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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:heptane
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Accession:CHEBI:43098 term browser browse the term
Definition:A straight-chain alkane with seven carbon atoms. It has been found in Jeffrey pine (Pinus jeffreyi).
Synonyms:related_synonym: CH3-[CH2]5-CH3;   Formula=C7H16;   Heptan;   InChI=1S/C7H16/c1-3-5-7-6-4-2/h3-7H2,1-2H3;   InChIKey=IMNFDUFMRHMDMM-UHFFFAOYSA-N;   SMILES=CCCCCCC;   n-heptane
 alt_id: CHEBI:32891;   CHEBI:43095
 xref: Beilstein:1730763;   CAS:142-82-5;   Gmelin:49760;   HMDB:HMDB0031447;   MetaCyc:CPD-9286;   PDBeChem:HP6;   PMID:12226360;   PMID:23544797;   Wikipedia:Heptane


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1-heptanol term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cftr CF transmembrane conductance regulator increases activity ISO Heptanol results in increased activity of CFTR protein CTD PMID:14967738 NCBI chr 4:42,693,263...42,860,679
Ensembl chr 4:42,692,836...42,860,676
JBrowse link
G Gja1 gap junction protein, alpha 1 decreases phosphorylation EXP Heptanol results in decreased phosphorylation of GJA1 protein CTD PMID:16563290 NCBI chr20:37,876,650...37,889,097
Ensembl chr20:37,876,650...37,889,089
JBrowse link
perfluoroheptanoic acid term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcb4 ATP binding cassette subfamily B member 4 increases expression ISO perfluoro-n-heptanoic acid results in increased expression of ABCB4 mRNA CTD PMID:23567314 NCBI chr 4:22,133,984...22,192,687
Ensembl chr 4:22,133,521...22,425,515
JBrowse link
G Acsl1 acyl-CoA synthetase long-chain family member 1 increases expression ISO perfluoro-n-heptanoic acid results in increased expression of ACSL1 mRNA CTD PMID:23567314 NCBI chr16:48,937,456...49,003,898
Ensembl chr16:48,937,456...49,003,246
JBrowse link
G Angptl4 angiopoietin-like 4 increases expression ISO perfluoro-n-heptanoic acid results in increased expression of ANGPTL4 mRNA CTD PMID:23567314 NCBI chr 7:18,627,814...18,634,043
Ensembl chr 7:18,627,808...18,634,079
JBrowse link
G Apoa2 apolipoprotein A2 increases expression ISO perfluoro-n-heptanoic acid results in increased expression of APOA2 mRNA CTD PMID:23567314 NCBI chr13:89,596,872...89,598,805
Ensembl chr13:89,597,138...89,598,802
JBrowse link
G Apoa5 apolipoprotein A5 increases expression ISO perfluoro-n-heptanoic acid results in increased expression of APOA5 mRNA CTD PMID:23567314 NCBI chr 8:50,559,079...50,561,720
Ensembl chr 8:50,559,126...50,561,736
JBrowse link
G Ccnd1 cyclin D1 decreases expression ISO perfluoro-n-heptanoic acid results in decreased expression of CCND1 mRNA CTD PMID:23567314 NCBI chr 1:218,090,750...218,100,447
Ensembl chr 1:218,090,750...218,100,325
JBrowse link
G Cpt1a carnitine palmitoyltransferase 1A affects expression ISO perfluoro-n-heptanoic acid affects the expression of CPT1A mRNA CTD PMID:23567314 NCBI chr 1:218,568,157...218,629,679
Ensembl chr 1:218,569,510...218,629,678
JBrowse link
G Cpt1b carnitine palmitoyltransferase 1B affects expression ISO perfluoro-n-heptanoic acid affects the expression of CPT1B mRNA CTD PMID:23567314 NCBI chr 7:130,395,211...130,404,731
Ensembl chr 7:130,395,194...130,405,347
JBrowse link
G Cyp2b1 cytochrome P450, family 2, subfamily b, polypeptide 1 decreases expression ISO perfluoro-n-heptanoic acid results in decreased expression of CYP2B10 mRNA CTD PMID:23567314 NCBI chr 7:99,142,431...99,183,540
Ensembl chr 7:99,142,450...99,181,783
JBrowse link
G Cyp2b3 cytochrome P450, family 2, subfamily b, polypeptide 3 increases expression ISO perfluoro-n-heptanoic acid results in increased expression of CYP2B6 mRNA CTD PMID:23567314 NCBI chr 1:83,163,103...83,236,615
Ensembl chr 1:83,163,079...83,236,615
JBrowse link
G Cyp3a62 cytochrome P450, family 3, subfamily a, polypeptide 62 increases expression ISO perfluoro-n-heptanoic acid results in increased expression of CYP3A4 mRNA CTD PMID:23567314 NCBI chr12:18,679,809...18,709,397
Ensembl chr12:18,678,594...18,709,397
JBrowse link
G Ehhadh enoyl-CoA hydratase and 3-hydroxyacyl CoA dehydrogenase increases expression ISO perfluoro-n-heptanoic acid results in increased expression of EHHADH mRNA CTD PMID:23567314 NCBI chr11:82,945,104...82,978,364
Ensembl chr11:82,945,104...82,978,364
JBrowse link
G Fabp1 fatty acid binding protein 1 increases expression ISO perfluoro-n-heptanoic acid results in increased expression of FABP1 mRNA CTD PMID:23567314 NCBI chr 4:99,063,181...99,066,957
Ensembl chr 4:99,063,181...99,066,954
JBrowse link
G Gadd45b growth arrest and DNA-damage-inducible, beta decreases expression ISO perfluoro-n-heptanoic acid results in decreased expression of GADD45B mRNA CTD PMID:23567314 NCBI chr 7:11,646,283...11,648,338
Ensembl chr 7:11,646,269...11,648,322
JBrowse link
G Hadha hydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit alpha increases expression ISO perfluoro-n-heptanoic acid results in increased expression of HADHA mRNA CTD PMID:23567314 NCBI chr 6:27,589,840...27,628,921
Ensembl chr 6:27,589,657...27,629,175
JBrowse link
G Hmgcs2 3-hydroxy-3-methylglutaryl-CoA synthase 2 increases expression ISO perfluoro-n-heptanoic acid results in increased expression of HMGCS2 mRNA CTD PMID:23567314 NCBI chr 2:200,452,623...200,480,785
Ensembl chr 2:200,452,624...200,479,423
JBrowse link
G Hsd17b4 hydroxysteroid (17-beta) dehydrogenase 4 increases expression ISO perfluoro-n-heptanoic acid results in increased expression of HSD17B4 mRNA CTD PMID:23567314 NCBI chr18:44,810,462...44,897,677
Ensembl chr18:44,810,388...44,897,640
JBrowse link
G Mbl2 mannose binding lectin 2 increases expression ISO perfluoro-n-heptanoic acid results in increased expression of MBL2 mRNA CTD PMID:23567314 NCBI chr 1:248,435,069...248,442,669
Ensembl chr 1:248,723,397...248,729,962
JBrowse link
G Mogat1 monoacylglycerol O-acyltransferase 1 increases expression ISO perfluoro-n-heptanoic acid results in increased expression of MOGAT1 mRNA CTD PMID:23567314 NCBI chr 9:84,405,481...84,418,657
Ensembl chr 9:84,405,477...84,418,591
JBrowse link
G Nr1i2 nuclear receptor subfamily 1, group I, member 2 increases activity ISO perfluoroheptanoic acid results in increased activity of NR1I2 protein CTD PMID:28115241 NCBI chr11:65,022,100...65,058,546
Ensembl chr11:65,022,100...65,058,545
JBrowse link
G Pdk4 pyruvate dehydrogenase kinase 4 increases expression ISO perfluoro-n-heptanoic acid results in increased expression of PDK4 mRNA CTD PMID:23567314 NCBI chr 4:30,546,772...30,556,774
Ensembl chr 4:30,546,664...30,556,814
JBrowse link
G Plin2 perilipin 2 increases expression ISO perfluoro-n-heptanoic acid results in increased expression of PLIN2 mRNA CTD PMID:23567314 NCBI chr 5:104,984,413...105,010,863
Ensembl chr 5:104,984,414...105,010,857
JBrowse link
G Por cytochrome p450 oxidoreductase increases expression ISO perfluoro-n-heptanoic acid results in increased expression of POR mRNA CTD PMID:23567314 NCBI chr12:23,998,411...24,017,063
Ensembl chr12:23,998,411...24,046,814
JBrowse link
G Ppara peroxisome proliferator activated receptor alpha increases activity ISO perfluoro-n-heptanoic acid results in increased activity of PPARA protein CTD PMID:22107727 NCBI chr 7:126,618,872...126,687,282
Ensembl chr 7:126,619,196...126,681,752
JBrowse link
G Ptpn11 protein tyrosine phosphatase, non-receptor type 11 multiple interactions ISO perfluoroheptanoic acid binds to and results in decreased activity of PTPN11 protein CTD PMID:27572461 NCBI chr12:40,895,515...40,955,999
Ensembl chr12:40,895,515...40,955,999
JBrowse link
G Scd stearoyl-CoA desaturase increases expression ISO perfluoro-n-heptanoic acid results in increased expression of SCD1 mRNA
perfluoro-n-heptanoic acid results in increased expression of SCD mRNA
CTD PMID:23567314 NCBI chr 1:264,159,966...264,173,061
Ensembl chr 1:264,160,129...264,172,729
JBrowse link
G Slc22a12 solute carrier family 22 member 12 multiple interactions ISO [Chlorine co-treated with perfluoro-n-heptanoic acid] inhibits the reaction [SLC22A12 protein results in increased import of Uric Acid] CTD PMID:20639259 NCBI chr 1:221,910,787...221,919,277
Ensembl chr 1:221,910,767...221,919,301
JBrowse link
G Slc22a6 solute carrier family 22 member 6 multiple interactions
increases import
EXP perfluoro-n-heptanoic acid inhibits the reaction [SLC22A6 protein results in increased import of p-Aminohippuric Acid]
SLC22A6 protein results in increased import of perfluoro-n-heptanoic acid
CTD PMID:19915082 NCBI chr 1:224,824,809...224,833,284
Ensembl chr 1:224,824,799...224,833,259
JBrowse link
G Slc22a8 solute carrier family 22 member 8 multiple interactions EXP perfluoro-n-heptanoic acid inhibits the reaction [SLC22A8 protein results in increased import of estrone sulfate] CTD PMID:19915082 NCBI chr 1:224,799,444...224,818,482
Ensembl chr 1:224,800,252...224,818,482
JBrowse link
G Slc25a34 solute carrier family 25, member 34 increases expression ISO perfluoro-n-heptanoic acid results in increased expression of SLC25A34 mRNA CTD PMID:23567314 NCBI chr 5:160,175,206...160,179,978
Ensembl chr 5:160,176,124...160,179,978
JBrowse link
G Ttr transthyretin multiple interactions ISO perfluoroheptanoic acid affects the reaction [Thyroxine binds to TTR protein] CTD PMID:27528273 NCBI chr18:15,532,963...15,542,180
Ensembl chr18:15,532,963...15,540,177
JBrowse link
G Txnip thioredoxin interacting protein increases expression ISO perfluoro-n-heptanoic acid results in increased expression of TXNIP mRNA CTD PMID:23567314 NCBI chr 2:198,683,168...198,686,971
Ensembl chr 2:198,683,159...198,686,974
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19883
    role 19833
      application 19505
        solvent 16574
          non-polar solvent 8491
            heptane 34
              1-heptanol 2
              1-nitroheptane 0
              2,4-dimethyl-1-heptene 0
              2-isopropyl-5-methyl-1-heptanol 0
              4-heptanone 0
              heptane-1,2,3-triol + 0
              heptyl group 0
              perfluoroheptane + 32
Path 2
Term Annotations click to browse term
  CHEBI ontology 19883
    subatomic particle 19881
      composite particle 19881
        hadron 19881
          baryon 19881
            nucleon 19881
              atomic nucleus 19881
                atom 19881
                  main group element atom 19771
                    main group molecular entity 19771
                      s-block molecular entity 19520
                        hydrogen molecular entity 19512
                          hydrides 18784
                            organic hydride 18338
                              organic fundamental parent 18338
                                hydrocarbon 18064
                                  alkane 13726
                                    heptane 34
                                      1-heptanol 2
                                      1-nitroheptane 0
                                      2,4-dimethyl-1-heptene 0
                                      2-isopropyl-5-methyl-1-heptanol 0
                                      4-heptanone 0
                                      heptane-1,2,3-triol + 0
                                      heptyl group 0
                                      perfluoroheptane + 32
paths to the root