CHEBI ONTOLOGY - ANNOTATIONS |
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The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
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Term: | guanidine |
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Accession: | CHEBI:42820
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browse the term
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Definition: | An aminocarboxamidine, the parent compound of the guanidines. |
Synonyms: | related_synonym: | Formula=CH5N3; Gu; H2N-C(=NH)-NH2; InChI=1S/CH5N3/c2-1(3)4/h(H5,2,3,4); InChIKey=ZRALSGWEFCBTJO-UHFFFAOYSA-N; SMILES=NC(N)=N; aminomethanamidine; guanidin; iminourea |
| alt_id: | CHEBI:24435; CHEBI:42816 |
| xref: | Beilstein:506044; CAS:113-00-8; DrugBank:DB00536; Drug_Central:1344; Gmelin:100679 |
| xref_mesh: | MESH:D019791 |
| xref: | PDBeChem:GAI; PMID:8070089; Reaxys:506044; Wikipedia:Guanidine |
| cyclic_relationship: | is_conjugate_base_of CHEBI:30087 |
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Alb |
albumin |
multiple interactions affects folding decreases folding |
ISO |
Guanidine affects the folding of [acrylodan binds to ALB protein]; Guanidine inhibits the reaction [prodan binds to ALB protein] Guanidine affects the folding of ALB protein Guanidine results in decreased folding of ALB protein |
CTD |
PMID:12044178 PMID:15353599 |
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NCBI chr14:19,176,275...19,191,793
Ensembl chr14:19,176,277...19,191,863
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Slc22a16 |
solute carrier family 22 member 16 |
multiple interactions |
ISO |
Guanidine inhibits the reaction [SLC22A16 protein results in increased uptake of Tetraethylammonium] |
CTD |
PMID:15963465 |
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NCBI chr20:45,658,398...45,669,192
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Slc22a3 |
solute carrier family 22 member 3 |
increases uptake multiple interactions |
ISO EXP |
SLC22A3 protein results in increased uptake of Guanidine Guanidine inhibits the reaction [SLC22A3 protein results in increased uptake of Tetraethylammonium] Guanidine inhibits the reaction [SLC22A3 protein results in increased uptake of 1-Methyl-4-phenylpyridinium] Guanidine inhibits the reaction [SLC22A3 protein results in increased uptake of 1-Methyl-4-phenylpyridinium analog] |
CTD |
PMID:9830022 PMID:10966924 |
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NCBI chr 1:48,433,079...48,521,261
Ensembl chr 1:48,433,079...48,521,256
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Slc47a1 |
solute carrier family 47 member 1 |
multiple interactions |
ISO |
Guanidine affects the reaction [SLC47A1 protein results in increased uptake of 1-Methyl-4-phenylpyridinium] |
CTD |
PMID:22419765 |
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NCBI chr10:47,631,425...47,685,379
Ensembl chr10:47,632,192...47,666,921
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Slc47a2 |
solute carrier family 47 member 2 |
multiple interactions |
ISO |
Guanidine affects the reaction [SLC47A2 protein results in increased uptake of 1-Methyl-4-phenylpyridinium] |
CTD |
PMID:22419765 |
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NCBI chr10:47,587,909...47,631,373
Ensembl chr10:47,588,497...47,630,799
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Sod1 |
superoxide dismutase 1 |
decreases folding |
ISO |
Guanidine results in decreased folding of SOD1 protein mutant form |
CTD |
PMID:23612299 |
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NCBI chr11:30,363,282...30,368,858
Ensembl chr11:30,363,280...30,368,862
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Anxa10 |
annexin A10 |
increases expression |
ISO |
Thiamethoxam results in increased expression of ANXA10 mRNA |
CTD |
PMID:32194361 |
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NCBI chr16:29,674,699...29,741,521
Ensembl chr16:29,674,793...29,741,465
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Ar |
androgen receptor |
affects binding |
ISO |
Thiamethoxam binds to AR protein |
CTD |
PMID:31550567 |
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NCBI chr X:67,656,253...67,828,998
Ensembl chr X:67,656,253...67,829,026
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Arg1 |
arginase 1 |
decreases expression |
ISO |
Thiamethoxam results in decreased expression of ARG1 mRNA |
CTD |
PMID:32194361 |
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NCBI chr 1:21,525,421...21,537,872
Ensembl chr 1:21,525,421...21,537,863
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Chrnb2 |
cholinergic receptor nicotinic beta 2 subunit |
multiple interactions |
EXP |
Thiamethoxam results in increased activity of [NACHRA1 protein co-treated with CHRNB2 protein] |
CTD |
PMID:16981889 |
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NCBI chr 2:189,088,570...189,096,785
Ensembl chr 2:189,088,570...189,096,785
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Cyp19a1 |
cytochrome P450, family 19, subfamily a, polypeptide 1 |
increases expression increases activity |
ISO |
Thiamethoxam results in increased expression of CYP19A1 mRNA Thiamethoxam results in increased activity of CYP19A1 protein |
CTD |
PMID:26464060 PMID:28750898 |
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NCBI chr 8:58,744,849...58,772,408
Ensembl chr 8:58,744,849...58,772,408
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Cyp2c6v1 |
cytochrome P450, family 2, subfamily C, polypeptide 6, variant 1 |
decreases expression |
ISO |
Thiamethoxam results in decreased expression of CYP2C19 protein |
CTD |
PMID:32194361 |
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NCBI chr 1:147,713,879...147,814,410
Ensembl chr 1:147,713,892...147,888,007
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Cyp3a62 |
cytochrome P450, family 3, subfamily a, polypeptide 62 |
multiple interactions |
ISO |
[NADP co-treated with CYP3A4 protein] results in increased activity of Thiamethoxam |
CTD |
PMID:16153789 |
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NCBI chr12:18,679,809...18,709,397
Ensembl chr12:18,678,594...18,709,397
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Cyp7a1 |
cytochrome P450 family 7 subfamily A member 1 |
decreases expression |
ISO |
Thiamethoxam results in decreased expression of CYP7A1 protein |
CTD |
PMID:32194361 |
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NCBI chr 5:19,358,734...19,368,431
Ensembl chr 5:19,358,734...19,368,431
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Esr1 |
estrogen receptor 1 |
affects binding |
ISO |
Thiamethoxam binds to ESR1 protein |
CTD |
PMID:31550567 |
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NCBI chr 1:41,192,029...41,594,799
Ensembl chr 1:41,192,824...41,594,796
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G6pc1 |
glucose-6-phosphatase catalytic subunit 1 |
decreases expression |
ISO |
Thiamethoxam results in decreased expression of G6PC1 mRNA |
CTD |
PMID:32194361 |
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NCBI chr10:89,286,009...89,296,213
Ensembl chr10:89,285,855...89,296,213
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Gpt |
glutamic--pyruvic transaminase |
decreases activity |
EXP |
Thiamethoxam results in decreased activity of GPT protein |
CTD |
PMID:29197058 |
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NCBI chr 7:117,759,083...117,761,932
Ensembl chr 7:117,759,083...117,761,931
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Nos2 |
nitric oxide synthase 2 |
decreases activity multiple interactions |
ISO |
Thiamethoxam metabolite results in decreased activity of NOS2 protein [Thiamethoxam metabolite results in decreased activity of NOS2 protein] which results in increased chemical synthesis of Formaldehyde |
CTD |
PMID:29197058 |
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NCBI chr10:66,188,290...66,221,621
Ensembl chr10:66,189,786...66,313,190
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Slc22a2 |
solute carrier family 22 member 2 |
decreases activity |
ISO |
Thiamethoxam results in decreased activity of SLC22A2 protein |
CTD |
PMID:31364238 |
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NCBI chr 1:48,318,025...48,360,219
Ensembl chr 1:48,317,995...48,360,261
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Thra |
thyroid hormone receptor alpha |
affects binding |
ISO |
Thiamethoxam binds to THRA protein |
CTD |
PMID:31550567 |
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NCBI chr10:86,657,285...86,684,935
Ensembl chr10:86,657,285...86,684,933
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Tnnt2 |
troponin T2, cardiac type |
increases secretion multiple interactions |
EXP |
Thiamethoxam results in increased secretion of TNNT2 protein fenugreek seed meal inhibits the reaction [Thiamethoxam results in increased secretion of TNNT2 protein]; Polysaccharides inhibits the reaction [Thiamethoxam results in increased secretion of TNNT2 protein] |
CTD |
PMID:30520268 |
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NCBI chr13:52,662,974...52,680,992
Ensembl chr13:52,662,996...52,680,990
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Abca13 |
ATP binding cassette subfamily A member 13 |
increases expression |
ISO |
clothianidin results in increased expression of ABCA13 mRNA |
CTD |
PMID:31626844 |
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NCBI chr14:89,384,512...89,876,748
Ensembl chr14:89,384,512...89,714,917
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Abcb6 |
ATP binding cassette subfamily B member 6 |
decreases expression |
ISO |
clothianidin results in decreased expression of ABCB6 mRNA |
CTD |
PMID:29044138 |
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NCBI chr 9:82,373,950...82,382,228
Ensembl chr 9:82,373,946...82,382,272
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Abcc1 |
ATP binding cassette subfamily C member 1 |
increases expression |
ISO |
clothianidin results in increased expression of ABCC1 mRNA |
CTD |
PMID:31626844 |
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NCBI chr10:549,537...672,235
Ensembl chr10:549,883...672,196
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Abcd2 |
ATP binding cassette subfamily D member 2 |
decreases expression |
ISO |
clothianidin results in decreased expression of ABCD2 mRNA |
CTD |
PMID:31626844 |
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NCBI chr 7:132,294,564...132,343,169
Ensembl chr 7:132,294,562...132,343,169
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Abcd3 |
ATP binding cassette subfamily D member 3 |
decreases expression |
ISO |
clothianidin results in decreased expression of ABCD3 mRNA |
CTD |
PMID:31626844 |
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NCBI chr 2:225,335,708...225,389,120
Ensembl chr 2:225,335,718...225,389,120
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Abcg1 |
ATP binding cassette subfamily G member 1 |
decreases expression |
ISO |
clothianidin results in decreased expression of ABCG1 mRNA |
CTD |
PMID:29044138 |
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NCBI chr20:9,743,269...9,842,735
Ensembl chr20:9,743,269...9,840,489
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Abhd4 |
abhydrolase domain containing 4, N-acyl phospholipase B |
decreases expression |
ISO |
clothianidin results in decreased expression of ABHD4 mRNA |
CTD |
PMID:31626844 |
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NCBI chr15:32,888,233...32,906,861
Ensembl chr15:32,894,938...32,906,850
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Abi3bp |
ABI family member 3 binding protein |
decreases expression |
ISO |
clothianidin results in decreased expression of ABI3BP mRNA |
CTD |
PMID:31626844 |
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NCBI chr11:46,206,932...46,422,791
Ensembl chr11:46,208,075...46,369,577
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Adcy2 |
adenylate cyclase 2 |
increases expression |
ISO |
clothianidin results in increased expression of ADCY2 mRNA |
CTD |
PMID:31626844 |
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NCBI chr 1:37,043,071...37,698,390
Ensembl chr 1:37,507,276...37,698,390
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Adcy4 |
adenylate cyclase 4 |
decreases expression |
ISO |
clothianidin results in decreased expression of ADCY4 mRNA |
CTD |
PMID:29044138 |
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NCBI chr15:34,453,917...34,469,779
Ensembl chr15:34,453,915...34,469,746
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Adgrb2 |
adhesion G protein-coupled receptor B2 |
decreases expression |
ISO |
clothianidin results in decreased expression of ADGRB2 mRNA |
CTD |
PMID:31626844 |
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NCBI chr 5:148,168,530...148,231,587
Ensembl chr 5:148,193,710...148,231,587
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Adgrf5 |
adhesion G protein-coupled receptor F5 |
decreases expression |
ISO |
clothianidin results in decreased expression of ADGRF5 mRNA |
CTD |
PMID:31626844 |
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NCBI chr 9:20,091,121...20,195,706
Ensembl chr 9:20,091,099...20,195,566
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Adgrg6 |
adhesion G protein-coupled receptor G6 |
decreases expression |
ISO |
clothianidin results in decreased expression of ADGRG6 mRNA |
CTD |
PMID:31626844 |
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NCBI chr 1:8,593,342...8,751,540
Ensembl chr 1:8,593,075...8,751,198
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Adrb2 |
adrenoceptor beta 2 |
decreases expression |
ISO |
clothianidin results in decreased expression of ADRB2 mRNA |
CTD |
PMID:31626844 |
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NCBI chr18:57,513,792...57,515,834
Ensembl chr18:57,513,793...57,515,834
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Aff1-as1 |
AFF1 antisense RNA 1 |
decreases expression |
ISO |
clothianidin results in decreased expression of C4ORF36 mRNA |
CTD |
PMID:31626844 |
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NCBI chr14:7,581,189...7,636,823
Ensembl chr14:7,581,189...7,636,822
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Agbl3 |
ATP/GTP binding protein-like 3 |
increases expression |
ISO |
clothianidin results in increased expression of AGBL3 mRNA |
CTD |
PMID:31626844 |
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NCBI chr 4:62,293,158...62,377,740
Ensembl chr 4:62,299,044...62,376,533
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Amz1 |
archaelysin family metallopeptidase 1 |
increases expression |
ISO |
clothianidin results in increased expression of AMZ1 mRNA |
CTD |
PMID:31626844 |
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NCBI chr12:15,975,211...16,011,238
Ensembl chr12:15,976,079...16,002,788
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Ank3 |
ankyrin 3 |
decreases expression |
ISO |
clothianidin results in decreased expression of ANK3 mRNA |
CTD |
PMID:31626844 |
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NCBI chr20:19,948,767...20,480,628
Ensembl chr20:20,105,047...20,480,623
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Ankrd37 |
ankyrin repeat domain 37 |
decreases expression |
ISO |
clothianidin results in decreased expression of ANKRD37 mRNA |
CTD |
PMID:31626844 |
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NCBI chr16:49,463,016...49,465,905
Ensembl chr16:49,462,889...49,465,888
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Aplf |
aprataxin and PNKP like factor |
increases expression |
ISO |
clothianidin results in increased expression of APLF mRNA |
CTD |
PMID:31626844 |
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NCBI chr 4:119,514,822...119,568,764
Ensembl chr 4:119,514,840...119,568,736
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Arhgap17 |
Rho GTPase activating protein 17 |
increases expression |
ISO |
clothianidin results in increased expression of ARHGAP17 mRNA |
CTD |
PMID:31626844 |
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NCBI chr 1:193,239,036...193,328,425
Ensembl chr 1:193,239,040...193,328,371
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Arhgef2 |
Rho/Rac guanine nucleotide exchange factor 2 |
increases expression |
ISO |
clothianidin results in increased expression of ARHGEF2 mRNA |
CTD |
PMID:31626844 |
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NCBI chr 2:187,964,100...188,022,847
Ensembl chr 2:187,977,008...188,021,377
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Arih2os |
ARIH2 opposite strand lncRNA |
increases expression |
ISO |
clothianidin results in increased expression of ARIH2OS mRNA |
CTD |
PMID:31626844 |
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NCBI chr 8:117,443,121...117,447,405
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Arl11 |
ADP-ribosylation factor like GTPase 11 |
increases expression |
ISO |
clothianidin results in increased expression of ARL11 mRNA |
CTD |
PMID:31626844 |
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NCBI chr15:41,639,985...41,645,685
Ensembl chr15:41,643,541...41,645,685
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Arl6 |
ADP-ribosylation factor like GTPase 6 |
increases expression |
ISO |
clothianidin results in increased expression of ARL6 mRNA |
CTD |
PMID:31626844 |
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NCBI chr11:42,858,476...42,884,324
Ensembl chr11:42,858,478...42,884,603
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Asb11 |
ankyrin repeat and SOCS box containing 11 |
increases expression |
ISO |
clothianidin results in increased expression of ASB11 mRNA |
CTD |
PMID:31626844 |
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NCBI chr X:31,758,294...31,781,863
Ensembl chr X:31,700,633...31,780,425
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Asphd1 |
aspartate beta-hydroxylase domain containing 1 |
decreases expression |
ISO |
clothianidin results in decreased expression of ASPHD1 mRNA |
CTD |
PMID:31626844 |
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NCBI chr 1:198,379,060...198,382,982
Ensembl chr 1:198,379,022...198,382,614
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Atp1a2 |
ATPase Na+/K+ transporting subunit alpha 2 |
decreases expression |
ISO |
clothianidin results in decreased expression of ATP1A2 mRNA |
CTD |
PMID:29044138 |
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NCBI chr13:90,651,682...90,676,629
Ensembl chr13:90,651,686...90,676,629
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Atp23 |
ATP23 metallopeptidase and ATP synthase assembly factor homolog |
increases expression |
ISO |
clothianidin results in increased expression of XRCC6BP1 mRNA |
CTD |
PMID:31626844 |
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NCBI chr 7:70,183,625...70,198,655
Ensembl chr 7:70,183,625...70,198,655
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Atp2b3 |
ATPase plasma membrane Ca2+ transporting 3 |
decreases expression |
ISO |
clothianidin results in decreased expression of ATP2B3 mRNA |
CTD |
PMID:29044138 |
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NCBI chr X:157,236,400...157,312,028
Ensembl chr X:157,239,306...157,312,028
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Atp6v0d2 |
ATPase H+ transporting V0 subunit D2 |
increases expression |
ISO |
clothianidin results in increased expression of ATP6V0D2 mRNA |
CTD |
PMID:31626844 |
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NCBI chr 5:33,843,591...33,892,446
Ensembl chr 5:33,843,519...33,892,462
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Awat1 |
acyl-CoA wax alcohol acyltransferase 1 |
increases expression |
ISO |
clothianidin results in increased expression of AWAT1 mRNA |
CTD |
PMID:31626844 |
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NCBI chr X:70,408,124...70,414,369
Ensembl chr X:70,408,064...70,414,368
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Axin1 |
axin 1 |
decreases expression |
ISO |
clothianidin results in decreased expression of AXIN1 mRNA |
CTD |
PMID:31626844 |
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Azin2 |
antizyme inhibitor 2 |
decreases expression |
ISO |
clothianidin results in decreased expression of AZIN2 mRNA |
CTD |
PMID:29044138 |
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NCBI chr 5:147,120,128...147,148,576
Ensembl chr 5:147,120,129...147,148,291
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Barhl1 |
BarH-like homeobox 1 |
increases expression |
ISO |
clothianidin results in increased expression of BARHL1 mRNA |
CTD |
PMID:31626844 |
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NCBI chr 3:7,491,234...7,498,555
Ensembl chr 3:7,491,234...7,498,555
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Bcr |
BCR activator of RhoGEF and GTPase |
decreases expression |
ISO |
clothianidin results in decreased expression of BCR mRNA |
CTD |
PMID:31626844 |
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NCBI chr20:14,421,250...14,546,406
Ensembl chr20:14,421,141...14,545,772
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Bicd2 |
BICD cargo adaptor 2 |
decreases expression |
ISO |
clothianidin results in decreased expression of BICD2 mRNA |
CTD |
PMID:31626844 |
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NCBI chr17:15,673,649...15,718,035
Ensembl chr17:15,673,650...15,718,035
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G |
Bricd5 |
BRICHOS domain containing 5 |
decreases expression |
ISO |
clothianidin results in decreased expression of BRICD5 mRNA |
CTD |
PMID:29044138 |
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NCBI chr10:13,839,599...13,841,132
Ensembl chr10:13,839,956...13,841,018
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C2cd4b |
C2 calcium-dependent domain containing 4B |
increases expression |
ISO |
clothianidin results in increased expression of C2CD4B mRNA |
CTD |
PMID:31626844 |
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NCBI chr 8:73,589,848...73,594,516
Ensembl chr 8:73,593,310...73,594,332
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Ca3 |
carbonic anhydrase 3 |
increases expression |
ISO |
clothianidin results in increased expression of CA3 mRNA |
CTD |
PMID:31626844 |
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NCBI chr 2:88,126,519...88,136,063
Ensembl chr 2:88,126,667...88,135,410
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G |
Cacnb2 |
calcium voltage-gated channel auxiliary subunit beta 2 |
decreases expression |
ISO |
clothianidin results in decreased expression of CACNB2 mRNA |
CTD |
PMID:31626844 |
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NCBI chr17:81,673,862...82,019,219
Ensembl chr17:81,798,756...82,017,682
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Calhm3 |
calcium homeostasis modulator 3 |
increases expression |
ISO |
clothianidin results in increased expression of CALHM3 mRNA |
CTD |
PMID:31626844 |
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NCBI chr 1:266,928,596...266,935,678
Ensembl chr 1:266,929,299...266,934,303
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Capn5 |
calpain 5 |
increases expression |
ISO |
clothianidin results in increased expression of CAPN5 mRNA |
CTD |
PMID:29044138 |
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NCBI chr 1:163,073,134...163,129,736
Ensembl chr 1:163,073,124...163,129,641
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Carmil1 |
capping protein regulator and myosin 1 linker 1 |
decreases expression |
ISO |
clothianidin results in decreased expression of LRRC16A mRNA |
CTD |
PMID:31626844 |
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NCBI chr17:43,050,282...43,339,403
Ensembl chr17:43,050,789...43,339,403
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Carmil3 |
capping protein regulator and myosin 1 linker 3 |
increases expression |
ISO |
clothianidin results in increased expression of CARMIL3 mRNA |
CTD |
PMID:29044138 |
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NCBI chr15:34,167,146...34,184,799
Ensembl chr15:34,167,945...34,184,799
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Ccdc17 |
coiled-coil domain containing 17 |
decreases expression |
ISO |
clothianidin results in decreased expression of CCDC17 mRNA |
CTD |
PMID:29044138 |
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NCBI chr 5:135,440,276...135,445,794
Ensembl chr 5:135,442,031...135,445,791
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Ccdc8 |
coiled-coil domain containing 8 |
increases expression |
ISO |
clothianidin results in increased expression of CCDC8 mRNA |
CTD |
PMID:31626844 |
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NCBI chr 1:78,933,372...78,936,700
Ensembl chr 1:78,933,372...78,936,700
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Ccser1 |
coiled-coil serine-rich protein 1 |
decreases expression |
ISO |
clothianidin results in decreased expression of CCSER1 mRNA |
CTD |
PMID:31626844 |
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NCBI chr 4:91,235,885...92,516,800
Ensembl chr 4:91,373,942...91,972,325
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G |
Cd226 |
CD226 molecule |
decreases expression |
ISO |
clothianidin results in decreased expression of CD226 mRNA |
CTD |
PMID:31626844 |
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NCBI chr18:86,299,392...86,394,772
Ensembl chr18:86,299,463...86,394,765
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G |
Cd34 |
CD34 molecule |
increases expression |
ISO |
clothianidin results in increased expression of CD34 mRNA |
CTD |
PMID:31626844 |
|
NCBI chr13:113,691,842...113,711,259
Ensembl chr13:113,691,932...113,711,647
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G |
Cd74 |
CD74 molecule |
increases expression |
ISO |
clothianidin results in increased expression of CD74 mRNA |
CTD |
PMID:31626844 |
|
NCBI chr18:56,071,420...56,080,851
Ensembl chr18:56,071,478...56,080,849
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G |
Cd8b |
CD8b molecule |
increases expression |
ISO |
clothianidin results in increased expression of CD8B mRNA |
CTD |
PMID:31626844 |
|
NCBI chr 4:99,185,960...99,201,887
Ensembl chr 4:99,185,885...99,202,023
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G |
Cdh8 |
cadherin 8 |
decreases expression |
ISO |
clothianidin results in decreased expression of CDH8 mRNA |
CTD |
PMID:31626844 |
|
NCBI chr19:6,031,654...6,431,502
Ensembl chr19:6,046,665...6,426,216
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G |
Ceacam6 |
CEA cell adhesion molecule 6 |
increases expression |
ISO |
clothianidin results in increased expression of CEACAM6 mRNA |
CTD |
PMID:31626844 |
|
NCBI chr 1:81,683,500...81,701,230
Ensembl chr 1:81,683,463...81,701,317
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G |
Cemip |
cell migration inducing hyaluronidase |
increases expression |
ISO |
clothianidin results in increased expression of CEMIP mRNA |
CTD |
PMID:31626844 |
|
NCBI chr 1:146,069,774...146,226,320
Ensembl chr 1:146,069,771...146,226,462
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G |
Ces2h |
carboxylesterase 2H |
multiple interactions |
ISO |
[clothianidin co-treated with thiacloprid] results in increased expression of CES2 protein |
CTD |
PMID:32201337 |
|
NCBI chr19:37,052,555...37,067,176
Ensembl chr19:37,052,556...37,067,156
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G |
Cfap94 |
cilia and flagella associated protein 94 |
decreases expression |
ISO |
clothianidin results in decreased expression of CFAP94 mRNA |
CTD |
PMID:31626844 |
|
NCBI chr 4:179,440,984...179,476,965
Ensembl chr 4:179,440,953...179,477,070
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G |
Chrna4 |
cholinergic receptor nicotinic alpha 4 subunit |
multiple interactions |
ISO |
clothianidin promotes the reaction [Acetylcholine results in increased activity of [CHRNA4 protein binds to CHRNB2 protein]] |
CTD |
PMID:21538459 |
|
NCBI chr 3:176,533,182...176,547,965
Ensembl chr 3:176,527,516...176,548,208
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G |
Chrnb2 |
cholinergic receptor nicotinic beta 2 subunit |
multiple interactions |
EXP ISO |
clothianidin results in increased activity of [NACHRA1 protein co-treated with CHRNB2 protein]; clothianidin results in increased activity of [NACHRA8 protein co-treated with CHRNB2 protein] clothianidin promotes the reaction [Acetylcholine results in increased activity of [CHRNA4 protein binds to CHRNB2 protein]] |
CTD |
PMID:16981889 PMID:21538459 PMID:25459289 |
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NCBI chr 2:189,088,570...189,096,785
Ensembl chr 2:189,088,570...189,096,785
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G |
Chst3 |
carbohydrate sulfotransferase 3 |
increases expression |
ISO |
clothianidin results in increased expression of CHST3 mRNA |
CTD |
PMID:29044138 |
|
NCBI chr20:29,731,828...29,768,656
Ensembl chr20:29,731,816...29,738,506
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G |
Clec3b |
C-type lectin domain family 3, member B |
increases expression |
ISO |
clothianidin results in increased expression of CLEC3B mRNA |
CTD |
PMID:31626844 |
|
NCBI chr 8:132,241,016...132,248,066
Ensembl chr 8:132,241,134...132,246,694
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G |
Cmtm5 |
CKLF-like MARVEL transmembrane domain containing 5 |
increases expression |
ISO |
clothianidin results in increased expression of CMTM5 mRNA |
CTD |
PMID:31626844 |
|
NCBI chr15:33,600,016...33,602,839
Ensembl chr15:33,600,102...33,602,834
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G |
Cntnap1 |
contactin associated protein 1 |
decreases expression |
ISO |
clothianidin results in decreased expression of CNTNAP1 mRNA |
CTD |
PMID:31626844 |
|
NCBI chr10:89,087,904...89,103,615
Ensembl chr10:89,089,646...89,103,614
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G |
Col12a1 |
collagen type XII alpha 1 chain |
decreases expression |
ISO |
clothianidin results in decreased expression of COL12A1 mRNA |
CTD |
PMID:31626844 |
|
NCBI chr 8:87,042,820...87,150,701
Ensembl chr 8:87,040,799...87,158,368
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G |
Col1a1 |
collagen type I alpha 1 chain |
decreases expression |
ISO |
clothianidin results in decreased expression of COL1A1 mRNA |
CTD |
PMID:29044138 |
|
NCBI chr10:82,745,801...82,762,790
Ensembl chr10:82,745,801...82,762,789
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G |
Col6a2 |
collagen type VI alpha 2 chain |
increases expression |
ISO |
clothianidin results in increased expression of COL6A2 mRNA |
CTD |
PMID:31626844 |
|
NCBI chr20:12,773,472...12,801,179
Ensembl chr20:12,773,427...12,801,180
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G |
Col7a1 |
collagen type VII alpha 1 chain |
decreases expression |
ISO |
clothianidin results in decreased expression of COL7A1 mRNA |
CTD |
PMID:29044138 |
|
NCBI chr 8:117,694,441...117,726,844
Ensembl chr 8:117,694,605...117,726,844
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G |
Coro2b |
coronin 2B |
decreases expression |
ISO |
clothianidin results in decreased expression of CORO2B mRNA |
CTD |
PMID:31626844 |
|
NCBI chr 8:67,374,617...67,492,490
Ensembl chr 8:67,376,294...67,492,037
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G |
Cpeb3 |
cytoplasmic polyadenylation element binding protein 3 |
decreases expression |
ISO |
clothianidin results in decreased expression of CPEB3 mRNA |
CTD |
PMID:31626844 |
|
NCBI chr 1:255,660,165...255,842,671
Ensembl chr 1:255,665,238...255,815,733
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G |
Cpne4 |
copine 4 |
increases expression |
ISO |
clothianidin results in increased expression of CPNE4 mRNA |
CTD |
PMID:31626844 |
|
NCBI chr 8:113,105,814...113,586,429
Ensembl chr 8:113,105,814...113,586,418
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G |
Csmd1 |
CUB and Sushi multiple domains 1 |
increases expression |
ISO |
clothianidin results in increased expression of CSMD1 mRNA |
CTD |
PMID:31626844 |
|
NCBI chr16:77,152,823...78,850,222
Ensembl chr16:78,539,489...78,850,222
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G |
Cxadr |
CXADR, Ig-like cell adhesion molecule |
increases expression |
ISO |
clothianidin results in increased expression of CXADR mRNA |
CTD |
PMID:29044138 |
|
NCBI chr11:16,826,269...16,873,564
Ensembl chr11:16,826,399...16,873,562
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G |
Cyp1a2 |
cytochrome P450, family 1, subfamily a, polypeptide 2 |
multiple interactions increases expression |
ISO |
[clothianidin co-treated with enilconazole] results in increased expression of CYP1A2 mRNA; [enilconazole co-treated with thiacloprid co-treated with clothianidin] results in increased expression of CYP1A2 mRNA clothianidin results in increased expression of CYP1A2 mRNA |
CTD |
PMID:32201337 |
|
NCBI chr 8:62,451,360...62,458,244
Ensembl chr 8:62,451,329...62,458,301
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G |
Cyp1b1 |
cytochrome P450, family 1, subfamily b, polypeptide 1 |
multiple interactions |
ISO |
[clothianidin co-treated with enilconazole] results in increased expression of CYP1B1 protein |
CTD |
PMID:32201337 |
|
NCBI chr 6:2,308,179...2,316,739
Ensembl chr 6:2,307,808...2,316,722
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G |
Cyp2b3 |
cytochrome P450, family 2, subfamily b, polypeptide 3 |
multiple interactions |
ISO |
[clothianidin co-treated with thiacloprid] results in increased expression of CYP2B6 protein |
CTD |
PMID:32201337 |
|
NCBI chr 1:83,163,103...83,236,615
Ensembl chr 1:83,163,079...83,236,615
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G |
Cyp2c11 |
cytochrome P450, subfamily 2, polypeptide 11 |
multiple interactions |
ISO |
[clothianidin co-treated with thiacloprid] results in increased expression of CYP2C9 protein |
CTD |
PMID:32201337 |
|
NCBI chr 1:257,676,172...258,004,428
Ensembl chr 1:257,970,345...258,004,434
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G |
Cyp2e1 |
cytochrome P450, family 2, subfamily e, polypeptide 1 |
decreases expression multiple interactions |
ISO |
clothianidin results in decreased expression of CYP2E1 mRNA [clothianidin co-treated with enilconazole] results in decreased expression of CYP2E1 mRNA; [clothianidin co-treated with thiacloprid] results in increased expression of CYP2E1 protein; [enilconazole co-treated with thiacloprid co-treated with clothianidin] results in decreased expression of CYP2E1 mRNA; [thiacloprid co-treated with clothianidin] results in decreased expression of CYP2E1 mRNA |
CTD |
PMID:32201337 |
|
NCBI chr 1:213,511,892...213,522,195
Ensembl chr 1:213,511,874...213,535,542
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G |
Cyp3a62 |
cytochrome P450, family 3, subfamily a, polypeptide 62 |
multiple interactions increases expression |
ISO |
[clothianidin co-treated with enilconazole] results in increased expression of CYP3A4 mRNA; [clothianidin co-treated with enilconazole] results in increased expression of CYP3A4 protein; [clothianidin co-treated with thiacloprid] results in increased expression of CYP3A4 protein; [enilconazole co-treated with thiacloprid co-treated with clothianidin] results in increased expression of CYP3A4 mRNA clothianidin results in increased expression of CYP3A4 mRNA |
CTD |
PMID:32201337 |
|
NCBI chr12:18,679,809...18,709,397
Ensembl chr12:18,678,594...18,709,397
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G |
Cyp3a9 |
cytochrome P450, family 3, subfamily a, polypeptide 9 |
multiple interactions increases expression |
ISO |
[clothianidin co-treated with enilconazole] results in increased expression of CYP3A5 protein; [thiacloprid co-treated with clothianidin] results in increased expression of CYP3A5 mRNA clothianidin results in increased expression of CYP3A5 mRNA |
CTD |
PMID:32201337 |
|
NCBI chr12:19,074,288...19,114,491
Ensembl chr12:19,074,583...19,114,399
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G |
Cyth4 |
cytohesin 4 |
increases expression |
ISO |
clothianidin results in increased expression of CYTH4 mRNA |
CTD |
PMID:31626844 |
|
NCBI chr 7:119,820,521...119,845,003
Ensembl chr 7:119,820,537...119,845,003
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G |
Dact1 |
dishevelled-binding antagonist of beta-catenin 1 |
decreases expression |
ISO |
clothianidin results in decreased expression of DACT1 mRNA |
CTD |
PMID:31626844 |
|
NCBI chr 6:93,740,440...93,751,003
Ensembl chr 6:93,740,586...93,749,809
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G |
Defa5 |
defensin alpha 5 |
decreases expression |
ISO |
clothianidin results in decreased expression of DEFA5 mRNA |
CTD |
PMID:31626844 |
|
NCBI chr16:75,338,050...75,340,401
Ensembl chr16:75,338,052...75,340,360
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G |
Des |
desmin |
increases expression |
ISO |
clothianidin results in increased expression of DES mRNA |
CTD |
PMID:31626844 |
|
NCBI chr 9:82,556,574...82,564,288
Ensembl chr 9:82,556,573...82,564,294
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G |
Dgkd |
diacylglycerol kinase, delta |
increases expression |
ISO |
clothianidin results in increased expression of DGKD mRNA |
CTD |
PMID:31626844 |
|
NCBI chr 9:94,980,328...95,071,531
Ensembl chr 9:94,980,409...95,069,714
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G |
Dio3 |
iodothyronine deiodinase 3 |
increases expression |
ISO |
clothianidin results in increased expression of DIO3 mRNA |
CTD |
PMID:31626844 |
|
NCBI chr 6:134,627,278...134,629,139
Ensembl chr 6:134,627,278...134,629,138
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G |
Dll3 |
delta like canonical Notch ligand 3 |
decreases expression |
ISO |
clothianidin results in decreased expression of DLL3 mRNA |
CTD |
PMID:31626844 |
|
NCBI chr 1:85,485,875...85,493,683
Ensembl chr 1:85,485,289...85,493,685
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|
G |
Dnajc21 |
DnaJ heat shock protein family (Hsp40) member C21 |
increases expression |
ISO |
clothianidin results in increased expression of DNAJC21 mRNA |
CTD |
PMID:31626844 |
|
NCBI chr 2:60,419,446...60,446,656
Ensembl chr 2:60,419,525...60,446,510
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G |
Dnajc28 |
DnaJ heat shock protein family (Hsp40) member C28 |
decreases expression |
ISO |
clothianidin results in decreased expression of DNAJC28 mRNA |
CTD |
PMID:31626844 |
|
NCBI chr11:31,770,164...31,772,984
Ensembl chr11:31,770,165...31,772,984
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G |
Dnajc5g |
DnaJ heat shock protein family (Hsp40) member C5 gamma |
increases expression |
ISO |
clothianidin results in increased expression of DNAJC5G mRNA |
CTD |
PMID:31626844 |
|
NCBI chr 6:26,625,526...26,629,651
Ensembl chr 6:26,625,525...26,629,654
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G |
Dnase1l2 |
deoxyribonuclease 1 like 2 |
decreases expression |
ISO |
clothianidin results in decreased expression of DNASE1L2 mRNA |
CTD |
PMID:29044138 |
|
NCBI chr10:13,812,335...13,814,514
Ensembl chr10:13,812,707...13,814,304
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G |
Dnhd1 |
dynein heavy chain domain 1 |
decreases expression |
ISO |
clothianidin results in decreased expression of DNHD1 mRNA |
CTD |
PMID:29044138 |
|
NCBI chr 1:170,473,792...170,570,220
Ensembl chr 1:170,471,272...170,565,063
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G |
Dok5 |
docking protein 5 |
decreases expression |
ISO |
clothianidin results in decreased expression of DOK5 mRNA |
CTD |
PMID:31626844 |
|
NCBI chr 3:168,345,116...168,482,445
Ensembl chr 3:168,345,152...168,482,441
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G |
Dus3l |
dihydrouridine synthase 3-like |
increases expression |
ISO |
clothianidin results in increased expression of DUS3L mRNA |
CTD |
PMID:31626844 |
|
NCBI chr 9:10,289,440...10,294,213
Ensembl chr 9:10,289,446...10,293,980
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G |
Dusp15 |
dual specificity phosphatase 15 |
increases expression |
ISO |
clothianidin results in increased expression of DUSP15 mRNA |
CTD |
PMID:29044138 |
|
NCBI chr 3:148,417,990...148,428,494
Ensembl chr 3:148,417,993...148,428,494
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G |
Dusp16 |
dual specificity phosphatase 16 |
decreases expression |
ISO |
clothianidin results in decreased expression of DUSP16 mRNA |
CTD |
PMID:31626844 |
|
NCBI chr 4:168,470,141...168,551,346
Ensembl chr 4:168,472,412...168,517,177
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G |
Eaf2 |
ELL associated factor 2 |
decreases expression |
ISO |
clothianidin results in decreased expression of EAF2 mRNA |
CTD |
PMID:31626844 |
|
NCBI chr11:66,878,658...66,923,092
Ensembl chr11:66,878,658...66,923,092
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G |
Ece2 |
endothelin-converting enzyme 2 |
increases expression |
ISO |
clothianidin results in increased expression of ECE2 mRNA |
CTD |
PMID:31626844 |
|
NCBI chr11:83,948,896...83,985,429
Ensembl chr11:83,948,230...83,964,055
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G |
Efcab12 |
EF-hand calcium binding domain 12 |
decreases expression |
ISO |
clothianidin results in decreased expression of EFCAB12 mRNA |
CTD |
PMID:29044138 |
|
NCBI chr 4:147,720,813...147,743,342
Ensembl chr 4:147,721,045...147,742,114
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G |
Efs |
embryonal Fyn-associated substrate |
decreases expression |
ISO |
clothianidin results in decreased expression of EFS mRNA |
CTD |
PMID:31626844 |
|
NCBI chr15:33,579,952...33,590,217
Ensembl chr15:33,578,381...33,589,522
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G |
Eif3f |
eukaryotic translation initiation factor 3, subunit F |
decreases expression |
ISO |
clothianidin results in decreased expression of EIF3F mRNA |
CTD |
PMID:31626844 |
|
NCBI chr 1:173,532,826...173,541,806
Ensembl chr 1:173,532,803...173,541,847
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G |
Elf1 |
E74 like ETS transcription factor 1 |
increases expression |
ISO |
clothianidin results in increased expression of ELF1 mRNA |
CTD |
PMID:31626844 |
|
NCBI chr15:61,772,544...61,868,442
Ensembl chr15:61,826,711...61,868,343
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G |
Elmod1 |
ELMO domain containing 1 |
decreases expression |
ISO |
clothianidin results in decreased expression of ELMOD1 mRNA |
CTD |
PMID:31626844 |
|
NCBI chr 8:58,486,078...58,542,884
Ensembl chr 8:58,486,078...58,542,844
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|
G |
Enpp4 |
ectonucleotide pyrophosphatase/phosphodiesterase 4 |
increases expression |
ISO |
clothianidin results in increased expression of ENPP4 mRNA |
CTD |
PMID:29044138 |
|
NCBI chr 9:19,446,807...19,457,946
Ensembl chr 9:19,448,269...19,457,946
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G |
Epdr1 |
ependymin related 1 |
increases expression |
ISO |
clothianidin results in increased expression of EPDR1 mRNA |
CTD |
PMID:29044138 |
|
NCBI chr17:47,397,558...47,422,183
Ensembl chr17:47,397,558...47,422,182
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|
G |
Epn3 |
epsin 3 |
decreases expression |
ISO |
clothianidin results in decreased expression of EPN3 mRNA |
CTD |
PMID:31626844 |
|
NCBI chr10:82,220,762...82,231,200
Ensembl chr10:82,220,762...82,229,140
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G |
Eps8 |
epidermal growth factor receptor pathway substrate 8 |
increases expression |
ISO |
clothianidin results in increased expression of EPS8 mRNA |
CTD |
PMID:29044138 |
|
NCBI chr 4:171,475,155...171,645,620
Ensembl chr 4:171,475,567...171,591,882
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G |
Erbb3 |
erb-b2 receptor tyrosine kinase 3 |
increases expression |
ISO |
clothianidin results in increased expression of ERBB3 mRNA |
CTD |
PMID:31626844 |
|
NCBI chr 7:2,989,202...3,010,610
Ensembl chr 7:2,989,340...3,010,350
|
|
G |
Ergic1 |
endoplasmic reticulum-golgi intermediate compartment 1 |
increases expression |
ISO |
clothianidin results in increased expression of ERGIC1 mRNA |
CTD |
PMID:31626844 |
|
NCBI chr10:16,821,393...16,912,050
Ensembl chr10:16,821,880...16,910,641
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G |
Exoc4 |
exocyst complex component 4 |
decreases expression |
ISO |
clothianidin results in decreased expression of EXOC4 mRNA |
CTD |
PMID:31626844 |
|
NCBI chr 4:60,549,128...61,358,305
Ensembl chr 4:60,549,197...61,355,994
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|
G |
Ezh2 |
enhancer of zeste 2 polycomb repressive complex 2 subunit |
decreases expression |
ISO |
clothianidin results in decreased expression of EZH2 mRNA |
CTD |
PMID:31626844 |
|
NCBI chr 4:77,284,404...77,347,011
Ensembl chr 4:77,284,404...77,347,011
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|
G |
F2 |
coagulation factor II |
decreases expression |
ISO |
clothianidin results in decreased expression of F2 mRNA |
CTD |
PMID:31626844 |
|
NCBI chr 3:80,529,468...80,542,993
Ensembl chr 3:80,529,428...80,543,031
|
|
G |
Fam110c |
family with sequence similarity 110, member C |
increases expression |
ISO |
clothianidin results in increased expression of FAM110C mRNA |
CTD |
PMID:31626844 |
|
NCBI chr 6:49,968,473...49,974,730
Ensembl chr 6:49,968,473...49,974,728
|
|
G |
Fam131a |
family with sequence similarity 131, member A |
decreases expression |
ISO |
clothianidin results in decreased expression of FAM131A mRNA |
CTD |
PMID:31626844 |
|
NCBI chr11:83,897,330...83,907,292
Ensembl chr11:83,896,873...83,905,889
|
|
G |
Fam151b |
family with sequence similarity 151, member B |
decreases expression |
ISO |
clothianidin results in decreased expression of FAM151B mRNA |
CTD |
PMID:31626844 |
|
NCBI chr 2:22,023,038...22,059,166
Ensembl chr 2:22,023,052...22,059,149
|
|
G |
Fam169a |
family with sequence similarity 169, member A |
increases expression |
ISO |
clothianidin results in increased expression of FAM169A mRNA |
CTD |
PMID:29044138 |
|
NCBI chr 2:27,884,748...27,941,069
Ensembl chr 2:27,905,535...27,938,525
|
|
G |
Fam229a |
family with sequence similarity 229, member A |
decreases expression |
ISO |
clothianidin results in decreased expression of FAM229A mRNA |
CTD |
PMID:29044138 |
|
NCBI chr 5:147,692,391...147,693,380
Ensembl chr 5:147,692,391...147,693,380
|
|
G |
Fam243a |
family with sequence similarity 243 member A |
increases expression |
ISO |
clothianidin results in increased expression of C21ORF140 mRNA |
CTD |
PMID:31626844 |
|
NCBI chr11:32,466,998...32,469,566
Ensembl chr11:32,467,001...32,469,566
|
|
G |
Fbxo33 |
F-box protein 33 |
decreases expression |
ISO |
clothianidin results in decreased expression of FBXO33 mRNA |
CTD |
PMID:31626844 |
|
NCBI chr 6:80,302,291...80,334,536
Ensembl chr 6:80,302,303...80,334,522
|
|
G |
Fcna |
ficolin A |
increases expression |
ISO |
clothianidin results in increased expression of FCN3 mRNA |
CTD |
PMID:31626844 |
|
NCBI chr 3:2,850,006...2,853,230
Ensembl chr 3:2,849,984...2,853,272
|
|
G |
Fer1l4 |
fer-1-like family member 4 |
decreases expression |
ISO |
clothianidin results in decreased expression of FER1L4 mRNA |
CTD |
PMID:29044138 |
|
NCBI chr 3:151,564,604...151,600,140
Ensembl chr 3:151,564,604...151,600,140
|
|
G |
Filip1 |
filamin A interacting protein 1 |
increases expression |
ISO |
clothianidin results in increased expression of FILIP1 mRNA |
CTD |
PMID:31626844 |
|
NCBI chr 8:87,257,312...87,453,432
Ensembl chr 8:87,256,264...87,419,564
|
|
G |
Fitm1 |
fat storage-inducing transmembrane protein 1 |
increases expression |
ISO |
clothianidin results in increased expression of FITM1 mRNA |
CTD |
PMID:31626844 |
|
NCBI chr15:34,251,805...34,253,074
Ensembl chr15:34,251,606...34,253,073
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|
G |
Folr2 |
folate receptor beta |
increases expression |
ISO |
clothianidin results in increased expression of FOLR2 mRNA |
CTD |
PMID:31626844 |
|
NCBI chr 1:166,915,045...166,933,377
Ensembl chr 1:166,915,045...166,919,302
|
|
G |
Foxo1 |
forkhead box O1 |
increases expression |
ISO |
clothianidin results in increased expression of FOXO1 mRNA |
CTD |
PMID:31626844 |
|
NCBI chr 2:141,451,234...141,527,016
Ensembl chr 2:141,451,234...141,527,016
|
|
G |
Foxo4 |
forkhead box O4 |
decreases expression |
ISO |
clothianidin results in decreased expression of FOXO4 mRNA |
CTD |
PMID:29044138 |
|
NCBI chr X:71,155,284...71,162,158
Ensembl chr X:71,155,601...71,162,158
|
|
G |
Fyb1 |
FYN binding protein 1 |
decreases expression |
ISO |
clothianidin results in decreased expression of FYB mRNA |
CTD |
PMID:31626844 |
|
NCBI chr 2:55,834,904...55,983,805
Ensembl chr 2:55,835,151...55,983,804
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|
G |
Gask1a |
golgi associated kinase 1A |
increases expression |
ISO |
clothianidin results in increased expression of FAM198A mRNA |
CTD |
PMID:31626844 |
|
NCBI chr 8:130,581,072...130,614,118
Ensembl chr 8:130,581,062...130,612,510
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|
G |
Ghrhr |
growth hormone releasing hormone receptor |
increases expression |
ISO |
clothianidin results in increased expression of GHRHR mRNA |
CTD |
PMID:31626844 |
|
NCBI chr 4:85,587,321...85,602,389
Ensembl chr 4:85,588,595...85,601,666
|
|
G |
Gli1 |
GLI family zinc finger 1 |
decreases expression |
ISO |
clothianidin results in decreased expression of GLI1 mRNA |
CTD |
PMID:31626844 |
|
NCBI chr 7:70,620,794...70,633,171
Ensembl chr 7:70,620,766...70,630,338
|
|
G |
Gngt1 |
G protein subunit gamma transducin 1 |
decreases expression |
ISO |
clothianidin results in decreased expression of GNGT1 mRNA |
CTD |
PMID:31626844 |
|
NCBI chr 4:28,972,339...28,975,419
Ensembl chr 4:28,972,434...28,975,419
|
|
G |
Gpc6 |
glypican 6 |
increases expression |
ISO |
clothianidin results in increased expression of GPC6 mRNA |
CTD |
PMID:31626844 |
|
NCBI chr15:102,164,091...103,174,721
Ensembl chr15:102,164,751...103,170,847
|
|
G |
Gpcpd1 |
glycerophosphocholine phosphodiesterase 1 |
increases expression |
ISO |
clothianidin results in increased expression of GPCPD1 mRNA |
CTD |
PMID:31626844 |
|
NCBI chr 3:125,169,131...125,213,598
Ensembl chr 3:125,169,135...125,213,607
|
|
G |
Gpihbp1 |
glycosylphosphatidylinositol anchored high density lipoprotein binding protein 1 |
increases expression |
ISO |
clothianidin results in increased expression of GPIHBP1 mRNA |
CTD |
PMID:31626844 |
|
NCBI chr 7:116,632,496...116,635,543
Ensembl chr 7:116,632,506...116,634,293
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|
G |
Gpx4 |
glutathione peroxidase 4 |
decreases expression |
ISO |
clothianidin results in decreased expression of GPX4 protein |
CTD |
PMID:25960033 |
|
NCBI chr 7:12,516,357...12,519,154
Ensembl chr 7:12,516,352...12,519,154
|
|
G |
Gramd1c |
GRAM domain containing 1C |
decreases expression |
ISO |
clothianidin results in decreased expression of GRAMD1C mRNA |
CTD |
PMID:31626844 |
|
NCBI chr11:61,609,370...61,659,355 NCBI chr11:62,580,983...62,634,961
Ensembl chr11:61,605,937...62,634,803
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|
G |
Gramd2a |
GRAM domain containing 2A |
decreases expression |
ISO |
clothianidin results in decreased expression of GRAMD2 mRNA |
CTD |
PMID:31626844 |
|
NCBI chr 8:64,503,058...64,539,149
Ensembl chr 8:64,531,594...64,539,367
|
|
G |
Gskip |
GSK3B interacting protein |
increases expression |
ISO |
clothianidin results in increased expression of GSKIP mRNA |
CTD |
PMID:29044138 |
|
NCBI chr 6:129,512,950...129,536,320
Ensembl chr 6:129,519,709...129,536,221
|
|
G |
Gtf3c5 |
general transcription factor IIIC subunit 5 |
increases expression |
ISO |
clothianidin results in increased expression of GTF3C5 mRNA |
CTD |
PMID:31626844 |
|
NCBI chr 3:7,144,354...7,164,678
Ensembl chr 3:7,144,250...7,164,654
|
|
G |
Gtsf1l |
gametocyte specific factor 1-like |
increases expression |
ISO |
clothianidin results in increased expression of GTSF1L mRNA |
CTD |
PMID:31626844 |
|
NCBI chr 3:159,452,355...159,453,243
|
|
G |
Gypc |
glycophorin C (Gerbich blood group) |
increases expression |
ISO |
clothianidin results in increased expression of GYPC mRNA |
CTD |
PMID:31626844 |
|
NCBI chr18:25,312,386...25,344,614
Ensembl chr18:25,312,387...25,344,614
|
|
G |
H1f7 |
H1.7 linker histone |
increases expression |
ISO |
clothianidin results in increased expression of H1-7 mRNA |
CTD |
PMID:31626844 |
|
NCBI chr 7:139,871,491...139,872,858
Ensembl chr 7:139,871,479...139,872,900
|
|
G |
Hacd2 |
3-hydroxyacyl-CoA dehydratase 2 |
increases expression |
ISO |
clothianidin results in increased expression of HACD2 mRNA |
CTD |
PMID:29044138 |
|
NCBI chr11:68,893,684...68,985,635
Ensembl chr11:68,894,445...68,989,988
|
|
G |
Hck |
HCK proto-oncogene, Src family tyrosine kinase |
increases expression |
ISO |
clothianidin results in increased expression of HCK mRNA |
CTD |
PMID:31626844 |
|
NCBI chr 3:148,579,917...148,623,026
Ensembl chr 3:148,579,920...148,623,033
|
|
G |
Hectd2 |
HECT domain E3 ubiquitin protein ligase 2 |
increases expression |
ISO |
clothianidin results in increased expression of HECTD2 mRNA |
CTD |
PMID:29044138 |
|
NCBI chr 1:255,186,729...255,254,307
Ensembl chr 1:255,185,629...255,254,307
|
|
G |
Hecw2 |
HECT, C2 and WW domain containing E3 ubiquitin protein ligase 2 |
decreases expression |
ISO |
clothianidin results in decreased expression of HECW2 mRNA |
CTD |
PMID:31626844 |
|
NCBI chr 9:60,451,476...60,843,160
Ensembl chr 9:60,457,215...60,672,246
|
|
G |
Hgf |
hepatocyte growth factor |
decreases expression |
ISO |
clothianidin results in decreased expression of HGF mRNA |
CTD |
PMID:31626844 |
|
NCBI chr 4:15,435,460...15,505,377
Ensembl chr 4:15,433,295...15,505,362
|
|
G |
Hid1 |
HID1 domain containing |
decreases expression |
ISO |
clothianidin results in decreased expression of HID1 mRNA |
CTD |
PMID:31626844 |
|
NCBI chr10:103,899,160...103,919,649
Ensembl chr10:103,899,150...103,919,605
|
|
G |
Hmbs |
hydroxymethylbilane synthase |
increases expression |
ISO |
clothianidin results in increased expression of HMBS mRNA |
CTD |
PMID:31626844 |
|
NCBI chr 8:48,667,278...48,674,673
Ensembl chr 8:48,667,275...48,674,748
|
|
G |
Hnf1b |
HNF1 homeobox B |
increases expression |
ISO |
clothianidin results in increased expression of HNF1B mRNA |
CTD |
PMID:31626844 |
|
NCBI chr10:71,159,863...71,218,902
Ensembl chr10:71,159,869...71,218,902
|
|
G |
Hnf4a |
hepatocyte nuclear factor 4, alpha |
increases expression |
ISO |
clothianidin results in increased expression of HNF4A mRNA |
CTD |
PMID:31626844 |
|
NCBI chr 3:159,902,441...159,965,003
Ensembl chr 3:159,902,441...159,965,003
|
|
G |
Hnrnpk |
heterogeneous nuclear ribonucleoprotein K |
decreases expression |
ISO |
clothianidin results in decreased expression of HNRNPK mRNA |
CTD |
PMID:31626844 |
|
NCBI chr17:6,664,730...6,676,753
Ensembl chr17:6,665,659...6,676,654
|
|
G |
Il17re |
interleukin 17 receptor E |
decreases expression |
ISO |
clothianidin results in decreased expression of IL17RE mRNA |
CTD |
PMID:29044138 |
|
NCBI chr 4:145,413,157...145,426,608
Ensembl chr 4:145,413,230...145,426,603
|
|
G |
Il18bp |
interleukin 18 binding protein |
decreases expression |
ISO |
clothianidin results in decreased expression of IL18BP mRNA |
CTD |
PMID:29044138 |
|
NCBI chr 1:167,091,521...167,095,727
Ensembl chr 1:167,091,522...167,093,560
|
|
G |
Il2rg |
interleukin 2 receptor subunit gamma |
increases expression |
ISO |
clothianidin results in increased expression of IL2RG mRNA |
CTD |
PMID:31626844 |
|
NCBI chr X:71,165,378...71,169,078
Ensembl chr X:71,162,585...71,169,865
|
|
G |
Immp1l |
inner mitochondrial membrane peptidase subunit 1 |
increases expression |
ISO |
clothianidin results in increased expression of IMMP1L mRNA |
CTD |
PMID:31626844 |
|
NCBI chr 3:95,955,126...96,024,316
Ensembl chr 3:95,959,703...96,024,836
|
|
G |
Insyn2b |
inhibitory synaptic factor family member 2B |
decreases expression |
ISO |
clothianidin results in decreased expression of FAM196B mRNA |
CTD |
PMID:31626844 |
|
NCBI chr10:19,270,956...19,392,214
|
|
G |
Irx5 |
iroquois homeobox 5 |
decreases expression |
ISO |
clothianidin results in decreased expression of IRX5 mRNA |
CTD |
PMID:31626844 |
|
NCBI chr19:16,415,813...16,421,088
Ensembl chr19:16,415,636...16,421,191
|
|
G |
Itsn1 |
intersectin 1 |
decreases expression |
ISO |
clothianidin results in decreased expression of ITSN1 mRNA |
CTD |
PMID:31626844 |
|
NCBI chr11:31,943,119...32,069,249
Ensembl chr11:31,893,489...32,069,249
|
|
G |
Jak2 |
Janus kinase 2 |
decreases expression |
ISO |
clothianidin results in decreased expression of JAK2 mRNA |
CTD |
PMID:31626844 |
|
NCBI chr 1:247,398,667...247,457,521
Ensembl chr 1:247,398,598...247,458,509
|
|
G |
Kat6b |
lysine acetyltransferase 6B |
decreases expression |
ISO |
clothianidin results in decreased expression of KAT6B mRNA |
CTD |
PMID:31626844 |
|
NCBI chr15:2,811,933...2,966,833
Ensembl chr15:2,813,537...2,966,576
|
|
G |
Kcnc4 |
potassium voltage-gated channel subfamily C member 4 |
increases expression |
ISO |
clothianidin results in increased expression of KCNC4 mRNA |
CTD |
PMID:31626844 |
|
NCBI chr 2:210,220,908...210,241,447
Ensembl chr 2:210,220,908...210,241,455
|
|
G |
Kcnd3 |
potassium voltage-gated channel subfamily D member 3 |
decreases expression |
ISO |
clothianidin results in decreased expression of KCND3 mRNA |
CTD |
PMID:31626844 |
|
NCBI chr 2:207,923,775...208,140,727
Ensembl chr 2:207,923,775...208,140,727
|
|
G |
Kcnk1 |
potassium two pore domain channel subfamily K member 1 |
decreases expression |
ISO |
clothianidin results in decreased expression of KCNK1 mRNA |
CTD |
PMID:31626844 |
|
NCBI chr19:58,823,836...58,862,926
Ensembl chr19:58,823,814...58,862,926
|
|
G |
Kcnma1 |
potassium calcium-activated channel subfamily M alpha 1 |
decreases expression |
ISO |
clothianidin results in decreased expression of KCNMA1 mRNA |
CTD |
PMID:31626844 |
|
NCBI chr15:344,204...1,048,849
Ensembl chr15:344,360...1,047,956
|
|
G |
Kif7 |
kinesin family member 7 |
increases expression |
ISO |
clothianidin results in increased expression of KIF7 mRNA |
CTD |
PMID:31626844 |
|
NCBI chr 1:141,434,183...141,452,592
Ensembl chr 1:141,434,625...141,451,075
|
|
G |
Kifc3 |
kinesin family member C3 |
increases expression |
ISO |
clothianidin results in increased expression of KIFC3 mRNA |
CTD |
PMID:31626844 |
|
NCBI chr19:10,305,405...10,339,186
Ensembl chr19:10,320,604...10,339,178
|
|
G |
Kit |
KIT proto-oncogene receptor tyrosine kinase |
increases expression |
ISO |
clothianidin results in increased expression of KIT mRNA |
CTD |
PMID:31626844 |
|
NCBI chr14:35,072,131...35,149,638
Ensembl chr14:35,072,108...35,149,610
|
|
G |
Klhdc9 |
kelch domain containing 9 |
decreases expression |
ISO |
clothianidin results in decreased expression of KLHDC9 mRNA |
CTD |
PMID:31626844 |
|
NCBI chr13:89,742,750...89,746,254
Ensembl chr13:89,742,750...89,745,835
|
|
G |
Kpna6 |
karyopherin subunit alpha 6 |
increases expression |
ISO |
clothianidin results in increased expression of KPNA6 mRNA |
CTD |
PMID:31626844 |
|
NCBI chr 5:147,852,738...147,867,600
Ensembl chr 5:147,850,275...147,886,615
|
|
G |
Krt28 |
keratin 28 |
increases expression |
ISO |
clothianidin results in increased expression of KRT28 mRNA |
CTD |
PMID:31626844 |
|
NCBI chr10:87,276,094...87,286,753
Ensembl chr10:87,276,293...87,286,387
|
|
G |
Ksr1 |
kinase suppressor of ras 1 |
decreases expression |
ISO |
clothianidin results in decreased expression of KSR1 mRNA |
CTD |
PMID:31626844 |
|
NCBI chr10:66,323,704...66,342,469 NCBI chr10:66,346,100...66,482,396
Ensembl chr10:66,347,358...66,482,150
|
|
G |
L3mbtl1 |
L3MBTL histone methyl-lysine binding protein 1 |
decreases expression |
ISO |
clothianidin results in decreased expression of L3MBTL1 mRNA |
CTD |
PMID:31626844 |
|
NCBI chr 3:159,316,580...159,348,914
Ensembl chr 3:159,321,310...159,347,631
|
|
G |
Lgals12 |
galectin 12 |
increases expression |
ISO |
clothianidin results in increased expression of LGALS12 mRNA |
CTD |
PMID:31626844 |
|
NCBI chr 1:222,891,626...222,903,728
Ensembl chr 1:222,891,626...222,902,320
|
|
G |
Lgi4 |
leucine-rich repeat LGI family, member 4 |
increases expression |
ISO |
clothianidin results in increased expression of LGI4 mRNA |
CTD |
PMID:31626844 |
|
NCBI chr 1:89,491,588...89,502,939
Ensembl chr 1:89,491,654...89,502,974
|
|
G |
Lim2 |
lens intrinsic membrane protein 2 |
increases expression |
ISO |
clothianidin results in increased expression of LIM2 mRNA |
CTD |
PMID:31626844 |
|
NCBI chr 1:98,495,082...98,501,248
Ensembl chr 1:98,495,082...98,501,249
|
|
G |
LOC100911237 |
zinc finger protein 420-like |
increases expression |
ISO |
clothianidin results in increased expression of ZNF502 mRNA |
CTD |
PMID:31626844 |
|
NCBI chr 1:31,494,043...31,519,034
|
|
G |
LOC102551828 |
uncharacterized LOC102551828 |
decreases expression |
ISO |
clothianidin results in decreased expression of C22ORF31 mRNA |
CTD |
PMID:31626844 |
|
NCBI chr14:85,520,841...85,526,211
|
|
G |
LOC108348145 |
zinc finger protein 7-like |
decreases expression |
ISO |
clothianidin results in decreased expression of ZNF501 mRNA |
CTD |
PMID:31626844 |
|
NCBI chr 7:118,488,332...118,497,048
Ensembl chr 7:118,490,345...118,497,077
|
|
G |
LOC290595 |
hypothetical gene supported by AF152002 |
decreases expression |
ISO |
clothianidin results in decreased expression of C10ORF99 mRNA |
CTD |
PMID:31626844 |
|
NCBI chr16:14,352,998...14,360,604
Ensembl chr16:14,353,459...14,360,555
|
|
G |
LOC691162 |
hypothetical protein LOC691162 |
decreases expression |
ISO |
clothianidin results in decreased expression of C1ORF158 mRNA |
CTD |
PMID:31626844 |
|
NCBI chr 5:162,351,021...162,369,987
Ensembl chr 5:162,351,001...162,369,990
|
|
G |
Lonrf1 |
LON peptidase N-terminal domain and ring finger 1 |
increases expression |
ISO |
clothianidin results in increased expression of LONRF1 mRNA |
CTD |
PMID:31626844 |
|
NCBI chr16:59,564,548...59,594,252
Ensembl chr16:59,564,419...59,593,852
|
|
G |
Lox |
lysyl oxidase |
increases expression |
ISO |
clothianidin results in increased expression of LOX mRNA |
CTD |
PMID:29044138 |
|
NCBI chr18:47,500,320...47,577,819
Ensembl chr18:47,500,330...47,577,819
|
|
G |
Lpar1 |
lysophosphatidic acid receptor 1 |
decreases expression |
ISO |
clothianidin results in decreased expression of LPAR1 mRNA |
CTD |
PMID:31626844 |
|
NCBI chr 5:75,557,038...75,678,067
Ensembl chr 5:75,557,042...75,676,584
|
|
G |
Lrig1 |
leucine-rich repeats and immunoglobulin-like domains 1 |
increases expression |
ISO |
clothianidin results in increased expression of LRIG1 mRNA |
CTD |
PMID:31626844 |
|
NCBI chr 4:126,615,998...126,717,434
Ensembl chr 4:126,617,244...126,644,895
|
|
G |
Lrrc74b |
leucine rich repeat containing 74B |
decreases expression |
ISO |
clothianidin results in decreased expression of LRRC74B mRNA |
CTD |
PMID:31626844 |
|
NCBI chr11:87,417,604...87,434,745
Ensembl chr11:87,418,205...87,434,482
|
|
G |
Luzp2 |
leucine zipper protein 2 |
increases expression |
ISO |
clothianidin results in increased expression of LUZP2 mRNA |
CTD |
PMID:31626844 |
|
NCBI chr 1:111,849,494...112,067,502 NCBI chr 1:113,419,707...113,531,330
Ensembl chr 1:111,849,998...113,527,735
|
|
G |
Lysmd2 |
LysM domain containing 2 |
decreases expression |
ISO |
clothianidin results in decreased expression of LYSMD2 mRNA |
CTD |
PMID:31626844 |
|
NCBI chr 8:82,560,363...82,576,662
Ensembl chr 8:82,560,761...82,577,019
|
|
G |
Mapk1 |
mitogen activated protein kinase 1 |
increases phosphorylation |
ISO |
clothianidin results in increased phosphorylation of MAPK1 protein |
CTD |
PMID:31626844 |
|
NCBI chr11:88,203,863...88,273,301
Ensembl chr11:88,211,599...88,273,254
|
|
G |
Mapk3 |
mitogen activated protein kinase 3 |
increases phosphorylation |
ISO |
clothianidin results in increased phosphorylation of MAPK3 protein |
CTD |
PMID:31626844 |
|
NCBI chr 1:198,192,773...198,198,975
Ensembl chr 1:198,192,773...198,198,975
|
|
G |
Mchr1 |
melanin-concentrating hormone receptor 1 |
increases expression |
ISO |
clothianidin results in increased expression of MCHR1 mRNA |
CTD |
PMID:31626844 |
|
NCBI chr 7:122,456,846...122,459,324
Ensembl chr 7:122,456,799...122,459,960
|
|
G |
Meioc |
meiosis specific with coiled-coil domain |
increases expression |
ISO |
clothianidin results in increased expression of MEIOC mRNA |
CTD |
PMID:31626844 |
|
NCBI chr10:90,622,954...90,641,883
Ensembl chr10:90,622,992...90,642,151
|
|
G |
Mettl16 |
methyltransferase like 16 |
increases expression |
ISO |
clothianidin results in increased expression of METTL16 mRNA |
CTD |
PMID:31626844 |
|
NCBI chr10:61,626,595...61,682,947
Ensembl chr10:61,626,597...61,672,136
|
|
G |
Mettl7a |
methyltransferase like 7A |
decreases expression |
ISO |
clothianidin results in decreased expression of METTL7A mRNA |
CTD |
PMID:29044138 |
|
NCBI chr 7:141,973,447...142,021,344
Ensembl chr 7:141,973,553...141,981,432
|
|
G |
Mical1 |
microtubule associated monooxygenase, calponin and LIM domain containing 1 |
increases expression |
ISO |
clothianidin results in increased expression of MICAL1 mRNA |
CTD |
PMID:31626844 |
|
NCBI chr20:46,199,981...46,211,930
Ensembl chr20:46,199,981...46,211,930
|
|
G |
Micall2 |
MICAL-like 2 |
decreases expression |
ISO |
clothianidin results in decreased expression of MICALL2 mRNA |
CTD |
PMID:29044138 |
|
NCBI chr12:16,988,013...17,016,794
Ensembl chr12:16,988,136...17,016,791
|
|
G |
Mlana |
melan-A |
increases expression |
ISO |
clothianidin results in increased expression of MLANA mRNA |
CTD |
PMID:31626844 |
|
NCBI chr 1:247,869,756...247,883,558
Ensembl chr 1:247,869,756...247,884,442
|
|
G |
Mmp10 |
matrix metallopeptidase 10 |
increases expression |
ISO |
clothianidin results in increased expression of MMP10 mRNA |
CTD |
PMID:31626844 |
|
NCBI chr 8:5,734,348...5,742,243
Ensembl chr 8:5,734,348...5,742,243
|
|
G |
Ms4a2 |
membrane spanning 4-domains A2 |
decreases expression |
ISO |
clothianidin results in decreased expression of MS4A2 mRNA |
CTD |
PMID:29044138 |
|
NCBI chr 1:227,957,363...227,965,312
Ensembl chr 1:227,957,302...227,965,386
|
|
G |
Mss51 |
MSS51 mitochondrial translational activator |
decreases expression |
ISO |
clothianidin results in decreased expression of MSS51 mRNA |
CTD |
PMID:29044138 |
|
NCBI chr15:4,240,203...4,252,072
Ensembl chr15:4,240,203...4,252,072
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G |
Mtg1 |
mitochondrial ribosome-associated GTPase 1 |
decreases expression |
ISO |
clothianidin results in decreased expression of MTG1 mRNA |
CTD |
PMID:29044138 |
|
NCBI chr 1:212,606,753...212,619,493
Ensembl chr 1:212,606,777...212,619,493
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G |
Myl4 |
myosin, light chain 4 |
decreases expression |
ISO |
clothianidin results in decreased expression of MYL4 mRNA |
CTD |
PMID:31626844 |
|
NCBI chr10:92,628,356...92,638,100
Ensembl chr10:92,628,356...92,638,100
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G |
Myl6 |
myosin light chain 6 |
decreases expression |
ISO |
clothianidin results in decreased expression of MYL6 mRNA |
CTD |
PMID:31626844 |
|
NCBI chr 7:2,906,137...2,909,193
Ensembl chr 7:2,906,137...2,909,179
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G |
Mylpf |
myosin light chain, phosphorylatable, fast skeletal muscle |
decreases expression |
ISO |
clothianidin results in decreased expression of MYLPF mRNA |
CTD |
PMID:31626844 |
|
NCBI chr 1:198,655,835...198,658,590
Ensembl chr 1:198,655,742...198,658,583
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G |
Myo3b |
myosin IIIB |
increases expression |
ISO |
clothianidin results in increased expression of MYO3B mRNA |
CTD |
PMID:31626844 |
|
NCBI chr 3:56,355,433...56,717,740
Ensembl chr 3:56,355,431...56,584,547
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|
G |
Myorg |
myogenesis regulating glycosidase |
increases expression |
ISO |
clothianidin results in increased expression of MYORG mRNA |
CTD |
PMID:29044138 |
|
NCBI chr 5:57,873,404...57,882,008
Ensembl chr 5:57,876,498...57,881,944
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G |
Myt1l |
myelin transcription factor 1-like |
increases expression |
ISO |
clothianidin results in increased expression of MYT1L mRNA |
CTD |
PMID:31626844 |
|
NCBI chr 6:48,452,385...48,843,443
Ensembl chr 6:48,452,369...48,857,936
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|
G |
N4bp2l1 |
NEDD4 binding protein 2-like 1 |
increases expression |
ISO |
clothianidin results in increased expression of N4BP2L1 mRNA |
CTD |
PMID:31626844 |
|
NCBI chr12:546,759...576,744
Ensembl chr12:546,760...576,746
|
|
G |
Nadsyn1 |
NAD synthetase 1 |
decreases expression |
ISO |
clothianidin results in decreased expression of NADSYN1 mRNA |
CTD |
PMID:31626844 |
|
NCBI chr 1:216,985,710...217,013,743
Ensembl chr 1:216,985,714...217,013,702
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|
G |
Nasp |
nuclear autoantigenic sperm protein |
decreases expression |
ISO |
clothianidin results in decreased expression of NASP mRNA |
CTD |
PMID:31626844 |
|
NCBI chr 5:135,446,485...135,472,113
Ensembl chr 5:135,446,962...135,472,116
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|
G |
Ndufa10 |
NADH:ubiquinone oxidoreductase subunit A10 |
increases expression |
ISO |
clothianidin results in increased expression of NDUFA10 mRNA |
CTD |
PMID:31626844 |
|
NCBI chr 9:99,617,051...99,651,827
Ensembl chr 9:99,617,052...99,651,813
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|
G |
Neurod4 |
neuronal differentiation 4 |
decreases expression |
ISO |
clothianidin results in decreased expression of NEUROD4 mRNA |
CTD |
PMID:31626844 |
|
NCBI chr 7:9,699,964...9,712,067
Ensembl chr 7:9,699,961...9,711,928
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G |
Ngef |
neuronal guanine nucleotide exchange factor |
increases expression |
ISO |
clothianidin results in increased expression of NGEF mRNA |
CTD |
PMID:31626844 |
|
NCBI chr 9:94,569,286...94,601,852
Ensembl chr 9:94,569,286...94,601,852
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|
G |
Ngfr |
nerve growth factor receptor |
increases expression |
ISO |
clothianidin results in increased expression of NGFR mRNA |
CTD |
PMID:29044138 |
|
NCBI chr10:83,389,828...83,408,061
Ensembl chr10:83,389,847...83,408,061
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|
G |
Nos2 |
nitric oxide synthase 2 |
increases expression |
ISO |
clothianidin results in increased expression of NOS2 mRNA |
CTD |
PMID:31626844 |
|
NCBI chr10:66,188,290...66,221,621
Ensembl chr10:66,189,786...66,313,190
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|
G |
Nr0b2 |
nuclear receptor subfamily 0, group B, member 2 |
decreases expression multiple interactions |
ISO |
clothianidin results in decreased expression of NR0B2 mRNA [clothianidin co-treated with enilconazole] results in decreased expression of NR0B2 mRNA |
CTD |
PMID:32201337 |
|
NCBI chr 5:151,776,004...151,779,319
Ensembl chr 5:151,776,004...151,779,319
|
|
G |
Ntn4 |
netrin 4 |
decreases expression |
ISO |
clothianidin results in decreased expression of NTN4 mRNA |
CTD |
PMID:31626844 |
|
NCBI chr 7:34,533,543...34,649,330
Ensembl chr 7:34,533,543...34,649,481
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|
G |
Nts |
neurotensin |
decreases expression |
ISO |
clothianidin results in decreased expression of NTS mRNA |
CTD |
PMID:31626844 |
|
NCBI chr 7:44,111,594...44,120,998
Ensembl chr 7:44,111,151...44,121,130
|
|
G |
Nxnl2 |
nucleoredoxin-like 2 |
increases expression |
ISO |
clothianidin results in increased expression of NXNL2 mRNA |
CTD |
PMID:31626844 |
|
NCBI chr17:14,053,896...14,058,642
Ensembl chr17:14,053,896...14,058,642
|
|
G |
Nxph2 |
neurexophilin 2 |
increases expression |
ISO |
clothianidin results in increased expression of NXPH2 mRNA |
CTD |
PMID:31626844 |
|
NCBI chr 3:67,027...309,536
Ensembl chr 3:307,204...307,980
|
|
G |
Ocrl |
OCRL, inositol polyphosphate-5-phosphatase |
decreases expression |
ISO |
clothianidin results in decreased expression of OCRL mRNA |
CTD |
PMID:31626844 |
|
NCBI chr X:134,742,226...134,793,411
Ensembl chr X:134,742,356...134,792,618
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|
G |
Olr59 |
olfactory receptor 59 |
increases expression |
ISO |
clothianidin results in increased expression of OR51E2 mRNA |
CTD |
PMID:31626844 |
|
NCBI chr 1:167,906,030...167,940,688
Ensembl chr 1:167,906,061...167,911,961
|
|
G |
Otud6b |
OTU deubiquitinase 6B |
increases expression |
ISO |
clothianidin results in increased expression of OTUD6B mRNA |
CTD |
PMID:29044138 |
|
NCBI chr 5:28,333,019...28,350,093
Ensembl chr 5:28,333,019...28,349,927
|
|
G |
Padi4 |
peptidyl arginine deiminase 4 |
increases expression |
ISO |
clothianidin results in increased expression of PADI4 mRNA |
CTD |
PMID:31626844 |
|
NCBI chr 5:159,260,675...159,293,906
Ensembl chr 5:159,260,675...159,293,673
|
|
G |
Pak5 |
p21 (RAC1) activated kinase 5 |
decreases expression |
ISO |
clothianidin results in decreased expression of PAK5 mRNA |
CTD |
PMID:31626844 |
|
NCBI chr 3:129,042,232...129,357,512
Ensembl chr 3:129,042,742...129,357,491
|
|
G |
Paqr8 |
progestin and adipoQ receptor family member 8 |
decreases expression |
ISO |
clothianidin results in decreased expression of PAQR8 mRNA |
CTD |
PMID:29044138 |
|
NCBI chr 9:27,005,270...27,054,591
Ensembl chr 9:27,034,022...27,051,002
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|
G |
Pbld1 |
phenazine biosynthesis-like protein domain containing 1 |
decreases expression |
ISO |
clothianidin results in decreased expression of PBLD mRNA |
CTD |
PMID:31626844 |
|
NCBI chr20:27,103,300...27,118,650
Ensembl chr20:27,103,317...27,117,663
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|
G |
Pcca |
propionyl-CoA carboxylase subunit alpha |
decreases expression |
ISO |
clothianidin results in decreased expression of PCCA mRNA |
CTD |
PMID:32201337 |
|
NCBI chr15:108,960,509...109,306,879
Ensembl chr15:108,960,562...109,306,603
|
|
G |
Pcsk1 |
proprotein convertase subtilisin/kexin type 1 |
decreases expression |
ISO |
clothianidin results in decreased expression of PCSK1 mRNA |
CTD |
PMID:31626844 |
|
NCBI chr 2:91,450,162...91,497,091
Ensembl chr 2:91,450,162...91,497,091
|
|
G |
Pde10a |
phosphodiesterase 10A |
decreases expression |
ISO |
clothianidin results in decreased expression of PDE10A mRNA |
CTD |
PMID:31626844 |
|
NCBI chr 1:52,360,296...52,544,448
Ensembl chr 1:52,360,296...52,544,450
|
|
G |
Pde1c |
phosphodiesterase 1C |
increases expression |
ISO |
clothianidin results in increased expression of PDE1C mRNA |
CTD |
PMID:31626844 |
|
NCBI chr 4:86,359,762...86,925,044
Ensembl chr 4:86,359,820...86,630,543
|
|
G |
Pde4dip |
phosphodiesterase 4D interacting protein |
increases expression |
ISO |
clothianidin results in increased expression of PDE4DIP mRNA |
CTD |
PMID:31626844 |
|
NCBI chr 2:199,867,965...200,066,034
Ensembl chr 2:199,867,972...200,003,443
|
|
G |
Pdzd7 |
PDZ domain containing 7 |
decreases expression |
ISO |
clothianidin results in decreased expression of PDZD7 mRNA |
CTD |
PMID:29044138 |
|
NCBI chr 1:264,776,393...264,796,206
Ensembl chr 1:264,776,398...264,794,938
|
|
G |
Peli2 |
pellino E3 ubiquitin protein ligase family member 2 |
decreases expression |
ISO |
clothianidin results in decreased expression of PELI2 mRNA |
CTD |
PMID:31626844 |
|
NCBI chr15:24,942,218...25,086,350
Ensembl chr15:24,942,218...25,083,931
|
|
G |
Pheta2 |
PH domain containing endocytic trafficking adaptor 2 |
increases expression |
ISO |
clothianidin results in increased expression of FAM109B mRNA |
CTD |
PMID:31626844 |
|
NCBI chr 7:123,572,153...123,578,590
Ensembl chr 7:123,573,930...123,578,551
|
|
G |
Pik3c2b |
phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 beta |
decreases expression |
ISO |
clothianidin results in decreased expression of PIK3C2B mRNA |
CTD |
PMID:31626844 |
|
NCBI chr13:49,848,939...49,909,404
Ensembl chr13:49,850,189...49,911,202
|
|
G |
Pip5k1c |
phosphatidylinositol-4-phosphate 5-kinase type 1 gamma |
decreases expression |
ISO |
clothianidin results in decreased expression of PIP5K1C mRNA |
CTD |
PMID:31626844 |
|
NCBI chr 7:11,267,207...11,294,291
Ensembl chr 7:11,267,218...11,294,249
|
|
G |
Pip5kl1 |
phosphatidylinositol-4-phosphate 5-kinase-like 1 |
decreases expression |
ISO |
clothianidin results in decreased expression of PIP5KL1 mRNA |
CTD |
PMID:29044138 |
|
NCBI chr 3:11,592,156...11,597,513
Ensembl chr 3:11,593,655...11,597,410
|
|
G |
Pla2g2a |
phospholipase A2 group IIA |
increases expression |
ISO |
clothianidin results in increased expression of PLA2G2A mRNA |
CTD |
PMID:31626844 |
|
NCBI chr 5:157,282,650...157,285,295
Ensembl chr 5:157,282,669...157,285,328
|
|
G |
Plbd1 |
phospholipase B domain containing 1 |
decreases expression |
ISO |
clothianidin results in decreased expression of PLBD1 mRNA |
CTD |
PMID:31626844 |
|
NCBI chr 4:170,564,387...170,620,681
Ensembl chr 4:170,564,367...170,620,703
|
|
G |
Plcd1 |
phospholipase C, delta 1 |
increases expression |
ISO |
clothianidin results in increased expression of PLCD1 mRNA |
CTD |
PMID:31626844 |
|
NCBI chr 8:127,753,514...127,782,070
Ensembl chr 8:127,753,539...127,782,070
|
|
G |
Plcd3 |
phospholipase C, delta 3 |
decreases expression |
ISO |
clothianidin results in decreased expression of PLCD3 mRNA |
CTD |
PMID:31626844 |
|
NCBI chr10:91,164,778...91,186,067
Ensembl chr10:91,164,812...91,186,054
|
|
G |
Plcl1 |
phospholipase C-like 1 |
decreases expression |
ISO |
clothianidin results in decreased expression of PLCL1 mRNA |
CTD |
PMID:31626844 |
|
NCBI chr 9:62,016,112...62,349,244
Ensembl chr 9:62,291,405...62,349,309
|
|
G |
Pllp |
plasmolipin |
increases expression |
ISO |
clothianidin results in increased expression of PLLP mRNA |
CTD |
PMID:31626844 |
|
NCBI chr19:10,731,855...10,752,641
Ensembl chr19:10,731,855...10,752,641
|
|
G |
Pnpla1 |
patatin-like phospholipase domain containing 1 |
increases expression |
ISO |
clothianidin results in increased expression of PNPLA1 mRNA |
CTD |
PMID:31626844 |
|
NCBI chr20:6,101,061...6,143,762
Ensembl chr20:6,102,277...6,143,707
|
|
G |
Polr2m |
RNA polymerase II subunit M |
decreases expression |
ISO |
clothianidin results in decreased expression of POLR2M mRNA |
CTD |
PMID:31626844 |
|
NCBI chr 8:77,985,190...77,992,621
Ensembl chr 8:77,985,190...78,096,390
|
|
G |
Ppp1r3c |
protein phosphatase 1, regulatory subunit 3C |
increases expression |
ISO |
clothianidin results in increased expression of PPP1R3C mRNA |
CTD |
PMID:29044138 |
|
NCBI chr 1:255,371,830...255,376,833
Ensembl chr 1:255,371,810...255,376,833
|
|
G |
Ppp3cc |
protein phosphatase 3 catalytic subunit gamma |
increases expression |
ISO |
clothianidin results in increased expression of PPP3CC mRNA |
CTD |
PMID:31626844 |
|
NCBI chr15:51,896,427...51,968,075
Ensembl chr15:51,896,615...51,967,897
|
|
G |
Prg3 |
proteoglycan 3, pro eosinophil major basic protein 2 |
increases expression |
ISO |
clothianidin results in increased expression of PRG3 mRNA |
CTD |
PMID:31626844 |
|
NCBI chr 3:72,395,194...72,401,254
Ensembl chr 3:72,395,218...72,401,318
|
|
G |
Prlr |
prolactin receptor |
decreases expression |
ISO |
clothianidin results in decreased expression of PRLR mRNA |
CTD |
PMID:29044138 |
|
NCBI chr 2:60,131,410...60,325,686
Ensembl chr 2:60,131,776...60,325,692
|
|
G |
Prnd |
prion like protein doppel |
increases expression |
ISO |
clothianidin results in increased expression of PRND mRNA |
CTD |
PMID:31626844 |
|
NCBI chr 3:124,543,227...124,548,548
Ensembl chr 3:124,545,364...124,545,900
|
|
G |
Prodh2 |
proline dehydrogenase 2 |
increases expression |
ISO |
clothianidin results in increased expression of PRODH2 mRNA |
CTD |
PMID:31626844 |
|
NCBI chr 1:88,955,125...88,968,501
Ensembl chr 1:88,955,135...88,968,501
|
|
G |
Prr5l |
proline rich 5 like |
increases expression |
ISO |
clothianidin results in increased expression of PRR5L mRNA |
CTD |
PMID:31626844 |
|
NCBI chr 3:91,290,207...91,461,208
Ensembl chr 3:91,291,875...91,370,167
|
|
G |
Prxl2b |
peroxiredoxin like 2B |
decreases expression |
ISO |
clothianidin results in decreased expression of PRXL2B mRNA |
CTD |
PMID:31626844 |
|
NCBI chr 5:172,304,799...172,307,402
Ensembl chr 5:172,304,758...172,307,431
|
|
G |
Psmc6 |
proteasome 26S subunit, ATPase 6 |
decreases expression |
ISO |
clothianidin results in decreased expression of PSMC6 mRNA |
CTD |
PMID:31626844 |
|
NCBI chr15:19,667,453...19,688,916
Ensembl chr15:19,667,453...19,688,914
|
|
G |
Ptgfr |
prostaglandin F receptor |
decreases expression |
ISO |
clothianidin results in decreased expression of PTGFR mRNA |
CTD |
PMID:31626844 |
|
NCBI chr 2:257,005,813...257,039,036
Ensembl chr 2:257,005,829...257,038,105
|
|
G |
Ptpn3 |
protein tyrosine phosphatase, non-receptor type 3 |
increases expression |
ISO |
clothianidin results in increased expression of PTPN3 mRNA |
CTD |
PMID:29044138 |
|
NCBI chr 5:74,248,996...74,368,167
Ensembl chr 5:74,248,996...74,368,186
|
|
G |
Ptprb |
protein tyrosine phosphatase, receptor type, B |
decreases expression |
ISO |
clothianidin results in decreased expression of PTPRB mRNA |
CTD |
PMID:31626844 |
|
NCBI chr 7:59,326,484...59,431,114
Ensembl chr 7:59,326,518...59,425,718
|
|
G |
Ptpro |
protein tyrosine phosphatase, receptor type, O |
decreases expression |
ISO |
clothianidin results in decreased expression of PTPRO mRNA |
CTD |
PMID:29044138 |
|
NCBI chr 4:171,250,766...171,461,571
Ensembl chr 4:171,250,818...171,461,677
|
|
G |
Qpct |
glutaminyl-peptide cyclotransferase |
increases expression |
ISO |
clothianidin results in increased expression of QPCT mRNA |
CTD |
PMID:31626844 |
|
NCBI chr 6:1,657,110...1,689,575
Ensembl chr 6:1,657,331...1,689,559
|
|
G |
Rag1 |
recombination activating 1 |
decreases expression |
ISO |
clothianidin results in decreased expression of RAG1 mRNA |
CTD |
PMID:31626844 |
|
NCBI chr 3:91,206,394...91,217,491
Ensembl chr 3:91,206,394...91,217,491
|
|
G |
Rapgefl1 |
Rap guanine nucleotide exchange factor like 1 |
decreases expression |
ISO |
clothianidin results in decreased expression of RAPGEFL1 mRNA |
CTD |
PMID:29044138 |
|
NCBI chr10:86,749,220...86,765,677
Ensembl chr10:86,763,117...86,765,675
|
|
G |
Rbm26 |
RNA binding motif protein 26 |
decreases expression |
ISO |
clothianidin results in decreased expression of RBM26 mRNA |
CTD |
PMID:31626844 |
|
NCBI chr15:89,262,683...89,339,323
Ensembl chr15:89,266,710...89,339,323
|
|
G |
Rbms1 |
RNA binding motif, single stranded interacting protein 1 |
decreases expression |
ISO |
clothianidin results in decreased expression of RBMS1 mRNA |
CTD |
PMID:31626844 |
|
NCBI chr 3:46,802,870...47,025,178
Ensembl chr 3:46,803,355...47,025,128
|
|
G |
Reg3g |
regenerating family member 3 gamma |
increases expression |
ISO |
clothianidin results in increased expression of REG3G mRNA |
CTD |
PMID:31626844 |
|
NCBI chr 4:109,529,679...109,532,234
Ensembl chr 4:109,529,679...109,532,234
|
|
G |
Rfesd |
Rieske (Fe-S) domain containing |
decreases expression |
ISO |
clothianidin results in decreased expression of RFESD mRNA |
CTD |
PMID:31626844 |
|
NCBI chr 2:2,758,382...2,784,366
Ensembl chr 2:2,769,400...2,779,109
|
|
G |
RGD1306227 |
similar to 4833420G17Rik protein |
increases expression |
ISO |
clothianidin results in increased expression of C5ORF34 mRNA |
CTD |
PMID:29044138 |
|
NCBI chr 2:52,333,396...52,355,044
Ensembl chr 2:52,333,396...52,355,042
|
|
G |
RGD1309651 |
similar to 1190005I06Rik protein |
decreases expression |
ISO |
clothianidin results in decreased expression of C16ORF74 mRNA |
CTD |
PMID:31626844 |
|
NCBI chr19:54,184,554...54,210,872
Ensembl chr19:54,184,946...54,210,515
|
|
G |
RGD1559804 |
similar to hypothetical protein 4930474N05 |
increases expression |
ISO |
clothianidin results in increased expression of CDRT15L2 mRNA |
CTD |
PMID:31626844 |
|
NCBI chr16:12,190,742...12,196,263
Ensembl chr16:12,191,697...12,194,118
|
|
G |
RGD1563060 |
similar to AVLV472 |
increases expression |
ISO |
clothianidin results in increased expression of C5ORF46 mRNA |
CTD |
PMID:31626844 |
|
NCBI chr18:38,307,889...38,329,780
Ensembl chr18:38,307,889...38,329,780
|
|
G |
RGD1564149 |
similar to Protein C21orf58 |
decreases expression |
ISO |
clothianidin results in decreased expression of C21ORF58 mRNA |
CTD |
PMID:31626844 |
|
NCBI chr20:12,927,310...12,938,891
Ensembl chr20:12,927,320...12,938,891
|
|
G |
Riiad1 |
regulatory subunit of type II PKA R-subunit domain containing 1 |
decreases expression |
ISO |
clothianidin results in decreased expression of RIIAD1 mRNA |
CTD |
PMID:31626844 |
|
NCBI chr 2:195,703,259...195,712,479
Ensembl chr 2:195,704,505...195,712,461
|
|
G |
Rnd1 |
Rho family GTPase 1 |
increases expression |
ISO |
clothianidin results in increased expression of RND1 mRNA |
CTD |
PMID:29044138 |
|
NCBI chr 7:140,349,138...140,356,209
Ensembl chr 7:140,349,138...140,356,209
|
|
G |
Rp1l1 |
RP1 like 1 |
increases expression |
ISO |
clothianidin results in increased expression of RP1L1 mRNA |
CTD |
PMID:31626844 |
|
NCBI chr15:47,344,380...47,384,461
Ensembl chr15:47,373,120...47,383,508
|
|
G |
Rps29 |
ribosomal protein S29 |
increases expression |
ISO |
clothianidin results in increased expression of RPS29 mRNA |
CTD |
PMID:31626844 |
|
NCBI chr 6:91,455,333...91,456,709
Ensembl chr 6:91,455,333...91,456,696 Ensembl chr 3:91,455,333...91,456,696 Ensembl chr 7:91,455,333...91,456,696
|
|
G |
RT1-Bb |
RT1 class II, locus Bb |
increases expression |
ISO |
clothianidin results in increased expression of HLA-DQB1 mRNA |
CTD |
PMID:31626844 |
|
NCBI chr20:4,043,726...4,049,367
Ensembl chr20:4,039,413...4,049,711
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G |
S100a5 |
S100 calcium binding protein A5 |
decreases expression |
ISO |
clothianidin results in decreased expression of S100A5 mRNA |
CTD |
PMID:31626844 |
|
NCBI chr 2:189,999,669...190,005,877
Ensembl chr 2:190,003,223...190,005,871
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G |
Sash3 |
SAM and SH3 domain containing 3 |
increases expression |
ISO |
clothianidin results in increased expression of SASH3 mRNA |
CTD |
PMID:31626844 |
|
NCBI chr X:134,979,637...134,994,351
Ensembl chr X:134,979,646...134,994,349
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G |
Scn7a |
sodium voltage-gated channel alpha subunit 7 |
decreases expression |
ISO |
clothianidin results in decreased expression of SCN7A mRNA |
CTD |
PMID:31626844 |
|
NCBI chr 3:52,775,779...52,877,365
Ensembl chr 3:52,777,214...52,849,907
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G |
Scnn1b |
sodium channel epithelial 1 subunit beta |
increases expression |
ISO |
clothianidin results in increased expression of SCNN1B mRNA |
CTD |
PMID:31626844 |
|
NCBI chr 1:191,829,547...191,883,991
Ensembl chr 1:191,829,555...191,884,298
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G |
Sema3f |
semaphorin 3F |
decreases expression |
ISO |
clothianidin results in decreased expression of SEMA3F mRNA |
CTD |
PMID:31626844 |
|
NCBI chr 8:116,439,996...116,469,915
Ensembl chr 8:116,437,696...116,469,915
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G |
Serp1 |
stress-associated endoplasmic reticulum protein 1 |
decreases expression |
ISO |
clothianidin results in decreased expression of SERP1 mRNA |
CTD |
PMID:31626844 |
|
NCBI chr 2:148,718,279...148,722,263
Ensembl chr 2:148,718,280...148,722,263
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G |
Serpinc1 |
serpin family C member 1 |
decreases expression |
ISO |
clothianidin results in decreased expression of SERPINC1 mRNA |
CTD |
PMID:31626844 |
|
NCBI chr13:78,806,107...78,820,375
Ensembl chr13:78,805,347...78,833,192
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G |
Serpine1 |
serpin family E member 1 |
decreases expression |
ISO |
clothianidin results in decreased expression of SERPINE1 mRNA |
CTD |
PMID:31626844 |
|
NCBI chr12:22,641,104...22,651,482
Ensembl chr12:22,641,104...22,651,482
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G |
Sgcd |
sarcoglycan, delta |
increases expression |
ISO |
clothianidin results in increased expression of SGCD mRNA |
CTD |
PMID:31626844 |
|
NCBI chr10:32,062,946...32,471,454
Ensembl chr10:32,062,946...32,471,454
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G |
Sgk2 |
serum/glucocorticoid regulated kinase 2 |
decreases expression |
ISO |
clothianidin results in decreased expression of SGK2 mRNA |
CTD |
PMID:29044138 |
|
NCBI chr 3:159,361,313...159,385,843
Ensembl chr 3:159,368,273...159,384,775
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|
G |
Sh3tc1 |
SH3 domain and tetratricopeptide repeats 1 |
increases expression |
ISO |
clothianidin results in increased expression of SH3TC1 mRNA |
CTD |
PMID:29044138 |
|
NCBI chr14:80,184,814...80,229,207
Ensembl chr14:80,195,715...80,229,214
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|
G |
Sipa1l2 |
signal-induced proliferation-associated 1 like 2 |
increases expression |
ISO |
clothianidin results in increased expression of SIPA1L2 mRNA |
CTD |
PMID:29044138 |
|
NCBI chr19:58,236,201...58,399,842
Ensembl chr19:58,236,214...58,399,816
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G |
Slc14a1 |
solute carrier family 14 member 1 (Kidd blood group) |
decreases expression |
ISO |
clothianidin results in decreased expression of SLC14A1 mRNA |
CTD |
PMID:31626844 |
|
NCBI chr18:74,461,064...74,504,475
Ensembl chr18:74,461,055...74,485,139
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G |
Slc17a7 |
solute carrier family 17 member 7 |
decreases expression |
ISO |
clothianidin results in decreased expression of SLC17A7 mRNA |
CTD |
PMID:31626844 |
|
NCBI chr 1:101,161,265...101,172,292
Ensembl chr 1:101,161,252...101,173,174
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G |
Slc22a2 |
solute carrier family 22 member 2 |
decreases activity |
ISO |
clothianidin results in decreased activity of SLC22A2 protein |
CTD |
PMID:31364238 |
|
NCBI chr 1:48,318,025...48,360,219
Ensembl chr 1:48,317,995...48,360,261
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|
G |
Slc22a6 |
solute carrier family 22 member 6 |
decreases activity |
ISO |
clothianidin results in decreased activity of SLC22A6 protein |
CTD |
PMID:31364238 |
|
NCBI chr 1:224,824,809...224,833,284
Ensembl chr 1:224,824,799...224,833,259
|
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G |
Slc22a8 |
solute carrier family 22 member 8 |
decreases activity |
ISO |
clothianidin results in decreased activity of SLC22A8 protein |
CTD |
PMID:31364238 |
|
NCBI chr 1:224,799,444...224,818,482
Ensembl chr 1:224,800,252...224,818,482
|
|
G |
Slc28a1 |
solute carrier family 28 member 1 |
increases expression |
ISO |
clothianidin results in increased expression of SLC28A1 mRNA |
CTD |
PMID:31626844 |
|
NCBI chr 1:142,948,942...142,992,410
Ensembl chr 1:142,950,540...142,992,615
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|
G |
Slc38a9 |
solute carrier family 38, member 9 |
decreases expression |
ISO |
clothianidin results in decreased expression of SLC38A9 mRNA |
CTD |
PMID:31626844 |
|
NCBI chr 2:44,512,556...44,592,793
Ensembl chr 2:44,512,895...44,592,053
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|
G |
Slc45a2 |
solute carrier family 45, member 2 |
decreases expression |
ISO |
clothianidin results in decreased expression of SLC45A2 mRNA |
CTD |
PMID:31626844 |
|
NCBI chr 2:60,966,671...60,999,398
Ensembl chr 2:60,966,789...60,999,398
|
|
G |
Slc47a2 |
solute carrier family 47 member 2 |
decreases activity |
ISO |
clothianidin results in decreased activity of SLC47A2 protein |
CTD |
PMID:31364238 |
|
NCBI chr10:47,587,909...47,631,373
Ensembl chr10:47,588,497...47,630,799
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G |
Slc48a1 |
solute carrier family 48 member 1 |
increases expression |
ISO |
clothianidin results in increased expression of SLC48A1 mRNA |
CTD |
PMID:31626844 |
|
NCBI chr 7:139,271,698...139,279,499
Ensembl chr 7:139,271,698...139,279,499
|
|
G |
Slco1c1 |
solute carrier organic anion transporter family, member 1c1 |
increases expression |
ISO |
clothianidin results in increased expression of SLCO1C1 mRNA |
CTD |
PMID:31626844 |
|
NCBI chr 4:175,729,709...175,776,749
Ensembl chr 4:175,729,726...175,776,808
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|
G |
Sorbs1 |
sorbin and SH3 domain containing 1 |
increases expression |
ISO |
clothianidin results in increased expression of SORBS1 mRNA |
CTD |
PMID:31626844 |
|
NCBI chr 1:259,373,921...259,502,108
Ensembl chr 1:259,376,933...259,484,569
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G |
Spata3 |
spermatogenesis associated 3 |
increases expression |
ISO |
clothianidin results in increased expression of SPATA3 mRNA |
CTD |
PMID:31626844 |
|
NCBI chr 9:93,029,766...93,042,631
Ensembl chr 9:93,030,714...93,042,631
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G |
Spire2 |
spire-type actin nucleation factor 2 |
decreases expression |
ISO |
clothianidin results in decreased expression of SPIRE2 mRNA |
CTD |
PMID:29044138 |
|
NCBI chr19:56,136,904...56,175,500
Ensembl chr19:56,136,904...56,175,500
|
|
G |
Srd5a2 |
steroid 5 alpha-reductase 2 |
increases expression |
ISO |
clothianidin results in increased expression of SRD5A2 mRNA |
CTD |
PMID:31626844 |
|
NCBI chr 6:25,279,635...25,315,501
Ensembl chr 6:25,279,626...25,315,511
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|
G |
Sspo |
SCO-spondin |
decreases expression |
ISO |
clothianidin results in decreased expression of SSPOP mRNA |
CTD |
PMID:29044138 |
|
NCBI chr 4:78,076,695...78,133,676
Ensembl chr 4:78,080,310...78,133,654
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|
G |
Stac2 |
SH3 and cysteine rich domain 2 |
increases expression |
ISO |
clothianidin results in increased expression of STAC2 mRNA |
CTD |
PMID:31626844 |
|
NCBI chr10:85,988,367...86,004,209
Ensembl chr10:85,988,367...86,004,209
|
|
G |
Steap2 |
STEAP2 metalloreductase |
increases expression |
ISO |
clothianidin results in increased expression of STEAP2 mRNA |
CTD |
PMID:31626844 |
|
NCBI chr 4:25,506,604...25,527,088
Ensembl chr 4:25,507,463...25,527,087
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|
G |
Susd4 |
sushi domain containing 4 |
increases expression |
ISO |
clothianidin results in increased expression of SUSD4 mRNA |
CTD |
PMID:31626844 |
|
NCBI chr13:101,181,932...101,307,912
Ensembl chr13:101,181,994...101,307,908
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|
G |
Sycp2 |
synaptonemal complex protein 2 |
decreases expression |
ISO |
clothianidin results in decreased expression of SYCP2 mRNA |
CTD |
PMID:29044138 |
|
NCBI chr 3:173,884,559...173,948,304
Ensembl chr 3:173,884,287...173,947,018
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|
G |
Synpo |
synaptopodin |
decreases expression |
ISO |
clothianidin results in decreased expression of SYNPO mRNA |
CTD |
PMID:29044138 |
|
NCBI chr18:55,863,081...55,921,412
Ensembl chr18:55,865,467...55,916,220
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G |
Tacr1 |
tachykinin receptor 1 |
increases expression |
ISO |
clothianidin results in increased expression of TACR1 mRNA |
CTD |
PMID:31626844 |
|
NCBI chr 4:113,247,236...113,416,139
Ensembl chr 4:113,247,795...113,414,504
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|
G |
Tafa2 |
TAFA chemokine like family member 2 |
decreases expression |
ISO |
clothianidin results in decreased expression of FAM19A2 mRNA |
CTD |
PMID:31626844 |
|
NCBI chr 7:66,017,066...66,496,690
Ensembl chr 7:66,017,086...66,172,360
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|
G |
Tafa5 |
TAFA chemokine like family member 5 |
increases expression |
ISO |
clothianidin results in increased expression of FAM19A5 mRNA |
CTD |
PMID:31626844 |
|
NCBI chr 7:128,500,009...128,728,834
Ensembl chr 7:128,500,011...128,728,928
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|
G |
Tbx2 |
T-box transcription factor 2 |
increases expression |
ISO |
clothianidin results in increased expression of TBX2 mRNA |
CTD |
PMID:29044138 |
|
NCBI chr10:73,278,932...73,290,764
Ensembl chr10:73,279,119...73,289,921
|
|
G |
Tcp10b |
t-complex protein 10b |
increases expression |
ISO |
clothianidin results in increased expression of TCP10L2 mRNA |
CTD |
PMID:31626844 |
|
NCBI chr 1:53,530,992...53,554,113
Ensembl chr 1:53,531,076...53,554,113
|
|
G |
Tecpr1 |
tectonin beta-propeller repeat containing 1 |
decreases expression |
ISO |
clothianidin results in decreased expression of TECPR1 mRNA |
CTD |
PMID:31626844 |
|
NCBI chr12:12,374,132...12,403,382
Ensembl chr12:12,374,790...12,402,552
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|
G |
Tef |
TEF transcription factor, PAR bZIP family member |
increases expression |
ISO |
clothianidin results in increased expression of TEF mRNA |
CTD |
PMID:31626844 |
|
NCBI chr 7:123,033,971...123,058,606
Ensembl chr 7:123,043,503...123,058,604
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|
G |
Tgfbi |
transforming growth factor, beta induced |
increases expression |
ISO |
clothianidin results in increased expression of TGFBI mRNA |
CTD |
PMID:31626844 |
|
NCBI chr17:8,400,123...8,429,338
Ensembl chr17:8,400,146...8,429,338
|
|
G |
Tgm5 |
transglutaminase 5 |
decreases expression |
ISO |
clothianidin results in decreased expression of TGM5 mRNA |
CTD |
PMID:29044138 |
|
NCBI chr 3:112,995,469...113,033,110
Ensembl chr 3:112,995,568...113,023,532
|
|
G |
Tifa |
TRAF-interacting protein with forkhead-associated domain |
increases expression |
ISO |
clothianidin results in increased expression of TIFA mRNA |
CTD |
PMID:31626844 |
|
NCBI chr 2:232,104,394...232,137,425
Ensembl chr 2:232,104,809...232,137,422
|
|
G |
Tlcd4 |
TLC domain containing 4 |
increases expression |
ISO |
clothianidin results in increased expression of TLCD4 mRNA |
CTD |
PMID:29044138 |
|
NCBI chr 2:224,768,034...224,843,198
Ensembl chr 2:224,772,893...224,802,997
|
|
G |
Tlx3 |
T-cell leukemia, homeobox 3 |
decreases expression |
ISO |
clothianidin results in decreased expression of TLX3 mRNA |
CTD |
PMID:31626844 |
|
NCBI chr10:18,128,869...18,131,745
Ensembl chr10:18,129,408...18,131,562
|
|
G |
Tmem273 |
transmembrane protein 273 |
increases expression |
ISO |
clothianidin results in increased expression of C10ORF128 mRNA |
CTD |
PMID:31626844 |
|
NCBI chr16:9,023,387...9,054,664
Ensembl chr16:9,023,387...9,054,664
|
|
G |
Tmem38a |
transmembrane protein 38a |
decreases expression |
ISO |
clothianidin results in decreased expression of TMEM38A mRNA |
CTD |
PMID:29044138 |
|
NCBI chr16:18,960,197...18,974,942
Ensembl chr16:18,959,315...18,974,770
|
|
G |
Tmem71 |
transmembrane protein 71 |
decreases expression |
ISO |
clothianidin results in decreased expression of TMEM71 mRNA |
CTD |
PMID:31626844 |
|
NCBI chr 7:107,264,235...107,392,808
Ensembl chr 7:107,262,929...107,392,972
|
|
G |
Tnf |
tumor necrosis factor |
multiple interactions |
ISO |
clothianidin inhibits the reaction [Lipopolysaccharides results in increased expression of TNF mRNA]; clothianidin inhibits the reaction [Lipopolysaccharides results in increased secretion of TNF protein] |
CTD |
PMID:29044138 |
|
NCBI chr20:5,189,382...5,192,000
Ensembl chr20:5,189,390...5,192,000
|
|
G |
Tnfrsf11b |
TNF receptor superfamily member 11B |
decreases expression |
ISO |
clothianidin results in decreased expression of TNFRSF11B mRNA |
CTD |
PMID:31626844 |
|
NCBI chr 7:93,798,580...93,826,586
Ensembl chr 7:93,798,545...93,826,665
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|
G |
Tnxb |
tenascin XB |
decreases expression |
ISO |
clothianidin results in decreased expression of TNXB mRNA |
CTD |
PMID:29044138 |
|
|
|
G |
Tpm1 |
tropomyosin 1 |
increases expression |
ISO |
clothianidin results in increased expression of TPM1 mRNA |
CTD |
PMID:29044138 |
|
NCBI chr 8:72,814,737...72,841,496
Ensembl chr 8:72,814,740...72,842,228
|
|
G |
Traf4 |
Tnf receptor associated factor 4 |
increases expression |
ISO |
clothianidin results in increased expression of TRAF4 mRNA |
CTD |
PMID:29044138 |
|
NCBI chr10:65,418,688...65,424,802
Ensembl chr10:65,418,700...65,424,802
|
|
G |
Traf6 |
TNF receptor associated factor 6 |
decreases expression |
ISO |
clothianidin results in decreased expression of TRAF6 mRNA |
CTD |
PMID:29044138 |
|
NCBI chr 3:91,252,829...91,271,607
Ensembl chr 3:91,252,829...91,271,607
|
|
G |
Trappc4 |
trafficking protein particle complex 4 |
increases expression |
ISO |
clothianidin results in increased expression of TRAPPC4 mRNA |
CTD |
PMID:31626844 |
|
NCBI chr 8:48,723,755...48,727,182
Ensembl chr 8:48,723,191...48,727,154
|
|
G |
Trim37 |
tripartite motif-containing 37 |
decreases expression |
ISO |
clothianidin results in decreased expression of TRIM37 mRNA |
CTD |
PMID:31626844 |
|
NCBI chr10:74,436,165...74,568,636
Ensembl chr10:74,436,208...74,568,493
|
|
G |
Trmt44 |
tRNA methyltransferase 44 |
increases expression |
ISO |
clothianidin results in increased expression of TRMT44 mRNA |
CTD |
PMID:31626844 |
|
NCBI chr14:80,361,490...80,379,408
Ensembl chr14:80,361,294...80,383,138
|
|
G |
Tssk6 |
testis-specific serine kinase 6 |
decreases expression |
ISO |
clothianidin results in decreased expression of TSSK6 mRNA |
CTD |
PMID:31626844 |
|
NCBI chr16:21,272,282...21,274,756
Ensembl chr16:21,273,387...21,274,688
|
|
G |
Ttc28 |
tetratricopeptide repeat domain 28 |
decreases expression |
ISO |
clothianidin results in decreased expression of TTC28 mRNA |
CTD |
PMID:31626844 |
|
NCBI chr12:51,385,808...51,840,710
Ensembl chr12:51,385,763...51,702,730
|
|
G |
Ttc30b |
tetratricopeptide repeat domain 30B |
decreases expression |
ISO |
clothianidin results in decreased expression of TTC30B mRNA |
CTD |
PMID:31626844 |
|
NCBI chr 3:62,758,754...62,761,325
Ensembl chr 3:62,758,758...62,761,325
|
|
G |
Ttc33 |
tetratricopeptide repeat domain 33 |
decreases expression |
ISO |
clothianidin results in decreased expression of TTC33 mRNA |
CTD |
PMID:31626844 |
|
NCBI chr 2:54,897,320...54,944,241
Ensembl chr 2:54,897,424...54,939,514
|
|
G |
Ttc8 |
tetratricopeptide repeat domain 8 |
decreases expression |
ISO |
clothianidin results in decreased expression of TTC8 mRNA |
CTD |
PMID:31626844 |
|
NCBI chr 6:122,920,308...122,974,525
Ensembl chr 6:122,920,317...122,974,522
|
|
G |
Tubgcp3 |
tubulin, gamma complex associated protein 3 |
increases expression |
ISO |
clothianidin results in increased expression of TUBGCP3 mRNA |
CTD |
PMID:31626844 |
|
NCBI chr16:82,184,362...82,245,041
Ensembl chr16:82,184,387...82,245,041
|
|
G |
Txndc2 |
thioredoxin domain containing 2 |
increases expression |
ISO |
clothianidin results in increased expression of TXNDC2 mRNA |
CTD |
PMID:31626844 |
|
NCBI chr 9:113,354,047...113,358,558
Ensembl chr 9:113,354,053...113,358,526
|
|
G |
Ubap1l |
ubiquitin associated protein 1-like |
decreases expression increases expression |
ISO |
clothianidin results in decreased expression of UBAP1L mRNA clothianidin results in increased expression of UBAP1L mRNA |
CTD |
PMID:29044138 PMID:31626844 |
|
NCBI chr 8:70,876,516...70,895,723
Ensembl chr 8:70,884,491...70,896,501
|
|
G |
Unc119b |
unc-119 lipid binding chaperone B |
increases expression |
ISO |
clothianidin results in increased expression of UNC119B mRNA |
CTD |
PMID:31626844 |
|
NCBI chr12:47,239,663...47,252,286
Ensembl chr12:47,218,969...47,252,286
|
|
G |
Usp43 |
ubiquitin specific peptidase 43 |
decreases expression |
ISO |
clothianidin results in decreased expression of USP43 mRNA |
CTD |
PMID:31626844 |
|
NCBI chr10:54,406,980...54,467,956
Ensembl chr10:54,406,980...54,467,956
|
|
G |
Utrn |
utrophin |
decreases expression |
ISO |
clothianidin results in decreased expression of UTRN mRNA |
CTD |
PMID:31626844 |
|
NCBI chr 1:6,451,809...6,970,040
Ensembl chr 1:6,451,810...6,970,040
|
|
G |
Vamp8 |
vesicle-associated membrane protein 8 |
increases expression |
ISO |
clothianidin results in increased expression of VAMP8 mRNA |
CTD |
PMID:31626844 |
|
NCBI chr 4:100,250,301...100,252,756
Ensembl chr 4:100,250,301...100,252,755
|
|
G |
Vegfd |
vascular endothelial growth factor D |
decreases expression |
ISO |
clothianidin results in decreased expression of VEGFD mRNA |
CTD |
PMID:31626844 |
|
NCBI chr X:31,816,480...31,852,239
Ensembl chr X:31,816,436...31,851,715
|
|
G |
Vps8 |
VPS8 subunit of CORVET complex |
decreases expression |
ISO |
clothianidin results in decreased expression of VPS8 mRNA |
CTD |
PMID:31626844 |
|
NCBI chr11:83,104,912...83,323,606
Ensembl chr11:83,105,064...83,300,409
|
|
G |
Washc4 |
WASH complex subunit 4 |
increases expression |
ISO |
clothianidin results in increased expression of WASHC4 mRNA |
CTD |
PMID:31626844 |
|
NCBI chr 7:26,309,279...26,361,221
Ensembl chr 7:26,311,094...26,361,221
|
|
G |
Whrn |
whirlin |
increases expression |
ISO |
clothianidin results in increased expression of WHRN mRNA |
CTD |
PMID:31626844 |
|
NCBI chr 5:79,235,541...79,317,206
Ensembl chr 5:79,234,950...79,317,206
|
|
G |
Ypel2 |
yippee-like 2 |
increases expression |
ISO |
clothianidin results in increased expression of YPEL2 mRNA |
CTD |
PMID:31626844 |
|
NCBI chr10:74,241,032...74,298,691
Ensembl chr10:74,243,812...74,298,599
|
|
G |
Ypel3 |
yippee-like 3 |
decreases expression |
ISO |
clothianidin results in decreased expression of YPEL3 mRNA |
CTD |
PMID:29044138 |
|
NCBI chr 1:198,210,525...198,213,821
Ensembl chr 1:198,210,525...198,213,816
|
|
G |
Zbtb45 |
zinc finger and BTB domain containing 45 |
decreases expression |
ISO |
clothianidin results in decreased expression of ZBTB45 mRNA |
CTD |
PMID:31626844 |
|
NCBI chr 1:65,563,999...65,568,301
Ensembl chr 1:65,564,173...65,568,300
|
|
G |
Zcchc13 |
zinc finger CCHC-type containing 13 |
decreases expression |
ISO |
clothianidin results in decreased expression of ZCCHC13 mRNA |
CTD |
PMID:31626844 |
|
NCBI chr X:74,497,127...74,498,269
Ensembl chr X:74,497,262...74,497,774
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G |
Zfp18 |
zinc finger protein 18 |
decreases expression |
ISO |
clothianidin results in decreased expression of ZNF18 mRNA |
CTD |
PMID:31626844 |
|
NCBI chr10:52,327,668...52,350,944
Ensembl chr10:52,334,240...52,348,692
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G |
Zfp219 |
zinc finger protein 219 |
decreases expression |
ISO |
clothianidin results in decreased expression of ZNF219 mRNA |
CTD |
PMID:29044138 |
|
NCBI chr15:28,402,412...28,417,379
Ensembl chr15:28,402,415...28,406,046
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G |
Zfp467 |
zinc finger protein 467 |
increases expression |
ISO |
clothianidin results in increased expression of ZNF467 mRNA |
CTD |
PMID:31626844 |
|
NCBI chr 4:78,068,822...78,077,962
Ensembl chr 4:78,067,689...78,075,398
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G |
Zfp521 |
zinc finger protein 521 |
decreases expression |
ISO |
clothianidin results in decreased expression of ZNF521 mRNA |
CTD |
PMID:31626844 |
|
NCBI chr18:5,022,042...5,315,242
Ensembl chr18:5,032,029...5,314,585
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G |
Zfp653 |
zinc finger protein 653 |
decreases expression |
ISO |
clothianidin results in decreased expression of ZNF653 mRNA |
CTD |
PMID:31626844 |
|
NCBI chr 8:23,066,576...23,085,502
Ensembl chr 8:23,066,576...23,084,879
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G |
Zfp865 |
zinc finger protein 865 |
increases expression |
ISO |
clothianidin results in increased expression of ZNF784 mRNA |
CTD |
PMID:31626844 |
|
NCBI chr 1:72,356,880...72,361,358
Ensembl chr 1:72,356,880...72,361,358
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G |
Zkscan7 |
zinc finger with KRAB and SCAN domains 7 |
increases expression |
ISO |
clothianidin results in increased expression of ZKSCAN7 mRNA |
CTD |
PMID:31626844 |
|
NCBI chr 8:131,932,753...131,968,550
Ensembl chr 8:131,933,387...131,950,776
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G |
Zswim4 |
zinc finger, SWIM-type containing 4 |
decreases expression |
ISO |
clothianidin results in decreased expression of ZSWIM4 mRNA |
CTD |
PMID:31626844 |
|
NCBI chr19:25,320,683...25,345,818
Ensembl chr19:25,320,683...25,345,790
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G |
Chrnb2 |
cholinergic receptor nicotinic beta 2 subunit |
multiple interactions |
EXP |
dinotefuran results in increased activity of [NACHRA1 protein co-treated with CHRNB2 protein]; dinotefuran results in increased activity of [NACHRA8 protein co-treated with CHRNB2 protein] |
CTD |
PMID:16981889 PMID:25459289 |
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NCBI chr 2:189,088,570...189,096,785
Ensembl chr 2:189,088,570...189,096,785
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G |
Abcb4 |
ATP binding cassette subfamily B member 4 |
decreases activity |
ISO |
Guanethidine results in decreased activity of ABCB4 protein |
CTD |
PMID:28437613 |
|
NCBI chr 4:22,133,984...22,192,687
Ensembl chr 4:22,133,521...22,425,515
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G |
Acp5 |
acid phosphatase 5, tartrate resistant |
affects expression increases expression |
EXP |
Guanethidine affects the expression of ACP5 protein Guanethidine results in increased expression of ACP5 mRNA |
CTD |
PMID:14527964 |
|
NCBI chr 8:23,142,733...23,149,067
Ensembl chr 8:23,142,734...23,148,396
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G |
Ctsk |
cathepsin K |
increases expression affects expression |
EXP |
Guanethidine results in increased expression of CTSK mRNA Guanethidine affects the expression of CTSK protein |
CTD |
PMID:14527964 |
|
NCBI chr 2:196,655,469...196,666,447
Ensembl chr 2:196,655,469...196,666,446
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G |
Cyp1a2 |
cytochrome P450, family 1, subfamily a, polypeptide 2 |
multiple interactions |
EXP |
Guanethidine inhibits the reaction [Benzo(a)pyrene results in increased activity of CYP1A2 protein] |
CTD |
PMID:16510159 |
|
NCBI chr 8:62,451,360...62,458,244
Ensembl chr 8:62,451,329...62,458,301
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G |
Mmp13 |
matrix metallopeptidase 13 |
increases expression |
EXP |
Guanethidine results in increased expression of MMP13 mRNA |
CTD |
PMID:14527964 |
|
NCBI chr 8:5,522,739...5,533,018
Ensembl chr 8:5,522,739...5,533,018
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G |
Npy |
neuropeptide Y |
decreases expression decreases secretion |
EXP ISO |
Guanethidine results in decreased expression of NPY protein Guanethidine results in decreased secretion of NPY protein |
CTD |
PMID:9460767 PMID:14527964 PMID:15003356 |
|
NCBI chr 4:79,557,856...79,565,059
Ensembl chr 4:79,557,854...79,565,097
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G |
Serpine1 |
serpin family E member 1 |
multiple interactions |
ISO |
Guanethidine inhibits the reaction [Kainic Acid results in increased expression of SERPINE1 mRNA] |
CTD |
PMID:15850565 |
|
NCBI chr12:22,641,104...22,651,482
Ensembl chr12:22,641,104...22,651,482
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G |
Th |
tyrosine hydroxylase |
decreases expression |
EXP |
Guanethidine results in decreased expression of TH protein |
CTD |
PMID:9460767 |
|
NCBI chr 1:216,073,034...216,080,287
Ensembl chr 1:216,073,031...216,080,287
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G |
Vip |
vasoactive intestinal peptide |
decreases expression |
EXP |
Guanethidine results in decreased expression of VIP protein |
CTD |
PMID:14527964 |
|
NCBI chr 1:42,169,307...42,177,582
Ensembl chr 1:42,169,501...42,177,582
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G |
Abl1 |
ABL proto-oncogene 1, non-receptor tyrosine kinase |
multiple interactions |
ISO |
[Methylnitronitrosoguanidine co-treated with Cadmium Chloride] results in increased expression of ABL1 mRNA; [Methylnitronitrosoguanidine co-treated with Okadaic Acid] results in increased expression of ABL1 mRNA; [Methylnitronitrosoguanidine co-treated with Tetradecanoylphorbol Acetate] results in increased expression of ABL1 mRNA |
CTD |
PMID:19840844 |
|
NCBI chr 3:10,041,820...10,145,076
Ensembl chr 3:10,041,826...10,144,388
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G |
Acox2 |
acyl-CoA oxidase 2 |
decreases expression |
EXP |
Methylnitronitrosoguanidine results in decreased expression of ACOX2 mRNA |
CTD |
PMID:15120970 |
|
NCBI chr15:18,449,304...18,481,472
Ensembl chr15:18,451,144...18,481,470
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G |
Adam10 |
ADAM metallopeptidase domain 10 |
increases expression |
ISO |
Methylnitronitrosoguanidine results in increased expression of ADAM10 mRNA |
CTD |
PMID:12634122 |
|
NCBI chr 8:77,107,355...77,237,483
Ensembl chr 8:77,107,536...77,237,483
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G |
Agt |
angiotensinogen |
multiple interactions |
ISO |
[Methylnitronitrosoguanidine co-treated with Cadmium Chloride] results in increased expression of AGT mRNA; [Methylnitronitrosoguanidine co-treated with Okadaic Acid] results in increased expression of AGT mRNA; [Methylnitronitrosoguanidine co-treated with Tetradecanoylphorbol Acetate] results in increased expression of AGT mRNA |
CTD |
PMID:19840844 |
|
NCBI chr19:57,321,594...57,333,460
Ensembl chr19:57,321,640...57,333,433
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G |
Aifm1 |
apoptosis inducing factor, mitochondria associated 1 |
multiple interactions increases localization |
ISO |
benzamide inhibits the reaction [Methylnitronitrosoguanidine results in increased localization of AIFM1 protein]; phenanthridone inhibits the reaction [Methylnitronitrosoguanidine results in increased localization of AIFM1 protein] |
CTD |
PMID:15589979 |
|
NCBI chr X:135,304,063...135,343,062
Ensembl chr X:135,304,066...135,343,087
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G |
Alb |
albumin |
decreases secretion |
EXP |
Methylnitronitrosoguanidine results in decreased secretion of ALB protein |
CTD |
PMID:15772367 |
|
NCBI chr14:19,176,275...19,191,793
Ensembl chr14:19,176,277...19,191,863
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G |
Aldh1a1 |
aldehyde dehydrogenase 1 family, member A1 |
multiple interactions |
ISO |
[Methylnitronitrosoguanidine co-treated with Cadmium Chloride] results in decreased expression of ALDH1A1 mRNA; [Methylnitronitrosoguanidine co-treated with Okadaic Acid] results in decreased expression of ALDH1A1 mRNA; [Methylnitronitrosoguanidine co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of ALDH1A1 mRNA |
CTD |
PMID:19840844 |
|
NCBI chr 1:238,222,689...238,264,381
Ensembl chr 1:238,222,521...238,264,330
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G |
Alpl |
alkaline phosphatase, biomineralization associated |
increases expression |
ISO |
Methylnitronitrosoguanidine results in increased expression of ALPL mRNA |
CTD |
PMID:12634122 |
|
NCBI chr 5:156,086,496...156,141,513
Ensembl chr 5:156,086,497...156,141,537
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G |
Ambp |
alpha-1-microglobulin/bikunin precursor |
decreases expression |
ISO |
Methylnitronitrosoguanidine results in decreased expression of AMBP mRNA |
CTD |
PMID:12773770 |
|
NCBI chr 5:78,975,690...78,986,021
Ensembl chr 5:78,975,678...78,985,990
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G |
Anxa5 |
annexin A5 |
multiple interactions |
ISO |
[Methylnitronitrosoguanidine co-treated with Okadaic Acid] results in increased expression of ANXA5 mRNA |
CTD |
PMID:19840844 |
|
NCBI chr 2:123,162,477...123,194,730
Ensembl chr 2:123,162,461...123,193,130
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G |
Apaf1 |
apoptotic peptidase activating factor 1 |
affects response to substance decreases expression multiple interactions |
ISO |
APAF1 protein affects the susceptibility to Methylnitronitrosoguanidine Methylnitronitrosoguanidine results in decreased expression of APAF1 protein Eugenol inhibits the reaction [Methylnitronitrosoguanidine results in decreased expression of APAF1 protein] |
CTD |
PMID:16019050 PMID:20434464 |
|
NCBI chr 7:31,699,309...31,784,192
Ensembl chr 7:31,699,885...31,784,192
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G |
Apc |
APC regulator of WNT signaling pathway |
increases expression |
ISO |
Methylnitronitrosoguanidine results in increased expression of APC mRNA |
CTD |
PMID:12634122 |
|
NCBI chr18:27,011,710...27,106,323
Ensembl chr18:27,047,382...27,105,531
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G |
App |
amyloid beta precursor protein |
multiple interactions |
ISO |
[Methylnitronitrosoguanidine co-treated with Cadmium Chloride] results in decreased expression of APP mRNA; [Methylnitronitrosoguanidine co-treated with Okadaic Acid] results in decreased expression of APP mRNA; [Methylnitronitrosoguanidine co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of APP mRNA |
CTD |
PMID:19840844 |
|
NCBI chr11:24,425,013...24,641,872
Ensembl chr11:24,425,005...24,641,858
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G |
Araf |
A-Raf proto-oncogene, serine/threonine kinase |
increases expression |
ISO |
Methylnitronitrosoguanidine results in increased expression of ARAF mRNA |
CTD |
PMID:12634122 |
|
NCBI chr X:1,369,534...1,391,603
Ensembl chr X:1,379,194...1,390,873
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G |
Atm |
ATM serine/threonine kinase |
increases response to substance |
ISO |
ATM gene mutant form results in increased susceptibility to Methylnitronitrosoguanidine |
CTD |
PMID:15010311 |
|
NCBI chr 8:58,015,938...58,119,973
Ensembl chr 8:58,015,940...58,120,045
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G |
Atp1b3 |
ATPase Na+/K+ transporting subunit beta 3 |
decreases expression |
ISO |
Methylnitronitrosoguanidine results in decreased expression of ATP1B3 mRNA |
CTD |
PMID:12634122 |
|
NCBI chr 8:104,190,032...104,221,342
Ensembl chr 8:104,190,032...104,221,342
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G |
Atr |
ATR serine/threonine kinase |
multiple interactions |
ISO |
ATR protein promotes the reaction [Methylnitronitrosoguanidine results in increased expression of E2F1 protein]; ATR protein promotes the reaction [Methylnitronitrosoguanidine results in increased expression of E2F3 protein]; ATR protein promotes the reaction [Methylnitronitrosoguanidine results in increased expression of RRM2 mRNA]; ATR protein promotes the reaction [Methylnitronitrosoguanidine results in increased expression of RRM2 protein]; ATR protein promotes the reaction [Methylnitronitrosoguanidine results in increased expression of RRM2B protein]; ATR protein promotes the reaction [Methylnitronitrosoguanidine results in increased expression of TP53 protein] |
CTD |
PMID:26921499 |
|
NCBI chr 8:103,673,578...103,770,886
Ensembl chr 8:103,673,411...103,770,947
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G |
Axl |
Axl receptor tyrosine kinase |
increases expression |
ISO |
Methylnitronitrosoguanidine results in increased expression of AXL mRNA |
CTD |
PMID:12634122 |
|
NCBI chr 1:82,550,892...82,580,761
Ensembl chr 1:82,549,420...82,580,761
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G |
Bad |
BCL2-associated agonist of cell death |
decreases expression decreases phosphorylation multiple interactions |
ISO |
Methylnitronitrosoguanidine results in decreased expression of BAD mRNA Methylnitronitrosoguanidine results in decreased phosphorylation of BAD protein N-(oxo-5,6-dihydrophenanthridin-2-yl)-N,N-dimethylacetamide hydrochloride inhibits the reaction [Methylnitronitrosoguanidine results in decreased phosphorylation of BAD protein] Eugenol inhibits the reaction [Methylnitronitrosoguanidine results in decreased expression of BAD mRNA] |
CTD |
PMID:17828454 PMID:20434464 |
|
NCBI chr 1:222,198,516...222,207,459
Ensembl chr 1:222,198,534...222,207,453
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G |
Bag1 |
BAG cochaperone 1 |
increases expression |
ISO |
Methylnitronitrosoguanidine results in increased expression of BAG1 mRNA |
CTD |
PMID:12634122 |
|
NCBI chr 5:57,254,421...57,267,002
Ensembl chr 5:57,254,421...57,267,002
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G |
Bak1 |
BCL2-antagonist/killer 1 |
multiple interactions |
ISO |
BAK1 protein results in increased susceptibility to [Methylnitronitrosoguanidine co-treated with veliparib] |
CTD |
PMID:18376143 |
|
NCBI chr20:5,609,620...5,618,899
Ensembl chr20:5,609,625...5,618,260
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G |
Bax |
BCL2 associated X, apoptosis regulator |
multiple interactions decreases expression |
EXP ISO |
[Methylnitronitrosoguanidine co-treated with Sodium Chloride] results in decreased expression of BAX protein Methylnitronitrosoguanidine results in decreased expression of BAX mRNA; Methylnitronitrosoguanidine results in decreased expression of BAX protein Eugenol inhibits the reaction [Methylnitronitrosoguanidine results in decreased expression of BAX mRNA]; Eugenol inhibits the reaction [Methylnitronitrosoguanidine results in decreased expression of BAX protein] BAX protein results in increased susceptibility to [Methylnitronitrosoguanidine co-treated with veliparib] |
CTD |
PMID:16030430 PMID:18376143 PMID:20434464 |
|
NCBI chr 1:101,451,801...101,457,207
Ensembl chr 1:101,451,802...101,457,207
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G |
Bcat2 |
branched chain amino acid transaminase 2 |
multiple interactions |
ISO |
[Methylnitronitrosoguanidine co-treated with Okadaic Acid] results in increased expression of BCAT2 mRNA |
CTD |
PMID:19840844 |
|
NCBI chr 1:101,553,900...101,572,103
Ensembl chr 1:101,554,642...101,572,080
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G |
Bcl2 |
BCL2, apoptosis regulator |
decreases expression increases expression multiple interactions |
ISO EXP |
Methylnitronitrosoguanidine results in decreased expression of BCL2 protein Methylnitronitrosoguanidine results in increased expression of BCL2 mRNA; Methylnitronitrosoguanidine results in increased expression of BCL2 protein Eugenol inhibits the reaction [Methylnitronitrosoguanidine results in increased expression of BCL2 mRNA]; Eugenol inhibits the reaction [Methylnitronitrosoguanidine results in increased expression of BCL2 protein] [Methylnitronitrosoguanidine co-treated with Sodium Chloride] results in increased expression of BCL2 protein; [S-allylcysteine co-treated with lycopene] inhibits the reaction [[Methylnitronitrosoguanidine co-treated with Sodium Chloride] results in increased expression of BCL2 protein]; lycopene inhibits the reaction [[Methylnitronitrosoguanidine co-treated with Sodium Chloride] results in increased expression of BCL2 protein]; S-allylcysteine inhibits the reaction [[Methylnitronitrosoguanidine co-treated with Sodium Chloride] results in increased expression of BCL2 protein] |
CTD |
PMID:16019050 PMID:16030430 PMID:20434464 |
|
NCBI chr13:26,605,426...26,769,374
Ensembl chr13:26,605,426...26,769,374
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G |
Bcl2l1 |
Bcl2-like 1 |
multiple interactions increases expression |
ISO |
BCL2L1 protein results in decreased susceptibility to [Methylnitronitrosoguanidine co-treated with veliparib] Methylnitronitrosoguanidine results in increased expression of BCL2L1 mRNA Eugenol inhibits the reaction [Methylnitronitrosoguanidine results in increased expression of BCL2L1 mRNA] |
CTD |
PMID:18376143 PMID:20434464 |
|
NCBI chr 3:148,259,594...148,314,191
Ensembl chr 3:148,259,596...148,313,810
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G |
Bcl2l11 |
BCL2 like 11 |
multiple interactions |
EXP |
[Methylnitronitrosoguanidine co-treated with Sodium Chloride] results in decreased expression of BCL2L11 protein; S-allylcysteine inhibits the reaction [[Methylnitronitrosoguanidine co-treated with Sodium Chloride] results in decreased expression of BCL2L11 protein] |
CTD |
PMID:16030430 |
|
NCBI chr 3:120,726,906...120,764,192
Ensembl chr 3:120,726,906...120,764,192
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G |
Bdnf |
brain-derived neurotrophic factor |
increases expression |
EXP |
Methylnitronitrosoguanidine results in increased expression of BDNF mRNA |
CTD |
PMID:15120970 |
|
NCBI chr 3:100,768,637...100,819,216
Ensembl chr 3:100,768,637...100,819,210
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G |
Bgn |
biglycan |
multiple interactions |
ISO |
[Methylnitronitrosoguanidine co-treated with Cadmium Chloride] results in decreased expression of BGN mRNA; [Methylnitronitrosoguanidine co-treated with Okadaic Acid] results in decreased expression of BGN mRNA; [Methylnitronitrosoguanidine co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of BGN mRNA |
CTD |
PMID:19840844 |
|
NCBI chr X:157,319,042...157,331,204
Ensembl chr X:157,319,046...157,331,204
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G |
Bid |
BH3 interacting domain death agonist |
multiple interactions decreases expression |
ISO |
Eugenol inhibits the reaction [Methylnitronitrosoguanidine results in decreased expression of BID mRNA] |
CTD |
PMID:20434464 |
|
NCBI chr 4:153,439,812...153,465,247
Ensembl chr 4:153,442,218...153,465,203
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G |
Birc2 |
baculoviral IAP repeat-containing 2 |
increases expression |
ISO |
Methylnitronitrosoguanidine results in increased expression of BIRC2 mRNA |
CTD |
PMID:12634122 |
|
NCBI chr 8:6,014,014...6,036,668
Ensembl chr 8:6,013,207...6,034,142
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G |
Blvrb |
biliverdin reductase B |
multiple interactions |
ISO |
[Methylnitronitrosoguanidine co-treated with Okadaic Acid] results in increased expression of BLVRB mRNA |
CTD |
PMID:19840844 |
|
NCBI chr 1:84,256,063...84,273,726
Ensembl chr 1:84,256,159...84,274,075
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G |
Bmp4 |
bone morphogenetic protein 4 |
decreases expression |
ISO |
Methylnitronitrosoguanidine results in decreased expression of BMP4 mRNA |
CTD |
PMID:12773770 |
|
NCBI chr15:20,776,060...20,791,013
Ensembl chr15:20,776,054...20,822,740
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G |
Brca1 |
BRCA1, DNA repair associated |
increases expression |
ISO |
Methylnitronitrosoguanidine results in increased expression of BRCA1 mRNA |
CTD |
PMID:12634122 |
|
NCBI chr10:89,394,821...89,455,093
Ensembl chr10:89,394,803...89,454,681
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G |
Brca2 |
BRCA2, DNA repair associated |
increases expression |
ISO |
Methylnitronitrosoguanidine results in increased expression of BRCA2 mRNA |
CTD |
PMID:12634122 |
|
NCBI chr12:503,660...544,754
Ensembl chr12:504,007...544,748
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G |
Btg2 |
BTG anti-proliferation factor 2 |
decreases expression |
ISO |
Methylnitronitrosoguanidine results in decreased expression of BTG2 protein |
CTD |
PMID:24821435 |
|
NCBI chr13:50,913,185...50,916,944
Ensembl chr13:50,913,180...50,916,982
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G |
C1qb |
complement C1q B chain |
increases expression |
EXP |
Methylnitronitrosoguanidine results in increased expression of C1QB mRNA |
CTD |
PMID:15120970 |
|
NCBI chr 5:155,246,444...155,251,995
Ensembl chr 5:155,246,447...155,252,003
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G |
C1s |
complement C1s |
increases expression |
EXP |
Methylnitronitrosoguanidine results in increased expression of C1S mRNA |
CTD |
PMID:15120970 |
|
NCBI chr 4:157,143,592...157,155,592
Ensembl chr 4:157,143,592...157,155,609
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G |
Calm1 |
calmodulin 1 |
multiple interactions |
ISO |
[Methylnitronitrosoguanidine co-treated with Cadmium Chloride] results in increased expression of CALM1 mRNA; [Methylnitronitrosoguanidine co-treated with Okadaic Acid] results in increased expression of CALM1 mRNA; [Methylnitronitrosoguanidine co-treated with Tetradecanoylphorbol Acetate] results in increased expression of CALM1 mRNA |
CTD |
PMID:19840844 |
|
NCBI chr 6:124,217,241...124,225,292
Ensembl chr 6:124,217,241...124,225,292
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G |
Casp3 |
caspase 3 |
increases activity decreases expression multiple interactions |
ISO EXP |
Methylnitronitrosoguanidine results in increased activity of CASP3 protein Methylnitronitrosoguanidine results in decreased expression of CASP3 mRNA; Methylnitronitrosoguanidine results in decreased expression of CASP3 protein Eugenol inhibits the reaction [Methylnitronitrosoguanidine results in decreased expression of CASP3 mRNA]; Eugenol inhibits the reaction [Methylnitronitrosoguanidine results in decreased expression of CASP3 protein]; N-(oxo-5,6-dihydrophenanthridin-2-yl)-N,N-dimethylacetamide hydrochloride promotes the reaction [Methylnitronitrosoguanidine results in increased activity of CASP3 protein] [Methylnitronitrosoguanidine co-treated with N-(oxo-5,6-dihydrophenanthridin-2-yl)-N,N-dimethylacetamide hydrochloride] results in increased activity of CASP3 protein; [Methylnitronitrosoguanidine co-treated with Sodium Chloride] results in decreased expression of CASP3 protein; [S-allylcysteine co-treated with Lycopene] inhibits the reaction [[Methylnitronitrosoguanidine co-treated with Sodium Chloride] results in decreased expression of CASP3 protein] |
CTD |
PMID:15589979 PMID:16019050 PMID:16030430 PMID:17428624 PMID:20434464 PMID:24476502 |
|
NCBI chr16:48,845,011...48,863,249
Ensembl chr16:48,845,012...48,863,204
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G |
Casp4 |
caspase 4 |
increases expression |
ISO |
Methylnitronitrosoguanidine results in increased expression of CASP4 mRNA |
CTD |
PMID:12634122 |
|
NCBI chr 8:2,616,391...2,651,682
Ensembl chr 8:2,635,851...2,651,652
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G |
Casp8 |
caspase 8 |
multiple interactions |
EXP |
[Methylnitronitrosoguanidine co-treated with Sodium Chloride] results in decreased expression of CASP8 protein; [S-allylcysteine co-treated with lycopene] inhibits the reaction [[Methylnitronitrosoguanidine co-treated with Sodium Chloride] results in decreased expression of CASP8 protein]; lycopene inhibits the reaction [[Methylnitronitrosoguanidine co-treated with Sodium Chloride] results in decreased expression of CASP8 protein]; S-allylcysteine inhibits the reaction [[Methylnitronitrosoguanidine co-treated with Sodium Chloride] results in decreased expression of CASP8 protein] |
CTD |
PMID:16030430 |
|
NCBI chr 9:65,614,142...65,662,624
Ensembl chr 9:65,614,142...65,662,106
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G |
Casp9 |
caspase 9 |
increases activity decreases expression multiple interactions |
ISO |
Methylnitronitrosoguanidine results in increased activity of CASP9 protein Methylnitronitrosoguanidine results in decreased expression of CASP9 protein Eugenol inhibits the reaction [Methylnitronitrosoguanidine results in decreased expression of CASP9 protein] |
CTD |
PMID:15589979 PMID:16019050 PMID:20434464 |
|
NCBI chr 5:160,356,211...160,373,774
Ensembl chr 5:160,355,833...160,373,778
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G |
Cbx5 |
chromobox 5 |
decreases expression |
ISO |
Methylnitronitrosoguanidine results in decreased expression of CBX5 mRNA |
CTD |
PMID:12634122 |
|
NCBI chr 7:144,819,673...144,865,014
Ensembl chr 7:144,819,420...144,837,583
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G |
Ccna1 |
cyclin A1 |
increases expression |
ISO |
Methylnitronitrosoguanidine results in increased expression of CCNA1 mRNA |
CTD |
PMID:12634122 |
|
NCBI chr 2:144,456,689...144,503,570
Ensembl chr 2:144,458,153...144,467,912
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G |
Ccnb1 |
cyclin B1 |
multiple interactions decreases expression increases expression |
EXP ISO |
Eugenol inhibits the reaction [Methylnitronitrosoguanidine results in increased expression of CCNB1 mRNA] Methylnitronitrosoguanidine results in decreased expression of CCNB1 mRNA [Methylnitronitrosoguanidine co-treated with Cadmium Chloride] results in increased expression of CCNB1 mRNA |
CTD |
PMID:11516527 PMID:12135628 PMID:19851710 |
|
NCBI chr 2:30,782,133...30,791,106
Ensembl chr 2:30,783,915...30,791,221
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G |
Ccnd1 |
cyclin D1 |
multiple interactions increases expression |
EXP ISO |
Eugenol inhibits the reaction [Methylnitronitrosoguanidine results in increased expression of CCND1 mRNA] [Methylnitronitrosoguanidine co-treated with Cadmium Chloride] results in increased expression of CCND1 protein Methylnitronitrosoguanidine results in increased expression of CCND1 mRNA; Methylnitronitrosoguanidine results in increased expression of CCND1 protein |
CTD |
PMID:12135628 PMID:19851710 PMID:21628965 |
|
NCBI chr 1:218,090,750...218,100,447
Ensembl chr 1:218,090,750...218,100,325
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G |
Ccng1 |
cyclin G1 |
increases expression |
ISO |
Methylnitronitrosoguanidine results in increased expression of CCNG1 mRNA |
CTD |
PMID:11516527 |
|
NCBI chr10:25,903,925...25,910,298
Ensembl chr10:25,903,911...25,910,325
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G |
Ccnh |
cyclin H |
increases expression |
ISO |
Methylnitronitrosoguanidine results in increased expression of CCNH mRNA |
CTD |
PMID:12634122 |
|
NCBI chr 2:13,593,100...13,613,910
Ensembl chr 2:13,593,100...13,613,910
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G |
Cct2 |
chaperonin containing TCP1 subunit 2 |
multiple interactions |
ISO |
[Methylnitronitrosoguanidine co-treated with Cadmium Chloride] results in increased expression of CCT2 mRNA |
CTD |
PMID:19840844 |
|
NCBI chr 7:60,106,532...60,122,779
Ensembl chr 7:60,109,974...60,122,805
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G |
Cd59 |
CD59 molecule |
increases mutagenesis |
ISO |
Methylnitronitrosoguanidine results in increased mutagenesis of CD59 protein |
CTD |
PMID:17045307 |
|
NCBI chr 3:94,010,481...94,028,660
Ensembl chr 3:94,010,475...94,028,621
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G |
Cd9 |
CD9 molecule |
multiple interactions |
ISO |
[Methylnitronitrosoguanidine co-treated with Cadmium Chloride] results in increased expression of CD9 mRNA; [Methylnitronitrosoguanidine co-treated with Okadaic Acid] results in increased expression of CD9 mRNA; [Methylnitronitrosoguanidine co-treated with Tetradecanoylphorbol Acetate] results in increased expression of CD9 mRNA |
CTD |
PMID:19840844 |
|
NCBI chr 4:157,977,163...158,010,091
Ensembl chr 4:157,977,162...158,010,166
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G |
Cdh1 |
cadherin 1 |
multiple interactions decreases expression |
EXP |
geraniol inhibits the reaction [Methylnitronitrosoguanidine results in decreased expression of CDH1 protein] |
CTD |
PMID:28428697 |
|
NCBI chr19:38,768,467...38,838,395
Ensembl chr19:38,768,467...38,838,395
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G |
Cdh8 |
cadherin 8 |
decreases expression |
ISO |
Methylnitronitrosoguanidine results in decreased expression of CDH8 mRNA |
CTD |
PMID:12634122 |
|
NCBI chr19:6,031,654...6,431,502
Ensembl chr19:6,046,665...6,426,216
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G |
Cdk4 |
cyclin-dependent kinase 4 |
increases expression multiple interactions |
EXP ISO |
Methylnitronitrosoguanidine results in increased expression of CDK4 protein [Methylnitronitrosoguanidine co-treated with Cadmium Chloride] results in increased expression of CDK4 protein |
CTD |
PMID:12135628 PMID:21628965 |
|
NCBI chr 7:70,345,971...70,352,689
Ensembl chr 7:70,349,863...70,352,418
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G |
Cdk5 |
cyclin-dependent kinase 5 |
increases expression |
ISO |
Methylnitronitrosoguanidine results in increased expression of CDK5 mRNA |
CTD |
PMID:12634122 |
|
NCBI chr 4:7,282,945...7,287,427
Ensembl chr 4:7,282,948...7,288,383
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G |
Cdkn1a |
cyclin-dependent kinase inhibitor 1A |
decreases expression multiple interactions |
ISO EXP |
Methylnitronitrosoguanidine results in decreased expression of CDKN1A mRNA Methylnitronitrosoguanidine results in decreased expression of CDKN1A protein Eugenol inhibits the reaction [Methylnitronitrosoguanidine results in decreased expression of CDKN1A protein] |
CTD |
PMID:12634122 PMID:19851710 |
|
NCBI chr20:6,348,422...6,358,864
Ensembl chr20:6,351,458...6,358,864
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G |
Cdkn1b |
cyclin-dependent kinase inhibitor 1B |
decreases expression multiple interactions increases expression |
ISO |
Methylnitronitrosoguanidine results in decreased expression of CDKN1B mRNA Cadmium Chloride inhibits the reaction [Methylnitronitrosoguanidine results in increased expression of CDKN1B protein]; Cadmium Chloride promotes the reaction [Methylnitronitrosoguanidine results in decreased expression of CDKN1B mRNA] |
CTD |
PMID:11516527 PMID:12135628 |
|
NCBI chr 4:168,689,043...168,694,159
Ensembl chr 4:168,689,163...168,693,964
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G |
Cep43 |
centrosomal protein 43 |
increases expression |
ISO |
Methylnitronitrosoguanidine results in increased expression of CEP43 mRNA |
CTD |
PMID:12634122 |
|
NCBI chr 1:53,122,330...53,152,872
Ensembl chr 1:53,122,322...53,152,866
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G |
Chek1 |
checkpoint kinase 1 |
multiple interactions |
ISO |
CHEK1 protein promotes the reaction [Methylnitronitrosoguanidine results in increased expression of E2F3 protein]; CHEK1 protein promotes the reaction [Methylnitronitrosoguanidine results in increased expression of RRM2 mRNA]; CHEK1 protein promotes the reaction [Methylnitronitrosoguanidine results in increased expression of RRM2 protein] |
CTD |
PMID:26921499 |
|
NCBI chr 8:39,181,162...39,201,588
Ensembl chr 8:39,181,163...39,243,882
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G |
Chek2 |
checkpoint kinase 2 |
multiple interactions |
ISO |
CHEK2 protein promotes the reaction [Methylnitronitrosoguanidine results in increased expression of E2F1 protein]; CHEK2 protein promotes the reaction [Methylnitronitrosoguanidine results in increased expression of RRM2B protein]; CHEK2 protein promotes the reaction [Methylnitronitrosoguanidine results in increased expression of TP53 protein] |
CTD |
PMID:26921499 |
|
NCBI chr12:51,845,574...51,878,098
Ensembl chr12:51,845,796...51,877,624
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G |
Ckb |
creatine kinase B |
decreases expression |
ISO |
Methylnitronitrosoguanidine results in decreased expression of CKB mRNA |
CTD |
PMID:12634122 |
|
NCBI chr 6:136,142,956...136,145,838
Ensembl chr 6:136,142,956...136,145,837
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G |
Clta |
clathrin, light chain A |
multiple interactions |
ISO |
[Methylnitronitrosoguanidine co-treated with Cadmium Chloride] results in increased expression of CLTA mRNA; [Methylnitronitrosoguanidine co-treated with Okadaic Acid] results in increased expression of CLTA mRNA; [Methylnitronitrosoguanidine co-treated with Tetradecanoylphorbol Acetate] results in increased expression of CLTA mRNA |
CTD |
PMID:19840844 |
|
NCBI chr 5:59,490,689...59,509,139
Ensembl chr 5:59,491,096...59,509,138
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G |
Col1a2 |
collagen type I alpha 2 chain |
multiple interactions |
ISO |
[Methylnitronitrosoguanidine co-treated with Cadmium Chloride] results in decreased expression of COL1A2 mRNA; [Methylnitronitrosoguanidine co-treated with Okadaic Acid] results in decreased expression of COL1A2 mRNA; [Methylnitronitrosoguanidine co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of COL1A2 mRNA |
CTD |
PMID:19840844 |
|
NCBI chr 4:31,534,225...31,569,152
Ensembl chr 4:31,534,225...31,569,151
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G |
Col6a1 |
collagen type VI alpha 1 chain |
multiple interactions |
ISO |
[Methylnitronitrosoguanidine co-treated with Cadmium Chloride] results in decreased expression of COL6A1 mRNA; [Methylnitronitrosoguanidine co-treated with Okadaic Acid] results in decreased expression of COL6A1 mRNA; [Methylnitronitrosoguanidine co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of COL6A1 mRNA |
CTD |
PMID:19840844 |
|
NCBI chr20:12,657,913...12,676,370
Ensembl chr20:12,658,065...12,675,561
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G |
Col8a1 |
collagen type VIII alpha 1 chain |
multiple interactions |
ISO |
[Methylnitronitrosoguanidine co-treated with Cadmium Chloride] results in decreased expression of COL8A1 mRNA; [Methylnitronitrosoguanidine co-treated with Okadaic Acid] results in decreased expression of COL8A1 mRNA; [Methylnitronitrosoguanidine co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of COL8A1 mRNA |
CTD |
PMID:19840844 |
|
NCBI chr11:44,877,690...45,006,203
Ensembl chr11:44,877,859...45,007,891
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G |
Cox6a1 |
cytochrome c oxidase subunit 6A1 |
multiple interactions |
ISO |
[Methylnitronitrosoguanidine co-treated with Tetradecanoylphorbol Acetate] results in increased expression of COX6A1 mRNA |
CTD |
PMID:19840844 |
|
NCBI chr12:47,024,442...47,027,495
Ensembl chr12:47,024,442...47,027,495
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G |
Cox8a |
cytochrome c oxidase subunit 8A |
multiple interactions |
ISO |
[Methylnitronitrosoguanidine co-treated with Tetradecanoylphorbol Acetate] results in increased expression of COX8A mRNA |
CTD |
PMID:19840844 |
|
NCBI chr 1:222,466,575...222,468,896
Ensembl chr 1:222,466,575...222,468,896
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G |
Ctnnb1 |
catenin beta 1 |
multiple interactions increases expression |
EXP |
geraniol inhibits the reaction [Methylnitronitrosoguanidine results in increased expression of CTNNB1 mRNA] |
CTD |
PMID:28428697 |
|
NCBI chr 8:129,601,511...129,628,378
Ensembl chr 8:129,617,812...129,627,372
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G |
Ctsb |
cathepsin B |
multiple interactions |
ISO |
[Methylnitronitrosoguanidine co-treated with Cadmium Chloride] results in decreased expression of CTSB mRNA; [Methylnitronitrosoguanidine co-treated with Okadaic Acid] results in decreased expression of CTSB mRNA; [Methylnitronitrosoguanidine co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of CTSB mRNA |
CTD |
PMID:19840844 |
|
NCBI chr15:46,316,741...46,337,613
Ensembl chr15:46,316,741...46,337,612
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G |
Ctsl |
cathepsin L |
multiple interactions |
ISO |
[Methylnitronitrosoguanidine co-treated with Cadmium Chloride] results in increased expression of CTSL mRNA; [Methylnitronitrosoguanidine co-treated with Okadaic Acid] results in increased expression of CTSL mRNA; [Methylnitronitrosoguanidine co-treated with Tetradecanoylphorbol Acetate] results in increased expression of CTSL mRNA |
CTD |
PMID:19840844 |
|
NCBI chr17:1,873,105...1,879,266
Ensembl chr17:1,872,848...1,879,279
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G |
Cxcl12 |
C-X-C motif chemokine ligand 12 |
multiple interactions |
ISO |
[Methylnitronitrosoguanidine co-treated with Okadaic Acid] results in increased expression of CXCL12 mRNA |
CTD |
PMID:19840844 |
|
NCBI chr 4:149,261,044...149,273,891
Ensembl chr 4:149,261,044...149,273,891
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G |
Cxcr4 |
C-X-C motif chemokine receptor 4 |
decreases expression |
ISO |
Methylnitronitrosoguanidine results in decreased expression of CXCR4 mRNA |
CTD |
PMID:12634122 |
|
NCBI chr13:45,314,952...45,318,856
Ensembl chr13:45,314,933...45,318,878
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G |
Cyb561d2 |
cytochrome b561 family, member D2 |
decreases expression |
ISO |
Methylnitronitrosoguanidine results in decreased expression of CYB561D2 mRNA |
CTD |
PMID:12634122 |
|
NCBI chr 8:116,295,328...116,297,879
Ensembl chr 8:116,295,329...116,297,858
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G |
Cycs |
cytochrome c, somatic |
multiple interactions decreases expression |
ISO |
Eugenol inhibits the reaction [Methylnitronitrosoguanidine results in decreased expression of CYCS mRNA]; Eugenol inhibits the reaction [Methylnitronitrosoguanidine results in decreased expression of CYCS protein] Methylnitronitrosoguanidine results in decreased expression of CYCS mRNA; Methylnitronitrosoguanidine results in decreased expression of CYCS protein |
CTD |
PMID:20434464 |
|
NCBI chr 4:80,331,226...80,333,326
Ensembl chr 4:80,331,227...80,333,326
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G |
Dcn |
decorin |
decreases expression |
EXP |
Methylnitronitrosoguanidine results in decreased expression of DCN mRNA |
CTD |
PMID:15120970 |
|
NCBI chr 7:38,742,250...38,782,282
Ensembl chr 7:38,742,051...38,782,323
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G |
Deaf1 |
DEAF1 transcription factor |
decreases expression |
ISO |
Methylnitronitrosoguanidine results in decreased expression of DEAF1 mRNA |
CTD |
PMID:12634122 |
|
NCBI chr 1:214,283,787...214,317,466
Ensembl chr 1:214,283,790...214,317,466
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G |
Dek |
DEK proto-oncogene |
increases expression |
ISO |
Methylnitronitrosoguanidine results in increased expression of DEK mRNA |
CTD |
PMID:12634122 |
|
NCBI chr17:17,965,872...17,987,836
Ensembl chr17:17,965,881...17,987,834
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G |
Dlg1 |
discs large MAGUK scaffold protein 1 |
multiple interactions |
ISO |
[Methylnitronitrosoguanidine co-treated with Cadmium Chloride] results in decreased expression of DLG1 mRNA; [Methylnitronitrosoguanidine co-treated with Okadaic Acid] results in decreased expression of DLG1 mRNA; [Methylnitronitrosoguanidine co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of DLG1 mRNA |
CTD |
PMID:19840844 |
|
NCBI chr11:72,164,566...72,378,895
Ensembl chr11:72,163,749...72,378,895
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G |
Dstn |
destrin, actin depolymerizing factor |
increases expression |
ISO |
Methylnitronitrosoguanidine results in increased expression of DSTN mRNA |
CTD |
PMID:12634122 |
|
NCBI chr 3:138,024,508...138,051,304
Ensembl chr 3:138,024,508...138,051,298
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G |
Dut |
deoxyuridine triphosphatase |
affects localization increases secretion |
ISO |
Methylnitronitrosoguanidine affects the localization of DUT protein Methylnitronitrosoguanidine results in increased secretion of DUT protein |
CTD |
PMID:21658424 |
|
NCBI chr 3:117,514,399...117,525,450
Ensembl chr 3:117,514,444...117,525,446
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G |
E2f1 |
E2F transcription factor 1 |
increases expression multiple interactions |
ISO |
Methylnitronitrosoguanidine results in increased expression of E2F1 protein ATR protein promotes the reaction [Methylnitronitrosoguanidine results in increased expression of E2F1 protein]; CHEK2 protein promotes the reaction [Methylnitronitrosoguanidine results in increased expression of E2F1 protein]; E2F1 protein promotes the reaction [Methylnitronitrosoguanidine results in increased expression of RRM2B mRNA]; Methylnitronitrosoguanidine promotes the reaction [E2F1 protein binds to RRM2 promoter]; Methylnitronitrosoguanidine promotes the reaction [E2F1 protein results in increased expression of RRM2 mRNA] |
CTD |
PMID:26921499 |
|
NCBI chr 3:150,062,895...150,073,721
Ensembl chr 3:150,047,826...150,073,721
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G |
E2f3 |
E2F transcription factor 3 |
multiple interactions |
ISO |
[[Methylnitronitrosoguanidine results in increased phosphorylation of and results in increased stability of and results in increased expression of E2F3 protein] which results in increased expression of RRM2 mRNA] inhibits the reaction [Methylnitronitrosoguanidine results in increased expression of H2AX protein modified form]; [Methylnitronitrosoguanidine results in increased phosphorylation of and results in increased stability of and results in increased expression of E2F3 protein] which results in increased expression of RRM2 mRNA; ATR protein promotes the reaction [Methylnitronitrosoguanidine results in increased expression of E2F3 protein]; CHEK1 protein promotes the reaction [Methylnitronitrosoguanidine results in increased expression of E2F3 protein]; CHIR-124 inhibits the reaction [Methylnitronitrosoguanidine results in increased expression of E2F3 protein]; E2F3 protein inhibits the reaction [Methylnitronitrosoguanidine results in increased expression of H2AX protein modified form]; E2F3 protein promotes the reaction [Methylnitronitrosoguanidine results in increased expression of RRM2 mRNA]; E2F3 protein promotes the reaction [Methylnitronitrosoguanidine results in increased expression of RRM2 protein]; E2F3 protein promotes the reaction [Methylnitronitrosoguanidine results in increased expression of RRM2B mRNA]; Methylnitronitrosoguanidine promotes the reaction [E2F3 protein binds to RRM2 promoter]; Methylnitronitrosoguanidine promotes the reaction [E2F3 protein results in increased expression of RRM2 mRNA]; Methylnitronitrosoguanidine results in increased phosphorylation of and results in increased stability of and results in increased expression of E2F3 protein; NFYB protein promotes the reaction [Methylnitronitrosoguanidine promotes the reaction [E2F3 protein binds to RRM2 promoter]]; NFYB protein promotes the reaction [Methylnitronitrosoguanidine promotes the reaction [E2F3 protein results in increased expression of RRM2 mRNA]] |
CTD |
PMID:26921499 |
|
NCBI chr17:36,334,136...36,408,831
Ensembl chr17:36,334,147...36,408,831
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G |
Egf |
epidermal growth factor |
affects activity multiple interactions |
ISO |
Methylnitronitrosoguanidine affects the activity of EGF protein Methylnitronitrosoguanidine inhibits the reaction [EGF protein results in increased activity of HRAS protein]; Methylnitronitrosoguanidine inhibits the reaction [EGF protein results in increased phosphorylation of EGFR protein] |
CTD |
PMID:15708576 |
|
NCBI chr 2:68,820,616...68,895,537
|
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G |
Egfr |
epidermal growth factor receptor |
affects localization multiple interactions |
ISO |
Methylnitronitrosoguanidine affects the localization of EGFR protein Methylnitronitrosoguanidine inhibits the reaction [EGF protein results in increased phosphorylation of EGFR protein] |
CTD |
PMID:15708576 |
|
NCBI chr14:99,919,485...100,104,136
Ensembl chr14:99,919,485...100,098,796
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G |
Egr1 |
early growth response 1 |
multiple interactions |
ISO |
[Methylnitronitrosoguanidine co-treated with Cadmium Chloride] results in increased expression of EGR1 mRNA |
CTD |
PMID:19840844 |
|
NCBI chr18:27,657,903...27,660,101
Ensembl chr18:27,657,628...27,661,429
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G |
Eif1 |
eukaryotic translation initiation factor 1 |
multiple interactions |
ISO |
[Methylnitronitrosoguanidine co-treated with Tetradecanoylphorbol Acetate] results in increased expression of EIF1 mRNA |
CTD |
PMID:19840844 |
|
NCBI chr10:88,227,455...88,229,546
Ensembl chr10:88,227,360...88,229,765
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G |
Eif3e |
eukaryotic translation initiation factor 3 subunit E |
increases expression |
ISO |
Methylnitronitrosoguanidine results in increased expression of EIF3E mRNA |
CTD |
PMID:12634122 |
|
NCBI chr 7:82,997,694...83,037,231
|
|
G |
Eif5 |
eukaryotic translation initiation factor 5 |
decreases expression |
ISO |
Methylnitronitrosoguanidine results in decreased expression of EIF5 mRNA |
CTD |
PMID:12634122 |
|
NCBI chr 6:136,002,983...136,011,409
Ensembl chr 6:136,004,214...136,011,406
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G |
Eif5a |
eukaryotic translation initiation factor 5A |
multiple interactions |
ISO |
[Methylnitronitrosoguanidine co-treated with Cadmium Chloride] results in increased expression of EIF5A mRNA |
CTD |
PMID:19840844 |
|
NCBI chr10:56,527,075...56,531,615
Ensembl chr10:56,527,085...56,531,483
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|
G |
Elk3 |
ETS transcription factor ELK3 |
increases expression |
ISO |
Methylnitronitrosoguanidine results in increased expression of ELK3 mRNA |
CTD |
PMID:12634122 |
|
NCBI chr 7:34,086,213...34,149,601
Ensembl chr 7:34,086,220...34,121,694
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G |
Emp1 |
epithelial membrane protein 1 |
increases expression |
ISO |
Methylnitronitrosoguanidine results in increased expression of EMP1 mRNA |
CTD |
PMID:12634122 |
|
NCBI chr 4:169,161,076...169,181,967
Ensembl chr 4:169,147,243...169,181,966
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|
G |
Enpp2 |
ectonucleotide pyrophosphatase/phosphodiesterase 2 |
increases expression |
EXP |
Methylnitronitrosoguanidine results in increased expression of ENPP2 mRNA |
CTD |
PMID:15120970 |
|
NCBI chr 7:94,479,931...94,563,086
Ensembl chr 7:94,480,396...94,563,001
|
|
G |
Epcam |
epithelial cell adhesion molecule |
increases expression |
ISO |
Methylnitronitrosoguanidine results in increased expression of EPCAM mRNA |
CTD |
PMID:12634122 |
|
NCBI chr 6:11,282,194...11,308,870
Ensembl chr 6:11,281,964...11,298,216
|
|
G |
Epha1 |
Eph receptor A1 |
increases expression |
ISO |
Methylnitronitrosoguanidine results in increased expression of EPHA1 mRNA |
CTD |
PMID:12634122 |
|
NCBI chr 4:71,749,100...71,763,681
Ensembl chr 4:71,749,242...71,763,679
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G |
Ephb3 |
Eph receptor B3 |
decreases expression |
ISO |
Methylnitronitrosoguanidine results in decreased expression of EPHB3 mRNA |
CTD |
PMID:12634122 |
|
NCBI chr11:83,527,960...83,546,742
Ensembl chr11:83,527,962...83,546,674
|
|
G |
Eps8 |
epidermal growth factor receptor pathway substrate 8 |
multiple interactions |
ISO |
[Methylnitronitrosoguanidine co-treated with Cadmium Chloride] results in increased expression of EPS8 mRNA |
CTD |
PMID:19840844 |
|
NCBI chr 4:171,475,155...171,645,620
Ensembl chr 4:171,475,567...171,591,882
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G |
Erbb2 |
erb-b2 receptor tyrosine kinase 2 |
increases expression |
ISO |
Methylnitronitrosoguanidine results in increased expression of ERBB2 mRNA |
CTD |
PMID:12634122 |
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NCBI chr10:86,367,596...86,391,728
Ensembl chr10:86,367,596...86,391,728
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G |
Erbb4 |
erb-b2 receptor tyrosine kinase 4 |
increases expression |
ISO |
Methylnitronitrosoguanidine results in increased expression of ERBB4 mRNA |
CTD |
PMID:12634122 |
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NCBI chr 9:75,021,790...76,178,936
Ensembl chr 9:75,021,790...75,528,644
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G |
Esr2 |
estrogen receptor 2 |
increases expression |
EXP |
Methylnitronitrosoguanidine results in increased expression of ESR2 mRNA; Methylnitronitrosoguanidine results in increased expression of ESR2 protein |
CTD |
PMID:21628965 PMID:22330348 |
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NCBI chr 6:99,163,953...99,214,711
Ensembl chr 6:99,164,357...99,214,251
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G |
Ets1 |
ETS proto-oncogene 1, transcription factor |
increases expression |
ISO |
Methylnitronitrosoguanidine results in increased expression of ETS1 mRNA |
CTD |
PMID:12634122 |
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NCBI chr 8:33,756,634...33,879,625
Ensembl chr 8:33,816,386...33,879,625
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G |
Faslg |
Fas ligand |
decreases expression |
ISO |
Methylnitronitrosoguanidine results in decreased expression of FASLG protein |
CTD |
PMID:24821435 |
|
NCBI chr13:79,696,811...79,717,581
Ensembl chr13:79,698,445...79,705,705
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G |
Fasn |
fatty acid synthase |
increases expression |
ISO |
Methylnitronitrosoguanidine results in increased expression of FASN mRNA |
CTD |
PMID:12634122 |
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NCBI chr10:109,987,735...110,005,901
Ensembl chr10:109,987,735...110,005,901
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G |
Fau |
FAU, ubiquitin like and ribosomal protein S30 fusion |
multiple interactions |
ISO |
[Methylnitronitrosoguanidine co-treated with Cadmium Chloride] results in increased expression of FAU mRNA; [Methylnitronitrosoguanidine co-treated with Okadaic Acid] results in increased expression of FAU mRNA; [Methylnitronitrosoguanidine co-treated with Tetradecanoylphorbol Acetate] results in increased expression of FAU mRNA |
CTD |
PMID:19840844 |
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NCBI chr 1:221,420,312...221,421,827
Ensembl chr 1:221,420,271...221,421,842
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G |
Fcer1a |
Fc fragment of IgE receptor Ia |
increases expression |
EXP |
Methylnitronitrosoguanidine results in increased expression of FCER1A mRNA |
CTD |
PMID:15120970 |
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NCBI chr13:91,727,253...91,737,106
Ensembl chr13:91,730,925...91,737,053
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G |
Fcgr2a |
Fc fragment of IgG receptor IIa |
increases expression |
EXP |
Methylnitronitrosoguanidine results in increased expression of FCGR3 mRNA |
CTD |
PMID:15120970 |
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NCBI chr13:91,146,878...91,163,691
Ensembl chr13:91,168,973...91,198,036 Ensembl chr13:91,168,973...91,198,036
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G |
Fcgrt |
Fc fragment of IgG receptor and transporter |
decreases expression |
ISO |
Methylnitronitrosoguanidine results in decreased expression of FCGRT mRNA |
CTD |
PMID:12634122 |
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NCBI chr 1:101,086,872...101,096,159
Ensembl chr 1:101,086,877...101,095,594
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G |
Fes |
FES proto-oncogene, tyrosine kinase |
increases expression |
ISO |
Methylnitronitrosoguanidine results in increased expression of FES mRNA |
CTD |
PMID:12634122 |
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NCBI chr 1:142,174,648...142,183,884
Ensembl chr 1:142,174,648...142,183,884
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G |
Fgf10 |
fibroblast growth factor 10 |
increases expression |
EXP |
Methylnitronitrosoguanidine results in increased expression of FGF10 mRNA |
CTD |
PMID:15120970 |
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NCBI chr 2:51,673,480...51,747,533
Ensembl chr 2:51,672,722...51,750,369
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G |
Flt1 |
Fms related receptor tyrosine kinase 1 |
multiple interactions increases expression |
EXP |
Eugenol inhibits the reaction [Methylnitronitrosoguanidine results in increased expression of FLT1 mRNA] |
CTD |
PMID:20434464 |
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NCBI chr12:9,033,993...9,205,886
Ensembl chr12:9,034,308...9,205,905
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G |
Fosl1 |
FOS like 1, AP-1 transcription factor subunit |
decreases expression multiple interactions |
ISO |
Methylnitronitrosoguanidine results in decreased expression of FOSL1 mRNA Methylnitronitrosoguanidine promotes the reaction [[FOSL1 protein binds to JUNB protein] which binds to RRM2 promoter]; Methylnitronitrosoguanidine promotes the reaction [[FOSL1 protein binds to JUNB protein] which results in increased expression of RRM2 mRNA]; Methylnitronitrosoguanidine promotes the reaction [FOSL1 protein binds to RRM2 promoter]; Methylnitronitrosoguanidine promotes the reaction [FOSL1 protein results in increased expression of RRM2 mRNA] |
CTD |
PMID:12634122 PMID:26921499 |
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NCBI chr 1:220,826,560...220,835,066
Ensembl chr 1:220,826,560...220,835,066
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G |
Fst |
follistatin |
increases expression |
EXP |
Methylnitronitrosoguanidine results in increased expression of FST mRNA |
CTD |
PMID:15120970 |
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NCBI chr 2:46,537,589...46,544,813
Ensembl chr 2:46,538,700...46,544,457
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G |
Fstl1 |
follistatin-like 1 |
multiple interactions |
ISO |
[Methylnitronitrosoguanidine co-treated with Cadmium Chloride] results in decreased expression of FSTL1 mRNA; [Methylnitronitrosoguanidine co-treated with Okadaic Acid] results in decreased expression of FSTL1 mRNA; [Methylnitronitrosoguanidine co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of FSTL1 mRNA |
CTD |
PMID:19840844 |
|
NCBI chr11:65,791,196...65,845,721
Ensembl chr11:65,782,567...65,845,418
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G |
Fyn |
FYN proto-oncogene, Src family tyrosine kinase |
increases expression |
ISO |
Methylnitronitrosoguanidine results in increased expression of FYN mRNA |
CTD |
PMID:12634122 |
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NCBI chr20:44,436,354...44,630,316
Ensembl chr20:44,436,403...44,630,317
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G |
Gadd45a |
growth arrest and DNA-damage-inducible, alpha |
decreases expression multiple interactions |
EXP |
Methylnitronitrosoguanidine results in decreased expression of GADD45A mRNA Eugenol inhibits the reaction [Methylnitronitrosoguanidine results in decreased expression of GADD45A mRNA] |
CTD |
PMID:19851710 |
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NCBI chr 4:97,782,512...97,784,814
Ensembl chr 4:97,782,512...97,784,842
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G |
Gcgr |
glucagon receptor |
decreases expression |
EXP |
Methylnitronitrosoguanidine results in decreased expression of GCGR mRNA |
CTD |
PMID:15120970 |
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NCBI chr10:109,707,863...109,716,253
Ensembl chr10:109,707,962...109,716,128
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G |
Gdf15 |
growth differentiation factor 15 |
increases expression |
ISO |
Methylnitronitrosoguanidine results in increased expression of GDF15 mRNA |
CTD |
PMID:12634122 PMID:12773770 |
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NCBI chr16:20,555,395...20,557,978
Ensembl chr16:20,555,395...20,557,978
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G |
Gja1 |
gap junction protein, alpha 1 |
multiple interactions |
ISO |
[Methylnitronitrosoguanidine co-treated with Cadmium Chloride] results in decreased expression of GJA1 mRNA; [Methylnitronitrosoguanidine co-treated with Okadaic Acid] results in decreased expression of GJA1 mRNA; [Methylnitronitrosoguanidine co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of GJA1 mRNA |
CTD |
PMID:19840844 |
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NCBI chr20:37,876,650...37,889,097
Ensembl chr20:37,876,650...37,889,089
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G |
Gjb2 |
gap junction protein, beta 2 |
increases expression |
EXP |
Methylnitronitrosoguanidine results in increased expression of GJB2 mRNA |
CTD |
PMID:15120970 |
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NCBI chr15:37,377,313...37,394,494
Ensembl chr15:37,377,316...37,383,277
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G |
Gpc4 |
glypican 4 |
multiple interactions |
ISO |
[Methylnitronitrosoguanidine co-treated with Cadmium Chloride] results in decreased expression of GPC4 mRNA; [Methylnitronitrosoguanidine co-treated with Okadaic Acid] results in decreased expression of GPC4 mRNA; [Methylnitronitrosoguanidine co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of GPC4 mRNA |
CTD |
PMID:19840844 |
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NCBI chr X:139,354,325...139,464,876
Ensembl chr X:139,354,155...139,464,798
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G |
Gss |
glutathione synthetase |
decreases expression |
ISO |
Methylnitronitrosoguanidine results in decreased expression of GSS mRNA |
CTD |
PMID:12634122 |
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NCBI chr 3:151,076,254...151,106,557
Ensembl chr 3:151,076,254...151,106,557
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G |
Gstm2 |
glutathione S-transferase mu 2 |
multiple interactions |
ISO |
[Methylnitronitrosoguanidine co-treated with Cadmium Chloride] results in decreased expression of GSTM2 mRNA; [Methylnitronitrosoguanidine co-treated with Okadaic Acid] results in decreased expression of GSTM2 mRNA; [Methylnitronitrosoguanidine co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of GSTM2 mRNA |
CTD |
PMID:19840844 |
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NCBI chr 2:210,778,041...210,782,807
Ensembl chr 2:210,720,704...210,782,856
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G |
Gsto1 |
glutathione S-transferase omega 1 |
multiple interactions |
ISO |
[Methylnitronitrosoguanidine co-treated with Cadmium Chloride] results in increased expression of GSTO1 mRNA; [Methylnitronitrosoguanidine co-treated with Okadaic Acid] results in increased expression of GSTO1 mRNA; [Methylnitronitrosoguanidine co-treated with Tetradecanoylphorbol Acetate] results in increased expression of GSTO1 mRNA |
CTD |
PMID:19840844 |
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NCBI chr 1:267,607,437...267,617,387
Ensembl chr 1:267,607,418...267,617,387
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G |
Gstp1 |
glutathione S-transferase pi 1 |
multiple interactions |
ISO |
[Methylnitronitrosoguanidine co-treated with Cadmium Chloride] results in increased expression of GSTP1 mRNA; [Methylnitronitrosoguanidine co-treated with Okadaic Acid] results in increased expression of GSTP1 mRNA; [Methylnitronitrosoguanidine co-treated with Tetradecanoylphorbol Acetate] results in increased expression of GSTP1 mRNA |
CTD |
PMID:19840844 |
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NCBI chr 1:219,291,679...219,294,147
Ensembl chr 1:219,291,679...219,294,147
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G |
Gtf2i |
general transcription factor II I |
multiple interactions |
ISO |
Methylnitronitrosoguanidine promotes the reaction [GTF2I protein binds to RRM2 promoter] |
CTD |
PMID:26921499 |
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NCBI chr12:25,410,804...25,487,970
Ensembl chr12:25,411,207...25,488,156
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G |
H2ax |
H2A.X variant histone |
increases expression multiple interactions |
ISO |
Methylnitronitrosoguanidine results in increased expression of H2AX protein modified form [[Methylnitronitrosoguanidine results in increased phosphorylation of and results in increased stability of and results in increased expression of E2F3 protein] which results in increased expression of RRM2 mRNA] inhibits the reaction [Methylnitronitrosoguanidine results in increased expression of H2AX protein modified form]; E2F3 protein inhibits the reaction [Methylnitronitrosoguanidine results in increased expression of H2AX protein modified form]; RRM2 protein inhibits the reaction [Methylnitronitrosoguanidine results in increased expression of H2AX protein modified form] |
CTD |
PMID:26921499 PMID:27233451 |
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NCBI chr 8:48,665,652...48,666,981
Ensembl chr 8:48,665,652...48,666,981
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G |
Hba-a2 |
hemoglobin alpha, adult chain 2 |
increases expression |
EXP |
Methylnitronitrosoguanidine results in increased expression of HBA1 mRNA |
CTD |
PMID:15120970 |
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NCBI chr10:15,589,364...15,590,207
Ensembl chr10:15,589,364...15,590,220
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G |
Hist2h4 |
histone cluster 2, H4 |
decreases expression |
ISO |
Methylnitronitrosoguanidine results in decreased expression of H4C2 mRNA |
CTD |
PMID:12634122 |
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NCBI chr 2:198,411,955...198,412,350
Ensembl chr 2:198,411,955...198,412,350
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G |
Hmgb1 |
high mobility group box 1 |
increases expression |
ISO |
Methylnitronitrosoguanidine results in increased expression of HMGB1 mRNA |
CTD |
PMID:12634122 |
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NCBI chr12:7,082,529...7,090,246
Ensembl chr16:37,500,017...37,502,237
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G |
Hmgb2 |
high mobility group box 2 |
decreases expression |
ISO |
Methylnitronitrosoguanidine results in decreased expression of HMGB2 mRNA |
CTD |
PMID:12634122 |
|
NCBI chr16:36,077,615...36,080,191
Ensembl chr16:36,077,617...36,080,191 Ensembl chr11:36,077,617...36,080,191
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G |
Hpgd |
15-hydroxyprostaglandin dehydrogenase |
decreases expression |
EXP |
Methylnitronitrosoguanidine results in decreased expression of HPGD mRNA |
CTD |
PMID:15120970 |
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NCBI chr16:37,457,134...37,495,758
Ensembl chr16:37,457,135...37,495,758
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G |
Hprt1 |
hypoxanthine phosphoribosyltransferase 1 |
multiple interactions |
ISO |
[Methylnitronitrosoguanidine co-treated with Cadmium Chloride] results in increased expression of HPRT mRNA; [Methylnitronitrosoguanidine co-treated with Okadaic Acid] results in increased expression of HPRT mRNA; [Methylnitronitrosoguanidine co-treated with Tetradecanoylphorbol Acetate] results in increased expression of HPRT mRNA |
CTD |
PMID:19840844 |
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NCBI chr X:158,196,640...158,228,815
Ensembl chr X:158,197,149...158,228,749
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G |
Hras |
HRas proto-oncogene, GTPase |
multiple interactions |
ISO |
Methylnitronitrosoguanidine inhibits the reaction [EGF protein results in increased activity of HRAS protein] |
CTD |
PMID:15708576 |
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NCBI chr 1:214,178,404...214,181,841
Ensembl chr 1:214,178,407...214,181,686
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G |
Hsp90aa1 |
heat shock protein 90 alpha family class A member 1 |
multiple interactions |
ISO |
[Methylnitronitrosoguanidine co-treated with Cadmium Chloride] results in increased expression of HSP90AA1 mRNA |
CTD |
PMID:19840844 |
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NCBI chr 6:135,107,262...135,112,793
Ensembl chr 6:135,107,271...135,112,775
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G |
Hsp90ab1 |
heat shock protein 90 alpha family class B member 1 |
multiple interactions |
ISO |
[Methylnitronitrosoguanidine co-treated with Cadmium Chloride] results in increased expression of HSP90AB1 mRNA |
CTD |
PMID:19840844 |
|
NCBI chr 9:17,817,791...17,823,163
Ensembl chr 9:17,817,721...17,823,243
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G |
Hsp90b1 |
heat shock protein 90 beta family member 1 |
increases expression |
ISO |
Methylnitronitrosoguanidine results in increased expression of HSP90B1 mRNA |
CTD |
PMID:12634122 |
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NCBI chr 7:27,226,570...27,240,533
Ensembl chr 7:27,226,569...27,240,533
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G |
Hspa1a |
heat shock protein family A (Hsp70) member 1A |
decreases expression |
EXP |
Methylnitronitrosoguanidine results in decreased expression of HSPA1A mRNA |
CTD |
PMID:15120970 |
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NCBI chr20:4,875,834...4,881,751
Ensembl chr20:4,877,324...4,879,779
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G |
Hspd1 |
heat shock protein family D (Hsp60) member 1 |
multiple interactions |
ISO |
[Methylnitronitrosoguanidine co-treated with Cadmium Chloride] results in increased expression of HSPD1 mRNA |
CTD |
PMID:19840844 |
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NCBI chr 9:61,680,529...61,691,202
Ensembl chr 9:61,680,530...61,690,956
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G |
Icam1 |
intercellular adhesion molecule 1 |
decreases response to substance multiple interactions increases expression |
ISO |
ICAM1 protein results in decreased susceptibility to Methylnitronitrosoguanidine prolinedithiocarbamate inhibits the reaction [Methylnitronitrosoguanidine results in increased expression of ICAM1 protein] Methylnitronitrosoguanidine results in increased expression of ICAM1 mRNA; Methylnitronitrosoguanidine results in increased expression of ICAM1 protein |
CTD |
PMID:22001597 |
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NCBI chr 8:22,035,287...22,047,049
Ensembl chr 8:22,035,256...22,047,059
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G |
Id1 |
inhibitor of DNA binding 1, HLH protein |
decreases expression |
ISO |
Methylnitronitrosoguanidine results in decreased expression of ID1 mRNA |
CTD |
PMID:12634122 |
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NCBI chr 3:148,214,623...148,216,715
Ensembl chr 3:148,215,540...148,216,718
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G |
Ier3 |
immediate early response 3 |
multiple interactions |
ISO |
[Methylnitronitrosoguanidine co-treated with Cadmium Chloride] results in decreased expression of IER3 mRNA; [Methylnitronitrosoguanidine co-treated with Okadaic Acid] results in decreased expression of IER3 mRNA; [Methylnitronitrosoguanidine co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of IER3 mRNA |
CTD |
PMID:19840844 |
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NCBI chr20:3,438,798...3,440,002
Ensembl chr20:3,438,798...3,440,769
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G |
Ifrd1 |
interferon-related developmental regulator 1 |
increases expression |
ISO |
Methylnitronitrosoguanidine results in increased expression of IFRD1 mRNA |
CTD |
PMID:12634122 |
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NCBI chr 6:60,132,025...60,151,354
Ensembl chr 6:60,132,024...60,151,420
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G |
Igkc |
immunoglobulin kappa constant |
increases expression |
EXP |
Methylnitronitrosoguanidine results in increased expression of IGKC mRNA |
CTD |
PMID:15120970 |
|
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G |
Igsf6 |
immunoglobulin superfamily, member 6 |
increases expression |
EXP |
Methylnitronitrosoguanidine results in increased expression of IGSF6 mRNA |
CTD |
PMID:15120970 |
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NCBI chr 1:190,997,029...191,007,503
Ensembl chr 1:190,997,029...191,007,503
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G |
Ikbkb |
inhibitor of nuclear factor kappa B kinase subunit beta |
multiple interactions increases expression |
EXP |
Eugenol inhibits the reaction [Methylnitronitrosoguanidine results in increased expression of IKBKB protein] |
CTD |
PMID:19851710 |
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NCBI chr16:74,177,233...74,230,809
Ensembl chr16:74,177,215...74,230,815
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G |
Irak1 |
interleukin-1 receptor-associated kinase 1 |
multiple interactions |
ISO |
[Methylnitronitrosoguanidine co-treated with Cadmium Chloride] results in decreased expression of IRAK1 mRNA; [Methylnitronitrosoguanidine co-treated with Okadaic Acid] results in decreased expression of IRAK1 mRNA; [Methylnitronitrosoguanidine co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of IRAK1 mRNA |
CTD |
PMID:19840844 |
|
NCBI chr X:156,716,469...156,726,367
Ensembl chr X:156,716,604...156,725,977
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G |
Itgb4 |
integrin subunit beta 4 |
decreases expression |
ISO |
Methylnitronitrosoguanidine results in decreased expression of ITGB4 mRNA |
CTD |
PMID:12634122 PMID:12773770 |
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NCBI chr10:104,524,000...104,560,180
Ensembl chr10:104,523,996...104,561,078
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G |
Jmjd6 |
jumonji domain containing 6, arginine demethylase and lysine hydroxylase |
multiple interactions |
ISO |
[Methylnitronitrosoguanidine co-treated with Cadmium Chloride] results in increased expression of JMJD6 mRNA |
CTD |
PMID:19840844 |
|
NCBI chr10:105,781,752...105,787,803
Ensembl chr10:105,781,753...105,787,803
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G |
Jpt1 |
Jupiter microtubule associated homolog 1 |
multiple interactions |
ISO |
[Methylnitronitrosoguanidine co-treated with Cadmium Chloride] results in increased expression of JPT1 mRNA |
CTD |
PMID:19840844 |
|
NCBI chr10:104,057,739...104,075,776
Ensembl chr10:104,057,697...104,075,777
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G |
Junb |
JunB proto-oncogene, AP-1 transcription factor subunit |
multiple interactions |
ISO |
Methylnitronitrosoguanidine promotes the reaction [[FOSL1 protein binds to JUNB protein] which binds to RRM2 promoter]; Methylnitronitrosoguanidine promotes the reaction [[FOSL1 protein binds to JUNB protein] which results in increased expression of RRM2 mRNA] |
CTD |
PMID:26921499 |
|
NCBI chr19:26,092,972...26,094,756
Ensembl chr19:26,092,974...26,094,756
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G |
Kctd12 |
potassium channel tetramerization domain containing 12 |
increases expression |
EXP |
Methylnitronitrosoguanidine results in increased expression of KCTD12 mRNA |
CTD |
PMID:15120970 |
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NCBI chr15:87,384,632...87,390,627
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G |
Kdm8 |
lysine demethylase 8 |
multiple interactions |
ISO |
Methylnitronitrosoguanidine inhibits the reaction [TP53 protein binds to KDM8 protein] |
CTD |
PMID:26025680 |
|
NCBI chr 1:196,838,460...196,854,192
Ensembl chr 1:196,839,321...196,854,180
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G |
Kit |
KIT proto-oncogene receptor tyrosine kinase |
increases expression |
ISO |
Methylnitronitrosoguanidine results in increased expression of KIT mRNA |
CTD |
PMID:12634122 |
|
NCBI chr14:35,072,131...35,149,638
Ensembl chr14:35,072,108...35,149,610
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G |
Kitlg |
KIT ligand |
decreases expression |
EXP |
Methylnitronitrosoguanidine results in decreased expression of KITLG mRNA |
CTD |
PMID:15120970 |
|
NCBI chr 7:42,269,784...42,351,054
Ensembl chr 7:42,269,784...42,351,054
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G |
Klf10 |
Kruppel-like factor 10 |
decreases expression |
EXP |
Methylnitronitrosoguanidine results in decreased expression of KLF10 mRNA |
CTD |
PMID:15120970 |
|
NCBI chr 7:77,156,010...77,162,096
Ensembl chr 7:77,156,006...77,162,148
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G |
Kras |
KRAS proto-oncogene, GTPase |
multiple interactions increases expression |
EXP |
geraniol inhibits the reaction [Methylnitronitrosoguanidine results in increased expression of KRAS mRNA] |
CTD |
PMID:28428697 |
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NCBI chr 4:179,482,562...179,515,483
Ensembl chr 4:179,486,105...179,515,558
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G |
Krt17 |
keratin 17 |
decreases expression |
ISO |
Methylnitronitrosoguanidine results in decreased expression of KRT17 mRNA |
CTD |
PMID:12634122 |
|
NCBI chr10:88,158,993...88,163,712
Ensembl chr10:88,118,001...88,163,723
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G |
Lgals3 |
galectin 3 |
multiple interactions |
ISO |
[Methylnitronitrosoguanidine co-treated with Tetradecanoylphorbol Acetate] results in increased expression of LGALS3 mRNA |
CTD |
PMID:19840844 |
|
NCBI chr15:24,153,602...24,165,537
Ensembl chr15:24,141,651...24,165,537
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G |
Lgals8 |
galectin 8 |
increases expression |
ISO |
Methylnitronitrosoguanidine results in increased expression of LGALS8 mRNA |
CTD |
PMID:12634122 |
|
NCBI chr17:66,487,451...66,515,316
Ensembl chr17:66,487,457...66,511,870
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G |
Lig1 |
DNA ligase 1 |
decreases expression |
ISO |
Methylnitronitrosoguanidine results in decreased expression of LIG1 mRNA |
CTD |
PMID:12634122 |
|
NCBI chr 1:75,356,212...75,394,757
Ensembl chr 1:75,356,220...75,394,758
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G |
Lipa |
lipase A, lysosomal acid type |
increases expression |
EXP |
Methylnitronitrosoguanidine results in increased expression of LIP1 mRNA |
CTD |
PMID:15120970 |
|
NCBI chr 1:252,816,536...252,959,348
Ensembl chr 1:252,816,527...252,849,904
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G |
Lox |
lysyl oxidase |
multiple interactions |
ISO |
[Methylnitronitrosoguanidine co-treated with Cadmium Chloride] results in decreased expression of LOX mRNA; [Methylnitronitrosoguanidine co-treated with Okadaic Acid] results in decreased expression of LOX mRNA; [Methylnitronitrosoguanidine co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of LOX mRNA |
CTD |
PMID:19840844 |
|
NCBI chr18:47,500,320...47,577,819
Ensembl chr18:47,500,330...47,577,819
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G |
Lpl |
lipoprotein lipase |
multiple interactions |
ISO |
[Methylnitronitrosoguanidine co-treated with Cadmium Chloride] results in decreased expression of LPL mRNA; [Methylnitronitrosoguanidine co-treated with Okadaic Acid] results in decreased expression of LPL mRNA; [Methylnitronitrosoguanidine co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of LPL mRNA |
CTD |
PMID:19840844 |
|
NCBI chr16:22,537,687...22,561,487
Ensembl chr16:22,537,056...22,561,496
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G |
Map2k1 |
mitogen activated protein kinase kinase 1 |
increases expression multiple interactions |
EXP |
Methylnitronitrosoguanidine results in increased expression of MAP2K1 mRNA geraniol inhibits the reaction [Methylnitronitrosoguanidine results in increased expression of MAP2K1 mRNA] |
CTD |
PMID:28428697 |
|
NCBI chr 8:69,134,218...69,722,573
Ensembl chr 8:69,134,223...69,164,758
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G |
Map3k12 |
mitogen activated protein kinase kinase kinase 12 |
multiple interactions |
ISO |
[Methylnitronitrosoguanidine co-treated with Cadmium Chloride] results in increased expression of MAP3K12 mRNA; [Methylnitronitrosoguanidine co-treated with Okadaic Acid] results in increased expression of MAP3K12 mRNA; [Methylnitronitrosoguanidine co-treated with Tetradecanoylphorbol Acetate] results in increased expression of MAP3K12 mRNA |
CTD |
PMID:19840844 |
|
NCBI chr 7:144,102,275...144,120,306
Ensembl chr 7:144,102,680...144,109,116
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G |
Mapk1 |
mitogen activated protein kinase 1 |
multiple interactions decreases phosphorylation |
ISO |
N-(oxo-5,6-dihydrophenanthridin-2-yl)-N,N-dimethylacetamide hydrochloride inhibits the reaction [Methylnitronitrosoguanidine results in decreased phosphorylation of MAPK1 protein]; U 0126 inhibits the reaction [N-(oxo-5,6-dihydrophenanthridin-2-yl)-N,N-dimethylacetamide hydrochloride inhibits the reaction [Methylnitronitrosoguanidine results in decreased phosphorylation of MAPK1 protein]] |
CTD |
PMID:17828454 |
|
NCBI chr11:88,203,863...88,273,301
Ensembl chr11:88,211,599...88,273,254
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G |
Mapk14 |
mitogen activated protein kinase 14 |
increases phosphorylation |
ISO |
Methylnitronitrosoguanidine results in increased phosphorylation of MAPK14 protein |
CTD |
PMID:22001597 |
|
NCBI chr20:5,933,290...5,995,137
Ensembl chr20:5,933,303...5,995,137
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G |
Mapk3 |
mitogen activated protein kinase 3 |
multiple interactions decreases phosphorylation |
ISO |
N-(oxo-5,6-dihydrophenanthridin-2-yl)-N,N-dimethylacetamide hydrochloride inhibits the reaction [Methylnitronitrosoguanidine results in decreased phosphorylation of MAPK3 protein]; U 0126 inhibits the reaction [N-(oxo-5,6-dihydrophenanthridin-2-yl)-N,N-dimethylacetamide hydrochloride inhibits the reaction [Methylnitronitrosoguanidine results in decreased phosphorylation of MAPK3 protein]] |
CTD |
PMID:17828454 |
|
NCBI chr 1:198,192,773...198,198,975
Ensembl chr 1:198,192,773...198,198,975
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G |
Mapk4 |
mitogen-activated protein kinase 4 |
increases expression |
ISO |
Methylnitronitrosoguanidine results in increased expression of MAPK4 mRNA |
CTD |
PMID:12634122 |
|
NCBI chr18:69,894,692...70,043,634
Ensembl chr18:69,894,684...69,944,632
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G |
Mapk8 |
mitogen-activated protein kinase 8 |
increases phosphorylation |
ISO |
Methylnitronitrosoguanidine results in increased phosphorylation of MAPK8 protein |
CTD |
PMID:22001597 |
|
NCBI chr16:9,620,854...9,709,342
Ensembl chr16:9,625,177...9,709,347
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G |
Mapk9 |
mitogen-activated protein kinase 9 |
increases expression |
ISO |
Methylnitronitrosoguanidine results in increased expression of MAPK9 mRNA |
CTD |
PMID:12634122 |
|
NCBI chr10:35,333,859...35,374,364
Ensembl chr10:35,333,859...35,374,355
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G |
Marcks |
myristoylated alanine rich protein kinase C substrate |
multiple interactions |
ISO |
[Methylnitronitrosoguanidine co-treated with Cadmium Chloride] results in decreased expression of MARCKS mRNA; [Methylnitronitrosoguanidine co-treated with Okadaic Acid] results in decreased expression of MARCKS mRNA; [Methylnitronitrosoguanidine co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of MARCKS mRNA |
CTD |
PMID:19840844 |
|
NCBI chr20:42,966,140...42,971,838
Ensembl chr20:42,966,140...42,971,838
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G |
Max |
MYC associated factor X |
increases expression |
ISO |
Methylnitronitrosoguanidine results in increased expression of MAX mRNA |
CTD |
PMID:12634122 |
|
NCBI chr 6:99,984,260...100,011,460
Ensembl chr 6:99,984,260...100,011,388
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G |
Mcam |
melanoma cell adhesion molecule |
increases expression |
ISO |
Methylnitronitrosoguanidine results in increased expression of MCAM mRNA |
CTD |
PMID:12634122 PMID:12773770 |
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NCBI chr 8:48,472,824...48,481,005
Ensembl chr 8:48,472,824...48,481,001
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G |
Mcm2 |
minichromosome maintenance complex component 2 |
decreases expression multiple interactions |
ISO |
Methylnitronitrosoguanidine results in decreased expression of MCM2 mRNA [Methylnitronitrosoguanidine co-treated with Cadmium Chloride] results in increased expression of MCM2 mRNA |
CTD |
PMID:12634122 PMID:19840844 |
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NCBI chr 4:120,825,699...120,840,221
Ensembl chr 4:120,825,699...120,840,111
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G |
Mcm4 |
minichromosome maintenance complex component 4 |
decreases expression |
ISO |
Methylnitronitrosoguanidine results in decreased expression of MCM4 mRNA |
CTD |
PMID:12634122 |
|
NCBI chr11:89,511,191...89,524,892
Ensembl chr11:89,511,191...89,524,892
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G |
Mcm6 |
minichromosome maintenance complex component 6 |
multiple interactions |
ISO |
[Methylnitronitrosoguanidine co-treated with Cadmium Chloride] results in increased expression of MCM6 mRNA |
CTD |
PMID:19840844 |
|
NCBI chr13:45,042,882...45,068,073
Ensembl chr13:45,042,882...45,068,077
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G |
Mdm2 |
MDM2 proto-oncogene |
increases expression multiple interactions |
ISO |
Methylnitronitrosoguanidine results in increased expression of MDM2 mRNA Cadmium Chloride promotes the reaction [Methylnitronitrosoguanidine results in increased expression of MDM2 protein] |
CTD |
PMID:12135628 PMID:12634122 |
|
NCBI chr 7:60,719,060...60,743,618
Ensembl chr 7:60,719,066...60,743,328
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G |
Mecom |
MDS1 and EVI1 complex locus |
increases expression |
ISO |
Methylnitronitrosoguanidine results in increased expression of MECOM mRNA |
CTD |
PMID:12634122 |
|
NCBI chr 2:117,396,084...117,993,604
Ensembl chr 2:117,396,007...117,454,769
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G |
Met |
MET proto-oncogene, receptor tyrosine kinase |
increases expression |
ISO |
Methylnitronitrosoguanidine results in increased expression of MET mRNA |
CTD |
PMID:12634122 |
|
NCBI chr 4:44,747,467...44,854,628
Ensembl chr 4:44,774,741...44,852,665
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G |
Mgmt |
O-6-methylguanine-DNA methyltransferase |
decreases response to substance |
ISO |
MGMT protein results in decreased susceptibility to Methylnitronitrosoguanidine |
CTD |
PMID:1727384 PMID:15010311 PMID:16043385 |
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NCBI chr 1:209,237,255...209,464,189
Ensembl chr 1:209,237,233...209,464,190
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G |
Mgst2 |
microsomal glutathione S-transferase 2 |
decreases expression |
ISO |
Methylnitronitrosoguanidine results in decreased expression of MGST2 mRNA |
CTD |
PMID:12634122 |
|
NCBI chr 2:140,708,396...140,727,381
Ensembl chr 2:140,708,397...140,727,281
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G |
Mgst3 |
microsomal glutathione S-transferase 3 |
multiple interactions |
ISO |
[Methylnitronitrosoguanidine co-treated with Okadaic Acid] results in increased expression of MGST3 mRNA |
CTD |
PMID:19840844 |
|
NCBI chr13:85,601,499...85,622,392
Ensembl chr13:85,601,499...85,622,314
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G |
Mir21 |
microRNA 21 |
increases expression |
ISO |
Methylnitronitrosoguanidine results in increased expression of MIR21 mRNA |
CTD |
PMID:24821435 |
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NCBI chr10:73,902,210...73,902,301
Ensembl chr10:73,902,210...73,902,301
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G |
Mlh1 |
mutL homolog 1 |
decreases expression |
ISO |
Methylnitronitrosoguanidine results in decreased expression of MLH1 protein |
CTD |
PMID:17671175 |
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NCBI chr 8:119,486,655...119,523,716
Ensembl chr 8:119,486,691...119,523,964
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G |
Mmp2 |
matrix metallopeptidase 2 |
multiple interactions increases expression |
EXP ISO |
Eugenol inhibits the reaction [Methylnitronitrosoguanidine results in increased expression of and results in increased activity of MMP2 protein]; Eugenol inhibits the reaction [Methylnitronitrosoguanidine results in increased expression of MMP2 mRNA]; Methylnitronitrosoguanidine results in increased expression of and results in increased activity of MMP2 protein [Methylnitronitrosoguanidine co-treated with Okadaic Acid] results in increased expression of MMP2 mRNA |
CTD |
PMID:19840844 PMID:20434464 |
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NCBI chr19:15,542,771...15,570,589
Ensembl chr19:15,542,765...15,570,611
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G |
Mmp9 |
matrix metallopeptidase 9 |
multiple interactions increases expression |
EXP |
Eugenol inhibits the reaction [Methylnitronitrosoguanidine results in increased expression of and results in increased activity of MMP9 protein]; Eugenol inhibits the reaction [Methylnitronitrosoguanidine results in increased expression of MMP9 mRNA]; Methylnitronitrosoguanidine results in increased expression of and results in increased activity of MMP9 protein |
CTD |
PMID:20434464 |
|
NCBI chr 3:161,413,410...161,421,473
Ensembl chr 3:161,413,298...161,421,520
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G |
Mpg |
N-methylpurine-DNA glycosylase |
increases response to substance |
ISO |
MPG protein results in increased susceptibility to Methylnitronitrosoguanidine |
CTD |
PMID:15299078 |
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NCBI chr10:15,661,768...15,667,995
Ensembl chr10:15,661,608...15,668,022
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G |
Mpp1 |
membrane palmitoylated protein 1 |
multiple interactions |
ISO |
[Methylnitronitrosoguanidine co-treated with Cadmium Chloride] results in decreased expression of MPP1 mRNA; [Methylnitronitrosoguanidine co-treated with Okadaic Acid] results in decreased expression of MPP1 mRNA; [Methylnitronitrosoguanidine co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of MPP1 mRNA |
CTD |
PMID:19840844 |
|
NCBI chr 1:148,450,213...148,458,945
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G |
Msh2 |
mutS homolog 2 |
increases expression |
ISO |
Methylnitronitrosoguanidine results in increased expression of MSH2 mRNA |
CTD |
PMID:12634122 |
|
NCBI chr 6:11,215,951...11,274,916
Ensembl chr 6:11,215,963...11,274,932
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G |
Mst1 |
macrophage stimulating 1 |
increases expression |
EXP |
Methylnitronitrosoguanidine results in increased expression of MST1 mRNA |
CTD |
PMID:15120970 |
|
NCBI chr 8:116,857,716...116,862,286
Ensembl chr 8:116,857,684...116,862,423
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G |
Mt1 |
metallothionein 1 |
multiple interactions |
ISO |
[Methylnitronitrosoguanidine co-treated with Cadmium Chloride] results in increased expression of MT1 mRNA; [Methylnitronitrosoguanidine co-treated with Okadaic Acid] results in increased expression of MT1 mRNA; [Methylnitronitrosoguanidine co-treated with Tetradecanoylphorbol Acetate] results in increased expression of MT1 mRNA |
CTD |
PMID:19840844 |
|
NCBI chr19:11,301,991...11,303,007
Ensembl chr17:78,793,336...78,793,724
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G |
Mutyh |
mutY DNA glycosylase |
multiple interactions |
ISO |
MUTYH protein promotes the reaction [Methylnitronitrosoguanidine results in increased expression of PARP1 protein] |
CTD |
PMID:26954031 |
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NCBI chr 5:135,663,328...135,675,348
Ensembl chr 5:135,663,371...135,675,344
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G |
Mybl1 |
MYB proto-oncogene like 1 |
increases expression |
ISO |
Methylnitronitrosoguanidine results in increased expression of MYBL1 mRNA |
CTD |
PMID:12634122 |
|
NCBI chr 5:9,279,756...9,315,112
Ensembl chr 5:9,279,970...9,315,114
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G |
Myc |
MYC proto-oncogene, bHLH transcription factor |
increases expression multiple interactions |
ISO |
Methylnitronitrosoguanidine results in increased expression of MYC protein Cadmium Chloride promotes the reaction [Methylnitronitrosoguanidine results in increased expression of MYC protein] |
CTD |
PMID:12135628 |
|
NCBI chr 7:102,586,313...102,591,240
Ensembl chr 7:102,586,313...102,591,240
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G |
Myl2 |
myosin light chain 2 |
increases expression |
ISO |
Methylnitronitrosoguanidine results in increased expression of MYL2 mRNA |
CTD |
PMID:12634122 |
|
NCBI chr12:39,951,863...39,959,065
Ensembl chr12:39,951,987...39,958,239
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G |
Myl9 |
myosin light chain 9 |
increases expression |
ISO |
Methylnitronitrosoguanidine results in increased expression of MYL9 mRNA |
CTD |
PMID:12634122 |
|
NCBI chr 3:152,857,573...152,863,961
Ensembl chr 3:152,857,592...152,863,960
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G |
Mylk |
myosin light chain kinase |
decreases expression |
ISO |
Methylnitronitrosoguanidine results in decreased expression of MYLK mRNA |
CTD |
PMID:12634122 |
|
NCBI chr11:69,013,060...69,260,039
Ensembl chr11:69,013,050...69,223,158
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G |
Nbl1 |
NBL1, DAN family BMP antagonist |
decreases expression |
ISO |
Methylnitronitrosoguanidine results in decreased expression of NBL1 mRNA |
CTD |
PMID:12634122 |
|
NCBI chr 5:157,524,569...157,535,701
Ensembl chr 5:157,524,513...157,535,664
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G |
Nfkb1 |
nuclear factor kappa B subunit 1 |
multiple interactions increases expression |
EXP |
Eugenol inhibits the reaction [Methylnitronitrosoguanidine results in increased expression of NFKB1 mRNA]; Eugenol inhibits the reaction [Methylnitronitrosoguanidine results in increased expression of NFKB1 protein] Methylnitronitrosoguanidine results in increased expression of NFKB1 mRNA; Methylnitronitrosoguanidine results in increased expression of NFKB1 protein |
CTD |
PMID:19851710 |
|
NCBI chr 2:240,773,520...240,890,053
Ensembl chr 2:240,773,456...240,866,689
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G |
Nfkbia |
NFKB inhibitor alpha |
multiple interactions increases expression decreases expression |
EXP ISO |
Eugenol inhibits the reaction [Methylnitronitrosoguanidine results in decreased expression of NFKBIA mRNA]; Eugenol inhibits the reaction [Methylnitronitrosoguanidine results in decreased expression of NFKBIA protein]; Eugenol inhibits the reaction [Methylnitronitrosoguanidine results in increased expression of NFKBIA protein modified form] Methylnitronitrosoguanidine results in increased phosphorylation of and results in increased degradation of NFKBIA protein Methylnitronitrosoguanidine results in decreased expression of NFKBIA mRNA; Methylnitronitrosoguanidine results in decreased expression of NFKBIA protein |
CTD |
PMID:19851710 PMID:22001597 |
|
NCBI chr 6:76,267,227...76,270,457
Ensembl chr 6:76,267,228...76,270,457
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G |
Nfya |
nuclear transcription factor Y subunit alpha |
multiple interactions |
ISO |
Methylnitronitrosoguanidine promotes the reaction [NFYA protein binds to RRM2 promoter]; Methylnitronitrosoguanidine promotes the reaction [NFYA protein results in increased expression of RRM2 mRNA] |
CTD |
PMID:26921499 |
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NCBI chr 9:14,551,752...14,577,002
Ensembl chr 9:14,551,758...14,576,967
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G |
Nfyb |
nuclear transcription factor Y subunit beta |
multiple interactions |
ISO |
Methylnitronitrosoguanidine promotes the reaction [NFYB protein binds to RRM2 promoter]; Methylnitronitrosoguanidine promotes the reaction [NFYB protein results in increased expression of RRM2 mRNA]; NFYB protein promotes the reaction [Methylnitronitrosoguanidine promotes the reaction [E2F3 protein binds to RRM2 promoter]]; NFYB protein promotes the reaction [Methylnitronitrosoguanidine promotes the reaction [E2F3 protein results in increased expression of RRM2 mRNA]]; NFYB protein promotes the reaction [Methylnitronitrosoguanidine results in increased expression of RRM2 mRNA]; NFYB protein promotes the reaction [Methylnitronitrosoguanidine results in increased expression of RRM2 protein] |
CTD |
PMID:26921499 |
|
NCBI chr 7:27,081,667...27,097,481
Ensembl chr 7:27,081,667...27,097,479
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G |
Nfyc |
nuclear transcription factor Y subunit gamma |
multiple interactions |
ISO |
Methylnitronitrosoguanidine promotes the reaction [NFYC protein binds to RRM2 promoter]; Methylnitronitrosoguanidine promotes the reaction [NFYC protein results in increased expression of RRM2 mRNA] |
CTD |
PMID:26921499 |
|
NCBI chr 5:139,687,442...139,760,154
Ensembl chr 5:139,687,448...139,749,050
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G |
Nrp1 |
neuropilin 1 |
increases expression |
EXP |
Methylnitronitrosoguanidine results in increased expression of NRP1 mRNA |
CTD |
PMID:15120970 |
|
NCBI chr19:61,332,351...61,486,166
Ensembl chr19:61,332,351...61,485,858
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G |
Odc1 |
ornithine decarboxylase 1 |
multiple interactions |
ISO |
[Methylnitronitrosoguanidine co-treated with Cadmium Chloride] results in increased expression of ODC1 mRNA |
CTD |
PMID:19840844 |
|
NCBI chr 6:42,852,529...42,859,142
Ensembl chr 6:42,852,683...42,859,927
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G |
Pa2g4 |
proliferation-associated 2G4 |
multiple interactions |
ISO |
[Methylnitronitrosoguanidine co-treated with Cadmium Chloride] results in increased expression of PA2G4 mRNA |
CTD |
PMID:19840844 |
|
NCBI chr 7:2,979,587...2,987,055
Ensembl chr 7:2,979,588...2,987,055
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G |
Parg |
poly (ADP-ribose) glycohydrolase |
multiple interactions affects response to substance |
ISO |
[Hydrolyzable Tannins results in decreased activity of PARG protein] which results in decreased susceptibility to Methylnitronitrosoguanidine; [nobotanin B results in decreased activity of PARG protein] which results in decreased susceptibility to Methylnitronitrosoguanidine; benzamide inhibits the reaction [PARG affects the susceptibility to Methylnitronitrosoguanidine] |
CTD |
PMID:11593040 PMID:15591342 |
|
NCBI chr16:8,350,168...8,457,999
Ensembl chr16:8,350,326...8,457,996
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G |
Parp1 |
poly (ADP-ribose) polymerase 1 |
multiple interactions increases expression increases response to substance affects cleavage increases activity |
ISO |
[benzamide results in decreased activity of PARP1 protein] which results in decreased susceptibility to Methylnitronitrosoguanidine; [Methylnitronitrosoguanidine results in increased activity of PARP1 protein] which results in decreased abundance of NAD; benzamide inhibits the reaction [[Methylnitronitrosoguanidine results in increased activity of PARP1 protein] which results in decreased abundance of NAD]; Eugenol affects the reaction [Methylnitronitrosoguanidine affects the cleavage of PARP1 protein]; Hydrolyzable Tannins inhibits the reaction [[Methylnitronitrosoguanidine results in increased activity of PARP1 protein] which results in decreased abundance of NAD]; MUTYH protein promotes the reaction [Methylnitronitrosoguanidine results in increased expression of PARP1 protein] PARP1 protein results in increased susceptibility to Methylnitronitrosoguanidine |
CTD |
PMID:11593040 PMID:20434464 PMID:22001597 PMID:26954031 |
|
NCBI chr13:98,857,255...98,889,444
Ensembl chr13:98,857,177...98,889,716
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G |
Pcbp2 |
poly(rC) binding protein 2 |
multiple interactions |
ISO |
[Methylnitronitrosoguanidine co-treated with Cadmium Chloride] results in increased expression of PCBP2 mRNA; [Methylnitronitrosoguanidine co-treated with Okadaic Acid] results in increased expression of PCBP2 mRNA; [Methylnitronitrosoguanidine co-treated with Tetradecanoylphorbol Acetate] results in increased expression of PCBP2 mRNA |
CTD |
PMID:19840844 |
|
NCBI chr 7:144,077,901...144,103,723
Ensembl chr 7:144,078,496...144,101,893
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G |
Pcdh7 |
protocadherin 7 |
decreases expression |
ISO |
Methylnitronitrosoguanidine results in decreased expression of PCDH7 mRNA |
CTD |
PMID:12634122 |
|
NCBI chr14:54,649,054...55,081,632
Ensembl chr14:55,072,200...55,081,551
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G |
Pcna |
proliferating cell nuclear antigen |
decreases expression increases expression multiple interactions |
ISO EXP |
Methylnitronitrosoguanidine results in decreased expression of PCNA mRNA Methylnitronitrosoguanidine results in increased expression of PCNA mRNA; Methylnitronitrosoguanidine results in increased expression of PCNA protein [Methylnitronitrosoguanidine co-treated with Cadmium Chloride] results in increased expression of PCNA mRNA; [Methylnitronitrosoguanidine co-treated with Okadaic Acid] results in increased expression of PCNA mRNA; [Methylnitronitrosoguanidine co-treated with Tetradecanoylphorbol Acetate] results in increased expression of PCNA mRNA; Cadmium Chloride inhibits the reaction [Methylnitronitrosoguanidine results in decreased expression of PCNA mRNA]; Cadmium Chloride promotes the reaction [Methylnitronitrosoguanidine results in increased expression of PCNA protein] Eugenol inhibits the reaction [Methylnitronitrosoguanidine results in increased expression of PCNA mRNA]; Eugenol inhibits the reaction [Methylnitronitrosoguanidine results in increased expression of PCNA protein]; geraniol inhibits the reaction [Methylnitronitrosoguanidine results in increased expression of PCNA protein] |
CTD |
PMID:11516527 PMID:12135628 PMID:12634122 PMID:19840844 PMID:19851710 PMID:22330348 PMID:28428697 |
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NCBI chr 3:124,880,698...124,884,570
Ensembl chr 3:124,880,698...124,884,570
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|
G |
Pdgfb |
platelet derived growth factor subunit B |
increases expression |
ISO |
Methylnitronitrosoguanidine results in increased expression of PDGFB mRNA |
CTD |
PMID:12634122 |
|
NCBI chr 7:121,215,458...121,233,092
Ensembl chr 7:121,214,628...121,232,741
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G |
Pdgfra |
platelet derived growth factor receptor alpha |
multiple interactions |
ISO |
[Methylnitronitrosoguanidine co-treated with Cadmium Chloride] results in decreased expression of PDGFRA mRNA; [Methylnitronitrosoguanidine co-treated with Okadaic Acid] results in decreased expression of PDGFRA mRNA; [Methylnitronitrosoguanidine co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of PDGFRA mRNA |
CTD |
PMID:19840844 |
|
NCBI chr14:35,527,926...35,581,130
Ensembl chr14:35,527,927...35,581,031
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G |
Pdia3 |
protein disulfide isomerase family A, member 3 |
multiple interactions |
ISO |
[Methylnitronitrosoguanidine co-treated with Cadmium Chloride] results in increased expression of PDIA3 mRNA; [Methylnitronitrosoguanidine co-treated with Okadaic Acid] results in increased expression of PDIA3 mRNA; [Methylnitronitrosoguanidine co-treated with Tetradecanoylphorbol Acetate] results in increased expression of PDIA3 mRNA |
CTD |
PMID:19840844 |
|
NCBI chr 3:113,376,983...113,400,707
Ensembl chr 3:113,376,983...113,400,707
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G |
Pea15 |
proliferation and apoptosis adaptor protein 15 |
increases expression |
ISO |
Methylnitronitrosoguanidine results in increased expression of PEA15 mRNA |
CTD |
PMID:12634122 |
|
NCBI chr13:90,579,844...90,589,466
Ensembl chr13:90,579,846...90,589,466
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G |
Pgk1 |
phosphoglycerate kinase 1 |
increases expression |
ISO |
Methylnitronitrosoguanidine results in increased expression of PGK1 mRNA |
CTD |
PMID:12634122 |
|
NCBI chr X:77,263,399...77,279,373
Ensembl chr X:77,263,359...77,279,367
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G |
Pgr |
progesterone receptor |
decreases expression multiple interactions |
EXP |
Methylnitronitrosoguanidine results in decreased expression of PGR protein geraniol inhibits the reaction [Methylnitronitrosoguanidine results in decreased expression of PGR protein] |
CTD |
PMID:28428697 |
|
NCBI chr 8:7,128,656...7,187,796
Ensembl chr 8:7,128,656...7,187,796
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G |
Pik3r1 |
phosphoinositide-3-kinase regulatory subunit 1 |
increases expression multiple interactions |
EXP |
Methylnitronitrosoguanidine results in increased expression of PIK3R1 mRNA geraniol inhibits the reaction [Methylnitronitrosoguanidine results in increased expression of PIK3R1 mRNA] |
CTD |
PMID:28428697 |
|
NCBI chr 2:31,742,326...31,826,882
Ensembl chr 2:31,745,088...31,826,867
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G |
Plxna3 |
plexin A3 |
increases expression |
ISO |
Methylnitronitrosoguanidine results in increased expression of PLXNA3 mRNA |
CTD |
PMID:12634122 |
|
NCBI chr X:156,363,400...156,379,433
Ensembl chr X:156,363,405...156,379,189
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G |
Podxl |
podocalyxin-like |
multiple interactions |
ISO |
[Methylnitronitrosoguanidine co-treated with Cadmium Chloride] results in decreased expression of PODXL mRNA; [Methylnitronitrosoguanidine co-treated with Okadaic Acid] results in decreased expression of PODXL mRNA |
CTD |
PMID:19840844 |
|
NCBI chr 4:58,829,049...58,893,353
Ensembl chr 4:58,829,060...58,893,170
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G |
Postn |
periostin |
decreases expression |
EXP |
Methylnitronitrosoguanidine results in decreased expression of POSTN mRNA |
CTD |
PMID:15120970 |
|
NCBI chr 2:143,656,820...143,688,087
Ensembl chr 2:143,656,793...143,688,087
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G |
Ppp2r2a |
protein phosphatase 2, regulatory subunit B, alpha |
decreases response to substance |
ISO |
PPP2R2A protein results in decreased susceptibility to Methylnitronitrosoguanidine |
CTD |
PMID:25772433 |
|
NCBI chr15:43,673,958...43,733,182
Ensembl chr15:43,673,960...43,733,182
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G |
Ppp2r5c |
protein phosphatase 2, regulatory subunit B', gamma |
increases response to substance |
ISO |
PPP2R5C protein results in increased susceptibility to Methylnitronitrosoguanidine |
CTD |
PMID:25772433 |
|
NCBI chr 6:134,804,128...134,941,912
Ensembl chr 6:134,804,141...134,939,358
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G |
Ppp2r5e |
protein phosphatase 2 regulatory subunit B', epsilon |
decreases response to substance |
ISO |
PPP2R5E protein results in decreased susceptibility to Methylnitronitrosoguanidine |
CTD |
PMID:25772433 |
|
NCBI chr 6:98,417,974...98,567,016
Ensembl chr 6:98,417,974...98,566,966
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G |
Prkd1 |
protein kinase D1 |
increases expression |
ISO |
Methylnitronitrosoguanidine results in increased expression of PRKD1 mRNA |
CTD |
PMID:12634122 |
|
NCBI chr 6:71,035,017...71,349,531
Ensembl chr 6:71,035,332...71,349,249
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G |
Pten |
phosphatase and tensin homolog |
decreases response to substance multiple interactions decreases expression |
ISO EXP |
PTEN protein results in decreased susceptibility to Methylnitronitrosoguanidine geraniol inhibits the reaction [Methylnitronitrosoguanidine results in decreased expression of PTEN protein] |
CTD |
PMID:20530668 PMID:28428697 |
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NCBI chr 1:251,421,814...251,487,634
Ensembl chr 1:251,421,596...251,487,832
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G |
Ptn |
pleiotrophin |
multiple interactions |
ISO |
[Methylnitronitrosoguanidine co-treated with Cadmium Chloride] results in decreased expression of PTN mRNA; [Methylnitronitrosoguanidine co-treated with Okadaic Acid] results in decreased expression of PTN mRNA; [Methylnitronitrosoguanidine co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of PTN mRNA |
CTD |
PMID:19840844 |
|
NCBI chr 4:64,239,156...64,330,996
Ensembl chr 4:64,239,158...64,330,996
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G |
Ptp4a1 |
protein tyrosine phosphatase 4A1 |
increases expression |
ISO |
Methylnitronitrosoguanidine results in increased expression of PTP4A1 mRNA |
CTD |
PMID:12634122 |
|
NCBI chr 9:37,223,363...37,254,222
Ensembl chr 9:37,223,729...37,231,291
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G |
Ptpra |
protein tyrosine phosphatase, receptor type, A |
decreases expression |
ISO |
Methylnitronitrosoguanidine results in decreased expression of PTPRA mRNA |
CTD |
PMID:12634122 |
|
NCBI chr 3:122,976,066...123,084,585
Ensembl chr 3:122,976,104...123,084,863
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G |
Ptprg |
protein tyrosine phosphatase, receptor type, G |
decreases expression |
ISO |
Methylnitronitrosoguanidine results in decreased expression of PTPRG mRNA |
CTD |
PMID:12634122 |
|
NCBI chr15:12,926,056...13,633,839
Ensembl chr15:12,926,167...13,228,607
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G |
Ptprs |
protein tyrosine phosphatase, receptor type, S |
decreases expression |
ISO |
Methylnitronitrosoguanidine results in decreased expression of PTPRS mRNA |
CTD |
PMID:12634122 |
|
NCBI chr 9:10,585,360...10,646,205
Ensembl chr 9:10,603,813...10,645,939
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G |
Pttg1 |
PTTG1 regulator of sister chromatid separation, securin |
multiple interactions |
ISO |
[Methylnitronitrosoguanidine co-treated with Cadmium Chloride] results in increased expression of PTTG1 mRNA; [Methylnitronitrosoguanidine co-treated with Okadaic Acid] results in increased expression of PTTG1 mRNA; [Methylnitronitrosoguanidine co-treated with Tetradecanoylphorbol Acetate] results in increased expression of PTTG1 mRNA |
CTD |
PMID:19840844 |
|
NCBI chr10:29,014,332...29,026,088
Ensembl chr10:29,020,049...29,026,002
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G |
Pura |
purine rich element binding protein A |
multiple interactions |
ISO |
Methylnitronitrosoguanidine promotes the reaction [PURA protein binds to RRM2 promoter]; Methylnitronitrosoguanidine promotes the reaction [PURA protein results in increased expression of RRM2 mRNA] |
CTD |
PMID:26921499 |
|
NCBI chr18:29,104,712...29,114,918
Ensembl chr18:29,110,242...29,111,156
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G |
Racgap1 |
Rac GTPase-activating protein 1 |
multiple interactions |
ISO |
[Methylnitronitrosoguanidine co-treated with Okadaic Acid] results in increased expression of RACGAP1 mRNA |
CTD |
PMID:19840844 |
|
NCBI chr 7:141,277,303...141,308,849
Ensembl chr 7:141,277,312...141,307,233
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G |
Rad21 |
RAD21 cohesin complex component |
multiple interactions |
ISO |
[Methylnitronitrosoguanidine co-treated with Okadaic Acid] results in increased expression of RAD21 mRNA |
CTD |
PMID:19840844 |
|
NCBI chr 7:91,511,755...91,538,673
Ensembl chr 7:91,511,756...91,538,673
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G |
Rad23a |
RAD23 homolog A, nucleotide excision repair protein |
decreases expression |
ISO |
Methylnitronitrosoguanidine results in decreased expression of RAD23A mRNA |
CTD |
PMID:12634122 PMID:12773770 |
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NCBI chr19:25,949,488...25,956,677
Ensembl chr19:25,949,490...25,955,391
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G |
Rbbp5 |
RB binding protein 5, histone lysine methyltransferase complex subunit |
increases expression |
ISO |
Methylnitronitrosoguanidine results in increased expression of RBBP5 mRNA |
CTD |
PMID:12634122 |
|
NCBI chr13:49,250,301...49,277,152
Ensembl chr13:49,250,301...49,277,152
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G |
Rbm6 |
RNA binding motif protein 6 |
increases expression |
ISO |
Methylnitronitrosoguanidine results in increased expression of RBM6 mRNA |
CTD |
PMID:12634122 |
|
NCBI chr 8:116,535,403...116,635,851
Ensembl chr 8:116,535,403...116,635,851
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G |
Reck |
reversion-inducing-cysteine-rich protein with kazal motifs |
multiple interactions decreases expression |
EXP |
Eugenol inhibits the reaction [Methylnitronitrosoguanidine results in decreased expression of RECK mRNA]; Eugenol inhibits the reaction [Methylnitronitrosoguanidine results in decreased expression of RECK protein] Methylnitronitrosoguanidine results in decreased expression of RECK mRNA; Methylnitronitrosoguanidine results in decreased expression of RECK protein |
CTD |
PMID:20434464 |
|
NCBI chr 5:59,348,568...59,415,169
Ensembl chr 5:59,348,639...59,415,135
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G |
Rela |
RELA proto-oncogene, NF-kB subunit |
multiple interactions increases expression |
EXP |
Eugenol inhibits the reaction [Methylnitronitrosoguanidine results in increased expression of RELA mRNA]; Eugenol inhibits the reaction [Methylnitronitrosoguanidine results in increased expression of RELA protein] Methylnitronitrosoguanidine results in increased expression of RELA mRNA; Methylnitronitrosoguanidine results in increased expression of RELA protein |
CTD |
PMID:19851710 |
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NCBI chr 1:220,992,770...221,003,249
Ensembl chr 1:220,992,770...221,003,249
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G |
Reln |
reelin |
increases expression |
EXP |
Methylnitronitrosoguanidine results in increased expression of RELN mRNA |
CTD |
PMID:15120970 |
|
NCBI chr 4:9,347,533...9,774,257
Ensembl chr 4:9,347,528...9,773,670
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G |
Rgs18 |
regulator of G-protein signaling 18 |
increases expression |
EXP |
Methylnitronitrosoguanidine results in increased expression of RGS18 mRNA |
CTD |
PMID:15120970 |
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NCBI chr13:61,564,381...61,591,139
Ensembl chr13:61,565,483...61,591,139
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G |
Ros1 |
ROS proto-oncogene 1 , receptor tyrosine kinase |
increases expression |
EXP |
Methylnitronitrosoguanidine results in increased expression of ROS1 mRNA |
CTD |
PMID:15120970 |
|
NCBI chr20:33,100,190...33,323,544
Ensembl chr20:33,100,191...33,323,367
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G |
Rpl7 |
ribosomal protein L7 |
multiple interactions |
ISO |
[Methylnitronitrosoguanidine co-treated with Cadmium Chloride] results in increased expression of RPL7 mRNA; [Methylnitronitrosoguanidine co-treated with Okadaic Acid] results in increased expression of RPL7 mRNA; [Methylnitronitrosoguanidine co-treated with Tetradecanoylphorbol Acetate] results in increased expression of RPL7 mRNA |
CTD |
PMID:19840844 |
|
NCBI chr 5:2,633,517...2,636,525
Ensembl chr 5:2,632,712...2,640,021
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G |
Rps11 |
ribosomal protein S11 |
multiple interactions |
ISO |
[Methylnitronitrosoguanidine co-treated with Tetradecanoylphorbol Acetate] results in increased expression of RPS11 mRNA |
CTD |
PMID:19840844 |
|
NCBI chr 1:101,116,641...101,118,749
Ensembl chr 1:101,116,635...101,118,825
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G |
Rps20 |
ribosomal protein S20 |
multiple interactions |
ISO |
[Methylnitronitrosoguanidine co-treated with Cadmium Chloride] results in increased expression of RPS20 mRNA; [Methylnitronitrosoguanidine co-treated with Okadaic Acid] results in increased expression of RPS20 mRNA; [Methylnitronitrosoguanidine co-treated with Tetradecanoylphorbol Acetate] results in increased expression of RPS20 mRNA |
CTD |
PMID:19840844 |
|
NCBI chr 5:16,706,052...16,707,214
Ensembl chr 5:16,706,082...16,706,909
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G |
Rpsa |
ribosomal protein SA |
increases expression |
ISO |
Methylnitronitrosoguanidine results in increased expression of RPSA mRNA |
CTD |
PMID:12773770 |
|
NCBI chr 8:128,806,053...128,809,987
Ensembl chr 8:128,806,129...128,809,986
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G |
Rrm2 |
ribonucleotide reductase regulatory subunit M2 |
increases expression multiple interactions |
ISO |
Methylnitronitrosoguanidine results in increased expression of RRM2 mRNA [[Methylnitronitrosoguanidine results in increased phosphorylation of and results in increased stability of and results in increased expression of E2F3 protein] which results in increased expression of RRM2 mRNA] inhibits the reaction [Methylnitronitrosoguanidine results in increased expression of H2AX protein modified form]; [Methylnitronitrosoguanidine results in increased phosphorylation of and results in increased stability of and results in increased expression of E2F3 protein] which results in increased expression of RRM2 mRNA; ATR protein promotes the reaction [Methylnitronitrosoguanidine results in increased expression of RRM2 mRNA]; ATR protein promotes the reaction [Methylnitronitrosoguanidine results in increased expression of RRM2 protein]; CHEK1 protein promotes the reaction [Methylnitronitrosoguanidine results in increased expression of RRM2 mRNA]; CHEK1 protein promotes the reaction [Methylnitronitrosoguanidine results in increased expression of RRM2 protein]; CHIR-124 inhibits the reaction [Methylnitronitrosoguanidine results in increased expression of RRM2 protein]; E2F3 protein promotes the reaction [Methylnitronitrosoguanidine results in increased expression of RRM2 mRNA]; E2F3 protein promotes the reaction [Methylnitronitrosoguanidine results in increased expression of RRM2 protein]; Methylnitronitrosoguanidine promotes the reaction [[FOSL1 protein binds to JUNB protein] which binds to RRM2 promoter]; Methylnitronitrosoguanidine promotes the reaction [[FOSL1 protein binds to JUNB protein] which results in increased expression of RRM2 mRNA]; Methylnitronitrosoguanidine promotes the reaction [DP1 protein binds to RRM2 promoter]; Methylnitronitrosoguanidine promotes the reaction [DP1 protein results in increased expression of RRM2 mRNA]; Methylnitronitrosoguanidine promotes the reaction [E2F1 protein binds to RRM2 promoter]; Methylnitronitrosoguanidine promotes the reaction [E2F1 protein results in increased expression of RRM2 mRNA]; Methylnitronitrosoguanidine promotes the reaction [E2F3 protein binds to RRM2 promoter]; Methylnitronitrosoguanidine promotes the reaction [E2F3 protein results in increased expression of RRM2 mRNA]; Methylnitronitrosoguanidine promotes the reaction [FOSL1 protein binds to RRM2 promoter]; Methylnitronitrosoguanidine promotes the reaction [FOSL1 protein results in increased expression of RRM2 mRNA]; Methylnitronitrosoguanidine promotes the reaction [GTF2I protein binds to RRM2 promoter]; Methylnitronitrosoguanidine promotes the reaction [IFI16 protein binds to RRM2 promoter]; Methylnitronitrosoguanidine promotes the reaction [IFI16 protein results in increased expression of RRM2 mRNA]; Methylnitronitrosoguanidine promotes the reaction [NFYA protein binds to RRM2 promoter]; Methylnitronitrosoguanidine promotes the reaction [NFYA protein results in increased expression of RRM2 mRNA]; Methylnitronitrosoguanidine promotes the reaction [NFYB protein binds to RRM2 promoter]; Methylnitronitrosoguanidine promotes the reaction [NFYB protein results in increased expression of RRM2 mRNA]; Methylnitronitrosoguanidine promotes the reaction [NFYC protein binds to RRM2 promoter]; Methylnitronitrosoguanidine promotes the reaction [NFYC protein results in increased expression of RRM2 mRNA]; Methylnitronitrosoguanidine promotes the reaction [PURA protein binds to RRM2 promoter]; Methylnitronitrosoguanidine promotes the reaction [PURA protein results in increased expression of RRM2 mRNA]; Methylnitronitrosoguanidine promotes the reaction [RUVBL1 protein binds to RRM2 promoter]; Methylnitronitrosoguanidine promotes the reaction [RUVBL1 protein results in increased expression of RRM2 mRNA]; Methylnitronitrosoguanidine promotes the reaction [YY1 protein binds to RRM2 promoter]; Methylnitronitrosoguanidine promotes the reaction [YY1 protein results in increased expression of RRM2 mRNA]; Methylnitronitrosoguanidine results in increased expression of and affects the localization of RRM2 protein; NFYB protein promotes the reaction [Methylnitronitrosoguanidine promotes the reaction [E2F3 protein binds to RRM2 promoter]]; NFYB protein promotes the reaction [Methylnitronitrosoguanidine promotes the reaction [E2F3 protein results in increased expression of RRM2 mRNA]]; NFYB protein promotes the reaction [Methylnitronitrosoguanidine results in increased expression of RRM2 mRNA]; NFYB protein promotes the reaction [Methylnitronitrosoguanidine results in increased expression of RRM2 protein]; RRM2 protein inhibits the reaction [Methylnitronitrosoguanidine results in increased expression of H2AX protein modified form] |
CTD |
PMID:26921499 |
|
NCBI chr 6:43,884,627...43,890,818
Ensembl chr 6:43,884,678...43,889,515
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G |
Rrm2b |
ribonucleotide reductase regulatory TP53 inducible subunit M2B |
increases expression multiple interactions affects expression |
ISO |
Methylnitronitrosoguanidine results in increased expression of RRM2B mRNA ATR protein promotes the reaction [Methylnitronitrosoguanidine results in increased expression of RRM2B protein]; CHEK2 protein promotes the reaction [Methylnitronitrosoguanidine results in increased expression of RRM2B protein]; E2F1 protein promotes the reaction [Methylnitronitrosoguanidine results in increased expression of RRM2B mRNA]; E2F3 protein promotes the reaction [Methylnitronitrosoguanidine results in increased expression of RRM2B mRNA]; Methylnitronitrosoguanidine results in increased expression of and affects the localization of RRM2B protein; TP53 protein mutant form inhibits the reaction [Methylnitronitrosoguanidine results in increased expression of RRM2B protein] Methylnitronitrosoguanidine affects the expression of RRM2B mRNA |
CTD |
PMID:21704725 PMID:26921499 |
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NCBI chr 7:76,750,045...76,780,817
Ensembl chr 7:76,750,050...76,780,817
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G |
RT1-Db1 |
RT1 class II, locus Db1 |
increases expression |
ISO |
Methylnitronitrosoguanidine results in increased expression of HLA-DRB1 mRNA |
CTD |
PMID:12634122 |
|
NCBI chr20:4,087,621...4,097,190
Ensembl chr20:4,087,618...4,097,190
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G |
Ruvbl1 |
RuvB-like AAA ATPase 1 |
multiple interactions |
ISO |
Methylnitronitrosoguanidine promotes the reaction [RUVBL1 protein binds to RRM2 promoter]; Methylnitronitrosoguanidine promotes the reaction [RUVBL1 protein results in increased expression of RRM2 mRNA] |
CTD |
PMID:26921499 |
|
NCBI chr 4:120,411,917...120,447,458
Ensembl chr 4:120,411,991...120,447,455
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G |
Sec61g |
SEC61 translocon subunit gamma |
multiple interactions |
ISO |
[Methylnitronitrosoguanidine co-treated with Tetradecanoylphorbol Acetate] results in increased expression of SEC61G mRNA |
CTD |
PMID:19840844 |
|
NCBI chr14:99,774,589...99,780,964
Ensembl chr14:99,774,589...99,780,964
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G |
Selenop |
selenoprotein P |
multiple interactions |
ISO |
[Methylnitronitrosoguanidine co-treated with Cadmium Chloride] results in decreased expression of SELENOP mRNA; [Methylnitronitrosoguanidine co-treated with Okadaic Acid] results in decreased expression of SELENOP mRNA; [Methylnitronitrosoguanidine co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of SELENOP mRNA |
CTD |
PMID:19840844 |
|
NCBI chr 2:53,105,912...53,116,198
Ensembl chr 2:53,109,684...53,114,858
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G |
Serpine1 |
serpin family E member 1 |
increases expression |
EXP |
Methylnitronitrosoguanidine results in increased expression of SERPINE1 mRNA |
CTD |
PMID:15120970 |
|
NCBI chr12:22,641,104...22,651,482
Ensembl chr12:22,641,104...22,651,482
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G |
Serping1 |
serpin family G member 1 |
increases expression |
ISO |
Methylnitronitrosoguanidine results in increased expression of SERPING1 mRNA |
CTD |
PMID:12634122 |
|
NCBI chr 3:72,161,230...72,171,109
Ensembl chr 3:72,161,189...72,171,078
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G |
Smad2 |
SMAD family member 2 |
decreases expression |
ISO |
Methylnitronitrosoguanidine results in decreased expression of SMAD2 mRNA |
CTD |
PMID:12634122 |
|
NCBI chr18:72,550,107...72,612,078
Ensembl chr18:72,550,219...72,612,078
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G |
Snrpn |
small nuclear ribonucleoprotein polypeptide N |
increases expression |
ISO |
Methylnitronitrosoguanidine results in increased expression of SNRPN mRNA |
CTD |
PMID:12634122 |
|
NCBI chr 1:195,074,328...195,096,460
Ensembl chr 1:195,074,330...195,096,460
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G |
Sparc |
secreted protein acidic and cysteine rich |
decreases expression |
ISO |
Methylnitronitrosoguanidine results in decreased expression of SPARC mRNA |
CTD |
PMID:12634122 |
|
NCBI chr10:40,742,390...40,764,232
Ensembl chr10:40,742,400...40,764,185
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G |
Spink1 |
serine peptidase inhibitor, Kazal type 1 |
increases expression |
ISO |
Methylnitronitrosoguanidine results in increased expression of SPINK1 mRNA |
CTD |
PMID:12634122 |
|
NCBI chr18:38,221,919...38,242,092
Ensembl chr18:38,221,681...38,242,119
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G |
Spint2 |
serine peptidase inhibitor, Kunitz type, 2 |
decreases expression increases expression |
ISO |
Methylnitronitrosoguanidine results in decreased expression of SPINT2 mRNA Methylnitronitrosoguanidine results in increased expression of SPINT2 mRNA |
CTD |
PMID:12634122 |
|
NCBI chr 1:87,199,373...87,221,826
Ensembl chr 1:87,199,313...87,221,892
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G |
Spp1 |
secreted phosphoprotein 1 |
multiple interactions |
ISO |
[Methylnitronitrosoguanidine co-treated with Cadmium Chloride] results in increased expression of SPP1 mRNA; [Methylnitronitrosoguanidine co-treated with Okadaic Acid] results in increased expression of SPP1 mRNA; [Methylnitronitrosoguanidine co-treated with Tetradecanoylphorbol Acetate] results in increased expression of SPP1 mRNA |
CTD |
PMID:19840844 |
|
NCBI chr14:6,673,686...6,679,965
Ensembl chr14:6,673,686...6,679,901
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G |
Sqle |
squalene epoxidase |
increases expression multiple interactions |
ISO |
Methylnitronitrosoguanidine results in increased expression of SQLE mRNA [Methylnitronitrosoguanidine co-treated with Okadaic Acid] results in increased expression of SQLE mRNA |
CTD |
PMID:12634122 PMID:19840844 |
|
NCBI chr 7:99,609,929...99,624,803
Ensembl chr 7:99,609,191...99,624,732
|
|
G |
Srsf7 |
serine and arginine rich splicing factor 7 |
decreases expression |
ISO |
Methylnitronitrosoguanidine results in decreased expression of SRSF7 mRNA |
CTD |
PMID:12634122 |
|
NCBI chr 6:2,879,312...2,886,505
Ensembl chr 6:2,880,518...2,886,465
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|
G |
Stk39 |
serine threonine kinase 39 |
decreases expression |
ISO |
Methylnitronitrosoguanidine results in decreased expression of STK39 mRNA |
CTD |
PMID:12634122 |
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NCBI chr 3:54,359,449...54,625,702
Ensembl chr 3:54,359,451...54,625,414
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G |
Sumo2 |
small ubiquitin-like modifier 2 |
multiple interactions |
ISO |
[Methylnitronitrosoguanidine co-treated with Cadmium Chloride] results in increased expression of SUMO2 mRNA; [Methylnitronitrosoguanidine co-treated with Okadaic Acid] results in increased expression of SUMO2 mRNA; [Methylnitronitrosoguanidine co-treated with Tetradecanoylphorbol Acetate] results in increased expression of SUMO2 mRNA |
CTD |
PMID:19840844 |
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NCBI chr10:104,085,401...104,097,983
Ensembl chr10:104,086,002...104,097,812
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G |
Syn1 |
synapsin I |
multiple interactions |
ISO |
[Methylnitronitrosoguanidine co-treated with Cadmium Chloride] results in increased expression of SYN1 mRNA; [Methylnitronitrosoguanidine co-treated with Okadaic Acid] results in increased expression of SYN1 mRNA; [Methylnitronitrosoguanidine co-treated with Tetradecanoylphorbol Acetate] results in increased expression of SYN1 mRNA |
CTD |
PMID:19840844 |
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NCBI chr X:1,321,315...1,379,202
Ensembl chr X:1,321,315...1,379,198
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G |
Tbrg4 |
transforming growth factor beta regulator 4 |
increases expression |
ISO |
Methylnitronitrosoguanidine results in increased expression of TBRG4 mRNA |
CTD |
PMID:12634122 |
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NCBI chr14:86,876,800...86,885,603
Ensembl chr14:86,877,627...86,885,584
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G |
Tgfb1 |
transforming growth factor, beta 1 |
increases expression multiple interactions |
EXP |
Methylnitronitrosoguanidine results in increased expression of TGFB1 mRNA geraniol inhibits the reaction [Methylnitronitrosoguanidine results in increased expression of TGFB1 mRNA] |
CTD |
PMID:28428697 |
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NCBI chr 1:82,480,875...82,497,196
Ensembl chr 1:82,480,195...82,497,199
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G |
Thbs1 |
thrombospondin 1 |
multiple interactions |
ISO |
[Methylnitronitrosoguanidine co-treated with Cadmium Chloride] results in decreased expression of THBS1 mRNA; [Methylnitronitrosoguanidine co-treated with Okadaic Acid] results in decreased expression of THBS1 mRNA; [Methylnitronitrosoguanidine co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of THBS1 mRNA |
CTD |
PMID:19840844 |
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NCBI chr 3:109,862,120...109,873,466
Ensembl chr 3:109,862,117...109,873,466
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G |
Thbs2 |
thrombospondin 2 |
multiple interactions |
ISO |
[Methylnitronitrosoguanidine co-treated with Cadmium Chloride] results in decreased expression of THBS2 mRNA; [Methylnitronitrosoguanidine co-treated with Okadaic Acid] results in decreased expression of THBS2 mRNA; [Methylnitronitrosoguanidine co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of THBS2 mRNA |
CTD |
PMID:19840844 |
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NCBI chr 1:56,653,929...56,683,571
Ensembl chr 1:56,653,938...56,683,731
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G |
Tiam1 |
TIAM Rac1 associated GEF 1 |
increases expression |
ISO |
Methylnitronitrosoguanidine results in increased expression of TIAM1 mRNA |
CTD |
PMID:12634122 |
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NCBI chr11:29,931,083...30,061,173
Ensembl chr11:29,933,163...30,051,103
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G |
Timp2 |
TIMP metallopeptidase inhibitor 2 |
decreases expression multiple interactions |
EXP ISO |
Methylnitronitrosoguanidine results in decreased expression of TIMP2 mRNA; Methylnitronitrosoguanidine results in decreased expression of TIMP2 protein [Methylnitronitrosoguanidine co-treated with Cadmium Chloride] results in decreased expression of TIMP2 mRNA; [Methylnitronitrosoguanidine co-treated with Okadaic Acid] results in decreased expression of TIMP2 mRNA; [Methylnitronitrosoguanidine co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of TIMP2 mRNA Eugenol inhibits the reaction [Methylnitronitrosoguanidine results in decreased expression of TIMP2 mRNA]; Eugenol inhibits the reaction [Methylnitronitrosoguanidine results in decreased expression of TIMP2 protein] |
CTD |
PMID:19840844 PMID:20434464 |
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NCBI chr10:107,338,465...107,386,072
Ensembl chr10:107,338,465...107,386,072
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G |
Tlr4 |
toll-like receptor 4 |
increases expression |
EXP |
Methylnitronitrosoguanidine results in increased expression of TLR4 mRNA |
CTD |
PMID:15120970 |
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NCBI chr 5:82,587,424...82,601,056
Ensembl chr 5:82,587,420...82,601,052
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G |
Tmsb4x |
thymosin beta 4, X-linked |
multiple interactions |
ISO |
[Methylnitronitrosoguanidine co-treated with Okadaic Acid] results in increased expression of TMSB4X mRNA |
CTD |
PMID:19840844 |
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NCBI chr X:28,593,405...28,617,267
Ensembl chr X:28,593,405...28,595,395
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G |
Tnc |
tenascin C |
increases expression |
ISO |
Methylnitronitrosoguanidine results in increased expression of TNC mRNA |
CTD |
PMID:12634122 |
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NCBI chr 5:79,789,686...79,874,555
Ensembl chr 5:79,789,671...79,874,671
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G |
Tnfrsf25 |
TNF receptor superfamily member 25 |
increases expression |
ISO |
Methylnitronitrosoguanidine results in increased expression of TNFRSF25 mRNA |
CTD |
PMID:12634122 |
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NCBI chr 5:169,288,419...169,293,137
Ensembl chr 5:169,288,871...169,293,137
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G |
Top2a |
DNA topoisomerase II alpha |
multiple interactions |
ISO |
[Methylnitronitrosoguanidine co-treated with Cadmium Chloride] results in increased expression of TOP2A mRNA; [Methylnitronitrosoguanidine co-treated with Okadaic Acid] results in increased expression of TOP2A mRNA; [Methylnitronitrosoguanidine co-treated with Tetradecanoylphorbol Acetate] results in increased expression of TOP2A mRNA |
CTD |
PMID:19840844 |
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NCBI chr10:86,901,467...86,930,947
Ensembl chr10:86,901,007...86,932,154
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G |
Tp53 |
tumor protein p53 |
increases expression multiple interactions decreases expression increases acetylation increases response to substance decreases response to substance |
ISO EXP |
Methylnitronitrosoguanidine results in increased expression of TP53 mRNA; Methylnitronitrosoguanidine results in increased expression of TP53 protein ATR protein promotes the reaction [Methylnitronitrosoguanidine results in increased expression of TP53 protein]; CHEK2 protein promotes the reaction [Methylnitronitrosoguanidine results in increased expression of TP53 protein]; Methylnitronitrosoguanidine inhibits the reaction [TP53 protein binds to KDM8 protein]; TP53 protein mutant form inhibits the reaction [Methylnitronitrosoguanidine results in increased expression of RRM2B protein] Methylnitronitrosoguanidine results in increased expression of TRP53 protein [Methylnitronitrosoguanidine co-treated with Cadmium Chloride] results in increased expression of TRP53 mRNA; Cadmium Chloride inhibits the reaction [Methylnitronitrosoguanidine results in increased expression of TRP53 protein] Methylnitronitrosoguanidine results in decreased expression of TP53 protein Eugenol inhibits the reaction [Methylnitronitrosoguanidine results in decreased expression of TP53 protein]; resveratrol inhibits the reaction [Methylnitronitrosoguanidine results in increased acetylation of TP53 protein] TP53 protein results in increased susceptibility to Methylnitronitrosoguanidine TP53 protein mutant form results in decreased susceptibility to Methylnitronitrosoguanidine |
CTD |
PMID:9667752 PMID:11516527 PMID:12135628 PMID:12634122 PMID:15589979 PMID:17147953 PMID:19851710 PMID:26025680 PMID:26921499 |
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NCBI chr10:56,186,299...56,198,449
Ensembl chr10:56,187,020...56,198,449
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G |
Tram1 |
translocation associated membrane protein 1 |
increases expression |
ISO |
Methylnitronitrosoguanidine results in increased expression of TRAM1 mRNA |
CTD |
PMID:12634122 |
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NCBI chr 5:5,215,196...5,297,337
Ensembl chr 5:5,215,196...5,316,685
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G |
Tsc22d1 |
TSC22 domain family, member 1 |
decreases expression |
ISO |
Methylnitronitrosoguanidine results in decreased expression of TSC22D1 mRNA |
CTD |
PMID:12634122 |
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NCBI chr15:58,554,358...58,658,156
Ensembl chr15:58,554,374...58,658,153
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G |
Ttc3 |
tetratricopeptide repeat domain 3 |
multiple interactions |
ISO |
[Methylnitronitrosoguanidine co-treated with Cadmium Chloride] results in decreased expression of TTC3 mRNA; [Methylnitronitrosoguanidine co-treated with Okadaic Acid] results in decreased expression of TTC3 mRNA; [Methylnitronitrosoguanidine co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of TTC3 mRNA |
CTD |
PMID:19840844 |
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NCBI chr11:34,598,324...34,739,986
Ensembl chr11:34,598,492...34,738,791
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G |
Txn1 |
thioredoxin 1 |
multiple interactions |
ISO |
[Methylnitronitrosoguanidine co-treated with Cadmium Chloride] results in increased expression of TXN1 mRNA; [Methylnitronitrosoguanidine co-treated with Okadaic Acid] results in increased expression of TXN1 mRNA; [Methylnitronitrosoguanidine co-treated with Tetradecanoylphorbol Acetate] results in increased expression of TXN1 mRNA |
CTD |
PMID:19840844 |
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NCBI chr 5:75,049,735...75,057,731
Ensembl chr 5:75,049,747...75,057,752
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G |
Ubc |
ubiquitin C |
multiple interactions |
ISO |
[Methylnitronitrosoguanidine co-treated with Cadmium Chloride] results in decreased expression of UBC mRNA; [Methylnitronitrosoguanidine co-treated with Okadaic Acid] results in decreased expression of UBC mRNA; [Methylnitronitrosoguanidine co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of UBC mRNA |
CTD |
PMID:19840844 |
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NCBI chr12:36,638,457...36,642,734
Ensembl chr12:36,638,457...36,642,734
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G |
Uchl1 |
ubiquitin C-terminal hydrolase L1 |
increases expression |
ISO |
Methylnitronitrosoguanidine results in increased expression of UCHL1 mRNA |
CTD |
PMID:12634122 |
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NCBI chr14:43,133,224...43,143,942
Ensembl chr14:43,133,218...43,143,973
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G |
Ucp2 |
uncoupling protein 2 |
multiple interactions |
ISO |
[Methylnitronitrosoguanidine co-treated with Okadaic Acid] results in increased expression of UCP2 mRNA |
CTD |
PMID:19840844 |
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NCBI chr 1:165,506,375...165,512,744
Ensembl chr 1:165,506,361...165,512,744
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G |
Vim |
vimentin |
increases expression |
ISO |
Methylnitronitrosoguanidine results in increased expression of VIM mRNA |
CTD |
PMID:12634122 PMID:12773770 |
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NCBI chr17:80,882,715...80,891,200
Ensembl chr17:80,882,666...80,891,212
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G |
Wars1 |
tryptophanyl-tRNA synthetase 1 |
decreases expression |
ISO |
Methylnitronitrosoguanidine results in decreased expression of WARS1 mRNA |
CTD |
PMID:12634122 |
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NCBI chr 6:132,771,026...132,802,262
Ensembl chr 6:132,771,021...132,802,210
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G |
Wnt2 |
Wnt family member 2 |
increases expression |
ISO< | |