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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:aldehydo-D-glucose
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Accession:CHEBI:42758 term browser browse the term
Definition:The open chain form of D-glucose.
Synonyms:exact_synonym: aldehydo-D-gluco-hexose
 related_synonym: (2R,3S,4R,5R)-2,3,4,5,6-pentahydroxyhexanal;   D-GLUCOSE IN LINEAR FORM;   D-glucose;   Dextrose;   Formula=C6H12O6;   Glucose;   InChI=1S/C6H12O6/c7-1-3(9)5(11)6(12)4(10)2-8/h1,3-6,8-12H,2H2/t3-,4+,5+,6+/m0/s1;   InChIKey=GZCGUPFRVQAUEE-SLPGGIOYSA-N;   SMILES=[H]C(=O)[C@H](O)[C@@H](O)[C@H](O)[C@H](O)CO
 alt_id: CHEBI:37625;   CHEBI:42756
 xref: Beilstein:1724615;   CAS:50-99-7;   DrugBank:DB01914;   GlyGen:G59743JO;   GlyTouCan:G59743JO;   Gmelin:306224
 xref_mesh: MESH:D005947
 xref: PDBeChem:GLO;   Wikipedia:Glucose
 cyclic_relationship: is_enantiomer_of CHEBI:37626


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aldehydo-D-glucose term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcb1a ATP binding cassette subfamily B member 1A decreases expression ISO Glucose results in decreased expression of ABCB1 protein CTD PMID:22363694 NCBI chr 4:22,339,829...22,517,642
Ensembl chr 4:22,133,521...22,425,515
JBrowse link
G Abcb7 ATP binding cassette subfamily B member 7 decreases expression ISO Glucose results in decreased expression of ABCB7 mRNA CTD PMID:17178593 NCBI chr  X:75,150,511...75,291,950
Ensembl chr  X:75,150,608...75,291,938
JBrowse link
G Abcc1 ATP binding cassette subfamily C member 1 multiple interactions ISO Glucose inhibits the reaction [Sodium Azide inhibits the reaction [ABCC1 protein results in decreased uptake of Daunorubicin]]; Glucose inhibits the reaction [Sodium Azide inhibits the reaction [ABCC1 protein results in decreased uptake of Etoposide]] CTD PMID:10856430 NCBI chr10:549,537...672,235
Ensembl chr10:549,883...672,196
JBrowse link
G Abcc2 ATP binding cassette subfamily C member 2 multiple interactions EXP [Benzbromarone results in decreased activity of ABCC2 protein] inhibits the reaction [Glucose results in increased secretion of S-(2,4-dinitrophenyl)glutathione]; [Furosemide results in increased activity of ABCC2 protein] promotes the reaction [Glucose results in increased secretion of S-(2,4-dinitrophenyl)glutathione]; [sulfanitran results in increased activity of ABCC2 protein] promotes the reaction [Glucose results in increased secretion of S-(2,4-dinitrophenyl)glutathione] CTD PMID:19782883 NCBI chr 1:263,554,426...263,612,556
Ensembl chr 1:263,554,453...263,613,252
JBrowse link
G Acaca acetyl-CoA carboxylase alpha multiple interactions
increases expression
decreases phosphorylation
ISO
EXP
[INS protein co-treated with Glucose] results in increased expression of ACACA mRNA; [Pyruvic Acid co-treated with Glucose] results in increased phosphorylation of ACACA protein; PRKAA2 protein promotes the reaction [SIRT1 protein inhibits the reaction [Glucose results in decreased phosphorylation of ACACA protein]]; SIRT1 protein inhibits the reaction [Glucose results in decreased phosphorylation of ACACA protein]; SRT1720 inhibits the reaction [[INS protein co-treated with Glucose] results in increased expression of ACACA mRNA]
Glucose results in increased expression of ACACA mRNA
CTD PMID:15066988 PMID:18482975 PMID:19071085 PMID:19724016 PMID:24349266 NCBI chr10:71,519,392...71,719,910
Ensembl chr10:71,536,533...71,719,910
JBrowse link
G Ace angiotensin I converting enzyme increases expression
decreases expression
multiple interactions
ISO Glucose results in increased expression of ACE protein
Glucose results in decreased expression of ACE mRNA
Enalaprilat inhibits the reaction [Glucose results in increased expression of ACE protein]
CTD PMID:16452552 PMID:31655124 NCBI chr10:94,170,766...94,213,831
Ensembl chr10:94,170,766...94,187,822
JBrowse link
G Ache acetylcholinesterase multiple interactions
decreases activity
ISO Ascorbic Acid inhibits the reaction [Glucose results in decreased activity of ACHE protein] CTD PMID:26163454 NCBI chr12:22,472,358...22,477,052
Ensembl chr12:22,472,358...22,478,753
JBrowse link
G Acly ATP citrate lyase increases expression EXP
ISO
Glucose results in increased expression of ACLY mRNA
Glucose deficiency results in increased expression of ACLY mRNA; Glucose deficiency results in increased expression of ACLY protein
CTD PMID:24349266 PMID:26811028 NCBI chr10:88,392,248...88,442,845
Ensembl chr10:88,392,248...88,442,845
JBrowse link
G Aco1 aconitase 1 multiple interactions EXP [Oxygen deficiency co-treated with Glucose deficiency] affects the activity of ACO1 protein; Oxygen inhibits the reaction [[Oxygen deficiency co-treated with Glucose deficiency] affects the activity of ACO1 protein] CTD PMID:16135072 NCBI chr 5:56,425,076...56,481,218
Ensembl chr 5:56,425,024...56,481,218
JBrowse link
G Aco2 aconitase 2 multiple interactions EXP [Glucose co-treated with Oxygen] affects the activity of ACO2 protein; Glucose results in decreased expression of and results in decreased activity of ACO2 protein; LONP1 protein affects the reaction [SRT1720 inhibits the reaction [Glucose results in decreased expression of and results in decreased activity of ACO2 protein]]; manganese tetrakis-(N-ethyl-2 pyridyl) porphyrin inhibits the reaction [[Glucose co-treated with Oxygen] affects the activity of ACO2 protein]; manganese(III)-tetrakis(4-benzoic acid)porphyrin inhibits the reaction [[Glucose co-treated with Oxygen] affects the activity of ACO2 protein]; SRT1720 inhibits the reaction [Glucose results in decreased expression of and results in decreased activity of ACO2 protein] CTD PMID:11520895 PMID:31639451 NCBI chr 7:123,102,493...123,145,608
Ensembl chr 7:123,102,468...123,145,635
JBrowse link
G Acot1 acyl-CoA thioesterase 1 increases expression ISO Glucose results in increased expression of ACOT1 mRNA CTD PMID:17178593 NCBI chr 6:107,485,088...107,493,082
Ensembl chr 6:107,485,249...107,493,798
JBrowse link
G Acox2 acyl-CoA oxidase 2 decreases expression ISO Glucose results in decreased expression of ACOX2 mRNA CTD PMID:17178593 NCBI chr15:18,449,304...18,481,472
Ensembl chr15:18,451,144...18,481,470
JBrowse link
G Acsm2 acyl-CoA synthetase medium-chain family member 2 increases expression ISO Glucose results in increased expression of ACSM2 mRNA CTD PMID:31525975 NCBI chr 1:189,289,957...189,329,007
Ensembl chr 1:189,289,957...189,395,276
JBrowse link
G Acta1 actin, alpha 1, skeletal muscle increases expression
multiple interactions
EXP Glucose results in increased expression of ACTA1 mRNA
HMOX1 protein affects the reaction [Propofol inhibits the reaction [Glucose results in increased expression of ACTA1 mRNA]]; Propofol inhibits the reaction [Glucose results in increased expression of ACTA1 mRNA]; STAT3 protein affects the reaction [Propofol inhibits the reaction [Glucose results in increased expression of ACTA1 mRNA]]
CTD PMID:24810525 NCBI chr19:56,674,072...56,677,084
Ensembl chr19:56,674,074...56,677,084
JBrowse link
G Acta2 actin alpha 2, smooth muscle multiple interactions
increases expression
ISO
EXP
[Glucose co-treated with TGFB1 protein] results in increased expression of ACTA2 protein; C646 compound inhibits the reaction [Glucose results in increased expression of ACTA2 protein]; DKK1 protein inhibits the reaction [Glucose results in increased expression of ACTA2 mRNA]; DKK1 protein inhibits the reaction [Glucose results in increased expression of ACTA2 protein]; MAPK14 protein promotes the reaction [[Glucose co-treated with TGFB1 protein] results in increased expression of ACTA2 protein]; MAPK14 protein promotes the reaction [Glucose results in increased expression of ACTA2 protein]
Glucose results in increased expression of ACTA2 mRNA; Glucose results in increased expression of ACTA2 protein
cinnamic aldehyde inhibits the reaction [Glucose results in increased expression of ACTA2 protein]
CTD PMID:20060012 PMID:21829520 PMID:26045780 PMID:29163160 NCBI chr 1:252,537,614...252,550,394
Ensembl chr 1:252,537,615...252,550,394
JBrowse link
G Actb actin, beta decreases expression ISO Glucose deficiency results in decreased expression of ACTB protein CTD PMID:22314686 NCBI chr12:13,715,843...13,718,813
Ensembl chr12:13,715,843...13,718,841
JBrowse link
G Actg1 actin, gamma 1 multiple interactions EXP ACTG1 protein results in decreased susceptibility to [Oxygen deficiency co-treated with Glucose deficiency] CTD PMID:21124846 NCBI chr10:109,518,429...109,521,288
Ensembl chr 3:75,643,054...75,644,954
Ensembl chr10:75,643,054...75,644,954
JBrowse link
G Actr2 actin related protein 2 multiple interactions
decreases expression
ISO Eucalyptol inhibits the reaction [Glucose results in decreased expression of ACTR2 protein] CTD PMID:31483951 NCBI chr14:104,338,486...104,375,840
Ensembl chr14:104,340,434...104,375,649
JBrowse link
G Adam17 ADAM metallopeptidase domain 17 decreases expression ISO Glucose results in decreased expression of ADAM17 mRNA CTD PMID:31655124 NCBI chr 6:43,400,525...43,448,280
Ensembl chr 6:43,400,528...43,448,280
JBrowse link
G Adam8 ADAM metallopeptidase domain 8 increases expression ISO Glucose results in increased expression of ADAM8 mRNA CTD PMID:17178593 NCBI chr 1:212,317,510...212,332,895
Ensembl chr 1:212,317,848...212,330,349
JBrowse link
G Adamts1 ADAM metallopeptidase with thrombospondin type 1 motif, 1 increases expression ISO Glucose results in increased expression of ADAMTS1 mRNA CTD PMID:17178593 NCBI chr11:25,342,119...25,350,938
Ensembl chr11:25,342,126...25,350,974
JBrowse link
G Adhfe1 alcohol dehydrogenase, iron containing, 1 decreases expression ISO Glucose results in decreased expression of ADHFE1 mRNA CTD PMID:17178593 NCBI chr 5:9,403,194...9,429,783
Ensembl chr 5:9,403,196...9,429,859
JBrowse link
G Adipoq adiponectin, C1Q and collagen domain containing decreases expression
increases expression
multiple interactions
increases secretion
EXP
ISO
Glucose results in decreased expression of ADIPOQ protein
Glucose results in increased expression of ADIPOQ protein
[Glucose co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with INS1 protein] results in increased expression of ADIPOQ mRNA; [Glucose co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with INS1 protein] results in increased expression of ADIPOQ protein; avobenzone promotes the reaction [[Glucose co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with INS1 protein] results in increased expression of ADIPOQ mRNA]; avobenzone promotes the reaction [[Glucose co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with INS1 protein] results in increased expression of ADIPOQ protein]; butylbenzyl phthalate promotes the reaction [[Glucose co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with INS1 protein] results in increased expression of ADIPOQ protein]; Diethylhexyl Phthalate promotes the reaction [[Glucose co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with INS1 protein] results in increased expression of ADIPOQ protein]; dioxybenzone promotes the reaction [[Glucose co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with INS1 protein] results in increased expression of ADIPOQ mRNA]; dioxybenzone promotes the reaction [[Glucose co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with INS1 protein] results in increased expression of ADIPOQ protein]; oxybenzone promotes the reaction [[Glucose co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with INS1 protein] results in increased expression of ADIPOQ mRNA]; oxybenzone promotes the reaction [[Glucose co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with INS1 protein] results in increased expression of ADIPOQ protein]; Pioglitazone promotes the reaction [[Glucose co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with INS1 protein] results in increased expression of ADIPOQ protein]; tributyltin promotes the reaction [[Glucose co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with INS1 protein] results in increased expression of ADIPOQ protein]
Glucose deficiency results in increased secretion of ADIPOQ protein
ADIPOQ protein inhibits the reaction [Glucose results in decreased expression of ADIPOR2 protein]; argan oil promotes the reaction [Glucose results in increased expression of ADIPOQ protein]; Corn Oil promotes the reaction [Glucose results in increased expression of ADIPOQ protein]
CTD PMID:21912612 PMID:24802182 PMID:29165388 PMID:32407875 NCBI chr11:81,330,845...81,344,488
Ensembl chr11:81,330,293...81,344,488
JBrowse link
G Adipor1 adiponectin receptor 1 multiple interactions
decreases expression
EXP FOXO1 protein inhibits the reaction [Glucose results in decreased expression of ADIPOR1 mRNA]; FOXO1 protein inhibits the reaction [Glucose results in decreased expression of ADIPOR1 protein]; FOXO1 protein promotes the reaction [Resveratrol inhibits the reaction [Glucose results in decreased expression of ADIPOR1 mRNA]]; FOXO1 protein promotes the reaction [Resveratrol inhibits the reaction [Glucose results in decreased expression of ADIPOR1 protein]]; Resveratrol inhibits the reaction [Glucose results in decreased expression of ADIPOR1 mRNA]; Resveratrol inhibits the reaction [Glucose results in decreased expression of ADIPOR1 protein]
Glucose results in decreased expression of ADIPOR1 mRNA; Glucose results in decreased expression of ADIPOR1 protein
CTD PMID:24413998 NCBI chr13:51,240,470...51,260,233
Ensembl chr13:51,240,911...51,260,228
JBrowse link
G Adipor2 adiponectin receptor 2 multiple interactions
decreases expression
EXP ADIPOQ protein inhibits the reaction [Glucose results in decreased expression of ADIPOR2 protein] CTD PMID:21912612 NCBI chr 4:151,412,135...151,480,108
Ensembl chr 4:151,414,684...151,428,894
JBrowse link
G Adra1a adrenoceptor alpha 1A multiple interactions EXP 1,2-bis(2-aminophenoxy)ethane N,N,N',N'-tetraacetic acid acetoxymethyl ester inhibits the reaction [[cirazoline results in increased activity of ADRA1A protein] which results in increased transport of Glucose]; 1-(6-((3-methoxyestra-1,3,5(10)-trien-17-yl)amino)hexyl)-1H-pyrrole-2,5-dione inhibits the reaction [[cirazoline results in increased activity of ADRA1A protein] which results in increased transport of Glucose]; 2-(1-(3-dimethylaminopropyl)-5-methoxyindol-3-yl)-3-(1H-indol-3-yl)maleimide inhibits the reaction [[cirazoline results in increased activity of ADRA1A protein] which results in increased transport of Glucose]; 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [[cirazoline results in increased activity of ADRA1A protein] which results in increased transport of Glucose]; 4-(4-fluorophenyl)-2-(4-hydroxyphenyl)-5-(4-pyridyl)imidazole inhibits the reaction [[cirazoline results in increased activity of ADRA1A protein] which results in increased transport of Glucose]; [cirazoline results in increased activity of ADRA1A protein] which results in increased transport of Glucose; [Phenylephrine results in increased activity of ADRA1A protein] which results in increased transport of Glucose; Prazosin inhibits the reaction [[cirazoline results in increased activity of ADRA1A protein] which results in increased transport of Glucose] CTD PMID:15550506 NCBI chr15:43,296,997...43,398,314
Ensembl chr15:43,298,794...43,392,451
JBrowse link
G Adrb2 adrenoceptor beta 2 multiple interactions ISO [BRL 37344 binds to and results in increased activity of ADRB2 protein] which results in increased uptake of Glucose; [Clenbuterol binds to and results in increased activity of ADRB2 protein] which results in decreased uptake of Glucose; ICI 118551 inhibits the reaction [[BRL 37344 binds to and results in increased activity of ADRB2 protein] which results in increased uptake of Glucose]; ICI 118551 inhibits the reaction [[Clenbuterol binds to and results in increased activity of ADRB2 protein] which results in decreased uptake of Glucose] CTD PMID:18552870 NCBI chr18:57,513,792...57,515,834
Ensembl chr18:57,513,793...57,515,834
JBrowse link
G Adrb3 adrenoceptor beta 3 multiple interactions ISO [BRL 37344 binds to and results in increased activity of ADRB3 protein] which results in decreased abundance of Glucose CTD PMID:20930473 NCBI chr16:69,003,541...69,006,632
Ensembl chr16:69,003,868...69,006,632
JBrowse link
G Afp alpha-fetoprotein increases expression ISO Glucose results in increased expression of AFP mRNA CTD PMID:17178593 NCBI chr14:19,141,755...19,159,919
Ensembl chr14:19,141,755...19,159,923
JBrowse link
G Ager advanced glycosylation end product-specific receptor multiple interactions
increases expression
ISO
EXP
GLO1 inhibits the reaction [Glucose promotes the reaction [RELA protein binds to AGER promoter]]; GLO1 inhibits the reaction [Glucose results in increased expression of AGER mRNA]; GLO1 inhibits the reaction [Glucose results in increased expression of AGER protein]; Glucose promotes the reaction [RELA protein binds to AGER promoter]; Luteolin inhibits the reaction [Glucose results in increased expression of AGER mRNA]; Quercetin inhibits the reaction [Glucose results in increased expression of AGER mRNA]; RELA promotes the reaction [Glucose results in increased expression of AGER mRNA]; Rutin inhibits the reaction [Glucose results in increased expression of AGER mRNA]; SOD2 inhibits the reaction [Glucose results in increased expression of AGER mRNA]; SOD2 inhibits the reaction [Glucose results in increased expression of AGER protein]; UCP1 inhibits the reaction [Glucose results in increased expression of AGER mRNA]; UCP1 inhibits the reaction [Glucose results in increased expression of AGER protein]
[Ribose co-treated with Glucose] results in increased expression of AGER protein; AGER protein affects the reaction [Ribose promotes the reaction [Glucose results in increased phosphorylation of RELA protein]]
Glucose results in increased expression of AGER mRNA; Glucose results in increased expression of AGER protein
AGER protein results in increased susceptibility to [Azoxymethane co-treated with Glucose co-treated with Linoleic Acid]; Glucose promotes the reaction [Azoxymethane results in increased expression of AGER protein]; Glucose promotes the reaction [Linoleic Acid promotes the reaction [Azoxymethane results in increased expression of AGER protein]]; Linoleic Acid promotes the reaction [Glucose promotes the reaction [Azoxymethane results in increased expression of AGER protein]]; Losartan inhibits the reaction [Glucose promotes the reaction [Linoleic Acid promotes the reaction [Azoxymethane results in increased expression of AGER protein]]]; Losartan inhibits the reaction [Linoleic Acid promotes the reaction [Glucose promotes the reaction [Azoxymethane results in increased expression of AGER protein]]]; Metformin inhibits the reaction [Glucose promotes the reaction [Linoleic Acid promotes the reaction [Azoxymethane results in increased expression of AGER protein]]]; Metformin inhibits the reaction [Linoleic Acid promotes the reaction [Glucose promotes the reaction [Azoxymethane results in increased expression of AGER protein]]]
CTD PMID:19557821 PMID:19759273 PMID:19833897 PMID:22467055 PMID:30101366 NCBI chr20:4,363,152...4,366,079
Ensembl chr20:4,363,152...4,366,079
JBrowse link
G Agl amylo-alpha-1, 6-glucosidase, 4-alpha-glucanotransferase increases uptake ISO AGL protein results in increased uptake of Glucose CTD PMID:24700805 NCBI chr 2:219,788,234...219,843,189
Ensembl chr 2:219,788,234...219,842,986
JBrowse link
G Agt angiotensinogen multiple interactions
increases expression
affects metabolic processing
ISO
EXP
(3,4-dihydroxyphenylamino)-2-imidazoline inhibits the reaction [Glucose promotes the reaction [AGT protein results in increased phosphorylation of JAK2 protein]]; 1,2-Dihydroxybenzene-3,5-Disulfonic Acid Disodium Salt inhibits the reaction [Glucose promotes the reaction [AGT protein results in increased phosphorylation of JAK2 protein]]; [Valsartan co-treated with Simvastatin] inhibits the reaction [Glucose promotes the reaction [AGT protein results in increased expression of CCL2 mRNA]]; [Valsartan co-treated with Simvastatin] inhibits the reaction [Glucose promotes the reaction [AGT protein results in increased expression of LIF mRNA]]; acetovanillone inhibits the reaction [Glucose promotes the reaction [AGT protein results in increased phosphorylation of JAK2 protein]]; Enalaprilat inhibits the reaction [Glucose results in increased expression of AGT protein]; Glucose promotes the reaction [AGT protein results in increased expression of CCL2 mRNA]; Glucose promotes the reaction [AGT protein results in increased expression of EGR1 mRNA]; Glucose promotes the reaction [AGT protein results in increased expression of FOSL1 mRNA]; Glucose promotes the reaction [AGT protein results in increased expression of KLF10 mRNA]; Glucose promotes the reaction [AGT protein results in increased expression of LIF mRNA]; Glucose promotes the reaction [AGT protein results in increased phosphorylation of JAK2 protein]; Rotenone inhibits the reaction [Glucose promotes the reaction [AGT protein results in increased phosphorylation of JAK2 protein]]; Simvastatin promotes the reaction [Glucose promotes the reaction [AGT protein results in increased expression of PTGS2 mRNA]]; Valsartan inhibits the reaction [Glucose promotes the reaction [AGT protein results in increased expression of CCL2 mRNA]]; Valsartan inhibits the reaction [Glucose promotes the reaction [AGT protein results in increased expression of EGR1 mRNA]]; Valsartan inhibits the reaction [Glucose promotes the reaction [AGT protein results in increased expression of KLF10 mRNA]]; Valsartan inhibits the reaction [Glucose promotes the reaction [AGT protein results in increased expression of LIF mRNA]]; Valsartan inhibits the reaction [Glucose promotes the reaction [AGT protein results in increased phosphorylation of JAK2 protein]]
Glucose results in increased expression of AGT mRNA; Glucose results in increased expression of AGT protein
AGT protein affects the metabolism of Glucose
1,2-Dihydroxybenzene-3,5-Disulfonic Acid Disodium Salt inhibits the reaction [Glucose results in increased expression of AGT mRNA]; 1,2-Dihydroxybenzene-3,5-Disulfonic Acid Disodium Salt inhibits the reaction [Glucose results in increased expression of AGT protein]; alpha-cyano-4-hydroxycinnamate inhibits the reaction [Glucose results in increased expression of AGT mRNA]; alpha-cyano-4-hydroxycinnamate inhibits the reaction [Glucose results in increased expression of AGT protein]; Carbonyl Cyanide m-Chlorophenyl Hydrazone inhibits the reaction [Glucose results in increased expression of AGT mRNA]; Carbonyl Cyanide m-Chlorophenyl Hydrazone inhibits the reaction [Glucose results in increased expression of AGT protein]; CAT protein inhibits the reaction [Glucose results in increased expression of AGT mRNA]; CAT protein inhibits the reaction [Glucose results in increased expression of AGT protein]; Hydrogen Peroxide promotes the reaction [Glucose results in increased expression of AGT mRNA]; Hydrogen Peroxide promotes the reaction [Glucose results in increased expression of AGT protein]; manganese(III)-tetrakis(4-benzoic acid)porphyrin inhibits the reaction [Glucose results in increased expression of AGT mRNA]; manganese(III)-tetrakis(4-benzoic acid)porphyrin inhibits the reaction [Glucose results in increased expression of AGT protein]; Rotenone inhibits the reaction [Glucose results in increased expression of AGT mRNA]; Rotenone inhibits the reaction [Glucose results in increased expression of AGT protein]; SB 203580 inhibits the reaction [Glucose results in increased expression of AGT mRNA]; SB 203580 inhibits the reaction [Glucose results in increased expression of AGT protein]; Taurine inhibits the reaction [Glucose results in increased expression of AGT mRNA]; Taurine inhibits the reaction [Glucose results in increased expression of AGT protein]; Thenoyltrifluoroacetone inhibits the reaction [Glucose results in increased expression of AGT mRNA]; Thenoyltrifluoroacetone inhibits the reaction [Glucose results in increased expression of AGT protein]; Valsartan promotes the reaction [Glucose results in increased expression of AGT protein]
CTD PMID:11115780 PMID:12130563 PMID:15677497 PMID:16452552 PMID:19225232 PMID:19861503 NCBI chr19:57,321,594...57,333,460
Ensembl chr19:57,321,640...57,333,433
JBrowse link
G Agtr1a angiotensin II receptor, type 1a increases expression
multiple interactions
ISO Glucose results in increased expression of AGTR1 mRNA; Glucose results in increased expression of AGTR1 protein
Enalaprilat inhibits the reaction [Glucose results in increased expression of AGTR1 protein]
CTD PMID:16452552 PMID:31655124 NCBI chr17:35,907,102...35,958,136
Ensembl chr17:35,907,108...35,958,077
JBrowse link
G Ahr aryl hydrocarbon receptor multiple interactions
increases response to substance
ISO 4,7-phenanthroline inhibits the reaction [AHR promotes the reaction [Tetrachlorodibenzodioxin results in decreased uptake of Glucose]]; AHR promotes the reaction [Tetrachlorodibenzodioxin results in decreased uptake of Glucose]; alpha-naphthoflavone inhibits the reaction [AHR promotes the reaction [Tetrachlorodibenzodioxin results in decreased uptake of Glucose]]
AHR results in increased susceptibility to Glucose
AHR protein promotes the reaction [Tetrachlorodibenzodioxin affects the susceptibility to Glucose]
CTD PMID:8738555 PMID:19623578 PMID:21849270 NCBI chr 6:54,963,990...55,001,806
Ensembl chr 6:54,963,990...55,001,464
JBrowse link
G Aifm1 apoptosis inducing factor, mitochondria associated 1 affects localization
multiple interactions
EXP Glucose affects the localization of AIFM1 protein
Quercetin affects the reaction [Glucose affects the localization of AIFM1 protein]; sesamin affects the reaction [Glucose affects the localization of AIFM1 protein]
CTD PMID:19146853 PMID:22524206 NCBI chr  X:135,304,063...135,343,062
Ensembl chr  X:135,304,066...135,343,087
JBrowse link
G Akap5 A-kinase anchoring protein 5 increases expression ISO Glucose results in increased expression of AKAP5 mRNA CTD PMID:31525975 NCBI chr 6:99,356,509...99,361,909
Ensembl chr 6:99,356,509...99,361,909
JBrowse link
G Akr1a1 aldo-keto reductase family 1 member A1 multiple interactions
decreases expression
ISO fidarestat inhibits the reaction [Glucose results in decreased expression of AKR1A1 mRNA] CTD PMID:16805838 NCBI chr 5:135,482,068...135,498,693
Ensembl chr 5:135,482,068...135,498,822
JBrowse link
G Akr1b1 aldo-keto reductase family 1 member B increases expression
multiple interactions
ISO Glucose results in increased expression of AKR1B3 mRNA; Glucose results in increased expression of AKR1B3 protein
AKR1B1 protein promotes the reaction [Glucose results in increased abundance of Sorbitol]
CTD PMID:16805838 PMID:25451566 NCBI chr 4:61,706,866...61,720,959
Ensembl chr 4:61,706,864...61,720,956
JBrowse link
G Akt1 AKT serine/threonine kinase 1 increases phosphorylation
decreases phosphorylation
multiple interactions
decreases expression
increases response to substance
ISO
EXP
Glucose results in increased phosphorylation of AKT1 protein
Glucose results in decreased phosphorylation of AKT1 protein
2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [deuterohemin-alanyl-histidyl-threonyl-valyl-glutamyl-lysine inhibits the reaction [Glucose results in decreased phosphorylation of AKT1 protein]]; 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [diallyl trisulfide inhibits the reaction [Glucose results in decreased phosphorylation of AKT1 protein]]; 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [Glucose results in increased phosphorylation of AKT1 protein]; 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [Quercetin inhibits the reaction [[Dithionite co-treated with Glucose deficiency] results in decreased phosphorylation of AKT1 protein]]; 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [Resveratrol inhibits the reaction [Glucose results in decreased phosphorylation of AKT1 protein]]; 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one promotes the reaction [[Dithionite co-treated with Glucose deficiency] results in decreased phosphorylation of AKT1 protein]; 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide inhibits the reaction [Glucose results in increased phosphorylation of AKT1 protein]; [3,4-Dihydroxyphenylacetic Acid co-treated with Glucose] results in increased phosphorylation of AKT1 protein; [Catechin co-treated with Glucose] results in increased phosphorylation of AKT1 protein; [Dithionite co-treated with Glucose deficiency] results in decreased phosphorylation of AKT1 protein; Acetylcysteine inhibits the reaction [Glucose results in decreased phosphorylation of AKT1 protein]; Acetylcysteine inhibits the reaction [Glucose results in increased phosphorylation of AKT1 protein]; deuterohemin-alanyl-histidyl-threonyl-valyl-glutamyl-lysine inhibits the reaction [Glucose results in decreased phosphorylation of AKT1 protein]; diallyl trisulfide inhibits the reaction [Glucose results in decreased phosphorylation of AKT1 protein]; Quercetin inhibits the reaction [[Dithionite co-treated with Glucose deficiency] results in decreased phosphorylation of AKT1 protein]; Resveratrol inhibits the reaction [Glucose results in decreased phosphorylation of AKT1 protein]; Resveratrol inhibits the reaction [Glucose results in increased phosphorylation of AKT1 protein]; Simvastatin inhibits the reaction [Glucose results in decreased expression of AKT1 protein modified form]
2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [SMARCA4A protein inhibits the reaction [Glucose results in decreased phosphorylation of AKT1 protein]]; [AKT1 protein mutant form results in increased susceptibility to Glucose deficiency] which results in increased phosphorylation of EIF4EBP1 protein; AICA ribonucleotide inhibits the reaction [AKT1 protein mutant form results in increased susceptibility to Glucose deficiency]; AKT1 protein modified form inhibits the reaction [arsenite inhibits the reaction [INS1 protein results in increased uptake of Glucose]]; AKT1 protein modified form inhibits the reaction [monomethylarsonous acid inhibits the reaction [INS1 protein results in increased uptake of Glucose]]; AKT1 protein promotes the reaction [Glucose affects the phosphorylation of and affects the activity of FOXO3 protein]; Bezafibrate inhibits the reaction [AKT1 protein mutant form results in increased susceptibility to Glucose deficiency]; Glucose affects the phosphorylation of and affects the activity of AKT1 protein; methyl pyruvate inhibits the reaction [AKT1 protein mutant form results in increased susceptibility to Glucose deficiency]; PRKAA2 protein affects the reaction [AICA ribonucleotide inhibits the reaction [AKT1 protein mutant form affects the susceptibility to Glucose deficiency]]; SMARCA4A protein inhibits the reaction [Glucose results in decreased phosphorylation of AKT1 protein]
2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [Resveratrol inhibits the reaction [Glucose results in decreased phosphorylation of AKT1 protein]]; 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [spiraeoside inhibits the reaction [Glucose results in decreased phosphorylation of AKT1 protein]]; 2-chloro-5-nitrobenzanilide inhibits the reaction [Rosiglitazone inhibits the reaction [Glucose results in decreased phosphorylation of AKT1 protein]]; [Glucose affects the susceptibility to INS protein] which affects the phosphorylation of AKT1 protein; Berberine inhibits the reaction [Glucose results in decreased phosphorylation of AKT1 protein]; Glucose inhibits the reaction [INS protein results in increased phosphorylation of AKT1 protein]; Metformin inhibits the reaction [Glucose results in increased phosphorylation of AKT1 protein]; N-(oxo-5,6-dihydrophenanthridin-2-yl)-N,N-dimethylacetamide hydrochloride inhibits the reaction [Glucose inhibits the reaction [INS protein results in increased phosphorylation of AKT1 protein]]; Resveratrol inhibits the reaction [Glucose results in decreased phosphorylation of AKT1 protein]; Rosiglitazone inhibits the reaction [Glucose results in decreased phosphorylation of AKT1 protein]; spiraeoside inhibits the reaction [Glucose results in decreased phosphorylation of AKT1 protein]
CTD PMID:15806154 PMID:16385087 PMID:17520061 PMID:18004065 PMID:20370652 PMID:21031461 PMID:21333731 PMID:21803128 PMID:23159718 PMID:23453443 PMID:23954465 PMID:24946264 PMID:24971582 PMID:25471227 PMID:26054749 PMID:27049278 PMID:29981789 PMID:30914352 PMID:32602595 PMID:33270355 NCBI chr 6:137,218,398...137,239,970
Ensembl chr 6:137,218,376...137,236,258
JBrowse link
G Akt2 AKT serine/threonine kinase 2 affects response to substance ISO AKT2 protein affects the susceptibility to Glucose CTD PMID:21964073 NCBI chr 1:84,400,939...84,451,223
Ensembl chr 1:84,411,726...84,450,162
JBrowse link
G Alb albumin multiple interactions
decreases uptake
increases metabolic processing
ISO
EXP
[Peroxynitrous Acid co-treated with Glucose] results in increased glycation of ALB protein; Phlorhizin inhibits the reaction [Glucose results in decreased uptake of ALB protein]; pimagedine inhibits the reaction [[Peroxynitrous Acid co-treated with Glucose] results in increased glycation of ALB protein]
ALB protein modified form inhibits the reaction [Glucose results in increased phosphorylation of RELA protein]; ALB protein modified form inhibits the reaction [Glucose results in increased secretion of INS1 protein]; MK615 extract inhibits the reaction [ALB protein modified form inhibits the reaction [Glucose results in increased phosphorylation of RELA protein]]; MK615 extract inhibits the reaction [ALB protein modified form inhibits the reaction [Glucose results in increased secretion of INS1 protein]]
[Glucose deficiency co-treated with ALB protein] results in decreased expression of FABP4 mRNA; [Glucose deficiency co-treated with ALB protein] results in decreased expression of PCK1 mRNA
Glucose results in increased metabolism of ALB protein
CTD PMID:8536680 PMID:12196478 PMID:12434198 PMID:16313995 PMID:27415824 NCBI chr14:19,176,275...19,191,793
Ensembl chr14:19,176,277...19,191,863
JBrowse link
G Aldh1b1 aldehyde dehydrogenase 1 family, member B1 increases expression ISO Glucose deficiency results in increased expression of ALDH1B1 protein CTD PMID:22314686 NCBI chr 5:61,382,351...61,387,359
Ensembl chr 5:61,382,351...61,387,358
JBrowse link
G Aldh2 aldehyde dehydrogenase 2 family member decreases expression
multiple interactions
EXP Glucose results in decreased expression of ALDH2 protein
N-(1,3-benzodioxol-5-ylmethyl)-2,6-dichlorobenzamide inhibits the reaction [Glucose results in decreased expression of ALDH2 protein]
CTD PMID:29128638 NCBI chr12:40,466,418...40,498,813
Ensembl chr12:40,466,495...40,498,752
JBrowse link
G Aldh6a1 aldehyde dehydrogenase 6 family, member A1 decreases expression ISO Glucose results in decreased expression of ALDH6A1 mRNA CTD PMID:17178593 NCBI chr 6:108,146,552...108,167,185
Ensembl chr 6:108,146,582...108,167,185
JBrowse link
G Alg12 ALG12, alpha-1,6-mannosyltransferase decreases expression ISO Glucose results in decreased expression of ALG12 mRNA CTD PMID:17178593 NCBI chr 7:129,798,663...129,812,677
Ensembl chr 7:129,798,663...129,812,388
JBrowse link
G Alox5 arachidonate 5-lipoxygenase multiple interactions
increases expression
EXP
ISO
[Oxygen deficiency co-treated with Glucose deficiency] affects the localization of ALOX5 protein; caffeic acid inhibits the reaction [[Oxygen deficiency co-treated with Glucose deficiency] affects the localization of ALOX5 protein]; Edaravone inhibits the reaction [[Oxygen deficiency co-treated with Glucose deficiency] affects the localization of ALOX5 protein]; SB 203580 inhibits the reaction [[Oxygen deficiency co-treated with Glucose deficiency] affects the localization of ALOX5 protein]
Glucose results in increased expression of ALOX5 mRNA
CTD PMID:18951527 PMID:31655124 NCBI chr 4:148,398,004...148,446,308
Ensembl chr 4:148,398,892...148,446,303
JBrowse link
G Amot angiomotin decreases expression ISO Glucose results in decreased expression of AMOT mRNA CTD PMID:17178593 NCBI chr  X:116,751,231...116,810,238
Ensembl chr  X:116,751,230...116,792,864
JBrowse link
G Angptl4 angiopoietin-like 4 increases expression ISO Glucose results in increased expression of ANGPTL4 mRNA CTD PMID:16805838 NCBI chr 7:18,627,814...18,634,043
Ensembl chr 7:18,627,808...18,634,079
JBrowse link
G Ankrd61 ankyrin repeat domain 61 decreases expression ISO Glucose results in decreased expression of ANKRD61 mRNA CTD PMID:31525975 NCBI chr12:12,756,480...12,760,838
Ensembl chr12:12,756,452...12,760,838
JBrowse link
G Anxa5 annexin A5 decreases expression ISO Glucose results in decreased expression of ANXA5 mRNA CTD PMID:31655124 NCBI chr 2:123,162,477...123,194,730
Ensembl chr 2:123,162,461...123,193,130
JBrowse link
G Apc APC regulator of WNT signaling pathway decreases expression EXP Glucose results in decreased expression of APC mRNA CTD PMID:21818840 NCBI chr18:27,011,710...27,106,323
Ensembl chr18:27,047,382...27,105,531
JBrowse link
G Apoa1 apolipoprotein A1 increases expression
decreases expression
EXP Glucose results in increased expression of APOA1 mRNA; Glucose results in increased expression of APOA1 protein
Glucose results in decreased expression of APOA1 mRNA
CTD PMID:9322794 PMID:9668074 NCBI chr 8:50,525,091...50,526,875
Ensembl chr 8:50,525,091...50,526,875
JBrowse link
G Apob apolipoprotein B multiple interactions ISO Glucose promotes the reaction [Copper Sulfate results in increased cleavage of APOB protein] CTD PMID:19489629 NCBI chr 6:33,176,826...33,216,381
Ensembl chr 6:33,176,778...33,224,997
JBrowse link
G Apoe apolipoprotein E affects secretion ISO Glucose deficiency affects the secretion of APOE protein CTD PMID:24802182 NCBI chr 1:80,612,894...80,616,820
Ensembl chr 1:80,612,895...80,617,057
JBrowse link
G Aqp1 aquaporin 1 increases expression
multiple interactions
EXP Glucose results in increased expression of AQP1 mRNA
benazepril inhibits the reaction [Glucose results in increased expression of AQP1 mRNA]; valsartan inhibits the reaction [Glucose results in increased expression of AQP1 mRNA]
CTD PMID:11510275 NCBI chr 4:85,551,503...85,563,683
Ensembl chr 4:85,551,502...85,569,360
JBrowse link
G Aqp3 aquaporin 3 (Gill blood group) multiple interactions
increases expression
ISO Glucose promotes the reaction [AQP3 protein results in increased transport of Glycerol]
Glucose results in increased expression of AQP3 mRNA; Glucose results in increased expression of AQP3 protein
CTD PMID:12234316 NCBI chr 5:57,423,735...57,429,252
Ensembl chr 5:57,423,734...57,429,245
JBrowse link
G Aqp4 aquaporin 4 multiple interactions
increases expression
EXP benazepril inhibits the reaction [Glucose results in increased expression of AQP4 mRNA]; valsartan inhibits the reaction [Glucose results in increased expression of AQP4 mRNA] CTD PMID:11510275 NCBI chr18:6,766,009...6,782,757
Ensembl chr18:6,765,945...6,782,996
JBrowse link
G Arg2 arginase 2 increases expression ISO Glucose results in increased expression of ARG2 mRNA CTD PMID:17178593 NCBI chr 6:102,311,097...102,338,406
Ensembl chr 6:102,311,116...102,338,520
JBrowse link
G Arhgap6 Rho GTPase activating protein 6 increases expression ISO Glucose results in increased expression of ARHGAP6 mRNA CTD PMID:31525975 NCBI chr  X:26,314,561...26,845,242
Ensembl chr  X:26,315,878...26,376,467
JBrowse link
G Arl4d ADP-ribosylation factor like GTPase 4D multiple interactions EXP [Oxygen deficiency co-treated with Glucose deficiency] results in increased expression of ARL4D mRNA; ARL4D protein results in decreased susceptibility to [Oxygen deficiency co-treated with Glucose deficiency] CTD PMID:21124846 NCBI chr10:89,577,556...89,580,368
Ensembl chr10:89,578,212...89,580,368
JBrowse link
G Arl5b ADP-ribosylation factor like GTPase 5B increases expression ISO Glucose results in increased expression of ARL5B mRNA CTD PMID:17178593 NCBI chr17:82,065,893...82,092,693
Ensembl chr17:82,065,937...82,091,362
JBrowse link
G Arnt aryl hydrocarbon receptor nuclear translocator multiple interactions
increases activity
ISO Glucose promotes the reaction [[ARNT protein binds to G6PC1 promoter] which results in increased expression of G6PC1 mRNA]
Glucose results in increased activity of ARNT protein
[Glucose co-treated with Oxygen deficiency] inhibits the reaction [ARNT protein binds to HIF1A protein]
CTD PMID:15767253 PMID:18227068 NCBI chr 2:196,594,178...196,651,486
Ensembl chr 2:196,594,303...196,651,179
JBrowse link
G Asns asparagine synthetase (glutamine-hydrolyzing) affects expression ISO Glucose affects the expression of ASNS mRNA CTD PMID:17409444 NCBI chr 4:33,742,876...33,761,106
Ensembl chr 4:33,743,364...33,761,163
JBrowse link
G Atad1 ATPase family, AAA domain containing 1 multiple interactions EXP ATAD1 protein results in decreased susceptibility to [Oxygen deficiency co-treated with Glucose deficiency] CTD PMID:21124846 NCBI chr 1:251,234,702...251,386,996
Ensembl chr 1:251,235,508...251,387,002
JBrowse link
G Atf4 activating transcription factor 4 increases expression
multiple interactions
ISO Glucose deficiency results in increased expression of ATF4 mRNA
Glucose deficiency results in increased expression of ATF4 protein
4-Quinolones analog inhibits the reaction [Glucose deficiency results in increased expression of ATF4 protein]; [Galactose co-treated with Glucose deficiency] promotes the reaction [Leflunomide results in increased expression of ATF4 protein]; salubrinal inhibits the reaction [4-Quinolones analog inhibits the reaction [Glucose deficiency results in increased expression of ATF4 protein]]
CTD PMID:27226639 PMID:29427785 PMID:31022492 NCBI chr 7:121,480,723...121,482,781
Ensembl chr 7:121,480,723...121,482,772
JBrowse link
G Atf6 activating transcription factor 6 increases expression
multiple interactions
ISO Glucose deficiency results in increased expression of ATF6 protein
4-Quinolones analog inhibits the reaction [Glucose deficiency results in increased expression of ATF6 protein]; ATF6 protein modified form promotes the reaction [4-Quinolones analog inhibits the reaction [Glucose deficiency results in increased expression of HSPA5 protein]]
CTD PMID:31022492 NCBI chr13:89,053,457...89,242,531
Ensembl chr13:89,055,983...89,242,443
JBrowse link
G Atg5 autophagy related 5 multiple interactions
decreases expression
EXP 3-methyladenine inhibits the reaction [N-(1,3-benzodioxol-5-ylmethyl)-2,6-dichlorobenzamide inhibits the reaction [Glucose results in decreased expression of ATG5 protein]]; N-(1,3-benzodioxol-5-ylmethyl)-2,6-dichlorobenzamide inhibits the reaction [Glucose results in decreased expression of ATG5 protein]; Sirolimus promotes the reaction [N-(1,3-benzodioxol-5-ylmethyl)-2,6-dichlorobenzamide inhibits the reaction [Glucose results in decreased expression of ATG5 protein]]; ULK1 protein affects the reaction [Glucose results in decreased expression of ATG5 protein]; ULK1 protein affects the reaction [N-(1,3-benzodioxol-5-ylmethyl)-2,6-dichlorobenzamide inhibits the reaction [Glucose results in decreased expression of ATG5 protein]] CTD PMID:29128638 NCBI chr20:49,301,783...49,393,147
Ensembl chr20:49,318,308...49,393,140
JBrowse link
G Atl1 atlastin GTPase 1 multiple interactions EXP ATL1 protein results in decreased susceptibility to [Oxygen deficiency co-treated with Glucose deficiency] CTD PMID:21124846 NCBI chr 6:92,229,764...92,370,428
Ensembl chr 6:92,229,686...92,370,421
JBrowse link
G Atp1a1 ATPase Na+/K+ transporting subunit alpha 1 multiple interactions ISO
EXP
Glucose results in decreased expression of and results in decreased activity of ATP1A1 protein; INS protein inhibits the reaction [Glucose results in decreased expression of ATP1A1 protein]
[Oxygen deficiency co-treated with Glucose deficiency] results in decreased expression of and affects the localization of ATP1A1 protein; Antigen-Antibody Complex inhibits the reaction [[Oxygen deficiency co-treated with Glucose deficiency] results in decreased expression of and affects the localization of ATP1A1 protein]
CTD PMID:22162761 PMID:29702141 NCBI chr 2:204,003,742...204,032,023
Ensembl chr 2:204,003,742...204,032,023
JBrowse link
G Atp2a1 ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 1 decreases expression ISO Glucose results in decreased expression of ATP2A1 mRNA CTD PMID:31525975 NCBI chr 1:197,855,912...197,875,038 JBrowse link
G Atp5f1a ATP synthase F1 subunit alpha multiple interactions EXP [Glucose deficiency co-treated with Galactose co-treated with Pyruvic Acid] results in increased expression of ATP5F1A protein CTD PMID:25997894 NCBI chr18:74,156,553...74,164,490
Ensembl chr18:74,156,553...74,164,495
JBrowse link
G Atp5f1d ATP synthase F1 subunit delta multiple interactions EXP 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid inhibits the reaction [notoginsenoside R1 inhibits the reaction [[Oxygen co-treated with [Oxygen deficiency co-treated with Glucose deficiency]] results in decreased expression of ATP5F1D protein]]; [Oxygen co-treated with [Oxygen deficiency co-treated with Glucose deficiency]] results in decreased expression of ATP5F1D protein; notoginsenoside R1 inhibits the reaction [[Oxygen co-treated with [Oxygen deficiency co-treated with Glucose deficiency]] results in decreased expression of ATP5F1D protein]; Y 27632 inhibits the reaction [[Oxygen co-treated with [Oxygen deficiency co-treated with Glucose deficiency]] results in decreased expression of ATP5F1D protein] CTD PMID:25305180 NCBI chr 7:12,426,807...12,432,120
Ensembl chr 7:12,426,809...12,432,130
JBrowse link
G Atp6ap2 ATPase H+ transporting accessory protein 2 increases expression
multiple interactions
EXP Glucose results in increased expression of ATP6AP2 mRNA; Glucose results in increased expression of ATP6AP2 protein
N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide inhibits the reaction [Glucose results in increased expression of ATP6AP2 mRNA]; N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide inhibits the reaction [Glucose results in increased expression of ATP6AP2 protein]
CTD PMID:19861503 NCBI chr  X:11,137,889...11,164,854
Ensembl chr  X:11,136,939...11,164,915
JBrowse link
G Aurka aurora kinase A increases expression ISO Glucose results in increased expression of AURKA mRNA CTD PMID:17178593 NCBI chr 3:170,364,177...170,380,278
Ensembl chr 3:170,364,181...170,378,210
JBrowse link
G Azgp1 alpha-2-glycoprotein 1, zinc-binding affects secretion ISO Glucose deficiency affects the secretion of AZGP1 protein CTD PMID:24802182 NCBI chr12:19,196,565...19,203,094
Ensembl chr12:19,196,611...19,202,647
JBrowse link
G B3gat3 beta-1,3-glucuronyltransferase 3 increases expression
multiple interactions
EXP Glucose results in increased expression of B3GAT3 mRNA
[XDH protein co-treated with Hypoxanthine] inhibits the reaction [Glucose results in increased expression of B3GAT3 mRNA]; IL1B protein inhibits the reaction [Glucose results in increased expression of B3GAT3 mRNA]
CTD PMID:11801247 NCBI chr 1:225,120,061...225,126,579
Ensembl chr 1:225,120,061...225,126,579
JBrowse link
G Bad BCL2-associated agonist of cell death multiple interactions ISO [resveratrol results in increased activity of SIRT1 protein] inhibits the reaction [Glucose results in decreased phosphorylation of and results in decreased activity of BAD protein]; Glucose results in decreased phosphorylation of and results in decreased activity of BAD protein CTD PMID:20370652 NCBI chr 1:222,198,516...222,207,459
Ensembl chr 1:222,198,534...222,207,453
JBrowse link
G Bak1 BCL2-antagonist/killer 1 multiple interactions EXP [[Oxygen deficiency co-treated with Glucose deficiency] results in increased susceptibility to Carvedilol] which results in decreased expression of BAK1 mRNA CTD PMID:29122578 NCBI chr20:5,609,620...5,618,899
Ensembl chr20:5,609,625...5,618,260
JBrowse link
G Bax BCL2 associated X, apoptosis regulator increases expression
affects expression
multiple interactions
ISO
EXP
Glucose results in increased expression of BAX mRNA; Glucose results in increased expression of BAX protein
Glucose affects the expression of BAX protein
3,3',4,5'-tetrahydroxystilbene inhibits the reaction [Glucose results in increased expression of BAX protein]; [Dithionite co-treated with Glucose deficiency] results in increased expression of BAX protein; [Oxygen co-treated with [Oxygen deficiency co-treated with Glucose deficiency]] results in increased expression of BAX protein; [Oxygen deficiency co-treated with Glucose deficiency] results in increased expression of BAX protein; Chloroquine inhibits the reaction [Resveratrol inhibits the reaction [Glucose results in increased expression of BAX protein]]; cinnamic acid inhibits the reaction [Glucose results in increased expression of BAX protein]; dorsomorphin inhibits the reaction [Resveratrol inhibits the reaction [Glucose results in increased expression of BAX protein]]; Metformin inhibits the reaction [Glucose results in increased expression of BAX protein]; naringenin inhibits the reaction [Glucose results in increased expression of BAX mRNA]; naringenin inhibits the reaction [Glucose results in increased expression of BAX protein]; notoginsenoside R1 inhibits the reaction [[Oxygen co-treated with [Oxygen deficiency co-treated with Glucose deficiency]] results in increased expression of BAX protein]; Quercetin affects the reaction [Glucose affects the expression of BAX protein]; Quercetin inhibits the reaction [[Dithionite co-treated with Glucose deficiency] results in increased expression of BAX protein]; Resveratrol inhibits the reaction [Glucose results in increased expression of BAX protein]; sesamin affects the reaction [Glucose affects the expression of BAX protein]; STIM1 protein affects the reaction [Glucose results in increased expression of BAX protein]; trigonelline inhibits the reaction [[Oxygen deficiency co-treated with Glucose deficiency] results in increased expression of BAX protein]
8-dibenzothiophen-4-yl-2-morpholin-4-yl-chromen-4-one promotes the reaction [[Glucose co-treated with Bupivacaine] results in increased expression of BAX protein]; [Glucose co-treated with Bupivacaine] results in increased expression of BAX protein; [Oxygen deficiency co-treated with Glucose deficiency] results in increased expression of BAX; [Oxygen deficiency co-treated with Glucose deficiency] results in increased expression of BAX protein; [Oxygen deficiency co-treated with Glucose deficiency] results in increased expression of BAX protein modified form; Resveratrol inhibits the reaction [[Oxygen deficiency co-treated with Glucose deficiency] results in increased expression of BAX protein]; SIRT7 protein inhibits the reaction [[Oxygen deficiency co-treated with Glucose deficiency] results in increased expression of BAX protein]; U 0126 inhibits the reaction [[Oxygen deficiency co-treated with Glucose deficiency] results in increased expression of BAX protein]
2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [spiraeoside inhibits the reaction [Glucose results in increased expression of BAX protein]]; [Carnosine co-treated with asiatic acid] inhibits the reaction [Glucose results in increased expression of BAX mRNA]; asiatic acid inhibits the reaction [Glucose results in increased expression of BAX mRNA]; Carnosine inhibits the reaction [Glucose results in increased expression of BAX mRNA]; diallyl trisulfide inhibits the reaction [Glucose results in increased expression of BAX protein]; MitoTEMPO inhibits the reaction [Glucose results in increased expression of BAX protein]; NDRG2 protein promotes the reaction [[Oxygen deficiency co-treated with Glucose deficiency] results in increased expression of BAX protein]; Resveratrol inhibits the reaction [Glucose results in increased expression of BAX protein]; salvianolic acid inhibits the reaction [Glucose results in increased expression of BAX protein]; spiraeoside inhibits the reaction [Glucose results in increased expression of BAX protein]
CTD PMID:21803128 PMID:22524206 PMID:23192364 PMID:23451161 PMID:24218232 PMID:24682241 PMID:25238743 PMID:25305180 PMID:26054749 PMID:27234048 PMID:28675767 PMID:28713934 PMID:30144576 PMID:30431688 PMID:30802477 PMID:31115753 PMID:31323227 PMID:31672611 PMID:31935362 PMID:32602595 NCBI chr 1:101,451,801...101,457,207
Ensembl chr 1:101,451,802...101,457,207
JBrowse link
G Bbc3 Bcl-2 binding component 3 multiple interactions ISO [Palmitic Acid co-treated with Glucose] results in increased expression of BBC3 mRNA; SIRT1 protein mutant form inhibits the reaction [[Palmitic Acid co-treated with Glucose] results in increased expression of BBC3 mRNA]
[Oxygen deficiency co-treated with Glucose deficiency] results in increased expression of BBC3 protein modified form; SIRT7 protein inhibits the reaction [[Oxygen deficiency co-treated with Glucose deficiency] results in increased expression of BBC3 protein]
CTD PMID:24451382 PMID:28675767 NCBI chr 1:78,261,491...78,267,802 JBrowse link
G Bcl2 BCL2, apoptosis regulator decreases expression
multiple interactions
affects expression
ISO
EXP
Glucose results in decreased expression of BCL2 mRNA; Glucose results in decreased expression of BCL2 protein
8-dibenzothiophen-4-yl-2-morpholin-4-yl-chromen-4-one promotes the reaction [[Glucose co-treated with Bupivacaine] results in decreased expression of BCL2 protein]; [Glucose co-treated with Bupivacaine] results in decreased expression of BCL2 protein; [Oxygen deficiency co-treated with Glucose deficiency] results in decreased expression of BCL2 mRNA; [Oxygen deficiency co-treated with Glucose deficiency] results in decreased expression of BCL2 protein; [Oxygen deficiency co-treated with Glucose deficiency] results in increased expression of BCL2 mRNA; cyclopamine inhibits the reaction [[Oxygen deficiency co-treated with Glucose deficiency] results in increased expression of BCL2 mRNA]; cyclopamine inhibits the reaction [polydatin promotes the reaction [[Oxygen deficiency co-treated with Glucose deficiency] results in increased expression of BCL2 mRNA]]; MIR210 mRNA inhibits the reaction [[Oxygen deficiency co-treated with Glucose deficiency] results in decreased expression of BCL2 mRNA]; polydatin promotes the reaction [[Oxygen deficiency co-treated with Glucose deficiency] results in increased expression of BCL2 mRNA]; Resveratrol inhibits the reaction [[Oxygen deficiency co-treated with Glucose deficiency] results in decreased expression of BCL2 protein]; U 0126 inhibits the reaction [[Oxygen deficiency co-treated with Glucose deficiency] results in decreased expression of BCL2 protein]
2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [spiraeoside inhibits the reaction [Glucose results in decreased expression of BCL2 protein]]; [Resveratrol co-treated with Glucose] results in increased expression of BCL2 protein; asiatic acid inhibits the reaction [Glucose results in decreased expression of BCL2 mRNA]; asiatic acid promotes the reaction [Carnosine inhibits the reaction [Glucose results in decreased expression of BCL2 mRNA]]; Berberine inhibits the reaction [Glucose results in decreased expression of BCL2 protein]; Carnosine inhibits the reaction [Glucose results in decreased expression of BCL2 mRNA]; Carnosine promotes the reaction [asiatic acid inhibits the reaction [Glucose results in decreased expression of BCL2 mRNA]]; Catechin inhibits the reaction [Glucose results in increased degradation of and results in decreased expression of BCL2 protein]; diallyl trisulfide inhibits the reaction [Glucose results in decreased expression of BCL2 protein]; epigallocatechin gallate inhibits the reaction [Glucose results in increased degradation of and results in decreased expression of BCL2 protein]; Gliclazide inhibits the reaction [Glucose results in decreased expression of BCL2 protein]; Glucose inhibits the reaction [[KCNMA1 protein binds to KCNMB1 protein] which results in decreased expression of BCL2 protein]; Glucose results in increased degradation of and results in decreased expression of BCL2 protein; Luteolin inhibits the reaction [Glucose results in increased degradation of and results in decreased expression of BCL2 protein]; manganese(III)-tetrakis(4-benzoic acid)porphyrin inhibits the reaction [Glucose results in decreased expression of BCL2 protein]; MitoTEMPO inhibits the reaction [Glucose results in decreased expression of BCL2 protein]; NS 1619 inhibits the reaction [Glucose inhibits the reaction [[KCNMA1 protein binds to KCNMB1 protein] which results in decreased expression of BCL2 protein]]; Quercetin inhibits the reaction [Glucose results in increased degradation of and results in decreased expression of BCL2 protein]; Rutin inhibits the reaction [Glucose results in increased degradation of and results in decreased expression of BCL2 protein]; salvianolic acid inhibits the reaction [Glucose results in decreased expression of BCL2 protein]; spiraeoside inhibits the reaction [Glucose results in decreased expression of BCL2 protein]; Tamoxifen inhibits the reaction [Glucose inhibits the reaction [[KCNMA1 protein binds to KCNMB1 protein] which results in decreased expression of BCL2 protein]]
15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid inhibits the reaction [notoginsenoside R1 inhibits the reaction [[Oxygen co-treated with [Oxygen deficiency co-treated with Glucose deficiency]] results in decreased expression of BCL2 protein]]; 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [Quercetin inhibits the reaction [[Dithionite co-treated with Glucose deficiency] results in decreased expression of BCL2 protein]]; 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one promotes the reaction [[Dithionite co-treated with Glucose deficiency] results in decreased expression of BCL2 protein]; 3,3',4,5'-tetrahydroxystilbene inhibits the reaction [Glucose results in decreased expression of BCL2 protein]; [Dithionite co-treated with Glucose deficiency] results in decreased expression of BCL2 protein; [Linoleic Acid co-treated with Glucose] affects the reaction [Azoxymethane affects the expression of BCL2 protein]; [Oxygen co-treated with [Oxygen deficiency co-treated with Glucose deficiency]] results in decreased expression of BCL2 protein; [Oxygen deficiency co-treated with Glucose deficiency] affects the expression of BCL2 mRNA; [Oxygen deficiency co-treated with Glucose deficiency] results in decreased expression of BCL2 protein; Chloroquine inhibits the reaction [Resveratrol inhibits the reaction [Glucose results in decreased expression of BCL2 protein]]; cinnamic acid inhibits the reaction [Glucose results in decreased expression of BCL2 protein]; dorsomorphin inhibits the reaction [Resveratrol inhibits the reaction [Glucose results in decreased expression of BCL2 protein]]; Metformin inhibits the reaction [Glucose results in decreased expression of BCL2 protein]; naringenin inhibits the reaction [Glucose results in decreased expression of BCL2 mRNA]; naringenin inhibits the reaction [Glucose results in decreased expression of BCL2 protein]; notoginsenoside R1 inhibits the reaction [[Oxygen co-treated with [Oxygen deficiency co-treated with Glucose deficiency]] results in decreased expression of BCL2 protein]; Quercetin affects the reaction [Glucose affects the expression of BCL2 protein]; Quercetin inhibits the reaction [[Dithionite co-treated with Glucose deficiency] results in decreased expression of BCL2 protein]; Resveratrol inhibits the reaction [Glucose results in decreased expression of BCL2 protein]; sesamin affects the reaction [Glucose affects the expression of BCL2 protein]; STIM1 protein affects the reaction [Glucose results in decreased expression of BCL2 protein]; trigonelline inhibits the reaction [[Oxygen deficiency co-treated with Glucose deficiency] results in decreased expression of BCL2 protein]
Glucose affects the expression of BCL2 mRNA; Glucose affects the expression of BCL2 protein
CTD PMID:18088078 PMID:19557821 PMID:21413024 PMID:21803128 PMID:21818840 PMID:22467055 PMID:22524206 PMID:23108914 PMID:23192364 PMID:23637816 PMID:23954465 PMID:24218232 PMID:24349266 PMID:24682241 PMID:25305180 PMID:26054749 PMID:27234048 PMID:27481074 PMID:28713934 PMID:30144576 PMID:30431688 PMID:30802477 PMID:31115753 PMID:31323227 PMID:31672611 PMID:31935362 PMID:32602595 NCBI chr13:26,605,426...26,769,374
Ensembl chr13:26,605,426...26,769,374
JBrowse link
G Bcl2l1 Bcl2-like 1 multiple interactions EXP BCL2L1 protein results in decreased susceptibility to [Oxygen deficiency co-treated with Glucose deficiency] CTD PMID:21124846 NCBI chr 3:148,259,594...148,314,191
Ensembl chr 3:148,259,596...148,313,810
JBrowse link
G Bcl2l11 BCL2 like 11 multiple interactions
increases expression
EXP 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [resveratrol inhibits the reaction [Glucose results in increased expression of BCL2L11 protein]]; resveratrol inhibits the reaction [Glucose results in increased expression of BCL2L11 protein] CTD PMID:25471227 NCBI chr 3:120,726,906...120,764,192
Ensembl chr 3:120,726,906...120,764,192
JBrowse link
G Bdkrb1 bradykinin receptor B1 increases expression
multiple interactions
EXP Glucose results in increased expression of BDKRB1 protein
argan oil inhibits the reaction [Glucose results in increased expression of BDKRB1 protein]; Corn Oil inhibits the reaction [Glucose results in increased expression of BDKRB1 protein]
CTD PMID:29165388 NCBI chr 6:129,437,423...129,441,553
Ensembl chr 6:129,438,158...129,440,574
JBrowse link
G Becn1 beclin 1 multiple interactions
decreases expression
EXP
ISO
[Glucose deficiency co-treated with Galactose co-treated with Pyruvic Acid] inhibits the reaction [Doxorubicin results in decreased expression of BECN1 protein]; [Resveratrol co-treated with Glucose] results in increased expression of BECN1 protein
Glucose results in decreased expression of BECN1 protein
HU 308 inhibits the reaction [Glucose results in decreased expression of BECN1 protein]
CTD PMID:25997894 PMID:28713934 PMID:30459625 NCBI chr10:89,209,944...89,225,297
Ensembl chr10:89,209,940...89,225,297
JBrowse link
G Bmp2 bone morphogenetic protein 2 decreases expression
multiple interactions
ISO Glucose results in decreased expression of BMP2 mRNA
cobaltiprotoporphyrin inhibits the reaction [Glucose results in decreased expression of BMP2 mRNA]; tin mesoporphyrin promotes the reaction [Glucose results in decreased expression of BMP2 mRNA]
CTD PMID:19924377 NCBI chr 3:126,335,963...126,346,771
Ensembl chr 3:126,335,863...126,346,318
JBrowse link
G C1qtnf3 C1q and TNF related 3 decreases expression ISO Glucose results in decreased expression of C1QTNF3 mRNA CTD PMID:31525975 NCBI chr 2:60,920,160...60,942,586
Ensembl chr 2:60,920,257...60,942,500
JBrowse link
G C1r complement C1r decreases secretion ISO Glucose deficiency results in decreased secretion of C1R protein CTD PMID:24802182 NCBI chr 4:157,126,060...157,136,825
Ensembl chr 4:157,125,998...157,136,829
JBrowse link
G C1s complement C1s affects secretion ISO Glucose deficiency affects the secretion of C1S protein CTD PMID:24802182 NCBI chr 4:157,143,592...157,155,592
Ensembl chr 4:157,143,592...157,155,609
JBrowse link
G C3 complement C3 increases expression
multiple interactions
ISO Glucose results in increased expression of C3 mRNA
[Oxygen deficiency co-treated with Glucose deficiency] results in increased expression of C3 mRNA
CTD PMID:17178593 PMID:23199288 NCBI chr 9:9,721,137...9,747,084
Ensembl chr 9:9,721,105...9,747,167
JBrowse link
G Calca calcitonin-related polypeptide alpha increases expression ISO Glucose results in increased expression of CALCA mRNA CTD PMID:31655124 NCBI chr 1:184,184,018...184,188,922
Ensembl chr 1:184,184,020...184,188,911
JBrowse link
G Calm2 calmodulin 2 multiple interactions EXP CALM2 protein results in decreased susceptibility to [Oxygen deficiency co-treated with Glucose deficiency] CTD PMID:21124846 NCBI chr 6:11,067,675...11,080,078
Ensembl chr15:65,506,874...65,507,968
JBrowse link
G Calr calreticulin decreases expression ISO Glucose results in decreased expression of CALR mRNA CTD PMID:17178593 NCBI chr19:25,956,771...25,961,666
Ensembl chr19:25,956,771...25,961,666
JBrowse link
G Calu calumenin decreases secretion ISO Glucose deficiency results in decreased secretion of CALU protein CTD PMID:24802182 NCBI chr 4:56,625,611...56,653,112
Ensembl chr 4:56,625,561...56,653,111
JBrowse link
G Caly calcyon neuron-specific vesicular protein multiple interactions EXP CALY protein results in decreased susceptibility to [Oxygen deficiency co-treated with Glucose deficiency] CTD PMID:21124846 NCBI chr 1:212,537,851...212,549,040
Ensembl chr 1:212,537,848...212,549,477
JBrowse link
G Canx calnexin decreases expression ISO Glucose results in decreased expression of CANX mRNA CTD PMID:17178593 NCBI chr10:35,800,942...35,833,939
Ensembl chr10:35,800,942...35,833,861
JBrowse link
G Capn1 calpain 1 multiple interactions
increases expression
EXP
ISO
2-(4-methoxyphenyl)ethyl-2-acetamido-2-deoxyglucopyranoside inhibits the reaction [[Oxygen co-treated with Glucose deficiency] results in increased expression of CAPN1 protein]; [Oxygen co-treated with Glucose deficiency] results in increased expression of CAPN1 protein
Furans analog inhibits the reaction [Glucose results in increased expression of CAPN1 protein]
CTD PMID:24726522 PMID:28911973 NCBI chr 1:221,346,081...221,370,965
Ensembl chr 1:221,346,066...221,370,322
JBrowse link
G Casp1 caspase 1 multiple interactions
increases cleavage
increases expression
increases activity
ISO
EXP
Acetylcysteine inhibits the reaction [Glucose results in increased cleavage of CASP1 protein]; FOXO3 protein promotes the reaction [Glucose results in increased cleavage of and results in increased activity of CASP1 protein]; Glucose results in increased cleavage of and results in increased activity of CASP1 protein
Glucose results in increased expression of CASP1 protein
Allopurinol inhibits the reaction [Glucose results in increased expression of CASP1 protein]; L 709049 analog inhibits the reaction [Glucose results in increased expression of CASP1 protein]; Quercetin inhibits the reaction [Glucose results in increased expression of CASP1 protein]; rhodioloside inhibits the reaction [Glucose results in increased expression of CASP1 protein]; Suramin inhibits the reaction [Glucose results in increased activity of CASP1 protein]; TXNIP mRNA promotes the reaction [Glucose results in increased expression of CASP1 protein]
Allopurinol inhibits the reaction [Glucose results in increased expression of CASP1 protein]; L 709049 analog inhibits the reaction [Glucose results in increased expression of CASP1 protein]; Quercetin inhibits the reaction [Glucose results in increased expression of CASP1 protein]; TXNIP mRNA promotes the reaction [Glucose results in increased expression of CASP1 protein]
Glucose results in increased activity of CASP1 mRNA; Glucose results in increased activity of CASP1 protein
CTD PMID:20370652 PMID:21832250 PMID:23647015 PMID:27783111 PMID:29031534 NCBI chr 8:2,605,743...2,614,637
Ensembl chr 8:2,604,962...2,614,631
JBrowse link
G Casp12 caspase 12 multiple interactions
increases cleavage
ISO TRPM7 protein affects the reaction [Glucose results in increased cleavage of CASP12 protein]; waixenicin A inhibits the reaction [Glucose results in increased cleavage of CASP12 protein] CTD PMID:30076216 NCBI chr 8:2,658,892...2,686,160
Ensembl chr 8:2,659,865...2,686,160
JBrowse link
G Casp3 caspase 3 multiple interactions
decreases expression
increases cleavage
increases expression
increases activity
ISO
EXP
[Carnosine co-treated with asiatic acid] inhibits the reaction [Glucose results in increased activity of CASP3 protein]; [Glucose deficiency co-treated with Acetylcysteine] results in increased activity of CASP3 protein; [Glucose deficiency co-treated with CAT] results in increased activity of CASP3 protein; [Glucose deficiency co-treated with Tetradecanoylphorbol Acetate] results in increased activity of CASP3 protein; [Palmitic Acid co-treated with Glucose] results in increased cleavage of CASP3 protein; asiatic acid inhibits the reaction [Glucose results in increased activity of CASP3 protein]; Carnosine inhibits the reaction [Glucose results in increased activity of CASP3 protein]; diallyl trisulfide inhibits the reaction [Glucose results in increased activity of CASP3 protein]; Gliclazide inhibits the reaction [Glucose results in increased expression of CASP3 protein]; manganese(III)-tetrakis(4-benzoic acid)porphyrin inhibits the reaction [Glucose results in increased expression of CASP3 protein]; MitoTEMPO inhibits the reaction [Glucose results in increased activity of CASP3 protein]; Rosiglitazone inhibits the reaction [Glucose results in increased activity of CASP3 protein]; salvianolic acid inhibits the reaction [Glucose results in increased cleavage of CASP3 protein]; SIRT1 protein inhibits the reaction [[Palmitic Acid co-treated with Glucose] results in increased cleavage of CASP3 protein]
Glucose results in decreased expression of CASP3 mRNA
Glucose results in increased expression of CASP3 mRNA; Glucose results in increased expression of CASP3 protein modified form
15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid inhibits the reaction [notoginsenoside R1 inhibits the reaction [[Oxygen co-treated with [Oxygen deficiency co-treated with Glucose deficiency]] results in increased cleavage of CASP3 protein]]; 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [trigonelline inhibits the reaction [[Oxygen deficiency co-treated with Glucose deficiency] results in increased activity of CASP3 protein]]; [Dithionite co-treated with Glucose deficiency] results in increased cleavage of CASP3 protein; [Glucose deficiency co-treated with Galactose co-treated with Pyruvic Acid] inhibits the reaction [Doxorubicin results in increased activity of CASP3 protein]; [Oxygen co-treated with [Oxygen deficiency co-treated with Glucose deficiency]] results in increased activity of CASP3 protein; [Oxygen co-treated with [Oxygen deficiency co-treated with Glucose deficiency]] results in increased cleavage of CASP3 protein; [Oxygen deficiency co-treated with Glucose deficiency] affects the expression of and affects the activity of CASP3 protein; [Oxygen deficiency co-treated with Glucose deficiency] results in increased activity of CASP3 protein; [Oxygen deficiency co-treated with Glucose deficiency] results in increased cleavage of CASP3 protein; [Oxygen deficiency co-treated with Glucose deficiency] results in increased expression of CASP3 protein; [Oxygen deficiency co-treated with Glucose deficiency] results in increased expression of CASP3 protein modified form; Acetylcysteine inhibits the reaction [Glucose results in increased activity of CASP3]; Antigen-Antibody Complex inhibits the reaction [[Oxygen deficiency co-treated with Glucose deficiency] results in increased activity of CASP3 protein]; cinnamic acid inhibits the reaction [Glucose results in increased activity of CASP3 protein]; cobaltiprotoporphyrin inhibits the reaction [Glucose results in increased cleavage of CASP3 protein]; diallyl trisulfide inhibits the reaction [[Oxygen deficiency co-treated with Glucose deficiency] results in increased expression of CASP3 protein modified form]; diallyl trisulfide inhibits the reaction [Glucose results in increased cleavage of CASP3 protein]; Glucose results in increased expression of and results in increased cleavage of CASP3 protein; GSK3B protein inhibits the reaction [MIR135A mRNA inhibits the reaction [[Oxygen deficiency co-treated with Glucose deficiency] results in increased activity of CASP3 protein]]; HMOX1 protein affects the reaction [Propofol inhibits the reaction [Glucose results in increased cleavage of CASP3 protein]]; HMOX1 protein promotes the reaction [diallyl trisulfide inhibits the reaction [[Oxygen deficiency co-treated with Glucose deficiency] results in increased expression of CASP3 protein modified form]]; Metformin inhibits the reaction [Glucose results in increased activity of CASP3 protein]; MIR135A mRNA inhibits the reaction [[Oxygen deficiency co-treated with Glucose deficiency] results in increased activity of CASP3 protein]; naringenin inhibits the reaction [Glucose results in increased activity of CASP3 protein]; naringenin inhibits the reaction [Glucose results in increased expression of and results in increased cleavage of CASP3 protein]; naringenin inhibits the reaction [Glucose results in increased expression of CASP3 mRNA]; NFE2L2 mutant form inhibits the reaction [diallyl trisulfide inhibits the reaction [Glucose results in increased cleavage of CASP3 protein]]; NFE2L2 protein mutant form affects the reaction [plumbagin inhibits the reaction [[Oxygen deficiency co-treated with Glucose deficiency] results in increased activity of CASP3 protein]]; NFE2L2 protein promotes the reaction [diallyl trisulfide inhibits the reaction [[Oxygen deficiency co-treated with Glucose deficiency] results in increased expression of CASP3 protein modified form]]; notoginsenoside R1 inhibits the reaction [[Oxygen co-treated with [Oxygen deficiency co-treated with Glucose deficiency]] results in increased activity of CASP3 protein]; notoginsenoside R1 inhibits the reaction [[Oxygen co-treated with [Oxygen deficiency co-treated with Glucose deficiency]] results in increased cleavage of CASP3 protein]; plumbagin inhibits the reaction [[Oxygen deficiency co-treated with Glucose deficiency] results in increased activity of CASP3 protein]; Propofol inhibits the reaction [Glucose results in increased cleavage of CASP3 protein]; Quercetin inhibits the reaction [[Dithionite co-treated with Glucose deficiency] results in increased expression of CASP3 protein]; Quercetin inhibits the reaction [[Oxygen deficiency co-treated with Glucose deficiency] results in increased expression of CASP3 protein]; Quercetin inhibits the reaction [Glucose results in increased cleavage of CASP3 protein]; Quercetin inhibits the reaction [Glucose results in increased expression of CASP3 mRNA]; Quercetin inhibits the reaction [Glucose results in increased expression of CASP3 protein modified form]; sesamin inhibits the reaction [Glucose results in increased cleavage of CASP3 protein]; Simvastatin inhibits the reaction [Glucose results in increased cleavage of CASP3 protein]; STAT3 protein affects the reaction [Propofol inhibits the reaction [Glucose results in increased cleavage of CASP3 protein]]; STIM1 protein affects the reaction [Glucose results in increased cleavage of CASP3 protein]; trigonelline inhibits the reaction [[Oxygen deficiency co-treated with Glucose deficiency] results in increased activity of CASP3 protein]; WDR35 protein affects the reaction [Glucose results in increased activity of CASP3 protein]; Y 27632 inhibits the reaction [[Oxygen co-treated with [Oxygen deficiency co-treated with Glucose deficiency]] results in increased cleavage of CASP3 protein]
Glucose results in increased activity of CASP3; Glucose results in increased activity of CASP3 protein
[Glucose deficiency co-treated with Simvastatin] results in increased cleavage of CASP3 protein; [Oxygen deficiency co-treated with Glucose deficiency] results in increased activity of CASP3 protein; [Oxygen deficiency co-treated with Glucose deficiency] results in increased cleavage of CASP3 protein; FOXO3 protein promotes the reaction [Glucose results in increased cleavage of and results in increased activity of CASP3 protein]; Glucose deficiency inhibits the reaction [Arsenic Trioxide results in increased expression of CASP3 protein modified form]; Glucose results in increased cleavage of and results in increased activity of CASP3 protein; INO 1001 inhibits the reaction [Glucose results in increased activity of CASP3 protein]; MIR144 mRNA promotes the reaction [[Oxygen deficiency co-treated with Glucose deficiency] results in increased activity of CASP3 protein]; MIR322 affects the reaction [Glucose results in increased cleavage of CASP3 protein]; N-(oxo-5,6-dihydrophenanthridin-2-yl)-N,N-dimethylacetamide hydrochloride inhibits the reaction [Glucose results in increased activity of CASP3 protein]; Resveratrol inhibits the reaction [[Oxygen deficiency co-treated with Glucose deficiency] results in increased activity of CASP3 protein]; Resveratrol inhibits the reaction [[Oxygen deficiency co-treated with Glucose deficiency] results in increased cleavage of CASP3 protein]; SIRT7 protein inhibits the reaction [[Oxygen deficiency co-treated with Glucose deficiency] results in increased activity of CASP3 protein]; TRAF3 affects the reaction [Glucose results in increased cleavage of CASP3 protein]; TRPM7 protein affects the reaction [Glucose results in increased cleavage of CASP3 protein]; U 0126 inhibits the reaction [[Oxygen deficiency co-treated with Glucose deficiency] results in increased cleavage of CASP3 protein]; VDAC1 protein inhibits the reaction [Resveratrol inhibits the reaction [[Oxygen deficiency co-treated with Glucose deficiency] results in increased activity of CASP3 protein]]; VDAC1 protein promotes the reaction [[Oxygen deficiency co-treated with Glucose deficiency] results in increased activity of CASP3 protein]; waixenicin A inhibits the reaction [Glucose results in increased cleavage of CASP3 protein]; zinc protoporphyrin inhibits the reaction [[Glucose deficiency co-treated with Simvastatin] results in increased cleavage of CASP3 protein]
CTD PMID:15322300 PMID:16135072 PMID:17065336 PMID:17309078 PMID:17928392 PMID:18004065 PMID:18088078 PMID:18791325 PMID:18973755 PMID:19767878 PMID:19892008 PMID:20028456 PMID:20224876 PMID:20370652 PMID:21803128 PMID:22524206 PMID:23192364 PMID:23453443 PMID:23637816 PMID:23758074 PMID:23770986 PMID:24349266 PMID:24451382 PMID:24682241 PMID:24720662 PMID:24810525 PMID:25238743 PMID:25305180 PMID:25488258 PMID:25516495 PMID:25896937 PMID:25997894 PMID:27234048 PMID:28675767 PMID:29095437 PMID:29457851 PMID:29702141 PMID:29719095 PMID:30076216 PMID:30144576 PMID:30431688 PMID:30802477 PMID:31115753 PMID:31655124 PMID:31935362 NCBI chr16:48,845,011...48,863,249
Ensembl chr16:48,845,012...48,863,204
JBrowse link
G Casp8 caspase 8 increases activity
multiple interactions
ISO
EXP
Glucose results in increased activity of CASP8 protein
Acetylcysteine inhibits the reaction [Glucose results in increased activity of CASP8]
CTD PMID:18791325 PMID:18973755 NCBI chr 9:65,614,142...65,662,624
Ensembl chr 9:65,614,142...65,662,106
JBrowse link
G Casp9 caspase 9 multiple interactions
increases cleavage
increases expression
increases activity
ISO
EXP
[Glucose deficiency co-treated with Acetylcysteine] results in increased activity of CASP9 protein; [Glucose deficiency co-treated with CAT] results in increased activity of CASP9 protein; [Glucose deficiency co-treated with Tetradecanoylphorbol Acetate] results in increased activity of CASP9 protein; salvianolic acid inhibits the reaction [Glucose results in increased cleavage of CASP9 protein]
Glucose results in increased expression of CASP9 mRNA
[Glucose deficiency co-treated with Galactose co-treated with Pyruvic Acid] inhibits the reaction [Doxorubicin results in increased activity of CASP9 protein]; Acetylcysteine inhibits the reaction [Glucose results in increased activity of CASP9]; Glucose results in increased expression of and results in increased cleavage of CASP9 protein; naringenin inhibits the reaction [Glucose results in increased expression of and results in increased cleavage of CASP9 protein]; naringenin inhibits the reaction [Glucose results in increased expression of CASP9 mRNA]
CTD PMID:17309078 PMID:18791325 PMID:23192364 PMID:25997894 PMID:30431688 NCBI chr 5:160,356,211...160,373,774
Ensembl chr 5:160,355,833...160,373,778
JBrowse link
G Cat catalase multiple interactions
increases activity
decreases activity
increases expression
decreases expression
ISO
EXP
2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [spiraeoside inhibits the reaction [Glucose results in increased activity of CAT protein]]; [Glucose deficiency co-treated with CAT] affects the localization of ENDOG protein; [Glucose deficiency co-treated with CAT] results in increased activity of CASP3 protein; [Glucose deficiency co-treated with CAT] results in increased activity of CASP9 protein; [Glucose deficiency co-treated with CAT] results in increased cleavage of PARP1 protein; CAT inhibits the reaction [Glucose deficiency affects the folding of SOD2 protein]; CAT inhibits the reaction [Glucose deficiency results in increased activity of MAPK1 protein]; CAT inhibits the reaction [Glucose deficiency results in increased activity of MAPK14 protein]; CAT inhibits the reaction [Glucose deficiency results in increased activity of MAPK3 protein]; CAT inhibits the reaction [Glucose deficiency results in increased degradation of SOD1 protein]; CAT protein inhibits the reaction [Glucose promotes the reaction [EDN1 protein results in increased chemical synthesis of Inositol 1,4,5-Trisphosphate]]; cyclopamine inhibits the reaction [SHH protein inhibits the reaction [[Oxygen deficiency co-treated with Glucose deficiency] results in decreased activity of CAT protein]]; Furans analog inhibits the reaction [Glucose results in decreased activity of CAT protein]; SHH protein inhibits the reaction [[Oxygen deficiency co-treated with Glucose deficiency] results in decreased activity of CAT protein]; SIRT3 protein inhibits the reaction [Glucose results in increased expression of CAT protein]; spiraeoside inhibits the reaction [Glucose results in increased activity of CAT protein]
[Oxygen deficiency co-treated with Glucose deficiency] results in decreased activity of CAT protein; cyclopamine inhibits the reaction [polydatin inhibits the reaction [[Oxygen deficiency co-treated with Glucose deficiency] results in decreased activity of CAT protein]]; cyclopamine promotes the reaction [[Oxygen deficiency co-treated with Glucose deficiency] results in decreased activity of CAT protein]; polydatin inhibits the reaction [[Oxygen deficiency co-treated with Glucose deficiency] results in decreased activity of CAT protein]
Glucose deficiency results in increased expression of CAT protein; Glucose results in increased expression of CAT protein
[Oxygen deficiency co-treated with Glucose deficiency co-treated with Oxygen] results in decreased activity of CAT protein; CAT protein inhibits the reaction [Glucose results in increased expression of AGT mRNA]; CAT protein inhibits the reaction [Glucose results in increased expression of AGT protein]; CAT protein inhibits the reaction [Glucose results in increased expression of GNA11 protein]; CAT protein inhibits the reaction [Glucose results in increased expression of GNAQ protein]; CAT protein inhibits the reaction [Glucose results in increased expression of PLCB1 protein]; CAT protein inhibits the reaction [Glucose results in increased expression of PLCB2 protein]; naringenin inhibits the reaction [Glucose results in decreased activity of CAT protein]; Resveratrol inhibits the reaction [[Oxygen deficiency co-treated with Glucose deficiency co-treated with Oxygen] results in decreased activity of CAT protein]; Resveratrol inhibits the reaction [Glucose results in decreased activity of CAT protein]
Glucose results in decreased expression of CAT mRNA
CTD PMID:12130563 PMID:17309078 PMID:20691780 PMID:21818840 PMID:23192364 PMID:23421680 PMID:23494737 PMID:26054749 PMID:27481074 PMID:28027979 PMID:28911973 PMID:32602595 NCBI chr 3:93,379,872...93,412,058
Ensembl chr 3:93,379,874...93,412,058
JBrowse link
G Cav1 caveolin 1 decreases expression
multiple interactions
ISO Glucose results in decreased expression of CAV1 mRNA; Glucose results in decreased expression of CAV1 protein
EGF protein inhibits the reaction [Glucose results in decreased expression of CAV1 mRNA]; Simvastatin inhibits the reaction [Glucose results in decreased expression of CAV1 mRNA]
CTD PMID:19816600 PMID:31655124 NCBI chr 4:44,597,123...44,630,206
Ensembl chr 4:44,597,123...44,630,200
JBrowse link
G Cbr3 carbonyl reductase 3 increases expression ISO Glucose results in increased expression of CBR3 mRNA CTD PMID:17178593 NCBI chr11:33,909,417...33,917,674
Ensembl chr11:33,909,439...33,917,674
JBrowse link
G Cbs cystathionine beta synthase increases expression ISO Glucose results in increased expression of CBS mRNA CTD PMID:17178593 NCBI chr20:10,361,987...10,386,663
Ensembl chr20:10,361,988...10,386,751
JBrowse link
G Ccl2 C-C motif chemokine ligand 2 increases expression
multiple interactions
increases secretion
ISO
EXP
Glucose results in increased expression of CCL2 mRNA; Glucose results in increased expression of CCL2 protein
2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Glucose results in increased expression of CCL2 mRNA]; 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Glucose results in increased expression of CCL2 protein]; [Glucose co-treated with fatostatin] results in increased expression of CCL2 mRNA; [Resveratrol affects the localization of RELA protein] inhibits the reaction [Glucose results in increased expression of CCL2 mRNA]; [Resveratrol affects the localization of RELA protein] inhibits the reaction [Glucose results in increased expression of CCL2 protein]; [Valsartan co-treated with Simvastatin] inhibits the reaction [Glucose promotes the reaction [AGT protein results in increased expression of CCL2 mRNA]]; aspalathin inhibits the reaction [Glucose results in increased expression of CCL2 mRNA]; aspalathin inhibits the reaction [Glucose results in increased expression of CCL2 protein]; Aspirin inhibits the reaction [Glucose results in increased expression of CCL2 mRNA]; Aspirin inhibits the reaction [Glucose results in increased expression of CCL2 protein]; Aspirin inhibits the reaction [Glucose results in increased secretion of CCL2 protein]; CCL2 mRNA affects the reaction [Glucose results in increased expression of CCN2 protein]; chromic chloride inhibits the reaction [Glucose results in increased secretion of CCL2 protein]; chromium nicotinic acid complex inhibits the reaction [Glucose results in increased secretion of CCL2 protein]; Clofibrate inhibits the reaction [Glucose results in increased expression of CCL2 mRNA]; Clofibrate inhibits the reaction [Glucose results in increased expression of CCL2 protein]; Clofibrate inhibits the reaction [Glucose results in increased secretion of CCL2 protein]; diphenyleneiodonium inhibits the reaction [Glucose results in increased expression of CCL2 mRNA]; diphenyleneiodonium inhibits the reaction [Glucose results in increased secretion of CCL2 protein]; Fenofibrate inhibits the reaction [Glucose results in increased expression of CCL2 mRNA]; Fenofibrate inhibits the reaction [Glucose results in increased expression of CCL2 protein]; Fenofibrate inhibits the reaction [Glucose results in increased secretion of CCL2 protein]; Glucose inhibits the reaction [Fructose results in increased secretion of CCL2 protein]; Glucose promotes the reaction [AGT protein results in increased expression of CCL2 mRNA]; HTS 466284 inhibits the reaction [Glucose results in increased expression of CCL2 mRNA]; isoangustone A inhibits the reaction [Glucose results in increased expression of CCL2 mRNA]; manganese chloride inhibits the reaction [Glucose results in increased secretion of CCL2 protein]; nothofagin inhibits the reaction [Glucose results in increased expression of CCL2 mRNA]; nothofagin inhibits the reaction [Glucose results in increased expression of CCL2 protein]; picolinic acid inhibits the reaction [Glucose results in increased secretion of CCL2 protein]; psicose inhibits the reaction [Glucose results in increased expression of CCL2 mRNA]; psicose inhibits the reaction [Glucose results in increased expression of CCL2 protein]; pyrrolidine dithiocarbamic acid inhibits the reaction [Glucose results in increased expression of CCL2 mRNA]; pyrrolidine dithiocarbamic acid inhibits the reaction [Glucose results in increased secretion of CCL2 protein]; Quercetin inhibits the reaction [Glucose results in increased expression of MCP1 mRNA]; Resveratrol inhibits the reaction [Glucose results in increased expression of CCL2 mRNA]; Resveratrol inhibits the reaction [Glucose results in increased expression of CCL2 protein]; SB 203580 inhibits the reaction [Glucose results in increased expression of CCL2 mRNA]; SB 203580 inhibits the reaction [Glucose results in increased expression of CCL2 protein]; Selenium inhibits the reaction [Glucose results in increased expression of CCL2 mRNA]; Tosylphenylalanyl Chloromethyl Ketone inhibits the reaction [Glucose results in increased expression of CCL2 mRNA]; Tosylphenylalanyl Chloromethyl Ketone inhibits the reaction [Glucose results in increased secretion of CCL2 protein]; Valsartan inhibits the reaction [Glucose promotes the reaction [AGT protein results in increased expression of CCL2 mRNA]]
Glucose results in increased expression of CCL2 mRNA; Glucose results in increased expression of CCL2 protein; Glucose results in increased expression of MCP1 mRNA
duanbanhuain A inhibits the reaction [Glucose results in increased secretion of CCL2 protein]; duanbanhuain B inhibits the reaction [Glucose results in increased secretion of CCL2 protein]
CTD PMID:16143069 PMID:16600694 PMID:17178593 PMID:17607302 PMID:17655880 PMID:17665966 PMID:19132243 PMID:19158351 PMID:19225232 PMID:20542118 PMID:21367880 PMID:22036992 PMID:23329836 PMID:24436987 PMID:24513509 PMID:25338943 PMID:29420703 NCBI chr10:69,412,065...69,413,863
Ensembl chr10:69,412,017...69,413,870
JBrowse link
G Ccl5 C-C motif chemokine ligand 5 increases expression ISO Glucose results in increased expression of CCL5 mRNA CTD PMID:17178593 PMID:31655124 NCBI chr10:70,739,764...70,744,303
Ensembl chr10:70,739,800...70,744,315
JBrowse link
G Ccn1 cellular communication network factor 1 increases expression ISO Glucose results in increased expression of CCN1 mRNA CTD PMID:17178593 NCBI chr 2:251,529,354...251,532,312
Ensembl chr 2:251,529,354...251,532,312
JBrowse link
G Ccn2 cellular communication network factor 2 multiple interactions
increases expression
ISO
EXP
2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Glucose results in increased expression of CCN2 protein]; bisindolylmaleimide I inhibits the reaction [Glucose results in increased expression of CCN2 mRNA]; Cadmium inhibits the reaction [Glucose results in increased expression of CCN2 protein]; CCL2 mRNA affects the reaction [Glucose results in increased expression of CCN2 protein]; SB 203580 inhibits the reaction [Glucose results in increased expression of CCN2 protein]; Zinc inhibits the reaction [Glucose results in increased expression of CCN2 protein]
2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [SMARCA4A protein inhibits the reaction [Glucose results in increased expression of CCN2 mRNA]]; SMARCA4A protein inhibits the reaction [Glucose results in increased expression of CCN2 mRNA]
Aspirin inhibits the reaction [Glucose results in increased expression of CCN2 mRNA]; CCN2 protein results in decreased susceptibility to [Oxygen deficiency co-treated with Glucose deficiency]; fatostatin inhibits the reaction [Glucose results in increased expression of CCN2 protein]; HIF1A protein affects the reaction [Glucose results in increased expression of CCN2 protein]; MIR217 mRNA affects the reaction [Glucose results in increased expression of CCN2 protein]; Resveratrol inhibits the reaction [Glucose results in increased expression of CCN2 protein]; SIRT1 protein affects the reaction [Resveratrol inhibits the reaction [Glucose results in increased expression of CCN2 protein]]
Glucose results in increased expression of CCN2 mRNA; Glucose results in increased expression of CCN2 protein
CTD PMID:10026205 PMID:14586741 PMID:19369054 PMID:21124846 PMID:21367880 PMID:22031849 PMID:26891083 PMID:33270355 NCBI chr 1:21,851,657...21,854,773
Ensembl chr 1:21,851,660...21,854,773
JBrowse link
G Ccnd1 cyclin D1 increases expression
multiple interactions
ISO
EXP
Glucose results in increased expression of CCND1; Glucose results in increased expression of CCND1 mRNA
[Oxygen deficiency co-treated with Glucose deficiency] results in increased expression of CCND1 mRNA; cyclopamine inhibits the reaction [[Oxygen deficiency co-treated with Glucose deficiency] results in increased expression of CCND1 mRNA]; cyclopamine inhibits the reaction [polydatin promotes the reaction [[Oxygen deficiency co-treated with Glucose deficiency] results in increased expression of CCND1 mRNA]]; polydatin promotes the reaction [[Oxygen deficiency co-treated with Glucose deficiency] results in increased expression of CCND1 mRNA]
resveratrol inhibits the reaction [Glucose results in increased expression of CCND1 protein]
[Glucose co-treated with resveratrol] results in decreased expression of CCND1 mRNA; resveratrol inhibits the reaction [Glucose results in increased expression of CCND1 mRNA]
CTD PMID:23690508 PMID:24064760 PMID:24971582 PMID:27049278 PMID:27481074 NCBI chr 1:218,090,750...218,100,447
Ensembl chr 1:218,090,750...218,100,325
JBrowse link
G Ccnd2 cyclin D2 multiple interactions ISO [Oxygen deficiency co-treated with Glucose deficiency] results in increased expression of CCND2 mRNA; cyclopamine inhibits the reaction [[Oxygen deficiency co-treated with Glucose deficiency] results in increased expression of CCND2 mRNA]; cyclopamine inhibits the reaction [polydatin promotes the reaction [[Oxygen deficiency co-treated with Glucose deficiency] results in increased expression of CCND2 mRNA]]; polydatin promotes the reaction [[Oxygen deficiency co-treated with Glucose deficiency] results in increased expression of CCND2 mRNA] CTD PMID:27481074 NCBI chr 4:159,674,885...159,697,207
Ensembl chr 4:159,674,885...159,697,207
JBrowse link
G Ccne1 cyclin E1 increases expression
multiple interactions
EXP Glucose results in increased expression of CCNE1 protein
resveratrol inhibits the reaction [Glucose results in increased expression of CCNE1 protein]
CTD PMID:24971582 NCBI chr 1:94,485,830...94,495,112
Ensembl chr 1:94,485,832...94,494,980
JBrowse link
G Ccnl1 cyclin L1 increases expression ISO Glucose results in increased expression of CCNL1 mRNA CTD PMID:17178593 NCBI chr 2:157,747,295...157,759,838
Ensembl chr 2:157,747,542...157,759,838
JBrowse link
G Cd14 CD14 molecule multiple interactions ISO CD14 protein affects the reaction [Glucose promotes the reaction [Lipopolysaccharides results in increased secretion of MMP1 protein]]; Curcumin inhibits the reaction [Glucose promotes the reaction [Lipopolysaccharides results in increased expression of CD14 protein]]; Glucose promotes the reaction [Lipopolysaccharides results in increased expression of CD14 protein] CTD PMID:18180316 NCBI chr18:29,560,341...29,562,290
Ensembl chr18:29,560,365...29,562,153
JBrowse link
G Cd151 CD151 molecule (Raph blood group) multiple interactions EXP CD151 protein results in decreased susceptibility to [Oxygen deficiency co-treated with Glucose deficiency] CTD PMID:21124846 NCBI chr 1:214,446,659...214,450,668
Ensembl chr 1:214,009,784...214,013,765
Ensembl chr 1:214,009,784...214,013,765
JBrowse link
G Cd160 CD160 molecule decreases expression ISO Glucose results in decreased expression of CD160 mRNA CTD PMID:31525975 NCBI chr 2:198,933,681...198,965,380
Ensembl chr 2:198,935,133...198,942,732
JBrowse link
G Cd300a Cd300a molecule increases expression ISO Glucose results in increased expression of CD300A mRNA CTD PMID:31525975 NCBI chr10:103,437,978...103,451,170
Ensembl chr10:103,438,303...103,450,947
JBrowse link
G Cd44 CD44 molecule (Indian blood group) increases expression ISO Glucose results in increased expression of CD44 mRNA CTD PMID:17178593 NCBI chr 3:92,695,083...92,783,820
Ensembl chr 3:92,696,313...92,783,658
JBrowse link
G Cdc42 cell division cycle 42 increases expression
multiple interactions
ISO Glucose results in increased expression of CDC42 mRNA; Glucose results in increased expression of CDC42 protein
Eucalyptol inhibits the reaction [Glucose results in increased expression of CDC42 protein]; Resveratrol inhibits the reaction [Glucose results in increased expression of CDC42 mRNA]; Resveratrol inhibits the reaction [Glucose results in increased expression of CDC42 protein]
CTD PMID:24659233 PMID:31483951 NCBI chr 5:155,690,267...155,728,385
Ensembl chr 5:155,691,390...155,728,300
JBrowse link
G Cdh1 cadherin 1 multiple interactions
decreases expression
ISO [Glucose co-treated with TGFB1 protein] results in decreased expression of CDH1 protein; C646 compound inhibits the reaction [Glucose results in decreased expression of CDH1 protein]; DKK1 protein inhibits the reaction [Glucose results in decreased expression of CDH1 mRNA]; DKK1 protein inhibits the reaction [Glucose results in decreased expression of CDH1 protein]; MAPK14 protein promotes the reaction [[Glucose co-treated with TGFB1 protein] results in decreased expression of CDH1 protein]; MAPK14 protein promotes the reaction [Glucose results in decreased expression of CDH1 protein]
Glucose results in decreased expression of CDH1 mRNA; Glucose results in decreased expression of CDH1 protein
CTD PMID:21829520 PMID:26045780 PMID:29163160 NCBI chr19:38,768,467...38,838,395
Ensembl chr19:38,768,467...38,838,395
JBrowse link
G Cdh5 cadherin 5 decreases expression ISO Glucose results in decreased expression of CDH5 mRNA CTD PMID:31655124 NCBI chr19:1,025,122...1,074,333
Ensembl chr19:1,023,683...1,074,365
JBrowse link
G Cdkn1a cyclin-dependent kinase inhibitor 1A increases expression
multiple interactions
ISO
EXP
Glucose results in increased expression of CDKN1A mRNA
Glucose promotes the reaction [SETD7 protein binds to CDKN1A promoter]; NAD inhibits the reaction [Glucose results in increased expression of CDKN1A protein]; Niacinamide inhibits the reaction [Sirolimus inhibits the reaction [Glucose results in increased expression of CDKN1A protein]]; resveratrol inhibits the reaction [Glucose results in increased expression of CDKN1A protein]; Sirolimus inhibits the reaction [Glucose results in increased expression of CDKN1A protein]; SIRT1 protein promotes the reaction [NAD inhibits the reaction [Glucose results in increased expression of CDKN1A protein]]; SIRT1 protein promotes the reaction [resveratrol inhibits the reaction [Glucose results in increased expression of CDKN1A protein]]; SIRT1 protein promotes the reaction [Sirolimus inhibits the reaction [Glucose results in increased expression of CDKN1A protein]]; TGFB1 protein promotes the reaction [Glucose promotes the reaction [SETD7 protein binds to CDKN1A promoter]]; TGFB1 protein promotes the reaction [Glucose results in increased expression of CDKN1A mRNA]
Glucose results in increased expression of CDKN1A mRNA; Glucose results in increased expression of CDKN1A protein
[Palmitic Acid co-treated with Glucose] results in increased expression of CDKN1A mRNA; resveratrol inhibits the reaction [Glucose results in increased expression of CDKN1A mRNA]; SIRT1 protein mutant form inhibits the reaction [[Palmitic Acid co-treated with Glucose] results in increased expression of CDKN1A mRNA]
CTD PMID:17178593 PMID:22561310 PMID:24451382 PMID:27049278 PMID:27652271 NCBI chr20:6,348,422...6,358,864
Ensembl chr20:6,351,458...6,358,864
JBrowse link
G Cdkn1b cyclin-dependent kinase inhibitor 1B increases expression
multiple interactions
EXP Glucose results in increased expression of CDKN1B protein
NAD inhibits the reaction [Glucose results in increased expression of CDKN1B protein]; Niacinamide inhibits the reaction [Sirolimus inhibits the reaction [Glucose results in increased expression of CDKN1B protein]]; Resveratrol inhibits the reaction [Glucose results in increased expression of CDKN1B protein]; Sirolimus inhibits the reaction [Glucose results in increased expression of CDKN1B protein]; SIRT1 protein promotes the reaction [NAD inhibits the reaction [Glucose results in increased expression of CDKN1B protein]]; SIRT1 protein promotes the reaction [Resveratrol inhibits the reaction [Glucose results in increased expression of CDKN1B protein]]; SIRT1 protein promotes the reaction [Sirolimus inhibits the reaction [Glucose results in increased expression of CDKN1B protein]]
CTD PMID:22561310 NCBI chr 4:168,689,043...168,694,159
Ensembl chr 4:168,689,163...168,693,964
JBrowse link
G Cdkn2a cyclin-dependent kinase inhibitor 2A increases expression
multiple interactions
ISO Glucose results in increased expression of CDKN2A protein alternative form
SIRT3 protein inhibits the reaction [Glucose results in increased expression of CDKN2A protein alternative form]
CTD PMID:23494737 NCBI chr 5:107,823,323...107,832,405
Ensembl chr 5:107,823,330...107,841,175
JBrowse link
G Ceacam1 CEA cell adhesion molecule 1 multiple interactions
decreases expression
decreases secretion
ISO cobaltiprotoporphyrin inhibits the reaction [Glucose results in decreased expression of CEACAM1 mRNA]; cobaltiprotoporphyrin inhibits the reaction [Glucose results in decreased secretion of CEACAM1 protein] CTD PMID:19924377 NCBI chr 1:82,327,955...82,344,345
Ensembl chr 1:82,327,955...82,344,345
JBrowse link
G Cebpa CCAAT/enhancer binding protein alpha multiple interactions ISO CEBPA protein affects the reaction [Glucose results in increased expression of and results in increased secretion of EDN1 protein]; CEBPA protein affects the reaction [Glucose results in increased expression of EDN1 mRNA]; Glucose promotes the reaction [CEBPA protein binds to EDN1 promoter]; Glucose results in increased localization of and results in increased activity of CEBPA protein; pyrazolanthrone inhibits the reaction [Glucose results in increased localization of and results in increased activity of CEBPA protein]; SB 203580 inhibits the reaction [Glucose results in increased localization of and results in increased activity of CEBPA protein]; U 0126 inhibits the reaction [Glucose results in increased localization of and results in increased activity of CEBPA protein] CTD PMID:24376792 NCBI chr 1:91,363,492...91,366,164
Ensembl chr 1:91,363,492...91,366,164
JBrowse link
G Cebpb CCAAT/enhancer binding protein beta multiple interactions ISO CEBPB protein affects the reaction [Glucose results in increased expression of and results in increased secretion of EDN1 protein]; CEBPB protein affects the reaction [Glucose results in increased expression of EDN1 mRNA]; Glucose promotes the reaction [CEBPB protein binds to EDN1 promoter]; Glucose results in increased localization of and results in increased activity of CEBPB protein; pyrazolanthrone inhibits the reaction [Glucose results in increased localization of and results in increased activity of CEBPB protein]; SB 203580 inhibits the reaction [Glucose results in increased localization of and results in increased activity of CEBPB protein]; U 0126 inhibits the reaction [Glucose results in increased localization of and results in increased activity of CEBPB protein]
CEBPB protein inhibits the reaction [Glucose results in decreased expression of PPARGC1A protein]
CTD PMID:24376792 PMID:28482072 NCBI chr 3:164,424,502...164,425,933
Ensembl chr 3:164,424,515...164,425,910
JBrowse link
G Cebpd CCAAT/enhancer binding protein delta multiple interactions ISO CEBPD protein affects the reaction [Glucose results in increased expression of and results in increased secretion of EDN1 protein]; CEBPD protein affects the reaction [Glucose results in increased expression of EDN1 mRNA]; Glucose promotes the reaction [CEBPD protein binds to EDN1 promoter]; Glucose results in increased localization of and results in increased activity of CEBPD protein; pyrazolanthrone inhibits the reaction [Glucose results in increased localization of and results in increased activity of CEBPD protein]; SB 203580 inhibits the reaction [Glucose results in increased localization of and results in increased activity of CEBPD protein]; U 0126 inhibits the reaction [Glucose results in increased localization of and results in increased activity of CEBPD protein] CTD PMID:24376792 NCBI chr11:89,008,008...89,009,146
Ensembl chr11:89,008,008...89,009,146
JBrowse link
G Cert1 ceramide transporter 1 multiple interactions
increases expression
EXP rhodioloside inhibits the reaction [Glucose results in increased expression of CERT1 mRNA]; TXNIP protein affects the reaction [Glucose results in increased expression of CERT1 mRNA] CTD PMID:29031534 NCBI chr 2:27,365,145...27,469,797
Ensembl chr 2:27,365,148...27,469,779
JBrowse link
G Cfap45 cilia and flagella associated protein 45 increases expression ISO Glucose results in increased expression of CFAP45 mRNA CTD PMID:31525975 NCBI chr13:90,909,551...90,932,958
Ensembl chr13:90,909,486...90,932,961
JBrowse link
G Cfd complement factor D decreases expression EXP Glucose results in decreased expression of CFD mRNA CTD PMID:3299706 NCBI chr 7:12,634,216...12,635,939
Ensembl chr 7:12,634,216...12,635,943
JBrowse link
G Cfl1 cofilin 1 increases secretion ISO Glucose deficiency results in increased secretion of CFL1 protein CTD PMID:24802182 NCBI chr 1:220,869,805...220,873,337
Ensembl chr 1:220,869,805...220,873,337
JBrowse link
G Chac1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1 multiple interactions EXP CHAC1 protein results in decreased susceptibility to [Oxygen deficiency co-treated with Glucose deficiency] CTD PMID:21124846 NCBI chr 3:111,160,205...111,163,425
Ensembl chr 3:111,160,205...111,163,425
JBrowse link
G Chd2 chromodomain helicase DNA binding protein 2 multiple interactions ISO Glucose promotes the reaction [TCF19 protein binds to CHD2 protein] CTD PMID:29042441 NCBI chr 1:134,757,934...134,873,053
Ensembl chr 1:134,757,934...134,871,167
JBrowse link
G Chkb choline kinase beta multiple interactions EXP CHKB protein results in decreased susceptibility to [Oxygen deficiency co-treated with Glucose deficiency] CTD PMID:21124846 NCBI chr 7:130,404,818...130,408,813
Ensembl chr 7:130,404,832...130,408,187
JBrowse link
G Chrm2 cholinergic receptor, muscarinic 2 increases expression EXP Glucose results in increased expression of CHRM2 mRNA CTD PMID:18715473 NCBI chr 4:64,089,028...64,091,090
Ensembl chr 4:64,088,900...64,091,090
JBrowse link
G Ckb creatine kinase B multiple interactions
increases activity
ISO Glucose inhibits the reaction [daidzein results in increased activity of CKB protein]; Glucose inhibits the reaction [Dihydrotestosterone results in increased activity of CKB protein]; Glucose inhibits the reaction [Estradiol results in increased activity of CKB protein]; Glucose inhibits the reaction [Genistein results in increased activity of CKB protein]
Glucose results in increased activity of CKB protein
CTD PMID:16621514 NCBI chr 6:136,142,956...136,145,838
Ensembl chr 6:136,142,956...136,145,837
JBrowse link
G Cks2 CDC28 protein kinase regulatory subunit 2 increases expression ISO Glucose results in increased expression of CKS2 mRNA CTD PMID:17178593 NCBI chr17:13,587,664...13,593,423
Ensembl chr17:13,587,665...13,593,423
JBrowse link
G Cnih2 cornichon family AMPA receptor auxiliary protein 2 increases expression ISO Glucose results in increased expression of CNIH2 mRNA CTD PMID:17178593 NCBI chr 1:220,474,485...220,480,723
Ensembl chr 1:220,474,493...220,480,132
JBrowse link
G Cnr1 cannabinoid receptor 1 decreases expression
increases expression
multiple interactions
EXP Glucose results in decreased expression of CNR1 mRNA
Glucose results in increased expression of CNR1 mRNA; Glucose results in increased expression of CNR1 protein
MIR29A mRNA inhibits the reaction [Glucose results in increased expression of CNR1 mRNA]; MIR29A mRNA inhibits the reaction [Glucose results in increased expression of CNR1 protein]
CTD PMID:19501110 PMID:30642005 NCBI chr 5:49,307,584...49,333,064
Ensembl chr 5:49,311,030...49,333,056
JBrowse link
G Col1a1 collagen type I alpha 1 chain affects secretion
increases expression
multiple interactions
ISO
EXP
Glucose deficiency affects the secretion of COL1A1 protein
Glucose results in increased expression of COL1A1 mRNA
DKK1 protein inhibits the reaction [Glucose results in increased expression of COL1A1 mRNA]
Curcumin analog inhibits the reaction [Glucose results in increased expression of COL1A1 mRNA]; Curcumin inhibits the reaction [Glucose results in increased expression of COL1A1 mRNA]
CTD PMID:24802182 PMID:28700904 PMID:29163160 NCBI chr10:82,745,801...82,762,790
Ensembl chr10:82,745,801...82,762,789
JBrowse link
G Col1a2 collagen type I alpha 2 chain multiple interactions
increases secretion
increases expression
ISO troglitazone inhibits the reaction [Glucose results in increased expression of COL1A2 mRNA]
Glucose deficiency results in increased secretion of COL1A2 protein
CTD PMID:17199790 PMID:24802182 NCBI chr 4:31,534,225...31,569,152
Ensembl chr 4:31,534,225...31,569,151
JBrowse link
G Col3a1 collagen type III alpha 1 chain affects secretion ISO Glucose deficiency affects the secretion of COL3A1 protein CTD PMID:24802182 NCBI chr 9:52,023,295...52,059,221
Ensembl chr 9:52,023,295...52,059,217
JBrowse link
G Col4a1 collagen type IV alpha 1 chain multiple interactions
increases expression
EXP
ISO
[eplerenone co-treated with Enalapril] inhibits the reaction [Aldosterone promotes the reaction [Glucose results in increased expression of COL4A1 mRNA]]; Aldosterone promotes the reaction [Glucose results in increased expression of COL4A1 mRNA]; Curcumin analog inhibits the reaction [Glucose results in increased expression of COL4A1 mRNA]; Curcumin inhibits the reaction [Glucose results in increased expression of COL4A1 mRNA]; Enalapril inhibits the reaction [Aldosterone promotes the reaction [Glucose results in increased expression of COL4A1 mRNA]]; eplerenone inhibits the reaction [Aldosterone promotes the reaction [Glucose results in increased expression of COL4A1 mRNA]]
2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [SMARCA4A protein inhibits the reaction [Glucose results in increased expression of COL4A1 mRNA]]; SMARCA4A protein inhibits the reaction [Glucose results in increased expression of COL4A1 mRNA]
CTD PMID:18682491 PMID:28700904 PMID:33270355 NCBI chr16:83,522,162...83,632,153
Ensembl chr16:83,522,162...83,632,153
JBrowse link
G Col4a2 collagen type IV alpha 2 chain affects secretion ISO Glucose deficiency affects the secretion of COL4A2 protein CTD PMID:24802182 NCBI chr16:83,386,388...83,522,169
Ensembl chr16:83,387,364...83,438,561
JBrowse link
G Col5a1 collagen type V alpha 1 chain affects secretion ISO Glucose deficiency affects the secretion of COL5A1 protein CTD PMID:24802182 NCBI chr 3:6,430,180...6,581,010
Ensembl chr 3:6,430,201...6,578,882
JBrowse link
G Col6a1 collagen type VI alpha 1 chain affects secretion ISO Glucose deficiency affects the secretion of COL6A1 protein CTD PMID:24802182 NCBI chr20:12,657,913...12,676,370
Ensembl chr20:12,658,065...12,675,561
JBrowse link
G Col6a2 collagen type VI alpha 2 chain affects secretion ISO Glucose deficiency affects the secretion of COL6A2 protein CTD PMID:24802182 NCBI chr20:12,773,472...12,801,179
Ensembl chr20:12,773,427...12,801,180
JBrowse link
G Commd9 COMM domain containing 9 multiple interactions EXP COMMD9 protein results in decreased susceptibility to [Oxygen deficiency co-treated with Glucose deficiency] CTD PMID:21124846 NCBI chr 3:91,463,612...91,478,097
Ensembl chr 3:91,463,660...91,478,097
JBrowse link
G Cox4i1 cytochrome c oxidase subunit 4i1 increases expression ISO Glucose deficiency results in increased expression of COX4I1 mRNA CTD PMID:26811028 NCBI chr19:54,245,958...54,252,198
Ensembl chr19:54,245,950...54,252,225
JBrowse link
G Cox5b cytochrome c oxidase subunit 5B multiple interactions EXP COX5B protein results in decreased susceptibility to [Oxygen deficiency co-treated with Glucose deficiency] CTD PMID:21124846 NCBI chr 9:43,259,706...43,262,039
Ensembl chr 9:43,259,709...43,262,040
JBrowse link
G Cpt1a carnitine palmitoyltransferase 1A decreases expression ISO Glucose results in decreased expression of CPT1A protein CTD PMID:23090186 NCBI chr 1:218,568,157...218,629,679
Ensembl chr 1:218,569,510...218,629,678
JBrowse link
G Cpt2 carnitine palmitoyltransferase 2 affects expression EXP Glucose affects the expression of CPT2 mRNA CTD PMID:24349266 NCBI chr 5:127,505,646...127,523,016
Ensembl chr 5:127,505,614...127,523,089
JBrowse link
G Creb1 cAMP responsive element binding protein 1 increases activity
multiple interactions
ISO
EXP
Glucose results in increased activity of CREB1 protein
[Oxygen co-treated with Glucose deficiency co-treated with 2-(4-methoxyphenyl)ethyl-2-acetamido-2-deoxyglucopyranoside] results in increased phosphorylation of CREB1 protein; N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [[Oxygen co-treated with Glucose deficiency co-treated with 2-(4-methoxyphenyl)ethyl-2-acetamido-2-deoxyglucopyranoside] results in increased phosphorylation of CREB1 protein]
CTD PMID:15767253 PMID:24726522 NCBI chr 9:71,229,753...71,298,994
Ensembl chr 9:71,230,108...71,293,435
JBrowse link
G Crmp1 collapsin response mediator protein 1 multiple interactions EXP CRMP1 protein results in decreased susceptibility to [Oxygen deficiency co-treated with Glucose deficiency] CTD PMID:21124846 NCBI chr14:78,266,931...78,312,777
Ensembl chr14:78,266,931...78,308,933
JBrowse link
G Csrnp1 cysteine and serine rich nuclear protein 1 increases expression ISO Glucose results in increased expression of CSRNP1 mRNA CTD PMID:17178593 NCBI chr 8:128,659,883...128,673,339
Ensembl chr 8:128,659,868...128,672,284
JBrowse link
G Ctnnb1 catenin beta 1 decreases expression
multiple interactions
increases expression
EXP
ISO
Glucose results in decreased expression of CTNNB1 mRNA; Glucose results in decreased expression of CTNNB1 protein
DKK1 protein inhibits the reaction [Glucose results in increased expression of CTNNB1 mRNA]; DKK1 protein inhibits the reaction [Glucose results in increased expression of CTNNB1 protein]
Glucose results in increased expression of CTNNB1 mRNA; Glucose results in increased expression of CTNNB1 protein
Simvastatin inhibits the reaction [Glucose results in decreased expression of CTNNB1 protein]
CTD PMID:18004065 PMID:21818840 PMID:29163160 NCBI chr 8:129,601,511...129,628,378
Ensembl chr 8:129,617,812...129,627,372
JBrowse link
G Ctsb cathepsin B multiple interactions
increases expression
ISO [Oxygen deficiency co-treated with Glucose deficiency] results in increased expression of CTSB protein; Melatonin inhibits the reaction [[Oxygen deficiency co-treated with Glucose deficiency] results in increased expression of CTSB protein]
Glucose results in increased expression of CTSB mRNA
CTD PMID:17178593 PMID:21392095 NCBI chr15:46,316,741...46,337,613
Ensembl chr15:46,316,741...46,337,612
JBrowse link
G Ctsl cathepsin L increases secretion ISO Glucose deficiency results in increased secretion of CTSL protein CTD PMID:24802182 NCBI chr17:1,873,105...1,879,266
Ensembl chr17:1,872,848...1,879,279
JBrowse link
G Cttn cortactin decreases expression
multiple interactions
ISO Glucose results in decreased expression of CTTN protein
Eucalyptol inhibits the reaction [Glucose results in decreased expression of CTTN protein]
CTD PMID:31483951 NCBI chr 1:217,602,698...217,638,196
NCBI chr 1:215,255,385...215,290,882
Ensembl chr 1:217,602,698...217,638,152
Ensembl chr 1:217,602,698...217,638,152
JBrowse link
G Cx3cl1 C-X3-C motif chemokine ligand 1 multiple interactions
increases expression
ISO 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Glucose results in increased expression of CX3CL1 mRNA]; 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Glucose results in increased expression of CX3CL1 protein]; Clofibrate inhibits the reaction [Glucose results in increased expression of CX3CL1 mRNA]; Clofibrate inhibits the reaction [Glucose results in increased expression of CX3CL1 protein]; Fenofibrate inhibits the reaction [Glucose results in increased expression of CX3CL1 mRNA]; Fenofibrate inhibits the reaction [Glucose results in increased expression of CX3CL1 protein]; SB 203580 inhibits the reaction [Glucose results in increased expression of CX3CL1 mRNA]; SB 203580 inhibits the reaction [Glucose results in increased expression of CX3CL1 protein]
Glucose results in increased expression of CX3CL1 mRNA; Glucose results in increased expression of CX3CL1 protein
CTD PMID:19132243 PMID:31655124 NCBI chr19:10,644,267...10,654,861
Ensembl chr19:10,644,244...10,653,800
JBrowse link
G Cxcl10 C-X-C motif chemokine ligand 10 increases expression ISO Glucose results in increased expression of CXCL10 mRNA CTD PMID:17178593 NCBI chr14:17,210,733...17,212,930
Ensembl chr14:17,210,733...17,212,930
JBrowse link
G Cxcl2 C-X-C motif chemokine ligand 2 increases expression ISO Glucose results in increased expression of CXCL2 mRNA CTD PMID:17178593 NCBI chr14:18,731,346...18,733,391
Ensembl chr14:18,731,378...18,733,391
JBrowse link
G Cxcl3 C-X-C motif chemokine ligand 3 increases expression ISO Glucose results in increased expression of CXCL1 mRNA CTD PMID:17178593 NCBI chr14:18,820,168...18,839,659
Ensembl chr14:18,820,168...18,839,595
JBrowse link
G Cxcr4 C-X-C motif chemokine receptor 4 multiple interactions ISO [Glucose co-treated with Oxygen deficiency] results in decreased expression of CXCR4 mRNA; [Glucose co-treated with Oxygen deficiency] results in decreased expression of CXCR4 protein CTD PMID:18227068 NCBI chr13:45,314,952...45,318,856
Ensembl chr13:45,314,933...45,318,878
JBrowse link
G Cyba cytochrome b-245 alpha chain increases expression
multiple interactions
ISO
EXP
Glucose results in increased expression of CYBA protein
Glucose results in increased expression of CYBA mRNA; Glucose results in increased expression of CYBA protein
[[[Glucose results in increased expression of CYBA protein] co-treated with [Glucose results in increased expression of NCF1 protein]] results in increased chemical synthesis of Reactive Oxygen Species] which results in increased expression of FN1 protein; [[Glucose results in increased expression of CYBA protein] co-treated with [Glucose results in increased expression of NCF1 protein]] results in increased chemical synthesis of Reactive Oxygen Species; CYBA protein promotes the reaction [Glucose results in increased chemical synthesis of Reactive Oxygen Species]; CYBA protein promotes the reaction [Glucose results in increased expression of FN1 protein]; farrerol inhibits the reaction [Glucose results in increased expression of CYBA mRNA]; farrerol inhibits the reaction [Glucose results in increased expression of CYBA protein]; pyrazolanthrone inhibits the reaction [Glucose results in increased expression of CYBA protein]; Resveratrol inhibits the reaction [[[[Glucose results in increased expression of CYBA protein] co-treated with [Glucose results in increased expression of NCF1 protein]] results in increased chemical synthesis of Reactive Oxygen Species] which results in increased expression of FN1 protein]; Resveratrol inhibits the reaction [Glucose results in increased expression of CYBA mRNA]; Resveratrol inhibits the reaction [Glucose results in increased expression of CYBA protein]
dorsomorphin inhibits the reaction [Rosiglitazone inhibits the reaction [Glucose results in increased expression of CYBA protein]]; manganese(III)-tetrakis(4-benzoic acid)porphyrin inhibits the reaction [Glucose results in increased expression of CYBA protein]; Rosiglitazone inhibits the reaction [Glucose results in increased expression of CYBA protein]
CTD PMID:17916771 PMID:18088078 PMID:22245600 PMID:31838053 NCBI chr19:55,249,634...55,257,824
Ensembl chr19:55,249,616...55,257,876
JBrowse link
G Cybb cytochrome b-245 beta chain multiple interactions
increases expression
increases localization
ISO
EXP
acetovanillone inhibits the reaction [Glucose results in increased expression of and results in increased activity of CYBB protein]; FOXP1 protein inhibits the reaction [Glucose results in increased expression of CYBB protein]; Glucose results in increased expression of and results in increased activity of CYBB protein
Glucose results in increased expression of CYBB protein; Glucose results in increased expression of NOX2 mRNA; Glucose results in increased expression of NOX2 protein
dorsomorphin inhibits the reaction [Resveratrol inhibits the reaction [Glucose results in increased expression of CYBB protein]]; Resveratrol inhibits the reaction [Glucose results in increased expression of CYBB protein]
Glucose results in increased localization of CYBB protein
[Oxygen deficiency co-treated with Glucose deficiency] results in increased expression of CYBB protein; Prodigiosin inhibits the reaction [[Oxygen deficiency co-treated with Glucose deficiency] results in increased expression of CYBB protein]; prolinedithiocarbamate inhibits the reaction [[Oxygen deficiency co-treated with Glucose deficiency] results in increased expression of CYBB protein]
CTD PMID:19878672 PMID:21925195 PMID:22253932 PMID:26054749 PMID:31494106 PMID:31838053 NCBI chr  X:14,578,330...14,610,049
Ensembl chr  X:14,578,264...14,612,547
JBrowse link
G Cycs cytochrome c, somatic affects localization
multiple interactions
increases expression
EXP
ISO
Glucose affects the localization of CYCS protein
diallyl trisulfide inhibits the reaction [Glucose results in increased expression of CYCS protein]; MitoTEMPO inhibits the reaction [Glucose results in increased expression of CYCS protein]
naringenin inhibits the reaction [Glucose affects the localization of CYCS protein]
CTD PMID:23192364 PMID:31115753 NCBI chr 4:80,331,226...80,333,326
Ensembl chr 4:80,331,227...80,333,326
JBrowse link
G Cyp11b3 cytochrome P450, family 11, subfamily b, polypeptide 3 decreases expression EXP Glucose results in decreased expression of CYP11B2 mRNA CTD PMID:15017115 NCBI chr 7:116,155,928...116,161,781
Ensembl chr 7:116,156,219...116,255,167
JBrowse link
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 multiple interactions
increases expression
ISO Polyphenols promotes the reaction [Glucose results in increased expression of CYP1A1 mRNA]
CYP1A1 protein affects the reaction [Tetrachlorodibenzodioxin inhibits the reaction [Glucose results in increased secretion of INS1 protein]]
CTD PMID:21682256 PMID:31776611 NCBI chr 8:62,472,087...62,478,122
Ensembl chr 8:62,472,095...62,478,147
JBrowse link
G Cyp1a2 cytochrome P450, family 1, subfamily a, polypeptide 2 multiple interactions ISO CYP1A2 protein affects the reaction [Tetrachlorodibenzodioxin inhibits the reaction [Glucose results in increased secretion of INS1 protein]] CTD PMID:31776611 NCBI chr 8:62,451,360...62,458,244
Ensembl chr 8:62,451,329...62,458,301
JBrowse link
G Cyp1b1 cytochrome P450, family 1, subfamily b, polypeptide 1 multiple interactions ISO [Oxygen co-treated with Glucose] inhibits the reaction [[Oxygen deficiency co-treated with Glucose deficiency] results in decreased expression of CYP1B1 protein]; [Oxygen deficiency co-treated with Glucose deficiency] results in decreased expression of CYP1B1 protein CTD PMID:28400208 NCBI chr 6:2,308,179...2,316,739
Ensembl chr 6:2,307,808...2,316,722
JBrowse link
G Daxx death-domain associated protein multiple interactions
affects localization
ISO Glucose deficiency promotes the reaction [DAXX protein binds to MAP3K5 protein]
Glucose deficiency affects the localization of DAXX protein
CTD PMID:14505347 NCBI chr20:5,480,103...5,485,962
Ensembl chr20:5,480,103...5,485,926
JBrowse link
G Dbi diazepam binding inhibitor, acyl-CoA binding protein increases expression ISO Glucose results in increased expression of DBI mRNA CTD PMID:17178593 NCBI chr13:36,147,667...36,156,076
Ensembl chr13:36,117,119...36,174,908
JBrowse link
G Dbn1 drebrin 1 decreases expression
multiple interactions
EXP Glucose results in decreased expression of DBN1 mRNA; Glucose results in decreased expression of DBN1 protein
Curcumin inhibits the reaction [Glucose results in decreased expression of DBN1 mRNA]
CTD PMID:23333261 NCBI chr17:9,679,511...9,693,878
Ensembl chr17:9,679,628...9,693,820
JBrowse link
G Dcx doublecortin increases expression ISO Glucose results in increased expression of DCX protein CTD PMID:23776576 NCBI chr  X:115,098,675...115,175,515
Ensembl chr  X:115,098,675...115,175,299
JBrowse link
G Ddit3 DNA-damage inducible transcript 3 decreases expression
multiple interactions
increases expression
ISO
EXP
Glucose results in decreased expression of DDIT3 mRNA
[Galactose co-treated with Glucose deficiency] promotes the reaction [leflunomide results in increased expression of DDIT3 protein]
2-aminoethoxydiphenyl borate inhibits the reaction [Glucose results in increased expression of DDIT3 protein]; DDIT3 affects the reaction [Glucose results in decreased expression of PPARGC1A mRNA]; Gadolinium inhibits the reaction [Glucose results in increased expression of DDIT3 protein]; Glucose inhibits the reaction [DDIT3 protein binds to PPARGC1A promoter]; TRPM7 protein affects the reaction [Glucose results in increased expression of DDIT3 protein]; waixenicin A inhibits the reaction [Glucose results in increased expression of DDIT3 protein]
Glucose deficiency results in increased expression of DDIT3 mRNA; Glucose results in increased expression of DDIT3 mRNA; Glucose results in increased expression of DDIT3 protein
Glucose deficiency results in increased expression of DDIT3 protein
CTD PMID:17178593 PMID:21337367 PMID:24349266 PMID:27226639 PMID:28482072 PMID:29427785 PMID:30076216 NCBI chr 7:70,578,564...70,585,074
Ensembl chr 7:70,580,198...70,585,084
JBrowse link
G Ddx3x DEAD-box helicase 3, X-linked increases degradation ISO Glucose deficiency results in increased degradation of DDX3X protein CTD PMID:30821613 NCBI chr  X:10,400,363...10,414,010
Ensembl chr  X:10,400,366...10,413,995
JBrowse link
G Dek DEK proto-oncogene multiple interactions ISO DEK protein affects the chemical synthesis of and affects the uptake of Glucose CTD PMID:28558019 NCBI chr17:17,965,872...17,987,836
Ensembl chr17:17,965,881...17,987,834
JBrowse link
G Dgkd diacylglycerol kinase, delta multiple interactions
affects localization
ISO 2-(1H-indazol-4-yl)-6-(4-methanesulfonylpiperazin-1-ylmethyl)-4-morpholin-4-ylthieno(3,2-d)pyrimidine inhibits the reaction [Glucose affects the localization of DGKD protein alternative form]; 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [Glucose affects the localization of DGKD protein alternative form] CTD PMID:22974639 NCBI chr 9:94,980,328...95,071,531
Ensembl chr 9:94,980,409...95,069,714
JBrowse link
G Dhh desert hedgehog signaling molecule increases expression ISO Glucose results in increased expression of DHH mRNA CTD PMID:31525975 NCBI chr 7:140,575,288...140,580,783
Ensembl chr 7:140,575,288...140,580,783
JBrowse link
G Dhps deoxyhypusine synthase multiple interactions EXP DHPS protein results in decreased susceptibility to [Oxygen deficiency co-treated with Glucose deficiency] CTD PMID:21124846 NCBI chr19:26,184,665...26,188,755
Ensembl chr19:26,184,545...26,188,832
JBrowse link
G Dkk1 dickkopf WNT signaling pathway inhibitor 1 multiple interactions ISO DKK1 protein inhibits the reaction [Glucose results in decreased expression of CDH1 mRNA]; DKK1 protein inhibits the reaction [Glucose results in decreased expression of CDH1 protein]; DKK1 protein inhibits the reaction [Glucose results in increased expression of ACTA2 mRNA]; DKK1 protein inhibits the reaction [Glucose results in increased expression of ACTA2 protein]; DKK1 protein inhibits the reaction [Glucose results in increased expression of COL1A1 mRNA]; DKK1 protein inhibits the reaction [Glucose results in increased expression of CTNNB1 mRNA]; DKK1 protein inhibits the reaction [Glucose results in increased expression of CTNNB1 protein]; DKK1 protein inhibits the reaction [Glucose results in increased expression of FN1 mRNA]; DKK1 protein inhibits the reaction [Glucose results in increased expression of LEF1 mRNA] CTD PMID:29163160 NCBI chr 1:248,952,896...248,956,579
Ensembl chr 1:248,895,738...248,898,607
Ensembl chr 1:248,895,738...248,898,607
JBrowse link
G Dnajb11 DnaJ heat shock protein family (Hsp40) member B11 decreases expression ISO Glucose results in decreased expression of DNAJB11 mRNA CTD PMID:17178593 NCBI chr11:81,741,342...81,757,806
Ensembl chr11:81,741,297...81,757,813
JBrowse link
G Dnajc3 DnaJ heat shock protein family (Hsp40) member C3 decreases expression ISO Glucose results in decreased expression of DNAJC3 mRNA CTD PMID:17178593 NCBI chr15:104,186,918...104,226,236
Ensembl chr15:104,186,792...104,226,329
JBrowse link
G Dnm1l dynamin 1-like increases expression
multiple interactions
EXP
ISO
Glucose results in increased expression of DNM1L protein
diallyl trisulfide inhibits the reaction [Glucose results in increased expression of DNM1L protein]
cinnamic acid inhibits the reaction [Glucose results in increased expression of DNM1L protein]; Metformin inhibits the reaction [Glucose results in increased expression of DNM1L protein]
CTD PMID:27684054 PMID:30144576 PMID:31115753 NCBI chr11:88,830,968...88,882,271
Ensembl chr11:88,830,957...88,880,198
JBrowse link
G Dnmt1 DNA methyltransferase 1 increases expression ISO Glucose results in increased expression of DNMT1 mRNA CTD PMID:29854080 NCBI chr 8:21,922,515...21,968,495
Ensembl chr 8:21,922,515...21,968,495
JBrowse link
G Dpep2 dipeptidase 2 increases expression ISO Glucose results in increased expression of DPEP2 mRNA CTD PMID:31525975 NCBI chr19:37,964,098...37,975,154
Ensembl chr19:37,964,105...37,970,537
JBrowse link
G Dusp1 dual specificity phosphatase 1 increases expression ISO Glucose results in increased expression of DUSP1 mRNA CTD PMID:17178593 NCBI chr10:16,970,642...16,973,425
Ensembl chr10:16,970,626...16,973,418
JBrowse link
G Dusp13 dual specificity phosphatase 13 decreases expression ISO Glucose results in decreased expression of DUSP13 mRNA CTD PMID:31525975 NCBI chr15:2,524,435...2,541,734
Ensembl chr15:2,526,368...2,541,729
Ensembl chr15:2,526,368...2,541,729
Ensembl chr15:2,526,368...2,541,729
Ensembl chr15:2,526,368...2,541,729
JBrowse link
G Dusp2 dual specificity phosphatase 2 increases expression ISO Glucose results in increased expression of DUSP2 mRNA CTD PMID:17178593 NCBI chr 3:119,776,925...119,779,110
Ensembl chr 3:119,776,925...119,779,099
JBrowse link
G Dusp6 dual specificity phosphatase 6 increases expression ISO Glucose results in increased expression of DUSP6 mRNA CTD PMID:17178593 NCBI chr 7:41,475,163...41,479,393
Ensembl chr 7:41,475,163...41,479,392
JBrowse link
G Edem1 ER degradation enhancing alpha-mannosidase like protein 1 decreases expression ISO Glucose results in decreased expression of EDEM1 mRNA CTD PMID:17178593 NCBI chr 4:140,886,644...140,918,654
Ensembl chr 4:140,886,545...140,915,779
JBrowse link
G Edn1 endothelin 1 multiple interactions
decreases expression
increases expression
ISO
EXP
carvedilol inhibits the reaction [Glucose results in increased expression of EDN1 mRNA]; carvedilol inhibits the reaction [Glucose results in increased expression of EDN1 protein]; CAT protein inhibits the reaction [Glucose promotes the reaction [EDN1 protein results in increased chemical synthesis of Inositol 1,4,5-Trisphosphate]]; CEBPA protein affects the reaction [Glucose results in increased expression of and results in increased secretion of EDN1 protein]; CEBPA protein affects the reaction [Glucose results in increased expression of EDN1 mRNA]; CEBPB protein affects the reaction [Glucose results in increased expression of and results in increased secretion of EDN1 protein]; CEBPB protein affects the reaction [Glucose results in increased expression of EDN1 mRNA]; CEBPD protein affects the reaction [Glucose results in increased expression of and results in increased secretion of EDN1 protein]; CEBPD protein affects the reaction [Glucose results in increased expression of EDN1 mRNA]; diphenyleneiodonium inhibits the reaction [Glucose promotes the reaction [EDN1 protein results in increased chemical synthesis of Inositol 1,4,5-Trisphosphate]]; Glucose promotes the reaction [CEBPA protein binds to EDN1 promoter]; Glucose promotes the reaction [CEBPB protein binds to EDN1 promoter]; Glucose promotes the reaction [CEBPD protein binds to EDN1 promoter]; Glucose promotes the reaction [EDN1 protein results in increased chemical synthesis of Inositol 1,4,5-Trisphosphate]; pyrazolanthrone inhibits the reaction [Glucose results in increased expression of EDN1 mRNA]; resveratrol inhibits the reaction [Glucose results in increased expression of EDN1 mRNA]; SB 203580 inhibits the reaction [Glucose results in increased expression of EDN1 mRNA]; U 0126 inhibits the reaction [Glucose results in increased expression of EDN1 mRNA]
Glucose results in decreased expression of EDN1 mRNA
Glucose results in increased expression of EDN1 mRNA; Glucose results in increased expression of EDN1 protein
Glucose affects the reaction [EDN1 protein affects the abundance of and affects the localization of Calcium]; HIF1A protein affects the reaction [Glucose results in increased expression of EDN1 protein]; MIR217 mRNA affects the reaction [Glucose results in increased expression of EDN1 protein]; resveratrol inhibits the reaction [Glucose results in increased expression of EDN1 protein]; SIRT1 protein affects the reaction [resveratrol inhibits the reaction [Glucose results in increased expression of EDN1 protein]]
CTD PMID:12821678 PMID:16428915 PMID:20691780 PMID:20960276 PMID:24376792 PMID:26891083 PMID:31655124 NCBI chr17:22,136,814...22,143,745
Ensembl chr17:22,137,324...22,143,324
JBrowse link
G Edn3 endothelin 3 multiple interactions EXP EDN3 protein inhibits the reaction [SLC5A2 protein results in increased uptake of Glucose] CTD PMID:15127950 NCBI chr 3:172,856,730...172,879,276
Ensembl chr 3:172,856,733...172,880,450
JBrowse link
G Ednra endothelin receptor type A increases expression ISO Glucose results in increased expression of EDNRA mRNA CTD PMID:31655124 NCBI chr19:33,928,356...33,991,703
Ensembl chr19:33,928,356...33,991,703
JBrowse link
G Eef1a1 eukaryotic translation elongation factor 1 alpha 1 multiple interactions EXP EEF1A1 protein results in decreased susceptibility to [Oxygen deficiency co-treated with Glucose deficiency] CTD PMID:21124846 NCBI chr 8:85,838,594...85,841,816
Ensembl chr 8:85,838,869...85,840,818
JBrowse link
G Eef2 eukaryotic translation elongation factor 2 multiple interactions
decreases phosphorylation
ISO resveratrol inhibits the reaction [Glucose results in decreased phosphorylation of EEF2 protein] CTD PMID:19765649 NCBI chr 7:11,401,501...11,406,771
Ensembl chr 7:11,401,501...11,406,771
JBrowse link
G Eef2k eukaryotic elongation factor-2 kinase multiple interactions
increases phosphorylation
ISO resveratrol inhibits the reaction [Glucose results in increased phosphorylation of EEF2K protein] CTD PMID:19765649 NCBI chr 1:190,780,211...190,839,926
Ensembl chr 1:190,780,236...190,842,324
JBrowse link
G Egf epidermal growth factor multiple interactions ISO EGF protein inhibits the reaction [Glucose results in decreased expression of CAV1 mRNA]; EGF protein promotes the reaction [Glucose results in increased expression of TGFA mRNA]; Glucose promotes the reaction [EGF protein results in increased expression of TGFA mRNA] CTD PMID:8638660 PMID:19816600 NCBI chr 2:68,820,616...68,895,537 JBrowse link
G Egr1 early growth response 1 multiple interactions
increases expression
ISO Glucose promotes the reaction [AGT protein results in increased expression of EGR1 mRNA]; Valsartan inhibits the reaction [Glucose promotes the reaction [AGT protein results in increased expression of EGR1 mRNA]]
Glucose results in increased expression of EGR1 mRNA
CTD PMID:17178593 PMID:19225232 NCBI chr18:27,657,903...27,660,101
Ensembl chr18:27,657,628...27,661,429
JBrowse link
G Ehd3 EH-domain containing 3 multiple interactions EXP EHD3 protein results in decreased susceptibility to [Oxygen deficiency co-treated with Glucose deficiency] CTD PMID:21124846 NCBI chr 6:25,076,012...25,102,457
Ensembl chr 6:25,074,955...25,100,977
JBrowse link
G Eif2ak2 eukaryotic translation initiation factor 2-alpha kinase 2 multiple interactions
increases phosphorylation
ISO acetyl-aspartyl-glutamyl-valyl-aspartal inhibits the reaction [Glucose results in increased phosphorylation of EIF2AK2 protein]; Glucose promotes the reaction [EIF2AK2 protein results in increased activity of MAPK14 protein] CTD PMID:18973755 NCBI chr 6:1,428,845...1,466,193
Ensembl chr 6:1,428,834...1,466,201
JBrowse link
G Eif2ak3 eukaryotic translation initiation factor 2 alpha kinase 3 multiple interactions
increases phosphorylation
ISO 4-Quinolones analog inhibits the reaction [Glucose deficiency results in increased phosphorylation of EIF2AK3 protein] CTD PMID:31022492 NCBI chr 4:98,648,513...98,709,695
Ensembl chr 4:98,648,545...98,709,694
JBrowse link
G Eif2s1 eukaryotic translation initiation factor 2 subunit alpha multiple interactions
increases phosphorylation
ISO acetyl-aspartyl-glutamyl-valyl-aspartal inhibits the reaction [Glucose results in increased phosphorylation of EIF2S1 protein]
4-Quinolones analog inhibits the reaction [Glucose deficiency results in increased phosphorylation of EIF2S1 protein]; salubrinal inhibits the reaction [4-Quinolones analog inhibits the reaction [Glucose deficiency results in increased phosphorylation of EIF2S1 protein]]
CTD PMID:18973755 PMID:31022492 NCBI chr 6:102,048,372...102,073,041
Ensembl chr 6:102,048,372...102,073,041
JBrowse link
G Eif4a1 eukaryotic translation initiation factor 4A1 increases degradation ISO Glucose deficiency results in increased degradation of EIF4A1 protein CTD PMID:30821613 NCBI chr10:56,271,257...56,276,764
Ensembl chr10:56,271,257...56,276,764
JBrowse link
G Eif4e eukaryotic translation initiation factor 4E increases phosphorylation
multiple interactions
ISO Glucose results in increased phosphorylation of EIF4E protein
Glucose promotes the reaction [EIF4E protein binds to EIF4G1 protein]; resveratrol inhibits the reaction [Glucose promotes the reaction [EIF4E protein binds to EIF4G1 protein]]; resveratrol inhibits the reaction [Glucose results in increased phosphorylation of EIF4E protein]
CTD PMID:19765649 NCBI chr 2:243,819,616...243,853,987
Ensembl chr 2:243,820,661...243,852,631
JBrowse link
G Eif4ebp1 eukaryotic translation initiation factor 4E binding protein 1 multiple interactions EXP
ISO
resveratrol inhibits the reaction [Glucose results in increased phosphorylation of EIF4EBP1 protein]
[AKT1 protein mutant form results in increased susceptibility to Glucose deficiency] which results in increased phosphorylation of EIF4EBP1 protein
CTD PMID:15806154 PMID:20332614 NCBI chr16:68,954,860...68,968,248
Ensembl chr16:68,954,875...68,968,248
JBrowse link
G Eif4g1 eukaryotic translation initiation factor 4 gamma, 1 multiple interactions ISO Glucose promotes the reaction [EIF4E protein binds to EIF4G1 protein]; resveratrol inhibits the reaction [Glucose promotes the reaction [EIF4E protein binds to EIF4G1 protein]] CTD PMID:19765649 NCBI chr11:83,907,659...83,927,683
Ensembl chr11:83,908,109...83,926,524
JBrowse link
G Eif4h eukaryotic translation initiation factor 4H increases degradation ISO Glucose deficiency results in increased degradation of EIF4H protein CTD PMID:30821613 NCBI chr12:25,093,119...25,109,805
Ensembl chr12:25,093,149...25,109,799
JBrowse link
G Elapor1 endosome-lysosome associated apoptosis and autophagy regulator 1 increases expression ISO Glucose results in increased expression of ELAPOR1 mRNA CTD PMID:31525975 NCBI chr 2:211,243,398...211,323,283
Ensembl chr 2:211,246,068...211,322,719
JBrowse link
G Elk3 ETS transcription factor ELK3 increases expression ISO Glucose results in increased expression of ELK3 mRNA CTD PMID:17178593 NCBI chr 7:34,086,213...34,149,601
Ensembl chr 7:34,086,220...34,121,694
JBrowse link
G Elovl6 ELOVL fatty acid elongase 6 increases expression ISO
EXP
Glucose results in increased expression of ELOVL6 mRNA CTD PMID:15066988 PMID:16790840 NCBI chr 2:234,187,490...234,296,124
Ensembl chr 2:234,189,105...234,296,145
Ensembl chr 2:234,189,105...234,296,145
JBrowse link
G Endog endonuclease G multiple interactions
affects localization
ISO
EXP
[Glucose deficiency co-treated with Acetylcysteine] affects the localization of ENDOG protein; [Glucose deficiency co-treated with CAT] affects the localization of ENDOG protein; [Glucose deficiency co-treated with Tetradecanoylphorbol Acetate] affects the localization of ENDOG protein
Glucose affects the localization of ENDOG protein
CTD PMID:17309078 PMID:23192364 NCBI chr 3:8,741,833...8,744,414
Ensembl chr 3:8,741,766...8,744,592
JBrowse link
G Eno1 enolase 1 decreases secretion ISO Glucose deficiency results in decreased secretion of ENO1 protein CTD PMID:24802182 NCBI chr 5:167,288,223...167,299,610
Ensembl chr 5:167,288,223...167,299,609
JBrowse link
G Eno2 enolase 2 increases secretion ISO Glucose deficiency results in increased secretion of ENO2 protein CTD PMID:24802182 NCBI chr 4:157,285,192...157,294,090
Ensembl chr 4:157,285,179...157,294,047
Ensembl chr 9:157,285,179...157,294,047
JBrowse link
G Entpd1 ectonucleoside triphosphate diphosphohydrolase 1 increases expression ISO Glucose results in increased expression of ENTPD1 mRNA CTD PMID:31525975 NCBI chr 1:259,692,020...259,818,922
Ensembl chr 1:259,739,955...259,819,494
JBrowse link
G Ep300 E1A binding protein p300 multiple interactions
increases expression
ISO [cobaltous chloride co-treated with Glucose] promotes the reaction [HIF1A protein binds to EP300 protein]; ERCC1 protein affects the reaction [Glucose results in increased expression of EP300 mRNA]; ERCC4 protein affects the reaction [Glucose results in increased expression of EP300 mRNA]; scutellarin inhibits the reaction [[cobaltous chloride co-treated with Glucose] promotes the reaction [HIF1A protein binds to EP300 protein]] CTD PMID:22228707 PMID:25192544 PMID:26045780 NCBI chr 7:122,818,194...122,889,055
Ensembl chr 7:122,818,975...122,861,296
JBrowse link
G Ephx4 epoxide hydrolase 4 decreases expression ISO Glucose results in decreased expression of EPHX4 mRNA CTD PMID:31525975 NCBI chr14:3,360,680...3,389,996
Ensembl chr14:3,360,712...3,389,943
JBrowse link
G Epo erythropoietin multiple interactions ISO [EPO protein co-treated with Glucose] results in increased expression of RUNX2 mRNA; [EPO protein co-treated with Glucose] results in increased expression of RUNX2 protein; [EPO protein co-treated with Glucose] results in increased expression of SP7 mRNA; [EPO protein co-treated with Glucose] results in increased expression of SP7 protein CTD PMID:30894315 NCBI chr12:22,274,828...22,278,268
Ensembl chr12:22,274,828...22,278,266
JBrowse link
G Erbb2 erb-b2 receptor tyrosine kinase 2 multiple interactions ISO [Glucose deficiency co-treated with Quercetin] results in increased ubiquitination of ERBB2 protein; Glucose deficiency inhibits the reaction [Quercetin promotes the reaction [ERBB2 protein binds to HSP90AA1 protein]] CTD PMID:18655187 NCBI chr10:86,367,596...86,391,728
Ensembl chr10:86,367,596...86,391,728
JBrowse link
G Erbb3 erb-b2 receptor tyrosine kinase 3 multiple interactions EXP [NRG1 protein binds to ERBB3 protein] which results in increased transport of Glucose CTD PMID:14711829 NCBI chr 7:2,989,202...3,010,610
Ensembl chr 7:2,989,340...3,010,350
JBrowse link
G Ercc1 ERCC excision repair 1, endonuclease non-catalytic subunit multiple interactions
increases expression
ISO 3-aminobenzamide inhibits the reaction [Glucose results in increased expression of ERCC1 mRNA]; 3-aminobenzamide inhibits the reaction [Glucose results in increased expression of ERCC1 protein]; Curcumin inhibits the reaction [Glucose results in increased expression of ERCC1 mRNA]; Curcumin inhibits the reaction [Glucose results in increased expression of ERCC1 protein]; ERCC1 protein affects the reaction [Glucose results in increased expression of EP300 mRNA]; ERCC1 protein affects the reaction [Glucose results in increased expression of ERCC4 mRNA]; ERCC1 protein affects the reaction [Glucose results in increased expression of ERCC4 protein]; ERCC1 protein affects the reaction [Glucose results in increased expression of FN1 mRNA]; ERCC1 protein affects the reaction [Glucose results in increased expression of PARP1 mRNA]; ERCC4 protein affects the reaction [Glucose results in increased expression of ERCC1 mRNA]; ERCC4 protein affects the reaction [Glucose results in increased expression of ERCC1 protein]; trichostatin A inhibits the reaction [Glucose results in increased expression of ERCC1 mRNA]; trichostatin A inhibits the reaction [Glucose results in increased expression of ERCC1 protein]
Glucose results in increased expression of ERCC1 mRNA; Glucose results in increased expression of ERCC1 protein
CTD PMID:22228707 NCBI chr 1:80,256,973...80,268,198
Ensembl chr 1:80,256,973...80,268,198
JBrowse link
G Ercc4 ERCC excision repair 4, endonuclease catalytic subunit increases expression
multiple interactions
ISO Glucose results in increased expression of ERCC4 mRNA; Glucose results in increased expression of ERCC4 protein
3-aminobenzamide inhibits the reaction [Glucose results in increased expression of ERCC4 mRNA]; 3-aminobenzamide inhibits the reaction [Glucose results in increased expression of ERCC4 protein]; Curcumin inhibits the reaction [Glucose results in increased expression of ERCC4 mRNA]; Curcumin inhibits the reaction [Glucose results in increased expression of ERCC4 protein]; ERCC1 protein affects the reaction [Glucose results in increased expression of ERCC4 mRNA]; ERCC1 protein affects the reaction [Glucose results in increased expression of ERCC4 protein]; ERCC4 protein affects the reaction [Glucose results in increased expression of EP300 mRNA]; ERCC4 protein affects the reaction [Glucose results in increased expression of ERCC1 mRNA]; ERCC4 protein affects the reaction [Glucose results in increased expression of ERCC1 protein]; ERCC4 protein affects the reaction [Glucose results in increased expression of FN1 mRNA]; ERCC4 protein affects the reaction [Glucose results in increased expression of PARP1 mRNA]; trichostatin A inhibits the reaction [Glucose results in increased expression of ERCC4 mRNA]; trichostatin A inhibits the reaction [Glucose results in increased expression of ERCC4 protein]
CTD PMID:22228707 NCBI chr10:2,010,140...2,037,953
Ensembl chr10:2,010,648...2,037,891
JBrowse link
G Ern1 endoplasmic reticulum to nucleus signaling 1 increases phosphorylation
multiple interactions
ISO Glucose deficiency results in increased phosphorylation of ERN1 protein
4-Quinolones analog inhibits the reaction [Glucose deficiency results in increased phosphorylation of ERN1 protein]
CTD PMID:31022492 NCBI chr10:94,588,555...94,682,072
Ensembl chr10:94,588,555...94,681,914
JBrowse link
G Ero1a endoplasmic reticulum oxidoreductase 1 alpha decreases expression ISO Glucose results in decreased expression of ERO1A mRNA CTD PMID:17178593 NCBI chr15:19,619,947...19,655,381
Ensembl chr15:19,619,973...19,655,381
JBrowse link
G Esr1 estrogen receptor 1 increases expression
multiple interactions
increases abundance
increases phosphorylation
decreases expression
ISO
EXP
Glucose results in increased expression of ESR1 mRNA
Endosulfan promotes the reaction [ESR1 protein results in increased abundance of Glucose]
Glucose results in increased phosphorylation of ESR1 protein
ESR1 protein promotes the reaction [[resveratrol results in increased localization of SLC2A4 protein] which results in increased uptake of Glucose]
Glucose results in decreased expression of ESR1 mRNA
CTD PMID:16621514 PMID:18426865 PMID:23690508 PMID:31520823 NCBI chr 1:41,192,029...41,594,799
Ensembl chr 1:41,192,824...41,594,796
JBrowse link
G Esr2 estrogen receptor 2 increases expression
decreases expression
ISO Glucose results in increased expression of ESR2 mRNA
Glucose results in decreased expression of ESR2 mRNA
CTD PMID:16621514 NCBI chr 6:99,163,953...99,214,711
Ensembl chr 6:99,164,357...99,214,251
JBrowse link
G Esrra estrogen related receptor, alpha decreases expression
multiple interactions
ISO Glucose results in decreased expression of ESRRA protein
resveratrol inhibits the reaction [Glucose results in decreased expression of ESRRA protein]
CTD PMID:23090186 NCBI chr 1:222,168,729...222,178,842
Ensembl chr 1:222,168,730...222,178,725
JBrowse link
G Ezr ezrin multiple interactions
decreases expression
ISO Eucalyptol inhibits the reaction [Glucose results in decreased expression of EZR protein] CTD PMID:31483951 NCBI chr 1:47,287,872...47,331,412
Ensembl chr 1:47,287,874...47,331,412
JBrowse link
G F2r coagulation factor II (thrombin) receptor decreases expression ISO Glucose results in decreased expression of F2R mRNA CTD PMID:31655124 NCBI chr 2:26,118,760...26,135,340
Ensembl chr 2:26,118,760...26,135,340
JBrowse link
G Fabp4 fatty acid binding protein 4 multiple interactions
increases expression
ISO
EXP
[Glucose deficiency co-treated with ALB protein] results in decreased expression of FABP4 mRNA; [Glucose deficiency co-treated with Clofibrate co-treated with Oleic Acid] results in increased expression of FABP4 mRNA; [Glucose deficiency co-treated with Clofibrate] results in increased expression of FABP4 mRNA; [Glucose deficiency co-treated with Oleic Acid] results in increased expression of FABP4 mRNA
[Glucose co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with INS1 protein] results in increased expression of FABP4 mRNA; avobenzone promotes the reaction [[Glucose co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with INS1 protein] results in increased expression of FABP4 mRNA]; dioxybenzone promotes the reaction [[Glucose co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with INS1 protein] results in increased expression of FABP4 mRNA]; oxybenzone promotes the reaction [[Glucose co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with INS1 protein] results in increased expression of FABP4 mRNA]
Glucose results in increased expression of FABP4 mRNA
CTD PMID:3299706 PMID:8536680 PMID:32407875 NCBI chr 2:93,792,666...93,797,267
Ensembl chr 2:93,792,601...93,797,305
JBrowse link
G Fas Fas cell surface death receptor increases expression
decreases expression
multiple interactions
ISO Glucose results in increased expression of FAS mRNA; Glucose results in increased expression of FAS protein
Glucose results in decreased expression of FAS mRNA
dorsomorphin inhibits the reaction [platycodin D inhibits the reaction [Glucose results in increased expression of FAS mRNA]]; dorsomorphin inhibits the reaction [platycodin D inhibits the reaction [Glucose results in increased expression of FAS protein]]; platycodin D inhibits the reaction [Glucose results in increased expression of FAS mRNA]; platycodin D inhibits the reaction [Glucose results in increased expression of FAS protein]; STO 609 inhibits the reaction [platycodin D inhibits the reaction [Glucose results in increased expression of FAS mRNA]]
CTD PMID:23319015 PMID:31655124 NCBI chr 1:252,589,785...252,624,790
Ensembl chr 1:252,589,785...252,624,790
JBrowse link
G Faslg Fas ligand increases expression ISO Glucose results in increased expression of FASLG mRNA CTD PMID:31655124 NCBI chr13:79,696,811...79,717,581
Ensembl chr13:79,698,445...79,705,705
JBrowse link
G Fasn fatty acid synthase increases expression
multiple interactions
ISO
EXP
Glucose results in increased expression of FASN mRNA
Allopurinol inhibits the reaction [Glucose results in increased expression of FASN protein]; Glucose promotes the reaction [SREBF1 protein binds to FASN promoter]; Quercetin inhibits the reaction [Glucose results in increased expression of FASN protein]
[Glucose results in increased expression of FASN protein] which results in increased abundance of Triglycerides; [INS protein co-treated with Glucose] results in increased expression of FASN mRNA; [Resveratrol results in increased activity of SIRT1 protein] inhibits the reaction [[Glucose results in increased expression of FASN protein] which results in increased abundance of Triglycerides]; Allopurinol inhibits the reaction [Glucose results in increased expression of FASN protein]; PRKAA2 protein promotes the reaction [SIRT1 protein inhibits the reaction [Glucose results in increased expression of FASN protein]]; Quercetin inhibits the reaction [Glucose results in increased expression of FASN protein]; SIRT1 protein inhibits the reaction [Glucose results in increased expression of FASN protein]; SRT1720 inhibits the reaction [[INS protein co-treated with Glucose] results in increased expression of FASN mRNA]
CTD PMID:15066988 PMID:18482975 PMID:19724016 PMID:22031849 PMID:23647015 NCBI chr10:109,987,735...110,005,901
Ensembl chr10:109,987,735...110,005,901
JBrowse link
G Fbxl13 F-box and leucine-rich repeat protein 13 increases expression ISO Glucose results in increased expression of FBXL13 mRNA CTD PMID:31525975 NCBI chr 4:10,020,349...10,170,012
Ensembl chr 4:10,020,349...10,167,023
JBrowse link
G Fbxo32 F-box protein 32 multiple interactions
increases expression
ISO FBXO32 protein affects the reaction [Glucose results in decreased expression of KCNN2 protein]
Glucose results in increased expression of FBXO32 protein
CTD PMID:30635400 NCBI chr 7:98,065,664...98,098,071
Ensembl chr 7:98,063,735...98,098,268
JBrowse link
G Fcer1g Fc fragment of IgE receptor Ig decreases expression ISO Glucose results in decreased expression of FCER1G mRNA CTD PMID:31525975 NCBI chr13:89,601,894...89,606,326
Ensembl chr13:89,601,896...89,606,326
JBrowse link
G Ffar1 free fatty acid receptor 1 decreases expression EXP Glucose results in decreased expression of FFAR1 mRNA CTD PMID:24349266 NCBI chr 1:89,308,475...89,309,379
Ensembl chr 1:89,308,475...89,309,379
JBrowse link
G Fgf1 fibroblast growth factor 1 increases expression ISO Glucose results in increased expression of FGF1 mRNA CTD PMID:31655124 NCBI chr18:32,273,830...32,359,831
Ensembl chr18:32,273,770...32,359,824
JBrowse link
G Fgf2 fibroblast growth factor 2 increases expression
decreases expression
multiple interactions
EXP
ISO
Glucose results in increased expression of FGF2 mRNA; Glucose results in increased expression of FGF2 protein
Glucose results in decreased expression of FGF2 mRNA
Glucosamine promotes the reaction [Glucose results in increased expression of FGF2 mRNA]
CTD PMID:1518840 PMID:19759273 PMID:31655124 NCBI chr 2:124,081,072...124,134,133
Ensembl chr 2:124,081,072...124,134,681
JBrowse link
G Fgf21 fibroblast growth factor 21 affects uptake
increases secretion
multiple interactions
increases expression
ISO FGF21 protein affects the uptake of Glucose
Glucose results in increased secretion of FGF21 protein
indolo(3,2-b)carbazole inhibits the reaction [Glucose deficiency results in increased expression of FGF21 mRNA]; Tetrachlorodibenzodioxin inhibits the reaction [Glucose deficiency results in increased expression of FGF21 mRNA]
indolo(3,2-b)carbazole inhibits the reaction [Glucose results in increased expression of FGF21 mRNA]; Tetrachlorodibenzodioxin inhibits the reaction [Glucose results in increased expression of FGF21 mRNA]
CTD PMID:15902306 PMID:27226639 PMID:28123933 NCBI chr 1:101,595,579...101,596,822
Ensembl chr 1:101,595,579...101,596,822
JBrowse link
G Fgf7 fibroblast growth factor 7 affects transport ISO FGF7 protein affects the transport of Glucose CTD PMID:12757114 NCBI chr 3:118,315,859...118,368,464
Ensembl chr 3:118,317,761...118,366,872
JBrowse link
G Fis1 fission, mitochondrial 1 increases expression
multiple interactions
EXP Glucose results in increased expression of FIS1 protein
cinnamic acid inhibits the reaction [Glucose results in increased expression of FIS1 protein]; Metformin inhibits the reaction [Glucose results in increased expression of FIS1 protein]
CTD PMID:27684054 PMID:30144576 NCBI chr12:22,750,485...22,765,324
Ensembl chr12:22,750,485...22,765,308
JBrowse link
G Flg2 filaggrin family member 2 decreases methylation
decreases expression
ISO Glucose results in decreased methylation of FLG2 promoter
Glucose results in decreased expression of FLG2 mRNA
CTD PMID:31525975 NCBI chr 2:193,480,880...193,485,463
Ensembl chr 2:193,483,793...193,485,313
JBrowse link
G Flt1 Fms related receptor tyrosine kinase 1 decreases expression ISO Glucose results in decreased expression of FLT1 mRNA CTD PMID:31655124 NCBI chr12:9,033,993...9,205,886
Ensembl chr12:9,034,308...9,205,905
JBrowse link
G Fn1 fibronectin 1 increases expression
decreases expression
decreases secretion
multiple interactions
increases secretion
ISO
EXP
Glucose results in increased expression of FN1 mRNA; Glucose results in increased expression of FN1 protein
Glucose results in decreased expression of FN1 mRNA
Glucose deficiency results in decreased secretion of FN1 protein
Glucose results in decreased expression of FN1 protein
2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [[sphingosine 1-phosphate co-treated with Glucose] results in increased expression of FN1 protein]; 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Glucose results in increased expression of FN1 mRNA]; [[[Glucose results in increased expression of CYBA protein] co-treated with [Glucose results in increased expression of NCF1 protein]] results in increased chemical synthesis of Reactive Oxygen Species] which results in increased expression of FN1 protein; [Glucose results in increased chemical synthesis of Reactive Oxygen Species] which results in increased expression of FN1; [JTE 013 binds to and results in decreased activity of S1PR2 protein] inhibits the reaction [[sphingosine 1-phosphate co-treated with Glucose] results in increased expression of FN1 protein]; [sphingosine 1-phosphate co-treated with Glucose] results in increased expression of FN1 protein; acetovanillone inhibits the reaction [Glucose results in increased expression of FN1 protein]; Acetylcysteine inhibits the reaction [Glucose results in increased expression of FN1 protein]; cinnamic aldehyde inhibits the reaction [Glucose results in increased expression of FN1 protein]; CYBA protein promotes the reaction [Glucose results in increased expression of FN1 protein]; diphenyleneiodonium inhibits the reaction [Glucose results in increased expression of FN1 mRNA]; diphenyliodonium inhibits the reaction [Glucose results in increased expression of FN1 mRNA]; farrerol inhibits the reaction [Glucose results in increased expression of FN1 mRNA]; farrerol inhibits the reaction [Glucose results in increased expression of FN1 protein]; HIF1A protein affects the reaction [Glucose results in increased expression of FN1 protein]; LY2109761 inhibits the reaction [Glucose results in increased expression of FN1 mRNA]; manumycin inhibits the reaction [Glucose results in increased expression of FN1 mRNA]; MIR217 mRNA affects the reaction [Glucose results in increased expression of FN1 protein]; N,N-dimethylsphingosine inhibits the reaction [Glucose results in increased expression of FN1 protein]; NCF1 protein promotes the reaction [Glucose results in increased expression of FN1 protein]; Resveratrol inhibits the reaction [[[[Glucose results in increased expression of CYBA protein] co-treated with [Glucose results in increased expression of NCF1 protein]] results in increased chemical synthesis of Reactive Oxygen Species] which results in increased expression of FN1 protein]; Resveratrol inhibits the reaction [Glucose results in increased expression of FN1 protein]; rhodioloside inhibits the reaction [Glucose results in increased expression of FN1 mRNA]; SB 203580 inhibits the reaction [[sphingosine 1-phosphate co-treated with Glucose] results in increased expression of FN1 protein]; SIRT1 protein affects the reaction [Resveratrol inhibits the reaction [Glucose results in increased expression of FN1 protein]]; SPHK1 mRNA affects the reaction [Glucose results in increased expression of FN1 protein]; SPHK1 protein inhibits the reaction [Glucose results in increased expression of FN1 protein]; Superoxides affects the reaction [Glucose results in increased expression of FN1 mRNA]; TXNIP protein affects the reaction [Glucose results in increased expression of FN1 mRNA]; TXNIP protein affects the reaction [Glucose results in increased expression of FN1 protein]; Y 27632 inhibits the reaction [Glucose results in increased expression of FN1 protein]
2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [SMARCA4A protein inhibits the reaction [Glucose results in increased expression of FN1 mRNA]]; 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [SMARCA4A protein inhibits the reaction [Glucose results in increased expression of FN1 protein]]; Enalaprilat inhibits the reaction [Glucose results in increased expression of FN1 mRNA]; NFE2L2 protein affects the reaction [SMARCA4A protein inhibits the reaction [Glucose results in increased expression of FN1 mRNA]]; Resveratrol inhibits the reaction [Glucose results in increased expression of FN1 protein]; SMARCA4A protein inhibits the reaction [Glucose results in increased expression of FN1 mRNA]; SMARCA4A protein inhibits the reaction [Glucose results in increased expression of FN1 protein]; TXNIP promotes the reaction [Glucose results in increased expression of FN1 mRNA]
2-amino-6-chloro-alpha-cyano-3-(ethoxycarbonyl)-4H-1-benzopyran-4-acetic acid ethyl ester inhibits the reaction [FOXP1 protein inhibits the reaction [Glucose results in increased expression of and results in increased secretion of FN1 protein]]; 3-aminobenzamide inhibits the reaction [Glucose results in increased expression of FN1 mRNA]; 6-hydroxy-2,5,7,8-tetramethylchroman-2-carboxylic acid inhibits the reaction [Glucose results in increased expression of FN1 mRNA]; 6-hydroxy-2,5,7,8-tetramethylchroman-2-carboxylic acid inhibits the reaction [Glucose results in increased secretion of FN1 protein]; [Glucose results in increased abundance of Reactive Oxygen Species] which results in increased expression of and results in increased secretion of FN1 protein; acetovanillone inhibits the reaction [Glucose results in increased secretion of FN1 protein]; alpha-Tocopherol inhibits the reaction [Glucose results in increased expression of and results in increased secretion of FN1 protein]; Bosentan inhibits the reaction [Glucose results in increased expression of FN1 mRNA]; Bosentan inhibits the reaction [Glucose results in increased expression of FN1 protein]; BQ 788 inhibits the reaction [Glucose results in increased expression of FN1 mRNA]; C646 compound inhibits the reaction [Glucose results in increased expression of FN1 protein]; calphostin C inhibits the reaction [Glucose results in increased secretion of FN1 protein]; chelerythrine inhibits the reaction [Glucose results in increased expression of FN1 protein]; Curcumin inhibits the reaction [Glucose results in increased expression of FN1 mRNA]; Curcumin inhibits the reaction [Glucose results in increased expression of FN1 protein]; diphenyleneiodonium inhibits the reaction [Glucose results in increased secretion of FN1 protein]; DKK1 protein inhibits the reaction [Glucose results in increased expression of FN1 mRNA]; ERCC1 protein affects the reaction [Glucose results in increased expression of FN1 mRNA]; ERCC4 protein affects the reaction [Glucose results in increased expression of FN1 mRNA]; FOXP1 protein inhibits the reaction [Glucose results in increased expression of and results in increased secretion of FN1 protein]; FOXP1 protein inhibits the reaction [Glucose results in increased expression of FN1 mRNA]; gingerol inhibits the reaction [Glucose results in increased secretion of FN1 protein]; Glucose results in increased expression of and results in increased secretion of FN1 protein; Indomethacin inhibits the reaction [Glucose results in increased secretion of FN1 protein]; MAPK14 protein promotes the reaction [Glucose results in increased secretion of FN1 protein]; pyrrolidine dithiocarbamic acid inhibits the reaction [Glucose results in increased expression of FN1 mRNA]; pyrrolidine dithiocarbamic acid inhibits the reaction [Glucose results in increased expression of FN1 protein]; Rotenone inhibits the reaction [Glucose results in increased secretion of FN1 protein]; sitaxsentan inhibits the reaction [Glucose results in increased expression of FN1 mRNA]; SN50 peptide inhibits the reaction [Glucose results in increased expression of FN1 mRNA]; SN50 peptide inhibits the reaction [Glucose results in increased expression of FN1 protein]; trichostatin A inhibits the reaction [Glucose results in increased expression of FN1 mRNA]; Troglitazone inhibits the reaction [Glucose results in increased expression of FN1 mRNA]
CTD PMID:9225831 PMID:12388107 PMID:14520012 PMID:15086456 PMID:16320596 PMID:16572112 PMID:17178593 PMID:17199790 PMID:19765649 PMID:20060012 PMID:21829520 PMID:21998146 PMID:22228707 PMID:22245600 PMID:22406263 PMID:23376009 PMID:24802182 PMID:26045780 PMID:26891083 PMID:29031534 PMID:29163160 PMID:31494106 PMID:31655124 PMID:31838053 PMID:33270355 NCBI chr 9:78,900,111...78,969,018
Ensembl chr 9:78,900,103...78,969,078
JBrowse link
G Folr1 folate receptor alpha decreases expression ISO Glucose results in decreased expression of FOLR1 mRNA CTD PMID:19616087 NCBI chr 1:166,934,457...166,945,864
Ensembl chr 1:166,934,460...166,943,592
JBrowse link
G Fos Fos proto-oncogene, AP-1 transcription factor subunit increases expression
multiple interactions
ISO
EXP
Glucose results in increased expression of FOS mRNA
Dactinomycin inhibits the reaction [Glucose results in increased expression of FOS mRNA]; Glucose affects the reaction [Adenosine Triphosphate results in increased expression of FOS mRNA]
[Glucose co-treated with Lipopolysaccharides] results in increased expression of FOS protein
CTD PMID:10723097 PMID:11123204 PMID:11557636 PMID:17178593 PMID:18180316 NCBI chr 6:109,300,433...109,303,299
Ensembl chr 6:109,300,433...109,303,299
JBrowse link
G Fosl1 FOS like 1, AP-1 transcription factor subunit increases expression
multiple interactions
ISO Glucose results in increased expression of FOSL1 mRNA
Glucose promotes the reaction [AGT protein results in increased expression of FOSL1 mRNA]
CTD PMID:17178593 PMID:19225232 NCBI chr 1:220,826,560...220,835,066
Ensembl chr 1:220,826,560...220,835,066
JBrowse link
G Fosl2 FOS like 2, AP-1 transcription factor subunit increases expression ISO Glucose results in increased expression of FOSL2 mRNA CTD PMID:17178593 NCBI chr 6:25,598,936...25,616,995
Ensembl chr 6:25,598,936...25,616,995
JBrowse link
G Foxa2 forkhead box A2 multiple interactions ISO [Metformin co-treated with Glucose] affects the localization of FOXA2 protein CTD PMID:16489446 NCBI chr 3:142,383,084...142,387,493
Ensembl chr 3:142,383,278...142,387,481
JBrowse link
G Foxo1 forkhead box O1 increases abundance
decreases response to substance
multiple interactions
EXP
ISO
FOXO1 protein mutant form results in increased abundance of Glucose; FOXO1 protein results in increased abundance of Glucose
FOXO1 protein results in decreased susceptibility to Glucose
Glucose results in increased acetylation of and results in decreased activity of FOXO1 protein; SIRT3 protein inhibits the reaction [Glucose results in increased acetylation of FOXO1 protein]
FOXO1 protein inhibits the reaction [Glucose results in decreased expression of ADIPOR1 mRNA]; FOXO1 protein inhibits the reaction [Glucose results in decreased expression of ADIPOR1 protein]; FOXO1 protein promotes the reaction [resveratrol inhibits the reaction [Glucose results in decreased expression of ADIPOR1 mRNA]]; FOXO1 protein promotes the reaction [resveratrol inhibits the reaction [Glucose results in decreased expression of ADIPOR1 protein]]; Glucose results in increased phosphorylation of and results in decreased activity of FOXO1 protein; INS1 protein inhibits the reaction [FOXO1 protein results in increased abundance of Glucose]; INS1 protein promotes the reaction [FOXO1 protein mutant form results in increased abundance of Glucose]; resveratrol inhibits the reaction [Glucose results in increased phosphorylation of and results in decreased activity of FOXO1 protein]; resveratrol promotes the reaction [FOXO1 protein results in increased abundance of Glucose]
CTD PMID:15788402 PMID:23494737 PMID:24413998 NCBI chr 2:141,451,234...141,527,016
Ensembl chr 2:141,451,234...141,527,016
JBrowse link
G Foxo3 forkhead box O3 multiple interactions
increases phosphorylation
increases localization
ISO
EXP
[[resveratrol results in increased activity of SIRT1 protein] which results in increased phosphorylation of and results in decreased activity of FOXO3 protein] which results in decreased susceptibility to Glucose; AKT1 protein promotes the reaction [Glucose affects the phosphorylation of and affects the activity of FOXO3 protein]; FOXO3 protein promotes the reaction [Glucose results in increased cleavage of and results in increased activity of CASP1 protein]; FOXO3 protein promotes the reaction [Glucose results in increased cleavage of and results in increased activity of CASP3 protein]; Glucose affects the phosphorylation of and affects the activity of FOXO3 protein; resveratrol inhibits the reaction [Glucose results in increased phosphorylation of FOXO3 protein]
2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [Glucose affects the localization of and results in increased phosphorylation of FOXO3 protein]; 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [Resveratrol inhibits the reaction [Glucose results in decreased phosphorylation of and affects the localization of FOXO3 protein]]; 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide inhibits the reaction [Glucose affects the localization of and results in increased phosphorylation of FOXO3 protein]; Acetylcysteine inhibits the reaction [Glucose results in decreased phosphorylation of FOXO3 protein]; Acetylcysteine inhibits the reaction [Glucose results in increased phosphorylation of FOXO3 protein]; Glucose results in decreased phosphorylation of and affects the localization of FOXO3 protein; Glucose results in increased phosphorylation of and affects the localization of FOXO3 protein; Resveratrol inhibits the reaction [Glucose results in decreased phosphorylation of and affects the localization of FOXO3 protein]
Glucose results in increased localization of FOXO3 protein
CTD PMID:20370652 PMID:23090186 PMID:23159718 PMID:25471227 NCBI chr20:46,428,078...46,519,156
Ensembl chr20:46,428,124...46,519,144
JBrowse link
G Foxp1 forkhead box P1 multiple interactions
decreases expression
ISO 2-amino-6-chloro-alpha-cyano-3-(ethoxycarbonyl)-4H-1-benzopyran-4-acetic acid ethyl ester inhibits the reaction [FOXP1 protein inhibits the reaction [Glucose results in increased expression of and results in increased secretion of FN1 protein]]; FOXP1 protein inhibits the reaction [Glucose results in increased expression of and results in increased secretion of FN1 protein]; FOXP1 protein inhibits the reaction [Glucose results in increased expression of CYBB protein]; FOXP1 protein inhibits the reaction [Glucose results in increased expression of FN1 mRNA]; FOXP1 protein inhibits the reaction [Glucose results in increased expression of NOX4 protein]; FOXP1 protein inhibits the reaction [Glucose results in increased phosphorylation of MTOR protein]
Glucose results in decreased expression of FOXP1 mRNA; Glucose results in decreased expression of FOXP1 protein
CTD PMID:31494106 NCBI chr 4:131,362,178...131,963,466
Ensembl chr 4:131,366,744...131,694,755
JBrowse link
G Frk fyn-related Src family tyrosine kinase multiple interactions ISO FRK protein inhibits the reaction [Glucose results in increased secretion of INS1 protein] CTD PMID:17179392 NCBI chr20:41,266,408...41,383,731
Ensembl chr20:41,266,566...41,383,424
JBrowse link
G Fth1 ferritin heavy chain 1 multiple interactions ISO
EXP
FTH1 protein inhibits the reaction [Glucose results in increased abundance of Reactive Oxygen Species]
[[Oxygen deficiency co-treated with Glucose deficiency] results in increased susceptibility to Oxygen] results in increased expression of [FTH1 protein binds to FTL protein]
CTD PMID:16135072 PMID:18931039 NCBI chr 1:226,030,940...226,033,228
Ensembl chr 1:226,030,938...226,033,228
JBrowse link
G Ftl1 ferritin light chain 1 multiple interactions EXP [[Oxygen deficiency co-treated with Glucose deficiency] results in increased susceptibility to Oxygen] results in increased expression of [FTH1 protein binds to FTL protein] CTD PMID:16135072 NCBI chr 1:101,448,190...101,450,034
Ensembl chr 1:101,448,346...101,449,829
JBrowse link
G Fxyd5 FXYD domain-containing ion transport regulator 5 increases expression ISO Glucose results in increased expression of FXYD5 mRNA CTD PMID:17178593 NCBI chr 1:89,464,853...89,474,450
Ensembl chr 1:89,464,860...89,474,252
JBrowse link
G G6pc1 glucose-6-phosphatase catalytic subunit 1 multiple interactions
increases expression
increases activity
decreases expression
ISO
EXP
Glucose promotes the reaction [[ARNT protein binds to G6PC1 promoter] which results in increased expression of G6PC1 mRNA]; Glucose results in increased stability of and results in increased expression of G6PC1 mRNA
Metformin inhibits the reaction [Glucose results in increased expression of G6PC1 mRNA]; tungstate inhibits the reaction [Glucose results in increased activity of G6PC1 protein]; Vanadates inhibits the reaction [Glucose results in increased activity of G6PC1 protein]
Glucose results in decreased expression of G6PC1 mRNA
CTD PMID:14988444 PMID:15767253 PMID:16920846 PMID:19576170 NCBI chr10:89,286,009...89,296,213
Ensembl chr10:89,285,855...89,296,213
JBrowse link
G Gad1 glutamate decarboxylase 1 multiple interactions EXP GAD1 protein results in decreased susceptibility to [Oxygen deficiency co-treated with Glucose deficiency] CTD PMID:25966616 NCBI chr 3:56,861,440...56,902,139
Ensembl chr 3:56,861,396...56,902,157
JBrowse link
G Gadd45g growth arrest and DNA-damage-inducible, gamma increases expression ISO Glucose results in increased expression of GADD45G mRNA CTD PMID:17178593 NCBI chr17:13,391,474...13,393,219
Ensembl chr17:13,391,467...13,393,243
JBrowse link
G Gapdh glyceraldehyde-3-phosphate dehydrogenase multiple interactions
increases ADP-ribosylation
increases expression
ISO
EXP
SOD2 protein inhibits the reaction [[Glucose results in increased chemical synthesis of Superoxides] which results in decreased activity of GAPDH protein]; SOD2 protein inhibits the reaction [Glucose results in decreased activity of and results in increased ADP-ribosylation of GAPDH protein]
PARP1 protein affects the reaction [Glucose results in increased ADP-ribosylation of GAPDH protein]
[chloroacetaldehyde results in decreased activity of GAPDH protein] which results in decreased chemical synthesis of Glucose; UCP1 protein inhibits the reaction [[Glucose results in increased chemical synthesis of Superoxides] which results in decreased activity of GAPDH protein]; UCP1 protein inhibits the reaction [Glucose results in decreased activity of and results in increased ADP-ribosylation of GAPDH protein]
Glucose results in increased expression of GAPDH mRNA
CTD PMID:7826318 PMID:11050244 PMID:14523042 PMID:19733226 NCBI chr 4:157,676,336...157,680,322
Ensembl chr 4:157,676,595...157,679,962
JBrowse link
G Gast gastrin increases secretion EXP Glucose results in increased secretion of GAST protein CTD PMID:19208342 NCBI chr10:88,245,532...88,248,485
Ensembl chr10:88,245,532...88,248,484
JBrowse link
G Gcg glucagon multiple interactions
decreases secretion
increases secretion
increases abundance
ISO
EXP
Glucose inhibits the reaction [[Niacin results in decreased abundance of Fatty Acids, Nonesterified] which results in increased secretion of GCG protein]
Glucose results in decreased secretion of GCG protein
Glucose results in increased secretion of GCG protein
[GCG protein modified form binds to and results in increased activity of GLP1R protein] promotes the reaction [Glucose results in increased secretion of INS1 protein]; Metformin inhibits the reaction [GCG results in increased abundance of Glucose]; troglitazone inhibits the reaction [Glucose results in decreased secretion of GCG protein]; Zinc inhibits the reaction [Glucose results in increased secretion of GCG protein]
[GCG protein modified form binds to and results in increased activity of GLP1R protein] promotes the reaction [Glucose results in increased secretion of INS1 protein]; isosteviol inhibits the reaction [Palmitic Acid promotes the reaction [Glucose results in increased secretion of GCG protein]]; Palmitic Acid promotes the reaction [Glucose results in increased secretion of GCG protein]
CTD PMID:838844 PMID:12914525 PMID:15919803 PMID:18669601 PMID:19002567 PMID:22479612 NCBI chr 3:48,442,635...48,451,650
Ensembl chr 3:48,442,635...48,451,650
JBrowse link
G Gck glucokinase multiple interactions
increases expression
ISO
EXP
[ebselen co-treated with Glucose] results in increased activity of GCK protein; Glucose inhibits the reaction [Alloxan results in decreased expression of GCK mRNA]
Glucose results in increased expression of GCK mRNA
CTD PMID:12137914 PMID:23795780 PMID:24349266 NCBI chr14:86,149,146...86,191,589
Ensembl chr14:86,148,928...86,190,659
JBrowse link
G Gem GTP binding protein overexpressed in skeletal muscle increases expression ISO Glucose results in increased expression of GEM mRNA CTD PMID:17178593 NCBI chr 5:25,339,479...25,353,661
Ensembl chr 5:25,349,928...25,353,661
JBrowse link
G Gh1 growth hormone 1 multiple interactions ISO GH1 protein promotes the reaction [Glucose results in increased phosphorylation of TBC1D4 protein]; Glucose inhibits the reaction [[Niacin results in decreased abundance of Fatty Acids, Nonesterified] which results in increased secretion of GH1 protein] CTD PMID:838844 PMID:21559284 NCBI chr10:94,486,204...94,488,181
Ensembl chr10:94,486,205...94,488,180
JBrowse link
G Ghrl ghrelin and obestatin prepropeptide multiple interactions ISO [homoeriodictyol co-treated with Glucose] results in increased secretion of GHRL protein CTD PMID:28834253 NCBI chr 4:145,674,157...145,678,066
Ensembl chr 4:145,674,157...145,678,066
JBrowse link
G Gja1 gap junction protein, alpha 1 decreases expression
multiple interactions
increases expression
increases degradation
ISO
EXP
Glucose results in decreased expression of GJA1 protein
Chloroquine inhibits the reaction [Resveratrol inhibits the reaction [Glucose results in increased expression of GJA1 protein]]; Chloroquine promotes the reaction [Glucose results in increased expression of GJA1 protein]; Resveratrol inhibits the reaction [Glucose results in increased expression of GJA1 protein]
Glucose results in increased expression of GJA1 mRNA
resveratrol inhibits the reaction [Glucose results in increased degradation of GJA1 protein]
CTD PMID:17178593 PMID:20578705 PMID:28713934 NCBI chr20:37,876,650...37,889,097
Ensembl chr20:37,876,650...37,889,089
JBrowse link
G Gla galactosidase, alpha increases expression ISO Glucose results in increased expression of GLA mRNA CTD PMID:17178593 NCBI chr  X:105,405,915...105,417,331
Ensembl chr  X:105,406,792...105,417,323
JBrowse link
G Glb1 galactosidase, beta 1 increases expression
multiple interactions
ISO
EXP
Glucose results in increased expression of GLB1 protein
NAD inhibits the reaction [Glucose results in increased expression of GLB1 protein]; Niacinamide inhibits the reaction [Sirolimus inhibits the reaction [Glucose results in increased expression of GLB1 protein]]; resveratrol inhibits the reaction [Glucose results in increased expression of GLB1 protein]; Sirolimus inhibits the reaction [Glucose results in increased expression of GLB1 protein]; SIRT1 protein promotes the reaction [NAD inhibits the reaction [Glucose results in increased expression of GLB1 protein]]; SIRT1 protein promotes the reaction [resveratrol inhibits the reaction [Glucose results in increased expression of GLB1 protein]]; SIRT1 protein promotes the reaction [Sirolimus inhibits the reaction [Glucose results in increased expression of GLB1 protein]]
SIRT3 protein inhibits the reaction [Glucose results in increased expression of GLB1 protein]
CTD PMID:17075048 PMID:22561310 PMID:23494737 NCBI chr 8:122,439,328...122,511,939
Ensembl chr 8:122,439,328...122,511,939
JBrowse link
G Gli1 GLI family zinc finger 1 multiple interactions ISO [Oxygen deficiency co-treated with Glucose deficiency] results in increased expression of GLI1 mRNA; [Oxygen deficiency co-treated with Glucose deficiency] results in increased localization of GLI1 protein; cyclopamine inhibits the reaction [[Oxygen deficiency co-treated with Glucose deficiency] results in increased expression of GLI1 mRNA]; cyclopamine inhibits the reaction [[Oxygen deficiency co-treated with Glucose deficiency] results in increased localization of GLI1 protein]; cyclopamine inhibits the reaction [polydatin promotes the reaction [[Oxygen deficiency co-treated with Glucose deficiency] results in increased expression of GLI1 mRNA]]; cyclopamine inhibits the reaction [polydatin promotes the reaction [[Oxygen deficiency co-treated with Glucose deficiency] results in increased localization of GLI1 protein]]; polydatin promotes the reaction [[Oxygen deficiency co-treated with Glucose deficiency] results in increased expression of GLI1 mRNA]; polydatin promotes the reaction [[Oxygen deficiency co-treated with Glucose deficiency] results in increased localization of GLI1 protein] CTD PMID:27481074 NCBI chr 7:70,620,794...70,633,171
Ensembl chr 7:70,620,766...70,630,338
JBrowse link
G Glo1 glyoxalase 1 multiple interactions
decreases expression
ISO GLO1 inhibits the reaction [Glucose promotes the reaction [JUN protein binds to HMGB1 promoter]]; GLO1 inhibits the reaction [Glucose promotes the reaction [JUN protein binds to S100A12 promoter]]; GLO1 inhibits the reaction [Glucose promotes the reaction [JUN protein binds to S100A8 promoter]]; GLO1 inhibits the reaction [Glucose promotes the reaction [RELA protein binds to AGER promoter]]; GLO1 inhibits the reaction [Glucose results in decreased expression of GLO1 protein]; GLO1 inhibits the reaction [Glucose results in increased expression of AGER mRNA]; GLO1 inhibits the reaction [Glucose results in increased expression of AGER protein]; GLO1 inhibits the reaction [Glucose results in increased expression of and results in increased secretion of HMGB1 protein]; GLO1 inhibits the reaction [Glucose results in increased expression of HMGB1 mRNA]; GLO1 inhibits the reaction [Glucose results in increased expression of S100A12 mRNA]; GLO1 inhibits the reaction [Glucose results in increased expression of S100A8 mRNA]; GLO1 inhibits the reaction [Glucose results in increased expression of S100A8 protein]; SOD2 inhibits the reaction [Glucose results in decreased expression of GLO1 protein]; UCP1 inhibits the reaction [Glucose results in decreased expression of GLO1 protein] CTD PMID:19833897 NCBI chr20:9,273,589...9,291,608
Ensembl chr20:9,273,594...9,291,610
JBrowse link
G Glp1r glucagon-like peptide 1 receptor multiple interactions ISO
EXP
[GCG protein modified form binds to and results in increased activity of GLP1R protein] promotes the reaction [Glucose results in increased secretion of INS1 protein]
[GCG protein modified form binds to and results in increased activity of GLP1R protein] promotes the reaction [Glucose results in increased secretion of INS1 protein]; [Glucose co-treated with Oleic Acid] results in decreased expression of GLP1R protein; exenatide inhibits the reaction [[Glucose co-treated with Oleic Acid] results in decreased expression of GLP1R protein]
CTD PMID:18669601 PMID:22925809 NCBI chr20:9,586,075...9,626,228
Ensembl chr20:9,586,075...9,626,228
JBrowse link
G Glrx glutaredoxin multiple interactions ISO GLRX protein inhibits the reaction [[Palmitic Acid co-treated with Glucose] promotes the reaction [Glutathione binds to SIRT1 protein]]; GLRX protein inhibits the reaction [[Palmitic Acid co-treated with Glucose] results in increased oxidation of and results in decreased activity of SIRT1 protein] CTD PMID:24451382 NCBI chr 2:2,606,032...2,615,944
Ensembl chr 2:2,605,996...2,615,944
JBrowse link
G Glud1 glutamate dehydrogenase 1 affects expression EXP Glucose affects the expression of GLUD1 mRNA CTD PMID:24349266 NCBI chr16:10,661,486...10,695,557
Ensembl chr16:10,662,021...10,695,557
JBrowse link
G Glul glutamate-ammonia ligase multiple interactions
decreases expression
EXP Glucose results in decreased expression of and results in decreased activity of GLUL protein; Resveratrol inhibits the reaction [Glucose results in decreased expression of and results in decreased activity of GLUL protein]; Resveratrol inhibits the reaction [Glucose results in decreased expression of GLUL mRNA] CTD PMID:26677078 NCBI chr13:71,331,052...71,340,207
Ensembl chr13:71,331,052...71,340,229
JBrowse link
G Gna11 G protein subunit alpha 11 multiple interactions
increases expression
EXP acetovanillone inhibits the reaction [Glucose results in increased expression of GNA11 protein]; CAT protein inhibits the reaction [Glucose results in increased expression of GNA11 protein] CTD PMID:20691780 NCBI chr 7:11,033,400...11,047,284
Ensembl chr 7:11,033,317...11,047,437
JBrowse link
G Gnai1 G protein subunit alpha i1 decreases expression ISO Glucose results in decreased expression of GNAI1 mRNA CTD PMID:17178593 NCBI chr 4:13,405,136...13,486,866
Ensembl chr 4:13,405,136...13,485,883
JBrowse link
G Gnai2 G protein subunit alpha i2 multiple interactions
decreases expression
ISO
EXP
GNAI2 gene mutant form inhibits the reaction [[Glucose co-treated with Amino Acids] results in increased secretion of INS1 protein]; GNAI2 gene mutant form inhibits the reaction [Glucose results in increased secretion of INS1 protein]
Glucose results in decreased expression of GNAI2 protein
Acetylcysteine inhibits the reaction [Glucose results in decreased expression of GNAI2 protein]; alpha-Tocopherol inhibits the reaction [Glucose results in decreased expression of GNAI2 protein]; diphenyleneiodonium affects the reaction [Glucose results in decreased expression of GNAI2 protein]; manganese(III)-tetrakis(4-benzoic acid)porphyrin inhibits the reaction [Glucose results in decreased expression of GNAI2 protein]; Uric Acid inhibits the reaction [Glucose results in decreased expression of GNAI2 protein]
CTD PMID:18441196 PMID:25205820 NCBI chr 8:116,370,730...116,391,337
Ensembl chr 8:116,370,744...116,391,307
JBrowse link
G Gnai3 G protein subunit alpha i3 multiple interactions
decreases expression
EXP Acetylcysteine inhibits the reaction [Glucose results in decreased expression of GNAI3 protein]; alpha-Tocopherol inhibits the reaction [Glucose results in decreased expression of GNAI3 protein]; diphenyleneiodonium affects the reaction [Glucose results in decreased expression of GNAI3 protein]; manganese(III)-tetrakis(4-benzoic acid)porphyrin inhibits the reaction [Glucose results in decreased expression of GNAI3 protein]; Uric Acid inhibits the reaction [Glucose results in decreased expression of GNAI3 protein] CTD PMID:18441196 NCBI chr 2:210,896,779...210,934,733
Ensembl chr 2:210,896,656...210,934,749
JBrowse link
G Gnaq G protein subunit alpha q multiple interactions
increases expression
EXP acetovanillone inhibits the reaction [Glucose results in increased expression of GNAQ protein]; CAT protein inhibits the reaction [Glucose results in increased expression of GNAQ protein] CTD PMID:20691780 NCBI chr 1:233,382,778...233,622,584
Ensembl chr 1:233,382,708...233,622,786
JBrowse link
G Gng8 G protein subunit gamma 8 decreases expression ISO Glucose results in decreased expression of GNG8 mRNA CTD PMID:31525975 NCBI chr 1:78,818,360...78,822,224
Ensembl chr 1:78,818,404...78,822,224
JBrowse link
G Got1 glutamic-oxaloacetic transaminase 1 increases expression ISO Glucose deficiency results in increased expression of GOT1 mRNA CTD PMID:26811028 NCBI chr 1:263,246,248...263,269,762
Ensembl chr 1:263,246,248...263,269,762
JBrowse link
G Gpd1 glycerol-3-phosphate dehydrogenase 1 increases expression EXP Glucose results in increased expression of GPD1 mRNA CTD PMID:3299706 NCBI chr 7:141,368,928...141,377,931
Ensembl chr 7:141,370,491...141,377,928
JBrowse link
G Gpd2 glycerol-3-phosphate dehydrogenase 2 multiple interactions ISO [GPD2 mutant form co-treated with Aminooxyacetic Acid] inhibits the reaction [Glucose results in increased secretion of INS1 protein]; [Potassium Chloride co-treated with Diazoxide] inhibits the reaction [[GPD2 mutant form co-treated with Aminooxyacetic Acid] inhibits the reaction [Glucose results in increased secretion of INS1 protein]] CTD PMID:10199125 PMID:10464266 NCBI chr 3:43,223,892...43,359,069
Ensembl chr 3:43,255,567...43,359,074
JBrowse link
G Gpt glutamic--pyruvic transaminase multiple interactions EXP Glucose inhibits the reaction [(5'-(4-amino-7,7-dimethyl-2-trifluoromethyl-7H-pyrimido(4,5-b)(1,4)oxazin-6-yl)-2',3'-dihydrospiro(cyclohexane-1,1'-inden)-4-yl)acetic acid results in increased activity of GPT protein] CTD PMID:29479035 NCBI chr 7:117,759,083...117,761,932
Ensembl chr 7:117,759,083...117,761,931
JBrowse link
G Gpx1 glutathione peroxidase 1 decreases expression
multiple interactions
EXP
ISO
Glucose results in decreased expression of GPX1 mRNA
ebselen inhibits the reaction [GPX1 gene mutant form inhibits the reaction [Glucose results in increased secretion of INS1 protein]]; GPX1 gene mutant form inhibits the reaction [Glucose results in increased secretion of INS1 protein]
naringenin inhibits the reaction [Glucose results in decreased expression of GPX1 mRNA]
CTD PMID:21818840 PMID:23192364 PMID:23795780 NCBI chr 8:117,117,430...117,118,528
Ensembl chr 8:117,117,430...117,118,522
JBrowse link
G Gpx2 glutathione peroxidase 2 increases expression EXP Glucose results in increased expression of GPX2 mRNA CTD PMID:28027979 NCBI chr 6:99,839,960...99,843,245
Ensembl chr 6:99,839,960...99,843,245
JBrowse link
G Grem1 gremlin 1, DAN family BMP antagonist increases expression ISO Glucose results in increased expression of GREM1 mRNA CTD PMID:10026205 PMID:10744662 NCBI chr 3:105,203,309...105,214,989
Ensembl chr 3:105,203,309...105,214,989
JBrowse link
G Gria2 glutamate ionotropic receptor AMPA type subunit 2 multiple interactions EXP [Dithionite co-treated with Glucose deficiency] results in decreased expression of GRIA2 protein; Genistein inhibits the reaction [[Dithionite co-treated with Glucose deficiency] results in decreased expression of GRIA2 protein] CTD PMID:27238724 NCBI chr 2:179,584,302...179,704,629
Ensembl chr 2:179,584,308...179,704,629
JBrowse link
G Grin1 glutamate ionotropic receptor NMDA type subunit 1 decreases expression ISO Glucose results in decreased expression of GRIN1 mRNA CTD PMID:31525975 NCBI chr 3:2,507,745...2,534,664
Ensembl chr 3:2,506,896...2,534,663
JBrowse link
G Gsk3b glycogen synthase kinase 3 beta multiple interactions
increases expression
decreases phosphorylation
increases phosphorylation
ISO
EXP
[[ginsenoside Rg2 results in increased phosphorylation of GSK3B protein] co-treated with [ginsenoside Rg2 results in increased expression of NR0B2 mRNA]] results in decreased chemical synthesis of Glucose; Berberine inhibits the reaction [Glucose results in decreased phosphorylation of GSK3B protein]; Glucose inhibits the reaction [INS protein results in increased phosphorylation of GSK3B protein]; N-(oxo-5,6-dihydrophenanthridin-2-yl)-N,N-dimethylacetamide hydrochloride inhibits the reaction [Glucose inhibits the reaction [INS protein results in increased phosphorylation of GSK3B protein]]
Glucose results in increased expression of GSK3B protein
Glucose results in increased phosphorylation of GSK3B protein
[Oxygen deficiency co-treated with Glucose deficiency] results in increased expression of GSK3B mRNA; [Oxygen deficiency co-treated with Glucose deficiency] results in increased expression of GSK3B protein; Glucose results in decreased phosphorylation of and results in increased activity of GSK3B protein; GSK3B protein inhibits the reaction [MIR135A mRNA inhibits the reaction [[Oxygen deficiency co-treated with Glucose deficiency] results in decreased expression of HMOX1 mRNA]]; GSK3B protein inhibits the reaction [MIR135A mRNA inhibits the reaction [[Oxygen deficiency co-treated with Glucose deficiency] results in decreased expression of NFE2L2 protein]]; GSK3B protein inhibits the reaction [MIR135A mRNA inhibits the reaction [[Oxygen deficiency co-treated with Glucose deficiency] results in decreased expression of NQO1 mRNA]]; GSK3B protein inhibits the reaction [MIR135A mRNA inhibits the reaction [[Oxygen deficiency co-treated with Glucose deficiency] results in increased activity of CASP3 protein]]; MIR135A mRNA inhibits the reaction [[Oxygen deficiency co-treated with Glucose deficiency] results in increased expression of GSK3B mRNA]; MIR135A mRNA inhibits the reaction [[Oxygen deficiency co-treated with Glucose deficiency] results in increased expression of GSK3B protein]; Simvastatin inhibits the reaction [Glucose results in decreased phosphorylation of and results in increased activity of GSK3B protein]
[Resveratrol results in increased phosphorylation of GSK3B protein] which results in increased uptake of Glucose; dorsomorphin inhibits the reaction [[Resveratrol results in increased phosphorylation of GSK3B protein] which results in increased uptake of Glucose]; Eucalyptol inhibits the reaction [Glucose results in increased expression of GSK3B protein]; RHOA protein inhibits the reaction [Eucalyptol inhibits the reaction [Glucose results in increased expression of GSK3B protein]]; RHOA protein promotes the reaction [Glucose results in increased expression of GSK3B protein]
CTD PMID:18004065 PMID:21031461 PMID:22062806 PMID:22180358 PMID:23690508 PMID:23954465 PMID:26054749 PMID:29719095 PMID:31483951 NCBI chr11:65,060,884...65,208,842
Ensembl chr11:65,066,235...65,209,268
JBrowse link
G Gsn gelsolin decreases secretion ISO Glucose deficiency results in decreased secretion of GSN protein CTD PMID:24802182 NCBI chr 3:14,456,106...14,508,922
Ensembl chr 3:14,467,330...14,508,911
JBrowse link
G Gsr glutathione-disulfide reductase multiple interactions
decreases activity
decreases expression
ISO
EXP
[Ascorbic Acid co-treated with GSR protein] affects the metabolism of Glucose; [Doxorubicin co-treated with GSR protein] affects the metabolism of Glucose; [Nitrofurantoin co-treated with GSR protein] affects the metabolism of Glucose; Furans analog inhibits the reaction [Glucose results in decreased activity of GSR protein]
naringenin inhibits the reaction [Glucose results in decreased expression of GSR mRNA]
CTD PMID:1901343 PMID:23192364 PMID:28911973 NCBI chr16:62,197,617...62,239,987
Ensembl chr16:62,197,617...62,241,361
JBrowse link
G Gys1 glycogen synthase 1 increases phosphorylation
multiple interactions
EXP Glucose results in increased phosphorylation of GYS1 protein
3,4-Dihydroxyphenylacetic Acid inhibits the reaction [Glucose results in increased phosphorylation of GYS1 protein]; Catechin inhibits the reaction [Glucose results in increased phosphorylation of GYS1 protein]
CTD PMID:29981789 NCBI chr 1:101,427,195...101,447,092
Ensembl chr 1:101,427,195...101,447,092
JBrowse link
G H1f2 H1.2 linker histone, cluster member increases expression ISO Glucose results in increased expression of H1F2 mRNA CTD PMID:17178593 NCBI chr17:43,638,938...43,640,445
Ensembl chr17:43,639,749...43,640,387
JBrowse link
G H3f4 H3.4 histone multiple interactions EXP Glucose promotes the reaction [H3F4 protein modified form binds to PKLR promoter] CTD PMID:16644726 NCBI chr10:45,304,696...45,305,106 JBrowse link
G H4f16 H4 histone 16 multiple interactions EXP Glucose promotes the reaction [H4F16 protein modified form binds to PKLR promoter] CTD PMID:16644726 NCBI chr17:43,821,122...43,821,587 JBrowse link
G Hba-a2 hemoglobin alpha, adult chain 2 increases glycation ISO Glucose results in increased glycation of HBA1 protein CTD PMID:26163454 NCBI chr10:15,589,364...15,590,207
Ensembl chr10:15,589,364...15,590,220
JBrowse link
G Hbb hemoglobin subunit beta multiple interactions
affects binding
ISO
EXP
Furans analog inhibits the reaction [Glucose binds to HBB protein]
Fructose promotes the reaction [Glucose binds to HBB protein]; geraniol inhibits the reaction [Fructose promotes the reaction [Glucose binds to HBB protein]]; Pioglitazone inhibits the reaction [Fructose promotes the reaction [Glucose binds to HBB protein]]
CTD PMID:25679220 PMID:28911973 NCBI chr 1:168,971,269...168,972,680
Ensembl chr 1:168,971,274...168,972,725
JBrowse link
G Hbegf heparin-binding EGF-like growth factor increases expression ISO Glucose results in increased expression of HBEGF mRNA CTD PMID:17178593 NCBI chr18:29,330,302...29,340,185
Ensembl chr18:29,329,764...29,340,403
JBrowse link
G Hdac1 histone deacetylase 1 multiple interactions ISO Glucose promotes the reaction [HDAC1 protein binds to TUG1 promoter] CTD PMID:32467232 NCBI chr 5:147,716,664...147,743,723
Ensembl chr 5:147,716,664...147,743,723
JBrowse link
G Herpud1 homocysteine inducible ER protein with ubiquitin like domain 1 decreases expression ISO Glucose results in decreased expression of HERPUD1 mRNA CTD PMID:17178593 NCBI chr19:11,046,905...11,057,440
Ensembl chr19:11,046,909...11,057,254
JBrowse link
G Hibch 3-hydroxyisobutyryl-CoA hydrolase decreases secretion ISO Glucose deficiency results in decreased secretion of HIBCH protein CTD PMID:24802182 NCBI chr 9:53,446,185...53,526,727
Ensembl chr 9:53,446,194...53,526,728
JBrowse link
G Hif1a hypoxia inducible factor 1 subunit alpha multiple interactions
decreases expression
increases expression
ISO
EXP
2-Methoxyestradiol inhibits the reaction [Glucose results in increased expression of HIF1A protein]; 3-(5'-hydroxymethyl-2'-furyl)-1-benzylindazole inhibits the reaction [Glucose results in increased expression of HIF1A protein]; [3-(5'-hydroxymethyl-2'-furyl)-1-benzylindazole results in decreased activity of HIF1A protein] results in decreased susceptibility to [Oxygen deficiency co-treated with Glucose deficiency]; [Glucose co-treated with Oxygen deficiency] inhibits the reaction [ARNT protein binds to HIF1A protein]; [Glucose co-treated with Oxygen deficiency] promotes the reaction [Pyruvaldehyde binds to and results in decreased activity of HIF1A protein]; [Glucose co-treated with SOD2 gene mutant form] results in decreased expression of HIF1A protein; [Oxygen deficiency co-treated with Glucose deficiency] results in increased expression of HIF1A mRNA; [Oxygen deficiency co-treated with Glucose deficiency] results in increased expression of HIF1A protein
Glucose results in decreased expression of HIF1A mRNA
Glucose results in increased expression of HIF1A mRNA; Glucose results in increased expression of HIF1A protein
[cobaltous chloride co-treated with Glucose] promotes the reaction [HIF1A protein binds to EP300 protein]; [cobaltous chloride co-treated with Glucose] results in increased expression of and results in decreased ubiquitination of HIF1A protein; [Oxygen co-treated with Glucose] inhibits the reaction [[Oxygen deficiency co-treated with Glucose deficiency] results in increased expression of HIF1A protein]; [Oxygen deficiency co-treated with Glucose deficiency] results in increased expression of HIF1A protein; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [scutellarin inhibits the reaction [[cobaltous chloride co-treated with Glucose] results in increased expression of HIF1A protein]]; Cycloheximide inhibits the reaction [[cobaltous chloride co-treated with Glucose] results in increased expression of HIF1A protein]; epoxomicin inhibits the reaction [scutellarin inhibits the reaction [[cobaltous chloride co-treated with Glucose] results in increased expression of HIF1A protein]]; Glucose affects the reaction [Fusaric Acid affects the expression of HIF1A protein]; MG 262 inhibits the reaction [scutellarin inhibits the reaction [[cobaltous chloride co-treated with Glucose] results in increased expression of HIF1A protein]]; Particulate Matter inhibits the reaction [[Oxygen deficiency co-treated with Glucose deficiency] results in increased expression of HIF1A protein]; scutellarin inhibits the reaction [[cobaltous chloride co-treated with Glucose co-treated with Cycloheximide] results in decreased expression of HIF1A protein]; scutellarin inhibits the reaction [[cobaltous chloride co-treated with Glucose] promotes the reaction [HIF1A protein binds to EP300 protein]]; scutellarin inhibits the reaction [[cobaltous chloride co-treated with Glucose] results in increased expression of and results in decreased ubiquitination of HIF1A protein]; scutellarin promotes the reaction [Cycloheximide inhibits the reaction [[cobaltous chloride co-treated with Glucose] results in increased expression of HIF1A protein]]; Vehicle Emissions inhibits the reaction [[Oxygen deficiency co-treated with Glucose deficiency] results in increased expression of HIF1A protein]
[[Glucose deficiency co-treated with Oxygen deficiency] results in increased expression of HIF1A protein] which results in increased expression of SLC8A1 mRNA; [Glucose deficiency co-treated with Oxygen deficiency] results in increased expression of HIF1A protein; [Oxygen deficiency co-treated with Glucose deficiency co-treated with Oxygen] results in increased expression of HIF1A mRNA; [Oxygen deficiency co-treated with Glucose deficiency co-treated with Oxygen] results in increased expression of HIF1A protein; HIF1A protein affects the reaction [Glucose results in increased expression of CCN2 protein]; HIF1A protein affects the reaction [Glucose results in increased expression of EDN1 protein]; HIF1A protein affects the reaction [Glucose results in increased expression of FN1 protein]; HIF1A protein affects the reaction [Glucose results in increased expression of TGFB1 protein]; HIF1A protein affects the reaction [Glucose results in increased expression of VEGFA protein]; MIR217 mRNA affects the reaction [Glucose results in increased expression of HIF1A mRNA]; MIR217 mRNA affects the reaction [Glucose results in increased expression of HIF1A protein]; Resveratrol inhibits the reaction [[Oxygen deficiency co-treated with Glucose deficiency co-treated with Oxygen] results in increased expression of HIF1A mRNA]; Resveratrol inhibits the reaction [[Oxygen deficiency co-treated with Glucose deficiency co-treated with Oxygen] results in increased expression of HIF1A protein]; Resveratrol inhibits the reaction [Glucose results in increased expression of HIF1A mRNA]; Resveratrol inhibits the reaction [Glucose results in increased expression of HIF1A protein]; SIRT1 protein affects the reaction [Resveratrol inhibits the reaction [Glucose results in increased expression of HIF1A protein]]
CTD PMID:18227068 PMID:19228841 PMID:19429140 PMID:21293012 PMID:21617913 PMID:23108914 PMID:23421680 PMID:25192544 PMID:26891083 PMID:28400208 PMID:31654802 PMID:31655124 NCBI chr 6:96,810,868...96,856,303
Ensembl chr 6:96,810,907...96,856,052
JBrowse link
G Hist1h2bc histone cluster 1, H2bc increases expression ISO Glucose results in increased expression of H2BC4 mRNA CTD PMID:17178593 NCBI chr17:44,736,184...44,738,393
Ensembl chr17:44,737,950...44,738,330
Ensembl chr17:44,737,950...44,738,330
JBrowse link
G Hk1 hexokinase 1 increases expression ISO Glucose results in increased expression of HK1 mRNA CTD PMID:17178593 NCBI chr20:31,911,460...31,979,780
Ensembl chr20:31,912,262...31,956,649
JBrowse link
G Hmga2 high mobility group AT-hook 2 increases expression ISO Glucose results in increased expression of HMGA2 mRNA CTD PMID:17178593 NCBI chr 7:65,159,944...65,275,408
Ensembl chr 7:65,159,944...65,275,408
JBrowse link
G Hmgb1 high mobility group box 1 multiple interactions
increases secretion
increases expression
ISO GLO1 inhibits the reaction [Glucose promotes the reaction [JUN protein binds to HMGB1 promoter]]; GLO1 inhibits the reaction [Glucose results in increased expression of and results in increased secretion of HMGB1 protein]; GLO1 inhibits the reaction [Glucose results in increased expression of HMGB1 mRNA]; Glucose promotes the reaction [JUN protein binds to HMGB1 promoter]; Glucose results in increased expression of and results in increased secretion of HMGB1 protein; JUN promotes the reaction [Glucose results in increased expression of HMGB1 mRNA]; SOD2 inhibits the reaction [Glucose results in increased expression of and results in increased secretion of HMGB1 protein]; SOD2 inhibits the reaction [Glucose results in increased expression of HMGB1 mRNA]; UCP1 inhibits the reaction [Glucose results in increased expression of and results in increased secretion of HMGB1 protein]; UCP1 inhibits the reaction [Glucose results in increased expression of HMGB1 mRNA]
Glucose results in increased secretion of HMGB1 protein
NLRP3 protein promotes the reaction [Glucose results in increased secretion of HMGB1 protein]
CTD PMID:19833897 PMID:27783111 NCBI chr12:7,082,529...7,090,246
Ensembl chr16:37,500,017...37,502,237
JBrowse link
G Hmox1 heme oxygenase 1 multiple interactions
decreases expression
affects expression
increases expression
decreases activity
ISO
EXP
2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [spiraeoside inhibits the reaction [Glucose results in decreased expression of HMOX1 protein]]; 2-chloro-5-nitrobenzanilide inhibits the reaction [Rosiglitazone inhibits the reaction [Glucose results in decreased expression of HMOX1 protein]]; [Oxygen co-treated with Glucose] promotes the reaction [Vehicle Emissions promotes the reaction [[Oxygen deficiency co-treated with Glucose deficiency] results in increased expression of HMOX1 protein]]; [Oxygen deficiency co-treated with Glucose deficiency] results in increased expression of HMOX1 protein; Berberine promotes the reaction [Glucose results in increased expression of HMOX1 protein]; Glucose promotes the reaction [cobaltiprotoporphyrin results in increased expression of HMOX1 mRNA]; Glucose promotes the reaction [tin mesoporphyrin results in increased expression of HMOX1 mRNA]; Particulate Matter promotes the reaction [[Oxygen deficiency co-treated with Glucose deficiency] results in increased expression of HMOX1 protein]; Rosiglitazone inhibits the reaction [Glucose results in decreased expression of HMOX1 protein]; spiraeoside inhibits the reaction [Glucose results in decreased expression of HMOX1 protein]; Vehicle Emissions promotes the reaction [[Oxygen deficiency co-treated with Glucose deficiency] results in increased expression of HMOX1 protein]
2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [[diallyl trisulfide co-treated with Glucose] results in increased expression of HMOX1 protein]; [cobaltiprotoporphyrin results in increased expression of HMOX1 protein] which results in decreased susceptibility to Glucose; [diallyl trisulfide co-treated with Glucose] results in increased expression of HMOX1 protein; [Oxygen deficiency co-treated with Glucose deficiency] results in decreased expression of HMOX1 mRNA; Acetylcysteine affects the reaction [Glucose affects the expression of HMOX1 mRNA]; Antioxidants inhibits the reaction [Glucose results in increased expression of HMOX1]; cobaltiprotoporphyrin inhibits the reaction [Glucose results in decreased activity of HMOX1 protein]; cobaltiprotoporphyrin promotes the reaction [Glucose results in increased expression of HMOX1 protein]; Glucose results in decreased activity of and results in increased expression of HMOX1 protein; GSK3B protein inhibits the reaction [MIR135A mRNA inhibits the reaction [[Oxygen deficiency co-treated with Glucose deficiency] results in decreased expression of HMOX1 mRNA]]; HMOX1 protein affects the reaction [Propofol inhibits the reaction [Glucose results in decreased phosphorylation of STAT3 protein]]; HMOX1 protein affects the reaction [Propofol inhibits the reaction [Glucose results in increased cleavage of CASP3 protein]]; HMOX1 protein affects the reaction [Propofol inhibits the reaction [Glucose results in increased expression of ACTA1 mRNA]]; HMOX1 protein affects the reaction [Propofol inhibits the reaction [Glucose results in increased expression of NPPA mRNA]]; HMOX1 protein promotes the reaction [diallyl trisulfide inhibits the reaction [[Oxygen deficiency co-treated with Glucose deficiency] results in increased expression of CASP3 protein modified form]]; manganese(III)-tetrakis(4-benzoic acid)porphyrin affects the reaction [Glucose affects the expression of HMOX1 mRNA]; MIR135A mRNA inhibits the reaction [[Oxygen deficiency co-treated with Glucose deficiency] results in decreased expression of HMOX1 mRNA]; Propofol inhibits the reaction [Glucose results in decreased activity of HMOX1 protein]; Propofol promotes the reaction [Glucose results in increased expression of HMOX1 protein]; Quercetin inhibits the reaction [Glucose results in decreased expression of HMOX1 mRNA]; Quercetin inhibits the reaction [Glucose results in decreased expression of HMOX1 protein]; zinc protoporphyrin inhibits the reaction [cobaltiprotoporphyrin inhibits the reaction [Glucose results in decreased activity of HMOX1 protein]]; zinc protoporphyrin inhibits the reaction [cobaltiprotoporphyrin promotes the reaction [Glucose results in increased expression of HMOX1 protein]]; zinc protoporphyrin inhibits the reaction [Propofol inhibits the reaction [Glucose results in decreased activity of HMOX1 protein]]; zinc protoporphyrin inhibits the reaction [Propofol promotes the reaction [Glucose results in increased expression of HMOX1 protein]]
Glucose results in decreased expression of HMOX1 mRNA; Glucose results in decreased expression of HMOX1 protein
Glucose results in increased expression of HMOX1 mRNA; Glucose results in increased expression of HMOX1 protein
2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [SMARCA4A protein promotes the reaction [Glucose results in increased expression of HMOX1 protein]]; [Oxygen deficiency co-treated with Glucose deficiency] results in increased expression of HMOX1 mRNA; Antioxidants inhibits the reaction [Glucose results in increased expression of HMOX1 mRNA]; Glucose deficiency promotes the reaction [Simvastatin results in increased expression of HMOX1 mRNA]; Glucose deficiency promotes the reaction [Simvastatin results in increased expression of HMOX1 protein]; MIR144 mRNA inhibits the reaction [[Oxygen deficiency co-treated with Glucose deficiency] results in increased expression of HMOX1 mRNA]; NFE2L2 mutant form inhibits the reaction [Glucose deficiency promotes the reaction [Simvastatin results in increased expression of HMOX1 mRNA]]; SMARCA4A protein promotes the reaction [Glucose results in increased expression of HMOX1 protein]; zinc protoporphyrin inhibits the reaction [Glucose deficiency promotes the reaction [Simvastatin results in increased expression of HMOX1 protein]]
Glucose deficiency results in increased expression of HMOX1 mRNA; Glucose results in increased expression of HMOX1 protein
Glucose results in decreased activity of HMOX1 promoter
CTD PMID:14766238 PMID:16464909 PMID:17928392 PMID:19489000 PMID:19924377 PMID:21333731 PMID:22111038 PMID:22643931 PMID:23453443 PMID:23770986 PMID:23954465 PMID:24810525 PMID:25896937 PMID:28400208 PMID:29457851 PMID:29649567 PMID:29719095 PMID:32602595 PMID:33270355 NCBI chr19:14,508,634...14,515,455
Ensembl chr19:14,508,616...14,515,456
JBrowse link
G Hnf1a HNF1 homeobox A affects response to substance ISO HNF1A gene mutant form affects the susceptibility to Glucose CTD PMID:15787664 NCBI chr12:47,407,811...47,433,342
Ensembl chr12:47,407,811...47,433,342
JBrowse link
G Hnf4a hepatocyte nuclear factor 4, alpha multiple interactions
increases expression
decreases expression
ISO Cerulenin inhibits the reaction [Glucose results in decreased expression of HNF4A mRNA]; Glucose affects the reaction [HNF4A protein binds to SHBG promoter]
Glucose results in increased expression of HNF4A mRNA
CTD PMID:17992261 PMID:31525975 NCBI chr 3:159,902,441...159,965,003
Ensembl chr 3:159,902,441...159,965,003
JBrowse link
G Hnrnpk heterogeneous nuclear ribonucleoprotein K decreases expression EXP Glucose results in decreased expression of HNRNPK mRNA; Glucose results in decreased expression of HNRNPK protein CTD PMID:16837467 NCBI chr17:6,664,730...6,676,753
Ensembl chr17:6,665,659...6,676,654
JBrowse link
G Hoxa2 homeobox A2 increases expression EXP Glucose results in increased expression of HOXA2 mRNA CTD PMID:21818840 NCBI chr 4:82,130,441...82,134,846
Ensembl chr 4:82,131,329...82,133,605
JBrowse link
G Hp haptoglobin affects secretion ISO Glucose deficiency affects the secretion of HP protein CTD PMID:24802182 NCBI chr19:42,096,255...42,100,805
Ensembl chr19:42,097,995...42,100,804
JBrowse link
G Hpgds hematopoietic prostaglandin D synthase increases expression ISO Glucose results in increased expression of HPGDS mRNA CTD PMID:31525975 NCBI chr 4:95,945,356...95,970,666
Ensembl chr 4:95,946,025...95,970,666
JBrowse link
G Hprt1 hypoxanthine phosphoribosyltransferase 1 decreases expression ISO Glucose results in decreased expression of HPRT1 mRNA CTD PMID:31655124 NCBI chr  X:158,196,640...158,228,815
Ensembl chr  X:158,197,149...158,228,749
Ensembl chr  X:158,197,149...158,228,749
JBrowse link
G Hras HRas proto-oncogene, GTPase multiple interactions
increases activity
EXP manumycin inhibits the reaction [Glucose results in increased activity of HRAS protein] CTD PMID:16572112 NCBI chr 1:214,178,404...214,181,841
Ensembl chr 1:214,178,407...214,181,686
JBrowse link
G Hsd11b2 hydroxysteroid 11-beta dehydrogenase 2 decreases expression EXP Glucose results in decreased expression of HSD11B2 mRNA CTD PMID:15017115 NCBI chr19:37,476,083...37,481,326
Ensembl chr19:37,476,095...37,481,307
JBrowse link
G Hsd3b1 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1 increases expression ISO Glucose results in increased expression of HSD3B1 mRNA CTD PMID:31525975
G Hsp90aa1 heat shock protein 90 alpha family class A member 1 multiple interactions ISO Glucose deficiency inhibits the reaction [Quercetin promotes the reaction [ERBB2 protein binds to HSP90AA1 protein]] CTD PMID:18655187 NCBI chr 6:135,107,262...135,112,793
Ensembl chr 6:135,107,271...135,112,775
Ensembl chr 6:135,107,271...135,112,775
JBrowse link
G Hsp90b1 heat shock protein 90 beta family member 1 decreases expression
increases secretion
ISO Glucose results in decreased expression of HSP90B1 mRNA
Glucose deficiency results in increased secretion of HSP90B1 protein
CTD PMID:17178593 PMID:24802182 NCBI chr 7:27,226,570...27,240,533
Ensembl chr 7:27,226,569...27,240,533
JBrowse link
G Hspa12a heat shock protein family A (Hsp70) member 12A decreases expression
multiple interactions
EXP Glucose results in decreased expression of HSPA12A protein
KU-32 compound inhibits the reaction [Glucose results in decreased expression of HSPA12A protein]
CTD PMID:22413817 NCBI chr 1:279,946,809...280,104,366
Ensembl chr 1:279,946,811...280,015,358
JBrowse link
G Hspa13 heat shock protein family A (Hsp70) member 13 decreases expression ISO Glucose results in decreased expression of HSPA13 mRNA CTD PMID:17178593 NCBI chr11:14,146,515...14,160,697
Ensembl chr11:14,144,130...14,160,892
JBrowse link
G Hspa5 heat shock protein family A (Hsp70) member 5 increases expression
multiple interactions
decreases expression
ISO
EXP
Glucose deficiency results in increased expression of HSPA5 mRNA; Glucose deficiency results in increased expression of HSPA5 protein; Glucose results in increased expression of HSPA5 mRNA; Glucose results in increased expression of HSPA5 protein
2-aminoethoxydiphenyl borate inhibits the reaction [Glucose results in increased expression of HSPA5 protein]; Gadolinium inhibits the reaction [Glucose results in increased expression of HSPA5 protein]; Glucose affects the reaction [bisphenol A results in decreased expression of HSPA5 protein]; waixenicin A inhibits the reaction [Glucose results in increased expression of HSPA5 protein]
4-Quinolones analog inhibits the reaction [Glucose deficiency results in increased expression of HSPA5 mRNA]; 4-Quinolones analog inhibits the reaction [Glucose deficiency results in increased expression of HSPA5 protein]; ATF6 protein modified form promotes the reaction [4-Quinolones analog inhibits the reaction [Glucose deficiency results in increased expression of HSPA5 protein]]; glucogallin inhibits the reaction [Glucose results in increased expression of HSPA5 protein]; salubrinal inhibits the reaction [4-Quinolones analog inhibits the reaction [Glucose deficiency results in increased expression of HSPA5 protein]]; XBP1 mRNA alternative form promotes the reaction [4-Quinolones analog inhibits the reaction [Glucose deficiency results in increased expression of HSPA5 protein]]
Glucose results in decreased expression of HSPA5 mRNA
CTD PMID:12147617 PMID:16380481 PMID:17178593 PMID:21337367 PMID:21705745 PMID:24349266 PMID:25451566 PMID:30076216 PMID:31022492 NCBI chr 3:13,838,304...13,842,763
Ensembl chr 3:13,838,304...13,842,762
JBrowse link
G Hspa9 heat shock protein family A (Hsp70) member 9 increases expression
decreases expression
multiple interactions
ISO
EXP
Glucose results in increased expression of HSPA9 protein
Glucose results in decreased expression of HSPA9 protein
KU-32 compound inhibits the reaction [Glucose results in decreased expression of HSPA9 protein]
resveratrol inhibits the reaction [Glucose results in increased expression of HSPA9 protein]
CTD PMID:22413817 PMID:24218232 NCBI chr18:27,731,072...27,749,235
Ensembl chr18:27,731,072...27,749,235
JBrowse link
G Hspb1 heat shock protein family B (small) member 1 multiple interactions
increases phosphorylation
increases secretion
EXP
ISO
[Oxygen deficiency co-treated with Glucose deficiency co-treated with Oxygen] results in increased expression of HSPB1 mRNA; [Oxygen deficiency co-treated with Glucose deficiency co-treated with Oxygen] results in increased expression of HSPB1 protein; resveratrol inhibits the reaction [[Oxygen deficiency co-treated with Glucose deficiency co-treated with Oxygen] results in increased expression of HSPB1 mRNA]; resveratrol inhibits the reaction [[Oxygen deficiency co-treated with Glucose deficiency co-treated with Oxygen] results in increased expression of HSPB1 protein]
Glucose results in increased phosphorylation of HSPB1 protein
2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [Glucose results in increased phosphorylation of HSPB1 protein]; U 0126 inhibits the reaction [Glucose results in increased phosphorylation of HSPB1 protein]
Glucose deficiency results in increased secretion of HSPB1 protein
CTD PMID:23421680 PMID:24802182 PMID:25373458 NCBI chr12:23,839,390...23,841,051
Ensembl chr12:23,839,399...23,841,049
JBrowse link
G Hspd1 heat shock protein family D (Hsp60) member 1 decreases expression
multiple interactions
ISO Glucose deficiency results in decreased expression of HSPD1 protein
Nitroprusside inhibits the reaction [Glucose deficiency results in decreased expression of HSPD1 protein]
CTD PMID:17855661 NCBI chr 9:61,680,529...61,691,202
Ensembl chr 9:61,680,530...61,690,956
JBrowse link
G Hyou1 hypoxia up-regulated 1 decreases expression ISO Glucose results in decreased expression of HYOU1 mRNA CTD PMID:17178593 NCBI chr 8:48,699,796...48,711,912
Ensembl chr 8:48,699,769...48,711,910
JBrowse link
G Iapp islet amyloid polypeptide multiple interactions
increases expression
ISO
EXP
IAPP protein inhibits the reaction [Glucose results in increased secretion of INS protein]; Rosiglitazone inhibits the reaction [IAPP protein inhibits the reaction [Glucose results in increased secretion of INS protein]]
Glucose results in increased expression of IAPP mRNA
Diazoxide inhibits the reaction [Glucose results in increased expression of IAPP mRNA]; Mannoheptulose inhibits the reaction [Glucose results in increased expression of IAPP mRNA]; Verapamil inhibits the reaction [Glucose results in increased expression of IAPP mRNA]
CTD PMID:9142872 PMID:16204373 NCBI chr 4:176,509,863...176,517,903
Ensembl chr 4:176,510,696...176,516,083
JBrowse link
G Icam1 intercellular adhesion molecule 1 increases expression
increases secretion
multiple interactions
ISO
EXP
Glucose results in increased expression of ICAM1; Glucose results in increased expression of ICAM1 mRNA; Glucose results in increased expression of ICAM1 protein
Glucose results in increased secretion of ICAM1 protein
4-(4-fluorophenyl)-2-(4-hydroxyphenyl)-5-(4-pyridyl)imidazole inhibits the reaction [Glucose results in increased expression of ICAM1]; 5,21 - 12,17-dimetheneo-18H-dibenzo(i,o)pyrrolo(3,4-1)(1,8)diazacyclohexandecine-18,10(19H)dione,8((dimethylamino)methyl)-6,7,8,9,10,11-hexahydro,monomethanesulfonate inhibits the reaction [Glucose results in increased expression of ICAM1 mRNA]; 5,21 - 12,17-dimetheneo-18H-dibenzo(i,o)pyrrolo(3,4-1)(1,8)diazacyclohexandecine-18,10(19H)dione,8((dimethylamino)methyl)-6,7,8,9,10,11-hexahydro,monomethanesulfonate inhibits the reaction [Glucose results in increased expression of ICAM1 protein]; [Resveratrol affects the localization of RELA protein] inhibits the reaction [Glucose results in increased expression of ICAM1 mRNA]; [Resveratrol affects the localization of RELA protein] inhibits the reaction [Glucose results in increased expression of ICAM1 protein]; aspalathin inhibits the reaction [Glucose results in increased expression of ICAM1 protein]; bisindolylmaleimide I inhibits the reaction [Glucose results in increased expression of ICAM1 mRNA]; bisindolylmaleimide I inhibits the reaction [Glucose results in increased expression of ICAM1 protein]; Hesperidin inhibits the reaction [Glucose results in increased expression of ICAM1]; HTS 466284 inhibits the reaction [Glucose results in increased expression of ICAM1 protein]; isoangustone A inhibits the reaction [Glucose results in increased expression of ICAM1 protein]; manganese chloride inhibits the reaction [Glucose results in increased expression of ICAM1 protein]; manganese(III)-tetrakis(4-benzoic acid)porphyrin inhibits the reaction [Glucose results in increased expression of ICAM1 mRNA]; manganese(III)-tetrakis(4-benzoic acid)porphyrin inhibits the reaction [Glucose results in increased expression of ICAM1 protein]; Mannitol inhibits the reaction [Glucose results in increased expression of ICAM1 mRNA]; Mannitol inhibits the reaction [Glucose results in increased expression of ICAM1 protein]; N-(oxo-5,6-dihydrophenanthridin-2-yl)-N,N-dimethylacetamide hydrochloride inhibits the reaction [Glucose results in increased expression of ICAM1 mRNA]; N-(oxo-5,6-dihydrophenanthridin-2-yl)-N,N-dimethylacetamide hydrochloride inhibits the reaction [Glucose results in increased secretion of ICAM1 protein]; naringin inhibits the reaction [Glucose results in increased expression of ICAM1]; nothofagin inhibits the reaction [Glucose results in increased expression of ICAM1 protein]; Polyphenols inhibits the reaction [Glucose results in increased expression of ICAM1 mRNA]; Resveratrol inhibits the reaction [Glucose results in increased expression of ICAM1 mRNA]; Resveratrol inhibits the reaction [Glucose results in increased expression of ICAM1 protein]; Resveratrol inhibits the reaction [Glucose results in increased expression of ICAM1]; Rimonabant inhibits the reaction [Glucose results in increased expression of ICAM1 protein]; sarpogrelate inhibits the reaction [Glucose results in increased expression of ICAM1 protein]; Thenoyltrifluoroacetone inhibits the reaction [Glucose results in increased expression of ICAM1 mRNA]; Thenoyltrifluoroacetone inhibits the reaction [Glucose results in increased expression of ICAM1 protein]
Curcumin analog inhibits the reaction [Glucose results in increased expression of ICAM1 mRNA]; Curcumin inhibits the reaction [Glucose results in increased expression of ICAM1 mRNA]; Y 27632 inhibits the reaction [Glucose results in increased expression of ICAM1 protein]
CTD PMID:15304054 PMID:16285992 PMID:21367880 PMID:21373835 PMID:21682256 PMID:22074828 PMID:23111892 PMID:23329836 PMID:23376009 PMID:24436987 PMID:24513509 PMID:25338943 PMID:28700904 NCBI chr 8:22,035,287...22,047,049
Ensembl chr 8:22,035,256...22,047,059
JBrowse link
G Id1 inhibitor of DNA binding 1, HLH protein increases expression ISO Glucose results in increased expression of ID1 mRNA CTD PMID:17178593 NCBI chr 3:148,214,623...148,216,715
Ensembl chr 3:148,215,540...148,216,718
JBrowse link
G Id3 inhibitor of DNA binding 3, HLH protein increases expression ISO Glucose results in increased expression of ID3 mRNA CTD PMID:17178593 NCBI chr 5:154,489,603...154,491,172
Ensembl chr 5:154,489,590...154,491,223
JBrowse link
G Ide insulin degrading enzyme decreases expression ISO Glucose results in decreased expression of IDE mRNA CTD PMID:17178593 NCBI chr 1:255,914,465...256,014,168
Ensembl chr 1:255,914,447...256,013,495
JBrowse link
G Ifng interferon gamma multiple interactions ISO
EXP
[IL1B protein co-treated with IFNG protein] promotes the reaction [Glucose results in increased secretion of INS protein]
[TNF protein co-treated with IFNG protein co-treated with IL1B protein] inhibits the reaction [Glucose results in increased secretion of INS protein alternative form]; Quercetin inhibits the reaction [[TNF protein co-treated with IL1B protein co-treated with IFNG protein] inhibits the reaction [Glucose results in increased secretion of INS1 protein]]
[IL1B protein co-treated with IFNG protein] inhibits the reaction [Glucose results in increased secretion of INS1 protein]; [TNF protein co-treated with IL1B protein co-treated with IFNG protein] inhibits the reaction [Glucose results in increased secretion of INS1 protein]; quercitrin inhibits the reaction [[TNF protein co-treated with IL1B protein co-treated with IFNG protein] inhibits the reaction [Glucose results in increased secretion of INS1 protein]]; sulforaphane inhibits the reaction [[IL1B protein co-treated with IFNG protein] inhibits the reaction [Glucose results in increased secretion of INS1 protein]]
CTD PMID:10967106 PMID:19071154 PMID:23138875 PMID:31776611 NCBI chr 7:61,337,383...61,341,419
Ensembl chr 7:61,337,381...61,341,419
JBrowse link
G Igf1 insulin-like growth factor 1 increases uptake ISO IGF1 protein results in increased uptake of Glucose CTD PMID:29330302 NCBI chr 7:28,412,123...28,491,815
Ensembl chr 7:28,412,198...28,486,609
JBrowse link
G Igf1r insulin-like growth factor 1 receptor decreases expression
increases expression
multiple interactions
ISO Glucose results in decreased expression of IGF1R protein
Glucose results in increased expression of IGF1R mRNA
Berberine inhibits the reaction [Glucose results in decreased expression of IGF1R protein]
CTD PMID:7826318 PMID:23954465 NCBI chr 1:128,924,921...129,213,816
Ensembl chr 1:128,924,966...129,206,516
JBrowse link
G Igfbp4 insulin-like growth factor binding protein 4 decreases expression ISO Glucose results in decreased expression of IGFBP4 mRNA CTD PMID:17178593 NCBI chr10:86,950,555...86,962,563
Ensembl chr10:86,950,557...86,962,578
JBrowse link
G Ikbkb inhibitor of nuclear factor kappa B kinase subunit beta multiple interactions EXP
ISO
IKBKB affects the reaction [IL1B protein inhibits the reaction [Glucose results in increased expression of INS2 mRNA alternative form]]; IKBKB affects the reaction [lipopolysaccharide, Escherichia coli O111 B4 inhibits the reaction [Glucose results in increased expression of INS2 mRNA alternative form]]
IKBKB protein affects the reaction [Particulate Matter promotes the reaction [Glucose results in increased secretion of INS1 protein]]
CTD PMID:22558381 PMID:31095431 NCBI chr16:74,177,233...74,230,809
Ensembl chr16:74,177,215...74,230,815
JBrowse link
G Il12b interleukin 12B multiple interactions
increases expression
ISO 2-chloro-4'-methoxychalcone inhibits the reaction [Glucose results in increased expression of IL12B mRNA] CTD PMID:21988173 NCBI chr10:30,034,447...30,048,774
Ensembl chr10:30,038,709...30,048,085
JBrowse link
G Il17a interleukin 17A multiple interactions
increases expression
increases secretion
ISO Cycloheximide inhibits the reaction [Glucose results in increased secretion of IL17A protein]; Dactinomycin inhibits the reaction [Glucose results in increased secretion of IL17A protein]; Resveratrol inhibits the reaction [Glucose results in increased expression of IL17A mRNA]; Resveratrol inhibits the reaction [Glucose results in increased secretion of IL17A protein] CTD PMID:18310510 NCBI chr 9:26,841,299...26,844,786
Ensembl chr 9:26,841,299...26,844,786
JBrowse link
G Il17ra interleukin 17 receptor A increases expression ISO Glucose results in increased expression of IL17RA mRNA CTD PMID:18310510 NCBI chr 4:152,995,865...153,018,394
Ensembl chr 4:152,995,865...153,018,394
JBrowse link
G Il1b interleukin 1 beta multiple interactions
increases secretion
increases expression
ISO
EXP
2-chloro-4'-methoxychalcone inhibits the reaction [Glucose results in increased expression of IL1B mRNA]; [cobaltiprotoporphyrin co-treated with IL1B protein] affects the susceptibility to Glucose; [Glucose co-treated with lipopolysaccharide, Escherichia coli O111 B4] results in increased secretion of IL1B protein; [IL1B protein co-treated with IFNG protein] promotes the reaction [Glucose results in increased secretion of INS protein]; Acetylcysteine inhibits the reaction [Glucose results in increased expression of IL1B protein]; Glucose inhibits the reaction [IL1B protein results in increased expression of MMP1 mRNA]; Glucose inhibits the reaction [IL1B protein results in increased expression of MMP1 protein]; Glucose inhibits the reaction [IL1B protein results in increased phosphorylation of JUN protein]; Glucose inhibits the reaction [IL1B protein results in increased phosphorylation of MAPK1 protein]; Glucose inhibits the reaction [IL1B protein results in increased phosphorylation of MAPK3 protein]; Glucose inhibits the reaction [IL1B protein results in increased phosphorylation of PTK2 protein]; IL1B protein inhibits the reaction [Glucose results in increased expression of INS2 mRNA alternative form]; IL1B protein inhibits the reaction [Glucose results in increased expression of MAFA mRNA]; IL1B protein inhibits the reaction [Glucose results in increased expression of PDX1 mRNA]; Silymarin inhibits the reaction [[Glucose co-treated with lipopolysaccharide, Escherichia coli O111 B4] results in increased secretion of IL1B protein]
Glucose results in increased secretion of IL1B protein
Glucose results in increased expression of IL1B mRNA; Glucose results in increased expression of IL1B protein
[Carnosine co-treated with asiatic acid] inhibits the reaction [Glucose results in increased secretion of IL1B protein]; [Glucose co-treated with Lipopolysaccharides] results in decreased expression of IL1B protein; [Glucose co-treated with Pam(3)CSK(4) peptide] results in decreased expression of IL1B protein; [TNF protein co-treated with IFNG protein co-treated with IL1B protein] inhibits the reaction [Glucose results in increased secretion of INS protein alternative form]; Allopurinol inhibits the reaction [Glucose results in increased expression of IL1B protein]; asiatic acid inhibits the reaction [Glucose results in increased secretion of IL1B protein]; Carnosine inhibits the reaction [Glucose results in increased secretion of IL1B protein]; Catechin inhibits the reaction [Glucose results in increased expression of IL1B mRNA]; Catechin inhibits the reaction [Glucose results in increased expression of IL1B protein]; epigallocatechin gallate inhibits the reaction [Glucose results in increased expression of IL1B mRNA]; epigallocatechin gallate inhibits the reaction [Glucose results in increased expression of IL1B protein]; Glucose promotes the reaction [Particulate Matter results in increased expression of IL1B mRNA]; Luteolin inhibits the reaction [Glucose results in increased expression of IL1B mRNA]; Luteolin inhibits the reaction [Glucose results in increased expression of IL1B protein]; MIR217 mRNA inhibits the reaction [Glucose results in increased secretion of IL1B protein]; Quercetin inhibits the reaction [[TNF protein co-treated with IL1B protein co-treated with IFNG protein] inhibits the reaction [Glucose results in increased secretion of INS1 protein]]; Quercetin inhibits the reaction [Glucose results in increased expression of IL1B mRNA]; Quercetin inhibits the reaction [Glucose results in increased expression of IL1B protein]; Rutin inhibits the reaction [Glucose results in increased expression of IL1B mRNA]; Rutin inhibits the reaction [Glucose results in increased expression of IL1B protein]
[IL1B protein co-treated with IFNG protein] inhibits the reaction [Glucose results in increased secretion of INS1 protein]; [Oxygen deficiency co-treated with Glucose deficiency] results in increased expression of IL1B protein; [TNF protein co-treated with IL1B protein co-treated with IFNG protein] inhibits the reaction [Glucose results in increased secretion of INS1 protein]; Allopurinol inhibits the reaction [Glucose results in increased expression of IL1B protein]; Artesunate inhibits the reaction [Glucose results in increased expression of IL1B mRNA]; Artesunate inhibits the reaction [Glucose results in increased secretion of IL1B protein]; Ellagic Acid inhibits the reaction [Glucose results in increased expression of IL1B protein]; ethyl 6-(N-(2-chloro-4-fluorophenyl)sulfamoyl)cyclohex-1-ene-1-carboxylate inhibits the reaction [Glucose results in increased secretion of IL1B protein]; farrerol inhibits the reaction [Glucose results in increased expression of IL1B mRNA]; farrerol inhibits the reaction [Glucose results in increased secretion of IL1B protein]; Gallic Acid inhibits the reaction [Glucose results in increased secretion of IL1B protein]; IKBKB affects the reaction [IL1B protein inhibits the reaction [Glucose results in increased expression of INS2 mRNA alternative form]]; IL1B protein inhibits the reaction [Glucose results in increased abundance of Proteoglycans]; IL1B protein inhibits the reaction [Glucose results in increased expression of B3GAT3 mRNA]; IL1B protein inhibits the reaction [Glucose results in increased expression of INS2 mRNA alternative form]; prolinedithiocarbamate inhibits the reaction [Glucose results in increased secretion of IL1B protein]; Quercetin inhibits the reaction [Glucose results in increased expression of IL1B protein]; quercitrin inhibits the reaction [[TNF protein co-treated with IL1B protein co-treated with IFNG protein] inhibits the reaction [Glucose results in increased secretion of INS1 protein]]; sulforaphane inhibits the reaction [[IL1B protein co-treated with IFNG protein] inhibits the reaction [Glucose results in increased secretion of INS1 protein]]; trigonelline inhibits the reaction [[Oxygen deficiency co-treated with Glucose deficiency] results in increased expression of IL1B protein]
CTD PMID:10967106 PMID:11801247 PMID:15194409 PMID:19071154 PMID:19557821 PMID:19861503 PMID:20200188 PMID:21988173 PMID:22558381 PMID:23138875 PMID:23647015 PMID:24877639 PMID:26179980 PMID:26341651 PMID:27783111 PMID:29753610 PMID:30031708 PMID:30098273 PMID:30802477 PMID:31776611 PMID:31838053 PMID:31935362 PMID:33283391 NCBI chr 3:121,876,256...121,882,637
Ensembl chr 3:121,876,263...121,882,726
JBrowse link
G Il1rn interleukin 1 receptor antagonist multiple interactions EXP IL1RN protein inhibits the reaction [Glucose results in increased expression of PTGS2 mRNA]; IL1RN protein inhibits the reaction [Glucose results in increased expression of PTGS2 protein] CTD PMID:19861503 NCBI chr 3:1,449,778...1,468,624
Ensembl chr 3:1,452,644...1,468,614
JBrowse link
G Il23r interleukin 23 receptor decreases expression ISO Glucose results in decreased expression of IL23R mRNA CTD PMID:31525975 NCBI chr 4:98,203,788...98,306,729
Ensembl chr 4:98,203,958...98,305,173
JBrowse link
G Il24 interleukin 24 increases expression ISO Glucose results in increased expression of IL24 mRNA CTD PMID:17178593 NCBI chr13:47,618,451...47,623,849
Ensembl chr13:47,618,452...47,623,849
JBrowse link
G Il6 interleukin 6 multiple interactions
increases expression
increases secretion
ISO
EXP
[Carnosine co-treated with asiatic acid] inhibits the reaction [Glucose results in increased secretion of IL6 protein]; asiatic acid inhibits the reaction [Glucose results in increased secretion of IL6 protein]; Carnosine inhibits the reaction [Glucose results in increased secretion of IL6 protein]; chromic chloride inhibits the reaction [Glucose results in increased secretion of IL6 protein]; chromic chloride promotes the reaction [Estradiol inhibits the reaction [Glucose results in increased secretion of IL6 protein]]; chromium nicotinic acid complex inhibits the reaction [Glucose results in increased secretion of IL6 protein]; Estradiol inhibits the reaction [Glucose results in increased secretion of IL6 protein]; Glucose results in increased secretion of and results in increased expression of IL6 protein; MIR217 mRNA inhibits the reaction [Glucose results in increased secretion of IL6 protein]; N-(oxo-5,6-dihydrophenanthridin-2-yl)-N,N-dimethylacetamide hydrochloride inhibits the reaction [Glucose results in increased expression of IL6 mRNA]; N-(oxo-5,6-dihydrophenanthridin-2-yl)-N,N-dimethylacetamide hydrochloride inhibits the reaction [Glucose results in increased secretion of IL6 protein]; picolinic acid inhibits the reaction [Glucose results in increased secretion of IL6 protein]; Polyphenols inhibits the reaction [Glucose results in increased expression of IL6 mRNA]; Polyphenols inhibits the reaction [Glucose results in increased expression of IL6 protein]; Resveratrol inhibits the reaction [Glucose results in increased expression of IL6 mRNA]; Resveratrol inhibits the reaction [Glucose results in increased expression of IL6 protein]
3,3',4,5'-tetrahydroxystilbene inhibits the reaction [Glucose results in increased expression of IL6 mRNA]; [Oxygen deficiency co-treated with Glucose deficiency co-treated with Oxygen] results in increased expression of and results in increased secretion of IL6 protein; [Oxygen deficiency co-treated with Glucose deficiency co-treated with Oxygen] results in increased expression of IL6 mRNA; [Oxygen deficiency co-treated with Glucose deficiency] results in increased expression of IL6 mRNA; [Oxygen deficiency co-treated with Glucose deficiency] results in increased expression of IL6 protein; Artesunate inhibits the reaction [Glucose results in increased expression of IL6 mRNA]; Artesunate inhibits the reaction [Glucose results in increased secretion of IL6 protein]; Curcumin analog inhibits the reaction [Glucose results in increased expression of IL6 mRNA]; duanbanhuain A inhibits the reaction [Glucose results in increased secretion of IL6 protein]; duanbanhuain B inhibits the reaction [Glucose results in increased secretion of IL6 protein]; Ellagic Acid inhibits the reaction [Glucose results in increased expression of IL6 protein]; ethyl 6-(N-(2-chloro-4-fluorophenyl)sulfamoyl)cyclohex-1-ene-1-carboxylate inhibits the reaction [Glucose results in increased secretion of IL6 protein]; farrerol inhibits the reaction [Glucose results in increased expression of IL6 mRNA]; farrerol inhibits the reaction [Glucose results in increased secretion of IL6 protein]; Gallic Acid inhibits the reaction [Glucose results in increased secretion of IL6 protein]; Oxygen promotes the reaction [[Oxygen deficiency co-treated with Glucose deficiency] results in increased expression of IL6 mRNA]; prolinedithiocarbamate inhibits the reaction [Glucose results in increased secretion of IL6 protein]; Quercetin inhibits the reaction [Glucose results in increased expression of IL6 mRNA]; Quercetin inhibits the reaction [Glucose results in increased expression of IL6 protein]; Resveratrol inhibits the reaction [[Oxygen deficiency co-treated with Glucose deficiency co-treated with Oxygen] results in increased expression of IL6 mRNA]; Resveratrol inhibits the reaction [[Oxygen deficiency co-treated with Glucose deficiency co-treated with Oxygen] results in increased secretion of IL6 protein]; trigonelline inhibits the reaction [[Oxygen deficiency co-treated with Glucose deficiency] results in increased expression of IL6 protein]
Glucose results in increased expression of IL6 mRNA; Glucose results in increased expression of IL6 protein
2-chloro-4'-methoxychalcone inhibits the reaction [Glucose results in increased expression of IL6 mRNA]; [Glucose co-treated with lipopolysaccharide, Escherichia coli O111 B4] results in increased secretion of IL6 protein; IL6 protein inhibits the reaction [[[Oxygen deficiency co-treated with Glucose deficiency] co-treated with Oxygen] inhibits the reaction [IL6RA protein binds to IL6ST protein]]; IL6 protein inhibits the reaction [[[Oxygen deficiency co-treated with Glucose deficiency] co-treated with Oxygen] results in decreased expression of SOD2 protein]; IL6 protein inhibits the reaction [[[Oxygen deficiency co-treated with Glucose deficiency] co-treated with Oxygen] results in decreased phosphorylation of STAT3 protein]; Silymarin inhibits the reaction [[Glucose co-treated with lipopolysaccharide, Escherichia coli O111 B4] results in increased secretion of IL6 protein]
CTD PMID:11108930 PMID:15304054 PMID:15528032 PMID:17665966 PMID:20578705 PMID:21682256 PMID:21940958 PMID:21988173 PMID:22036992 PMID:23770986 PMID:24877639 PMID:26341651 PMID:27049278 PMID:28700904 PMID:29753610 PMID:30031708 PMID:30802477 PMID:31323227 PMID:31838053 PMID:31935362 PMID:33283391 NCBI chr 4:3,043,231...3,047,807
Ensembl chr 4:3,043,231...3,047,807
JBrowse link
G Il6r interleukin 6 receptor multiple interactions ISO [[[Oxygen deficiency co-treated with Glucose deficiency] co-treated with Oxygen] inhibits the reaction [IL6RA protein binds to IL6ST protein]] promotes the reaction [IL6ST protein binds to and results in increased phosphorylation of STAT3 protein]; [[Oxygen deficiency co-treated with Glucose deficiency] co-treated with Oxygen] inhibits the reaction [IL6RA protein binds to IL6ST protein]; [[Oxygen deficiency co-treated with Glucose deficiency] co-treated with Oxygen] results in increased oxidation of IL6RA protein; IL6 protein inhibits the reaction [[[Oxygen deficiency co-treated with Glucose deficiency] co-treated with Oxygen] inhibits the reaction [IL6RA protein binds to IL6ST protein]] CTD PMID:21940958 NCBI chr 2:189,196,180...189,255,987
Ensembl chr 2:189,205,701...189,254,628
JBrowse link
G Il6st interleukin 6 cytokine family signal transducer multiple interactions ISO [[[Oxygen deficiency co-treated with Glucose deficiency] co-treated with Oxygen] inhibits the reaction [IL6RA protein binds to IL6ST protein]] promotes the reaction [IL6ST protein binds to and results in increased phosphorylation of STAT3 protein]; [[Oxygen deficiency co-treated with Glucose deficiency] co-treated with Oxygen] inhibits the reaction [IL6RA protein binds to IL6ST protein]; [[Oxygen deficiency co-treated with Glucose deficiency] co-treated with Oxygen] results in increased oxidation of IL6ST protein; IL6 protein inhibits the reaction [[[Oxygen deficiency co-treated with Glucose deficiency] co-treated with Oxygen] inhibits the reaction [IL6RA protein binds to IL6ST protein]] CTD PMID:21940958 NCBI chr 2:44,279,199...44,319,427
Ensembl chr 2:44,289,393...44,314,944
JBrowse link
G Ins2 insulin 2 multiple interactions
affects response to substance
increases uptake
increases expression
increases secretion
decreases expression
decreases secretion
decreases chemical synthesis
increases activity
ISO
EXP
15-deoxy-delta(12,14)-prostaglandin J2 inhibits the reaction [Fatty Acids, Nonesterified inhibits the reaction [INS protein results in increased secretion of Glucose]]; 3,4-dihydro-5-methyl-1(2H)-isoquinolinone inhibits the reaction [Glucose inhibits the reaction [MAFA protein binds to INS promoter]]; 3,4-dihydro-5-methyl-1(2H)-isoquinolinone inhibits the reaction [Glucose results in increased expression of INS mRNA]; 3,4-dihydro-5-methyl-1(2H)-isoquinolinone inhibits the reaction [Glucose results in increased expression of INS protein]; 3-aminobenzamide inhibits the reaction [Glucose inhibits the reaction [MAFA protein binds to INS promoter]]; 3-aminobenzamide inhibits the reaction [Glucose results in increased expression of INS mRNA]; 3-aminobenzamide inhibits the reaction [Glucose results in increased expression of INS protein]; 6-chloro-2,3,4,9-tetrahydro-1H-carbazole-1-carboxamide inhibits the reaction [SIRT1 protein inhibits the reaction [Resveratrol promotes the reaction [Glucose results in increased secretion of INS protein]]]; [6alpha-ethyl-23(S)-methylcholic acid co-treated with Glucose] results in increased secretion of INS protein; [Cadmium Chloride results in increased abundance of Cadmium] inhibits the reaction [Glucose results in increased secretion of INS protein]; [chromic chloride results in increased activity of INS protein modified form] which results in increased import of Glucose; [Glucose affects the susceptibility to INS protein] which affects the phosphorylation of AKT1 protein; [Glucose affects the susceptibility to INS protein] which affects the uptake of Glucose; [Glucose co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with INS1 protein] results in increased expression of ADIPOQ mRNA; [Glucose co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with INS1 protein] results in increased expression of ADIPOQ protein; [Glucose co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with INS1 protein] results in increased expression of FABP4 mRNA; [Glucose co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with INS1 protein] results in increased expression of PPARG mRNA; [Glucose co-treated with INS protein] affects the localization of PDX1 protein; [Glucose co-treated with sodium arsenite] results in increased secretion of INS protein; [Glyburide co-treated with Glucose] results in increased expression of INS protein; [INS protein co-treated with Glucose] results in decreased chemical synthesis of Nitric Oxide; [INS protein co-treated with Glucose] results in decreased expression of SLC2A3 protein; [INS protein co-treated with Glucose] results in increased expression of ACACA mRNA; [INS protein co-treated with Glucose] results in increased expression of FASN mRNA; [INS protein co-treated with Glucose] results in increased expression of SREBF1 mRNA; [Lithocholic Acid co-treated with Glucose] results in increased secretion of INS protein; [manganese chloride results in increased abundance of Manganese] inhibits the reaction [Glucose results in increased secretion of INS protein]; [Oleanolic Acid co-treated with Glucose] results in increased secretion of INS protein; [SB 203580 co-treated with INS protein] inhibits the reaction [Glucose affects the localization of PDX1 protein]; [sodium arsenite results in increased abundance of arsenite] inhibits the reaction [Glucose results in increased secretion of INS protein]; [TNF protein co-treated with IFNG protein co-treated with IL1B protein] inhibits the reaction [Glucose results in increased secretion of INS protein alternative form]; [Wortmannin co-treated with INS protein] inhibits the reaction [Glucose affects the localization of PDX1 protein]; Acetylcysteine inhibits the reaction [Glucose results in increased expression of INS protein]; Acetylcysteine inhibits the reaction [tributyltin promotes the reaction [Glucose results in increased secretion of INS protein]]; alpha-pentyl-3-(2-quinolinylmethoxy)benzenemethanol promotes the reaction [Glucose results in increased secretion of INS protein]; Arachidonic Acid promotes the reaction [Glucose results in increased secretion of INS protein]; arachidonyltrifluoromethane inhibits the reaction [Glucose results in increased secretion of INS protein]; avobenzone promotes the reaction [[Glucose co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with INS1 protein] results in increased expression of ADIPOQ mRNA]; avobenzone promotes the reaction [[Glucose co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with INS1 protein] results in increased expression of ADIPOQ protein]; avobenzone promotes the reaction [[Glucose co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with INS1 protein] results in increased expression of FABP4 mRNA]; avobenzone promotes the reaction [[Glucose co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with INS1 protein] results in increased expression of PPARG mRNA]; baicalein promotes the reaction [Glucose results in increased secretion of INS protein]; bisphenol A inhibits the reaction [INS1 protein results in increased uptake of Glucose]; butylbenzyl phthalate promotes the reaction [[Glucose co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with INS1 protein] results in increased expression of ADIPOQ protein]; Chlorpropamide inhibits the reaction [Glucose results in decreased secretion of INS protein]; Dexamethasone inhibits the reaction [Glucose results in increased secretion of INS protein]; Dexamethasone inhibits the reaction [INS protein results in increased uptake of Glucose]; Diethylhexyl Phthalate promotes the reaction [[Glucose co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with INS1 protein] results in increased expression of ADIPOQ protein]; dioxybenzone promotes the reaction [[Glucose co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with INS1 protein] results in increased expression of ADIPOQ mRNA]; dioxybenzone promotes the reaction [[Glucose co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with INS1 protein] results in increased expression of ADIPOQ protein]; dioxybenzone promotes the reaction [[Glucose co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with INS1 protein] results in increased expression of FABP4 mRNA]; dioxybenzone promotes the reaction [[Glucose co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with INS1 protein] results in increased expression of PPARG mRNA]; Enalaprilat inhibits the reaction [Glucose results in decreased secretion of INS protein]; Exenatide inhibits the reaction [Tetrachlorodibenzodioxin inhibits the reaction [Glucose results in increased secretion of INS protein alternative form]]; Fatty Acids, Nonesterified inhibits the reaction [INS protein results in increased secretion of Glucose]; Fulvestrant inhibits the reaction [tributyltin promotes the reaction [Glucose results in increased secretion of INS protein]]; fumosorinone promotes the reaction [INS protein results in increased uptake of Glucose]; Glucose inhibits the reaction [INS protein results in increased chemical synthesis of Glycogen]; Glucose inhibits the reaction [INS protein results in increased phosphorylation of AKT1 protein]; Glucose inhibits the reaction [INS protein results in increased phosphorylation of GSK3B protein]; Glucose inhibits the reaction [INS protein results in increased phosphorylation of INSR protein]; Glucose inhibits the reaction [INS protein results in increased secretion of Nitric Oxide]; Glyburide inhibits the reaction [Glucose results in decreased secretion of INS protein]; GW8510 promotes the reaction [Glucose results in increased secretion of INS protein]; IAPP protein inhibits the reaction [Glucose results in increased secretion of INS protein]; INS protein inhibits the reaction [Glucose results in decreased expression of ATP1A1 protein]; INS protein mutant form results in decreased uptake of and results in decreased oxidation of Glucose; IRS1 protein polymorphism inhibits the reaction [Glucose results in increased secretion of INS protein]; Kynurenic Acid inhibits the reaction [[INS protein co-treated with Glucose] results in decreased chemical synthesis of Nitric Oxide]; Kynurenic Acid inhibits the reaction [[INS protein co-treated with Glucose] results in decreased expression of SLC2A3 protein]; mercaptosteroid 6 inhibits the reaction [Glucose results in increased secretion of INS protein]; Metformin inhibits the reaction [[Glucose affects the susceptibility to INS protein] which affects the uptake of Glucose]; Metformin promotes the reaction [Glucose results in increased secretion of INS protein]; methylarsine oxide inhibits the reaction [Glucose results in increased secretion of INS protein]; Methylcholanthrene promotes the reaction [Glucose results in increased secretion of INS protein alternative form]; MIR133A1 affects the reaction [Glucose results in decreased chemical synthesis of INS protein]; N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide promotes the reaction [Glucose results in increased secretion of INS protein]; N-(oxo-5,6-dihydrophenanthridin-2-yl)-N,N-dimethylacetamide hydrochloride inhibits the reaction [Glucose inhibits the reaction [INS protein results in increased phosphorylation of AKT1 protein]]; N-(oxo-5,6-dihydrophenanthridin-2-yl)-N,N-dimethylacetamide hydrochloride inhibits the reaction [Glucose inhibits the reaction [INS protein results in increased phosphorylation of GSK3B protein]]; N-(oxo-5,6-dihydrophenanthridin-2-yl)-N,N-dimethylacetamide hydrochloride inhibits the reaction [Glucose inhibits the reaction [INS protein results in increased phosphorylation of INSR protein]]; Niacinamide inhibits the reaction [Glucose inhibits the reaction [MAFA protein binds to INS promoter]]; Niacinamide inhibits the reaction [Glucose results in increased expression of INS mRNA]; Niacinamide inhibits the reaction [Glucose results in increased expression of INS protein]; NKX6-1 protein promotes the reaction [Glucose results in increased secretion of INS protein]; oxybenzone promotes the reaction [[Glucose co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with INS1 protein] results in increased expression of ADIPOQ mRNA]; oxybenzone promotes the reaction [[Glucose co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with INS1 protein] results in increased expression of ADIPOQ protein]; oxybenzone promotes the reaction [[Glucose co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with INS1 protein] results in increased expression of FABP4 mRNA]; oxybenzone promotes the reaction [[Glucose co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with INS1 protein] results in increased expression of PPARG mRNA]; palmitoyl trifluoromethyl ketone inhibits the reaction [Glucose results in increased secretion of INS protein]; PARP1 protein affects the reaction [Glucose inhibits the reaction [INS protein results in increased phosphorylation of INSR protein]]; Pioglitazone promotes the reaction [[Glucose co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with INS1 protein] results in increased expression of ADIPOQ protein]; Plant Extracts inhibits the reaction [[Glucose affects the susceptibility to INS protein] which affects the uptake of Glucose]; pyrazolanthrone inhibits the reaction [bisphenol A inhibits the reaction [INS1 protein results in increased uptake of Glucose]]; Quercetin inhibits the reaction [[TNF protein co-treated with IL1B protein co-treated with IFNG protein] inhibits the reaction [Glucose results in increased secretion of INS1 protein]]; Quercetin inhibits the reaction [Glucose results in increased expression of INS protein]; Resveratrol inhibits the reaction [Glucose inhibits the reaction [INS protein results in increased secretion of Nitric Oxide]]; Resveratrol promotes the reaction [Glucose results in increased secretion of INS protein]; Ro 32-0432 inhibits the reaction [tributyltin promotes the reaction [Glucose results in increased secretion of INS protein]]; Rosiglitazone inhibits the reaction [Fatty Acids, Nonesterified inhibits the reaction [INS protein results in increased secretion of Glucose]]; Rosiglitazone inhibits the reaction [IAPP protein inhibits the reaction [Glucose results in increased secretion of INS protein]]; Rosiglitazone promotes the reaction [INS protein results in increased uptake of Glucose]; Saquinavir inhibits the reaction [INS protein results in increased import of Glucose]; SIRT1 protein affects the reaction [Resveratrol inhibits the reaction [Glucose inhibits the reaction [INS protein results in increased secretion of Nitric Oxide]]]; SIRT1 protein inhibits the reaction [Resveratrol promotes the reaction [Glucose results in increased secretion of INS protein]]; SLC30A8 protein promotes the reaction [Glucose results in increased secretion of INS protein]; sodium arsenite inhibits the reaction [Glucose results in increased secretion of INS protein]; sodium arsenite inhibits the reaction [INS protein results in increased uptake of Glucose]; SRT1720 inhibits the reaction [[INS protein co-treated with Glucose] results in increased expression of ACACA mRNA]; SRT1720 inhibits the reaction [[INS protein co-treated with Glucose] results in increased expression of FASN mRNA]; SRT1720 inhibits the reaction [[INS protein co-treated with Glucose] results in increased expression of SREBF1 mRNA]; Tetrachlorodibenzodioxin inhibits the reaction [Glucose results in increased secretion of INS protein alternative form]; Thapsigargin inhibits the reaction [Glucose results in increased secretion of INS protein alternative form]; Thioctic Acid inhibits the reaction [Glucose results in increased expression of INS protein]; TNF protein inhibits the reaction [INS protein results in increased uptake of Glucose]; TPH1 protein affects the reaction [Glucose results in increased secretion of INS protein]; TPH1 protein affects the reaction [sodium arsenite inhibits the reaction [Glucose results in increased secretion of INS protein]]; TPH1 protein affects the reaction [UGT1A6A protein affects the reaction [sodium arsenite inhibits the reaction [Glucose results in increased secretion of INS protein]]]; tributyltin promotes the reaction [[Glucose co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with INS1 protein] results in increased expression of ADIPOQ protein]; tributyltin promotes the reaction [Glucose results in increased secretion of INS protein]; Troglitazone inhibits the reaction [TNF protein inhibits the reaction [INS protein results in increased uptake of Glucose]]; UCP3 protein promotes the reaction [Glucose results in increased secretion of INS protein]; UGT1A6A protein affects the reaction [sodium arsenite inhibits the reaction [Glucose results in increased secretion of INS protein]]
Acetylcysteine inhibits the reaction [Dexamethasone inhibits the reaction [Glucose results in increased secretion of INS protein]]; Dexamethasone inhibits the reaction [Glucose results in increased secretion of INS protein]; IKBKB affects the reaction [IL1B protein inhibits the reaction [Glucose results in increased expression of INS2 mRNA alternative form]]; IKBKB affects the reaction [lipopolysaccharide, Escherichia coli O111 B4 inhibits the reaction [Glucose results in increased expression of INS2 mRNA alternative form]]; IL1B protein inhibits the reaction [Glucose results in increased expression of INS2 mRNA alternative form]; lipopolysaccharide, Escherichia coli O111 B4 inhibits the reaction [Glucose results in increased expression of INS2 mRNA alternative form]; Quercetin inhibits the reaction [INS protein results in increased uptake of Glucose]
Glucose results in increased expression of INS mRNA; Glucose results in increased expression of INS2 mRNA alternative form
2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [triphenyl phosphate promotes the reaction [INS protein results in increased import of Glucose]]; 3,4,3',4'-tetrachlorobiphenyl inhibits the reaction [INS protein results in increased uptake of Glucose]; [IL1B protein co-treated with IFNG protein] promotes the reaction [Glucose results in increased secretion of INS protein]; bisphenol A promotes the reaction [Glucose results in increased secretion of INS protein]; Estradiol promotes the reaction [Glucose results in increased secretion of INS2 protein]; IL1B protein inhibits the reaction [Glucose results in increased expression of INS2 mRNA alternative form]; lipopolysaccharide, Escherichia coli O111 B4 inhibits the reaction [Glucose results in increased expression of INS2 mRNA alternative form]; MIR338 mRNA affects the reaction [Glucose results in increased secretion of INS protein]; Palmitic Acid inhibits the reaction [Glucose results in increased expression of INS2 mRNA alternative form]; PDX1 protein affects the reaction [bisphenol A promotes the reaction [Glucose results in increased secretion of INS protein]]; perfluorooctane sulfonic acid promotes the reaction [INS protein results in increased uptake of Glucose]; Resveratrol inhibits the reaction [3,4,3',4'-tetrachlorobiphenyl inhibits the reaction [INS protein results in increased uptake of Glucose]]; TLR4 affects the reaction [lipopolysaccharide, Escherichia coli O111 B4 inhibits the reaction [Glucose results in increased expression of INS2 mRNA alternative form]]; triphenyl phosphate promotes the reaction [INS protein results in increased import of Glucose]
Glucose results in increased secretion of INS protein; Glucose results in increased secretion of INS2 protein
Glucose results in decreased expression of INS2 mRNA
Glucose results in increased secretion of INS protein; Glucose results in increased secretion of INS protein alternative form; INS protein results in increased secretion of Glucose
Glucose results in increased activity of INS promoter
CTD PMID:838844 PMID:3511099 PMID:7956951 PMID:8725009 PMID:9032110 PMID:9142872 PMID:10430617 PMID:10967106 PMID:11305519 PMID:11574405 PMID:11786383 PMID:12914525 PMID:14625208 PMID:15153144 PMID:15277403 PMID:15531508 PMID:15642492 PMID:15864539 PMID:16204373 PMID:16452552 PMID:16489446 PMID:16505238 PMID:16984975 PMID:17192482 PMID:17965850 PMID:18167556 PMID:18266981 PMID:18328801 PMID:18347054 PMID:18446233 PMID:19188863 PMID:19531641 PMID:19724016 PMID:20100676 PMID:20520763 PMID:20960276 PMID:21031461 PMID:21163946 PMID:21888768 PMID:22162761 PMID:22242153 PMID:22558381 PMID:23022524 PMID:23138875 PMID:24231106 PMID:24349194 PMID:24651439 PMID:25796170 PMID:25851902 PMID:26548598 PMID:28163246 PMID:28180948 PMID:28774890 PMID:28951307 PMID:29330302 PMID:29526746 PMID:30562058 PMID:30914352 PMID:31555879 PMID:31776611 PMID:32407875 NCBI chr 1:215,856,967...215,858,034
Ensembl chr 1:215,856,971...215,858,034
JBrowse link
G Insr insulin receptor increases phosphorylation
multiple interactions
decreases expression
decreases degradation
increases expression
ISO
EXP
Glucose results in increased phosphorylation of INSR protein
3,4-Dihydroxyphenylacetic Acid inhibits the reaction [Glucose results in decreased expression of and results in decreased phosphorylation of INSR protein]; Catechin inhibits the reaction [Glucose results in decreased expression of and results in decreased phosphorylation of INSR protein]; Glucose results in decreased expression of and results in decreased phosphorylation of INSR protein
Glucose results in decreased expression of INSR protein; Glucose results in decreased expression of INSR protein modified form
Catechin inhibits the reaction [Glucose results in decreased expression of INSR protein modified form]; Catechin inhibits the reaction [Glucose results in decreased expression of INSR protein]; Glucose inhibits the reaction [INS protein results in increased phosphorylation of INSR protein]; N-(oxo-5,6-dihydrophenanthridin-2-yl)-N,N-dimethylacetamide hydrochloride inhibits the reaction [Glucose inhibits the reaction [INS protein results in increased phosphorylation of INSR protein]]; PARP1 protein affects the reaction [Glucose inhibits the reaction [INS protein results in increased phosphorylation of INSR protein]]; Plant Extracts inhibits the reaction [Glucose results in decreased expression of INSR protein modified form]; Plant Extracts inhibits the reaction [Glucose results in decreased expression of INSR protein]
Glucose results in decreased degradation of INSR mRNA
Glucose results in increased expression of INSR mRNA
CTD PMID:7826318 PMID:21031461 PMID:24262486 PMID:29981789 NCBI chr12:1,682,527...1,816,414
Ensembl chr12:1,680,957...1,816,414
JBrowse link
G Insyn2a inhibitory synaptic factor 2A increases expression ISO Glucose results in increased expression of INSYN2A mRNA CTD PMID:31525975 NCBI chr 1:207,116,698...207,171,885
Ensembl chr 1:207,116,717...207,171,760
JBrowse link
G Ireb2 iron responsive element binding protein 2 multiple interactions EXP [Oxygen deficiency co-treated with Glucose deficiency] results in increased activity of IREB2 protein; Deferoxamine inhibits the reaction [[Oxygen deficiency co-treated with Glucose deficiency] results in increased activity of IREB2 protein] CTD PMID:16135072 NCBI chr 8:59,450,974...59,503,634
Ensembl chr 8:59,420,123...59,501,118
JBrowse link
G Irs1 insulin receptor substrate 1 multiple interactions
decreases expression
increases phosphorylation
ISO Catechin inhibits the reaction [Glucose results in decreased expression of IRS1 protein modified form]; Catechin inhibits the reaction [Glucose results in decreased expression of IRS1 protein]; Glucose promotes the reaction [PIK3R1 protein binds to IRS1 protein]; IRS1 protein polymorphism inhibits the reaction [Glucose results in increased secretion of INS protein]; Plant Extracts inhibits the reaction [Glucose results in decreased expression of IRS1 protein modified form]; Plant Extracts inhibits the reaction [Glucose results in decreased expression of IRS1 protein]
Glucose results in decreased expression of IRS1 protein; Glucose results in decreased expression of IRS1 protein modified form
Glucose results in increased phosphorylation of IRS1 protein
CTD PMID:10430617 PMID:24262486 NCBI chr 9:88,033,668...88,086,488
Ensembl chr 9:88,033,668...88,086,488
JBrowse link
G Irs2 insulin receptor substrate 2 increases phosphorylation
decreases expression
multiple interactions
increases abundance
ISO Glucose results in increased phosphorylation of IRS2 protein
Glucose results in decreased expression of IRS2 protein; Glucose results in decreased expression of IRS2 protein modified form
Catechin inhibits the reaction [Glucose results in decreased expression of IRS2 protein modified form]; Catechin inhibits the reaction [Glucose results in decreased expression of IRS2 protein]; Plant Extracts inhibits the reaction [Glucose results in decreased expression of IRS2 protein modified form]; Plant Extracts inhibits the reaction [Glucose results in decreased expression of IRS2 protein]
IRS2 gene mutant form results in increased abundance of Glucose
CTD PMID:10430617 PMID:20028942 PMID:24262486 NCBI chr16:83,824,515...83,848,569
Ensembl chr16:83,824,430...83,848,684
JBrowse link
G Islr2 immunoglobulin superfamily containing leucine-rich repeat 2 increases expression ISO Glucose results in increased expression of ISLR2 mRNA CTD PMID:31525975 NCBI chr 8:62,983,333...62,991,401
Ensembl chr 8:62,984,552...62,987,182
JBrowse link
G Itga2b integrin subunit alpha 2b multiple interactions ISO Glucose inhibits the reaction [Aspirin inhibits the reaction [Arachidonic Acid results in increased expression of ITGA2B protein]] CTD PMID:18413191 NCBI chr10:90,397,960...90,416,550
Ensembl chr10:90,398,132...90,415,070
JBrowse link
G Itga3 integrin subunit alpha 3 decreases expression
multiple interactions
ISO Glucose results in decreased expression of ITGA3 mRNA; Glucose results in decreased expression of ITGA3 protein
notoginsenoside R1 inhibits the reaction [Glucose results in decreased expression of ITGA3 mRNA]; notoginsenoside R1 inhibits the reaction [Glucose results in decreased expression of ITGA3 protein]
CTD PMID:25503068 NCBI chr10:82,855,841...82,887,755
Ensembl chr10:82,855,613...82,887,497
JBrowse link
G Itga5 integrin subunit alpha 5 decreases expression ISO Glucose results in decreased expression of ITGA5 mRNA CTD PMID:31655124 NCBI chr 7:144,970,444...144,993,652
Ensembl chr 7:144,970,444...144,993,652
JBrowse link
G Itgav integrin subunit alpha V decreases expression ISO Glucose results in decreased expression of ITGAV mRNA CTD PMID:31655124 NCBI chr 3:71,113,269...71,205,958
Ensembl chr 3:71,114,100...71,202,411
JBrowse link
G Itgb1 integrin subunit beta 1 increases expression
decreases expression
multiple interactions
EXP
ISO
Glucose results in increased expression of ITGB1 mRNA; Glucose results in increased expression of ITGB1 protein
Glucose results in decreased expression of ITGB1 mRNA
notoginsenoside R1 inhibits the reaction [Glucose results in decreased expression of ITGB1 mRNA]; notoginsenoside R1 inhibits the reaction [Glucose results in decreased expression of ITGB1 protein]
Glucose results in decreased expression of ITGB1 mRNA; Glucose results in decreased expression of ITGB1 protein
rosiglitazone inhibits the reaction [Glucose results in increased expression of ITGB1 mRNA]; rosiglitazone inhibits the reaction [Glucose results in increased expression of ITGB1 protein]
CTD PMID:17441352 PMID:25503068 PMID:31655124 NCBI chr19:61,677,512...61,725,537
Ensembl chr19:61,677,542...61,725,535
JBrowse link
G Itgb3 integrin subunit beta 3 multiple interactions
decreases expression
ISO Glucose inhibits the reaction [Aspirin inhibits the reaction [Arachidonic Acid results in increased expression of ITGB3 protein]]
Glucose results in decreased expression of ITGB3 mRNA
CTD PMID:18413191 PMID:31655124 NCBI chr10:92,667,869...92,783,413
Ensembl chr10:92,667,869...92,783,410
JBrowse link
G Jak2 Janus kinase 2 multiple interactions
increases phosphorylation
ISO
EXP
(3,4-dihydroxyphenylamino)-2-imidazoline inhibits the reaction [Glucose promotes the reaction [AGT protein results in increased phosphorylation of JAK2 protein]]; 1,2-Dihydroxybenzene-3,5-Disulfonic Acid Disodium Salt inhibits the reaction [Glucose promotes the reaction [AGT protein results in increased phosphorylation of JAK2 protein]]; acetovanillone inhibits the reaction [Glucose promotes the reaction [AGT protein results in increased phosphorylation of JAK2 protein]]; Glucose promotes the reaction [AGT protein results in increased phosphorylation of JAK2 protein]; Rotenone inhibits the reaction [Glucose promotes the reaction [AGT protein results in increased phosphorylation of JAK2 protein]]; Valsartan inhibits the reaction [Glucose promotes the reaction [AGT protein results in increased phosphorylation of JAK2 protein]]
Glucose results in increased phosphorylation of JAK2 protein
alpha-cyano-(3,4-dihydroxy)-N-benzylcinnamide inhibits the reaction [Glucose results in increased phosphorylation of JAK2 protein]
CTD PMID:15677497 PMID:20060012 NCBI chr 1:247,398,667...247,457,521
Ensembl chr 1:247,398,598...247,458,509
JBrowse link
G Jun Jun proto-oncogene, AP-1 transcription factor subunit multiple interactions
affects localization
increases phosphorylation
increases expression
ISO
EXP
2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Glucose results in increased phosphorylation of JUN protein]; [Glucose co-treated with Lipopolysaccharides] results in increased expression of JUN protein; Aspirin inhibits the reaction [Glucose results in increased expression of JUN protein]; Clofibrate inhibits the reaction [Glucose results in increased expression of JUN protein]; Fenofibrate inhibits the reaction [Glucose results in increased expression of JUN protein]; GLO1 inhibits the reaction [Glucose promotes the reaction [JUN protein binds to HMGB1 promoter]]; GLO1 inhibits the reaction [Glucose promotes the reaction [JUN protein binds to S100A12 promoter]]; GLO1 inhibits the reaction [Glucose promotes the reaction [JUN protein binds to S100A8 promoter]]; Glucose promotes the reaction [JUN protein binds to HMGB1 promoter]; Glucose promotes the reaction [JUN protein binds to MMP9 promoter]; Glucose promotes the reaction [JUN protein binds to S100A12 promoter]; Glucose promotes the reaction [JUN protein binds to S100A8 promoter]; JUN promotes the reaction [Glucose results in increased expression of HMGB1 mRNA]; JUN promotes the reaction [Glucose results in increased expression of S100A12 mRNA]; JUN promotes the reaction [Glucose results in increased expression of S100A8 mRNA]; N-(oxo-5,6-dihydrophenanthridin-2-yl)-N,N-dimethylacetamide hydrochloride inhibits the reaction [Glucose promotes the reaction [JUN protein binds to MMP9 promoter]]; PARP1 protein affects the reaction [Glucose promotes the reaction [JUN protein binds to MMP9 promoter]]; SB 203580 inhibits the reaction [Glucose results in increased phosphorylation of JUN protein]
Glucose inhibits the reaction [IL1B protein results in increased phosphorylation of JUN protein]
Dactinomycin inhibits the reaction [Glucose results in increased expression of JUN mRNA]; diphenyliodonium inhibits the reaction [Glucose results in increased phosphorylation of JUN protein]; Quercetin inhibits the reaction [Glucose affects the localization of JUN protein]; Superoxides affects the reaction [Glucose results in increased phosphorylation of JUN protein]
CTD PMID:11123204 PMID:11557636 PMID:16572112 PMID:16600694 PMID:17178593 PMID:18180316 PMID:19132243 PMID:19833897 PMID:19861503 PMID:20542118 PMID:28478229 PMID:30098273 NCBI chr 5:114,011,184...114,014,277
Ensembl chr 5:114,011,189...114,014,277
JBrowse link
G Junb JunB proto-oncogene, AP-1 transcription factor subunit increases expression ISO Glucose results in increased expression of JUNB mRNA CTD PMID:17178593 NCBI chr19:26,092,972...26,094,756
Ensembl chr19:26,092,974...26,094,756
JBrowse link
G Kat6b lysine acetyltransferase 6B multiple interactions ISO [Glucose co-treated with INS1 protein] affects the expression of KAT6B mRNA CTD PMID:22951486 NCBI chr15:2,811,933...2,966,833
Ensembl chr15:2,813,537...2,966,576
JBrowse link
G Kcnh2 potassium voltage-gated channel subfamily H member 2 multiple interactions
decreases expression
decreases activity
ISO
EXP
[Deoxyglucose co-treated with Glucose deficiency] results in decreased activity of KCNH2 protein; alpha-Tocopherol inhibits the reaction [Glucose results in decreased activity of KCNH2 protein]; Deoxyglucose inhibits the reaction [Glucose results in decreased activity of KCNH2 protein]; Deoxyglucose promotes the reaction [Glucose deficiency results in decreased activity of KCNH2 protein]; manganese(III)-tetrakis(4-benzoic acid)porphyrin inhibits the reaction [Glucose results in decreased activity of KCNH2 protein]; Pyruvic Acid inhibits the reaction [[Deoxyglucose co-treated with Glucose deficiency] results in decreased activity of KCNH2 protein]; Sodium Cyanide inhibits the reaction [Glucose results in decreased activity of KCNH2 protein]
Glucose results in decreased expression of KCNH2 protein
Glucose deficiency results in decreased activity of KCNH2 protein; Glucose results in decreased activity of KCNH2 protein
CTD PMID:12531891 PMID:31729781 NCBI chr 4:7,355,066...7,387,282
Ensembl chr 4:7,355,574...7,387,253
JBrowse link
G Kcnip2 potassium voltage-gated channel interacting protein 2 decreases expression
increases methylation
ISO Glucose results in decreased expression of KCNIP2 mRNA
Glucose results in increased methylation of KCNIP2 promoter
CTD PMID:31525975 NCBI chr 1:265,549,610...265,573,393
Ensembl chr 1:265,549,593...265,573,409
Ensembl chr 1:265,549,593...265,573,409
JBrowse link
G Kcnj15 potassium inwardly-rectifying channel, subfamily J, member 15 increases expression ISO Glucose results in increased expression of KCNJ15 mRNA CTD PMID:31525975 NCBI chr11:35,545,185...35,588,517
Ensembl chr11:35,568,182...35,585,390
JBrowse link
G Kcnma1 potassium calcium-activated channel subfamily M alpha 1 multiple interactions ISO Glucose inhibits the reaction [[KCNMA1 protein binds to KCNMB1 protein] which results in decreased expression of BCL2 protein]; Glucose results in decreased activity of [KCNMA1 protein binds to KCNMB1 protein]; NS 1619 inhibits the reaction [Glucose inhibits the reaction [[KCNMA1 protein binds to KCNMB1 protein] which results in decreased expression of BCL2 protein]]; NS 1619 inhibits the reaction [Glucose results in decreased activity of [KCNMA1 protein binds to KCNMB1 protein]]; Tamoxifen inhibits the reaction [Glucose inhibits the reaction [[KCNMA1 protein binds to KCNMB1 protein] which results in decreased expression of BCL2 protein]]; Tamoxifen inhibits the reaction [Glucose results in decreased activity of [KCNMA1 protein binds to KCNMB1 protein]]; Tetraethylammonium promotes the reaction [Glucose results in decreased activity of [KCNMA1 protein binds to KCNMB1 protein]] CTD PMID:21413024 NCBI chr15:344,204...1,048,849
Ensembl chr15:344,360...1,047,956
JBrowse link
G Kcnmb1 potassium calcium-activated channel subfamily M regulatory beta subunit 1 multiple interactions ISO Glucose inhibits the reaction [[KCNMA1 protein binds to KCNMB1 protein] which results in decreased expression of BCL2 protein]; Glucose results in decreased activity of [KCNMA1 protein binds to KCNMB1 protein]; NS 1619 inhibits the reaction [Glucose inhibits the reaction [[KCNMA1 protein binds to KCNMB1 protein] which results in decreased expression of BCL2 protein]]; NS 1619 inhibits the reaction [Glucose results in decreased activity of [KCNMA1 protein binds to KCNMB1 protein]]; Tamoxifen inhibits the reaction [Glucose inhibits the reaction [[KCNMA1 protein binds to KCNMB1 protein] which results in decreased expression of BCL2 protein]]; Tamoxifen inhibits the reaction [Glucose results in decreased activity of [KCNMA1 protein binds to KCNMB1 protein]]; Tetraethylammonium promotes the reaction [Glucose results in decreased activity of [KCNMA1 protein binds to KCNMB1 protein]] CTD PMID:21413024 NCBI chr10:18,910,586...18,922,856
Ensembl chr10:18,906,010...18,919,639
JBrowse link
G Kcnn2 potassium calcium-activated channel subfamily N member 2 decreases expression
multiple interactions
ISO Glucose results in decreased expression of KCNN2 protein
FBXO32 protein affects the reaction [Glucose results in decreased expression of KCNN2 protein]
CTD PMID:30635400 NCBI chr18:39,331,894...39,479,574
Ensembl chr18:39,335,377...39,479,257
JBrowse link
G Kdm1a lysine demethylase 1A multiple interactions EXP KDM1A protein results in decreased susceptibility to [Oxygen deficiency co-treated with Glucose deficiency] CTD PMID:21124846 NCBI chr 5:154,909,003...154,965,171
Ensembl chr 5:154,909,003...154,965,171
JBrowse link
G Kdm1b lysine demethylase 1B multiple interactions ISO [Glucose co-treated with INS1 protein] affects the expression of KDM1B mRNA CTD PMID:22951486 NCBI chr17:17,987,972...18,028,808
Ensembl chr17:17,987,972...18,028,808
JBrowse link
G Kdm4b lysine demethylase 4B multiple interactions ISO [Glucose co-treated with INS1 protein] affects the expression of KDM4B mRNA CTD PMID:22951486 NCBI chr 9:10,656,035...10,734,127
Ensembl chr 9:10,653,216...10,734,073
JBrowse link
G Kdr kinase insert domain receptor multiple interactions
decreases expression
ISO [Oxygen deficiency co-treated with Glucose deficiency] results in increased expression of KDR protein
Glucose results in decreased expression of KDR mRNA
CTD PMID:19228841 PMID:31655124 NCBI chr14:34,727,677...34,787,127
Ensembl chr14:34,727,623...34,787,183
JBrowse link
G Keap1 Kelch-like ECH-associated protein 1 multiple interactions ISO [NFE2L2 protein co-treated with KEAP1 protein] affects the abundance of Glucose CTD PMID:23017736 NCBI chr 8:22,250,518...22,259,868
Ensembl chr 8:22,250,518...22,259,779
JBrowse link
G Kif1a kinesin family member 1A increases expression EXP Glucose results in increased expression of KIF1A protein CTD PMID:23776493 NCBI chr 9:100,171,851...100,253,626
Ensembl chr 9:100,171,772...100,253,609
JBrowse link
G Kif5b kinesin family member 5B decreases expression EXP Glucose results in decreased expression of KIF5B protein CTD PMID:23776493 NCBI chr17:54,181,416...54,219,048
Ensembl chr17:54,181,419...54,212,096
JBrowse link
G Kit KIT proto-oncogene receptor tyrosine kinase decreases expression ISO Glucose results in decreased expression of KIT mRNA CTD PMID:31655124 NCBI chr14:35,072,131...35,149,638
Ensembl chr14:35,072,108...35,149,610
JBrowse link
G Klf10 Kruppel-like factor 10 multiple interactions
increases expression
ISO Glucose promotes the reaction [AGT protein results in increased expression of KLF10 mRNA]; Valsartan inhibits the reaction [Glucose promotes the reaction [AGT protein results in increased expression of KLF10 mRNA]]
Glucose results in increased expression of KLF10 mRNA
CTD PMID:17178593 PMID:19225232 NCBI chr 7:77,156,010...77,162,096
Ensembl chr 7:77,156,006...77,162,148
JBrowse link
G Klf13 Kruppel-like factor 13 multiple interactions EXP [[Oxygen deficiency co-treated with Glucose deficiency] results in increased susceptibility to Carvedilol] which results in decreased expression of KLF13 mRNA CTD PMID:29122578 NCBI chr 1:124,772,596...124,803,363
Ensembl chr 1:124,772,596...124,803,363
JBrowse link
G Klf6 Kruppel-like factor 6 increases expression ISO Glucose results in increased expression of KLF6 mRNA CTD PMID:17178593 NCBI chr17:67,887,939...67,945,052
Ensembl chr17:67,887,939...67,945,037
JBrowse link
G Klf9 Kruppel-like factor 9 increases expression ISO Glucose results in increased expression of KLF9 mRNA CTD PMID:17178593 NCBI chr 1:240,908,483...240,933,198
Ensembl chr 1:240,908,483...240,933,198
JBrowse link
G Klkb1 kallikrein B1 increases expression ISO Glucose results in increased expression of KLKB1 mRNA CTD PMID:31525975 NCBI chr16:50,151,127...50,175,407
Ensembl chr16:50,152,008...50,175,458
JBrowse link
G Krt20 keratin 20 multiple interactions
decreases expression
ISO [Glucose co-treated with TGFB1 protein] results in decreased expression of KRT20 protein; MAPK14 protein promotes the reaction [[Glucose co-treated with TGFB1 protein] results in decreased expression of KRT20 protein]; MAPK14 protein promotes the reaction [Glucose results in decreased expression of KRT20 mRNA]; MAPK14 protein promotes the reaction [Glucose results in decreased expression of KRT20 protein]
Glucose results in decreased expression of KRT20 mRNA; Glucose results in decreased expression of KRT20 protein
CTD PMID:21829520 NCBI chr10:87,342,514...87,351,045
Ensembl chr10:87,342,619...87,351,045
JBrowse link
G Lamb1 laminin subunit beta 1 multiple interactions ISO TXNIP promotes the reaction [Glucose results in increased expression of LAMB1 mRNA] CTD PMID:17178593 NCBI chr 6:50,528,796...50,596,593
Ensembl chr 6:50,528,823...50,596,079
JBrowse link
G Lamb2 laminin subunit beta 2 multiple interactions ISO TXNIP promotes the reaction [Glucose results in increased expression of LAMB2 mRNA] CTD PMID:17178593 NCBI chr 8:117,268,335...117,280,517
Ensembl chr 8:117,268,337...117,280,517
JBrowse link
G Lamb3 laminin subunit beta 3 multiple interactions ISO TXNIP promotes the reaction [Glucose results in increased expression of LAMB3 mRNA] CTD PMID:17178593 NCBI chr13:112,031,614...112,073,187
Ensembl chr13:112,031,594...112,073,186
JBrowse link
G Lamc1 laminin subunit gamma 1 multiple interactions ISO TXNIP promotes the reaction [Glucose results in increased expression of LAMC1 mRNA] CTD PMID:17178593 NCBI chr13:70,656,727...70,783,515
Ensembl chr13:70,658,707...70,783,515
JBrowse link
G Lamp1 lysosomal-associated membrane protein 1 increases expression EXP Glucose results in increased expression of LAMP1 protein CTD PMID:22253932 NCBI chr16:81,689,576...81,714,341
Ensembl chr16:81,689,335...81,714,419
JBrowse link
G Lamp2 lysosomal-associated membrane protein 2 multiple interactions ISO [Oxygen deficiency co-treated with Glucose deficiency] results in increased expression of LAMP2 protein CTD PMID:21392095 NCBI chr  X:124,722,628...124,766,079
Ensembl chr  X:124,722,628...124,766,044
JBrowse link
G Lct lactase multiple interactions
increases hydrolysis
EXP [Aspirin results in decreased activity of LCT protein] which results in decreased transport of Glucose; [nimesulide results in decreased activity of LCT protein] which results in decreased transport of Glucose
LCT protein results in increased hydrolysis of Glucose
CTD PMID:14701853 PMID:16382204 NCBI chr13:44,998,414...45,040,593
Ensembl chr13:44,998,414...45,040,593
JBrowse link
G Ldha lactate dehydrogenase A multiple interactions
increases expression
EXP
ISO
LDHA protein results in decreased susceptibility to [Oxygen deficiency co-treated with Glucose deficiency]
Glucose affects the reaction [Fusaric Acid results in increased expression of LDHA mRNA]
Glucose results in increased expression of LDHA protein
CTD PMID:21124846 PMID:27566995 PMID:31654802 NCBI chr 1:102,900,288...102,909,713
Ensembl chr 1:102,900,286...102,909,707
JBrowse link
G Ldhb lactate dehydrogenase B affects metabolic processing ISO LDHB protein affects the metabolism of Glucose CTD PMID:23437403 NCBI chr 4:176,701,980...176,719,999
Ensembl chr 4:176,701,983...176,720,012
JBrowse link
G Ldhd lactate dehydrogenase D increases expression ISO Glucose results in increased expression of LDHD mRNA CTD PMID:31525975 NCBI chr19:43,826,989...43,848,937
Ensembl chr19:43,826,993...43,848,937
JBrowse link
G Ldlr low density lipoprotein receptor multiple interactions ISO [LDLR gene mutant form results in increased susceptibility to Pravastatin] inhibits the reaction [Glucose results in increased secretion of INS1 protein] CTD PMID:26875785 NCBI chr 8:22,750,425...22,773,305
Ensembl chr 8:22,750,336...22,774,903
JBrowse link
G Lef1 lymphoid enhancer binding factor 1 increases expression
multiple interactions
ISO Glucose results in increased expression of LEF1 mRNA
DKK1 protein inhibits the reaction [Glucose results in increased expression of LEF1 mRNA]
CTD PMID:29163160 NCBI chr 2:236,232,115...236,345,061
Ensembl chr 2:236,233,239...236,345,056
JBrowse link
G Lep leptin multiple interactions
increases secretion
increases expression
increases response to substance
ISO
EXP
Glucose promotes the reaction [LEP protein results in increased chemical synthesis of Reactive Oxygen Species]; LEP protein promotes the reaction [Glucose results in increased chemical synthesis of Reactive Oxygen Species]
[LEP gene mutant form results in increased susceptibility to [Methionine co-treated with Choline]] which results in decreased abundance of Glucose
Glucose results in increased secretion of LEP protein
Glucose results in increased expression of LEP mRNA; Glucose results in increased expression of LEP protein
Glucose results in increased susceptibility to LEP protein
1,2-bis(2-aminophenoxy)ethane N,N,N',N'-tetraacetic acid acetoxymethyl ester inhibits the reaction [[Glucose co-treated with INS1 protein] results in increased secretion of LEP protein]; [[Glucose co-treated with INS1 protein] results in increased abundance of Adenosine Triphosphate] which results in increased secretion of LEP protein; [Glucose co-treated with INS1 protein] results in increased secretion of LEP protein; argan oil inhibits the reaction [Glucose results in increased expression of LEP protein]; Calcium deficiency inhibits the reaction [[Glucose co-treated with INS1 protein] results in increased secretion of LEP protein]; Corn Oil inhibits the reaction [Glucose results in increased expression of LEP protein]; Diazoxide inhibits the reaction [[Glucose co-treated with INS1 protein] results in increased secretion of LEP protein]; INS1 protein promotes the reaction [Glucose results in increased expression of LEP mRNA]; INS1 protein promotes the reaction [Glucose results in increased secretion of LEP protein]; LEP promotes the reaction [Glucose results in increased secretion of INS1 protein]; naringin inhibits the reaction [Glucose results in increased expression of LEP protein]; nickel chloride inhibits the reaction [[Glucose co-treated with INS1 protein] results in increased secretion of LEP protein]
CTD PMID:9751766 PMID:10780946 PMID:11342529 PMID:18627777 PMID:24399619 PMID:27712037 PMID:29165388 NCBI chr 4:56,337,695...56,351,818
Ensembl chr 4:56,337,695...56,351,818
JBrowse link
G Lepr leptin receptor affects abundance
increases expression
multiple interactions
decreases response to substance
ISO
EXP
LEPR affects the abundance of Glucose; LEPR protein affects the abundance of Glucose
Glucose results in increased expression of LEPR protein
naringin inhibits the reaction [Glucose results in increased expression of LEPR protein]
Hesperidin affects the reaction [LEPR protein affects the abundance of Glucose]; naringin affects the reaction [LEPR protein affects the abundance of Glucose]
LEPR results in decreased susceptibility to Glucose
CTD PMID:16427799 PMID:20567778 PMID:24399619 NCBI chr 5:120,503,475...120,682,281
Ensembl chr 5:120,564,645...120,682,221
JBrowse link
G Lif LIF, interleukin 6 family cytokine multiple interactions
increases expression
ISO [Valsartan co-treated with Simvastatin] inhibits the reaction [Glucose promotes the reaction [AGT protein results in increased expression of LIF mRNA]]; Glucose promotes the reaction [AGT protein results in increased expression of LIF mRNA]; Valsartan inhibits the reaction [Glucose promotes the reaction [AGT protein results in increased expression of LIF mRNA]]
Glucose results in increased expression of LIF mRNA
CTD PMID:17178593 PMID:19225232 NCBI chr14:84,482,652...84,500,574
Ensembl chr14:84,482,674...84,500,642
JBrowse link
G Lipg lipase G, endothelial type decreases expression ISO Glucose results in decreased expression of LIPG mRNA CTD PMID:17178593 NCBI chr18:70,903,528...70,924,434
Ensembl chr18:70,901,710...70,924,708
JBrowse link
G Lipn lipase, family member N increases expression ISO Glucose results in increased expression of LIPN mRNA CTD PMID:31525975 NCBI chr 1:252,375,941...252,394,226
Ensembl chr 1:252,375,933...252,396,460
JBrowse link
G LOC100365958 Rdh2 protein-like decreases expression ISO Glucose results in decreased expression of RDH1 mRNA CTD PMID:25627686 NCBI chr 7:71,065,077...71,074,128
Ensembl chr 7:70,980,422...71,072,689
JBrowse link
G Lonp1 lon peptidase 1, mitochondrial multiple interactions
decreases expression
EXP LONP1 protein affects the reaction [SRT1720 inhibits the reaction [Glucose results in decreased expression of and results in decreased activity of ACO2 protein]]; LONP1 protein affects the reaction [SRT1720 inhibits the reaction [Glucose results in decreased expression of LONP1 protein]]; SRT1720 inhibits the reaction [Glucose results in decreased expression of LONP1 protein] CTD PMID:31639451 NCBI chr 9:10,428,853...10,441,180
Ensembl chr 9:10,428,853...10,441,177
JBrowse link
G Lpl lipoprotein lipase decreases activity
multiple interactions
ISO Glucose analog results in decreased activity of LPL protein
LPL protein promotes the reaction [Fatty Acids results in increased uptake of Glucose]
CTD PMID:9414485 PMID:20628023 NCBI chr16:22,537,687...22,561,487
Ensembl chr16:22,537,056...22,561,496
JBrowse link
G Mafa MAF bZIP transcription factor A multiple interactions
affects expression
increases expression
ISO
EXP
3,4-dihydro-5-methyl-1(2H)-isoquinolinone inhibits the reaction [Glucose inhibits the reaction [MAFA protein binds to INS promoter]]; 3-aminobenzamide inhibits the reaction [Glucose inhibits the reaction [MAFA protein binds to INS promoter]]; Niacinamide inhibits the reaction [Glucose inhibits the reaction [MAFA protein binds to INS promoter]]
Glucose affects the expression of MAFA mRNA
3,4-dihydro-5-methyl-1(2H)-isoquinolinone inhibits the reaction [Glucose results in decreased expression of MAFA mRNA]; 3,4-dihydro-5-methyl-1(2H)-isoquinolinone inhibits the reaction [Glucose results in decreased expression of MAFA protein]; 3-aminobenzamide inhibits the reaction [Glucose results in decreased expression of MAFA mRNA]; 3-aminobenzamide inhibits the reaction [Glucose results in decreased expression of MAFA protein]; lipopolysaccharide, Escherichia coli O111 B4 inhibits the reaction [Glucose results in increased expression of MAFA mRNA]
IL1B protein inhibits the reaction [Glucose results in increased expression of MAFA mRNA]; lipopolysaccharide, Escherichia coli O111 B4 inhibits the reaction [Glucose results in increased expression of MAFA mRNA]; Palmitic Acid inhibits the reaction [Glucose results in increased expression of MAFA mRNA]; TLR4 affects the reaction [lipopolysaccharide, Escherichia coli O111 B4 inhibits the reaction [Glucose results in increased expression of MAFA mRNA]]
CTD PMID:16505238 PMID:22558381 PMID:24349266 NCBI chr 7:116,779,368...116,781,815
Ensembl chr 7:116,780,681...116,781,766
JBrowse link
G Maff MAF bZIP transcription factor F increases expression ISO Glucose results in increased expression of MAFF mRNA CTD PMID:17178593 NCBI chr 7:120,580,743...120,592,095
Ensembl chr 7:120,580,743...120,592,095
JBrowse link
G Magt1 magnesium transporter 1 decreases expression ISO Glucose results in decreased expression of MAGT1 mRNA CTD PMID:17178593 NCBI chr  X:77,023,423...77,061,603
Ensembl chr  X:77,020,402...77,061,667
JBrowse link
G Mamdc2 MAM domain containing 2 decreases expression ISO Glucose results in decreased expression of MAMDC2 mRNA CTD PMID:31525975 NCBI chr 1:241,071,110...241,223,798
Ensembl chr 1:241,072,072...241,155,537
JBrowse link
G Map1lc3b microtubule-associated protein 1 light chain 3 beta multiple interactions
decreases expression
EXP 3-methyladenine inhibits the reaction [N-(1,3-benzodioxol-5-ylmethyl)-2,6-dichlorobenzamide inhibits the reaction [Glucose results in decreased expression of MAP1LC3B protein]]; N-(1,3-benzodioxol-5-ylmethyl)-2,6-dichlorobenzamide inhibits the reaction [Glucose results in decreased expression of MAP1LC3B protein]; Sirolimus promotes the reaction [N-(1,3-benzodioxol-5-ylmethyl)-2,6-dichlorobenzamide inhibits the reaction [Glucose results in decreased expression of MAP1LC3B protein]]; ULK1 protein affects the reaction [Glucose results in decreased expression of MAP1LC3B protein]; ULK1 protein affects the reaction [N-(1,3-benzodioxol-5-ylmethyl)-2,6-dichlorobenzamide inhibits the reaction [Glucose results in decreased expression of MAP1LC3B protein]] CTD PMID:29128638 NCBI chr19:53,635,449...53,643,970
Ensembl chr19:53,629,779...53,646,058
JBrowse link
G Map3k1 mitogen-activated protein kinase kinase kinase 1 increases expression
multiple interactions
ISO Glucose results in increased expression of MAP3K1 mRNA
resveratrol inhibits the reaction [Glucose results in increased expression of MAP3K1 mRNA]
CTD PMID:24659233 NCBI chr 2:43,329,516...43,393,203
Ensembl chr 2:43,329,516...43,393,207
JBrowse link
G Map3k4 mitogen activated protein kinase kinase kinase 4 increases expression
multiple interactions
ISO Glucose results in increased expression of MAP3K4 mRNA
resveratrol inhibits the reaction [Glucose results in increased expression of MAP3K4 mRNA]
CTD PMID:24659233 NCBI chr 1:48,625,714...48,711,642
Ensembl chr 1:48,625,743...48,711,642
JBrowse link
G Map3k5 mitogen-activated protein kinase kinase kinase 5 multiple interactions
increases expression
ISO Glucose deficiency promotes the reaction [DAXX protein binds to MAP3K5 protein]; Glucose results in increased phosphorylation of and results in increased activity of MAP3K5 protein
[[[[Glucose results in decreased expression of MIR17 mRNA] which results in increased expression of TXNIP mRNA] which results in increased expression of TXNIP protein] promotes the reaction [TXNIP protein binds to TXN1 protein]] which results in increased activity of MAP3K5 protein; [Glucose promotes the reaction [TXNIP protein binds to TXN1 protein]] which results in increased activity of MAP3K5 protein; Glucose results in increased phosphorylation of and results in increased activity of MAP3K5 protein
Glucose results in increased expression of MAP3K5 protein
CTD PMID:14505347 PMID:16731828 PMID:26660634 NCBI chr 1:15,412,603...15,613,752
Ensembl chr 1:15,412,603...15,613,746
JBrowse link
G Mapk1 mitogen activated protein kinase 1 increases activity
increases phosphorylation
multiple interactions
affects phosphorylation
increases expression
decreases phosphorylation
ISO
EXP
Glucose deficiency results in increased activity of MAPK1 protein
Glucose results in increased phosphorylation of MAPK1 protein
4,4',4''-(4-propyl-((1)H)-pyrazole-1,3,5-triyl) tris-phenol inhibits the reaction [Glucose results in increased phosphorylation of MAPK1 protein]; CAT inhibits the reaction [Glucose deficiency results in increased activity of MAPK1 protein]; Catechin inhibits the reaction [Glucose results in increased phosphorylation of MAPK1 protein]; epigallocatechin gallate inhibits the reaction [Glucose results in increased phosphorylation of MAPK1 protein]; EUK-134 inhibits the reaction [Glucose results in increased phosphorylation of MAPK1 protein]; fulvestrant inhibits the reaction [4,4',4''-(4-propyl-((1)H)-pyrazole-1,3,5-triyl) tris-phenol inhibits the reaction [Glucose results in increased phosphorylation of MAPK1 protein]]; Glucose results in increased phosphorylation of and results in increased activity of MAPK1 protein; Heparin analog inhibits the reaction [Glucose results in increased phosphorylation of MAPK1 protein]; Luteolin inhibits the reaction [Glucose results in increased phosphorylation of MAPK1 protein]; Quercetin inhibits the reaction [Glucose results in increased phosphorylation of MAPK1 protein]; Rutin inhibits the reaction [Glucose results in increased phosphorylation of MAPK1 protein]; Tetradecanoylphorbol Acetate inhibits the reaction [Glucose deficiency results in increased activity of MAPK1 protein]
Glucose affects the phosphorylation of MAPK1 protein
Glucose results in increased expression of MAPK1 protein modified form
2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [[sphingosine 1-phosphate co-treated with Glucose] results in increased expression of MAPK1 protein modified form]; 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Glucose results in increased phosphorylation of MAPK1 protein]; [sphingosine 1-phosphate co-treated with Glucose] results in increased expression of MAPK1 protein modified form; cinnamic aldehyde inhibits the reaction [Glucose results in increased phosphorylation of MAPK1 protein]; diphenyleneiodonium inhibits the reaction [Glucose results in increased phosphorylation of MAPK1 protein]; diphenyliodonium inhibits the reaction [Glucose results in increased phosphorylation of MAPK1 protein]; farrerol inhibits the reaction [Glucose results in increased phosphorylation of MAPK1 protein]; Glucose results in increased phosphorylation of and results in increased activity of MAPK1 protein; Hydrogen Peroxide promotes the reaction [Glucose results in increased expression of MAPK1 protein modified form]; MAPK1 protein promotes the reaction [NRG1 protein results in increased transport of Glucose]; N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [Quercetin promotes the reaction [Glucose results in increased expression of MAPK1 protein modified form]]; PRKCB protein affects the reaction [Glucose results in increased phosphorylation of and results in increased activity of MAPK1 protein]; Quercetin promotes the reaction [Glucose results in increased expression of MAPK1 protein modified form]; Resveratrol inhibits the reaction [Glucose results in increased phosphorylation of MAPK1 protein]; ruboxistaurin inhibits the reaction [Glucose results in increased phosphorylation of and results in increased activity of MAPK1 protein]; Superoxides affects the reaction [Glucose results in increased phosphorylation of MAPK1 protein]; U 0126 inhibits the reaction [Glucose results in increased expression of MAPK1 protein modified form]; U 0126 inhibits the reaction [Quercetin promotes the reaction [Glucose results in increased expression of MAPK1 protein modified form]]
2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Glucose results in increased phosphorylation of and results in increased activity of MAPK1 protein]; [Oxygen deficiency co-treated with Glucose deficiency] results in increased phosphorylation of MAPK1 protein; Glucose inhibits the reaction [IL1B protein results in increased phosphorylation of MAPK1 protein]; Glucose promotes the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased phosphorylation of MAPK1 protein]; Glucose results in increased phosphorylation of and results in increased activity of MAPK1 protein; Resveratrol inhibits the reaction [[Oxygen deficiency co-treated with Glucose deficiency] results in increased phosphorylation of MAPK1 protein]; Silymarin promotes the reaction [Glucose promotes the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased phosphorylation of MAPK1 protein]]; SOD1 protein inhibits the reaction [[Oxygen deficiency co-treated with Glucose deficiency] results in increased phosphorylation of MAPK1 protein]
Glucose results in decreased phosphorylation of MAPK1 protein
CTD PMID:14711829 PMID:16572112 PMID:17309078 PMID:18057711 PMID:18310510 PMID:19020779 PMID:19228841 PMID:19303870 PMID:19557821 PMID:19587355 PMID:19861503 PMID:20060012 PMID:20200188 PMID:20860660 PMID:20962025 PMID:22162761 PMID:22406263 PMID:23690508 PMID:24682241 PMID:24971582 PMID:29753610 PMID:30098273 PMID:31838053 NCBI chr11:88,203,863...88,273,301
Ensembl chr11:88,211,599...88,273,254
JBrowse link
G Mapk14 mitogen activated protein kinase 14 multiple interactions
decreases phosphorylation
increases activity
ISO CAT inhibits the reaction [Glucose deficiency results in increased activity of MAPK14 protein]; MAPK14 protein promotes the reaction [[Glucose co-treated with TGFB1 protein] results in decreased expression of CDH1 protein]; MAPK14 protein promotes the reaction [[Glucose co-treated with TGFB1 protein] results in decreased expression of KRT20 protein]; MAPK14 protein promotes the reaction [[Glucose co-treated with TGFB1 protein] results in increased expression of ACTA2 protein]; MAPK14 protein promotes the reaction [[Glucose co-treated with TGFB1 protein] results in increased expression of VIM protein]; MAPK14 protein promotes the reaction [Glucose results in decreased expression of CDH1 protein]; MAPK14 protein promotes the reaction [Glucose results in decreased expression of KRT20 mRNA]; MAPK14 protein promotes the reaction [Glucose results in decreased expression of KRT20 protein]; MAPK14 protein promotes the reaction [Glucose results in increased expression of ACTA2 protein]; MAPK14 protein promotes the reaction [Glucose results in increased expression of SNAI1 mRNA]; MAPK14 protein promotes the reaction [Glucose results in increased expression of VIM mRNA]; MAPK14 protein promotes the reaction [Glucose results in increased secretion of FN1 protein]; Tetradecanoylphorbol Acetate inhibits the reaction [Glucose deficiency results in increased activity of MAPK14 protein]
[resveratrol co-treated with Glucose] results in decreased expression of MAPK14 mRNA; Glucose promotes the reaction [EIF2AK2 protein results in increased activity of MAPK14 protein]
Glucose results in decreased phosphorylation of MAPK14 protein
CTD PMID:17309078 PMID:18973755 PMID:20200188 PMID:21829520 PMID:24659233 NCBI chr20:5,933,290...5,995,137
Ensembl chr20:5,933,303...5,995,137
JBrowse link
G Mapk3 mitogen activated protein kinase 3 increases activity
increases phosphorylation
multiple interactions
increases expression
affects phosphorylation
decreases phosphorylation
ISO
EXP
Glucose deficiency results in increased activity of MAPK3 protein
Glucose results in increased phosphorylation of MAPK3 protein
4,4',4''-(4-propyl-((1)H)-pyrazole-1,3,5-triyl) tris-phenol inhibits the reaction [Glucose results in increased phosphorylation of MAPK3 protein]; CAT inhibits the reaction [Glucose deficiency results in increased activity of MAPK3 protein]; Catechin inhibits the reaction [Glucose results in increased phosphorylation of MAPK3 protein]; epigallocatechin gallate inhibits the reaction [Glucose results in increased phosphorylation of MAPK3 protein]; EUK-134 inhibits the reaction [Glucose results in increased phosphorylation of MAPK3 protein]; fulvestrant inhibits the reaction [4,4',4''-(4-propyl-((1)H)-pyrazole-1,3,5-triyl) tris-phenol inhibits the reaction [Glucose results in increased phosphorylation of MAPK3 protein]]; Glucose results in increased phosphorylation of and results in increased activity of MAPK3 protein; Heparin analog inhibits the reaction [Glucose results in increased phosphorylation of MAPK3 protein]; Luteolin inhibits the reaction [Glucose results in increased phosphorylation of MAPK3 protein]; Quercetin inhibits the reaction [Glucose results in increased phosphorylation of MAPK3 protein]; Rutin inhibits the reaction [Glucose results in increased phosphorylation of MAPK3 protein]; Tetradecanoylphorbol Acetate inhibits the reaction [Glucose deficiency results in increased activity of MAPK3 protein]
Glucose results in increased expression of MAPK3 protein modified form
Glucose affects the phosphorylation of MAPK3 protein
2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [[sphingosine 1-phosphate co-treated with Glucose] results in increased expression of MAPK3 protein modified form]; 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Glucose results in increased phosphorylation of MAPK3 protein]; [sphingosine 1-phosphate co-treated with Glucose] results in increased expression of MAPK3 protein modified form; cinnamic aldehyde inhibits the reaction [Glucose results in increased phosphorylation of MAPK3 protein]; diphenyleneiodonium inhibits the reaction [Glucose results in increased phosphorylation of MAPK3 protein]; diphenyliodonium inhibits the reaction [Glucose results in increased phosphorylation of MAPK3 protein]; farrerol inhibits the reaction [Glucose results in increased phosphorylation of MAPK3 protein]; Glucose results in increased phosphorylation of and results in increased activity of MAPK3 protein; Hydrogen Peroxide promotes the reaction [Glucose results in increased expression of MAPK3 protein modified form]; MAPK3 protein promotes the reaction [NRG1 protein results in increased transport of Glucose]; N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [Quercetin promotes the reaction [Glucose results in increased expression of MAPK3 protein modified form]]; PRKCB protein affects the reaction [Glucose results in increased phosphorylation of and results in increased activity of MAPK3 protein]; Quercetin promotes the reaction [Glucose results in increased expression of MAPK3 protein modified form]; Resveratrol inhibits the reaction [Glucose results in increased phosphorylation of MAPK3 protein]; ruboxistaurin inhibits the reaction [Glucose results in increased phosphorylation of and results in increased activity of MAPK3 protein]; Superoxides affects the reaction [Glucose results in increased phosphorylation of MAPK3 protein]; U 0126 inhibits the reaction [Glucose results in increased expression of MAPK3 protein modified form]; U 0126 inhibits the reaction [Quercetin promotes the reaction [Glucose results in increased expression of MAPK3 protein modified form]]
2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Glucose results in increased phosphorylation of and results in increased activity of MAPK3 protein]; [Oxygen deficiency co-treated with Glucose deficiency] results in increased phosphorylation of MAPK3 protein; Glucose inhibits the reaction [IL1B protein results in increased phosphorylation of MAPK3 protein]; Glucose promotes the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased phosphorylation of MAPK3 protein]; Glucose results in increased phosphorylation of and results in increased activity of MAPK3 protein; Resveratrol inhibits the reaction [[Oxygen deficiency co-treated with Glucose deficiency] results in increased phosphorylation of MAPK3 protein]; Silymarin promotes the reaction [Glucose promotes the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased phosphorylation of MAPK3 protein]]; SOD1 protein inhibits the reaction [[Oxygen deficiency co-treated with Glucose deficiency] results in increased phosphorylation of MAPK3 protein]
Glucose results in decreased phosphorylation of MAPK3 protein
CTD PMID:14711829 PMID:16572112 PMID:17309078 PMID:18057711 PMID:18310510 PMID:19020779 PMID:19228841 PMID:19303870 PMID:19557821 PMID:19587355 PMID:19861503 PMID:20060012 PMID:20200188 PMID:20860660 PMID:20962025 PMID:22162761 PMID:22406263 PMID:23690508 PMID:24682241 PMID:24971582 PMID:29753610 PMID:30098273 PMID:31838053 NCBI chr 1:198,192,773...198,198,975
Ensembl chr 1:198,192,773...198,198,975
JBrowse link
G Mapk8 mitogen-activated protein kinase 8 multiple interactions
increases phosphorylation
ISO
EXP
Glucose deficiency results in increased activity of and results in increased phosphorylation of MAPK8 protein
Glucose results in increased phosphorylation of MAPK8 protein
CTD PMID:14505347 PMID:19861503 NCBI chr16:9,620,854...9,709,342
Ensembl chr16:9,625,177...9,709,347
JBrowse link
G Mapk9 mitogen-activated protein kinase 9 increases phosphorylation EXP Glucose results in increased phosphorylation of MAPK9 protein CTD PMID:19861503 NCBI chr10:35,333,859...35,374,364
Ensembl chr10:35,333,859...35,374,355
JBrowse link
G Mdh1 malate dehydrogenase 1 increases expression EXP
ISO
Glucose results in increased expression of MDH1 mRNA
Glucose deficiency results in increased expression of MDH1 mRNA
CTD PMID:24349266 PMID:26811028 NCBI chr14:106,378,349...106,393,642
Ensembl chr14:106,378,942...106,393,670
JBrowse link
G Mdk midkine increases expression ISO Glucose results in increased expression of MDK protein CTD PMID:17607302 NCBI chr 3:80,841,003...80,843,895
Ensembl chr 3:80,841,005...80,842,916
JBrowse link
G Mesp2 mesoderm posterior bHLH transcription factor 2 decreases expression ISO Glucose results in decreased expression of MESP2 mRNA CTD PMID:31525975 NCBI chr 1:141,550,633...141,553,239
Ensembl chr 1:141,550,633...141,553,230
JBrowse link
G Mfap3 microfibril associated protein 3 multiple interactions EXP MFAP3 protein results in decreased susceptibility to [Oxygen deficiency co-treated with Glucose deficiency] CTD PMID:21124846 NCBI chr10:42,933,077...42,945,591
Ensembl chr10:42,933,077...42,945,564
JBrowse link
G Mfn1 mitofusin 1 decreases expression EXP Glucose results in decreased expression of MFN1 protein CTD PMID:27684054 NCBI chr 2:118,929,738...118,971,689
Ensembl chr 2:118,929,738...118,973,698
JBrowse link
G Mfn2 mitofusin 2 multiple interactions
decreases expression
increases expression
EXP cinnamic acid inhibits the reaction [Glucose results in decreased expression of MFN2 protein]; Metformin inhibits the reaction [Glucose results in decreased expression of MFN2 protein]; Oxygen deficiency inhibits the reaction [Glucose results in increased expression of MFN2 protein]; Sevoflurane inhibits the reaction [Oxygen deficiency inhibits the reaction [Glucose results in increased expression of MFN2 protein]] CTD PMID:27684054 PMID:30144576 NCBI chr 5:164,684,244...164,715,414
Ensembl chr 5:164,684,509...164,714,145
JBrowse link
G Mgam maltase-glucoamylase multiple interactions ISO [MGAM protein results in increased metabolism of maltodextrin] which results in increased abundance of Glucose; [MGAM protein results in increased metabolism of Maltose] which results in increased abundance of Glucose CTD PMID:17585022 NCBI chr 4:69,018,592...69,114,027
Ensembl chr 4:68,849,033...68,996,961
JBrowse link
G Mir133a1 microRNA 133a-1 increases expression
multiple interactions
ISO Glucose results in increased expression of MIR133A1 mRNA
MIR133A1 affects the reaction [Glucose results in decreased chemical synthesis of INS protein]
CTD PMID:20520763 NCBI chr18:2,052,478...2,052,564 JBrowse link
G Mir135a microRNA 135a multiple interactions EXP [Oxygen deficiency co-treated with Glucose deficiency] results in decreased expression of MIR135A mRNA; GSK3B protein inhibits the reaction [MIR135A mRNA inhibits the reaction [[Oxygen deficiency co-treated with Glucose deficiency] results in decreased expression of HMOX1 mRNA]]; GSK3B protein inhibits the reaction [MIR135A mRNA inhibits the reaction [[Oxygen deficiency co-treated with Glucose deficiency] results in decreased expression of NFE2L2 protein]]; GSK3B protein inhibits the reaction [MIR135A mRNA inhibits the reaction [[Oxygen deficiency co-treated with Glucose deficiency] results in decreased expression of NQO1 mRNA]]; GSK3B protein inhibits the reaction [MIR135A mRNA inhibits the reaction [[Oxygen deficiency co-treated with Glucose deficiency] results in increased activity of CASP3 protein]]; MIR135A mRNA inhibits the reaction [[Oxygen deficiency co-treated with Glucose deficiency] results in decreased expression of HMOX1 mRNA]; MIR135A mRNA inhibits the reaction [[Oxygen deficiency co-treated with Glucose deficiency] results in decreased expression of NFE2L2 protein]; MIR135A mRNA inhibits the reaction [[Oxygen deficiency co-treated with Glucose deficiency] results in decreased expression of NQO1 mRNA]; MIR135A mRNA inhibits the reaction [[Oxygen deficiency co-treated with Glucose deficiency] results in increased activity of CASP3 protein]; MIR135A mRNA inhibits the reaction [[Oxygen deficiency co-treated with Glucose deficiency] results in increased expression of GSK3B mRNA]; MIR135A mRNA inhibits the reaction [[Oxygen deficiency co-treated with Glucose deficiency] results in increased expression of GSK3B protein] CTD PMID:29719095 NCBI chr 7:32,894,877...32,894,976
Ensembl chr 7:32,894,877...32,894,976
JBrowse link
G Mir141 microRNA 141 increases expression ISO Glucose results in increased expression of MIR141 mRNA CTD PMID:26548909 NCBI chr 4:157,236,346...157,236,439
Ensembl chr 4:157,236,346...157,236,439
JBrowse link
G Mir144 microRNA 144 multiple interactions ISO [MIR144 mRNA results in decreased expression of SMARCA4 protein] affects the susceptibility to [Oxygen deficiency co-treated with Glucose deficiency]; [Oxygen deficiency co-treated with Glucose deficiency] results in decreased expression of MIR144 mRNA; MIR144 mRNA inhibits the reaction [[Oxygen deficiency co-treated with Glucose deficiency] results in increased expression of HMOX1 mRNA]; MIR144 mRNA inhibits the reaction [[Oxygen deficiency co-treated with Glucose deficiency] results in increased expression of NQO1 mRNA]; MIR144 mRNA inhibits the reaction [[Oxygen deficiency co-treated with Glucose deficiency] results in increased expression of SMARCA4 mRNA]; MIR144 mRNA inhibits the reaction [[Oxygen deficiency co-treated with Glucose deficiency] results in increased expression of SMARCA4 protein]; MIR144 mRNA promotes the reaction [[Oxygen deficiency co-treated with Glucose deficiency] results in increased activity of CASP3 protein] CTD PMID:29457851 NCBI chr10:65,291,365...65,291,447
Ensembl chr10:65,291,365...65,291,447
JBrowse link
G Mir145 microRNA 145 increases expression ISO Glucose results in increased expression of MIR145 mRNA CTD PMID:24223694 NCBI chr18:56,969,907...56,969,994
Ensembl chr18:56,969,907...56,969,994
JBrowse link
G Mir146a microRNA 146a increases expression
decreases expression
multiple interactions
ISO Glucose results in increased expression of MIR146A mRNA
Glucose results in decreased expression of MIR146 mRNA
Polyphenols inhibits the reaction [Glucose results in increased expression of MIR146A mRNA]
CTD PMID:20520763 PMID:21682256 NCBI chr10:28,962,476...28,962,570
Ensembl chr10:28,962,476...28,962,570
JBrowse link
G Mir148a microRNA 148a decreases expression ISO Glucose results in decreased expression of MIR148A mRNA CTD PMID:21682256 NCBI chr 4:81,013,269...81,013,365
Ensembl chr 4:81,013,269...81,013,365
JBrowse link
G Mir17 microRNA 17 decreases expression
multiple interactions
ISO Glucose results in decreased expression of MIR17 mRNA
[[[[Glucose results in decreased expression of MIR17 mRNA] which results in increased expression of TXNIP mRNA] which results in increased expression of TXNIP protein] promotes the reaction [TXNIP protein binds to TXN1 protein]] which results in increased activity of MAP3K5 protein; [Glucose results in decreased expression of MIR17 mRNA] which results in increased expression of TXNIP mRNA; [Glucose results in decreased expression of MIR17 mRNA] which results in increased stability of TXNIP protein
CTD PMID:26660634 NCBI chr15:100,179,879...100,179,962
Ensembl chr15:100,179,879...100,179,962
JBrowse link
G Mir184 microRNA 184 increases expression EXP Glucose results in increased expression of MIR184 mRNA CTD PMID:31729781 NCBI chr 8:97,175,657...97,175,733
Ensembl chr 8:97,175,657...97,175,733
JBrowse link
G Mir195 microRNA 195 increases expression EXP Glucose results in increased expression of MIR195 mRNA CTD PMID:31729781 NCBI chr10:56,845,301...56,845,387
Ensembl chr10:56,845,301...56,845,387
JBrowse link
G Mir200a microRNA 200a decreases expression ISO Glucose results in decreased expression of MIR200A mRNA CTD PMID:23776576 NCBI chr 5:173,489,366...173,489,454 JBrowse link
G Mir200b microRNA 200b decreases expression ISO Glucose results in decreased expression of MIR200B mRNA CTD PMID:23776576 NCBI chr 5:173,490,144...173,490,238
Ensembl chr 5:173,490,144...173,490,238
JBrowse link
G Mir210 microRNA 210 multiple interactions
increases expression
ISO
EXP
MIR210 mRNA inhibits the reaction [[Oxygen deficiency co-treated with Glucose deficiency] results in decreased expression of BCL2 mRNA]; MIR210 mRNA results in decreased susceptibility to [Oxygen deficiency co-treated with Glucose deficiency]
Glucose results in increased expression of MIR210 mRNA
CTD PMID:23108914 PMID:31729781 NCBI chr 1:214,208,355...214,208,464 JBrowse link
G Mir217 microRNA 217 multiple interactions
decreases expression
increases expression
EXP
ISO
MIR217 mRNA affects the reaction [Glucose results in decreased expression of SIRT1 mRNA]; MIR217 mRNA affects the reaction [Glucose results in decreased expression of SIRT1 protein]; MIR217 mRNA affects the reaction [Glucose results in increased expression of CCN2 protein]; MIR217 mRNA affects the reaction [Glucose results in increased expression of EDN1 protein]; MIR217 mRNA affects the reaction [Glucose results in increased expression of FN1 protein]; MIR217 mRNA affects the reaction [Glucose results in increased expression of HIF1A mRNA]; MIR217 mRNA affects the reaction [Glucose results in increased expression of HIF1A protein]; MIR217 mRNA affects the reaction [Glucose results in increased expression of TGFB1 protein]; MIR217 mRNA affects the reaction [Glucose results in increased expression of VEGFA protein]
MIR217 mRNA inhibits the reaction [Glucose results in increased secretion of IL1B protein]; MIR217 mRNA inhibits the reaction [Glucose results in increased secretion of IL6 protein]; MIR217 mRNA inhibits the reaction [Glucose results in increased secretion of TNF protein]
Glucose results in decreased expression of MIR217 mRNA
Glucose results in increased expression of MIR217 mRNA
CTD PMID:26891083 PMID:33283391 NCBI chr14:113,119,529...113,119,633
Ensembl chr14:113,119,529...113,119,633
JBrowse link
G Mir29a microRNA 29a multiple interactions EXP MIR29A mRNA inhibits the reaction [Glucose results in increased expression of CNR1 mRNA]; MIR29A mRNA inhibits the reaction [Glucose results in increased expression of CNR1 protein] CTD PMID:30642005 NCBI chr 4:58,343,931...58,344,018 JBrowse link
G Mir32 microRNA 32 decreases expression EXP Glucose results in decreased expression of MIR32 mRNA CTD PMID:31729781 NCBI chr 5:73,934,255...73,934,324
Ensembl chr 5:73,934,255...73,934,324
JBrowse link
G Mir322 microRNA 322 decreases expression
multiple interactions
ISO Glucose results in decreased expression of MIR322
MIR322 affects the reaction [Glucose results in increased cleavage of CASP3 protein]; tempol inhibits the reaction [Glucose results in decreased expression of MIR322]
CTD PMID:25516495 NCBI chr  X:158,148,161...158,148,255
Ensembl chr  X:158,148,161...158,148,255
JBrowse link
G Mir331 microRNA 331 increases expression EXP Glucose results in increased expression of MIR331 mRNA CTD PMID:31729781 NCBI chr 7:34,881,095...34,881,190
Ensembl chr 7:34,881,095...34,881,190
JBrowse link
G Mir3588 microRNA 3588 decreases expression EXP Glucose results in decreased expression of MIR3588 mRNA CTD PMID:31729781 NCBI chr11:16,097,337...16,097,442
Ensembl chr11:16,097,337...16,097,442
JBrowse link
G Mir484 microRNA 484 increases expression EXP Glucose results in increased expression of MIR484 mRNA CTD PMID:31729781 NCBI chr10:27,845...27,921
Ensembl chr10:27,845...27,921
JBrowse link
G Mir503 microRNA 503 increases expression EXP Glucose results in increased expression of MIR503 mRNA CTD PMID:31729781 NCBI chr  X:158,148,476...158,148,546
Ensembl chr  X:158,148,476...158,148,546
JBrowse link
G Mir6216 microRNA 6216 increases expression EXP Glucose results in increased expression of MIR6216 mRNA CTD PMID:31729781 NCBI chr 3:46,361,908...46,361,985
Ensembl chr 3:46,361,908...46,361,985
JBrowse link
G Mki67 marker of proliferation Ki-67 multiple interactions ISO [cobaltous chloride co-treated with Glucose] results in increased expression of MKI67 mRNA; [cobaltous chloride co-treated with Glucose] results in increased expression of MKI67 protein; scutellarin inhibits the reaction [[cobaltous chloride co-treated with Glucose] results in increased expression of MKI67 mRNA]; scutellarin inhibits the reaction [[cobaltous chloride co-treated with Glucose] results in increased expression of MKI67 protein] CTD PMID:25192544 NCBI chr 1:207,993,895...208,020,454
Ensembl chr 1:207,993,895...208,020,454
JBrowse link
G Mlx MAX dimerization protein MLX multiple interactions ISO Glucose promotes the reaction [MLX protein binds to TUG1 promoter] CTD PMID:32467232 NCBI chr10:88,997,011...89,002,154
Ensembl chr10:88,997,399...89,002,152
JBrowse link
G Mlxip MLX interacting protein multiple interactions ISO Glucose promotes the reaction [MLXIP protein binds to TUG1 promoter] CTD PMID:32467232 NCBI chr12:38,567,438...38,638,952
Ensembl chr12:38,567,247...38,638,536
JBrowse link
G Mlxipl MLX interacting protein-like increases expression
multiple interactions
EXP
ISO
Glucose results in increased expression of MLXIPL protein
Glucose promotes the reaction [MLXIPL protein binds to TUG1 promoter]
CTD PMID:16644726 PMID:16790840 PMID:32467232 NCBI chr12:24,590,645...24,619,639 JBrowse link
G Mme membrane metallo-endopeptidase decreases expression ISO Glucose results in decreased expression of MME mRNA CTD PMID:17178593 NCBI chr 2:153,799,203...153,880,910
Ensembl chr 2:153,803,349...153,880,738
JBrowse link
G Mmp1 matrix metallopeptidase 1 multiple interactions
decreases expression
ISO CD14 protein affects the reaction [Glucose promotes the reaction [Lipopolysaccharides results in increased secretion of MMP1 protein]]
Glucose results in decreased expression of MMP1 mRNA
CTD PMID:18180316 PMID:31655124 NCBI chr 8:5,703,206...5,723,593
Ensembl chr 8:5,703,206...5,723,591
JBrowse link
G Mmp14 matrix metallopeptidase 14 multiple interactions
decreases expression
ISO isoangustone A inhibits the reaction [Glucose results in decreased expression of MMP14 protein] CTD PMID:21367880 NCBI chr15:33,074,441...33,083,666
Ensembl chr15:33,074,441...33,083,655
JBrowse link
G Mmp2 matrix metallopeptidase 2 multiple interactions
decreases expression
increases activity
increases expression
ISO
EXP
resveratrol inhibits the reaction [Glucose results in increased activity of MMP2 protein]
Glucose results in decreased expression of MMP2 mRNA; Glucose results in decreased expression of MMP2 protein
Glucose promotes the reaction [Air Pollutants results in increased activity of MMP2 protein]; Glucose promotes the reaction [Air Pollutants results in increased expression of MMP2 mRNA]; Glucose promotes the reaction [Particulate Matter results in increased activity of MMP2 protein]; Glucose promotes the reaction [Particulate Matter results in increased expression of MMP2 mRNA]; SB 203580 inhibits the reaction [Glucose promotes the reaction [Air Pollutants results in increased activity of MMP2 protein]]; SB 203580 inhibits the reaction [Glucose promotes the reaction [Particulate Matter results in increased activity of MMP2 protein]]
farrerol inhibits the reaction [Glucose results in decreased expression of MMP2 mRNA]; farrerol inhibits the reaction [Glucose results in decreased expression of MMP2 protein]; Rosiglitazone inhibits the reaction [Glucose results in increased expression of MMP2 mRNA]; Rosiglitazone inhibits the reaction [Glucose results in increased expression of MMP2 protein]
Glucose results in increased expression of MMP2 mRNA; Glucose results in increased expression of MMP2 protein
CTD PMID:18665442 PMID:24659233 PMID:26179980 PMID:31838053 NCBI chr19:15,542,771...15,570,589
Ensembl chr19:15,542,765...15,570,611
JBrowse link
G Mmp9 matrix metallopeptidase 9 multiple interactions
decreases expression
increases expression
ISO
EXP
[Oxygen deficiency co-treated with Glucose deficiency] results in increased expression of MMP9 mRNA; [Oxygen deficiency co-treated with Glucose deficiency] results in increased expression of MMP9 protein; [Resveratrol co-treated with Glucose] results in decreased activity of MMP9 protein; Resveratrol inhibits the reaction [[Oxygen deficiency co-treated with Glucose deficiency] results in increased expression of MMP9 mRNA]; Resveratrol inhibits the reaction [[Oxygen deficiency co-treated with Glucose deficiency] results in increased expression of MMP9 protein]; U 0126 inhibits the reaction [[Oxygen deficiency co-treated with Glucose deficiency] results in increased expression of MMP9 mRNA]; U 0126 inhibits the reaction [[Oxygen deficiency co-treated with Glucose deficiency] results in increased expression of MMP9 protein]
Glucose results in decreased expression of MMP9 protein
Glucose results in increased expression of MMP9 mRNA
[Glucose co-treated with Resveratrol] results in decreased expression of MMP9 mRNA; Glucose promotes the reaction [Air Pollutants results in increased activity of MMP9 protein]; Glucose promotes the reaction [Air Pollutants results in increased expression of MMP9 mRNA]; Glucose promotes the reaction [JUN protein binds to MMP9 promoter]; Glucose promotes the reaction [PARP1 protein binds to MMP9 promoter]; Glucose promotes the reaction [Particulate Matter results in increased activity of MMP9 protein]; Glucose promotes the reaction [Particulate Matter results in increased expression of MMP9 mRNA]; Glucose promotes the reaction [RELA protein binds to MMP9 promoter]; N-(oxo-5,6-dihydrophenanthridin-2-yl)-N,N-dimethylacetamide hydrochloride inhibits the reaction [Glucose promotes the reaction [JUN protein binds to MMP9 promoter]]; N-(oxo-5,6-dihydrophenanthridin-2-yl)-N,N-dimethylacetamide hydrochloride inhibits the reaction [Glucose promotes the reaction [RELA protein binds to MMP9 promoter]]; N-(oxo-5,6-dihydrophenanthridin-2-yl)-N,N-dimethylacetamide hydrochloride inhibits the reaction [Glucose results in increased expression of MMP9 mRNA]; PARP1 protein affects the reaction [Glucose promotes the reaction [JUN protein binds to MMP9 promoter]]; PARP1 protein affects the reaction [Glucose promotes the reaction [RELA protein binds to MMP9 promoter]]; PARP1 protein affects the reaction [Glucose results in increased expression of MMP9 mRNA]; SB 203580 inhibits the reaction [Glucose promotes the reaction [Air Pollutants results in increased activity of MMP9 protein]]; SB 203580 inhibits the reaction [Glucose promotes the reaction [Particulate Matter results in increased activity of MMP9 protein]]; SIRT1 protein inhibits the reaction [Glucose promotes the reaction [PARP1 protein binds to MMP9 promoter]]
[Linoleic Acid co-treated with Glucose] affects the reaction [Azoxymethane affects the expression of MMP9 protein]; farrerol inhibits the reaction [Glucose results in decreased expression of MMP9 mRNA]; farrerol inhibits the reaction [Glucose results in decreased expression of MMP9 protein]; Glucose affects the reaction [Azoxymethane affects the expression of MMP9 protein]
CTD PMID:22467055 PMID:24064760 PMID:24659233 PMID:24682241 PMID:26179980 PMID:28478229 PMID:31655124 PMID:31838053 NCBI chr 3:161,413,410...161,421,473
Ensembl chr 3:161,413,298...161,421,520
JBrowse link
G Morc2 MORC family CW-type zinc finger 2 decreases expression ISO Glucose results in decreased expression of MORC2A mRNA CTD PMID:32467232 NCBI chr14:83,889,138...83,930,263
Ensembl chr14:83,889,089...83,930,522
JBrowse link
G Morf4l2 mortality factor 4 like 2 multiple interactions EXP MORF4L2 protein results in decreased susceptibility to [Oxygen deficiency co-treated with Glucose deficiency] CTD PMID:21124846 NCBI chr  X:107,394,468...107,405,564
Ensembl chr  X:107,394,486...107,405,564
JBrowse link
G Morn4 MORN repeat containing 4 multiple interactions EXP MORN4 protein results in decreased susceptibility to [Oxygen deficiency co-treated with Glucose deficiency] CTD PMID:21124846 NCBI chr 1:261,323,079...261,333,383
Ensembl chr 1:261,323,083...261,333,383
JBrowse link
G Mpo myeloperoxidase multiple interactions EXP [Oxygen deficiency co-treated with Glucose deficiency] results in increased activity of MPO protein; Quercetin inhibits the reaction [[Oxygen deficiency co-treated with Glucose deficiency] results in increased activity of MPO protein] CTD PMID:23758074 NCBI chr10:75,087,892...75,098,260
Ensembl chr10:75,087,892...75,098,260
JBrowse link
G Mras muscle RAS oncogene homolog multiple interactions
increases activity
EXP manumycin inhibits the reaction [Glucose results in increased activity of MRAS protein]; Simvastatin inhibits the reaction [Glucose results in increased activity of MRAS protein] CTD PMID:18569938 NCBI chr 8:107,629,028...107,656,851
Ensembl chr 8:107,629,028...107,681,512
JBrowse link
G Mt-atp6 mitochondrially encoded ATP synthase membrane subunit 6 affects response to substance EXP ATP6 protein affects the susceptibility to Glucose CTD PMID:18273840 NCBI chr MT:7,919...8,599
Ensembl chr MT:7,919...8,599
JBrowse link
G Mt-co1 mitochondrially encoded cytochrome c oxidase I multiple interactions EXP [Glucose deficiency co-treated with Galactose co-treated with Pyruvic Acid] results in increased expression of COX1 protein CTD PMID:25997894 NCBI chr MT:5,323...6,867
Ensembl chr MT:5,323...6,867
JBrowse link
G Mt-co2 mitochondrially encoded cytochrome c oxidase II increases expression ISO Glucose deficiency results in increased expression of COX2 mRNA CTD PMID:26811028 NCBI chr MT:7,006...7,689
Ensembl chr MT:7,006...7,689
JBrowse link
G Mt-cyb mitochondrially encoded cytochrome b multiple interactions
decreases expression
ISO N-(oxo-5,6-dihydrophenanthridin-2-yl)-N,N-dimethylacetamide hydrochloride inhibits the reaction [Glucose results in decreased expression of CYTB mRNA]; PARP1 protein affects the reaction [Glucose results in decreased expression of CYTB mRNA] CTD PMID:28478229 NCBI chr MT:14,136...15,278
Ensembl chr MT:14,136...15,278
JBrowse link
G Mt1 metallothionein 1 increases expression
multiple interactions
affects expression
EXP Glucose results in increased expression of MT1A mRNA
manganese(III)-tetrakis(4-benzoic acid)porphyrin affects the reaction [Glucose affects the expression of MT1A mRNA]; N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine inhibits the reaction [Glucose results in increased expression of MT1A mRNA]; zinc chloride promotes the reaction [Glucose results in increased expression of MT1A mRNA]
CTD PMID:22643931 PMID:23056475 NCBI chr19:11,301,991...11,303,007
Ensembl chr17:78,793,336...78,793,724
JBrowse link
G Mt2A metallothionein 2A multiple interactions
increases expression
EXP N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine inhibits the reaction [Glucose results in increased expression of MT2A mRNA]; zinc chloride promotes the reaction [Glucose results in increased expression of MT2A mRNA] CTD PMID:23056475 NCBI chr19:11,307,966...11,308,740
Ensembl chr19:11,307,967...11,308,740
JBrowse link
G Mtm1 myotubularin 1 decreases expression ISO Glucose results in decreased expression of MTM1 mRNA CTD PMID:17178593 NCBI chr 6:18,821,821...18,840,449
Ensembl chr 6:18,821,815...18,839,409
JBrowse link
G Mtor mechanistic target of rapamycin kinase increases activity
increases phosphorylation
multiple interactions
decreases uptake
increases expression
ISO
EXP
Glucose results in increased activity of MTOR protein
Glucose results in increased phosphorylation of MTOR protein
Resveratrol inhibits the reaction [Glucose results in increased phosphorylation of MTOR protein]
FOXP1 protein inhibits the reaction [Glucose results in increased phosphorylation of MTOR protein]
MTOR gene mutant form results in decreased uptake of Glucose
Glucose results in increased expression of MTOR protein; Glucose results in increased expression of MTOR protein modified form
HU 308 inhibits the reaction [Glucose results in increased phosphorylation of MTOR protein]; Resveratrol inhibits the reaction [Glucose results in increased activity of MTOR protein]
CTD PMID:19765649 PMID:22561310 PMID:28713934 PMID:29384525 PMID:30459625 PMID:31494106 NCBI chr 5:165,263,813...165,373,967
Ensembl chr 5:165,263,800...165,373,967
JBrowse link
G Mtx1 Metaxin 1 increases expression ISO Glucose results in increased expression of MTX1 mRNA CTD PMID:17178593 NCBI chr 2:188,522,605...188,528,747
Ensembl chr 2:188,521,785...188,528,195
JBrowse link
G Mxd1 max dimerization protein 1 multiple interactions ISO Glucose promotes the reaction [MXD1 protein binds to TUG1 promoter] CTD PMID:32467232 NCBI chr 4:118,451,752...118,472,150
Ensembl chr 4:118,449,882...118,472,179
JBrowse link
G Myc MYC proto-oncogene, bHLH transcription factor multiple interactions
affects expression
ISO
EXP
MYC protein affects the reaction [Tetrachlorodibenzodioxin results in decreased uptake of Glucose]
manganese(III)-tetrakis(4-benzoic acid)porphyrin affects the reaction [Glucose affects the expression of MYC mRNA]
Glucose affects the reaction [Dexamethasone results in increased expression of MYC mRNA]; Glucose affects the reaction [Tetradecanoylphorbol Acetate results in increased expression of MYC mRNA]
CTD PMID:2558650 PMID:11990355 PMID:22643931 NCBI chr 7:102,586,313...102,591,240
Ensembl chr 7:102,586,313...102,591,240
JBrowse link
G Myd88 MYD88, innate immune signal transduction adaptor increases expression
multiple interactions
EXP Glucose results in increased expression of MYD88 protein
artesunate inhibits the reaction [Glucose results in increased expression of MYD88 protein]
CTD PMID:30031708 NCBI chr 8:128,022,512...128,027,462
Ensembl chr 8:128,022,473...128,026,841
JBrowse link
G Myh2 myosin heavy chain 2 multiple interactions ISO MYH2 protein affects the reaction [SLC2A4 protein results in increased uptake of Glucose] CTD PMID:18773891 NCBI chr10:53,711,895...53,738,164
Ensembl chr10:53,713,938...53,848,347
JBrowse link
G Mylk myosin light chain kinase multiple interactions
increases uptake
ISO ML 7 inhibits the reaction [MYLK protein results in increased uptake of Glucose]; ML 9 inhibits the reaction [MYLK protein results in increased uptake of Glucose] CTD PMID:18773891 NCBI chr11:69,013,060...69,260,039
Ensembl chr11:69,013,050...69,223,158
JBrowse link
G Myo7b myosin VIIb decreases expression ISO Glucose results in decreased expression of MYO7B mRNA CTD PMID:31525975 NCBI chr18:24,742,329...24,823,889
Ensembl chr18:24,742,329...24,823,858
JBrowse link
G Nampt nicotinamide phosphoribosyltransferase decreases expression
multiple interactions
increases secretion
increases expression
ISO Glucose results in decreased expression of NAMPT mRNA
Diazoxide inhibits the reaction [Glucose results in increased secretion of NAMPT protein]; Nifedipine inhibits the reaction [Glucose results in increased secretion of NAMPT protein]
Glucose results in increased expression of NAMPT mRNA
CTD PMID:20068143 PMID:23536823 NCBI chr 6:52,122,085...52,156,473
Ensembl chr 6:52,122,085...52,156,472
JBrowse link
G Napa NSF attachment protein alpha decreases expression ISO Glucose deficiency results in decreased expression of NAPA protein CTD PMID:22314686 NCBI chr 1:77,994,227...78,012,846
Ensembl chr 1:77,994,203...78,012,845
JBrowse link
G Nbea neurobeachin decreases expression ISO Glucose results in decreased expression of NBEA mRNA CTD PMID:17178593 NCBI chr 2:145,011,648...145,513,439 JBrowse link
G Ncf1 neutrophil cytosolic factor 1 multiple interactions
increases phosphorylation
increases expression
affects localization
ISO
EXP
acetovanillone inhibits the reaction [Glucose results in increased expression of and results in increased activity of NCF1 protein]; bisindolylmaleimide I inhibits the reaction [Glucose affects the localization of NCF1 protein]; Glucose results in increased expression of and results in increased activity of NCF1 protein; manganese(III)-tetrakis(4-benzoic acid)porphyrin inhibits the reaction [Glucose results in increased expression of NCF1 protein]; PRKAA1 protein affects the reaction [rosiglitazone inhibits the reaction [Glucose affects the localization of NCF1 protein]]; rosiglitazone inhibits the reaction [Glucose affects the localization of NCF1 protein]
Glucose results in increased phosphorylation of NCF1 protein
Glucose results in increased expression of NCF1 mRNA; Glucose results in increased expression of NCF1 protein
[[[Glucose results in increased expression of CYBA protein] co-treated with [Glucose results in increased expression of NCF1 protein]] results in increased chemical synthesis of Reactive Oxygen Species] which results in increased expression of FN1 protein; [[Glucose results in increased expression of CYBA protein] co-treated with [Glucose results in increased expression of NCF1 protein]] results in increased chemical synthesis of Reactive Oxygen Species; bisindolylmaleimide I inhibits the reaction [Glucose results in increased expression of and results in increased phosphorylation of NCF1 protein]; dorsomorphin inhibits the reaction [Resveratrol inhibits the reaction [Glucose results in increased expression of NCF1 protein]]; Glucose results in increased expression of and results in increased phosphorylation of NCF1 protein; NCF1 protein promotes the reaction [Glucose results in increased chemical synthesis of Reactive Oxygen Species]; NCF1 protein promotes the reaction [Glucose results in increased expression of FN1 protein]; pyrazolanthrone inhibits the reaction [Glucose results in increased expression of NCF1 protein]; Resveratrol inhibits the reaction [[[[Glucose results in increased expression of CYBA protein] co-treated with [Glucose results in increased expression of NCF1 protein]] results in increased chemical synthesis of Reactive Oxygen Species] which results in increased expression of FN1 protein]; Resveratrol inhibits the reaction [Glucose results in increased expression of NCF1 mRNA]; Resveratrol inhibits the reaction [Glucose results in increased expression of NCF1 protein]; Resveratrol inhibits the reaction [Glucose results in increased phosphorylation of NCF1 protein]
CTD PMID:12821678 PMID:17320767 PMID:17916771 PMID:18088078 PMID:19878672 PMID:22245600 PMID:24971582 PMID:26054749 NCBI chr12:25,497,104...25,506,300
Ensembl chr12:25,497,104...25,506,300
JBrowse link
G Ncf2 neutrophil cytosolic factor 2 multiple interactions
increases expression
EXP dorsomorphin inhibits the reaction [Resveratrol inhibits the reaction [Glucose results in increased expression of NCF2 protein]]; Resveratrol inhibits the reaction [Glucose results in increased expression of NCF2 protein] CTD PMID:26054749 NCBI chr13:70,226,441...70,259,019
Ensembl chr13:70,226,647...70,257,576
JBrowse link
G Nckap5 NCK-associated protein 5 increases expression ISO Glucose results in increased expression of NCKAP5 mRNA CTD PMID:31525975 NCBI chr13:42,265,875...43,049,232
Ensembl chr13:42,265,806...42,885,440
JBrowse link
G Ndel1 nudE neurodevelopment protein 1-like 1 increases expression ISO Glucose results in increased expression of NDEL1 mRNA CTD PMID:17178593 NCBI chr10:55,398,919...55,456,654
Ensembl chr10:55,411,901...55,444,861
JBrowse link
G Ndrg2 NDRG family member 2 multiple interactions EXP
ISO
[Oxygen deficiency co-treated with Glucose deficiency] affects the localization of NDRG2 protein; [Oxygen deficiency co-treated with Glucose deficiency] results in increased expression of NDRG2 mRNA; [Oxygen deficiency co-treated with Glucose deficiency] results in increased expression of NDRG2 protein; NDRG2 protein affects the susceptibility to [Oxygen deficiency co-treated with Glucose deficiency]; TP53 protein affects the reaction [[Oxygen deficiency co-treated with Glucose deficiency] results in increased expression of NDRG2]
NDRG2 protein promotes the reaction [[Oxygen deficiency co-treated with Glucose deficiency] results in increased expression of BAX protein]
CTD PMID:23451161 NCBI chr15:28,305,820...28,314,459
Ensembl chr15:28,305,821...28,314,459
JBrowse link
G Ndufb8 NADH:ubiquinone oxidoreductase subunit B8 multiple interactions EXP [Glucose deficiency co-treated with Galactose co-treated with Pyruvic Acid] results in increased expression of NDUFB8 protein CTD PMID:25997894 NCBI chr 1:264,298,671...264,303,712
Ensembl chr 1:264,298,669...264,303,762
JBrowse link
G Nedd4l NEDD4 like E3 ubiquitin protein ligase decreases phosphorylation EXP Glucose results in decreased phosphorylation of NEDD4L protein CTD PMID:31729781 NCBI chr18:60,392,376...60,719,720
Ensembl chr18:60,392,376...60,719,720
JBrowse link
G Nfe2l2 nuclear factor, erythroid 2-like 2 multiple interactions
affects localization
decreases expression
affects response to substance
increases localization
increases expression
ISO
EXP
2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [spiraeoside inhibits the reaction [Glucose results in decreased expression of NFE2L2 protein]]; 2-chloro-5-nitrobenzanilide inhibits the reaction [Rosiglitazone inhibits the reaction [Glucose results in decreased expression of NFE2L2 protein]]; [Oxygen co-treated with Glucose] inhibits the reaction [[Oxygen deficiency co-treated with Glucose deficiency] results in decreased expression of NFE2L2 protein]; [Oxygen deficiency co-treated with Glucose deficiency] results in decreased expression of NFE2L2 protein; NFE2L2 mutant form inhibits the reaction [Berberine inhibits the reaction [Glucose results in increased abundance of Reactive Oxygen Species]]; Particulate Matter inhibits the reaction [[Oxygen co-treated with Glucose] inhibits the reaction [[Oxygen deficiency co-treated with Glucose deficiency] results in decreased expression of NFE2L2 protein]]; Rosiglitazone inhibits the reaction [Glucose results in decreased expression of NFE2L2 protein]; spiraeoside inhibits the reaction [Glucose results in decreased expression of NFE2L2 protein]; Vehicle Emissions inhibits the reaction [[Oxygen co-treated with Glucose] inhibits the reaction [[Oxygen deficiency co-treated with Glucose deficiency] results in decreased expression of NFE2L2 protein]]
Glucose affects the localization of NFE2L2 protein
[Oxygen deficiency co-treated with Glucose deficiency] results in decreased expression of NFE2L2 protein; diallyl trisulfide promotes the reaction [Glucose results in increased expression of and affects the localization of NFE2L2 protein]; Glucose results in increased expression of and affects the localization of NFE2L2 protein; GSK3B protein inhibits the reaction [MIR135A mRNA inhibits the reaction [[Oxygen deficiency co-treated with Glucose deficiency] results in decreased expression of NFE2L2 protein]]; MIR135A mRNA inhibits the reaction [[Oxygen deficiency co-treated with Glucose deficiency] results in decreased expression of NFE2L2 protein]; NFE2L2 mutant form inhibits the reaction [diallyl trisulfide inhibits the reaction [Glucose results in increased cleavage of CASP3 protein]]; NFE2L2 protein affects the reaction [Exenatide inhibits the reaction [Hydrogen Peroxide inhibits the reaction [Glucose results in increased secretion of INS1 protein]]]; NFE2L2 protein affects the reaction [ginsenoside Rh4 inhibits the reaction [Alloxan inhibits the reaction [Glucose results in increased secretion of INS1 protein]]]; NFE2L2 protein mutant form affects the reaction [plumbagin inhibits the reaction [[Oxygen deficiency co-treated with Glucose deficiency] results in increased activity of CASP3 protein]]; NFE2L2 protein promotes the reaction [diallyl trisulfide inhibits the reaction [[Oxygen deficiency co-treated with Glucose deficiency] results in increased expression of CASP3 protein modified form]]; Quercetin inhibits the reaction [Glucose results in decreased expression of NFE2L2 mRNA]; Quercetin inhibits the reaction [Glucose results in decreased expression of NFE2L2 protein]; SRT1720 inhibits the reaction [Glucose results in decreased expression of NFE2L2 protein]
Glucose results in decreased expression of NFE2L2 mRNA; Glucose results in decreased expression of NFE2L2 protein
NFE2L2 protein affects the susceptibility to Glucose
2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one affects the reaction [SMARCA4A protein affects the reaction [Glucose affects the localization of NFE2L2 protein]]; [NFE2L2 protein binds to TXNIP promoter] inhibits the reaction [Glucose results in increased expression of TXNIP mRNA]; [NFE2L2 protein co-treated with KEAP1 protein] affects the abundance of Glucose; [NFE2L2 protein mutant form co-treated with Streptozocin] results in increased abundance of Glucose; NFE2L2 mutant form inhibits the reaction [Glucose deficiency promotes the reaction [Simvastatin results in increased expression of HMOX1 mRNA]]; NFE2L2 protein affects the reaction [SMARCA4A protein inhibits the reaction [Glucose results in increased expression of FN1 mRNA]]; NFE2L2 protein inhibits the reaction [Glucose results in increased expression of TXNIP mRNA]; SMARCA4A protein affects the reaction [Glucose affects the localization of NFE2L2 protein]
Glucose deficiency results in increased localization of NFE2L2 protein
Glucose deficiency results in increased expression of NFE2L2 mRNA; Glucose deficiency results in increased expression of NFE2L2 protein; Glucose results in increased expression of NFE2L2; Glucose results in increased expression of NFE2L2 protein
CTD PMID:17928392 PMID:20028456 PMID:20086057 PMID:20103708 PMID:21333731 PMID:21818840 PMID:22869588 PMID:23017736 PMID:23453443 PMID:23770986 PMID:23954465 PMID:25896937 PMID:27939242 PMID:28400208 PMID:29649567 PMID:29719095 PMID:31639451 PMID:32602595 PMID:33270355 PMID:33359794 NCBI chr 3:62,497,568...62,525,146
Ensembl chr 3:62,497,571...62,524,996
JBrowse link
G Nfkb1 nuclear factor kappa B subunit 1 increases expression
multiple interactions
ISO Glucose results in increased expression of NFKB1 mRNA; Glucose results in increased expression of NFKB1 protein
[Oxygen deficiency co-treated with Glucose deficiency] results in increased expression of NFKB1 protein; Glucose results in increased activity of and affects the localization of NFKB1 protein; INO 1001 inhibits the reaction [Glucose results in increased activity of and affects the localization of NFKB1 protein]; NFKB1 protein inhibits the reaction [SOD1 protein promotes the reaction [[Oxygen deficiency co-treated with Glucose deficiency] results in increased expression of PTGS2 protein]]; SOD1 protein inhibits the reaction [[Oxygen deficiency co-treated with Glucose deficiency] results in increased expression of and results in increased activity of NFKB1 protein]
[Glucose results in increased susceptibility to sodium arsenite] which results in increased expression of NFKB1 mRNA; Polyphenols inhibits the reaction [Glucose results in increased expression of NFKB1 mRNA]
CTD PMID:16395278 PMID:17065336 PMID:18180316 PMID:21682256 PMID:28264687 NCBI chr 2:240,773,520...240,890,053
Ensembl chr 2:240,773,456...240,866,689
JBrowse link
G Nfkbia NFKB inhibitor alpha multiple interactions
increases phosphorylation
increases expression
decreases expression
ISO
EXP
2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Glucose results in increased phosphorylation of NFKBIA protein]; Catechin inhibits the reaction [Glucose results in increased degradation of and results in decreased expression of NFKBIA protein]; epigallocatechin gallate inhibits the reaction [Glucose results in increased degradation of and results in decreased expression of NFKBIA protein]; Glucose results in increased degradation of and results in decreased expression of NFKBIA protein; Luteolin inhibits the reaction [Glucose results in increased degradation of and results in decreased expression of NFKBIA protein]; Quercetin inhibits the reaction [Glucose results in increased degradation of and results in decreased expression of NFKBIA protein]; Rutin inhibits the reaction [Glucose results in increased degradation of and results in decreased expression of NFKBIA protein]; SB 203580 inhibits the reaction [Glucose results in increased phosphorylation of NFKBIA protein]
3,3',4,5'-tetrahydroxystilbene inhibits the reaction [Glucose results in decreased expression of NFKBIA protein]; Glucose results in increased phosphorylation of and results in increased degradation of NFKBIA protein; prolinedithiocarbamate inhibits the reaction [Glucose results in decreased expression of NFKBIA protein]; pyrazolanthrone inhibits the reaction [Glucose results in increased phosphorylation of and results in increased degradation of NFKBIA protein]; Quercetin inhibits the reaction [Glucose results in increased expression of NFKBIA protein modified form]; Quercetin inhibits the reaction [Glucose results in increased expression of NFKBIA protein]; Resveratrol inhibits the reaction [Glucose results in increased phosphorylation of and results in increased degradation of NFKBIA protein]; Resveratrol inhibits the reaction [Glucose results in increased phosphorylation of NFKBIA protein]; Sulfasalazine inhibits the reaction [Glucose results in increased phosphorylation of and results in increased degradation of NFKBIA protein]; Y 27632 inhibits the reaction [Glucose results in decreased expression of NFKBIA protein]
Glucose results in increased expression of NFKBIA protein; Glucose results in increased expression of NFKBIA protein modified form
Glucose results in increased expression of NFKBIA mRNA
[Oxygen deficiency co-treated with Glucose deficiency] results in increased degradation of NFKBIA protein; [Oxygen deficiency co-treated with Glucose deficiency] results in increased phosphorylation of and results in increased degradation of NFKBIA protein; [Ribose co-treated with Glucose] results in increased phosphorylation of NFKBIA protein; acetovanillone inhibits the reaction [Glucose results in increased phosphorylation of NFKBIA protein]; INO 1001 inhibits the reaction [Glucose results in increased phosphorylation of NFKBIA protein]; N-(oxo-5,6-dihydrophenanthridin-2-yl)-N,N-dimethylacetamide hydrochloride inhibits the reaction [Glucose results in increased phosphorylation of NFKBIA protein]; Prodigiosin inhibits the reaction [[Oxygen deficiency co-treated with Glucose deficiency] results in increased degradation of NFKBIA protein]; prolinedithiocarbamate inhibits the reaction [[Oxygen deficiency co-treated with Glucose deficiency] results in increased degradation of NFKBIA protein]
CTD PMID:16395278 PMID:17065336 PMID:17178593 PMID:19132243 PMID:19557821 PMID:21925195 PMID:22245600 PMID:23376009 PMID:23770986 PMID:24971582 PMID:30101366 PMID:31323227 NCBI chr 6:76,267,227...76,270,457
Ensembl chr 6:76,267,228...76,270,457
JBrowse link
G Ngf nerve growth factor multiple interactions
decreases activity
decreases expression
ISO
EXP
Berberine inhibits the reaction [Glucose results in decreased expression of NGF protein]
Glucose results in decreased activity of NGF protein
CTD PMID:19501110 PMID:23954465 NCBI chr 2:204,886,158...204,939,523
Ensembl chr 2:204,886,202...204,940,453
JBrowse link
G Nkx6-1 NK6 homeobox 1 multiple interactions ISO NKX6-1 protein promotes the reaction [Glucose results in increased secretion of INS protein] CTD PMID:18347054 NCBI chr14:9,555,264...9,562,197
Ensembl chr14:9,555,264...9,562,189
JBrowse link
G Nlrp3 NLR family, pyrin domain containing 3 multiple interactions
increases response to substance
increases expression
ISO
EXP
Allopurinol inhibits the reaction [Glucose results in increased expression of NLRP3 protein]; Quercetin inhibits the reaction [Glucose results in increased expression of NLRP3 protein]
NLRP3 protein results in increased susceptibility to Glucose
NLRP3 protein promotes the reaction [Glucose results in decreased expression of TJP1 protein]; NLRP3 protein promotes the reaction [Glucose results in decreased expression of TJP2 protein]; NLRP3 protein promotes the reaction [Glucose results in increased secretion of HMGB1 protein]
Allopurinol inhibits the reaction [Glucose results in increased expression of NLRP3 protein]; artesunate inhibits the reaction [Glucose results in increased expression of NLRP3 protein]; ethyl 6-(N-(2-chloro-4-fluorophenyl)sulfamoyl)cyclohex-1-ene-1-carboxylate inhibits the reaction [Glucose results in increased expression of NLRP3 protein]; prolinedithiocarbamate inhibits the reaction [Glucose results in increased expression of NLRP3 protein]; Quercetin inhibits the reaction [Glucose results in increased expression of NLRP3 protein]; rhodioloside inhibits the reaction [Glucose results in increased expression of NLRP3 protein]
CTD PMID:23647015 PMID:27783111 PMID:29031534 PMID:30031708 NCBI chr10:45,884,324...45,918,290
Ensembl chr10:45,893,018...45,918,254
JBrowse link
G Nmu neuromedin U increases expression
decreases methylation
ISO Glucose results in increased expression of NMU mRNA
Glucose results in decreased methylation of NMU promoter
CTD PMID:31525975 NCBI chr14:34,353,683...34,381,968
Ensembl chr14:34,354,503...34,381,828
JBrowse link
G Nnt nicotinamide nucleotide transhydrogenase affects response to substance
decreases metabolic processing
ISO NNT protein affects the susceptibility to Glucose
NNT protein results in decreased metabolism of Glucose
CTD PMID:23504317 NCBI chr 2:52,189,523...52,283,095
Ensembl chr 2:52,189,529...52,282,548
JBrowse link
G Nol6 nucleolar protein 6 multiple interactions EXP NOL6 protein results in decreased susceptibility to [Oxygen deficiency co-treated with Glucose deficiency] CTD PMID:21124846 NCBI chr 5:57,444,448...57,473,803
Ensembl chr 5:57,445,344...57,455,018
JBrowse link
G Nono non-POU domain containing, octamer-binding affects metabolic processing ISO NONO gene mutant form affects the metabolism of Glucose CTD PMID:29358041 NCBI chr  X:71,324,365...71,342,225
Ensembl chr  X:71,324,365...71,342,225
JBrowse link
G Nos1 nitric oxide synthase 1 decreases expression
multiple interactions
ISO Glucose deficiency results in decreased expression of NOS1 protein
Nitroprusside inhibits the reaction [Glucose deficiency results in decreased expression of NOS1 protein]
CTD PMID:17855661 NCBI chr12:44,214,949...44,405,530
Ensembl chr12:44,213,943...44,520,341
JBrowse link
G Nos2 nitric oxide synthase 2 increases expression
multiple interactions
ISO
EXP
Glucose results in increased expression of NOS2 mRNA; Glucose results in increased expression of NOS2 protein
[Linoleic Acid co-treated with Glucose] affects the reaction [Azoxymethane affects the expression of NOS2 protein]; [Oxygen co-treated with Glucose] promotes the reaction [[Oxygen deficiency co-treated with Glucose deficiency] results in increased expression of NOS2 protein]; [Oxygen deficiency co-treated with Glucose deficiency] results in increased expression of NOS2 protein; PRKCB protein affects the reaction [Glucose results in increased expression of NOS2 protein]; Quercetin inhibits the reaction [Glucose results in increased expression of NOS2 mRNA]; Quercetin inhibits the reaction [Glucose results in increased expression of NOS2 protein]; ruboxistaurin inhibits the reaction [Glucose results in increased expression of NOS2 protein]
SOD1 protein inhibits the reaction [Glucose results in increased expression of NOS2 mRNA]; SOD1 protein inhibits the reaction [Glucose results in increased expression of NOS2 protein]
[Glucose co-treated with lipopolysaccharide, Escherichia coli O111 B4] results in increased expression of NOS2 protein; [Oxygen deficiency co-treated with Glucose deficiency] results in increased expression of NOS2 protein; Prodigiosin inhibits the reaction [[Oxygen deficiency co-treated with Glucose deficiency] results in increased expression of NOS2 protein]; prolinedithiocarbamate inhibits the reaction [[Oxygen deficiency co-treated with Glucose deficiency] results in increased expression of NOS2 protein]; Silymarin inhibits the reaction [[Glucose co-treated with lipopolysaccharide, Escherichia coli O111 B4] results in increased expression of NOS2 protein]
CTD PMID:19587355 PMID:21925195 PMID:22363694 PMID:22425406 PMID:22467055 PMID:23061969 PMID:23770986 PMID:29753610 PMID:30076216 NCBI chr10:66,188,290...66,221,621
Ensembl chr10:66,189,786...66,313,190
JBrowse link
G Nos3 nitric oxide synthase 3 decreases expression
increases expression
multiple interactions
increases O-linked glycosylation
decreases phosphorylation
ISO
EXP
Glucose deficiency results in decreased expression of NOS3 protein; Glucose results in decreased expression of NOS3 mRNA; Glucose results in decreased expression of NOS3 protein
Glucose results in increased expression of NOS3 mRNA; Glucose results in increased expression of NOS3 protein
Glucose results in decreased expression of and results in decreased phosphorylation of NOS3 protein; pimagedine inhibits the reaction [Glucose results in decreased expression of and results in decreased phosphorylation of NOS3 protein]
2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [Rosiglitazone inhibits the reaction [[Glucose results in decreased phosphorylation of NOS3 protein] which results in increased abundance of Nitric Oxide]]; 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [Rosiglitazone inhibits the reaction [Glucose results in decreased phosphorylation of NOS3 protein]]; [Glucose results in decreased phosphorylation of NOS3 protein] which results in increased abundance of Nitric Oxide; [salvianolic acid co-treated with Glucose] inhibits the reaction [6-chloro-2,3,4,9-tetrahydro-1H-carbazole-1-carboxamide results in decreased phosphorylation of NOS3 protein]; acetovanillone inhibits the reaction [Glucose results in decreased expression of NOS3 protein]; cobaltiprotoporphyrin inhibits the reaction [Glucose results in decreased expression of NOS3 protein]; Glucose inhibits the reaction [6-chloro-2,3,4,9-tetrahydro-1H-carbazole-1-carboxamide results in decreased phosphorylation of NOS3 protein]; Glucose results in increased expression of and results in increased activity of NOS3 protein; Nitroprusside inhibits the reaction [Glucose deficiency results in decreased expression of NOS3 protein]; Resveratrol inhibits the reaction [Glucose results in decreased expression of NOS3 mRNA]; Rosiglitazone inhibits the reaction [[Glucose results in decreased phosphorylation of NOS3 protein] which results in increased abundance of Nitric Oxide]; Rosiglitazone inhibits the reaction [Glucose results in decreased phosphorylation of NOS3 protein]; salvianolic acid inhibits the reaction [Glucose results in decreased phosphorylation of NOS3 protein]; SIRT1 protein affects the reaction [Resveratrol inhibits the reaction [Glucose results in decreased expression of NOS3 mRNA]]; TRPM7 affects the reaction [Glucose results in decreased expression of NOS3 protein]; U 0126 inhibits the reaction [TRPM7 affects the reaction [Glucose results in decreased expression of NOS3 protein]]; Wortmannin inhibits the reaction [Rosiglitazone inhibits the reaction [[Glucose results in decreased phosphorylation of NOS3 protein] which results in increased abundance of Nitric Oxide]]; Wortmannin inhibits the reaction [Rosiglitazone inhibits the reaction [Glucose results in decreased phosphorylation of NOS3 protein]]
Glucose results in increased O-linked glycosylation of NOS3 protein
CTD PMID:10502298 PMID:11696579 PMID:15490108 PMID:17075048 PMID:17090780 PMID:17855661 PMID:18483403 PMID:19767878 PMID:19878672 PMID:19924377 PMID:20960276 PMID:24223965 PMID:30431688 NCBI chr 4:7,321,908...7,342,404
Ensembl chr 4:7,320,668...7,342,410
JBrowse link
G Nox1 NADPH oxidase 1 multiple interactions
increases expression
ISO Glucose results in increased expression of and results in increased activity of NOX1 protein; resveratrol inhibits the reaction [Glucose results in increased expression of and results in increased activity of NOX1 protein]; resveratrol inhibits the reaction [Glucose results in increased expression of NOX1 mRNA] CTD PMID:23731528 NCBI chr  X:104,909,328...104,932,508
Ensembl chr  X:104,909,326...104,932,508
JBrowse link
G Nox4 NADPH oxidase 4 multiple interactions
increases expression
EXP
ISO
2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Glucose results in increased expression of NOX4 protein]; [Oxygen deficiency co-treated with Glucose deficiency] results in increased expression of NOX4 mRNA; Antigen-Antibody Complex inhibits the reaction [[Oxygen deficiency co-treated with Glucose deficiency] results in increased expression of NOX4 mRNA]; diphenyliodonium inhibits the reaction [Glucose results in increased expression of NOX4 protein]; farrerol inhibits the reaction [Glucose results in increased expression of NOX4 mRNA]; farrerol inhibits the reaction [Glucose results in increased expression of NOX4 protein]
Glucose results in increased expression of NOX4 mRNA; Glucose results in increased expression of NOX4 protein
FOXP1 protein inhibits the reaction [Glucose results in increased expression of NOX4 protein]
CTD