Send us a Message



Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   

CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:indoline
go back to main search page
Accession:CHEBI:43295 term browser browse the term
Definition:An indole that has formula C8H9N.
Synonyms:related_synonym: 2,3-dihydro-1H-indole;   Formula=C8H9N;   InChI=1S/C8H9N/c1-2-4-8-7(3-1)5-6-9-8/h1-4,9H,5-6H2;   InChIKey=LPAGFVYQRIESJQ-UHFFFAOYSA-N;   SMILES=C1Cc2ccccc2N1;   dihydroindole
 alt_id: CHEBI:33071;   CHEBI:43292;   CHEBI:471711
 xref: Beilstein:111915;   CAS:496-15-1;   Gmelin:27284
 xref_mesh: MESH:C057812
 xref: PDBeChem:IDM;   PMID:17378546



show annotations for term's descendants           Sort by:
indoline term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acsl4 acyl-CoA synthetase long-chain family member 4 multiple interactions ISO [Thiazoles binds to indoline] promotes the reaction [1,3-dichloro-2-propanol results in increased expression of ACSL4 protein] CTD PMID:35870111 NCBI chr  X:105,942,794...106,006,573
Ensembl chr  X:105,942,799...106,006,427
JBrowse link
G Cyp3a2 cytochrome P450, family 3, subfamily a, polypeptide 2 increases metabolic processing ISO CYP3A4 protein results in increased metabolism of indoline CTD PMID:17502430 NCBI chr12:9,207,978...9,230,064
Ensembl chr12:9,015,383...9,285,008
JBrowse link
G Fth1 ferritin heavy chain 1 multiple interactions ISO [Thiazoles binds to indoline] promotes the reaction [1,3-dichloro-2-propanol results in decreased expression of FTH1 protein] CTD PMID:35870111 NCBI chr 1:206,627,142...206,629,430
Ensembl chr 1:206,627,103...206,725,424
JBrowse link
G Gpx4 glutathione peroxidase 4 multiple interactions ISO [Thiazoles binds to indoline] promotes the reaction [1,3-dichloro-2-propanol results in decreased expression of GPX4 protein] CTD PMID:35870111 NCBI chr 7:9,650,186...9,652,982
Ensembl chr 7:9,650,185...9,652,982
JBrowse link
G Hmox1 heme oxygenase 1 multiple interactions ISO [Thiazoles binds to indoline] promotes the reaction [1,3-dichloro-2-propanol results in decreased expression of HMOX1 protein] CTD PMID:35870111 NCBI chr19:13,466,287...13,474,082
Ensembl chr19:13,467,244...13,474,079
JBrowse link
G Il1b interleukin 1 beta multiple interactions EXP [Thiazoles analog binds to indoline analog] promotes the reaction [PHLDA3 protein promotes the reaction [[Oxygen deficiency co-treated with Oxygen] results in increased expression of IL1B protein]] CTD PMID:34351043 NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415
JBrowse link
G Il6 interleukin 6 multiple interactions EXP [Thiazoles analog binds to indoline analog] promotes the reaction [PHLDA3 protein promotes the reaction [[Oxygen deficiency co-treated with Oxygen] results in increased expression of IL6 protein]] CTD PMID:34351043 NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178
JBrowse link
G Nfe2l2 NFE2 like bZIP transcription factor 2 multiple interactions EXP [Thiazoles analog binds to indoline analog] inhibits the reaction [SESN2 protein promotes the reaction [Hydrogen Peroxide results in increased activity of NFE2L2 protein]]; [Thiazoles analog binds to indoline analog] promotes the reaction [PHLDA3 protein inhibits the reaction [[Oxygen deficiency co-treated with Oxygen] results in increased expression of and affects the localization of and results in increased activity of NFE2L2 protein]]; [Thiazoles analog binds to indoline analog] which results in decreased activity of NFE2L2 protein CTD PMID:32275923 PMID:34351043 NCBI chr 3:60,594,239...60,621,712
Ensembl chr 3:60,594,242...60,621,737
JBrowse link
G Phlda3 pleckstrin homology-like domain, family A, member 3 multiple interactions EXP [Thiazoles analog binds to indoline analog] promotes the reaction [PHLDA3 protein inhibits the reaction [[Oxygen deficiency co-treated with Oxygen] results in increased expression of and affects the localization of and results in increased activity of NFE2L2 protein]]; [Thiazoles analog binds to indoline analog] promotes the reaction [PHLDA3 protein promotes the reaction [[Oxygen deficiency co-treated with Oxygen] results in increased expression of IL1B protein]]; [Thiazoles analog binds to indoline analog] promotes the reaction [PHLDA3 protein promotes the reaction [[Oxygen deficiency co-treated with Oxygen] results in increased expression of IL6 protein]]; [Thiazoles analog binds to indoline analog] promotes the reaction [PHLDA3 protein promotes the reaction [[Oxygen deficiency co-treated with Oxygen] results in increased expression of TNF protein]] CTD PMID:34351043 NCBI chr13:47,193,250...47,196,335
Ensembl chr13:47,193,086...47,196,335
JBrowse link
G Sesn2 sestrin 2 multiple interactions EXP [Thiazoles analog binds to indoline analog] inhibits the reaction [SESN2 protein promotes the reaction [Hydrogen Peroxide results in increased activity of NFE2L2 protein]] CTD PMID:32275923 NCBI chr 5:144,702,287...144,721,241
Ensembl chr 5:144,701,530...144,721,260
JBrowse link
G Slc40a1 solute carrier family 40 member 1 multiple interactions ISO [Thiazoles binds to indoline] promotes the reaction [1,3-dichloro-2-propanol results in decreased expression of SLC40A1 protein] CTD PMID:35870111 NCBI chr 9:48,033,526...48,053,876
Ensembl chr 9:48,033,526...48,051,481
JBrowse link
G Slc7a11 solute carrier family 7 member 11 multiple interactions ISO [Thiazoles binds to indoline] promotes the reaction [1,3-dichloro-2-propanol results in decreased expression of SLC7A11 protein] CTD PMID:35870111 NCBI chr 2:134,382,002...134,517,622
Ensembl chr 2:133,963,107...134,517,536
JBrowse link
G Tnf tumor necrosis factor multiple interactions EXP [Thiazoles analog binds to indoline analog] promotes the reaction [PHLDA3 protein promotes the reaction [[Oxygen deficiency co-treated with Oxygen] results in increased expression of TNF protein]] CTD PMID:34351043 NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19811
    chemical entity 19840
      atom 19809
        nonmetal atom 19747
          nitrogen atom 18962
            nitrogen molecular entity 18934
              organonitrogen compound 18783
                organonitrogen heterocyclic compound 18154
                  benzopyrrole 9716
                    indoles 9414
                      indoline 13
                        3,5,6-trihydroxyindoline 0
                        leukoaminochrome 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 19811
    subatomic particle 19809
      composite particle 19809
        hadron 19840
          baryon 19809
            nucleon 19809
              atomic nucleus 19809
                atom 19809
                  main group element atom 19759
                    p-block element atom 19759
                      carbon group element atom 19708
                        carbon atom 19734
                          organic molecular entity 19705
                            organic molecule 19658
                              organic cyclic compound 19471
                                organic heterocyclic compound 18862
                                  organic heteropolycyclic compound 18301
                                    organic heterobicyclic compound 17233
                                      benzopyrrole 9716
                                        indoles 9414
                                          indoline 13
                                            3,5,6-trihydroxyindoline 0
                                            leukoaminochrome 0
paths to the root