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Accession:CHEBI:42142 term browser browse the term
Definition:A C-terminal boronic acid petide that is N-acetyl-D-phenylalanyl-L-prolyl-L-arginine in which the C-termnal carboxy group has been replaced by a borono (-B(OH)2) group. A thrombin (Factor IIa) inhibitor, thereby acting as an anticoagulant.
Synonyms:exact_synonym: N-acetyl-D-phenylalanyl-N-[(1R)-1-borono-4-carbamimidamidobutyl]-L-prolinamide
 related_synonym: Formula=C21H33BN6O5;   InChI=1S/C21H33BN6O5/c1-14(29)26-16(13-15-7-3-2-4-8-15)20(31)28-12-6-9-17(28)19(30)27-18(22(32)33)10-5-11-25-21(23)24/h2-4,7-8,16-18,32-33H,5-6,9-13H2,1H3,(H,26,29)(H,27,30)(H4,23,24,25)/t16-,17+,18+/m1/s1;   InChIKey=FXFYPTZERULUBS-SQNIBIBYSA-N;   SMILES=N([C@@H](CCCNC(N)=N)B(O)O)C(=O)[C@@H]1CCCN1C([C@@H](CC2=CC=CC=C2)NC(C)=O)=O;   acetylphenylalanyl-prolyl-boroarginine
 xref: CAS:130982-43-3 "ChemIDplus";   PDBeChem:DP7;   Reaxys:24287151 "Reaxys"
 cyclic_relationship: is_conjugate_base_of CHEBI:140518

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  CHEBI ontology 19679
    chemical entity 19677
      group 19592
        organic group 18351
          amino-acid residue 9298
            C-terminal boronic acid peptide 0
              Ac-(D)Phe-Pro-boroArg-OH 0
Path 2
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  CHEBI ontology 19679
    subatomic particle 19675
      composite particle 19675
        hadron 19675
          baryon 19675
            nucleon 19675
              atomic nucleus 19675
                atom 19675
                  main group element atom 19555
                    p-block element atom 19555
                      carbon group element atom 19438
                        carbon atom 19430
                          organic molecular entity 19430
                            organic group 18351
                              organic divalent group 18340
                                organodiyl group 18340
                                  carbonyl group 18225
                                    carbonyl compound 18225
                                      carboxylic acid 17930
                                        carboacyl group 16948
                                          univalent carboacyl group 16948
                                            carbamoyl group 16627
                                              carboxamide 16627
                                                peptide 9297
                                                  C-terminal boronic acid peptide 0
                                                    Ac-(D)Phe-Pro-boroArg-OH 0
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