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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:3-(1H-indol-3-yl)propanoic acid
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Accession:CHEBI:43580 term browser browse the term
Definition:An indol-3-yl carboxylic acid that is propionic acid substituted by a 1H-indol-3-yl group at position 3.
Synonyms:related_synonym: Formula=C11H11NO2;   InChI=1S/C11H11NO2/c13-11(14)6-5-8-7-12-10-4-2-1-3-9(8)10/h1-4,7,12H,5-6H2,(H,13,14);   InChIKey=GOLXRNDWAUTYKT-UHFFFAOYSA-N;   Indole-3-propionic acid;   Indolepropionic acid;   SMILES=OC(=O)CCc1c[nH]c2ccccc12;   beta-(3-Indolyl)propionic acid
 xref: CAS:830-96-6;   HMDB:HMDB0002302
 xref_mesh: MESH:C015292
 xref: PDBeChem:IOP;   PMID:12212784;   PMID:14606996;   PMID:21307383;   PMID:22885049;   PMID:24510403;   Reaxys:147733
 cyclic_relationship: is_conjugate_acid_of CHEBI:82916



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3-(1H-indol-3-yl)propanoic acid term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ahr aryl hydrocarbon receptor multiple interactions ISO 3-(1H-indol-3-yl)propanoic acid inhibits the reaction [indoxyl sulfate increases expression of mRNA, protein] in HK-2 human kidney proximal tubule cell line RGD PMID:29238104 RGD:401793752 NCBI chr 6:52,234,089...52,271,568
Ensembl chr 6:52,234,089...52,271,568
JBrowse link
G Ccl2 C-C motif chemokine ligand 2 multiple interactions ISO 3-(1H-indol-3-yl)propanoic acid inhibits the reaction [indoxyl sulfate increases expression of mRNA, protein] in HK-2 human kidney proximal tubule cell line RGD PMID:29238104 RGD:401793752 NCBI chr10:67,005,424...67,007,222
Ensembl chr10:67,005,424...67,007,226
JBrowse link
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 multiple interactions ISO 3-(1H-indol-3-yl)propanoic acid inhibits the reaction [indoxyl sulfate increases expression of mRNA, protein] in HK-2 human kidney proximal tubule cell line RGD PMID:29238104 RGD:401793752 NCBI chr 8:58,096,021...58,102,130
Ensembl chr 8:58,096,077...58,102,125
JBrowse link
G Nfkbia NFKB inhibitor alpha increases expression ISO indolepropionic acid analog results in increased expression of NFKBIA protein CTD PMID:23499788 NCBI chr 6:72,858,713...72,861,941
Ensembl chr 6:72,858,712...72,861,941
JBrowse link
G Parp1 poly (ADP-ribose) polymerase 1 increases cleavage ISO indolepropionic acid analog results in increased cleavage of PARP1 protein CTD PMID:23499788 NCBI chr13:92,307,593...92,339,406
Ensembl chr13:92,307,586...92,339,404
JBrowse link
G Stat3 signal transducer and activator of transcription 3 multiple interactions ISO 3-(1H-indol-3-yl)propanoic acid inhibits the reaction [indoxyl sulfate increases expression and increases phosphorylation of Stat3] in HK-2 human kidney proximal tubule cell line RGD PMID:29238104 RGD:401793752 NCBI chr10:85,811,206...85,863,057
Ensembl chr10:85,811,218...85,863,057
JBrowse link
G Tgfb1 transforming growth factor, beta 1 multiple interactions ISO 3-(1H-indol-3-yl)propanoic acid inhibits the reaction [indoxyl sulfate increases expression of mRNA, protein] in HK-2 human kidney proximal tubule cell line RGD PMID:29238104 RGD:401793752 NCBI chr 1:81,196,532...81,212,848
Ensembl chr 1:81,196,532...81,212,847
JBrowse link

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  CHEBI ontology 19918
    role 19894
      biological role 19892
        molecular messenger 18682
          hormone 18528
            plant hormone 8848
              auxin 1508
                3-(1H-indol-3-yl)propanoic acid 7
Path 2
Term Annotations click to browse term
  CHEBI ontology 19918
    subatomic particle 19916
      composite particle 19916
        hadron 19916
          baryon 19916
            nucleon 19916
              atomic nucleus 19916
                atom 19916
                  main group element atom 19866
                    p-block element atom 19866
                      carbon group element atom 19811
                        carbon atom 19806
                          organic molecular entity 19806
                            organic group 18995
                              organic divalent group 18969
                                organodiyl group 18969
                                  carbonyl group 18922
                                    carbonyl compound 18922
                                      carboxylic acid 18646
                                        monocarboxylic acid 17984
                                          fatty acid 16709
                                            saturated fatty acid 16409
                                              propionic acid 3808
                                                3-(1H-indol-3-yl)propanoic acid 7
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