G H AKR1D1 aldo-keto reductase family 1 member D1 decreases expression EXP obeticholic acid results in decreased expression of AKR1D1 mRNA CTD PMID:27939613 NCBI chr 7:138,076,459...138,118,305
Ensembl chr 7:138,002,324...138,118,305
JBrowse link
G R Akt1 AKT serine/threonine kinase 1 multiple interactions
decreases expression
ISO obeticholic acid inhibits the reaction [Carbon Tetrachloride results in increased phosphorylation of AKT1 protein]
obeticholic acid results in decreased expression of AKT1 mRNA
CTD PMID:27865854 PMID:27939613 NCBI chr 6:137,218,398...137,239,970
Ensembl chr 6:137,218,376...137,236,258
JBrowse link
G M Akt1 thymoma viral proto-oncogene 1 decreases expression
multiple interactions
ISO
EXP
obeticholic acid results in decreased expression of AKT1 mRNA
obeticholic acid inhibits the reaction [Carbon Tetrachloride results in increased phosphorylation of AKT1 protein]
CTD PMID:27865854 PMID:27939613 NCBI chr12:112,653,821...112,674,884
Ensembl chr12:112,653,821...112,674,884
JBrowse link
G H AKT1 AKT serine/threonine kinase 1 decreases expression
multiple interactions
EXP
ISO
obeticholic acid results in decreased expression of AKT1 mRNA
obeticholic acid inhibits the reaction [Carbon Tetrachloride results in increased phosphorylation of AKT1 protein]
CTD PMID:27865854 PMID:27939613 NCBI chr14:104,769,349...104,795,748
Ensembl chr14:104,769,349...104,795,751
JBrowse link
G R Akt2 AKT serine/threonine kinase 2 decreases expression ISO obeticholic acid results in decreased expression of AKT2 mRNA CTD PMID:27939613 NCBI chr 1:84,400,939...84,451,223
Ensembl chr 1:84,411,726...84,450,162
JBrowse link
G M Akt2 thymoma viral proto-oncogene 2 decreases expression ISO obeticholic acid results in decreased expression of AKT2 mRNA CTD PMID:27939613 NCBI chr 7:27,591,552...27,640,826
Ensembl chr 7:27,591,552...27,640,826
JBrowse link
G H AKT2 AKT serine/threonine kinase 2 decreases expression EXP obeticholic acid results in decreased expression of AKT2 mRNA CTD PMID:27939613 NCBI chr19:40,230,317...40,285,531
Ensembl chr19:40,230,317...40,285,536
JBrowse link
G R Alb albumin decreases expression ISO obeticholic acid results in decreased expression of ALB mRNA CTD PMID:27939613 NCBI chr14:19,176,275...19,191,793
Ensembl chr14:19,176,277...19,191,863
JBrowse link
G M Alb albumin decreases expression ISO obeticholic acid results in decreased expression of ALB mRNA CTD PMID:27939613 NCBI chr 5:90,460,870...90,476,602
Ensembl chr 5:90,460,897...90,476,602
JBrowse link
G H ALB albumin decreases expression EXP obeticholic acid results in decreased expression of ALB mRNA CTD PMID:27939613 NCBI chr 4:73,404,287...73,421,482
Ensembl chr 4:73,397,114...73,421,482
JBrowse link
G R Aldoa aldolase, fructose-bisphosphate A decreases expression ISO obeticholic acid results in decreased expression of ALDOA mRNA CTD PMID:27939613 NCBI chr 1:198,228,387...198,233,988
Ensembl chr 1:198,228,387...198,233,588
JBrowse link
G H ALDOA aldolase, fructose-bisphosphate A decreases expression EXP obeticholic acid results in decreased expression of ALDOA mRNA CTD PMID:27939613 NCBI chr16:30,064,279...30,070,420
Ensembl chr16:30,064,164...30,070,457
Ensembl chr16:30,064,164...30,070,457
JBrowse link
G R Aldob aldolase, fructose-bisphosphate B decreases expression ISO obeticholic acid results in decreased expression of ALDOB mRNA CTD PMID:27939613 NCBI chr 5:64,805,772...64,818,813
Ensembl chr 5:64,805,773...64,818,824
JBrowse link
G M Aldob aldolase B, fructose-bisphosphate decreases expression ISO obeticholic acid results in decreased expression of ALDOB mRNA CTD PMID:27939613 NCBI chr 4:49,535,993...49,549,546
Ensembl chr 4:49,535,995...49,549,546
JBrowse link
G H ALDOB aldolase, fructose-bisphosphate B decreases expression EXP obeticholic acid results in decreased expression of ALDOB mRNA CTD PMID:27939613 NCBI chr 9:101,420,560...101,435,774
Ensembl chr 9:101,420,560...101,449,664
JBrowse link
G R Aldoc aldolase, fructose-bisphosphate C increases expression ISO obeticholic acid results in increased expression of ALDOC mRNA CTD PMID:27939613 NCBI chr10:65,586,504...65,590,093
Ensembl chr10:65,586,504...65,590,126
JBrowse link
G M Aldoc aldolase C, fructose-bisphosphate increases expression ISO obeticholic acid results in increased expression of ALDOC mRNA CTD PMID:27939613 NCBI chr11:78,323,073...78,327,781
Ensembl chr11:78,322,968...78,327,781
JBrowse link
G H ALDOC aldolase, fructose-bisphosphate C increases expression EXP obeticholic acid results in increased expression of ALDOC mRNA CTD PMID:27939613 NCBI chr17:28,573,115...28,576,963
Ensembl chr17:28,573,115...28,576,948
JBrowse link
G R Amn amnion associated transmembrane protein decreases expression ISO obeticholic acid results in decreased expression of AMN mRNA CTD PMID:27939613 NCBI chr 6:135,724,455...135,731,896
Ensembl chr 6:135,724,455...135,731,896
JBrowse link
G M Amn amnionless decreases expression ISO obeticholic acid results in decreased expression of AMN mRNA CTD PMID:27939613 NCBI chr12:111,271,096...111,276,426
Ensembl chr12:111,271,095...111,276,426
JBrowse link
G H AMN amnion associated transmembrane protein decreases expression EXP obeticholic acid results in decreased expression of AMN mRNA CTD PMID:27939613 NCBI chr14:102,922,430...102,933,597
Ensembl chr14:102,922,656...102,933,596
Ensembl chr14:102,922,656...102,933,596
JBrowse link
G H AOC4P amine oxidase copper containing 4, pseudogene increases expression EXP obeticholic acid results in increased expression of AOC4P mRNA CTD PMID:27939613 NCBI chr17:42,867,145...42,869,217
Ensembl chr17:42,865,922...42,874,369
JBrowse link
G R Apoa1 apolipoprotein A1 decreases expression ISO obeticholic acid results in decreased expression of APOA1 mRNA CTD PMID:27939613 NCBI chr 8:50,525,091...50,526,875
Ensembl chr 8:50,525,091...50,526,875
JBrowse link
G M Apoa1 apolipoprotein A-I decreases expression ISO obeticholic acid results in decreased expression of APOA1 mRNA CTD PMID:27939613 NCBI chr 9:46,228,630...46,230,469
Ensembl chr 9:46,228,580...46,230,466
JBrowse link
G H APOA1 apolipoprotein A1 decreases expression EXP obeticholic acid results in decreased expression of APOA1 mRNA CTD PMID:27939613 NCBI chr11:116,835,751...116,837,950
Ensembl chr11:116,835,751...116,837,622
Ensembl chr11:116,835,751...116,837,622
JBrowse link
G R Apoa2 apolipoprotein A2 increases expression ISO obeticholic acid results in increased expression of APOA2 mRNA CTD PMID:27939613 NCBI chr13:89,596,872...89,598,805
Ensembl chr13:89,597,138...89,598,802
JBrowse link
G M Apoa2 apolipoprotein A-II increases expression ISO obeticholic acid results in increased expression of APOA2 mRNA CTD PMID:27939613 NCBI chr 1:171,221,564...171,226,379
Ensembl chr 1:171,225,054...171,226,379
JBrowse link
G H APOA2 apolipoprotein A2 increases expression EXP obeticholic acid results in increased expression of APOA2 mRNA CTD PMID:27939613 NCBI chr 1:161,222,292...161,223,628
Ensembl chr 1:161,222,292...161,223,631
JBrowse link
G R Apob apolipoprotein B increases expression ISO obeticholic acid results in increased expression of APOB mRNA CTD PMID:27939613 NCBI chr 6:33,176,826...33,216,381
Ensembl chr 6:33,176,778...33,224,997
JBrowse link
G M Apob apolipoprotein B increases expression ISO obeticholic acid results in increased expression of APOB mRNA CTD PMID:27939613 NCBI chr12:7,977,629...8,016,839
Ensembl chr12:7,977,648...8,016,835
JBrowse link
G H APOB apolipoprotein B increases expression EXP obeticholic acid results in increased expression of APOB mRNA CTD PMID:27939613 NCBI chr 2:21,001,429...21,044,073
Ensembl chr 2:21,001,429...21,044,073
JBrowse link
G R Apoc2 apolipoprotein C2 increases expression ISO obeticholic acid results in increased expression of APOC2 mRNA CTD PMID:27939613 NCBI chr 1:80,589,023...80,593,991
Ensembl chr 1:80,589,023...80,594,136
JBrowse link
G M Apoc2 apolipoprotein C-II increases expression ISO obeticholic acid results in increased expression of APOC2 mRNA CTD PMID:27939613 NCBI chr 7:19,671,579...19,677,941
Ensembl chr 7:19,671,579...19,677,941
JBrowse link
G H APOC2 apolipoprotein C2 increases expression EXP obeticholic acid results in increased expression of APOC2 mRNA CTD PMID:27939613 NCBI chr19:44,946,051...44,949,565
Ensembl chr19:44,945,971...44,949,566
Ensembl chr19:44,945,971...44,949,566
JBrowse link
G R Apoc3 apolipoprotein C3 decreases expression ISO obeticholic acid results in decreased expression of APOC3 mRNA CTD PMID:27939613 NCBI chr 8:50,529,318...50,531,498
Ensembl chr 8:50,529,318...50,531,498
JBrowse link
G M Apoc3 apolipoprotein C-III decreases expression ISO obeticholic acid results in decreased expression of APOC3 mRNA CTD PMID:27939613 NCBI chr 9:46,233,050...46,235,636
Ensembl chr 9:46,232,933...46,235,636
JBrowse link
G H APOC3 apolipoprotein C3 decreases expression EXP obeticholic acid results in decreased expression of APOC3 mRNA CTD PMID:27939613 NCBI chr11:116,829,907...116,833,072
Ensembl chr11:116,829,706...116,833,072
JBrowse link
G R Apoe apolipoprotein E decreases expression ISO obeticholic acid results in decreased expression of APOE mRNA CTD PMID:27939613 NCBI chr 1:80,612,894...80,616,820
Ensembl chr 1:80,612,895...80,617,057
JBrowse link
G M Apoe apolipoprotein E decreases expression ISO obeticholic acid results in decreased expression of APOE mRNA CTD PMID:27939613 NCBI chr 7:19,696,244...19,701,310
Ensembl chr 7:19,696,109...19,699,188
JBrowse link
G H APOE apolipoprotein E decreases expression EXP obeticholic acid results in decreased expression of APOE mRNA CTD PMID:27939613 NCBI chr19:44,905,796...44,909,393
Ensembl chr19:44,905,791...44,909,393
JBrowse link
G R Aspg asparaginase decreases expression ISO obeticholic acid results in decreased expression of ASPG mRNA CTD PMID:27939613 NCBI chr 6:136,682,279...136,701,673
Ensembl chr 6:136,682,126...136,701,628
JBrowse link
G M Aspg asparaginase decreases expression ISO obeticholic acid results in decreased expression of ASPG mRNA CTD PMID:27939613 NCBI chr12:112,106,683...112,127,573
Ensembl chr12:112,106,679...112,127,559
JBrowse link
G H ASPG asparaginase decreases expression EXP obeticholic acid results in decreased expression of ASPG mRNA CTD PMID:27939613 NCBI chr14:104,085,658...104,115,582
Ensembl chr14:104,085,686...104,115,582
JBrowse link
G R Bad BCL2-associated agonist of cell death decreases expression ISO obeticholic acid results in decreased expression of BAD mRNA CTD PMID:27939613 NCBI chr 1:222,198,516...222,207,459
Ensembl chr 1:222,198,534...222,207,453
JBrowse link
G M Bad BCL2-associated agonist of cell death decreases expression ISO obeticholic acid results in decreased expression of BAD mRNA CTD PMID:27939613 NCBI chr19:6,941,861...6,951,905
Ensembl chr19:6,941,861...6,951,899
JBrowse link
G H BAD BCL2 associated agonist of cell death decreases expression EXP obeticholic acid results in decreased expression of BAD mRNA CTD PMID:27939613 NCBI chr11:64,269,828...64,284,704
Ensembl chr11:64,269,830...64,284,704
JBrowse link
G R Bcl2 BCL2, apoptosis regulator increases expression ISO obeticholic acid results in increased expression of BCL2 mRNA CTD PMID:27939613 NCBI chr13:26,605,426...26,769,374
Ensembl chr13:26,605,426...26,769,374
JBrowse link
G M Bcl2 B cell leukemia/lymphoma 2 increases expression ISO obeticholic acid results in increased expression of BCL2 mRNA CTD PMID:27939613 NCBI chr 1:106,538,176...106,714,290
Ensembl chr 1:106,538,178...106,714,274
JBrowse link
G H BCL2 BCL2 apoptosis regulator increases expression EXP obeticholic acid results in increased expression of BCL2 mRNA CTD PMID:27939613 NCBI chr18:63,123,346...63,320,280
Ensembl chr18:63,123,346...63,320,128
JBrowse link
G R Bid BH3 interacting domain death agonist decreases expression ISO obeticholic acid results in decreased expression of BID mRNA CTD PMID:27939613 NCBI chr 4:153,439,812...153,465,247
Ensembl chr 4:153,442,218...153,465,203
JBrowse link
G M Bid BH3 interacting domain death agonist decreases expression ISO obeticholic acid results in decreased expression of BID mRNA CTD PMID:27939613 NCBI chr 6:120,893,119...120,917,062
Ensembl chr 6:120,891,930...120,916,853
JBrowse link
G H BID BH3 interacting domain death agonist decreases expression EXP obeticholic acid results in decreased expression of BID mRNA CTD PMID:27939613 NCBI chr22:17,734,138...17,774,665
Ensembl chr22:17,734,138...17,774,770
JBrowse link
G R Birc3 baculoviral IAP repeat-containing 3 decreases expression ISO obeticholic acid results in decreased expression of BIRC3 mRNA CTD PMID:27939613 NCBI chr 8:6,048,590...6,076,828
Ensembl chr 8:6,048,969...6,076,598
JBrowse link
G M Birc3 baculoviral IAP repeat-containing 3 decreases expression ISO obeticholic acid results in decreased expression of BIRC3 mRNA CTD PMID:27939613 NCBI chr 9:7,847,468...7,873,205
Ensembl chr 9:7,848,699...7,873,186
JBrowse link
G H BIRC3 baculoviral IAP repeat containing 3 decreases expression EXP obeticholic acid results in decreased expression of BIRC3 mRNA CTD PMID:27939613 NCBI chr11:102,317,373...102,339,403
Ensembl chr11:102,317,450...102,339,403
JBrowse link
G R C5ar2 complement C5a receptor 2 decreases expression ISO obeticholic acid results in decreased expression of C5AR2 mRNA CTD PMID:27939613 NCBI chr 1:78,165,155...78,183,426
Ensembl chr 1:78,166,810...78,180,216
JBrowse link
G M C5ar2 complement component 5a receptor 2 decreases expression ISO obeticholic acid results in decreased expression of C5AR2 mRNA CTD PMID:27939613 NCBI chr 7:16,234,587...16,244,154
Ensembl chr 7:16,234,585...16,244,154
JBrowse link
G H C5AR2 complement C5a receptor 2 decreases expression EXP obeticholic acid results in decreased expression of C5AR2 mRNA CTD PMID:27939613 NCBI chr19:47,331,614...47,347,329
Ensembl chr19:47,332,175...47,347,329
JBrowse link
G R Ca14 carbonic anhydrase 14 increases expression ISO obeticholic acid results in increased expression of CA14 mRNA CTD PMID:27939613 NCBI chr 2:198,010,142...198,017,635
Ensembl chr 2:198,010,349...198,016,898
JBrowse link
G H CA14 carbonic anhydrase 14 increases expression EXP obeticholic acid results in increased expression of CA14 mRNA CTD PMID:27939613 NCBI chr 1:150,257,258...150,265,862
Ensembl chr 1:150,257,251...150,265,078
JBrowse link
G M Car14 carbonic anhydrase 14 increases expression ISO obeticholic acid results in increased expression of CA14 mRNA CTD PMID:27939613 NCBI chr 3:95,897,768...95,905,117
Ensembl chr 3:95,897,768...95,904,691
JBrowse link
G H CASP10 caspase 10 increases expression EXP obeticholic acid results in increased expression of CASP10 mRNA CTD PMID:27939613 NCBI chr 2:201,182,885...201,229,406
Ensembl chr 2:201,182,898...201,229,406
Ensembl chr 2:201,182,898...201,229,406
JBrowse link
G R Casp3 caspase 3 multiple interactions EXP
ISO
obeticholic acid promotes the reaction [Cycloheximide results in increased activity of CASP3 protein]
obeticholic acid inhibits the reaction [Dietary Fats results in increased expression of CASP3 protein]
CTD PMID:15860571 PMID:26655953 NCBI chr16:48,845,011...48,863,249
Ensembl chr16:48,845,012...48,863,204
JBrowse link
G M Casp3 caspase 3 multiple interactions ISO
EXP
obeticholic acid promotes the reaction [Cycloheximide results in increased activity of CASP3 protein]
obeticholic acid inhibits the reaction [Dietary Fats results in increased expression of CASP3 protein]
CTD PMID:15860571 PMID:26655953 NCBI chr 8:46,617,291...46,639,698
Ensembl chr 8:46,617,291...46,639,689
JBrowse link
G H CASP3 caspase 3 multiple interactions ISO obeticholic acid promotes the reaction [Cycloheximide results in increased activity of CASP3 protein]
obeticholic acid inhibits the reaction [Dietary Fats results in increased expression of CASP3 protein]
CTD PMID:15860571 PMID:26655953 NCBI chr 4:184,627,696...184,649,447
Ensembl chr 4:184,627,696...184,649,509
JBrowse link
G R Casp8 caspase 8 increases expression ISO obeticholic acid results in increased expression of CASP8 mRNA CTD PMID:27939613 NCBI chr 9:65,614,142...65,662,624
Ensembl chr 9:65,614,142...65,662,106
JBrowse link
G M Casp8 caspase 8 increases expression ISO obeticholic acid results in increased expression of CASP8 mRNA CTD PMID:27939613 NCBI chr 1:58,795,233...58,847,503
Ensembl chr 1:58,795,374...58,847,503
JBrowse link
G H CASP8 caspase 8 increases expression EXP obeticholic acid results in increased expression of CASP8 mRNA CTD PMID:27939613 NCBI chr 2:201,233,443...201,287,711
Ensembl chr 2:201,233,443...201,287,711
JBrowse link
G R Ccl2 C-C motif chemokine ligand 2 multiple interactions ISO obeticholic acid inhibits the reaction [Carbon Tetrachloride results in increased expression of CCL2 mRNA] CTD PMID:27865854 NCBI chr10:69,412,065...69,413,863
Ensembl chr10:69,412,017...69,413,870
JBrowse link
G M Ccl2 chemokine (C-C motif) ligand 2 multiple interactions EXP obeticholic acid inhibits the reaction [Carbon Tetrachloride results in increased expression of CCL2 mRNA] CTD PMID:27865854 NCBI chr11:82,035,577...82,037,452
Ensembl chr11:82,035,571...82,037,453
JBrowse link
G H CCL2 C-C motif chemokine ligand 2 multiple interactions ISO obeticholic acid inhibits the reaction [Carbon Tetrachloride results in increased expression of CCL2 mRNA] CTD PMID:27865854 NCBI chr17:34,255,285...34,257,203
Ensembl chr17:34,255,218...34,257,203
JBrowse link
G R Ccnb1 cyclin B1 multiple interactions ISO obeticholic acid promotes the reaction [1-Naphthylisothiocyanate results in increased expression of CCNB1 protein] CTD PMID:29660435 NCBI chr 2:30,782,133...30,791,106
Ensembl chr 2:30,783,915...30,791,221
JBrowse link
G M Ccnb1 cyclin B1 multiple interactions EXP obeticholic acid promotes the reaction [1-Naphthylisothiocyanate results in increased expression of CCNB1 protein] CTD PMID:29660435 NCBI chr13:100,778,739...100,786,486
Ensembl chr13:100,778,650...100,786,570
JBrowse link
G H CCNB1 cyclin B1 multiple interactions ISO obeticholic acid promotes the reaction [1-Naphthylisothiocyanate results in increased expression of CCNB1 protein] CTD PMID:29660435 NCBI chr 5:69,167,150...69,178,245
Ensembl chr 5:69,167,135...69,178,245
JBrowse link
G R Ccnd1 cyclin D1 multiple interactions ISO obeticholic acid promotes the reaction [1-Naphthylisothiocyanate results in increased expression of CCND1 protein] CTD PMID:29660435 NCBI chr 1:218,090,750...218,100,447
Ensembl chr 1:218,090,750...218,100,325
JBrowse link
G M Ccnd1 cyclin D1 multiple interactions EXP obeticholic acid promotes the reaction [1-Naphthylisothiocyanate results in increased expression of CCND1 protein] CTD PMID:29660435 NCBI chr 7:144,929,931...144,939,831
Ensembl chr 7:144,929,931...144,939,925
JBrowse link
G H CCND1 cyclin D1 multiple interactions ISO obeticholic acid promotes the reaction [1-Naphthylisothiocyanate results in increased expression of CCND1 protein] CTD PMID:29660435 NCBI chr11:69,641,156...69,654,474
Ensembl chr11:69,641,156...69,654,474
Ensembl chr11:69,641,156...69,654,474
JBrowse link
G R Ccs copper chaperone for superoxide dismutase decreases expression ISO obeticholic acid results in decreased expression of CCS mRNA CTD PMID:27939613 NCBI chr 1:220,075,251...220,096,319
Ensembl chr 1:220,075,247...220,096,404
JBrowse link
G M Ccs copper chaperone for superoxide dismutase decreases expression ISO obeticholic acid results in decreased expression of CCS mRNA CTD PMID:27939613 NCBI chr19:4,825,366...4,839,356
Ensembl chr19:4,825,366...4,839,332
JBrowse link
G H CCS copper chaperone for superoxide dismutase decreases expression EXP obeticholic acid results in decreased expression of CCS mRNA CTD PMID:27939613 NCBI chr11:66,593,162...66,606,019
Ensembl chr11:66,593,153...66,606,019
JBrowse link
G R Cd14 CD14 molecule decreases expression ISO obeticholic acid results in decreased expression of CD14 mRNA CTD PMID:27939613 NCBI chr18:29,560,341...29,562,290
Ensembl chr18:29,560,365...29,562,153
JBrowse link
G M Cd14 CD14 antigen decreases expression ISO obeticholic acid results in decreased expression of CD14 mRNA CTD PMID:27939613 NCBI chr18:36,725,064...36,726,815
Ensembl chr18:36,725,067...36,726,798
JBrowse link
G H CD14 CD14 molecule decreases expression EXP obeticholic acid results in decreased expression of CD14 mRNA CTD PMID:27939613 NCBI chr 5:140,631,732...140,633,701
Ensembl chr 5:140,631,728...140,633,701
JBrowse link
G R Clic4 chloride intracellular channel 4 increases expression ISO obeticholic acid results in increased expression of CLIC4 mRNA CTD PMID:27939613 NCBI chr 5:153,568,937...153,625,669
Ensembl chr 5:153,568,745...153,625,869
JBrowse link
G M Clic4 chloride intracellular channel 4 (mitochondrial) increases expression ISO obeticholic acid results in increased expression of CLIC4 mRNA CTD PMID:27939613 NCBI chr 4:135,213,969...135,272,760
Ensembl chr 4:135,213,969...135,272,814
JBrowse link
G H CLIC4 chloride intracellular channel 4 increases expression EXP obeticholic acid results in increased expression of CLIC4 mRNA CTD PMID:27939613 NCBI chr 1:24,745,447...24,844,321
Ensembl chr 1:24,745,382...24,844,321
JBrowse link
G R Col1a1 collagen type I alpha 1 chain decreases expression
multiple interactions
EXP
ISO
obeticholic acid results in decreased expression of COL1A1 mRNA; obeticholic acid results in decreased expression of COL1A1 protein
obeticholic acid inhibits the reaction [[Methionine deficiency co-treated with Choline deficiency] results in increased expression of COL1A1 mRNA]
obeticholic acid inhibits the reaction [TGFB1 protein results in increased expression of COL1A1 mRNA]
CTD PMID:15860571 PMID:15980055 PMID:27939613 PMID:30745416 NCBI chr10:82,745,801...82,762,790
Ensembl chr10:82,745,801...82,762,789
JBrowse link
G M Col1a1 collagen, type I, alpha 1 decreases expression
multiple interactions
ISO
EXP
obeticholic acid results in decreased expression of COL1A1 mRNA; obeticholic acid results in decreased expression of COL1A1 protein
obeticholic acid inhibits the reaction [[Methionine deficiency co-treated with Choline deficiency] results in increased expression of COL1A1 mRNA]
obeticholic acid inhibits the reaction [TGFB1 protein results in increased expression of COL1A1 mRNA]
CTD PMID:15860571 PMID:15980055 PMID:27939613 PMID:30745416 NCBI chr11:94,936,224...94,953,042
Ensembl chr11:94,936,224...94,953,042
JBrowse link
G H COL1A1 collagen type I alpha 1 chain decreases expression
multiple interactions
ISO
EXP
obeticholic acid results in decreased expression of COL1A1 mRNA; obeticholic acid results in decreased expression of COL1A1 protein
obeticholic acid inhibits the reaction [[Methionine deficiency co-treated with Choline deficiency] results in increased expression of COL1A1 mRNA]
obeticholic acid inhibits the reaction [TGFB1 protein results in increased expression of COL1A1 mRNA]
CTD PMID:15860571 PMID:15980055 PMID:27939613 PMID:30745416 NCBI chr17:50,184,096...50,201,649
Ensembl chr17:50,183,289...50,201,632
Ensembl chr17:50,183,289...50,201,632
JBrowse link
G R Cpt1a carnitine palmitoyltransferase 1A multiple interactions
increases expression
ISO
EXP
obeticholic acid promotes the reaction [Palmitic Acid results in increased expression of CPT1A mRNA]
Obeticholic acid inhibits the reaction [ethanol decreases expression of CPT1a mRNA and protein in liver]
obeticholic acid inhibits the reaction [Ethanol results in decreased expression of CPT1A protein]
obeticholic acid results in increased expression of CPT1A mRNA
CTD PMID:26655953 PMID:27939613 PMID:27939985, PMID:27939985 RGD:15036816 NCBI chr 1:218,568,157...218,629,679
Ensembl chr 1:218,569,510...218,629,678
JBrowse link
G M Cpt1a carnitine palmitoyltransferase 1a, liver multiple interactions
increases expression
EXP
ISO
obeticholic acid promotes the reaction [Palmitic Acid results in increased expression of CPT1A mRNA]
Obeticholic acid inhibits the reaction [ethanol decreases expression of CPT1a mRNA and protein in liver]
obeticholic acid results in increased expression of CPT1A mRNA
obeticholic acid inhibits the reaction [Ethanol results in decreased expression of CPT1A protein]
CTD PMID:26655953 PMID:27939613 PMID:27939985, PMID:27939985 RGD:15036816 NCBI chr19:3,322,326...3,385,735
Ensembl chr19:3,322,334...3,385,733
JBrowse link
G H CPT1A carnitine palmitoyltransferase 1A multiple interactions
increases expression
ISO
EXP
obeticholic acid promotes the reaction [Palmitic Acid results in increased expression of CPT1A mRNA]
Obeticholic acid inhibits the reaction [ethanol decreases expression of CPT1a mRNA and protein in liver]
obeticholic acid inhibits the reaction [Ethanol results in decreased expression of CPT1A protein]
obeticholic acid results in increased expression of CPT1A mRNA
CTD PMID:26655953 PMID:27939613 PMID:27939985, PMID:27939985 RGD:15036816 NCBI chr11:68,754,620...68,844,410
Ensembl chr11:68,754,620...68,844,410
JBrowse link
G R Cpt2 carnitine palmitoyltransferase 2 increases expression ISO obeticholic acid results in increased expression of CPT2 mRNA CTD PMID:27939613 NCBI chr 5:127,505,646...127,523,016
Ensembl chr 5:127,505,614...127,523,089
JBrowse link
G M Cpt2 carnitine palmitoyltransferase 2 increases expression ISO obeticholic acid results in increased expression of CPT2 mRNA CTD PMID:27939613 NCBI chr 4:107,903,982...107,923,589
Ensembl chr 4:107,903,981...107,923,610
JBrowse link
G H CPT2 carnitine palmitoyltransferase 2 increases expression EXP obeticholic acid results in increased expression of CPT2 mRNA CTD PMID:27939613 NCBI chr 1:53,196,824...53,214,197
Ensembl chr 1:53,196,792...53,214,197
JBrowse link
G R Crct1 cysteine-rich C-terminal 1 decreases expression ISO obeticholic acid results in decreased expression of CRCT1 mRNA CTD PMID:27939613 Ensembl chr 2:193,330,397...193,330,699 JBrowse link
G M Crct1 cysteine-rich C-terminal 1 decreases expression ISO obeticholic acid results in decreased expression of CRCT1 mRNA CTD PMID:27939613 NCBI chr 3:93,014,205...93,015,686
Ensembl chr 3:93,014,205...93,015,687
JBrowse link
G H CRCT1 cysteine rich C-terminal 1 decreases expression EXP obeticholic acid results in decreased expression of CRCT1 mRNA CTD PMID:27939613 NCBI chr 1:152,514,482...152,516,010
Ensembl chr 1:152,514,482...152,516,008
JBrowse link
G R Creb3l1 cAMP responsive element binding protein 3-like 1 decreases expression ISO obeticholic acid results in decreased expression of CREB3L1 mRNA CTD PMID:27939613 NCBI chr 3:80,892,433...80,933,283
Ensembl chr 3:80,892,435...80,933,283
JBrowse link
G M Creb3l1 cAMP responsive element binding protein 3-like 1 decreases expression ISO obeticholic acid results in decreased expression of CREB3L1 mRNA CTD PMID:27939613 NCBI chr 2:91,982,328...92,024,170
Ensembl chr 2:91,982,328...92,024,502
JBrowse link
G H CREB3L1 cAMP responsive element binding protein 3 like 1 decreases expression EXP obeticholic acid results in decreased expression of CREB3L1 mRNA CTD PMID:27939613 NCBI chr11:46,277,661...46,321,409
Ensembl chr11:46,277,662...46,321,409
JBrowse link
G R Creb3l3 cAMP responsive element binding protein 3-like 3 increases expression ISO obeticholic acid results in increased expression of CREB3L3 mRNA CTD PMID:27939613 NCBI chr 7:11,490,852...11,499,287
Ensembl chr 7:11,490,852...11,499,282
JBrowse link
G M Creb3l3 cAMP responsive element binding protein 3-like 3 increases expression ISO obeticholic acid results in increased expression of CREB3L3 mRNA CTD PMID:27939613 NCBI chr10:81,084,329...81,098,872
Ensembl chr10:81,084,324...81,098,874
JBrowse link
G H CREB3L3 cAMP responsive element binding protein 3 like 3 increases expression EXP obeticholic acid results in increased expression of CREB3L3 mRNA CTD PMID:27939613 NCBI chr19:4,153,631...4,173,054
Ensembl chr19:4,153,631...4,173,054
JBrowse link
G R Crp C-reactive protein decreases expression ISO obeticholic acid results in decreased expression of CRP mRNA CTD PMID:27939613 NCBI chr13:91,080,448...91,081,358
Ensembl chr13:91,054,974...91,093,713
JBrowse link
G M Crp C-reactive protein, pentraxin-related decreases expression ISO obeticholic acid results in decreased expression of CRP mRNA CTD PMID:27939613 NCBI chr 1:172,698,056...172,699,966
Ensembl chr 1:172,698,055...172,833,031
JBrowse link
G H CRP C-reactive protein decreases expression EXP obeticholic acid results in decreased expression of CRP mRNA CTD PMID:27939613 NCBI chr 1:159,712,289...159,714,589
Ensembl chr 1:159,712,289...159,714,589
JBrowse link
G H CTAGE15 CTAGE family member 15 increases expression EXP obeticholic acid results in increased expression of CTAGE15 mRNA CTD PMID:27939613 NCBI chr 7:143,571,801...143,574,387
Ensembl chr 7:143,571,801...143,574,387
JBrowse link
G H CXCL1 C-X-C motif chemokine ligand 1 multiple interactions ISO obeticholic acid inhibits the reaction [Carbon Tetrachloride results in increased expression of CXCL1 mRNA] CTD PMID:27865854 NCBI chr 4:73,869,393...73,871,308
Ensembl chr 4:73,869,393...73,871,308
JBrowse link
G R Cxcl2 C-X-C motif chemokine ligand 2 multiple interactions ISO obeticholic acid inhibits the reaction [Carbon Tetrachloride results in increased expression of CXCL2 mRNA] CTD PMID:27865854 NCBI chr14:18,731,346...18,733,391
Ensembl chr14:18,731,378...18,733,391
JBrowse link
G M Cxcl2 chemokine (C-X-C motif) ligand 2 multiple interactions EXP obeticholic acid inhibits the reaction [Carbon Tetrachloride results in increased expression of CXCL2 mRNA] CTD PMID:27865854 NCBI chr 5:90,903,899...90,905,938
Ensembl chr 5:90,903,871...90,905,938
JBrowse link
G H CXCL2 C-X-C motif chemokine ligand 2 multiple interactions ISO obeticholic acid inhibits the reaction [Carbon Tetrachloride results in increased expression of CXCL2 mRNA] CTD PMID:27865854 NCBI chr 4:74,097,040...74,099,195
Ensembl chr 4:74,097,040...74,099,196
JBrowse link
G R Cxcl3 C-X-C motif chemokine ligand 3 multiple interactions ISO obeticholic acid inhibits the reaction [Carbon Tetrachloride results in increased expression of CXCL1 mRNA] CTD PMID:27865854 NCBI chr14:18,820,168...18,839,659
Ensembl chr14:18,820,168...18,839,595
JBrowse link
G M Cxcl3 chemokine (C-X-C motif) ligand 3 multiple interactions EXP obeticholic acid inhibits the reaction [Carbon Tetrachloride results in increased expression of CXCL1 mRNA] CTD PMID:27865854 NCBI chr 5:90,786,101...90,788,093
Ensembl chr 5:90,786,103...90,789,600
JBrowse link
G R Cyp19a1 cytochrome P450, family 19, subfamily a, polypeptide 1 decreases expression ISO obeticholic acid results in decreased expression of CYP19A1 mRNA CTD PMID:27939613 NCBI chr 8:58,744,849...58,772,408
Ensembl chr 8:58,744,849...58,772,408
JBrowse link
G M Cyp19a1 cytochrome P450, family 19, subfamily a, polypeptide 1 decreases expression ISO obeticholic acid results in decreased expression of CYP19A1 mRNA CTD PMID:27939613 NCBI chr 9:54,165,937...54,268,164
Ensembl chr 9:54,165,937...54,268,110
JBrowse link
G H CYP19A1 cytochrome P450 family 19 subfamily A member 1 decreases expression EXP obeticholic acid results in decreased expression of CYP19A1 mRNA CTD PMID:27939613 NCBI chr15:51,208,057...51,338,596
Ensembl chr15:51,208,057...51,338,601
JBrowse link
G R Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 decreases expression ISO obeticholic acid results in decreased expression of CYP1A1 mRNA CTD PMID:27939613 NCBI chr 8:62,472,087...62,478,122
Ensembl chr 8:62,472,095...62,478,147
JBrowse link
G M Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 decreases expression ISO obeticholic acid results in decreased expression of CYP1A1 mRNA CTD PMID:27939613 NCBI chr 9:57,687,928...57,703,824
Ensembl chr 9:57,687,928...57,703,824
JBrowse link
G H CYP1A1 cytochrome P450 family 1 subfamily A member 1 decreases expression EXP obeticholic acid results in decreased expression of CYP1A1 mRNA CTD PMID:27939613 NCBI chr15:74,719,542...74,725,528
Ensembl chr15:74,719,542...74,725,536
JBrowse link
G R Cyp1a2 cytochrome P450, family 1, subfamily a, polypeptide 2 multiple interactions
decreases activity
decreases expression
ISO obeticholic acid inhibits the reaction [CYP1A2 protein results in increased chemical synthesis of Acetaminophen]; obeticholic acid inhibits the reaction [CYP1A2 protein results in increased metabolism of Phenacetin]
obeticholic acid results in decreased activity of CYP1A2 protein
obeticholic acid results in decreased expression of CYP1A2 mRNA
CTD PMID:27939613 NCBI chr 8:62,451,360...62,458,244
Ensembl chr 8:62,451,329...62,458,301
JBrowse link
G M Cyp1a2 cytochrome P450, family 1, subfamily a, polypeptide 2 decreases expression
multiple interactions
decreases activity
ISO obeticholic acid results in decreased expression of CYP1A2 mRNA
obeticholic acid inhibits the reaction [CYP1A2 protein results in increased chemical synthesis of Acetaminophen]; obeticholic acid inhibits the reaction [CYP1A2 protein results in increased metabolism of Phenacetin]
obeticholic acid results in decreased activity of CYP1A2 protein
CTD PMID:27939613 NCBI chr 9:57,676,937...57,683,655
Ensembl chr 9:57,676,937...57,683,703
JBrowse link
G H CYP1A2 cytochrome P450 family 1 subfamily A member 2 decreases expression
decreases activity
multiple interactions
EXP obeticholic acid results in decreased expression of CYP1A2 mRNA
obeticholic acid results in decreased activity of CYP1A2 protein
obeticholic acid inhibits the reaction [CYP1A2 protein results in increased chemical synthesis of Acetaminophen]; obeticholic acid inhibits the reaction [CYP1A2 protein results in increased metabolism of Phenacetin]
CTD PMID:27939613 NCBI chr15:74,748,845...74,756,607
Ensembl chr15:74,748,845...74,756,607
JBrowse link
G M Cyp21a1 cytochrome P450, family 21, subfamily a, polypeptide 1 decreases expression ISO obeticholic acid results in decreased expression of CYP21A2 mRNA CTD PMID:27939613 NCBI chr17:34,801,348...34,804,426
Ensembl chr17:34,801,348...34,804,561
JBrowse link
G H CYP21A2 cytochrome P450 family 21 subfamily A member 2 decreases expression EXP obeticholic acid results in decreased expression of CYP21A2 mRNA CTD PMID:27939613 NCBI chr 6:32,038,415...32,041,644
Ensembl chr 6:32,038,327...32,041,644
JBrowse link
G R Cyp27a1 cytochrome P450, family 27, subfamily a, polypeptide 1 decreases expression ISO obeticholic acid results in decreased expression of CYP27A1 mRNA CTD PMID:27939613 NCBI chr 9:81,968,285...81,998,213
Ensembl chr 9:81,968,332...81,998,169
JBrowse link
G M Cyp27a1 cytochrome P450, family 27, subfamily a, polypeptide 1 decreases expression ISO obeticholic acid results in decreased expression of CYP27A1 mRNA CTD PMID:27939613 NCBI chr 1:74,713,148...74,737,897
Ensembl chr 1:74,713,574...74,737,892
JBrowse link
G H CYP27A1 cytochrome P450 family 27 subfamily A member 1 decreases expression EXP obeticholic acid results in decreased expression of CYP27A1 mRNA CTD PMID:27939613 NCBI chr 2:218,781,733...218,815,293
Ensembl chr 2:218,781,749...218,815,293
JBrowse link
G M Cyp2a5 cytochrome P450, family 2, subfamily a, polypeptide 5 increases expression ISO obeticholic acid results in increased expression of CYP2A6 mRNA CTD PMID:27939613 NCBI chr 7:26,835,339...26,843,264
Ensembl chr 7:26,835,305...26,843,548
JBrowse link
G H CYP2A6 cytochrome P450 family 2 subfamily A member 6 increases expression EXP obeticholic acid results in increased expression of CYP2A6 mRNA CTD PMID:27939613 NCBI chr19:40,843,541...40,850,447
Ensembl chr19:40,843,541...40,850,447
JBrowse link
G M Cyp2c29 cytochrome P450, family 2, subfamily c, polypeptide 29 decreases expression ISO obeticholic acid results in decreased expression of CYP2C8 mRNA CTD PMID:27939613 NCBI chr19:39,287,044...39,330,713
Ensembl chr19:39,269,405...39,330,713
JBrowse link
G M Cyp2c65 cytochrome P450, family 2, subfamily c, polypeptide 65 decreases expression ISO obeticholic acid results in decreased expression of CYP2C9 mRNA CTD PMID:27939613 NCBI chr19:39,061,006...39,093,948
Ensembl chr19:39,061,015...39,093,944
JBrowse link
G M Cyp2c66 cytochrome P450, family 2, subfamily c, polypeptide 66 decreases expression ISO obeticholic acid results in decreased expression of CYP2C9 mRNA CTD PMID:27939613 NCBI chr19:39,113,898...39,186,756
Ensembl chr19:39,113,898...39,187,072
JBrowse link
G R Cyp2c79 cytochrome P450, family 2, subfamily c, polypeptide 79 decreases expression ISO obeticholic acid results in decreased expression of CYP2C8 mRNA CTD PMID:27939613 NCBI chr 1:147,236,480...147,307,988 JBrowse link
G H CYP2C8 cytochrome P450 family 2 subfamily C member 8 decreases expression EXP obeticholic acid results in decreased expression of CYP2C8 mRNA CTD PMID:27939613 NCBI chr10:95,036,772...95,069,497
Ensembl chr10:95,036,772...95,069,497
JBrowse link
G H CYP2C9 cytochrome P450 family 2 subfamily C member 9 decreases expression EXP obeticholic acid results in decreased expression of CYP2C9 mRNA CTD PMID:27939613 NCBI chr10:94,938,658...94,990,091
Ensembl chr10:94,938,658...94,990,091
JBrowse link
G M Cyp2d22 cytochrome P450, family 2, subfamily d, polypeptide 22 increases expression ISO obeticholic acid results in increased expression of CYP2D6 mRNA CTD PMID:27939613 NCBI chr15:82,370,527...82,380,260
Ensembl chr15:82,370,527...82,380,260
JBrowse link
G R Cyp2d4 cytochrome P450, family 2, subfamily d, polypeptide 4 increases expression ISO obeticholic acid results in increased expression of CYP2D6 mRNA CTD PMID:27939613 NCBI chr 7:123,599,264...123,608,436
Ensembl chr 7:123,599,266...123,608,436
JBrowse link
G H CYP2D6 cytochrome P450 family 2 subfamily D member 6 increases expression EXP obeticholic acid results in increased expression of CYP2D6 mRNA CTD PMID:27939613 NCBI chr22:42,126,499...42,130,810
Ensembl chr22:42,126,499...42,130,881
Ensembl chr22:42,126,499...42,130,881
JBrowse link
G R Cyp2e1 cytochrome P450, family 2, subfamily e, polypeptide 1 decreases expression ISO obeticholic acid results in decreased expression of CYP2E1 mRNA CTD PMID:27939613 NCBI chr 1:213,511,892...213,522,195
Ensembl chr 1:213,511,874...213,535,542
JBrowse link
G M Cyp2e1 cytochrome P450, family 2, subfamily e, polypeptide 1 decreases expression ISO obeticholic acid results in decreased expression of CYP2E1 mRNA CTD PMID:27939613 NCBI chr 7:140,763,819...140,774,990
Ensembl chr 7:140,763,739...140,774,987
JBrowse link
G H CYP2E1 cytochrome P450 family 2 subfamily E member 1 decreases expression EXP obeticholic acid results in decreased expression of CYP2E1 mRNA CTD PMID:27939613 NCBI chr10:133,527,363...133,539,123
Ensembl chr10:133,520,406...133,561,220
JBrowse link
G R Cyp2r1 cytochrome P450, family 2, subfamily r, polypeptide 1 increases expression ISO obeticholic acid results in increased expression of CYP2R1 mRNA CTD PMID:27939613 NCBI chr 1:184,060,521...184,106,604
Ensembl chr 1:184,093,920...184,106,200
JBrowse link
G M Cyp2r1 cytochrome P450, family 2, subfamily r, polypeptide 1 increases expression ISO obeticholic acid results in increased expression of CYP2R1 mRNA CTD PMID:27939613 NCBI chr 7:114,550,123...114,563,048
Ensembl chr 7:114,549,682...114,562,972
JBrowse link
G H CYP2R1 cytochrome P450 family 2 subfamily R member 1 increases expression EXP obeticholic acid results in increased expression of CYP2R1 mRNA CTD PMID:27939613 NCBI chr11:14,877,440...14,898,915
Ensembl chr11:14,877,440...14,892,252
Ensembl chr11:14,877,440...14,892,252
JBrowse link
G R Cyp2s1 cytochrome P450, family 2, subfamily s, polypeptide 1 decreases expression ISO obeticholic acid results in decreased expression of CYP2S1 mRNA CTD PMID:27939613 NCBI chr 1:82,595,211...82,610,350
Ensembl chr 1:82,595,211...82,610,350
JBrowse link
G M Cyp2s1 cytochrome P450, family 2, subfamily s, polypeptide 1 decreases expression ISO obeticholic acid results in decreased expression of CYP2S1 mRNA CTD PMID:27939613 NCBI chr 7:25,802,469...25,816,525
Ensembl chr 7:25,802,475...25,816,913
JBrowse link
G H CYP2S1 cytochrome P450 family 2 subfamily S member 1 decreases expression EXP obeticholic acid results in decreased expression of CYP2S1 mRNA CTD PMID:27939613 NCBI chr19:41,193,219...41,207,539
Ensembl chr19:41,193,210...41,207,539
JBrowse link
G R Cyp2u1 cytochrome P450, family 2, subfamily u, polypeptide 1 increases expression ISO obeticholic acid results in increased expression of CYP2U1 mRNA CTD PMID:27939613 NCBI chr 2:236,414,131...236,431,650
Ensembl chr 2:236,414,135...236,431,683
JBrowse link
G M Cyp2u1 cytochrome P450, family 2, subfamily u, polypeptide 1 increases expression ISO obeticholic acid results in increased expression of CYP2U1 mRNA CTD PMID:27939613 NCBI chr 3:131,290,491...131,304,157
Ensembl chr 3:131,288,441...131,303,227
JBrowse link
G H CYP2U1 cytochrome P450 family 2 subfamily U member 1 increases expression EXP obeticholic acid results in increased expression of CYP2U1 mRNA CTD PMID:27939613 NCBI chr 4:107,931,549...107,953,461
Ensembl chr 4:107,931,549...107,953,461
JBrowse link
G R Cyp39a1 cytochrome P450, family 39, subfamily a, polypeptide 1 decreases expression ISO obeticholic acid results in decreased expression of CYP39A1 mRNA CTD PMID:27939613 NCBI chr 9:19,804,079...19,880,346
Ensembl chr 9:19,804,079...19,880,346
JBrowse link
G M Cyp39a1 cytochrome P450, family 39, subfamily a, polypeptide 1 decreases expression ISO obeticholic acid results in decreased expression of CYP39A1 mRNA CTD PMID:27939613 NCBI chr17:43,667,372...43,751,431
Ensembl chr17:43,667,425...43,751,431
JBrowse link
G H CYP39A1 cytochrome P450 family 39 subfamily A member 1 decreases expression EXP obeticholic acid results in decreased expression of CYP39A1 mRNA CTD PMID:27939613 NCBI chr 6:46,549,580...46,652,849
Ensembl chr 6:46,549,580...46,652,830
JBrowse link
G M Cyp3a13 cytochrome P450, family 3, subfamily a, polypeptide 13 decreases expression ISO obeticholic acid results in decreased expression of CYP3A5 mRNA CTD PMID:27939613 NCBI chr 5:137,892,933...137,925,610
Ensembl chr 5:137,892,932...137,921,619
JBrowse link
G R Cyp3a18 cytochrome P450, family 3, subfamily a, polypeptide 18 decreases expression ISO obeticholic acid results in decreased expression of CYP3A43 mRNA CTD PMID:27939613 NCBI chr12:10,636,294...10,684,273
Ensembl chr12:10,636,275...10,684,278
JBrowse link
G H CYP3A4 cytochrome P450 family 3 subfamily A member 4 decreases activity
decreases expression
multiple interactions
EXP obeticholic acid results in decreased activity of CYP3A4 protein
obeticholic acid results in decreased expression of CYP3A4 mRNA
obeticholic acid inhibits the reaction [CYP3A4 protein results in increased chemical synthesis of 6 beta-hydroxytestosterone]; obeticholic acid inhibits the reaction [CYP3A4 protein results in increased metabolism of Testosterone]
CTD PMID:27939613 NCBI chr 7:99,756,967...99,784,184
Ensembl chr 7:99,756,960...99,784,248
JBrowse link
G H CYP3A43 cytochrome P450 family 3 subfamily A member 43 decreases expression EXP obeticholic acid results in decreased expression of CYP3A43 mRNA CTD PMID:27939613 NCBI chr 7:99,827,626...99,867,138
Ensembl chr 7:99,828,013...99,866,102
JBrowse link
G H CYP3A5 cytochrome P450 family 3 subfamily A member 5 decreases expression EXP obeticholic acid results in decreased expression of CYP3A5 mRNA CTD PMID:27939613 NCBI chr 7:99,648,194...99,679,996
Ensembl chr 7:99,648,194...99,679,998
JBrowse link
G R Cyp3a62 cytochrome P450, family 3, subfamily a, polypeptide 62 decreases expression
decreases activity
multiple interactions
ISO obeticholic acid results in decreased expression of CYP3A4 mRNA
obeticholic acid results in decreased activity of CYP3A4 protein
obeticholic acid inhibits the reaction [CYP3A4 protein results in increased chemical synthesis of 6 beta-hydroxytestosterone]; obeticholic acid inhibits the reaction [CYP3A4 protein results in increased metabolism of Testosterone]
CTD PMID:27939613 NCBI chr12:18,679,809...18,709,397
Ensembl chr12:18,678,594...18,709,397
JBrowse link
G H CYP3A7 cytochrome P450 family 3 subfamily A member 7 decreases expression EXP obeticholic acid results in decreased expression of CYP3A7 mRNA CTD PMID:27939613 NCBI chr 7:99,705,036...99,735,196
Ensembl chr 7:99,705,036...99,735,196
Ensembl chr 7:99,705,036...99,735,196
JBrowse link
G R Cyp3a9 cytochrome P450, family 3, subfamily a, polypeptide 9 decreases expression ISO obeticholic acid results in decreased expression of CYP3A5 mRNA CTD PMID:27939613 NCBI chr12:19,074,288...19,114,491
Ensembl chr12:19,074,583...19,114,399
JBrowse link
G H CYP4A11 cytochrome P450 family 4 subfamily A member 11 increases expression EXP obeticholic acid results in increased expression of CYP4A11 mRNA CTD PMID:27939613 NCBI chr 1:46,929,177...46,941,476
Ensembl chr 1:46,929,177...46,941,484
JBrowse link
G M Cyp4a14 cytochrome P450, family 4, subfamily a, polypeptide 14 increases expression EXP obeticholic acid results in increased expression of CYP4A14 mRNA CTD PMID:26655953 NCBI chr 4:115,486,200...115,496,158
Ensembl chr 4:115,486,200...115,496,142
JBrowse link
G R Cyp4f1 cytochrome P450, family 4, subfamily f, polypeptide 1 decreases expression ISO obeticholic acid results in decreased expression of CYP4F12 mRNA CTD PMID:27939613 NCBI chr 7:15,179,472...15,191,113
Ensembl chr 7:15,179,467...15,190,796
JBrowse link
G H CYP4F11 cytochrome P450 family 4 subfamily F member 11 decreases expression EXP obeticholic acid results in decreased expression of CYP4F11 mRNA CTD PMID:27939613 NCBI chr19:15,912,377...15,934,867
Ensembl chr19:15,912,367...15,934,867
JBrowse link
G H CYP4F12 cytochrome P450 family 4 subfamily F member 12 decreases expression EXP obeticholic acid results in decreased expression of CYP4F12 mRNA CTD PMID:27939613 NCBI chr19:15,673,023...15,698,819
Ensembl chr19:15,673,018...15,697,174
JBrowse link
G M Cyp4f14 cytochrome P450, family 4, subfamily f, polypeptide 14 decreases expression ISO obeticholic acid results in decreased expression of CYP4F12 mRNA CTD PMID:27939613 NCBI chr17:32,903,357...32,917,376
Ensembl chr17:32,905,070...32,917,342
JBrowse link
G R Cyp4f18 cytochrome P450, family 4, subfamily f, polypeptide 18 decreases expression ISO obeticholic acid results in decreased expression of CYP4F3 mRNA CTD PMID:27939613 NCBI chr16:19,501,680...19,528,935
Ensembl chr16:19,410,810...19,528,999
JBrowse link
G M Cyp4f18 cytochrome P450, family 4, subfamily f, polypeptide 18 decreases expression ISO obeticholic acid results in decreased expression of CYP4F3 mRNA CTD PMID:27939613 NCBI chr 8:71,988,482...72,009,668
Ensembl chr 8:71,988,482...72,009,626
JBrowse link
G H CYP4F22 cytochrome P450 family 4 subfamily F member 22 decreases expression EXP obeticholic acid results in decreased expression of CYP4F22 mRNA CTD PMID:27939613 NCBI chr19:15,508,487...15,552,317
Ensembl chr19:15,508,525...15,552,317
JBrowse link
G H CYP4F3 cytochrome P450 family 4 subfamily F member 3 decreases expression EXP obeticholic acid results in decreased expression of CYP4F3 mRNA CTD PMID:27939613 NCBI chr19:15,640,897...15,662,825
Ensembl chr19:15,640,897...15,662,825
JBrowse link
G R Cyp4f39 cytochrome P450, family 4, subfamily f, polypeptide 39 decreases expression ISO obeticholic acid results in decreased expression of CYP4F22 mRNA CTD PMID:27939613 NCBI chr 7:14,435,024...14,514,960
Ensembl chr 7:14,441,476...14,515,212
JBrowse link
G M Cyp4f39 cytochrome P450, family 4, subfamily f, polypeptide 39 decreases expression ISO obeticholic acid results in decreased expression of CYP4F22 mRNA CTD PMID:27939613 NCBI chr17:32,452,697...32,493,320
Ensembl chr17:32,452,723...32,493,320
JBrowse link
G R Cyp4f40 cytochrome P450, family 4, subfamily f, polypeptide 40 decreases expression ISO obeticholic acid results in decreased expression of CYP4F11 mRNA CTD PMID:27939613 NCBI chr 7:14,865,941...14,880,084
Ensembl chr 7:14,865,941...14,880,084
JBrowse link
G R Cyp51 cytochrome P450, family 51 decreases expression ISO obeticholic acid results in decreased expression of CYP51A1 mRNA CTD PMID:27939613 NCBI chr 4:27,175,564...27,194,018
Ensembl chr 4:27,175,243...27,194,018
JBrowse link
G M Cyp51 cytochrome P450, family 51 decreases expression ISO obeticholic acid results in decreased expression of CYP51A1 mRNA CTD PMID:27939613 NCBI chr 5:4,080,674...4,104,697
Ensembl chr 5:4,081,145...4,104,746
JBrowse link
G H CYP51A1 cytochrome P450 family 51 subfamily A member 1 decreases expression EXP obeticholic acid results in decreased expression of CYP51A1 mRNA CTD PMID:27939613 NCBI chr 7:92,112,153...92,134,803
Ensembl chr 7:92,112,153...92,134,803
JBrowse link
G R Cyp7a1 cytochrome P450 family 7 subfamily A member 1 decreases expression
multiple interactions
ISO
EXP
obeticholic acid results in decreased expression of CYP7A1 mRNA
obeticholic acid inhibits the reaction [Isoniazid results in increased expression of CYP7A1 mRNA]
Obeticholic acid inhibits the reaction [ethanol increases expression of Cyp7a1 protein in liver]
obeticholic acid decreases expression of CYP7a1 mRNA in liver in porcine serum induced model of cirrhosis in rat
obeticholic acid promotes the reaction [1-Naphthylisothiocyanate results in decreased expression of CYP7A1 mRNA]
CTD PMID:15644430 PMID:15911693 PMID:27939613 PMID:29660435 PMID:32673658, PMID:27939985, PMID:15521018 RGD:15036816, RGD:15045602 NCBI chr 5:19,358,734...19,368,431
Ensembl chr 5:19,358,734...19,368,431
JBrowse link
G M Cyp7a1 cytochrome P450, family 7, subfamily a, polypeptide 1 decreases expression
multiple interactions
ISO
EXP
obeticholic acid results in decreased expression of CYP7A1 mRNA
obeticholic acid inhibits the reaction [Isoniazid results in increased expression of CYP7A1 mRNA]
Obeticholic acid inhibits the reaction [ethanol increases expression of Cyp7a1 protein in liver]
obeticholic acid decreases expression of CYP7a1 mRNA in liver in porcine serum induced model of cirrhosis in rat
obeticholic acid promotes the reaction [1-Naphthylisothiocyanate results in decreased expression of CYP7A1 mRNA]
CTD PMID:15644430 PMID:15911693 PMID:27939613 PMID:29660435 PMID:32673658, PMID:27939985, PMID:15521018 RGD:15036816, RGD:15045602 NCBI chr 4:6,265,612...6,275,632
Ensembl chr 4:6,265,612...6,275,633
JBrowse link
G H CYP7A1 cytochrome P450 family 7 subfamily A member 1 decreases expression
multiple interactions
EXP
ISO
obeticholic acid results in decreased expression of CYP7A1 mRNA
obeticholic acid inhibits the reaction [Isoniazid results in increased expression of CYP7A1 mRNA]
Obeticholic acid inhibits the reaction [ethanol increases expression of Cyp7a1 protein in liver]
obeticholic acid decreases expression of CYP7a1 mRNA in liver in porcine serum induced model of cirrhosis in rat
obeticholic acid promotes the reaction [1-Naphthylisothiocyanate results in decreased expression of CYP7A1 mRNA]
CTD PMID:15644430 PMID:15911693 PMID:27939613 PMID:29660435 PMID:32673658, PMID:27939985, PMID:15521018 RGD:15036816, RGD:15045602 NCBI chr 8:58,490,178...58,500,163
Ensembl chr 8:58,490,178...58,500,163
JBrowse link
G R Cyp8b1 cytochrome P450 family 8 subfamily B member 1 decreases expression
multiple interactions
increases expression
EXP
ISO
obeticholic acid results in decreased expression of CYP8B1 mRNA
obeticholic acid inhibits the reaction [1-Naphthylisothiocyanate results in decreased expression of CYP8B1 mRNA]
obeticholic acid results in increased expression of CYP8B1 mRNA
CTD PMID:15644430 PMID:27939613 PMID:29660435 NCBI chr 8:130,548,418...130,550,388
Ensembl chr 8:130,548,418...130,550,388
JBrowse link
G M Cyp8b1 cytochrome P450, family 8, subfamily b, polypeptide 1 decreases expression
multiple interactions
increases expression
ISO
EXP
obeticholic acid results in decreased expression of CYP8B1 mRNA
obeticholic acid inhibits the reaction [1-Naphthylisothiocyanate results in decreased expression of CYP8B1 mRNA]
obeticholic acid results in increased expression of CYP8B1 mRNA
CTD PMID:15644430 PMID:27939613 PMID:29660435 NCBI chr 9:121,914,356...121,916,305
Ensembl chr 9:121,914,356...121,916,305
JBrowse link
G H CYP8B1 cytochrome P450 family 8 subfamily B member 1 decreases expression
multiple interactions
increases expression
ISO
EXP
obeticholic acid results in decreased expression of CYP8B1 mRNA
obeticholic acid inhibits the reaction [1-Naphthylisothiocyanate results in decreased expression of CYP8B1 mRNA]
obeticholic acid results in increased expression of CYP8B1 mRNA
CTD PMID:15644430 PMID:27939613 PMID:29660435 NCBI chr 3:42,872,192...42,875,879
Ensembl chr 3:42,856,005...42,875,898
JBrowse link
G R Ddit3 DNA-damage inducible transcript 3 multiple interactions ISO obeticholic acid inhibits the reaction [Dietary Fats results in increased expression of DDIT3 protein] CTD PMID:26655953 NCBI chr 7:70,578,564...70,585,074
Ensembl chr 7:70,580,198...70,585,084
JBrowse link
G M Ddit3 DNA-damage inducible transcript 3 multiple interactions EXP obeticholic acid inhibits the reaction [Dietary Fats results in increased expression of DDIT3 protein] CTD PMID:26655953 NCBI chr10:127,290,793...127,296,291
Ensembl chr10:127,290,774...127,296,288
Ensembl chr10:127,290,774...127,296,288
JBrowse link
G H DDIT3 DNA damage inducible transcript 3 multiple interactions ISO obeticholic acid inhibits the reaction [Dietary Fats results in increased expression of DDIT3 protein] CTD PMID:26655953 NCBI chr12:57,516,588...57,520,517
Ensembl chr12:57,516,588...57,521,737
JBrowse link
G R Dgat2 diacylglycerol O-acyltransferase 2 decreases expression ISO obeticholic acid results in decreased expression of DGAT2 mRNA CTD PMID:27939613 NCBI chr 1:164,113,459...164,143,818
Ensembl chr 1:164,113,459...164,143,818
JBrowse link
G M Dgat2 diacylglycerol O-acyltransferase 2 decreases expression ISO obeticholic acid results in decreased expression of DGAT2 mRNA CTD PMID:27939613 NCBI chr 7:99,153,663...99,182,713
Ensembl chr 7:99,153,658...99,182,719
JBrowse link
G H DGAT2 diacylglycerol O-acyltransferase 2 decreases expression EXP obeticholic acid results in decreased expression of DGAT2 mRNA CTD PMID:27939613 NCBI chr11:75,768,778...75,801,534
Ensembl chr11:75,759,512...75,801,535
JBrowse link
G R Dhcr7 7-dehydrocholesterol reductase increases expression ISO obeticholic acid results in increased expression of DHCR7 mRNA CTD PMID:27939613 NCBI chr 1:217,018,916...217,034,890
Ensembl chr 1:217,018,916...217,034,904
JBrowse link
G M Dhcr7 7-dehydrocholesterol reductase increases expression ISO obeticholic acid results in increased expression of DHCR7 mRNA CTD PMID:27939613 NCBI chr 7:143,823,167...143,848,410
Ensembl chr 7:143,823,145...143,848,410
JBrowse link
G H DHCR7 7-dehydrocholesterol reductase increases expression EXP obeticholic acid results in increased expression of DHCR7 mRNA CTD PMID:27939613 NCBI chr11:71,434,411...71,448,393
Ensembl chr11:71,428,193...71,452,868
JBrowse link
G R Dnajb11 DnaJ heat shock protein family (Hsp40) member B11 increases expression ISO obeticholic acid results in increased expression of DNAJB11 mRNA CTD PMID:27939613 NCBI chr11:81,741,342...81,757,806
Ensembl chr11:81,741,297...81,757,813
JBrowse link
G M Dnajb11 DnaJ heat shock protein family (Hsp40) member B11 increases expression ISO obeticholic acid results in increased expression of DNAJB11 mRNA CTD PMID:27939613 NCBI chr16:22,857,845...22,879,634
Ensembl chr16:22,857,845...22,879,634
JBrowse link
G H DNAJB11 DnaJ heat shock protein family (Hsp40) member B11 increases expression EXP obeticholic acid results in increased expression of DNAJB11 mRNA CTD PMID:27939613 NCBI chr 3:186,570,720...186,585,793
Ensembl chr 3:186,567,403...186,585,800
JBrowse link
G R Dpyd dihydropyrimidine dehydrogenase decreases expression ISO obeticholic acid results in decreased expression of DPYD mRNA CTD PMID:27939613 NCBI chr 2:221,823,692...222,694,627
Ensembl chr 2:221,823,687...222,694,627
JBrowse link
G M Dpyd dihydropyrimidine dehydrogenase decreases expression ISO obeticholic acid results in decreased expression of DPYD mRNA CTD PMID:27939613 NCBI chr 3:118,562,109...119,432,924
Ensembl chr 3:118,562,129...119,432,924
JBrowse link
G H DPYD dihydropyrimidine dehydrogenase decreases expression EXP obeticholic acid results in decreased expression of DPYD mRNA CTD PMID:27939613 NCBI chr 1:97,077,743...97,921,059
Ensembl chr 1:97,077,743...97,995,000
JBrowse link
G R Dusp6 dual specificity phosphatase 6 increases expression ISO obeticholic acid results in increased expression of DUSP6 mRNA CTD PMID:27939613 NCBI chr 7:41,475,163...41,479,393
Ensembl chr 7:41,475,163...41,479,392
JBrowse link
G M Dusp6 dual specificity phosphatase 6 increases expression ISO obeticholic acid results in increased expression of DUSP6 mRNA CTD PMID:27939613 NCBI chr10:99,263,231...99,267,489
Ensembl chr10:99,263,231...99,267,489
JBrowse link
G H DUSP6 dual specificity phosphatase 6 increases expression EXP obeticholic acid results in increased expression of DUSP6 mRNA CTD PMID:27939613 NCBI chr12:89,347,235...89,352,501
Ensembl chr12:89,347,235...89,352,501
JBrowse link
G R Ecsit ECSIT signaling integrator decreases expression ISO obeticholic acid results in decreased expression of ECSIT mRNA CTD PMID:27939613 NCBI chr 8:23,085,598...23,099,064
Ensembl chr 8:23,085,590...23,099,042
JBrowse link
G M Ecsit ECSIT signalling integrator decreases expression ISO obeticholic acid results in decreased expression of ECSIT mRNA CTD PMID:27939613 NCBI chr 9:22,071,435...22,086,296
Ensembl chr 9:22,072,246...22,085,438
JBrowse link
G H ECSIT ECSIT signaling integrator decreases expression EXP obeticholic acid results in decreased expression of ECSIT mRNA CTD PMID:27939613 NCBI chr19:11,505,929...11,529,134
Ensembl chr19:11,505,929...11,529,172
JBrowse link
G R Elovl1 ELOVL fatty acid elongase 1 increases expression ISO obeticholic acid results in increased expression of ELOVL1 mRNA CTD PMID:27939613 NCBI chr 5:137,255,868...137,260,486
Ensembl chr 5:137,255,908...137,260,483
JBrowse link
G M Elovl1 elongation of very long chain fatty acids (FEN1/Elo2, SUR4/Elo3, yeast)-like 1 increases expression ISO obeticholic acid results in increased expression of ELOVL1 mRNA CTD PMID:27939613 NCBI chr 4:118,426,874...118,432,953
Ensembl chr 4:118,428,093...118,432,953
JBrowse link
G H ELOVL1 ELOVL fatty acid elongase 1 increases expression EXP obeticholic acid results in increased expression of ELOVL1 mRNA CTD PMID:27939613 NCBI chr 1:43,363,401...43,368,011
Ensembl chr 1:43,363,398...43,368,074
JBrowse link
G R Elovl2 ELOVL fatty acid elongase 2 increases expression ISO obeticholic acid results in increased expression of ELOVL2 mRNA CTD PMID:27939613 NCBI chr17:21,382,461...21,422,413
Ensembl chr17:21,382,455...21,422,407
JBrowse link
G M Elovl2 elongation of very long chain fatty acids (FEN1/Elo2, SUR4/Elo3, yeast)-like 2 increases expression ISO obeticholic acid results in increased expression of ELOVL2 mRNA CTD PMID:27939613 NCBI chr13:41,182,382...41,220,403
Ensembl chr13:41,182,381...41,220,405
JBrowse link
G H ELOVL2 ELOVL fatty acid elongase 2 increases expression EXP obeticholic acid results in increased expression of ELOVL2 mRNA CTD PMID:27939613 NCBI chr 6:10,980,759...11,044,305
Ensembl chr 6:10,980,759...11,044,305
JBrowse link
G R Elovl6 ELOVL fatty acid elongase 6 decreases expression ISO obeticholic acid results in decreased expression of ELOVL6 mRNA CTD PMID:27939613 NCBI chr 2:234,187,490...234,296,124
Ensembl chr 2:234,189,105...234,296,145
Ensembl chr 2:234,189,105...234,296,145
JBrowse link
G M Elovl6 ELOVL family member 6, elongation of long chain fatty acids (yeast) decreases expression ISO obeticholic acid results in decreased expression of ELOVL6 mRNA CTD PMID:27939613 NCBI chr 3:129,532,386...129,638,495
Ensembl chr 3:129,532,355...129,638,495
JBrowse link
G H ELOVL6 ELOVL fatty acid elongase 6 decreases expression EXP obeticholic acid results in decreased expression of ELOVL6 mRNA CTD PMID:27939613 NCBI chr 4:110,045,846...110,199,199
Ensembl chr 4:110,045,846...110,199,199
JBrowse link
G R Elovl7 ELOVL fatty acid elongase 7 increases expression ISO obeticholic acid results in increased expression of ELOVL7 mRNA CTD PMID:27939613 NCBI chr 2:40,373,211...40,386,643
Ensembl chr 2:40,373,211...40,386,669
JBrowse link
G M Elovl7 ELOVL family member 7, elongation of long chain fatty acids (yeast) increases expression ISO obeticholic acid results in increased expression of ELOVL7 mRNA CTD PMID:27939613 NCBI chr13:108,214,326...108,287,109
Ensembl chr13:108,214,404...108,285,683
JBrowse link
G H ELOVL7 ELOVL fatty acid elongase 7 increases expression EXP obeticholic acid results in increased expression of ELOVL7 mRNA CTD PMID:27939613 NCBI chr 5:60,751,791...60,844,292
Ensembl chr 5:60,751,791...60,844,274
JBrowse link
G R Enc1 ectodermal-neural cortex 1 increases expression ISO obeticholic acid results in increased expression of ENC1 mRNA CTD PMID:27939613 NCBI chr 2:28,049,217...28,061,023
Ensembl chr 2:28,049,217...28,061,029
JBrowse link
G M Enc1 ectodermal-neural cortex 1 increases expression ISO obeticholic acid results in increased expression of ENC1 mRNA CTD PMID:27939613 NCBI chr13:97,241,105...97,253,040
Ensembl chr13:97,241,105...97,253,034
JBrowse link
G H ENC1 ectodermal-neural cortex 1 increases expression EXP obeticholic acid results in increased expression of ENC1 mRNA CTD PMID:27939613 NCBI chr 5:74,627,409...74,640,728
Ensembl chr 5:74,627,406...74,641,424
JBrowse link
G R Eno1 enolase 1 decreases expression ISO obeticholic acid results in decreased expression of ENO1 mRNA CTD PMID:27939613 NCBI chr 5:167,288,223...167,299,610
Ensembl chr 5:167,288,223...167,299,609
JBrowse link
G M Eno1 enolase 1, alpha non-neuron decreases expression ISO obeticholic acid results in decreased expression of ENO1 mRNA CTD PMID:27939613 NCBI chr 4:150,236,708...150,248,879
Ensembl chr 4:150,236,721...150,248,879
JBrowse link
G H ENO1 enolase 1 decreases expression EXP obeticholic acid results in decreased expression of ENO1 mRNA CTD PMID:27939613 NCBI chr 1:8,861,000...8,878,686
Ensembl chr 1:8,861,000...8,879,190
JBrowse link
G R Eno3 enolase 3 increases expression ISO obeticholic acid results in increased expression of ENO3 mRNA CTD PMID:27939613 NCBI chr10:57,278,271...57,283,661
Ensembl chr10:57,278,307...57,283,653
JBrowse link
G M Eno3 enolase 3, beta muscle increases expression ISO obeticholic acid results in increased expression of ENO3 mRNA CTD PMID:27939613 NCBI chr11:70,653,125...70,662,513
Ensembl chr11:70,657,202...70,662,513
JBrowse link
G H ENO3 enolase 3 increases expression EXP obeticholic acid results in increased expression of ENO3 mRNA CTD PMID:27939613 NCBI chr17:4,949,182...4,957,131
Ensembl chr17:4,948,092...4,957,131
JBrowse link
G R Fabp6 fatty acid binding protein 6 multiple interactions
increases expression
ISO NR1H4 gene mutant form inhibits the reaction [obeticholic acid results in increased expression of FABP6 mRNA] CTD PMID:22918042 NCBI chr10:29,191,621...29,196,593
Ensembl chr10:29,191,623...29,196,563
JBrowse link
G M Fabp6 fatty acid binding protein 6 multiple interactions
increases expression
EXP NR1H4 gene mutant form inhibits the reaction [obeticholic acid results in increased expression of FABP6 mRNA] CTD PMID:22918042 NCBI chr11:43,596,040...43,601,562
Ensembl chr11:43,596,049...43,601,540
JBrowse link
G H FABP6 fatty acid binding protein 6 multiple interactions
increases expression
ISO NR1H4 gene mutant form inhibits the reaction [obeticholic acid results in increased expression of FABP6 mRNA] CTD PMID:22918042 NCBI chr 5:160,187,381...160,238,722
Ensembl chr 5:160,187,367...160,238,735
JBrowse link
G R Fadd Fas associated via death domain increases expression ISO obeticholic acid results in increased expression of FADD mRNA CTD PMID:27939613 NCBI chr 1:217,746,176...217,748,581
Ensembl chr 1:217,742,929...217,748,628
JBrowse link
G M Fadd Fas (TNFRSF6)-associated via death domain increases expression ISO obeticholic acid results in increased expression of FADD mRNA CTD PMID:27939613 NCBI chr 7:144,578,323...144,582,441
Ensembl chr 7:144,577,318...144,582,463
JBrowse link
G H FADD Fas associated via death domain increases expression EXP obeticholic acid results in increased expression of FADD mRNA CTD PMID:27939613 NCBI chr11:70,203,296...70,207,390
Ensembl chr11:70,203,163...70,207,390
Ensembl chr11:70,203,163...70,207,390
JBrowse link
G R Fas Fas cell surface death receptor multiple interactions EXP Obeticholic acid inhibits the reaction [ethanol increases expression of Fas mRNA and protein in liver] RGD PMID:27939985 RGD:15036816 NCBI chr 1:252,589,785...252,624,790
Ensembl chr 1:252,589,785...252,624,790
JBrowse link
G M Fas Fas (TNF receptor superfamily member 6) multiple interactions ISO Obeticholic acid inhibits the reaction [ethanol increases expression of Fas mRNA and protein in liver] RGD PMID:27939985 RGD:15036816 NCBI chr19:34,290,647...34,327,775
Ensembl chr19:34,290,666...34,327,772
JBrowse link
G H FAS Fas cell surface death receptor multiple interactions ISO Obeticholic acid inhibits the reaction [ethanol increases expression of Fas mRNA and protein in liver] RGD PMID:27939985 RGD:15036816 NCBI chr10:88,968,429...89,017,059
Ensembl chr10:88,990,531...89,017,059
JBrowse link
G R Fasn fatty acid synthase multiple interactions
decreases expression
ISO obeticholic acid inhibits the reaction [Palmitic Acid results in increased expression of FASN mRNA]
obeticholic acid inhibits the reaction [Ethanol results in increased expression of FASN protein]
obeticholic acid results in decreased expression of FASN mRNA
CTD PMID:26655953 PMID:27939613 PMID:27939985 NCBI chr10:109,987,735...110,005,901
Ensembl chr10:109,987,735...110,005,901
JBrowse link
G M Fasn fatty acid synthase multiple interactions
decreases expression
EXP
ISO
obeticholic acid inhibits the reaction [Palmitic Acid results in increased expression of FASN mRNA]
obeticholic acid results in decreased expression of FASN mRNA
obeticholic acid inhibits the reaction [Ethanol results in increased expression of FASN protein]
CTD PMID:26655953 PMID:27939613 PMID:27939985 NCBI chr11:120,805,958...120,825,166
Ensembl chr11:120,805,846...120,824,547
JBrowse link
G H FASN fatty acid synthase multiple interactions
decreases expression
ISO
EXP
obeticholic acid inhibits the reaction [Palmitic Acid results in increased expression of FASN mRNA]
obeticholic acid inhibits the reaction [Ethanol results in increased expression of FASN protein]
obeticholic acid results in decreased expression of FASN mRNA
CTD PMID:26655953 PMID:27939613 PMID:27939985 NCBI chr17:82,078,338...82,098,303
Ensembl chr17:82,078,338...82,098,294
JBrowse link
G R Fbp1 fructose-bisphosphatase 1 decreases expression ISO obeticholic acid results in decreased expression of FBP1 mRNA CTD PMID:27939613 NCBI chr17:396,175...417,480
Ensembl chr17:396,180...417,480
JBrowse link
G M Fbp1 fructose bisphosphatase 1 decreases expression ISO obeticholic acid results in decreased expression of FBP1 mRNA CTD PMID:27939613 NCBI chr13:62,864,753...62,888,298
Ensembl chr13:62,864,753...62,888,282
JBrowse link
G H FBP1 fructose-bisphosphatase 1 decreases expression EXP obeticholic acid results in decreased expression of FBP1 mRNA CTD PMID:27939613 NCBI chr 9:94,603,133...94,640,263
Ensembl chr 9:94,603,133...94,640,249
JBrowse link
G R Fdps farnesyl diphosphate synthase decreases expression ISO obeticholic acid results in decreased expression of FDPS mRNA CTD PMID:27939613 NCBI chr 2:188,403,595...188,413,219
Ensembl chr 2:188,392,858...188,413,219
JBrowse link
G M Fdps farnesyl diphosphate synthetase decreases expression ISO obeticholic acid results in decreased expression of FDPS mRNA CTD PMID:27939613 NCBI chr 3:89,093,588...89,101,967
Ensembl chr 3:89,093,588...89,101,959
JBrowse link
G H FDPS farnesyl diphosphate synthase decreases expression EXP obeticholic acid results in decreased expression of FDPS mRNA CTD PMID:27939613 NCBI chr 1:155,308,801...155,320,665
Ensembl chr 1:155,308,748...155,320,666
JBrowse link
G R Fetub fetuin B increases expression ISO obeticholic acid results in increased expression of FETUB mRNA CTD PMID:27939613 NCBI chr11:81,648,890...81,660,472
Ensembl chr11:81,648,885...81,660,395
JBrowse link
G M Fetub fetuin beta increases expression ISO obeticholic acid results in increased expression of FETUB mRNA CTD PMID:27939613 NCBI chr16:22,918,382...22,939,768
Ensembl chr16:22,918,334...22,939,778
JBrowse link
G H FETUB fetuin B increases expression EXP obeticholic acid results in increased expression of FETUB mRNA CTD PMID:27939613 NCBI chr 3:186,635,969...186,653,141
Ensembl chr 3:186,635,969...186,653,141
JBrowse link
G M Fgf15 fibroblast growth factor 15 increases expression
multiple interactions
increases secretion
EXP
ISO
obeticholic acid results in increased expression of FGF15 mRNA
Obeticholic acid inhibits the reaction [ethanol decreases expression of FGF19 protein in liver and intestine]
obeticholic acid results in increased expression of FGF19 mRNA
obeticholic acid results in increased secretion of FGF19 protein
NR1H4 gene mutant form inhibits the reaction [obeticholic acid results in increased expression of FGF15 mRNA]
CTD PMID:22918042 PMID:27939613, PMID:27939985 RGD:15036816 NCBI chr 7:144,896,532...144,900,953
Ensembl chr 7:144,896,531...144,900,953
JBrowse link
G R Fgf19 fibroblast growth factor 19 increases expression
multiple interactions
increases secretion
ISO
EXP
obeticholic acid results in increased expression of FGF15 mRNA
Obeticholic acid inhibits the reaction [ethanol decreases expression of FGF19 protein in liver and intestine]
obeticholic acid results in increased secretion of FGF19 protein
obeticholic acid results in increased expression of FGF19 mRNA
NR1H4 gene mutant form inhibits the reaction [obeticholic acid results in increased expression of FGF15 mRNA]
CTD PMID:22918042 PMID:27939613, PMID:27939985 RGD:15036816 NCBI chr 1:218,058,405...218,061,693
Ensembl chr 1:218,058,405...218,061,693
JBrowse link
G H FGF19 fibroblast growth factor 19 increases expression
multiple interactions
increases secretion
ISO
EXP
obeticholic acid results in increased expression of FGF15 mRNA
Obeticholic acid inhibits the reaction [ethanol decreases expression of FGF19 protein in liver and intestine]
obeticholic acid results in increased expression of FGF19 mRNA
obeticholic acid results in increased secretion of FGF19 protein
NR1H4 gene mutant form inhibits the reaction [obeticholic acid results in increased expression of FGF15 mRNA]
CTD PMID:22918042 PMID:27939613, PMID:27939985 RGD:15036816 NCBI chr11:69,698,238...69,704,022
Ensembl chr11:69,698,238...69,704,022
JBrowse link
G R Fgfr4 fibroblast growth factor receptor 4 decreases expression ISO obeticholic acid results in decreased expression of FGFR4 mRNA CTD PMID:27939613 NCBI chr17:9,990,072...10,004,339
Ensembl chr17:9,990,078...10,004,321
JBrowse link
G M Fgfr4 fibroblast growth factor receptor 4 decreases expression ISO obeticholic acid results in decreased expression of FGFR4 mRNA CTD PMID:27939613 NCBI chr13:55,152,818...55,168,759
Ensembl chr13:55,152,640...55,168,759
JBrowse link
G H FGFR4 fibroblast growth factor receptor 4 decreases expression EXP obeticholic acid results in decreased expression of FGFR4 mRNA CTD PMID:27939613 NCBI chr 5:177,086,915...177,098,144
Ensembl chr 5:177,086,905...177,098,144
JBrowse link
G R Fn1 fibronectin 1 decreases expression EXP obeticholic acid decreases expression of fibronectin mRNA in liver in porcine serum induced model of cirrhosis in rat RGD PMID:15980055 RGD:1625201 NCBI chr 9:78,900,111...78,969,018
Ensembl chr 9:78,900,103...78,969,078
JBrowse link
G M Fn1 fibronectin 1 decreases expression ISO obeticholic acid decreases expression of fibronectin mRNA in liver in porcine serum induced model of cirrhosis in rat RGD PMID:15980055 RGD:1625201 NCBI chr 1:71,585,473...71,653,280
Ensembl chr 1:71,585,520...71,653,200
JBrowse link
G H FN1 fibronectin 1 decreases expression ISO obeticholic acid decreases expression of fibronectin mRNA in liver in porcine serum induced model of cirrhosis in rat RGD PMID:15980055 RGD:1625201 NCBI chr 2:215,360,862...215,436,167
Ensembl chr 2:215,360,440...215,436,073
JBrowse link
G R Fos Fos proto-oncogene, AP-1 transcription factor subunit decreases expression ISO obeticholic acid results in decreased expression of FOS mRNA CTD PMID:27939613 NCBI chr 6:109,300,433...109,303,299
Ensembl chr 6:109,300,433...109,303,299
JBrowse link
G M Fos FBJ osteosarcoma oncogene decreases expression ISO obeticholic acid results in decreased expression of FOS mRNA CTD PMID:27939613 NCBI chr12:85,473,890...85,477,274
Ensembl chr12:85,473,890...85,477,273
JBrowse link
G H FOS Fos proto-oncogene, AP-1 transcription factor subunit decreases expression EXP obeticholic acid results in decreased expression of FOS mRNA CTD PMID:27939613 NCBI chr14:75,278,828...75,282,230
Ensembl chr14:75,278,826...75,282,230
JBrowse link
G R Foxm1 forkhead box M1 multiple interactions
increases expression
ISO NR1H4 affects the reaction [obeticholic acid results in increased expression of FOXM1 mRNA]; obeticholic acid promotes the reaction [1-Naphthylisothiocyanate results in increased expression of FOXM1 protein] CTD PMID:22135065 PMID:29660435 NCBI chr 4:161,685,236...161,697,633
Ensembl chr 4:161,685,258...161,696,305
JBrowse link
G M Foxm1 forkhead box M1 multiple interactions
increases expression
EXP NR1H4 affects the reaction [obeticholic acid results in increased expression of FOXM1 mRNA]; obeticholic acid promotes the reaction [1-Naphthylisothiocyanate results in increased expression of FOXM1 protein] CTD PMID:22135065 PMID:29660435 NCBI chr 6:128,362,994...128,375,886
Ensembl chr 6:128,362,967...128,376,146
JBrowse link
G H FOXM1 forkhead box M1 multiple interactions
increases expression
ISO NR1H4 affects the reaction [obeticholic acid results in increased expression of FOXM1 mRNA]; obeticholic acid promotes the reaction [1-Naphthylisothiocyanate results in increased expression of FOXM1 protein] CTD PMID:22135065 PMID:29660435 NCBI chr12:2,857,680...2,877,174
Ensembl chr12:2,857,681...2,877,155
Ensembl chr12:2,857,681...2,877,155
JBrowse link
G R Foxp3 forkhead box P3 increases expression ISO obeticholic acid results in increased expression of FOXP3 mRNA CTD PMID:27939613 NCBI chr  X:15,753,175...15,768,648
Ensembl chr  X:15,753,175...15,768,522
JBrowse link
G M Foxp3 forkhead box P3 increases expression ISO obeticholic acid results in increased expression of FOXP3 mRNA CTD PMID:27939613 NCBI chr  X:7,579,676...7,595,243
Ensembl chr  X:7,573,644...7,595,245
JBrowse link
G H FOXP3 forkhead box P3 increases expression EXP obeticholic acid results in increased expression of FOXP3 mRNA CTD PMID:27939613 NCBI chr  X:49,250,436...49,264,932
Ensembl chr  X:49,250,438...49,270,477
Ensembl chr  X:49,250,438...49,270,477
JBrowse link
G R Gapdh glyceraldehyde-3-phosphate dehydrogenase decreases expression ISO obeticholic acid results in decreased expression of GAPDH mRNA CTD PMID:27939613 NCBI chr 4:157,676,336...157,680,322
Ensembl chr 4:157,676,595...157,679,962
JBrowse link
G M Gapdh glyceraldehyde-3-phosphate dehydrogenase decreases expression ISO obeticholic acid results in decreased expression of GAPDH mRNA CTD PMID:27939613 NCBI chr 6:125,161,852...125,166,467
Ensembl chr 6:125,161,715...125,166,467
JBrowse link
G H GAPDH glyceraldehyde-3-phosphate dehydrogenase decreases expression EXP obeticholic acid results in decreased expression of GAPDH mRNA CTD PMID:27939613 NCBI chr12:6,534,517...6,538,371
Ensembl chr12:6,534,512...6,538,374
JBrowse link
G R Gclm glutamate cysteine ligase, modifier subunit increases expression ISO obeticholic acid results in increased expression of GCLM mRNA CTD PMID:26655953 NCBI chr 2:225,827,504...225,847,876
Ensembl chr 2:225,827,504...225,847,874
JBrowse link
G M Gclm glutamate-cysteine ligase, modifier subunit increases expression EXP obeticholic acid results in increased expression of GCLM mRNA CTD PMID:26655953 NCBI chr 3:122,245,487...122,267,215
Ensembl chr 3:122,245,557...122,270,732
JBrowse link
G H GCLM glutamate-cysteine ligase modifier subunit increases expression ISO obeticholic acid results in increased expression of GCLM mRNA CTD PMID:26655953 NCBI chr 1:93,885,199...93,910,370
Ensembl chr 1:93,885,199...93,909,456
JBrowse link
G R Gk glycerol kinase decreases expression ISO obeticholic acid results in decreased expression of GK mRNA CTD PMID:27939613 NCBI chr  X:54,227,291...54,303,897
Ensembl chr  X:54,227,397...54,303,864
JBrowse link
G M Gk glycerol kinase decreases expression ISO obeticholic acid results in decreased expression of GK mRNA CTD PMID:27939613 NCBI chr  X:85,701,937...85,776,819
Ensembl chr  X:85,701,937...85,776,819
JBrowse link
G H GK glycerol kinase decreases expression EXP obeticholic acid results in decreased expression of GK mRNA CTD PMID:27939613 NCBI chr  X:30,653,348...30,731,462
Ensembl chr  X:30,653,359...30,731,456
Ensembl chr  X:30,653,359...30,731,456
JBrowse link
G R Gpam glycerol-3-phosphate acyltransferase, mitochondrial decreases expression ISO obeticholic acid results in decreased expression of GPAM mRNA CTD PMID:27939613 NCBI chr 1:275,843,823...275,906,880
Ensembl chr 1:275,846,819...275,906,686
JBrowse link
G M Gpam glycerol-3-phosphate acyltransferase, mitochondrial decreases expression ISO obeticholic acid results in decreased expression of GPAM mRNA CTD PMID:27939613 NCBI chr19:55,067,635...55,127,319
Ensembl chr19:55,067,268...55,127,238
JBrowse link
G H GPAM glycerol-3-phosphate acyltransferase, mitochondrial decreases expression EXP obeticholic acid results in decreased expression of GPAM mRNA CTD PMID:27939613 NCBI chr10:112,149,865...112,216,306
Ensembl chr10:112,149,865...112,215,377
JBrowse link
G R Gpd1 glycerol-3-phosphate dehydrogenase 1 decreases expression ISO obeticholic acid results in decreased expression of GPD1 mRNA CTD PMID:27939613 NCBI chr 7:141,368,928...141,377,931
Ensembl chr 7:141,370,491...141,377,928
JBrowse link
G M Gpd1 glycerol-3-phosphate dehydrogenase 1 (soluble) decreases expression ISO obeticholic acid results in decreased expression of GPD1 mRNA CTD PMID:27939613 NCBI chr15:99,717,587...99,725,014
Ensembl chr15:99,717,515...99,725,005
JBrowse link
G H GPD1 glycerol-3-phosphate dehydrogenase 1 decreases expression EXP obeticholic acid results in decreased expression of GPD1 mRNA CTD PMID:27939613 NCBI chr12:50,104,008...50,111,313
Ensembl chr12:50,103,982...50,111,313
JBrowse link
G R Gpx1 glutathione peroxidase 1 increases expression ISO obeticholic acid results in increased expression of GPX1 mRNA CTD PMID:26655953 NCBI chr 8:117,117,430...117,118,528
Ensembl chr 8:117,117,430...117,118,522
JBrowse link
G M Gpx1 glutathione peroxidase 1 increases expression EXP obeticholic acid results in increased expression of GPX1 mRNA CTD PMID:26655953 NCBI chr 9:108,339,080...108,340,342
Ensembl chr 9:108,338,903...108,340,343
JBrowse link
G H GPX1 glutathione peroxidase 1 increases expression ISO obeticholic acid results in increased expression of GPX1 mRNA CTD PMID:26655953 NCBI chr 3:49,357,176...49,358,353
Ensembl chr 3:49,357,176...49,358,358
Ensembl chr 3:49,357,176...49,358,358
JBrowse link
G R Gpx2 glutathione peroxidase 2 decreases expression ISO obeticholic acid results in decreased expression of GPX2 mRNA CTD PMID:27939613 NCBI chr 6:99,839,960...99,843,245
Ensembl chr 6:99,839,960...99,843,245
JBrowse link
G M Gpx2 glutathione peroxidase 2 decreases expression ISO obeticholic acid results in decreased expression of GPX2 mRNA CTD PMID:27939613 NCBI chr12:76,792,335...76,795,554
Ensembl chr12:76,792,333...76,795,554
JBrowse link
G H GPX2 glutathione peroxidase 2 decreases expression EXP obeticholic acid results in decreased expression of GPX2 mRNA CTD PMID:27939613 NCBI chr14:64,939,158...64,942,745
Ensembl chr14:64,939,152...64,942,905
JBrowse link
G R Gpx3 glutathione peroxidase 3 increases expression ISO obeticholic acid results in increased expression of GPX3 mRNA CTD PMID:27939613 NCBI chr10:40,247,436...40,255,423
Ensembl chr10:40,247,436...40,255,422
JBrowse link
G M Gpx3 glutathione peroxidase 3 increases expression ISO obeticholic acid results in increased expression of GPX3 mRNA CTD PMID:27939613 NCBI chr11:54,902,854...54,910,387
Ensembl chr11:54,902,453...54,910,377
JBrowse link
G H GPX3 glutathione peroxidase 3 increases expression EXP obeticholic acid results in increased expression of GPX3 mRNA CTD PMID:27939613 NCBI chr 5:151,020,591...151,028,988
Ensembl chr 5:151,020,438...151,028,992
JBrowse link
G R Gsr glutathione-disulfide reductase increases expression ISO obeticholic acid results in increased expression of GSR mRNA CTD PMID:26655953 PMID:27939613 NCBI chr16:62,197,617...62,239,987
Ensembl chr16:62,197,617...62,241,361
JBrowse link
G M Gsr glutathione reductase increases expression EXP
ISO
obeticholic acid results in increased expression of GSR mRNA CTD PMID:26655953 PMID:27939613 NCBI chr 8:33,653,238...33,698,162
Ensembl chr 8:33,652,523...33,698,163
JBrowse link
G H GSR glutathione-disulfide reductase increases expression ISO
EXP
obeticholic acid results in increased expression of GSR mRNA CTD PMID:26655953 PMID:27939613 NCBI chr 8:30,678,066...30,727,846
Ensembl chr 8:30,678,066...30,727,846
JBrowse link
G R Gstp1 glutathione S-transferase pi 1 decreases expression ISO obeticholic acid results in decreased expression of GSTP1 mRNA CTD PMID:27939613 NCBI chr 1:219,291,679...219,294,147
Ensembl chr 1:219,291,679...219,294,147
JBrowse link
G M Gstp1 glutathione S-transferase, pi 1 decreases expression ISO obeticholic acid results in decreased expression of GSTP1 mRNA CTD PMID:27939613 NCBI chr19:4,035,411...4,037,912
Ensembl chr19:4,035,407...4,037,985
JBrowse link
G H GSTP1 glutathione S-transferase pi 1 decreases expression EXP obeticholic acid results in decreased expression of GSTP1 mRNA CTD PMID:27939613 NCBI chr11:67,583,812...67,586,653
Ensembl chr11:67,583,742...67,586,656
Ensembl chr11:67,583,742...67,586,656
JBrowse link
G R Gstt1 glutathione S-transferase theta 1 increases expression ISO obeticholic acid results in increased expression of GSTT1 mRNA CTD PMID:27939613 NCBI chr20:13,799,102...13,816,527
Ensembl chr20:13,799,102...13,816,526
JBrowse link
G M Gstt1 glutathione S-transferase, theta 1 increases expression ISO obeticholic acid results in increased expression of GSTT1 mRNA CTD PMID:27939613 NCBI chr10:75,783,813...75,798,584
Ensembl chr10:75,783,813...75,798,584
JBrowse link
G H GSTT1 glutathione S-transferase theta 1 increases expression EXP obeticholic acid results in increased expression of GSTT1 mRNA CTD PMID:27939613
G R Gys2 glycogen synthase 2 increases expression ISO obeticholic acid results in increased expression of GYS2 mRNA CTD PMID:27939613 NCBI chr 4:176,638,632...176,679,805
Ensembl chr 4:176,638,629...176,679,815
JBrowse link
G M Gys2 glycogen synthase 2 increases expression ISO obeticholic acid results in increased expression of GYS2 mRNA CTD PMID:27939613 NCBI chr 6:142,422,612...142,473,130
Ensembl chr 6:142,422,613...142,473,109
JBrowse link
G H GYS2 glycogen synthase 2 increases expression EXP obeticholic acid results in increased expression of GYS2 mRNA CTD PMID:27939613 NCBI chr12:21,531,527...21,604,858
Ensembl chr12:21,536,107...21,604,847
JBrowse link
G H H2BC11 H2B clustered histone 11 decreases expression EXP obeticholic acid results in decreased expression of H2BC11 mRNA CTD PMID:27939613 NCBI chr 6:27,132,316...27,132,795
Ensembl chr 6:27,125,897...27,132,750
Ensembl chr 6:27,125,897...27,132,750
JBrowse link
G M H2bc21 H2B clustered histone 21 decreases expression ISO obeticholic acid results in decreased expression of H2BC11 mRNA CTD PMID:27939613 NCBI chr 3:96,221,072...96,223,738
Ensembl chr 3:96,221,119...96,223,738
JBrowse link
G R Hist2h2be histone cluster 2 H2B family member E decreases expression ISO obeticholic acid results in decreased expression of H2BC11 mRNA CTD PMID:27939613 NCBI chr 2:198,360,837...198,363,399
Ensembl chr 2:198,360,998...198,361,378
JBrowse link
G R Hmgcr 3-hydroxy-3-methylglutaryl-CoA reductase decreases expression ISO obeticholic acid results in decreased expression of HMGCR mRNA CTD PMID:27939613 NCBI chr 2:27,480,224...27,500,654
Ensembl chr 2:27,480,226...27,500,654
JBrowse link
G M Hmgcr 3-hydroxy-3-methylglutaryl-Coenzyme A reductase decreases expression ISO obeticholic acid results in decreased expression of HMGCR mRNA CTD PMID:27939613 NCBI chr13:96,648,962...96,670,936
Ensembl chr13:96,648,967...96,670,936
JBrowse link
G H HMGCR 3-hydroxy-3-methylglutaryl-CoA reductase decreases expression EXP obeticholic acid results in decreased expression of HMGCR mRNA CTD PMID:27939613 NCBI chr 5:75,336,334...75,362,116
Ensembl chr 5:75,336,329...75,362,101
Ensembl chr 5:75,336,329...75,362,101
JBrowse link
G R Hmgcs1 3-hydroxy-3-methylglutaryl-CoA synthase 1 decreases expression ISO obeticholic acid results in decreased expression of HMGCS1 mRNA CTD PMID:27939613 NCBI chr 2:52,427,351...52,445,082
Ensembl chr 2:52,431,601...52,445,055
JBrowse link
G M Hmgcs1 3-hydroxy-3-methylglutaryl-Coenzyme A synthase 1 decreases expression ISO obeticholic acid results in decreased expression of HMGCS1 mRNA CTD PMID:27939613 NCBI chr13:119,690,351...119,708,260
Ensembl chr13:119,690,379...119,708,260
JBrowse link
G H HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 decreases expression EXP obeticholic acid results in decreased expression of HMGCS1 mRNA CTD PMID:27939613 NCBI chr 5:43,287,470...43,313,477
Ensembl chr 5:43,287,470...43,313,512
JBrowse link
G R Hras HRas proto-oncogene, GTPase decreases expression ISO obeticholic acid results in decreased expression of HRAS mRNA CTD PMID:27939613 NCBI chr 1:214,178,404...214,181,841
Ensembl chr 1:214,178,407...214,181,686
JBrowse link
G M Hras Harvey rat sarcoma virus oncogene decreases expression ISO obeticholic acid results in decreased expression of HRAS mRNA CTD PMID:27939613 NCBI chr 7:141,189,934...141,194,019
Ensembl chr 7:141,189,105...141,194,005
JBrowse link
G H HRAS HRas proto-oncogene, GTPase decreases expression EXP obeticholic acid results in decreased expression of HRAS mRNA CTD PMID:27939613 NCBI chr11:532,242...535,576
Ensembl chr11:532,242...537,287
JBrowse link
G R Hsd17b7 hydroxysteroid (17-beta) dehydrogenase 7 decreases expression ISO obeticholic acid results in decreased expression of HSD17B7 mRNA CTD PMID:27939613 NCBI chr13:88,288,116...88,308,019
Ensembl chr13:88,288,046...88,307,988
JBrowse link
G M Hsd17b7 hydroxysteroid (17-beta) dehydrogenase 7 decreases expression ISO obeticholic acid results in decreased expression of HSD17B7 mRNA CTD PMID:27939613 NCBI chr 1:169,949,535...169,969,242
Ensembl chr 1:169,949,535...169,969,241
JBrowse link
G H HSD17B7 hydroxysteroid 17-beta dehydrogenase 7 decreases expression EXP obeticholic acid results in decreased expression of HSD17B7 mRNA CTD PMID:27939613 NCBI chr 1:162,790,702...162,812,823
Ensembl chr 1:162,790,702...162,812,817
JBrowse link
G R Hsd3b7 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 7 decreases expression ISO obeticholic acid results in decreased expression of HSD3B7 mRNA CTD PMID:27939613 NCBI chr 1:199,248,084...199,251,745
Ensembl chr 1:199,248,470...199,251,740
JBrowse link
G M Hsd3b7 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 7 decreases expression ISO obeticholic acid results in decreased expression of HSD3B7 mRNA CTD PMID:27939613 NCBI chr 7:127,800,609...127,803,802
Ensembl chr 7:127,800,604...127,803,802
JBrowse link
G H HSD3B7 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 7 decreases expression EXP obeticholic acid results in decreased expression of HSD3B7 mRNA CTD PMID:27939613 NCBI chr16:30,985,189...30,989,152
Ensembl chr16:30,985,207...30,989,147
JBrowse link
G R Hspa5 heat shock protein family A (Hsp70) member 5 multiple interactions ISO obeticholic acid inhibits the reaction [Dietary Fats results in increased expression of HSPA5 protein]; obeticholic acid inhibits the reaction [Palmitic Acid results in increased expression of HSPA5 protein] CTD PMID:26655953 NCBI chr 3:13,838,304...13,842,763
Ensembl chr 3:13,838,304...13,842,762
JBrowse link
G M Hspa5 heat shock protein 5 multiple interactions EXP obeticholic acid inhibits the reaction [Dietary Fats results in increased expression of HSPA5 protein]; obeticholic acid inhibits the reaction [Palmitic Acid results in increased expression of HSPA5 protein] CTD PMID:26655953 NCBI chr 2:34,772,090...34,776,529
Ensembl chr 2:34,771,970...34,777,547
JBrowse link
G H HSPA5 heat shock protein family A (Hsp70) member 5 multiple interactions ISO obeticholic acid inhibits the reaction [Dietary Fats results in increased expression of HSPA5 protein]; obeticholic acid inhibits the reaction [Palmitic Acid results in increased expression of HSPA5 protein] CTD PMID:26655953 NCBI chr 9:125,234,853...125,241,343
Ensembl chr 9:125,234,853...125,241,343
Ensembl chr 9:125,234,853...125,241,343
JBrowse link
G R Hspg2 heparan sulfate proteoglycan 2 decreases expression ISO obeticholic acid results in decreased expression of HSPG2 mRNA CTD PMID:27939613 NCBI chr 5:155,812,096...155,913,751 JBrowse link
G M Hspg2 perlecan (heparan sulfate proteoglycan 2) decreases expression ISO obeticholic acid results in decreased expression of HSPG2 mRNA CTD PMID:27939613 NCBI chr 4:137,468,751...137,570,630
Ensembl chr 4:137,468,769...137,570,630
JBrowse link
G H HSPG2 heparan sulfate proteoglycan 2 decreases expression EXP obeticholic acid results in decreased expression of HSPG2 mRNA CTD PMID:27939613 NCBI chr 1:21,822,244...21,937,310
Ensembl chr 1:21,822,244...21,937,310
JBrowse link
G R Id2 inhibitor of DNA binding 2 decreases expression ISO obeticholic acid results in decreased expression of ID2 mRNA CTD PMID:27939613 NCBI chr 6:44,360,077...44,361,908
Ensembl chr 6:44,348,501...44,363,915
JBrowse link
G M Id2 inhibitor of DNA binding 2 decreases expression ISO obeticholic acid results in decreased expression of ID2 mRNA CTD PMID:27939613 NCBI chr12:25,093,799...25,096,092
Ensembl chr12:25,093,799...25,097,140
JBrowse link
G H ID2 inhibitor of DNA binding 2 decreases expression EXP obeticholic acid results in decreased expression of ID2 mRNA CTD PMID:27939613 NCBI chr 2:8,682,056...8,684,461
Ensembl chr 2:8,678,845...8,684,461
JBrowse link
G R Idi1 isopentenyl-diphosphate delta isomerase 1 decreases expression ISO obeticholic acid results in decreased expression of IDI1 mRNA CTD PMID:27939613 NCBI chr17:57,976,266...57,984,036
Ensembl chr17:57,976,268...57,984,036
JBrowse link
G M Idi1 isopentenyl-diphosphate delta isomerase decreases expression ISO obeticholic acid results in decreased expression of IDI1 mRNA CTD PMID:27939613 NCBI chr13:8,885,606...8,892,396
Ensembl chr13:8,885,501...8,892,451
JBrowse link
G H IDI1 isopentenyl-diphosphate delta isomerase 1 decreases expression EXP obeticholic acid results in decreased expression of IDI1 mRNA CTD PMID:27939613 NCBI chr10:1,039,152...1,056,704
Ensembl chr10:1,039,152...1,049,170
Ensembl chr10:1,039,152...1,049,170
JBrowse link
G R Igfals insulin-like growth factor binding protein, acid labile subunit decreases expression ISO obeticholic acid results in decreased expression of IGFALS mRNA CTD PMID:27939613 NCBI chr10:14,240,308...14,243,554
Ensembl chr10:14,240,219...14,243,597
JBrowse link
G M Igfals insulin-like growth factor binding protein, acid labile subunit decreases expression ISO obeticholic acid results in decreased expression of IGFALS mRNA CTD PMID:27939613 NCBI chr17:24,877,844...24,882,011
Ensembl chr17:24,865,997...24,882,010
JBrowse link
G H IGFALS insulin like growth factor binding protein acid labile subunit decreases expression EXP obeticholic acid results in decreased expression of IGFALS mRNA CTD PMID:27939613 NCBI chr16:1,790,413...1,794,908
Ensembl chr16:1,790,413...1,794,971
JBrowse link
G R Il10 interleukin 10 multiple interactions ISO obeticholic acid inhibits the reaction [[Methionine deficiency co-treated with Choline deficiency] results in increased expression of IL10 protein]; obeticholic acid inhibits the reaction [Dietary Fats results in increased expression of IL10 protein] CTD PMID:30745416 NCBI chr13:47,738,933...47,743,392
Ensembl chr13:47,739,526...47,743,392
JBrowse link
G M Il10 interleukin 10 multiple interactions EXP obeticholic acid inhibits the reaction [[Methionine deficiency co-treated with Choline deficiency] results in increased expression of IL10 protein]; obeticholic acid inhibits the reaction [Dietary Fats results in increased expression of IL10 protein] CTD PMID:30745416 NCBI chr 1:131,019,845...131,024,970
Ensembl chr 1:131,019,845...131,024,974
JBrowse link
G H IL10 interleukin 10 multiple interactions ISO obeticholic acid inhibits the reaction [[Methionine deficiency co-treated with Choline deficiency] results in increased expression of IL10 protein]; obeticholic acid inhibits the reaction [Dietary Fats results in increased expression of IL10 protein] CTD PMID:30745416 NCBI chr 1:206,767,602...206,772,494
Ensembl chr 1:206,767,602...206,774,541
JBrowse link
G R Il1b interleukin 1 beta multiple interactions ISO obeticholic acid inhibits the reaction [1-Naphthylisothiocyanate results in increased expression of IL1B mRNA]; obeticholic acid inhibits the reaction [Carbon Tetrachloride results in increased expression of IL1B mRNA] CTD PMID:27865854 PMID:29660435 NCBI chr 3:121,876,256...121,882,637
Ensembl chr 3:121,876,263...121,882,726
JBrowse link
G M Il1b interleukin 1 beta multiple interactions EXP obeticholic acid inhibits the reaction [1-Naphthylisothiocyanate results in increased expression of IL1B mRNA]; obeticholic acid inhibits the reaction [Carbon Tetrachloride results in increased expression of IL1B mRNA] CTD PMID:27865854 PMID:29660435 NCBI chr 2:129,364,569...129,371,164
Ensembl chr 2:129,364,570...129,371,139
JBrowse link
G H IL1B interleukin 1 beta multiple interactions ISO obeticholic acid inhibits the reaction [1-Naphthylisothiocyanate results in increased expression of IL1B mRNA]; obeticholic acid inhibits the reaction [Carbon Tetrachloride results in increased expression of IL1B mRNA] CTD PMID:27865854 PMID:29660435 NCBI chr 2:112,829,751...112,836,843
Ensembl chr 2:112,829,751...112,836,816
JBrowse link
G R Il4 interleukin 4 multiple interactions ISO obeticholic acid promotes the reaction [Carbon Tetrachloride results in increased expression of IL4 mRNA] CTD PMID:27865854 NCBI chr10:38,963,979...38,969,531
Ensembl chr10:38,963,979...38,969,531
JBrowse link
G M Il4 interleukin 4 multiple interactions EXP obeticholic acid promotes the reaction [Carbon Tetrachloride results in increased expression of IL4 mRNA] CTD PMID:27865854 NCBI chr11:53,612,460...53,618,665
Ensembl chr11:53,602,982...53,618,669
JBrowse link
G H IL4 interleukin 4 multiple interactions ISO obeticholic acid promotes the reaction [Carbon Tetrachloride results in increased expression of IL4 mRNA] CTD PMID:27865854 NCBI chr 5:132,673,989...132,682,678
Ensembl chr 5:132,673,986...132,682,678
JBrowse link
G R Il6 interleukin 6 multiple interactions ISO obeticholic acid inhibits the reaction [1-Naphthylisothiocyanate results in increased expression of IL6 mRNA]; obeticholic acid inhibits the reaction [[Methionine deficiency co-treated with Choline deficiency] results in increased expression of IL6 protein]; obeticholic acid inhibits the reaction [Dietary Fats results in increased expression of IL6 protein] CTD PMID:29660435 PMID:30745416 NCBI chr 4:3,043,231...3,047,807
Ensembl chr 4:3,043,231...3,047,807
JBrowse link
G M Il6 interleukin 6 multiple interactions EXP obeticholic acid inhibits the reaction [1-Naphthylisothiocyanate results in increased expression of IL6 mRNA]; obeticholic acid inhibits the reaction [[Methionine deficiency co-treated with Choline deficiency] results in increased expression of IL6 protein]; obeticholic acid inhibits the reaction [Dietary Fats results in increased expression of IL6 protein] CTD PMID:29660435 PMID:30745416 NCBI chr 5:30,013,114...30,019,975
Ensembl chr 5:30,013,114...30,019,981
JBrowse link
G H IL6 interleukin 6 multiple interactions ISO obeticholic acid inhibits the reaction [1-Naphthylisothiocyanate results in increased expression of IL6 mRNA]; obeticholic acid inhibits the reaction [[Methionine deficiency co-treated with Choline deficiency] results in increased expression of IL6 protein]; obeticholic acid inhibits the reaction [Dietary Fats results in increased expression of IL6 protein] CTD PMID:29660435 PMID:30745416 NCBI chr 7:22,725,889...22,732,002
Ensembl chr 7:22,725,884...22,732,002
JBrowse link
G R Il6r interleukin 6 receptor decreases expression ISO obeticholic acid results in decreased expression of IL6R mRNA CTD PMID:27939613 NCBI chr 2:189,196,180...189,255,987
Ensembl chr 2:189,205,701...189,254,628
JBrowse link
G H IL6R interleukin 6 receptor decreases expression EXP obeticholic acid results in decreased expression of IL6R mRNA CTD PMID:27939613 NCBI chr 1:154,405,343...154,469,450
Ensembl chr 1:154,405,193...154,469,450
JBrowse link
G M Il6ra interleukin 6 receptor, alpha decreases expression ISO obeticholic acid results in decreased expression of IL6R mRNA CTD PMID:27939613 NCBI chr 3:89,869,324...89,913,196
Ensembl chr 3:89,864,059...89,913,196
JBrowse link
G R Il6st interleukin 6 cytokine family signal transducer decreases expression ISO obeticholic acid results in decreased expression of IL6ST mRNA CTD PMID:27939613 NCBI chr 2:44,279,199...44,319,427
Ensembl chr 2:44,289,393...44,314,944
JBrowse link
G M Il6st interleukin 6 signal transducer decreases expression ISO obeticholic acid results in decreased expression of IL6ST mRNA CTD PMID:27939613 NCBI chr13:112,464,070...112,506,860
Ensembl chr13:112,464,070...112,510,086
JBrowse link
G H IL6ST interleukin 6 cytokine family signal transducer decreases expression EXP obeticholic acid results in decreased expression of IL6ST mRNA CTD PMID:27939613 NCBI chr 5:55,935,095...55,994,963
Ensembl chr 5:55,935,095...55,995,022
JBrowse link
G R Inhbb inhibin subunit beta B increases expression ISO obeticholic acid results in increased expression of INHBB mRNA CTD PMID:27939613 NCBI chr13:35,436,532...35,442,222
Ensembl chr13:35,436,532...35,442,222
JBrowse link
G M Inhbb inhibin beta-B increases expression ISO obeticholic acid results in increased expression of INHBB mRNA CTD PMID:27939613 NCBI chr 1:119,415,463...119,422,248
Ensembl chr 1:119,415,465...119,422,248
JBrowse link
G H INHBB inhibin subunit beta B increases expression EXP obeticholic acid results in increased expression of INHBB mRNA CTD PMID:27939613 NCBI chr 2:120,346,136...120,351,803
Ensembl chr 2:120,346,136...120,351,803
JBrowse link
G R Irak1 interleukin-1 receptor-associated kinase 1 decreases expression ISO obeticholic acid results in decreased expression of IRAK1 mRNA CTD PMID:27939613 NCBI chr  X:156,716,469...156,726,367
Ensembl chr  X:156,716,604...156,725,977
JBrowse link
G M Irak1 interleukin-1 receptor-associated kinase 1 decreases expression ISO obeticholic acid results in decreased expression of IRAK1 mRNA CTD PMID:27939613 NCBI chr  X:74,013,914...74,023,921
Ensembl chr  X:74,013,914...74,023,918
JBrowse link
G H IRAK1 interleukin 1 receptor associated kinase 1 decreases expression EXP obeticholic acid results in decreased expression of IRAK1 mRNA CTD PMID:27939613 NCBI chr  X:154,010,507...154,019,984
Ensembl chr  X:154,010,506...154,019,902
JBrowse link
G R Irak2 interleukin-1 receptor-associated kinase 2 decreases expression ISO obeticholic acid results in decreased expression of IRAK2 mRNA CTD PMID:27939613 NCBI chr 4:145,594,575...145,651,066
Ensembl chr 4:145,594,575...145,651,053
JBrowse link
G M Irak2 interleukin-1 receptor-associated kinase 2 decreases expression ISO obeticholic acid results in decreased expression of IRAK2 mRNA CTD PMID:27939613 NCBI chr 6:113,638,467...113,695,026
Ensembl chr 6:113,638,467...113,695,026
JBrowse link
G H IRAK2 interleukin 1 receptor associated kinase 2 decreases expression EXP obeticholic acid results in decreased expression of IRAK2 mRNA CTD PMID:27939613 NCBI chr 3:10,164,919...10,243,745
Ensembl chr 3:10,164,919...10,243,745
JBrowse link
G R Jun Jun proto-oncogene, AP-1 transcription factor subunit increases expression ISO obeticholic acid results in increased expression of JUN mRNA CTD PMID:27939613 NCBI chr 5:114,011,184...114,014,277
Ensembl chr 5:114,011,189...114,014,277
JBrowse link
G M Jun jun proto-oncogene increases expression ISO obeticholic acid results in increased expression of JUN mRNA CTD PMID:27939613 NCBI chr 4:95,049,036...95,052,222
Ensembl chr 4:95,049,034...95,052,222
JBrowse link
G H JUN Jun proto-oncogene, AP-1 transcription factor subunit increases expression EXP obeticholic acid results in increased expression of JUN mRNA CTD PMID:27939613 NCBI chr 1:58,780,791...58,784,047
Ensembl chr 1:58,780,791...58,784,047
Ensembl chr 1:58,780,791...58,784,047
JBrowse link
G R Junb JunB proto-oncogene, AP-1 transcription factor subunit decreases expression ISO obeticholic acid results in decreased expression of JUNB mRNA CTD PMID:27939613 NCBI chr19:26,092,972...26,094,756
Ensembl chr19:26,092,974...26,094,756
JBrowse link
G M Junb jun B proto-oncogene decreases expression ISO obeticholic acid results in decreased expression of JUNB mRNA CTD PMID:27939613 NCBI chr 8:84,976,909...84,978,748
Ensembl chr 8:84,974,484...84,978,718
Ensembl chr 8:84,974,484...84,978,718
JBrowse link
G H JUNB JunB proto-oncogene, AP-1 transcription factor subunit decreases expression EXP obeticholic acid results in decreased expression of JUNB mRNA CTD PMID:27939613 NCBI chr19:12,791,486...12,793,315
Ensembl chr19:12,791,486...12,793,315
JBrowse link
G R Jund JunD proto-oncogene, AP-1 transcription factor subunit multiple interactions EXP NR0B2 protein affects the reaction [obeticholic acid inhibits the reaction [JUND protein binds to TIMP1 promoter]] CTD PMID:15860571 NCBI chr16:20,485,028...20,486,707
Ensembl chr16:20,485,029...20,486,707
JBrowse link
G M Jund jun D proto-oncogene multiple interactions ISO NR0B2 protein affects the reaction [obeticholic acid inhibits the reaction [JUND protein binds to TIMP1 promoter]] CTD PMID:15860571 NCBI chr 8:70,697,739...70,700,616
Ensembl chr 8:70,698,949...70,700,616
JBrowse link
G H JUND JunD proto-oncogene, AP-1 transcription factor subunit multiple interactions ISO NR0B2 protein affects the reaction [obeticholic acid inhibits the reaction [JUND protein binds to TIMP1 promoter]] CTD PMID:15860571 NCBI chr19:18,279,694...18,281,622
Ensembl chr19:18,279,694...18,281,622
JBrowse link
G H KRT16P2 keratin 16 pseudogene 2 decreases expression EXP obeticholic acid results in decreased expression of KRT16P2 mRNA CTD PMID:27939613 NCBI chr17:16,830,483...16,832,833
Ensembl chr17:16,829,999...16,832,830
JBrowse link
G H KRT16P3 keratin 16 pseudogene 3 decreases expression EXP obeticholic acid results in decreased expression of KRT16P3 mRNA CTD PMID:27939613 NCBI chr17:20,501,513...20,504,498
Ensembl chr17:20,501,513...20,512,357
JBrowse link
G R Lbr lamin B receptor decreases expression ISO obeticholic acid results in decreased expression of LBR mRNA CTD PMID:27939613 NCBI chr13:100,431,390...100,450,209 JBrowse link
G M Lbr lamin B receptor decreases expression ISO obeticholic acid results in decreased expression of LBR mRNA CTD PMID:27939613 NCBI chr 1:181,815,315...181,842,401
Ensembl chr 1:181,815,335...181,843,046
JBrowse link
G H LBR lamin B receptor decreases expression EXP obeticholic acid results in decreased expression of LBR mRNA CTD PMID:27939613 NCBI chr 1:225,401,502...225,428,821
Ensembl chr 1:225,401,502...225,428,925
JBrowse link
G R Lcat lecithin cholesterol acyltransferase decreases expression ISO obeticholic acid results in decreased expression of LCAT mRNA CTD PMID:27939613 NCBI chr19:37,913,333...37,916,799
Ensembl chr19:37,913,336...37,916,813
JBrowse link
G M Lcat lecithin cholesterol acyltransferase decreases expression ISO obeticholic acid results in decreased expression of LCAT mRNA CTD PMID:27939613 NCBI chr 8:105,939,551...105,943,402
Ensembl chr 8:105,939,551...105,943,382
JBrowse link
G H LCAT lecithin-cholesterol acyltransferase decreases expression EXP obeticholic acid results in decreased expression of LCAT mRNA CTD PMID:27939613 NCBI chr16:67,939,750...67,944,120
Ensembl chr16:67,939,750...67,944,131
JBrowse link
G R Ldlr low density lipoprotein receptor decreases expression ISO obeticholic acid results in decreased expression of LDLR mRNA CTD PMID:27939613 NCBI chr 8:22,750,425...22,773,305
Ensembl chr 8:22,750,336...22,774,903
JBrowse link
G M Ldlr low density lipoprotein receptor decreases expression ISO obeticholic acid results in decreased expression of LDLR mRNA CTD PMID:27939613 NCBI chr 9:21,723,576...21,749,919
Ensembl chr 9:21,723,483...21,749,919
JBrowse link
G H LDLR low density lipoprotein receptor decreases expression EXP obeticholic acid results in decreased expression of LDLR mRNA CTD PMID:27939613 NCBI chr19:11,089,432...11,133,820
Ensembl chr19:11,089,462...11,133,820
Ensembl chr19:11,089,462...11,133,820
JBrowse link
G R Leng8 leukocyte receptor cluster member 8 increases expression ISO obeticholic acid results in increased expression of LENG8 mRNA CTD PMID:27939613 NCBI chr 1:73,722,088...73,734,459
Ensembl chr 1:73,722,088...73,733,788
JBrowse link
G M Leng8 leukocyte receptor cluster (LRC) member 8 increases expression ISO obeticholic acid results in increased expression of LENG8 mRNA CTD PMID:27939613 NCBI chr 7:4,137,013...4,148,177
Ensembl chr 7:4,137,039...4,148,177
JBrowse link
G H LENG8 leukocyte receptor cluster member 8 increases expression EXP obeticholic acid results in increased expression of LENG8 mRNA CTD PMID:27939613 NCBI chr19:54,447,621...54,462,022
Ensembl chr19:54,448,887...54,462,037
Ensembl chr19:54,448,887...54,462,037
JBrowse link
G R Lgi4 leucine-rich repeat LGI family, member 4 increases expression ISO obeticholic acid results in increased expression of LGI4 mRNA CTD PMID:27939613 NCBI chr 1:89,491,588...89,502,939
Ensembl chr 1:89,491,654...89,502,974
JBrowse link
G M Lgi4 leucine-rich repeat LGI family, member 4 increases expression ISO obeticholic acid results in increased expression of LGI4 mRNA CTD PMID:27939613 NCBI chr 7:31,058,909...31,070,935
Ensembl chr 7:31,059,342...31,070,935
JBrowse link
G H LGI4 leucine rich repeat LGI family member 4 increases expression EXP obeticholic acid results in increased expression of LGI4 mRNA CTD PMID:27939613 NCBI chr19:35,124,513...35,135,059
Ensembl chr19:35,124,513...35,142,451
JBrowse link
G R Lime1 Lck interacting transmembrane adaptor 1 decreases expression ISO obeticholic acid results in decreased expression of LIME1 mRNA CTD PMID:27939613 NCBI chr 3:176,881,881...176,888,230
Ensembl chr 3:176,882,027...176,884,350
JBrowse link
G M Lime1 Lck interacting transmembrane adaptor 1 decreases expression ISO obeticholic acid results in decreased expression of LIME1 mRNA CTD PMID:27939613 NCBI chr 2:181,381,235...181,383,628
Ensembl chr 2:181,380,078...181,383,628
JBrowse link
G H LIME1 Lck interacting transmembrane adaptor 1 decreases expression EXP obeticholic acid results in decreased expression of LIME1 mRNA CTD PMID:27939613 NCBI chr20:63,735,701...63,739,103
Ensembl chr20:63,736,283...63,739,103
JBrowse link
G H LINC00870 long intergenic non-protein coding RNA 870 increases expression EXP obeticholic acid results in increased expression of LINC00870 mRNA CTD PMID:27939613 NCBI chr 3:72,151,257...72,174,339
Ensembl chr 3:72,151,236...72,207,776
JBrowse link
G R Lipc lipase C, hepatic type decreases expression ISO obeticholic acid results in decreased expression of LIPC mRNA CTD PMID:27939613 NCBI chr 8:77,272,582...77,398,485
Ensembl chr 8:77,272,570...77,398,248
JBrowse link
G M Lipc lipase, hepatic decreases expression ISO obeticholic acid results in decreased expression of LIPC mRNA CTD PMID:27939613 NCBI chr 9:70,798,128...70,952,221
Ensembl chr 9:70,798,128...70,952,226
JBrowse link
G H LIPC lipase C, hepatic type decreases expression EXP obeticholic acid results in decreased expression of LIPC mRNA CTD PMID:27939613 NCBI chr15:58,410,457...58,569,844
Ensembl chr15:58,410,569...58,569,844
JBrowse link
G H LPA lipoprotein(a) decreases expression EXP obeticholic acid results in decreased expression of LPA mRNA CTD PMID:27939613 NCBI chr 6:160,531,482...160,664,275
Ensembl chr 6:160,531,483...160,664,259
Ensembl chr 6:160,531,483...160,664,259
JBrowse link
G R Lpin1 lipin 1 decreases expression ISO obeticholic acid results in decreased expression of LPIN1 mRNA CTD PMID:27939613 NCBI chr 6:41,796,214...41,905,149
Ensembl chr 6:41,799,749...41,870,046
JBrowse link
G M Lpin1 lipin 1 decreases expression ISO obeticholic acid results in decreased expression of LPIN1 mRNA CTD PMID:27939613 NCBI chr12:16,535,669...16,653,903
Ensembl chr12:16,535,669...16,646,966
JBrowse link
G H LPIN1 lipin 1 decreases expression EXP obeticholic acid results in decreased expression of LPIN1 mRNA CTD PMID:27939613 NCBI chr 2:11,677,544...11,827,409
Ensembl chr 2:11,677,595...11,827,409
JBrowse link
G R Lpin2 lipin 2 decreases expression ISO obeticholic acid results in decreased expression of LPIN2 mRNA CTD PMID:27939613 NCBI chr 9:119,517,101...119,591,533
Ensembl chr 9:119,517,101...119,591,533
JBrowse link
G M Lpin2 lipin 2 decreases expression ISO obeticholic acid results in decreased expression of LPIN2 mRNA CTD PMID:27939613 NCBI chr17:71,183,532...71,249,818
Ensembl chr17:71,182,560...71,249,817
JBrowse link
G H LPIN2 lipin 2 decreases expression EXP obeticholic acid results in decreased expression of LPIN2 mRNA CTD PMID:27939613 NCBI chr18:2,916,994...3,013,201
Ensembl chr18:2,916,994...3,013,315
Ensembl chr18:2,916,994...3,013,315
JBrowse link
G R Lss lanosterol synthase decreases expression ISO obeticholic acid results in decreased expression of LSS mRNA CTD PMID:27939613 NCBI chr20:12,844,522...12,870,474
Ensembl chr20:12,842,884...12,870,497
JBrowse link
G M Lss lanosterol synthase decreases expression ISO obeticholic acid results in decreased expression of LSS mRNA CTD PMID:27939613 NCBI chr10:76,531,565...76,557,139
Ensembl chr10:76,531,588...76,557,138
JBrowse link
G H LSS lanosterol synthase decreases expression EXP obeticholic acid results in decreased expression of LSS mRNA CTD PMID:27939613 NCBI chr21:46,188,446...46,228,774
Ensembl chr21:46,188,141...46,228,824
JBrowse link
G R Maf MAF bZIP transcription factor increases expression ISO obeticholic acid results in increased expression of MAF mRNA CTD PMID:27939613 NCBI chr19:48,179,826...48,200,995
Ensembl chr19:48,194,804...48,196,748
JBrowse link
G M Maf avian musculoaponeurotic fibrosarcoma oncogene homolog increases expression ISO obeticholic acid results in increased expression of MAF mRNA CTD PMID:27939613 NCBI chr 8:115,703,253...115,706,894
Ensembl chr 8:115,682,942...115,707,794
JBrowse link
G H MAF MAF bZIP transcription factor increases expression EXP obeticholic acid results in increased expression of MAF mRNA CTD PMID:27939613 NCBI chr16:79,202,624...79,601,952
Ensembl chr16:79,585,843...79,600,737
JBrowse link
G R Maff MAF bZIP transcription factor F increases expression ISO obeticholic acid results in increased expression of MAFF mRNA CTD PMID:27939613 NCBI chr 7:120,580,743...120,592,095
Ensembl chr 7:120,580,743...120,592,095
JBrowse link
G M Maff v-maf musculoaponeurotic fibrosarcoma oncogene family, protein F (avian) increases expression ISO obeticholic acid results in increased expression of MAFF mRNA CTD PMID:27939613 NCBI chr15:79,346,621...79,359,078
Ensembl chr15:79,346,621...79,359,076
JBrowse link
G H MAFF MAF bZIP transcription factor F increases expression EXP obeticholic acid results in increased expression of MAFF mRNA CTD PMID:27939613 NCBI chr22:38,201,994...38,216,511
Ensembl chr22:38,200,767...38,216,507
JBrowse link
G R Map1lc3b microtubule-associated protein 1 light chain 3 beta multiple interactions ISO obeticholic acid inhibits the reaction [Dietary Fats results in decreased expression of MAP1LC3B protein] CTD PMID:26655953 NCBI chr19:53,635,449...53,643,970
Ensembl chr19:53,629,779...53,646,058
JBrowse link
G M Map1lc3b microtubule-associated protein 1 light chain 3 beta multiple interactions EXP obeticholic acid inhibits the reaction [Dietary Fats results in decreased expression of MAP1LC3B protein] CTD PMID:26655953 NCBI chr 8:121,590,438...121,598,760
Ensembl chr 8:121,590,361...121,598,760
JBrowse link
G H MAP1LC3B microtubule associated protein 1 light chain 3 beta multiple interactions ISO obeticholic acid inhibits the reaction [Dietary Fats results in decreased expression of MAP1LC3B protein] CTD PMID:26655953 NCBI chr16:87,392,336...87,404,774
Ensembl chr16:87,383,953...87,404,779
JBrowse link
G R Map2k3 mitogen activated protein kinase kinase 3 decreases expression ISO obeticholic acid results in decreased expression of MAP2K3 mRNA CTD PMID:27939613 NCBI chr10:45,089,455...45,110,802
Ensembl chr10:47,182,433...47,203,753
Ensembl chr10:47,182,433...47,203,753
JBrowse link
G M Map2k3 mitogen-activated protein kinase kinase 3 decreases expression ISO obeticholic acid results in decreased expression of MAP2K3 mRNA CTD PMID:27939613 NCBI chr11:60,932,054...60,952,811
Ensembl chr11:60,932,033...60,952,811
JBrowse link
G H MAP2K3 mitogen-activated protein kinase kinase 3 decreases expression EXP obeticholic acid results in decreased expression of MAP2K3 mRNA CTD PMID:27939613 NCBI chr17:21,284,679...21,315,240
Ensembl chr17:21,284,672...21,315,232
JBrowse link
G R Map2k6 mitogen-activated protein kinase kinase 6 decreases expression ISO obeticholic acid results in decreased expression of MAP2K6 mRNA CTD PMID:27939613 NCBI chr10:98,707,160...98,823,054
Ensembl chr10:98,706,960...98,823,287
JBrowse link
G M Map2k6 mitogen-activated protein kinase kinase 6 decreases expression ISO obeticholic acid results in decreased expression of MAP2K6 mRNA CTD PMID:27939613 NCBI chr11:110,399,102...110,525,522
Ensembl chr11:110,399,122...110,525,522
JBrowse link
G H MAP2K6 mitogen-activated protein kinase kinase 6 decreases expression EXP obeticholic acid results in decreased expression of MAP2K6 mRNA CTD PMID:27939613 NCBI chr17:69,414,697...69,553,865
Ensembl chr17:69,414,697...69,553,865
JBrowse link
G R Map2k7 mitogen activated protein kinase kinase 7 decreases expression ISO obeticholic acid results in decreased expression of MAP2K7 mRNA CTD PMID:27939613 NCBI chr12:2,546,278...2,555,310
Ensembl chr12:2,548,218...2,555,164
JBrowse link
G M Map2k7 mitogen-activated protein kinase kinase 7 decreases expression ISO obeticholic acid results in decreased expression of MAP2K7 mRNA CTD PMID:27939613 NCBI chr 8:4,238,740...4,247,897
Ensembl chr 8:4,238,740...4,247,897
Ensembl chr 8:4,238,740...4,247,897
JBrowse link
G H MAP2K7 mitogen-activated protein kinase kinase 7 decreases expression EXP obeticholic acid results in decreased expression of MAP2K7 mRNA CTD PMID:27939613 NCBI chr19:7,903,785...7,914,478
Ensembl chr19:7,903,843...7,914,478
JBrowse link
G R Map3k14 mitogen-activated protein kinase kinase kinase 14 decreases expression ISO obeticholic acid results in decreased expression of MAP3K14 mRNA CTD PMID:27939613 NCBI chr10:91,303,428...91,353,601
Ensembl chr10:91,303,428...91,353,601
JBrowse link
G M Map3k14 mitogen-activated protein kinase kinase kinase 14 decreases expression ISO obeticholic acid results in decreased expression of MAP3K14 mRNA CTD PMID:27939613 NCBI chr11:103,219,764...103,267,401
Ensembl chr11:103,219,762...103,267,472
JBrowse link
G H MAP3K14 mitogen-activated protein kinase kinase kinase 14 decreases expression EXP obeticholic acid results in decreased expression of MAP3K14 mRNA CTD PMID:27939613 NCBI chr17:45,263,119...45,317,048
Ensembl chr17:45,263,119...45,317,029
JBrowse link
G R Map3k5 mitogen-activated protein kinase kinase kinase 5 decreases expression ISO obeticholic acid results in decreased expression of MAP3K5 mRNA CTD PMID:27939613 NCBI chr 1:15,412,603...15,613,752
Ensembl chr 1:15,412,603...15,613,746
JBrowse link
G M Map3k5 mitogen-activated protein kinase kinase kinase 5 decreases expression ISO obeticholic acid results in decreased expression of MAP3K5 mRNA CTD PMID:27939613 NCBI chr10:19,934,101...20,142,750
Ensembl chr10:19,934,472...20,142,753
JBrowse link
G H MAP3K5 mitogen-activated protein kinase kinase kinase 5 decreases expression EXP obeticholic acid results in decreased expression of MAP3K5 mRNA CTD PMID:27939613 NCBI chr 6:136,557,046...136,793,098
Ensembl chr 6:136,557,046...136,792,477
JBrowse link
G R Map3k8 mitogen-activated protein kinase kinase kinase 8 increases expression ISO obeticholic acid results in increased expression of MAP3K8 mRNA CTD PMID:27939613 NCBI chr17:56,109,403...56,129,925
Ensembl chr17:56,109,549...56,129,919
JBrowse link
G M Map3k8 mitogen-activated protein kinase kinase kinase 8 increases expression ISO obeticholic acid results in increased expression of MAP3K8 mRNA CTD PMID:27939613 NCBI chr18:4,331,325...4,352,953
Ensembl chr18:4,331,327...4,353,015
JBrowse link
G H MAP3K8 mitogen-activated protein kinase kinase kinase 8 increases expression EXP obeticholic acid results in increased expression of MAP3K8 mRNA CTD PMID:27939613 NCBI chr10:30,434,021...30,461,833
Ensembl chr10:30,434,021...30,461,833
JBrowse link
G R Mapk1 mitogen activated protein kinase 1 multiple interactions ISO obeticholic acid inhibits the reaction [Carbon Tetrachloride results in increased phosphorylation of MAPK1 protein] CTD PMID:27865854 NCBI chr11:88,203,863...88,273,301
Ensembl chr11:88,211,599...88,273,254
JBrowse link
G M Mapk1 mitogen-activated protein kinase 1 multiple interactions EXP obeticholic acid inhibits the reaction [Carbon Tetrachloride results in increased phosphorylation of MAPK1 protein] CTD PMID:27865854 NCBI chr16:16,983,382...17,047,453
Ensembl chr16:16,983,382...17,047,453
JBrowse link
G H MAPK1 mitogen-activated protein kinase 1 multiple interactions ISO obeticholic acid inhibits the reaction [Carbon Tetrachloride results in increased phosphorylation of MAPK1 protein] CTD PMID:27865854 NCBI chr22:21,759,657...21,867,680
Ensembl chr22:21,754,500...21,867,680
Ensembl chr22:21,754,500...21,867,680
JBrowse link
G R Mapk11 mitogen-activated protein kinase 11 decreases expression ISO obeticholic acid results in decreased expression of MAPK11 mRNA CTD PMID:27939613 NCBI chr 7:130,121,678...130,129,199
Ensembl chr 7:130,121,687...130,128,604
JBrowse link
G M Mapk11 mitogen-activated protein kinase 11 decreases expression ISO obeticholic acid results in decreased expression of MAPK11 mRNA CTD PMID:27939613 NCBI chr15:89,142,482...89,149,606
Ensembl chr15:89,142,486...89,149,628
JBrowse link
G H MAPK11 mitogen-activated protein kinase 11 decreases expression EXP obeticholic acid results in decreased expression of MAPK11 mRNA CTD PMID:27939613 NCBI chr22:50,263,713...50,270,380
Ensembl chr22:50,263,713...50,270,767
JBrowse link
G R Mapk12 mitogen-activated protein kinase 12 decreases expression ISO obeticholic acid results in decreased expression of MAPK12 mRNA CTD PMID:27939613 NCBI chr 7:130,109,214...130,120,918
Ensembl chr 7:130,109,663...130,120,579
JBrowse link
G M Mapk12 mitogen-activated protein kinase 12 decreases expression ISO obeticholic acid results in decreased expression of MAPK12 mRNA CTD PMID:27939613 NCBI chr15:89,130,584...89,141,577
Ensembl chr15:89,130,584...89,140,703
JBrowse link
G H MAPK12 mitogen-activated protein kinase 12 decreases expression EXP obeticholic acid results in decreased expression of MAPK12 mRNA CTD PMID:27939613 NCBI chr22:50,252,901...50,261,683
Ensembl chr22:50,245,450...50,261,716
JBrowse link
G R Mapk3 mitogen activated protein kinase 3 multiple interactions ISO obeticholic acid inhibits the reaction [Carbon Tetrachloride results in increased phosphorylation of MAPK3 protein] CTD PMID:27865854 NCBI chr 1:198,192,773...198,198,975
Ensembl chr 1:198,192,773...198,198,975
JBrowse link
G M Mapk3 mitogen-activated protein kinase 3 multiple interactions EXP obeticholic acid inhibits the reaction [Carbon Tetrachloride results in increased phosphorylation of MAPK3 protein] CTD PMID:27865854 NCBI chr 7:126,759,626...126,765,816
Ensembl chr 7:126,759,601...126,765,819
JBrowse link
G H MAPK3 mitogen-activated protein kinase 3 multiple interactions ISO obeticholic acid inhibits the reaction [Carbon Tetrachloride results in increased phosphorylation of MAPK3 protein] CTD PMID:27865854 NCBI chr16:30,114,105...30,123,309
Ensembl chr16:30,114,105...30,123,506
JBrowse link
G R Mdh1 malate dehydrogenase 1 increases expression ISO obeticholic acid results in increased expression of MDH1 mRNA CTD PMID:27939613 NCBI chr14:106,378,349...106,393,642
Ensembl chr14:106,378,942...106,393,670
JBrowse link
G M Mdh1 malate dehydrogenase 1, NAD (soluble) increases expression ISO obeticholic acid results in increased expression of MDH1 mRNA CTD PMID:27939613 NCBI chr11:21,556,692...21,571,934
Ensembl chr11:21,556,692...21,572,367
JBrowse link
G H MDH1 malate dehydrogenase 1 increases expression EXP obeticholic acid results in increased expression of MDH1 mRNA CTD PMID:27939613 NCBI chr 2:63,588,963...63,607,197
Ensembl chr 2:63,588,609...63,607,197
JBrowse link
G R Metrnl meteorin-like, glial cell differentiation regulator decreases expression ISO obeticholic acid results in decreased expression of METRNL mRNA CTD PMID:27939613 NCBI chr10:110,893,261...110,907,256
Ensembl chr10:110,893,232...110,907,243
JBrowse link
G M Metrnl meteorin, glial cell differentiation regulator-like decreases expression ISO obeticholic acid results in decreased expression of METRNL mRNA CTD PMID:27939613 NCBI chr11:121,702,427...121,717,389
Ensembl chr11:121,701,544...121,716,306
JBrowse link
G H METRNL meteorin like, glial cell differentiation regulator decreases expression EXP obeticholic acid results in decreased expression of METRNL mRNA CTD PMID:27939613 NCBI chr17:83,079,609...83,095,122
Ensembl chr17:83,079,609...83,095,122
JBrowse link
G R Mfsd2a major facilitator superfamily domain containing 2A increases expression ISO obeticholic acid results in increased expression of MFSD2A mRNA CTD PMID:27939613 NCBI chr 5:140,642,865...140,657,759
Ensembl chr 5:140,642,885...140,657,745
JBrowse link
G M Mfsd2a major facilitator superfamily domain containing 2A increases expression ISO obeticholic acid results in increased expression of MFSD2A mRNA CTD PMID:27939613 NCBI chr 4:122,946,850...122,961,194
Ensembl chr 4:122,946,850...122,961,188
JBrowse link
G H MFSD2A major facilitator superfamily domain containing 2A increases expression EXP obeticholic acid results in increased expression of MFSD2A mRNA CTD PMID:27939613 NCBI chr 1:39,955,145...39,969,956
Ensembl chr 1:39,955,112...39,969,968
JBrowse link
G R Mlkl mixed lineage kinase domain like pseudokinase decreases expression ISO obeticholic acid results in decreased expression of MLKL mRNA CTD PMID:27939613 NCBI chr19:43,508,416...43,535,050
Ensembl chr19:43,506,976...43,528,851
JBrowse link
G M Mlkl mixed lineage kinase domain-like decreases expression ISO obeticholic acid results in decreased expression of MLKL mRNA CTD PMID:27939613 NCBI chr 8:111,311,255...111,338,479
Ensembl chr 8:111,311,797...111,338,177
JBrowse link
G H MLKL mixed lineage kinase domain like pseudokinase decreases expression EXP obeticholic acid results in decreased expression of MLKL mRNA CTD PMID:27939613 NCBI chr16:74,671,855...74,700,889
Ensembl chr16:74,671,855...74,700,960
JBrowse link
G R Mllt11 MLLT11, transcription factor 7 cofactor increases expression ISO obeticholic acid results in increased expression of MLLT11 mRNA CTD PMID:27939613 NCBI chr 2:196,392,936...196,402,106
Ensembl chr 2:196,392,938...196,402,106
JBrowse link
G M Mllt11 myeloid/lymphoid or mixed-lineage leukemia; translocated to, 11 increases expression ISO obeticholic acid results in increased expression of MLLT11 mRNA CTD PMID:27939613 NCBI chr 3:95,218,544...95,229,632
Ensembl chr 3:95,219,135...95,232,171
JBrowse link
G H MLLT11 MLLT11 transcription factor 7 cofactor increases expression EXP obeticholic acid results in increased expression of MLLT11 mRNA CTD PMID:27939613 NCBI chr 1:151,060,397...151,069,544
Ensembl chr 1:151,060,397...151,069,544
Ensembl chr 1:151,060,397...151,069,544
JBrowse link
G R Mmp2 matrix metallopeptidase 2 increases activity EXP obeticholic acid results in increased activity of MMP2 protein CTD PMID:15860571 NCBI chr19:15,542,771...15,570,589
Ensembl chr19:15,542,765...15,570,611
JBrowse link
G M Mmp2 matrix metallopeptidase 2 increases activity ISO obeticholic acid results in increased activity of MMP2 protein CTD PMID:15860571 NCBI chr 8:92,827,290...92,853,421
Ensembl chr 8:92,827,291...92,853,420
JBrowse link
G H MMP2 matrix metallopeptidase 2 increases activity ISO obeticholic acid results in increased activity of MMP2 protein CTD PMID:15860571 NCBI chr16:55,478,830...55,506,691
Ensembl chr16:55,389,700...55,506,691
JBrowse link
G R Mrtfb myocardin related transcription factor B decreases expression ISO obeticholic acid results in decreased expression of MRTFB mRNA CTD PMID:27939613 NCBI chr10:1,151,163...1,273,269 JBrowse link
G M Mrtfb myocardin related transcription factor B decreases expression ISO obeticholic acid results in decreased expression of MRTFB mRNA CTD PMID:27939613 NCBI chr16:13,256,056...13,417,529
Ensembl chr16:13,256,481...13,417,529
JBrowse link
G H MRTFB myocardin related transcription factor B decreases expression EXP obeticholic acid results in decreased expression of MRTFB mRNA CTD PMID:27939613 NCBI chr16:14,071,062...14,266,779
Ensembl chr16:14,071,321...14,266,773
Ensembl chr16:14,071,321...14,266,773
JBrowse link
G R Msmo1 methylsterol monooxygenase 1 decreases expression ISO obeticholic acid results in decreased expression of MSMO1 mRNA CTD PMID:27939613 NCBI chr16:26,859,441...26,875,880
Ensembl chr16:26,859,397...26,875,973
JBrowse link
G M Msmo1 methylsterol monoxygenase 1 decreases expression ISO obeticholic acid results in decreased expression of MSMO1 mRNA CTD PMID:27939613 NCBI chr 8:64,718,123...64,733,578
Ensembl chr 8:64,718,139...64,733,792
JBrowse link
G H MSMO1 methylsterol monooxygenase 1 decreases expression EXP obeticholic acid results in decreased expression of MSMO1 mRNA CTD PMID:27939613 NCBI chr 4:165,327,669...165,343,164
Ensembl chr 4:165,327,667...165,343,164
JBrowse link
G H MT1H metallothionein 1H decreases expression EXP obeticholic acid results in decreased expression of MT1H mRNA CTD PMID:27939613 NCBI chr16:56,669,814...56,671,129
Ensembl chr16:56,669,814...56,671,129
JBrowse link
G R Mvd mevalonate diphosphate decarboxylase decreases expression ISO obeticholic acid results in decreased expression of MVD mRNA CTD PMID:27939613 NCBI chr19:55,258,910...55,268,933
Ensembl chr19:55,258,905...55,268,951
JBrowse link
G M Mvd mevalonate (diphospho) decarboxylase decreases expression ISO obeticholic acid results in decreased expression of MVD mRNA CTD PMID:27939613 NCBI chr 8:122,433,596...122,443,422
Ensembl chr 8:122,433,601...122,443,422
JBrowse link
G H MVD mevalonate diphosphate decarboxylase decreases expression EXP obeticholic acid results in decreased expression of MVD mRNA CTD PMID:27939613 NCBI chr16:88,651,935...88,663,153
Ensembl chr16:88,651,935...88,663,161
JBrowse link
G R Mvk mevalonate kinase decreases expression ISO obeticholic acid results in decreased expression of MVK mRNA CTD PMID:27939613 NCBI chr12:47,904,266...47,920,457
Ensembl chr12:47,904,719...47,919,400
JBrowse link
G M Mvk mevalonate kinase decreases expression ISO obeticholic acid results in decreased expression of MVK mRNA CTD PMID:27939613 NCBI chr 5:114,444,264...114,460,591
Ensembl chr 5:114,444,269...114,460,591
JBrowse link
G H MVK mevalonate kinase decreases expression EXP obeticholic acid results in decreased expression of MVK mRNA CTD PMID:27939613 NCBI chr12:109,573,461...109,598,125
Ensembl chr12:109,573,255...109,598,125
JBrowse link
G R Myc MYC proto-oncogene, bHLH transcription factor decreases expression ISO obeticholic acid results in decreased expression of MYC mRNA CTD PMID:27939613 NCBI chr 7:102,586,313...102,591,240
Ensembl chr 7:102,586,313...102,591,240
JBrowse link
G M Myc myelocytomatosis oncogene decreases expression ISO obeticholic acid results in decreased expression of MYC mRNA CTD PMID:27939613 NCBI chr15:61,985,341...61,990,361
Ensembl chr15:61,985,391...61,990,374
JBrowse link
G H MYC MYC proto-oncogene, bHLH transcription factor decreases expression EXP obeticholic acid results in decreased expression of MYC mRNA CTD PMID:27939613 NCBI chr 8:127,735,434...127,742,951
Ensembl chr 8:127,735,434...127,742,951
JBrowse link
G R Nfe2l2 nuclear factor, erythroid 2-like 2 increases expression ISO obeticholic acid results in increased expression of NFE2L2 mRNA CTD PMID:27939613 NCBI chr 3:62,497,568...62,525,146
Ensembl chr 3:62,497,571...62,524,996
JBrowse link
G M Nfe2l2 nuclear factor, erythroid derived 2, like 2 increases expression ISO obeticholic acid results in increased expression of NFE2L2 mRNA CTD PMID:27939613 NCBI chr 2:75,675,513...75,704,663
Ensembl chr 2:75,675,513...75,704,641
JBrowse link
G H NFE2L2 nuclear factor, erythroid 2 like 2 increases expression EXP obeticholic acid results in increased expression of NFE2L2 mRNA CTD PMID:27939613 NCBI chr 2:177,230,303...177,265,131
Ensembl chr 2:177,227,595...177,392,697
JBrowse link
G R Nfkb1 nuclear factor kappa B subunit 1 increases expression
multiple interactions
ISO
EXP
obeticholic acid results in increased expression of NFKB1 mRNA
Obeticholic acid inhibits the reaction [ethanol increases expression of NF-kB protein in liver]
CTD PMID:27939613, PMID:27939985 RGD:15036816 NCBI chr 2:240,773,520...240,890,053
Ensembl chr 2:240,773,456...240,866,689
JBrowse link
G M Nfkb1 nuclear factor of kappa light polypeptide gene enhancer in B cells 1, p105 increases expression
multiple interactions
ISO obeticholic acid results in increased expression of NFKB1 mRNA
Obeticholic acid inhibits the reaction [ethanol increases expression of NF-kB protein in liver]
CTD PMID:27939613, PMID:27939985 RGD:15036816 NCBI chr 3:135,584,655...135,691,969
Ensembl chr 3:135,584,655...135,691,547
JBrowse link
G H NFKB1 nuclear factor kappa B subunit 1 increases expression
multiple interactions
EXP
ISO
obeticholic acid results in increased expression of NFKB1 mRNA
Obeticholic acid inhibits the reaction [ethanol increases expression of NF-kB protein in liver]
CTD PMID:27939613, PMID:27939985 RGD:15036816 NCBI chr 4:102,501,266...102,617,302
Ensembl chr 4:102,501,331...102,617,302
JBrowse link
G R Nfkb2 nuclear factor kappa B subunit 2 decreases expression ISO obeticholic acid results in decreased expression of NFKB2 mRNA CTD PMID:27939613 NCBI chr 1:266,050,634...266,059,277
Ensembl chr 1:266,053,002...266,059,256
JBrowse link
G M Nfkb2 nuclear factor of kappa light polypeptide gene enhancer in B cells 2, p49/p100 decreases expression ISO obeticholic acid results in decreased expression of NFKB2 mRNA CTD PMID:27939613 NCBI chr19:46,300,994...46,312,400
Ensembl chr19:46,304,320...46,312,385
JBrowse link
G H NFKB2 nuclear factor kappa B subunit 2 decreases expression EXP obeticholic acid results in decreased expression of NFKB2 mRNA CTD PMID:27939613 NCBI chr10:102,394,110...102,402,529
Ensembl chr10:102,394,110...102,402,524
JBrowse link
G R Nfkbia NFKB inhibitor alpha multiple interactions EXP Obeticholic acid inhibits the reaction [ethanol decreases expression of Nfkbia protein in liver] RGD PMID:27939985 RGD:15036816 NCBI chr 6:76,267,227...76,270,457
Ensembl chr 6:76,267,228...76,270,457
JBrowse link
G M Nfkbia nuclear factor of kappa light polypeptide gene enhancer in B cells inhibitor, alpha multiple interactions ISO Obeticholic acid inhibits the reaction [ethanol decreases expression of Nfkbia protein in liver] RGD PMID:27939985 RGD:15036816 NCBI chr12:55,489,409...55,492,647
Ensembl chr12:55,489,410...55,492,647
JBrowse link
G H NFKBIA NFKB inhibitor alpha multiple interactions ISO Obeticholic acid inhibits the reaction [ethanol decreases expression of Nfkbia protein in liver] RGD PMID:27939985 RGD:15036816 NCBI chr14:35,401,513...35,404,749
Ensembl chr14:35,401,511...35,404,749
Ensembl chr14:35,401,511...35,404,749
JBrowse link
G R Nlrp3 NLR family, pyrin domain containing 3 multiple interactions EXP Obeticholic acid inhibits the reaction [ethanol increases expression of Nrlp3 protein in liver] RGD PMID:27939985 RGD:15036816 NCBI chr10:45,884,324...45,918,290
Ensembl chr10:45,893,018...45,918,254
JBrowse link
G M Nlrp3 NLR family, pyrin domain containing 3 multiple interactions ISO Obeticholic acid inhibits the reaction [ethanol increases expression of Nrlp3 protein in liver] RGD PMID:27939985 RGD:15036816 NCBI chr11:59,541,569...59,566,955
Ensembl chr11:59,541,568...59,566,956
JBrowse link
G H NLRP3 NLR family pyrin domain containing 3 multiple interactions ISO Obeticholic acid inhibits the reaction [ethanol increases expression of Nrlp3 protein in liver] RGD PMID:27939985 RGD:15036816 NCBI chr 1:247,416,163...247,448,823
Ensembl chr 1:247,416,156...247,449,108
JBrowse link
G R Npw neuropeptide W decreases expression ISO obeticholic acid results in decreased expression of NPW mRNA CTD PMID:27939613 NCBI chr10:14,021,187...14,022,452
Ensembl chr10:14,021,187...14,022,452
JBrowse link
G M Npw neuropeptide W decreases expression ISO obeticholic acid results in decreased expression of NPW mRNA CTD PMID:27939613 NCBI chr17:24,657,329...24,658,552
Ensembl chr17:24,657,330...24,658,457
JBrowse link
G H NPW neuropeptide W decreases expression EXP obeticholic acid results in decreased expression of NPW mRNA CTD PMID:27939613 NCBI chr16:2,019,785...2,020,755
Ensembl chr16:2,009,926...2,020,755
JBrowse link
G R Nr0b2 nuclear receptor subfamily 0, group B, member 2 multiple interactions
increases expression
ISO
EXP
obeticholic acid promotes the reaction [PRMT2 protein binds to NR0B2 promoter]
Obeticholic acid inhibits the reaction [ethanol decreases expression of Nr0b2 protein in liver and intestine]
NR0B2 protein affects the reaction [obeticholic acid inhibits the reaction [JUND protein binds to TIMP1 promoter]]; NR0B2 protein affects the reaction [obeticholic acid results in decreased expression of and results in decreased secretion of TIMP1 protein]; obeticholic acid inhibits the reaction [Isoniazid results in decreased expression of NR0B2 mRNA]; obeticholic acid inhibits the reaction [Pyrazinamide results in decreased expression of NR0B2 mRNA]
obeticholic acid results in increased expression of NR0B2 mRNA; obeticholic acid results in increased expression of NR0B2 protein
CTD PMID:15644430 PMID:15860571 PMID:15911693 PMID:15980055 PMID:26655953 PMID:27255380 PMID:27939613 PMID:32673658, PMID:27939985 RGD:15036816 NCBI chr 5:151,776,004...151,779,319
Ensembl chr 5:151,776,004...151,779,319
JBrowse link
G M Nr0b2 nuclear receptor subfamily 0, group B, member 2 multiple interactions
increases expression
ISO
EXP
obeticholic acid promotes the reaction [PRMT2 protein binds to NR0B2 promoter]
Obeticholic acid inhibits the reaction [ethanol decreases expression of Nr0b2 protein in liver and intestine]
NR0B2 protein affects the reaction [obeticholic acid inhibits the reaction [JUND protein binds to TIMP1 promoter]]; NR0B2 protein affects the reaction [obeticholic acid results in decreased expression of and results in decreased secretion of TIMP1 protein]; obeticholic acid inhibits the reaction [Isoniazid results in decreased expression of NR0B2 mRNA]; obeticholic acid inhibits the reaction [Pyrazinamide results in decreased expression of NR0B2 mRNA]
obeticholic acid results in increased expression of NR0B2 mRNA; obeticholic acid results in increased expression of NR0B2 protein
CTD PMID:15644430 PMID:15860571 PMID:15911693 PMID:15980055 PMID:26655953 PMID:27255380 PMID:27939613 PMID:32673658, PMID:27939985 RGD:15036816 NCBI chr 4:133,553,376...133,556,686
Ensembl chr 4:133,553,376...133,556,536
JBrowse link
G H NR0B2 nuclear receptor subfamily 0 group B member 2 multiple interactions
increases expression
EXP
ISO
obeticholic acid promotes the reaction [PRMT2 protein binds to NR0B2 promoter]
Obeticholic acid inhibits the reaction [ethanol decreases expression of Nr0b2 protein in liver and intestine]
NR0B2 protein affects the reaction [obeticholic acid inhibits the reaction [JUND protein binds to TIMP1 promoter]]; NR0B2 protein affects the reaction [obeticholic acid results in decreased expression of and results in decreased secretion of TIMP1 protein]; obeticholic acid inhibits the reaction [Isoniazid results in decreased expression of NR0B2 mRNA]; obeticholic acid inhibits the reaction [Pyrazinamide results in decreased expression of NR0B2 mRNA]
obeticholic acid results in increased expression of NR0B2 mRNA; obeticholic acid results in increased expression of NR0B2 protein
CTD PMID:15644430 PMID:15860571 PMID:15911693 PMID:15980055 PMID:26655953 PMID:27255380 PMID:27939613 PMID:32673658, PMID:27939985 RGD:15036816 NCBI chr 1:26,911,489...26,914,110
Ensembl chr 1:26,911,489...26,913,975
JBrowse link
G R Nr1h4 nuclear receptor subfamily 1, group H, member 4 increases activity
multiple interactions
increases expression
increases response to substance
ISO
EXP
obeticholic acid results in increased activity of NR1H4 protein
Obeticholic acid inhibits the reaction [ethanol decreases expression of Nr1h4 mRNA and protein in liver and liver cell nuclei and intestine]
obeticholic acid increases expression of Nr1H4 mRNA in rat hepatic stellate cells; obeticholic acid increases expression of Nr1h4 mRNA in bile duct ligation and porcine serum induced models of cirrhosis in rat
obeticholic acid results in increased expression of NR1H4 protein
obeticholic acid results in increased expression of NR1H4 mRNA
obeticholic acid binds to and results in increased activity of NR1H4 protein; obeticholic acid inhibits the reaction [Isoniazid results in decreased expression of NR1H4 mRNA]; obeticholic acid inhibits the reaction [Pyrazinamide results in decreased expression of NR1H4 mRNA]
NR1H4 protein results in increased susceptibility to obeticholic acid
NR1H4 affects the reaction [obeticholic acid results in increased expression of FOXM1 mRNA]; NR1H4 gene mutant form inhibits the reaction [obeticholic acid inhibits the reaction [TNF results in increased expression of SELP mRNA]]; NR1H4 gene mutant form inhibits the reaction [obeticholic acid results in increased expression of FABP6 mRNA]; NR1H4 gene mutant form inhibits the reaction [obeticholic acid results in increased expression of FGF15 mRNA]; NR1H4 promotes the reaction [obeticholic acid promotes the reaction [1-Naphthylisothiocyanate results in increased expression of ABCC2 mRNA]]; obeticholic acid binds to and results in increased activity of NR1H4 protein; obeticholic acid inhibits the reaction [1-Naphthylisothiocyanate results in decreased expression of NR1H4 mRNA]
obeticholic acid binds to and results in increased activity of NR1H4 protein; obeticholic acid promotes the reaction [NR1H4 protein binds to PRMT1 protein]
CTD PMID:15860571 PMID:15911693 PMID:15980055 PMID:17567710 PMID:21242261 PMID:22135065 PMID:22918042 PMID:27255380 PMID:27865854 PMID:27871908 PMID:28887089 PMID:29660435 PMID:32673658, PMID:27939985, PMID:15980055 RGD:15036816, RGD:1625201 NCBI chr 7:30,003,429...30,162,095
Ensembl chr 7:30,003,429...30,162,056
JBrowse link
G M Nr1h4 nuclear receptor subfamily 1, group H, member 4 increases activity
multiple interactions
increases expression
increases response to substance
ISO
EXP
obeticholic acid results in increased activity of NR1H4 protein
Obeticholic acid inhibits the reaction [ethanol decreases expression of Nr1h4 mRNA and protein in liver and liver cell nuclei and intestine]
obeticholic acid increases expression of Nr1H4 mRNA in rat hepatic stellate cells; obeticholic acid increases expression of Nr1h4 mRNA in bile duct ligation and porcine serum induced models of cirrhosis in rat
obeticholic acid results in increased expression of NR1H4 protein
obeticholic acid results in increased expression of NR1H4 mRNA
obeticholic acid binds to and results in increased activity of NR1H4 protein; obeticholic acid inhibits the reaction [Isoniazid results in decreased expression of NR1H4 mRNA]; obeticholic acid inhibits the reaction [Pyrazinamide results in decreased expression of NR1H4 mRNA]
NR1H4 protein results in increased susceptibility to obeticholic acid
NR1H4 affects the reaction [obeticholic acid results in increased expression of FOXM1 mRNA]; NR1H4 gene mutant form inhibits the reaction [obeticholic acid inhibits the reaction [TNF results in increased expression of SELP mRNA]]; NR1H4 gene mutant form inhibits the reaction [obeticholic acid results in increased expression of FABP6 mRNA]; NR1H4 gene mutant form inhibits the reaction [obeticholic acid results in increased expression of FGF15 mRNA]; NR1H4 promotes the reaction [obeticholic acid promotes the reaction [1-Naphthylisothiocyanate results in increased expression of ABCC2 mRNA]]; obeticholic acid binds to and results in increased activity of NR1H4 protein; obeticholic acid inhibits the reaction [1-Naphthylisothiocyanate results in decreased expression of NR1H4 mRNA]
obeticholic acid binds to and results in increased activity of NR1H4 protein; obeticholic acid promotes the reaction [NR1H4 protein binds to PRMT1 protein]
CTD PMID:15860571 PMID:15911693 PMID:15980055 PMID:17567710 PMID:21242261 PMID:22135065 PMID:22918042 PMID:27255380 PMID:27865854 PMID:27871908 PMID:28887089 PMID:29660435 PMID:32673658, PMID:27939985, PMID:15980055 RGD:15036816, RGD:1625201 NCBI chr10:89,454,234...89,533,645
Ensembl chr10:89,454,234...89,533,585
JBrowse link
G H NR1H4 nuclear receptor subfamily 1 group H member 4 increases activity
multiple interactions
increases expression
increases response to substance
EXP
ISO
obeticholic acid results in increased activity of NR1H4 protein
Obeticholic acid inhibits the reaction [ethanol decreases expression of Nr1h4 mRNA and protein in liver and liver cell nuclei and intestine]
obeticholic acid increases expression of Nr1H4 mRNA in rat hepatic stellate cells; obeticholic acid increases expression of Nr1h4 mRNA in bile duct ligation and porcine serum induced models of cirrhosis in rat
obeticholic acid results in increased expression of NR1H4 protein
obeticholic acid results in increased expression of NR1H4 mRNA
obeticholic acid binds to and results in increased activity of NR1H4 protein; obeticholic acid inhibits the reaction [Isoniazid results in decreased expression of NR1H4 mRNA]; obeticholic acid inhibits the reaction [Pyrazinamide results in decreased expression of NR1H4 mRNA]
NR1H4 protein results in increased susceptibility to obeticholic acid
NR1H4 affects the reaction [obeticholic acid results in increased expression of FOXM1 mRNA]; NR1H4 gene mutant form inhibits the reaction [obeticholic acid inhibits the reaction [TNF results in increased expression of SELP mRNA]]; NR1H4 gene mutant form inhibits the reaction [obeticholic acid results in increased expression of FABP6 mRNA]; NR1H4 gene mutant form inhibits the reaction [obeticholic acid results in increased expression of FGF15 mRNA]; NR1H4 promotes the reaction [obeticholic acid promotes the reaction [1-Naphthylisothiocyanate results in increased expression of ABCC2 mRNA]]; obeticholic acid binds to and results in increased activity of NR1H4 protein; obeticholic acid inhibits the reaction [1-Naphthylisothiocyanate results in decreased expression of NR1H4 mRNA]
obeticholic acid binds to and results in increased activity of NR1H4 protein; obeticholic acid promotes the reaction [NR1H4 protein binds to PRMT1 protein]
CTD PMID:15860571 PMID:15911693 PMID:15980055 PMID:17567710 PMID:21242261 PMID:22135065 PMID:22918042 PMID:27255380 PMID:27865854 PMID:27871908 PMID:28887089 PMID:29660435 PMID:32673658, PMID:27939985, PMID:15980055 RGD:15036816, RGD:1625201 NCBI chr12:100,473,866...100,564,414
Ensembl chr12:100,473,708...100,564,414
JBrowse link
G R Nr5a2 nuclear receptor subfamily 5, group A, member 2 decreases expression ISO obeticholic acid results in decreased expression of NR5A2 mRNA CTD PMID:27939613 NCBI chr13:53,750,470...53,870,288
Ensembl chr13:53,750,473...53,870,428
JBrowse link
G M Nr5a2 nuclear receptor subfamily 5, group A, member 2 decreases expression ISO obeticholic acid results in decreased expression of NR5A2 mRNA CTD PMID:27939613 NCBI chr 1:136,842,562...136,960,448
Ensembl chr 1:136,842,571...136,960,448
JBrowse link
G H NR5A2 nuclear receptor subfamily 5 group A member 2 decreases expression EXP obeticholic acid results in decreased expression of NR5A2 mRNA CTD PMID:27939613 NCBI chr 1:200,027,710...200,177,415
Ensembl chr 1:200,027,614...200,177,420
JBrowse link
G R P4hb prolyl 4-hydroxylase subunit beta increases expression ISO obeticholic acid results in increased expression of P4HB mRNA CTD PMID:27939613 NCBI chr10:109,736,459...109,748,070
Ensembl chr10:109,736,458...109,747,987
JBrowse link
G M P4hb prolyl 4-hydroxylase, beta polypeptide increases expression ISO obeticholic acid results in increased expression of P4HB mRNA CTD PMID:27939613 NCBI chr11:120,560,298...120,573,253
Ensembl chr11:120,560,298...120,573,253
JBrowse link
G H P4HB prolyl 4-hydroxylase subunit beta increases expression EXP obeticholic acid results in increased expression of P4HB mRNA CTD PMID:27939613 NCBI chr17:81,843,159...81,860,535
Ensembl chr17:81,843,161...81,860,624
Ensembl chr17:81,843,161...81,860,624
JBrowse link
G R Pc pyruvate carboxylase decreases expression ISO obeticholic acid results in decreased expression of PC mRNA CTD PMID:27939613 NCBI chr 1:219,759,157...219,859,854
Ensembl chr 1:219,759,183...219,859,848
JBrowse link
G H PC pyruvate carboxylase decreases expression EXP obeticholic acid results in decreased expression of PC mRNA CTD PMID:27939613 NCBI chr11:66,848,420...66,958,418
Ensembl chr11:66,848,417...66,958,386
JBrowse link
G R Pck1 phosphoenolpyruvate carboxykinase 1 decreases expression ISO obeticholic acid results in decreased expression of PCK1 mRNA CTD PMID:27939613 NCBI chr 3:171,213,936...171,219,885
Ensembl chr 3:171,213,936...171,219,871
JBrowse link
G M Pck1 phosphoenolpyruvate carboxykinase 1, cytosolic decreases expression ISO obeticholic acid results in decreased expression of PCK1 mRNA CTD PMID:27939613 NCBI chr 2:173,153,073...173,159,274
Ensembl chr 2:173,153,048...173,159,273
JBrowse link
G H PCK1 phosphoenolpyruvate carboxykinase 1 decreases expression EXP obeticholic acid results in decreased expression of PCK1 mRNA CTD PMID:27939613 NCBI chr20:57,561,110...57,568,121
Ensembl chr20:57,561,080...57,568,121
JBrowse link
G M Pcx pyruvate carboxylase decreases expression ISO obeticholic acid results in decreased expression of PC mRNA CTD PMID:27939613 NCBI chr19:4,510,472...4,621,752
Ensembl chr19:4,510,472...4,621,752
JBrowse link
G R Pfkfb1 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1 increases expression ISO obeticholic acid results in increased expression of PFKFB1 mRNA CTD PMID:27939613 NCBI chr  X:23,092,143...23,145,923
Ensembl chr  X:23,092,159...23,144,324
JBrowse link
G M Pfkfb1 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1 increases expression ISO obeticholic acid results in increased expression of PFKFB1 mRNA CTD PMID:27939613 NCBI chr  X:150,587,445...150,643,878
Ensembl chr  X:150,588,229...150,643,878
JBrowse link
G H PFKFB1 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1 increases expression EXP obeticholic acid results in increased expression of PFKFB1 mRNA CTD PMID:27939613 NCBI chr  X:54,932,961...55,000,052
Ensembl chr  X:54,932,961...54,998,534
JBrowse link
G R Pgm1 phosphoglucomutase 1 decreases expression ISO obeticholic acid results in decreased expression of PGM1 mRNA CTD PMID:27939613 NCBI chr 5:118,743,632...118,803,055
Ensembl chr 5:118,743,632...118,803,055
JBrowse link
G M Pgm1 phosphoglucomutase 1 decreases expression ISO obeticholic acid results in decreased expression of PGM1 mRNA CTD PMID:27939613 NCBI chr 4:99,929,451...99,987,294
Ensembl chr 4:99,929,414...99,987,294
JBrowse link
G H PGM1 phosphoglucomutase 1 decreases expression EXP obeticholic acid results in decreased expression of PGM1 mRNA CTD PMID:27939613 NCBI chr 1:63,593,411...63,660,245
Ensembl chr 1:63,593,411...63,660,245
JBrowse link
G R Pik3cd phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit delta decreases expression ISO obeticholic acid results in decreased expression of PIK3CD mRNA CTD PMID:27939613 NCBI chr 5:166,602,053...166,628,028
Ensembl chr 5:166,602,053...166,628,028
JBrowse link
G M Pik3cd phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta decreases expression ISO obeticholic acid results in decreased expression of PIK3CD mRNA CTD PMID:27939613 NCBI chr 4:149,649,168...149,702,566
Ensembl chr 4:149,649,168...149,702,571
JBrowse link
G H PIK3CD phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta decreases expression EXP obeticholic acid results in decreased expression of PIK3CD mRNA CTD PMID:27939613 NCBI chr 1:9,629,889...9,729,114
Ensembl chr 1:9,651,731...9,729,114
JBrowse link
G R Pik3r1 phosphoinositide-3-kinase regulatory subunit 1 decreases expression ISO obeticholic acid results in decreased expression of PIK3R1 mRNA CTD PMID:27939613 NCBI chr 2:31,742,326...31,826,882
Ensembl chr 2:31,745,088...31,826,867
JBrowse link
G M Pik3r1 phosphoinositide-3-kinase regulatory subunit 1 decreases expression ISO obeticholic acid results in decreased expression of PIK3R1 mRNA CTD PMID:27939613 NCBI chr13:101,680,761...101,768,217
Ensembl chr13:101,680,563...101,768,217
JBrowse link
G H PIK3R1 phosphoinositide-3-kinase regulatory subunit 1 decreases expression EXP obeticholic acid results in decreased expression of PIK3R1 mRNA CTD PMID:27939613 NCBI chr 5:68,215,737...68,301,821
Ensembl chr 5:68,215,756...68,301,821
JBrowse link
G H PKD1P1 polycystin 1, transient receptor potential channel interacting pseudogene 1 decreases expression EXP obeticholic acid results in decreased expression of PKD1P1 mRNA CTD PMID:27939613 NCBI chr16:16,317,609...16,350,608
Ensembl chr16:16,310,341...16,334,190
JBrowse link
G R Pltp phospholipid transfer protein decreases expression ISO obeticholic acid results in decreased expression of PLTP mRNA CTD PMID:27939613 NCBI chr 3:161,304,469...161,322,289
Ensembl chr 3:161,304,469...161,322,289
JBrowse link
G M Pltp phospholipid transfer protein decreases expression ISO obeticholic acid results in decreased expression of PLTP mRNA CTD PMID:27939613 NCBI chr 2:164,839,518...164,857,708
Ensembl chr 2:164,839,518...164,857,711
JBrowse link
G H PLTP phospholipid transfer protein decreases expression EXP obeticholic acid results in decreased expression of PLTP mRNA CTD PMID:27939613 NCBI chr20:45,898,620...45,912,155
Ensembl chr20:45,898,621...45,912,155
JBrowse link
G R Ppara peroxisome proliferator activated receptor alpha multiple interactions
increases expression
ISO
EXP
Palmitic Acid inhibits the reaction [obeticholic acid results in increased expression of PPARA mRNA]
Obeticholic acid inhibits the reaction [ethanol decreases expression of Ppara mRNA and protein in liver]
obeticholic acid inhibits the reaction [Ethanol results in decreased expression of PPARA protein]
obeticholic acid results in increased expression of PPARA mRNA; obeticholic acid results in increased expression of PPARA protein
CTD PMID:15980055 PMID:26655953 PMID:27939985, PMID:27939985 RGD:15036816 NCBI chr 7:126,618,872...126,687,282
Ensembl chr 7:126,619,196...126,681,752
JBrowse link
G M Ppara peroxisome proliferator activated receptor alpha multiple interactions
increases expression
EXP
ISO
Palmitic Acid inhibits the reaction [obeticholic acid results in increased expression of PPARA mRNA]
Obeticholic acid inhibits the reaction [ethanol decreases expression of Ppara mRNA and protein in liver]
obeticholic acid inhibits the reaction [Ethanol results in decreased expression of PPARA protein]
obeticholic acid results in increased expression of PPARA mRNA; obeticholic acid results in increased expression of PPARA protein
CTD PMID:15980055 PMID:26655953 PMID:27939985, PMID:27939985 RGD:15036816 NCBI chr15:85,734,910...85,806,851
Ensembl chr15:85,734,983...85,802,819
JBrowse link
G H PPARA peroxisome proliferator activated receptor alpha multiple interactions
increases expression
ISO
EXP
Palmitic Acid inhibits the reaction [obeticholic acid results in increased expression of PPARA mRNA]
Obeticholic acid inhibits the reaction [ethanol decreases expression of Ppara mRNA and protein in liver]
obeticholic acid inhibits the reaction [Ethanol results in decreased expression of PPARA protein]
obeticholic acid results in increased expression of PPARA mRNA; obeticholic acid results in increased expression of PPARA protein
CTD PMID:15980055 PMID:26655953 PMID:27939985, PMID:27939985 RGD:15036816 NCBI chr22:46,150,526...46,243,756
Ensembl chr22:46,150,521...46,243,756
JBrowse link
G R Pparg peroxisome proliferator-activated receptor gamma increases expression EXP obeticholic acid results in increased expression of PPARG mRNA; obeticholic acid results in increased expression of PPARG protein CTD PMID:15980055 NCBI chr 4:147,274,055...147,399,383
Ensembl chr 4:147,274,107...147,399,380
JBrowse link
G M Pparg peroxisome proliferator activated receptor gamma increases expression ISO obeticholic acid results in increased expression of PPARG mRNA; obeticholic acid results in increased expression of PPARG protein CTD PMID:15980055 NCBI chr 6:115,360,879...115,490,404
Ensembl chr 6:115,360,951...115,490,399
JBrowse link
G H PPARG peroxisome proliferator activated receptor gamma increases expression ISO obeticholic acid results in increased expression of PPARG mRNA; obeticholic acid results in increased expression of PPARG protein CTD PMID:15980055 NCBI chr 3:12,287,368...12,434,344
Ensembl chr 3:12,287,368...12,434,356
JBrowse link
G R Ppp1r3c protein phosphatase 1, regulatory subunit 3C decreases expression ISO obeticholic acid results in decreased expression of PPP1R3C mRNA CTD PMID:27939613 NCBI chr 1:255,371,830...255,376,833
Ensembl chr 1:255,371,810...255,376,833
JBrowse link
G M Ppp1r3c protein phosphatase 1, regulatory subunit 3C decreases expression ISO obeticholic acid results in decreased expression of PPP1R3C mRNA CTD PMID:27939613 NCBI chr19:36,731,731...36,736,604
Ensembl chr19:36,731,731...36,736,653
JBrowse link
G H PPP1R3C protein phosphatase 1 regulatory subunit 3C decreases expression EXP obeticholic acid results in decreased expression of PPP1R3C mRNA CTD PMID:27939613 NCBI chr10:91,628,442...91,633,071
Ensembl chr10:91,628,442...91,633,071
JBrowse link
G R Ppp2cb protein phosphatase 2 catalytic subunit beta increases expression ISO obeticholic acid results in increased expression of PPP2CB mRNA CTD PMID:27939613 NCBI chr16:62,273,276...62,294,767
Ensembl chr16:62,273,276...62,294,769
JBrowse link
G M Ppp2cb protein phosphatase 2 (formerly 2A), catalytic subunit, beta isoform increases expression ISO obeticholic acid results in increased expression of PPP2CB mRNA CTD PMID:27939613 NCBI chr 8:33,599,621...33,619,804
Ensembl chr 8:33,599,625...33,619,441
JBrowse link
G H PPP2CB protein phosphatase 2 catalytic subunit beta increases expression EXP obeticholic acid results in increased expression of PPP2CB mRNA CTD PMID:27939613 NCBI chr 8:30,785,616...30,812,818
Ensembl chr 8:30,774,457...30,814,314
JBrowse link
G R Ppp2r1b protein phosphatase 2 scaffold subunit A beta increases expression ISO obeticholic acid results in increased expression of PPP2R1B mRNA CTD PMID:27939613 NCBI chr 8:55,279,278...55,311,768
Ensembl chr 8:55,279,373...55,301,320
JBrowse link
G M Ppp2r1b protein phosphatase 2, regulatory subunit A, beta increases expression ISO obeticholic acid results in increased expression of PPP2R1B mRNA CTD PMID:27939613 NCBI chr 9:50,856,896...50,899,325
Ensembl chr 9:50,845,301...50,894,229
JBrowse link
G H PPP2R1B protein phosphatase 2 scaffold subunit Abeta increases expression EXP obeticholic acid results in increased expression of PPP2R1B mRNA CTD PMID:27939613 NCBI chr11:111,690,273...111,766,389
Ensembl chr11:111,726,908...111,766,389
JBrowse link
G R Prdx1 peroxiredoxin 1 decreases expression ISO obeticholic acid results in decreased expression of PRDX1 mRNA CTD PMID:27939613 NCBI chr 5:135,536,413...135,551,986
Ensembl chr 5:135,536,413...135,551,990
JBrowse link
G M Prdx1 peroxiredoxin 1 decreases expression ISO obeticholic acid results in decreased expression of PRDX1 mRNA CTD PMID:27939613 NCBI chr 4:116,685,599...116,700,000
Ensembl chr 4:116,685,544...116,700,822
JBrowse link
G H PRDX1 peroxiredoxin 1 decreases expression EXP obeticholic acid results in decreased expression of PRDX1 mRNA CTD PMID:27939613 NCBI chr 1:45,511,051...45,522,890
Ensembl chr 1:45,511,036...45,523,047
Ensembl chr 1:45,511,036...45,523,047
JBrowse link
G R Prdx6 peroxiredoxin 6 decreases expression ISO obeticholic acid results in decreased expression of PRDX6 mRNA CTD PMID:27939613 NCBI chr13:79,077,567...79,088,113
Ensembl chr13:79,077,033...79,088,127
JBrowse link
G M Prdx6 peroxiredoxin 6 decreases expression ISO obeticholic acid results in decreased expression of PRDX6 mRNA CTD PMID:27939613 NCBI chr 1:161,240,112...161,251,210
Ensembl chr 1:161,240,112...161,251,219
JBrowse link
G H PRDX6 peroxiredoxin 6 decreases expression EXP obeticholic acid results in decreased expression of PRDX6 mRNA CTD PMID:27939613 NCBI chr 1:173,477,335...173,488,815
Ensembl chr 1:173,477,330...173,488,815
JBrowse link
G R Prkca protein kinase C, alpha increases expression ISO obeticholic acid results in increased expression of PRKCA mRNA CTD PMID:27939613 NCBI chr10:96,186,509...96,585,168
Ensembl chr10:96,191,133...96,584,947
JBrowse link
G M Prkca protein kinase C, alpha increases expression ISO obeticholic acid results in increased expression of PRKCA mRNA CTD PMID:27939613 NCBI chr11:107,933,387...108,343,888
Ensembl chr11:107,933,387...108,343,928
JBrowse link
G H PRKCA protein kinase C alpha increases expression EXP obeticholic acid results in increased expression of PRKCA mRNA CTD PMID:27939613 NCBI chr17:66,302,613...66,810,743
Ensembl chr17:66,302,613...66,810,743
JBrowse link
G R Prkce protein kinase C, epsilon increases expression ISO obeticholic acid results in increased expression of PRKCE mRNA CTD PMID:27939613 NCBI chr 6:9,483,400...9,973,396
Ensembl chr 6:9,790,422...9,973,396
JBrowse link
G M Prkce protein kinase C, epsilon increases expression ISO obeticholic acid results in increased expression of PRKCE mRNA CTD PMID:27939613 NCBI chr17:86,167,785...86,657,919
Ensembl chr17:86,167,785...86,657,919
JBrowse link
G H PRKCE protein kinase C epsilon increases expression EXP obeticholic acid results in increased expression of PRKCE mRNA CTD PMID:27939613 NCBI chr 2:45,651,315...46,187,990
Ensembl chr 2:45,651,345...46,187,990
JBrowse link
G R Prmt1 protein arginine methyltransferase 1 multiple interactions
increases activity
ISO obeticholic acid promotes the reaction [NR1H4 protein binds to PRMT1 protein]; obeticholic acid promotes the reaction [PRMT1 protein binds to ABCB11 promoter]
obeticholic acid results in increased activity of PRMT1 protein
CTD PMID:15911693 NCBI chr 1:100,971,132...100,980,411
Ensembl chr 1:100,971,273...100,980,340
JBrowse link
G M Prmt1 protein arginine N-methyltransferase 1 multiple interactions
increases activity
ISO obeticholic acid promotes the reaction [NR1H4 protein binds to PRMT1 protein]; obeticholic acid promotes the reaction [PRMT1 protein binds to ABCB11 promoter]
obeticholic acid results in increased activity of PRMT1 protein
CTD PMID:15911693 NCBI chr 7:44,976,755...44,986,420
Ensembl chr 7:44,975,989...44,986,568
JBrowse link
G H PRMT1 protein arginine methyltransferase 1 multiple interactions
increases activity
EXP obeticholic acid promotes the reaction [NR1H4 protein binds to PRMT1 protein]; obeticholic acid promotes the reaction [PRMT1 protein binds to ABCB11 promoter]
obeticholic acid results in increased activity of PRMT1 protein
CTD PMID:15911693 NCBI chr19:49,676,166...49,688,447
Ensembl chr19:49,675,786...49,689,029
JBrowse link
G R Prmt2 protein arginine methyltransferase 2 multiple interactions ISO obeticholic acid promotes the reaction [PRMT2 protein binds to NR0B2 promoter] CTD PMID:15911693 NCBI chr20:13,154,513...13,212,613
Ensembl chr20:13,156,241...13,212,606
JBrowse link
G M Prmt2 protein arginine N-methyltransferase 2 multiple interactions ISO obeticholic acid promotes the reaction [PRMT2 protein binds to NR0B2 promoter] CTD PMID:15911693 NCBI chr10:76,207,226...76,237,865
Ensembl chr10:76,207,222...76,237,865
JBrowse link
G H PRMT2 protein arginine methyltransferase 2 multiple interactions EXP obeticholic acid promotes the reaction [PRMT2 protein binds to NR0B2 promoter] CTD PMID:15911693 NCBI chr21:46,635,156...46,665,685
Ensembl chr21:46,635,595...46,665,124
JBrowse link
G R Ptbp2 polypyrimidine tract binding protein 2 decreases expression ISO obeticholic acid results in decreased expression of PTBP2 mRNA CTD PMID:27939613 NCBI chr 2:223,261,444...223,323,075
Ensembl chr 2:223,262,852...223,322,585
JBrowse link
G M Ptbp2 polypyrimidine tract binding protein 2 decreases expression ISO obeticholic acid results in decreased expression of PTBP2 mRNA CTD PMID:27939613 NCBI chr 3:119,718,741...119,784,647
Ensembl chr 3:119,718,742...119,784,466
JBrowse link
G H PTBP2 polypyrimidine tract binding protein 2 decreases expression EXP obeticholic acid results in decreased expression of PTBP2 mRNA CTD PMID:27939613 NCBI chr 1:96,721,766...96,823,739
Ensembl chr 1:96,721,665...96,823,738
JBrowse link
G R Rela RELA proto-oncogene, NF-kB subunit multiple interactions ISO obeticholic acid inhibits the reaction [1-Naphthylisothiocyanate results in increased expression of RELA protein] CTD PMID:29660435 NCBI chr 1:220,992,770...221,003,249
Ensembl chr 1:220,992,770...221,003,249
JBrowse link
G M Rela v-rel reticuloendotheliosis viral oncogene homolog A (avian) multiple interactions EXP obeticholic acid inhibits the reaction [1-Naphthylisothiocyanate results in increased expression of RELA protein] CTD PMID:29660435 NCBI chr19:5,637,442...5,648,134
Ensembl chr19:5,637,483...5,648,130
JBrowse link
G H RELA RELA proto-oncogene, NF-kB subunit multiple interactions ISO obeticholic acid inhibits the reaction [1-Naphthylisothiocyanate results in increased expression of RELA protein] CTD PMID:29660435 NCBI chr11:65,653,601...65,662,946
Ensembl chr11:65,653,597...65,663,090
JBrowse link
G R Ros1 ROS proto-oncogene 1 , receptor tyrosine kinase increases expression ISO obeticholic acid results in increased expression of ROS1 mRNA CTD PMID:27939613 NCBI chr20:33,100,190...33,323,544
Ensembl chr20:33,100,191...33,323,367
JBrowse link
G M Ros1 Ros1 proto-oncogene increases expression ISO obeticholic acid results in increased expression of ROS1 mRNA CTD PMID:27939613 NCBI chr10:52,044,863...52,195,398
Ensembl chr10:52,045,721...52,195,244
JBrowse link
G H ROS1 ROS proto-oncogene 1, receptor tyrosine kinase increases expression EXP obeticholic acid results in increased expression of ROS1 mRNA CTD PMID:27939613 NCBI chr 6:117,287,353...117,426,065
Ensembl chr 6:117,288,300...117,425,855
Ensembl chr 6:117,288,300...117,425,855
JBrowse link
G R Rps6ka2 ribosomal protein S6 kinase A2 increases expression ISO obeticholic acid results in increased expression of RPS6KA2 mRNA CTD PMID:27939613 NCBI chr 1:53,219,346...53,499,445
Ensembl chr 1:53,360,157...53,499,445
JBrowse link
G M Rps6ka2 ribosomal protein S6 kinase, polypeptide 2 increases expression ISO obeticholic acid results in increased expression of RPS6KA2 mRNA CTD PMID:27939613 NCBI chr17:7,088,971...7,303,315
Ensembl chr17:7,170,115...7,303,315
JBrowse link
G H RPS6KA2 ribosomal protein S6 kinase A2 increases expression EXP obeticholic acid results in increased expression of RPS6KA2 mRNA CTD PMID:27939613 NCBI chr 6:166,409,364...166,862,525
Ensembl chr 6:166,409,364...166,906,451
JBrowse link
G R Rps6ka4 ribosomal protein S6 kinase A4 decreases expression ISO obeticholic acid results in decreased expression of RPS6KA4 mRNA CTD PMID:27939613 NCBI chr 1:222,087,328...222,098,284
Ensembl chr 1:222,087,326...222,098,297
JBrowse link
G M Rps6ka4 ribosomal protein S6 kinase, polypeptide 4 decreases expression ISO obeticholic acid results in decreased expression of RPS6KA4 mRNA CTD PMID:27939613 NCBI chr19:6,829,084...6,842,145
Ensembl chr19:6,829,085...6,840,636
JBrowse link
G H RPS6KA4 ribosomal protein S6 kinase A4 decreases expression EXP obeticholic acid results in decreased expression of RPS6KA4 mRNA CTD PMID:27939613 NCBI chr11:64,359,162...64,372,215
Ensembl chr11:64,359,148...64,372,215
JBrowse link
G R Rps6ka5 ribosomal protein S6 kinase A5 decreases expression ISO obeticholic acid results in decreased expression of RPS6KA5 mRNA CTD PMID:27939613 NCBI chr 6:124,557,892...124,735,787
Ensembl chr 6:124,557,913...124,735,778
JBrowse link
G M Rps6ka5 ribosomal protein S6 kinase, polypeptide 5 decreases expression ISO obeticholic acid results in decreased expression of RPS6KA5 mRNA CTD PMID:27939613 NCBI chr12:100,548,439...100,725,328
Ensembl chr12:100,548,439...100,726,983
JBrowse link
G H RPS6KA5 ribosomal protein S6 kinase A5 decreases expression EXP obeticholic acid results in decreased expression of RPS6KA5 mRNA CTD PMID:27939613 NCBI chr14:90,847,861...91,060,641
Ensembl chr14:90,847,861...91,060,641
JBrowse link
G R Rras2 RAS related 2 increases expression ISO obeticholic acid results in increased expression of RRAS2 mRNA CTD PMID:27939613 NCBI chr 1:178,940,515...179,010,257
Ensembl chr 1:178,940,516...179,010,257
JBrowse link
G M Rras2 related RAS viral (r-ras) oncogene 2 increases expression ISO obeticholic acid results in increased expression of RRAS2 mRNA CTD PMID:27939613 NCBI chr 7:114,046,782...114,117,781
Ensembl chr 7:114,046,782...114,117,781
JBrowse link
G H RRAS2 RAS related 2 increases expression EXP obeticholic acid results in increased expression of RRAS2 mRNA CTD PMID:27939613 NCBI chr11:14,277,920...14,364,506
Ensembl chr11:14,277,922...14,364,506
JBrowse link
G R Rtp3 receptor (chemosensory) transporter protein 3 increases expression ISO obeticholic acid results in increased expression of RTP3 mRNA CTD PMID:27939613 NCBI chr 8:119,260,609...119,265,501
Ensembl chr 8:119,260,618...119,265,157
JBrowse link
G M Rtp3 receptor transporter protein 3 increases expression ISO obeticholic acid results in increased expression of RTP3 mRNA CTD PMID:27939613 NCBI chr 9:110,984,935...110,990,265
Ensembl chr 9:110,984,935...110,990,583
JBrowse link
G H RTP3 receptor transporter protein 3 increases expression EXP obeticholic acid results in increased expression of RTP3 mRNA CTD PMID:27939613 NCBI chr 3:46,497,976...46,500,950
Ensembl chr 3:46,497,976...46,500,950
JBrowse link
G R Rxra retinoid X receptor alpha decreases expression ISO obeticholic acid results in decreased expression of RXRA mRNA CTD PMID:27939613 NCBI chr 3:6,272,560...6,295,354
Ensembl chr 3:6,211,789...6,295,908
JBrowse link
G M Rxra retinoid X receptor alpha decreases expression ISO obeticholic acid results in decreased expression of RXRA mRNA CTD PMID:27939613 NCBI chr 2:27,676,445...27,763,319
Ensembl chr 2:27,676,440...27,762,957
JBrowse link
G H RXRA retinoid X receptor alpha decreases expression EXP obeticholic acid results in decreased expression of RXRA mRNA CTD PMID:27939613 NCBI chr 9:134,326,455...134,440,585
Ensembl chr 9:134,317,098...134,440,585
JBrowse link
G R S100a3 S100 calcium binding protein A3 decreases expression ISO obeticholic acid results in decreased expression of S100A3 mRNA CTD PMID:27939613 NCBI chr 2:189,955,619...189,996,029
Ensembl chr 2:189,955,836...189,996,029
JBrowse link
G M S100a3 S100 calcium binding protein A3 decreases expression ISO obeticholic acid results in decreased expression of S100A3 mRNA CTD PMID:27939613 NCBI chr 3:90,560,356...90,602,706
Ensembl chr 3:90,584,659...90,602,702
JBrowse link
G H S100A3 S100 calcium binding protein A3 decreases expression EXP obeticholic acid results in decreased expression of S100A3 mRNA CTD PMID:27939613 NCBI chr 1:153,547,329...153,549,258
Ensembl chr 1:153,547,329...153,549,258
JBrowse link
G M Saa1 serum amyloid A 1 increases expression ISO obeticholic acid results in increased expression of SAA1 mRNA CTD PMID:27939613 NCBI chr 7:46,740,497...46,743,181
Ensembl chr 7:46,740,497...46,742,980
JBrowse link
G H SAA1 serum amyloid A1 increases expression EXP obeticholic acid results in increased expression of SAA1 mRNA CTD PMID:27939613 NCBI chr11:18,266,264...18,269,967
Ensembl chr11:18,266,260...18,269,977
JBrowse link
G R Sc5d sterol-C5-desaturase decreases expression ISO obeticholic acid results in decreased expression of SC5D mRNA CTD PMID:27939613 NCBI chr 8:46,525,406...46,537,014
Ensembl chr 8:46,525,400...46,537,050
JBrowse link
G M Sc5d sterol-C5-desaturase decreases expression ISO obeticholic acid results in decreased expression of SC5D mRNA CTD PMID:27939613 NCBI chr 9:42,251,592...42,264,300
Ensembl chr 9:42,251,595...42,264,256
JBrowse link
G H SC5D sterol-C5-desaturase decreases expression EXP obeticholic acid results in decreased expression of SC5D mRNA CTD PMID:27939613 NCBI chr11:121,292,771...121,313,410
Ensembl chr11:121,292,681...121,313,410
JBrowse link
G R Scarb1 scavenger receptor class B, member 1 increases expression ISO obeticholic acid results in increased expression of SCARB1 mRNA CTD PMID:27939613 NCBI chr12:36,694,952...36,761,445
Ensembl chr12:36,694,960...36,761,455
JBrowse link
G M Scarb1 scavenger receptor class B, member 1 increases expression ISO obeticholic acid results in increased expression of SCARB1 mRNA CTD PMID:27939613 NCBI chr 5:125,277,087...125,341,094
Ensembl chr 5:125,277,087...125,341,094
JBrowse link
G H SCARB1 scavenger receptor class B member 1 increases expression EXP obeticholic acid results in increased expression of SCARB1 mRNA CTD PMID:27939613 NCBI chr12:124,776,856...124,863,864
Ensembl chr12:124,776,856...124,882,668
JBrowse link
G R Sdc1 syndecan 1 increases expression ISO obeticholic acid results in increased expression of SDC1 mRNA CTD PMID:27939613 NCBI chr 6:33,885,576...33,908,038
Ensembl chr 6:33,885,495...33,908,016
JBrowse link
G M Sdc1 syndecan 1 increases expression ISO obeticholic acid results in increased expression of SDC1 mRNA CTD