Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   


Term:3-[isopropyl(4-methylbenzoyl)amino]-5-phenylthiophene-2-carboxylic acid
go back to main search page
Accession:CHEBI:43541 term browser browse the term
Definition:An amido thiophene-2-carboxylic acid derivative used as an inhibitor of HCV (Hepatitis C Virus) RNA polymerase.
Synonyms:exact_synonym: 3-[(4-methylbenzoyl)(propan-2-yl)amino]-5-phenylthiophene-2-carboxylic acid
 related_synonym: 3-[Isopropyl-(4-methyl-benzoyl)-amino]-5-phenyl-thiophene-2-carboxylic acid;   Formula=C22H21NO3S;   InChI=1S/C22H21NO3S/c1-14(2)23(21(24)17-11-9-15(3)10-12-17)18-13-19(27-20(18)22(25)26)16-7-5-4-6-8-16/h4-14H,1-3H3,(H,25,26);   InChIKey=LRHXIDOGMBZJFN-UHFFFAOYSA-N;   SMILES=CC(C)N(C(=O)c1ccc(C)cc1)c1cc(sc1C(O)=O)-c1ccccc1
 alt_id: CHEBI:36784;   CHEBI:377577;   CHEBI:43539
 xref: Beilstein:9651127 "Beilstein";   DrugBank:DB03647;   PDBeChem:IPC;   PMID:14741292 "ChEMBL";   PMID:15746101 "Europe PMC"

show annotations for term's descendants       view all columns           Sort by:

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19669
    chemical entity 19667
      atom 19665
        nonmetal atom 19531
          sulfur atom 15983
            sulfur molecular entity 15983
              organosulfur compound 14804
                organosulfur heterocyclic compound 5248
                  thiophenes 178
                    3-[isopropyl(4-methylbenzoyl)amino]-5-phenylthiophene-2-carboxylic acid 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 19669
    subatomic particle 19665
      composite particle 19665
        hadron 19665
          baryon 19665
            nucleon 19665
              atomic nucleus 19665
                atom 19665
                  main group element atom 19545
                    p-block element atom 19545
                      carbon group element atom 19428
                        carbon atom 19420
                          organic molecular entity 19420
                            organic group 18343
                              organic divalent group 18334
                                organodiyl group 18334
                                  carbonyl group 18222
                                    carbonyl compound 18222
                                      carboxylic acid 17923
                                        carboacyl group 16943
                                          univalent carboacyl group 16943
                                            carbamoyl group 16622
                                              carboxamide 16622
                                                monocarboxylic acid amide 13180
                                                  3-[isopropyl(4-methylbenzoyl)amino]-5-phenylthiophene-2-carboxylic acid 0
paths to the root


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.