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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:geneticin
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Accession:CHEBI:42768 term browser browse the term
Definition:An aminoglycoside antibiotic produced by Micromonospora rhodorangea. It blocks polypeptide synthesis by inhibiting the elongation step in both prokaryotic and eukaryotic cells.
Synonyms:exact_synonym: (1R,2S,3S,4R,6S)-4,6-diamino-3-[3-deoxy-4-C-methyl-3-(methylamino)-beta-L-arabinopyranosyloxy]-2-hydroxycyclohexyl 2-amino-2,7-dideoxy-D-glycero-alpha-D-gluco-heptopyranoside
 related_synonym: Formula=C20H40N4O10;   G 418;   G418;   InChI=1S/C20H40N4O10/c1-6(25)14-11(27)10(26)9(23)18(32-14)33-15-7(21)4-8(22)16(12(15)28)34-19-13(29)17(24-3)20(2,30)5-31-19/h6-19,24-30H,4-5,21-23H2,1-3H3/t6?,7-,8+,9+,10+,11-,12-,13+,14+,15+,16-,17+,18+,19+,20-/m0/s1;   InChIKey=BRZYSWJRSDMWLG-CAXSIQPQSA-N;   SMILES=CN[C@@H]1[C@@H](O)[C@H](OC[C@]1(C)O)O[C@H]1[C@H](N)C[C@H](N)[C@@H](O[C@H]2O[C@H](C(C)O)[C@@H](O)[C@H](O)[C@H]2N)[C@@H]1O;   antibiotic G 418
 alt_id: CHEBI:33028;   CHEBI:42764
 xref: Beilstein:1669188;   CAS:49863-47-0;   DrugBank:DB04263;   KEGG:C17703
 xref_mesh: MESH:C010680
 xref: PDBeChem:GET
 cyclic_relationship: is_conjugate_base_of CHEBI:195256


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Path 1
Term Annotations click to browse term
  CHEBI ontology 5052
    role 5044
      biological role 5016
        antimicrobial agent 256
          carbohydrate-containing antibiotic 7
            aminoglycoside antibiotic 7
              geneticin 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 5052
    subatomic particle 5043
      composite particle 5043
        hadron 5071
          baryon 5043
            nucleon 5043
              atomic nucleus 5043
                atom 5043
                  main group element atom 5013
                    p-block element atom 5010
                      carbon group element atom 4927
                        carbon atom 4954
                          organic molecular entity 4926
                            heteroorganic entity 4768
                              organochalcogen compound 4730
                                organooxygen compound 4692
                                  carbohydrates and carbohydrate derivatives 123
                                    carbohydrate 125
                                      carbohydrate derivative 114
                                        glycosyl compound 50
                                          glycoside 25
                                            aminoglycoside 14
                                              aminoglycoside antibiotic 7
                                                geneticin 0
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