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ONTOLOGY REPORT - ANNOTATIONS


Term:3-methyl-3H-imidazo[4,5-f]quinolin-2-amine
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Accession:CHEBI:42725 term browser browse the term
Definition:An imidazoquinoline that is 3H-imidazo[4,5-f]quinoline substituted by a methyl group at position 3 and an amino group at position 2.
Synonyms:related_synonym: Formula=C11H10N4;   IQ;   InChI=1S/C11H10N4/c1-15-9-5-4-8-7(3-2-6-13-8)10(9)14-11(15)12/h2-6H,1H3,(H2,12,14);   InChIKey=ARZWATDYIYAUTA-UHFFFAOYSA-N;   SMILES=Cn1c(N)nc2c1ccc1ncccc21
 xref: CAS:76180-96-6 "ChemIDplus";   CAS:76180-96-6 "KEGG COMPOUND";   HMDB:HMDB0029706;   KEGG:C19180
 xref_mesh: MESH:C029216
 xref: PDBeChem:GIQ;   PMID:24135607 "Europe PMC";   Reaxys:5014055 "Reaxys"


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3-methyl-3H-imidazo[4,5-f]quinolin-2-amine term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Abcc2 ATP binding cassette subfamily C member 2 JBrowse link 1 263,554,426 263,612,556 RGD:6480464
G Ahr aryl hydrocarbon receptor JBrowse link 6 54,963,990 55,001,806 RGD:6480464
G Akr1b10 aldo-keto reductase family 1 member B10 JBrowse link 4 61,813,265 61,830,371 RGD:6480464
G Apc APC regulator of WNT signaling pathway JBrowse link 18 27,011,710 27,106,323 RGD:6480464
G Aprt adenine phosphoribosyl transferase JBrowse link 19 55,387,288 55,389,256 RGD:6480464
G Asf1a anti-silencing function 1A histone chaperone JBrowse link 20 34,894,419 34,909,265 RGD:6480464
G Bik BCL2-interacting killer JBrowse link 7 124,390,924 124,410,449 RGD:6480464
G Cdh1 cadherin 1 JBrowse link 19 38,768,467 38,838,395 RGD:6480464
G Cdkn1a cyclin-dependent kinase inhibitor 1A JBrowse link 20 6,348,422 6,358,864 RGD:6480464
G Ctnnb1 catenin beta 1 JBrowse link 8 129,601,511 129,628,378 RGD:6480464
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 JBrowse link 8 62,472,087 62,478,122 RGD:6480464
G Cyp1a2 cytochrome P450, family 1, subfamily a, polypeptide 2 JBrowse link 8 62,451,360 62,458,244 RGD:6480464
G Fbxo30 F-box protein 30 JBrowse link 1 5,366,119 5,389,774 RGD:6480464
G Gpat3 glycerol-3-phosphate acyltransferase 3 JBrowse link 14 10,343,287 10,396,565 RGD:6480464
G Gsk3b glycogen synthase kinase 3 beta JBrowse link 11 65,060,884 65,208,842 RGD:6480464
G H2afx H2A histone family, member X JBrowse link 8 48,665,652 48,666,981 RGD:6480464
G Hprt1 hypoxanthine phosphoribosyltransferase 1 JBrowse link X 158,196,640 158,228,815 RGD:6480464
G Hras HRas proto-oncogene, GTPase JBrowse link 1 214,178,404 214,181,841 RGD:6480464
G Jun Jun proto-oncogene, AP-1 transcription factor subunit JBrowse link 5 114,011,184 114,014,277 RGD:6480464
G Kras KRAS proto-oncogene, GTPase JBrowse link 4 179,482,562 179,515,483 RGD:6480464
G Lif LIF, interleukin 6 family cytokine JBrowse link 14 84,482,652 84,500,574 RGD:6480464
G Nat2 N-acetyltransferase 2 JBrowse link 16 23,960,709 23,991,570 RGD:6480464
G Oat ornithine aminotransferase JBrowse link 1 204,562,289 204,582,070 RGD:6480464
G Por cytochrome p450 oxidoreductase JBrowse link 12 23,998,411 24,017,063 RGD:6480464
G Ptgs1 prostaglandin-endoperoxide synthase 1 JBrowse link 3 15,560,685 15,582,339 RGD:6480464
G Ptgs2 prostaglandin-endoperoxide synthase 2 JBrowse link 13 67,351,230 67,356,920 RGD:6480464
G Rrm2b ribonucleotide reductase regulatory TP53 inducible subunit M2B JBrowse link 7 76,750,045 76,780,817 RGD:6480464
G Slc7a11 solute carrier family 7 member 11 JBrowse link 2 139,453,774 139,528,479 RGD:6480464
G Tgfbr1 transforming growth factor, beta receptor 1 JBrowse link 5 63,056,071 63,119,635 RGD:6480464
G Tgfbr2 transforming growth factor, beta receptor 2 JBrowse link 8 124,310,288 124,399,345 RGD:6480464
G Wnt1 Wnt family member 1 JBrowse link 7 140,464,999 140,469,046 RGD:6480464

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19617
    role 19560
      biological role 19553
        aetiopathogenetic role 18692
          carcinogenic agent 17760
            3-methyl-3H-imidazo[4,5-f]quinolin-2-amine 31
Path 2
Term Annotations click to browse term
  CHEBI ontology 19617
    subatomic particle 19613
      composite particle 19613
        hadron 19613
          baryon 19613
            nucleon 19613
              atomic nucleus 19613
                atom 19613
                  main group element atom 19491
                    p-block element atom 19491
                      carbon group element atom 19363
                        carbon atom 19355
                          organic molecular entity 19355
                            organic molecule 19272
                              organic cyclic compound 19062
                                organic heterocyclic compound 18129
                                  organic heteropolycyclic compound 17365
                                    organic heterotricyclic compound 13729
                                      imidazoquinoline 123
                                        3-methyl-3H-imidazo[4,5-f]quinolin-2-amine 31
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.