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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:heptane
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Accession:CHEBI:43098 term browser browse the term
Definition:A straight-chain alkane with seven carbon atoms. It has been found in Jeffrey pine (Pinus jeffreyi).
Synonyms:related_synonym: CH3-[CH2]5-CH3;   Formula=C7H16;   Heptan;   InChI=1S/C7H16/c1-3-5-7-6-4-2/h3-7H2,1-2H3;   InChIKey=IMNFDUFMRHMDMM-UHFFFAOYSA-N;   SMILES=CCCCCCC;   n-heptane
 alt_id: CHEBI:32891;   CHEBI:43095
 xref: Beilstein:1730763;   CAS:142-82-5;   Gmelin:49760;   HMDB:HMDB0031447;   MetaCyc:CPD-9286;   PDBeChem:HP6;   PMID:12226360;   PMID:23544797;   Wikipedia:Heptane



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1-heptanol term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cftr CF transmembrane conductance regulator increases activity ISO Heptanol results in increased activity of CFTR protein CTD PMID:14967738 NCBI chr 4:46,561,269...46,728,759
Ensembl chr 4:46,560,885...46,728,756
JBrowse link
G Gja1 gap junction protein, alpha 1 decreases phosphorylation EXP Heptanol results in decreased phosphorylation of GJA1 protein CTD PMID:16563290 NCBI chr20:35,756,007...35,768,481
Ensembl chr20:35,755,991...35,768,582
JBrowse link
perfluoroheptanoic acid term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcb4 ATP binding cassette subfamily B member 4 increases expression ISO perfluoro-n-heptanoic acid results in increased expression of ABCB4 mRNA CTD PMID:23567314 NCBI chr 4:25,150,998...25,209,489
Ensembl chr 4:25,151,953...25,209,202
JBrowse link
G Acsl1 acyl-CoA synthetase long-chain family member 1 increases expression ISO perfluoro-n-heptanoic acid results in increased expression of ACSL1 mRNA CTD PMID:23567314 NCBI chr16:45,755,246...45,821,541
Ensembl chr16:45,755,254...45,821,541
JBrowse link
G Akt1 AKT serine/threonine kinase 1 increases phosphorylation EXP perfluoro-n-heptanoic acid results in increased phosphorylation of AKT1 protein CTD PMID:33220336 NCBI chr 6:131,713,716...131,735,319
Ensembl chr 6:131,713,720...131,733,921
JBrowse link
G Akt2 AKT serine/threonine kinase 2 increases phosphorylation EXP perfluoro-n-heptanoic acid results in increased phosphorylation of AKT2 protein CTD PMID:33220336 NCBI chr 1:82,877,228...82,933,828
Ensembl chr 1:82,883,547...82,933,817
JBrowse link
G Angptl4 angiopoietin-like 4 increases expression ISO perfluoro-n-heptanoic acid results in increased expression of ANGPTL4 mRNA CTD PMID:23567314 NCBI chr 7:14,550,288...14,557,797
Ensembl chr 7:14,550,311...14,556,519
JBrowse link
G Apoa2 apolipoprotein A2 increases expression ISO perfluoro-n-heptanoic acid results in increased expression of APOA2 mRNA CTD PMID:23567314 NCBI chr13:83,644,460...83,646,358
Ensembl chr13:83,644,470...83,646,355
JBrowse link
G Apoa5 apolipoprotein A5 increases expression ISO perfluoro-n-heptanoic acid results in increased expression of APOA5 mRNA CTD PMID:23567314 NCBI chr 8:46,561,180...46,563,818
Ensembl chr 8:46,561,229...46,563,816
JBrowse link
G Bax BCL2 associated X, apoptosis regulator decreases expression EXP perfluoro-n-heptanoic acid results in decreased expression of BAX protein CTD PMID:33220336 NCBI chr 1:95,940,001...95,945,407
Ensembl chr 1:95,938,808...95,945,368
JBrowse link
G Bcl2 BCL2, apoptosis regulator increases expression EXP perfluoro-n-heptanoic acid results in increased expression of BCL2 protein CTD PMID:33220336 NCBI chr13:22,689,783...22,853,920 JBrowse link
G Ccnd1 cyclin D1 decreases expression ISO perfluoro-n-heptanoic acid results in decreased expression of CCND1 mRNA CTD PMID:23567314 NCBI chr 1:200,089,002...200,098,524
Ensembl chr 1:200,089,002...200,098,602
JBrowse link
G Cdh5 cadherin 5 affects expression ISO perfluoro-n-heptanoic acid affects the expression of CDH5 protein CTD PMID:33677611 NCBI chr19:815,415...854,478
Ensembl chr19:815,411...854,368
JBrowse link
G Cpt1a carnitine palmitoyltransferase 1A affects expression ISO perfluoro-n-heptanoic acid affects the expression of CPT1A mRNA CTD PMID:23567314 NCBI chr 1:200,564,634...200,627,059
Ensembl chr 1:200,565,613...200,627,055
JBrowse link
G Cpt1b carnitine palmitoyltransferase 1B affects expression ISO perfluoro-n-heptanoic acid affects the expression of CPT1B mRNA CTD PMID:23567314 NCBI chr 7:120,491,354...120,500,833
Ensembl chr 7:120,491,354...120,500,404
JBrowse link
G Cyp11a1 cytochrome P450, family 11, subfamily a, polypeptide 1 decreases expression EXP perfluoro-n-heptanoic acid results in decreased expression of CYP11A1 mRNA CTD PMID:33220336 NCBI chr 8:58,422,807...58,434,342
Ensembl chr 8:58,404,669...58,434,338
JBrowse link
G Cyp2b1 cytochrome P450, family 2, subfamily b, polypeptide 1 decreases expression ISO perfluoro-n-heptanoic acid results in decreased expression of CYP2B10 mRNA CTD PMID:23567314 NCBI chr 1:81,518,387...81,544,999
Ensembl chr 1:81,518,408...81,542,052
JBrowse link
G Cyp2b3 cytochrome P450, family 2, subfamily b, polypeptide 3 increases expression ISO perfluoro-n-heptanoic acid results in increased expression of CYP2B6 mRNA CTD PMID:23567314 NCBI chr 1:81,652,762...81,732,153
Ensembl chr 1:81,652,787...81,732,143
JBrowse link
G Cyp2c6v1 cytochrome P450, family 2, subfamily C, polypeptide 6, variant 1 decreases activity ISO perfluoro-n-heptanoic acid results in decreased activity of CYP2C19 protein CTD PMID:35121066 NCBI chr 1:237,938,521...237,976,238
Ensembl chr 1:237,693,094...238,057,596
JBrowse link
G Cyp2d4 cytochrome P450, family 2, subfamily d, polypeptide 4 decreases activity ISO perfluoro-n-heptanoic acid results in decreased activity of CYP2D6 protein CTD PMID:35121066 NCBI chr 7:113,882,584...113,891,754
Ensembl chr 7:113,881,618...113,891,759
JBrowse link
G Cyp3a2 cytochrome P450, family 3, subfamily a, polypeptide 2 increases expression ISO perfluoro-n-heptanoic acid results in increased expression of CYP3A4 mRNA CTD PMID:23567314 NCBI chr12:9,207,986...9,230,038
Ensembl chr12:9,015,383...9,285,008
JBrowse link
G Ehhadh enoyl-CoA hydratase and 3-hydroxyacyl CoA dehydrogenase increases expression ISO perfluoro-n-heptanoic acid results in increased expression of EHHADH mRNA CTD PMID:23567314 NCBI chr11:79,241,927...79,275,173
Ensembl chr11:79,241,938...79,275,188
JBrowse link
G Fabp1 fatty acid binding protein 1 increases expression ISO perfluoro-n-heptanoic acid results in increased expression of FABP1 mRNA CTD PMID:23567314 NCBI chr 4:103,191,015...103,194,791
Ensembl chr 4:103,191,006...103,194,788
JBrowse link
G Fshb follicle stimulating hormone subunit beta increases expression EXP perfluoro-n-heptanoic acid results in increased expression of FSHB protein CTD PMID:33220336 NCBI chr 3:93,548,560...93,552,370
Ensembl chr 3:93,548,560...93,552,370
JBrowse link
G Fshr follicle stimulating hormone receptor increases expression EXP perfluoro-n-heptanoic acid results in increased expression of FSHR mRNA; perfluoro-n-heptanoic acid results in increased expression of FSHR protein CTD PMID:33220336 NCBI chr 6:5,198,825...5,406,785
Ensembl chr 6:5,198,825...5,406,785
JBrowse link
G Gadd45b growth arrest and DNA-damage-inducible, beta decreases expression ISO perfluoro-n-heptanoic acid results in decreased expression of GADD45B mRNA CTD PMID:23567314 NCBI chr 7:8,778,004...8,780,306
Ensembl chr 7:8,778,007...8,780,046
JBrowse link
G Hadha hydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit alpha increases expression ISO perfluoro-n-heptanoic acid results in increased expression of HADHA mRNA CTD PMID:23567314 NCBI chr 6:26,187,969...26,227,605
Ensembl chr 6:26,187,956...26,227,869
JBrowse link
G Hmgcs2 3-hydroxy-3-methylglutaryl-CoA synthase 2 increases expression ISO perfluoro-n-heptanoic acid results in increased expression of HMGCS2 mRNA CTD PMID:23567314 NCBI chr 2:185,875,609...185,903,505
Ensembl chr 2:185,875,616...185,902,130
JBrowse link
G Hsd17b3 hydroxysteroid (17-beta) dehydrogenase 3 decreases expression EXP perfluoro-n-heptanoic acid results in decreased expression of HSD17B3 mRNA CTD PMID:33220336 NCBI chr17:1,027,229...1,058,554
Ensembl chr17:1,027,229...1,058,554
JBrowse link
G Hsd17b4 hydroxysteroid (17-beta) dehydrogenase 4 increases expression ISO perfluoro-n-heptanoic acid results in increased expression of HSD17B4 mRNA CTD PMID:23567314 NCBI chr18:43,328,903...43,417,950
Ensembl chr18:43,328,824...43,417,952
JBrowse link
G Hsd3b1 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1 increases expression EXP perfluoro-n-heptanoic acid results in increased expression of HSD3B1 protein CTD PMID:33220336 NCBI chr 2:186,169,864...186,175,984
Ensembl chr 2:186,169,863...186,175,999
JBrowse link
G Insl3 insulin-like 3 increases expression EXP perfluoro-n-heptanoic acid results in increased expression of INSL3 protein CTD PMID:33220336 NCBI chr16:18,398,682...18,400,566
Ensembl chr16:18,384,829...18,400,560
JBrowse link
G Itga1 integrin subunit alpha 1 affects expression ISO perfluoro-n-heptanoic acid affects the expression of ITGA1 protein CTD PMID:33677611 NCBI chr 2:46,646,125...46,812,237
Ensembl chr 2:46,653,193...46,812,238
JBrowse link
G Lhb luteinizing hormone subunit beta increases expression EXP perfluoro-n-heptanoic acid results in increased expression of LHB protein CTD PMID:33220336 NCBI chr 1:95,898,269...95,901,973
Ensembl chr 1:95,900,984...95,901,972
Ensembl chr 1:95,900,984...95,901,972
JBrowse link
G Mapk1 mitogen activated protein kinase 1 increases phosphorylation EXP perfluoro-n-heptanoic acid results in increased phosphorylation of MAPK1 protein CTD PMID:33220336 NCBI chr11:83,957,813...84,023,629
Ensembl chr11:83,957,813...84,023,616
JBrowse link
G Mapk3 mitogen activated protein kinase 3 increases phosphorylation EXP perfluoro-n-heptanoic acid results in increased phosphorylation of MAPK3 protein CTD PMID:33220336 NCBI chr 1:181,366,646...181,372,863
Ensembl chr 1:181,366,637...181,372,863
JBrowse link
G Mbl2 mannose binding lectin 2 increases expression ISO perfluoro-n-heptanoic acid results in increased expression of MBL2 mRNA CTD PMID:23567314 NCBI chr 1:228,016,439...228,024,736 JBrowse link
G Mogat1 monoacylglycerol O-acyltransferase 1 increases expression ISO perfluoro-n-heptanoic acid results in increased expression of MOGAT1 mRNA CTD PMID:23567314 NCBI chr 9:79,980,963...79,988,513
Ensembl chr 9:79,956,649...79,988,513
JBrowse link
G Nr1i2 nuclear receptor subfamily 1, group I, member 2 increases activity ISO perfluoro-n-heptanoic acid results in increased activity of NR1I2 protein CTD PMID:28115241 NCBI chr11:62,460,213...62,496,665
Ensembl chr11:62,460,213...62,496,658
JBrowse link
G Pdk4 pyruvate dehydrogenase kinase 4 increases expression ISO perfluoro-n-heptanoic acid results in increased expression of PDK4 mRNA CTD PMID:23567314 NCBI chr 4:33,591,796...33,601,798
Ensembl chr 4:33,589,799...33,601,850
JBrowse link
G Plin2 perilipin 2 increases expression ISO perfluoro-n-heptanoic acid results in increased expression of PLIN2 mRNA CTD PMID:23567314 NCBI chr 5:101,156,643...101,211,738
Ensembl chr 5:101,154,411...101,242,319
JBrowse link
G Por cytochrome p450 oxidoreductase increases expression ISO perfluoro-n-heptanoic acid results in increased expression of POR mRNA CTD PMID:23567314 NCBI chr12:20,951,058...20,999,198
Ensembl chr12:20,951,058...20,999,245
JBrowse link
G Ppara peroxisome proliferator activated receptor alpha increases activity ISO perfluoro-n-heptanoic acid results in increased activity of PPARA protein CTD PMID:22107727 NCBI chr 7:116,832,405...116,900,878
Ensembl chr 7:116,832,756...116,895,346
JBrowse link
G Ptpn11 protein tyrosine phosphatase, non-receptor type 11 multiple interactions ISO perfluoro-n-heptanoic acid binds to and results in decreased activity of PTPN11 protein CTD PMID:27572461 NCBI chr12:35,365,436...35,424,925
Ensembl chr12:35,383,144...35,424,925
JBrowse link
G Scd stearoyl-CoA desaturase increases expression ISO perfluoro-n-heptanoic acid results in increased expression of SCD1 mRNA
perfluoro-n-heptanoic acid results in increased expression of SCD mRNA
CTD PMID:23567314 NCBI chr 1:243,269,745...243,282,878
Ensembl chr 1:243,269,747...243,282,562
JBrowse link
G Slc22a12 solute carrier family 22 member 12 multiple interactions ISO [Chlorine co-treated with perfluoro-n-heptanoic acid] inhibits the reaction [SLC22A12 protein results in increased import of Uric Acid] CTD PMID:20639259 NCBI chr 1:203,845,039...203,852,496
Ensembl chr 1:203,845,048...203,853,555
JBrowse link
G Slc22a6 solute carrier family 22 member 6 multiple interactions
increases import
EXP perfluoro-n-heptanoic acid inhibits the reaction [SLC22A6 protein results in increased import of p-Aminohippuric Acid]
SLC22A6 protein results in increased import of perfluoro-n-heptanoic acid
CTD PMID:19915082 NCBI chr 1:205,522,579...205,531,179
Ensembl chr 1:205,522,729...205,531,173
JBrowse link
G Slc22a8 solute carrier family 22 member 8 multiple interactions EXP perfluoro-n-heptanoic acid inhibits the reaction [SLC22A8 protein results in increased import of estrone sulfate] CTD PMID:19915082 NCBI chr 1:205,496,331...205,516,378
Ensembl chr 1:205,498,084...205,517,450
JBrowse link
G Slc25a34 solute carrier family 25, member 34 increases expression ISO perfluoro-n-heptanoic acid results in increased expression of SLC25A34 mRNA CTD PMID:23567314 NCBI chr 5:153,932,081...153,936,854 JBrowse link
G Ttr transthyretin multiple interactions ISO perfluoro-n-heptanoic acid affects the reaction [Thyroxine binds to TTR protein] CTD PMID:27528273 NCBI chr18:11,941,791...11,951,008
Ensembl chr18:11,943,789...11,951,008
JBrowse link
G Txnip thioredoxin interacting protein increases expression ISO perfluoro-n-heptanoic acid results in increased expression of TXNIP mRNA CTD PMID:23567314 NCBI chr 2:184,093,079...184,096,882
Ensembl chr 2:184,092,991...184,096,886
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 20089
    role 20042
      application 19781
        solvent 16685
          non-polar solvent 8560
            heptane 51
              1-heptanol 2
              1-nitroheptane 0
              2,4-dimethyl-1-heptene 0
              2-isopropyl-5-methyl-1-heptanol 0
              4-heptanone 0
              heptane-1,2,3-triol + 0
              heptyl group 0
              perfluoroheptane + 49
Path 2
Term Annotations click to browse term
  CHEBI ontology 20089
    subatomic particle 20058
      composite particle 20058
        hadron 20088
          baryon 20088
            nucleon 20088
              atomic nucleus 20088
                atom 20058
                  main group element atom 19960
                    main group molecular entity 19960
                      s-block molecular entity 19784
                        hydrogen molecular entity 19777
                          hydrides 19115
                            organic hydride 18675
                              organic fundamental parent 18657
                                hydrocarbon 18408
                                  alkane 14020
                                    heptane 51
                                      1-heptanol 2
                                      1-nitroheptane 0
                                      2,4-dimethyl-1-heptene 0
                                      2-isopropyl-5-methyl-1-heptanol 0
                                      4-heptanone 0
                                      heptane-1,2,3-triol + 0
                                      heptyl group 0
                                      perfluoroheptane + 49
paths to the root