Send us a Message



Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   

CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:forskolin
go back to main search page
Accession:CHEBI:42471 term browser browse the term
Definition:A labdane diterpenoid isolated from the Indian Coleus plant.
Synonyms:exact_synonym: (3R,4aR,5S,6S,6aS,10S,10aR,10bS)-3-ethenyl-6,10,10b-trihydroxy-3,4a,7,7,10a-pentamethyl-1-oxododecahydro-1H-benzo[f]chromen-5-yl acetate
 related_synonym: 7beta-acetoxy-8,13-epoxy-1alpha,6beta,9alpha-trihydroxylabd-14-en-11-one;   Coleonol;   Coleonolk;   Formula=C22H34O7;   InChI=1S/C22H34O7/c1-8-19(5)11-14(25)22(27)20(6)13(24)9-10-18(3,4)16(20)15(26)17(28-12(2)23)21(22,7)29-19/h8,13,15-17,24,26-27H,1,9-11H2,2-7H3/t13-,15-,16-,17-,19-,20-,21+,22-/m0/s1;   InChIKey=OHCQJHSOBUTRHG-KGGHGJDLSA-N;   SMILES=[H][C@@]12[C@H](O)[C@H](OC(C)=O)[C@@]3(C)O[C@](C)(CC(=O)[C@]3(O)[C@@]1(C)[C@@H](O)CCC2(C)C)C=C;   colforsin;   colforsina;   colforsine;   colforsinum
 xref: Beilstein:4300863;   CAS:66428-89-5;   CAS:66575-29-9;   DrugBank:DB02587;   KEGG:C09076;   KEGG:D03584;   KNApSAcK:C00003416;   PDBeChem:FOK;   PMID:11816015;   PMID:12676767;   PMID:12836714;   PMID:14691682;   PMID:15135319;   PMID:15380183;   PMID:1547891;   PMID:15525467;   PMID:16644480;   PMID:17570033;   PMID:19831022;   PMID:7755573;   PMID:7875530;   PMID:7898427;   PMID:7929167;   PMID:8489512;   PMID:8985363;   PMID:9478958;   PMID:9828101;   Patent:DE2557784;   Patent:US4088659;   Patent:US4476140;   Reaxys:4300863;   Wikipedia:Forskolin



show annotations for term's descendants           Sort by:
 
forskolin term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Slc6a4 solute carrier family 6 member 4 increases activity ISO forskolin increases activity of SLC6A4 protein in placental choriocarcinoma cells RGD PMID:8408014 RGD:36947876 NCBI chr10:61,824,208...61,858,924
Ensembl chr10:61,826,123...61,858,384
JBrowse link
1,9-dideoxyforskolin term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcb1a ATP binding cassette subfamily B member 1A decreases activity EXP 1,9-dideoxyforskolin results in decreased activity of ABCB1A protein CTD PMID:12202523 NCBI chr 4:25,357,467...25,529,941
Ensembl chr 4:25,158,362...25,442,709
JBrowse link
G Abcb1b ATP-binding cassette, subfamily B (MDR/TAP), member 1B decreases activity EXP 1,9-dideoxyforskolin results in decreased activity of ABCB1B protein CTD PMID:12202523 NCBI chr 4:25,242,761...25,325,194
Ensembl chr 4:25,242,798...25,325,199
JBrowse link
G Abcb4 ATP binding cassette subfamily B member 4 decreases activity EXP 1,9-dideoxyforskolin results in decreased activity of ABCB4 protein CTD PMID:12202523 NCBI chr 4:25,150,998...25,209,489
Ensembl chr 4:25,151,953...25,209,202
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 20050
    role 20001
      biological role 20000
        antimicrobial agent 17759
          antiviral agent 10475
            anti-HIV agent 1274
              forskolin 4
                1,9-dideoxyforskolin 3
                colforsin daropate 0
                methylpiperazinoforskolin 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 20050
    subatomic particle 20048
      composite particle 20048
        hadron 20048
          baryon 20048
            nucleon 20048
              atomic nucleus 20048
                atom 20048
                  main group element atom 19948
                    p-block element atom 19948
                      carbon group element atom 19872
                        carbon atom 19863
                          organic molecular entity 19863
                            organic group 18937
                              organic divalent group 18922
                                organodiyl group 18922
                                  carbonyl group 18872
                                    carbonyl compound 18872
                                      ketone 17097
                                        oxyketone 8727
                                          alpha-oxyketone 8727
                                            alpha-hydroxy ketone 8727
                                              tertiary alpha-hydroxy ketone 8427
                                                forskolin 4
                                                  1,9-dideoxyforskolin 3
                                                  colforsin daropate 0
                                                  methylpiperazinoforskolin 0
paths to the root