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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:dithionite(2-)
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Accession:CHEBI:42160 term browser browse the term
Definition:A sulfur oxide that has formula O4S2.
Synonyms:exact_synonym: 2,3-dioxido-1,4-dioxy-2,3-disulfy-[4]catenate(2-);   bis(dioxidosulfate)(S--S)(2-)
 related_synonym: DITHIONITE;   Dithionit;   Formula=O4S2;   InChI=1S/H2O4S2/c1-5(2)6(3)4/h(H,1,2)(H,3,4)/p-2;   InChIKey=GRWZHXKQBITJKP-UHFFFAOYSA-L;   SMILES=[O-]S(=O)S([O-])=O;   [O2SSO2](2-);   [S2O4](2-)
 alt_id: CHEBI:29206;   CHEBI:42154
 xref: CAS:14844-07-6;   Gmelin:2516
 xref_mesh: MESH:D004227
 xref: PDBeChem:DTN
 cyclic_relationship: is_conjugate_base_of CHEBI:33487


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dithionite(2-) term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acp5 acid phosphatase 5, tartrate resistant decreases activity
multiple interactions
EXP Dithionite results in decreased activity of ACP5 protein
ferrous chloride inhibits the reaction [Dithionite results in decreased activity of ACP5 protein]
CTD PMID:6886379 NCBI chr 8:23,142,733...23,149,067
Ensembl chr 8:23,142,734...23,148,396
JBrowse link
G Akt1 AKT serine/threonine kinase 1 multiple interactions EXP 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [Quercetin inhibits the reaction [[Dithionite co-treated with Glucose deficiency] results in decreased phosphorylation of AKT1 protein]]; 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one promotes the reaction [[Dithionite co-treated with Glucose deficiency] results in decreased phosphorylation of AKT1 protein]; [Dithionite co-treated with Glucose deficiency] results in decreased phosphorylation of AKT1 protein; Quercetin inhibits the reaction [[Dithionite co-treated with Glucose deficiency] results in decreased phosphorylation of AKT1 protein] CTD PMID:21803128 NCBI chr 6:137,218,398...137,239,970
Ensembl chr 6:137,218,376...137,236,258
JBrowse link
G Bax BCL2 associated X, apoptosis regulator multiple interactions EXP [Dithionite co-treated with Glucose deficiency] results in increased expression of BAX protein; Quercetin inhibits the reaction [[Dithionite co-treated with Glucose deficiency] results in increased expression of BAX protein] CTD PMID:21803128 NCBI chr 1:101,451,801...101,457,207
Ensembl chr 1:101,451,802...101,457,207
JBrowse link
G Bcl2 BCL2, apoptosis regulator multiple interactions EXP 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [Quercetin inhibits the reaction [[Dithionite co-treated with Glucose deficiency] results in decreased expression of BCL2 protein]]; 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one promotes the reaction [[Dithionite co-treated with Glucose deficiency] results in decreased expression of BCL2 protein]; [Dithionite co-treated with Glucose deficiency] results in decreased expression of BCL2 protein; Quercetin inhibits the reaction [[Dithionite co-treated with Glucose deficiency] results in decreased expression of BCL2 protein] CTD PMID:21803128 NCBI chr13:26,605,426...26,769,374
Ensembl chr13:26,605,426...26,769,374
JBrowse link
G C5 complement C5 multiple interactions ISO Dithionite inhibits the reaction [Asbestos, Crocidolite results in increased cleavage of C5 protein]; Dithionite inhibits the reaction [Asbestos, Serpentine results in increased cleavage of C5 protein] CTD PMID:10777245 NCBI chr 3:14,049,993...14,113,931
NCBI chr 3:14,206,466...14,229,141
Ensembl chr 3:14,049,995...14,229,080
JBrowse link
G Casp3 caspase 3 multiple interactions EXP [Dithionite co-treated with Glucose deficiency] results in increased cleavage of CASP3 protein; Quercetin inhibits the reaction [[Dithionite co-treated with Glucose deficiency] results in increased expression of CASP3 protein] CTD PMID:21803128 NCBI chr16:48,845,011...48,863,249
Ensembl chr16:48,845,012...48,863,204
JBrowse link
G Gria2 glutamate ionotropic receptor AMPA type subunit 2 multiple interactions EXP [Dithionite co-treated with Glucose deficiency] results in decreased expression of GRIA2 protein; Genistein inhibits the reaction [[Dithionite co-treated with Glucose deficiency] results in decreased expression of GRIA2 protein] CTD PMID:27238724 NCBI chr 2:179,584,302...179,704,629
Ensembl chr 2:179,584,308...179,704,629
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19771
    chemical entity 19771
      molecular entity 19770
        inorganic molecular entity 19447
          inorganic oxide 7435
            sulfur oxide 587
              dithionite(2-) 7
                sodium dithionite 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 19771
    subatomic particle 19770
      composite particle 19770
        hadron 19770
          baryon 19770
            nucleon 19770
              atomic nucleus 19770
                atom 19770
                  main group element atom 19658
                    p-block element atom 19658
                      chalcogen 19387
                        oxygen atom 19350
                          oxygen molecular entity 19350
                            oxide 11711
                              oxoanion 8882
                                chalcogen oxoanion 534
                                  sulfur oxoanion 533
                                    dithionite(2-) 7
                                      sodium dithionite 0
paths to the root