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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:propiophenone
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Accession:CHEBI:425902 term browser browse the term
Definition:An aromatic ketone in which the two substituents on the carbonyl C atom are phenyl and ethyl.
Synonyms:related_synonym: 1-Phenyl-1-propanone;   1-Phenyl-propan-1-one;   1-phenylpropan-1-one;   Ethyl phenyl ketone;   Formula=C9H10O;   InChI=1S/C9H10O/c1-2-9(10)8-6-4-3-5-7-8/h3-7H,2H2,1H3;   InChIKey=KRIOVPPHQSLHCZ-UHFFFAOYSA-N;   Propionphenone;   Propionylbenzene;   SMILES=CCC(=O)c1ccccc1
 xref: Beilstein:606215;   CAS:93-55-0;   HMDB:HMDB0032623;   PDBeChem:I1E;   PMID:24302226;   Patent:CN101759540;   Reaxys:606215;   Wikipedia:Propiophenone

show annotations for term's descendants           Sort by:
 
2-aminopropiophenone term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Slc6a3 solute carrier family 6 member 3 decreases expression ISO cathinone analog results in decreased expression of SLC6A3 mRNA CTD PMID:28173643 NCBI chr 1:32,323,011...32,363,983
Ensembl chr 1:32,321,580...32,363,983 		JBrowse link
mephedrone term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Casp3 caspase 3 increases activity ISO mephedrone results in increased activity of CASP3 protein CTD PMID:32382956 NCBI chr16:48,845,011...48,863,249
Ensembl chr16:48,845,012...48,863,204 		JBrowse link
G Cat catalase decreases expression
increases expression		 EXP
ISO		 mephedrone results in decreased expression of CAT protein
mephedrone results in increased expression of CAT protein		 CTD PMID:25817894 PMID:26747301 NCBI chr 3:93,379,872...93,412,058
Ensembl chr 3:93,379,874...93,412,058 		JBrowse link
G Drd2 dopamine receptor D2 decreases expression EXP mephedrone results in decreased expression of DRD2 protein CTD PMID:25817894 NCBI chr 8:53,678,777...53,743,643
Ensembl chr 8:53,678,777...53,743,642 		JBrowse link
G Gpx1 glutathione peroxidase 1 decreases expression
increases expression		 EXP
ISO		 mephedrone results in decreased expression of GPX1 protein
mephedrone results in increased expression of GPX1 protein		 CTD PMID:25817894 PMID:26747301 NCBI chr 8:117,117,430...117,118,528
Ensembl chr 8:117,117,430...117,118,522 		JBrowse link
G Nos1 nitric oxide synthase 1 affects expression EXP mephedrone affects the expression of NOS1 protein CTD PMID:25817894 NCBI chr12:44,214,949...44,405,530
Ensembl chr12:44,213,943...44,520,341 		JBrowse link
G Slc6a3 solute carrier family 6 member 3 decreases expression
multiple interactions		 EXP
ISO		 mephedrone results in decreased expression of SLC6A3 protein
Ethanol promotes the reaction [mephedrone results in decreased expression of SLC6A3 protein]		 CTD PMID:25817894 PMID:26747301 NCBI chr 1:32,323,011...32,363,983
Ensembl chr 1:32,321,580...32,363,983 		JBrowse link
G Slc6a4 solute carrier family 6 member 4 multiple interactions
decreases expression		 ISO
EXP		 Ethanol promotes the reaction [mephedrone results in decreased expression of SLC6A4 protein] CTD PMID:25817894 PMID:26747301 NCBI chr10:63,153,656...63,188,377
Ensembl chr10:63,153,651...63,176,463 		JBrowse link
G Sod1 superoxide dismutase 1 affects expression EXP mephedrone affects the expression of SOD1 protein CTD PMID:25817894 NCBI chr11:30,363,282...30,368,858
Ensembl chr11:30,363,280...30,368,862 		JBrowse link
G Th tyrosine hydroxylase multiple interactions
decreases expression		 ISO
EXP		 Ethanol promotes the reaction [mephedrone results in decreased expression of TH protein] CTD PMID:25817894 PMID:26747301 NCBI chr 1:216,073,034...216,080,287
Ensembl chr 1:216,073,031...216,080,287 		JBrowse link
G Tph2 tryptophan hydroxylase 2 multiple interactions
decreases expression		 ISO
EXP		 Ethanol promotes the reaction [mephedrone results in decreased expression of TPH2 protein] CTD PMID:25817894 PMID:26747301 NCBI chr 7:58,042,279...58,149,220
Ensembl chr 7:58,042,281...58,149,061 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19770
    role 19720
      application 19411
        fragrance 868
          propiophenone 10
            2,3-diacetoxypropioveratrone 0
            2-aminopropiophenone + 1
            2-hydroxy-1-phenyl-1-propanone 0
            4-methylpropiophenone 0
            diethylpropion + 0
            mephedrone 10
Path 2
Term Annotations click to browse term
  CHEBI ontology 19770
    subatomic particle 19768
      composite particle 19768
        hadron 19768
          baryon 19768
            nucleon 19768
              atomic nucleus 19768
                atom 19768
                  main group element atom 19662
                    p-block element atom 19662
                      carbon group element atom 19580
                        carbon atom 19571
                          organic molecular entity 19571
                            organic group 18602
                              organic divalent group 18593
                                organodiyl group 18593
                                  carbonyl group 18506
                                    carbonyl compound 18506
                                      ketone 16825
                                        aromatic ketone 12098
                                          propiophenone 10
                                            2,3-diacetoxypropioveratrone 0
                                            2-aminopropiophenone + 1
                                            2-hydroxy-1-phenyl-1-propanone 0
                                            4-methylpropiophenone 0
                                            diethylpropion + 0
                                            mephedrone 10
paths to the root