Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   

ONTOLOGY REPORT - ANNOTATIONS


Term:digoxigenin
go back to main search page
Accession:CHEBI:42098 term browser browse the term
Definition:A hydroxy steroid that consists of 5beta-cardanolide having a double bond at the 20(22)-position as well as hydroxy groups at the 3beta-, 12beta- and 14beta-positions. It has been isolated from the plant species of the genus Digitalis.
Synonyms:exact_synonym: 3beta,12beta,14-trihydroxy-5beta-card-20(22)-enolide
 related_synonym: Formula=C23H34O5;   InChI=1S/C23H34O5/c1-21-7-5-15(24)10-14(21)3-4-17-18(21)11-19(25)22(2)16(6-8-23(17,22)27)13-9-20(26)28-12-13/h9,14-19,24-25,27H,3-8,10-12H2,1-2H3/t14-,15+,16-,17-,18+,19-,21+,22+,23+/m1/s1;   InChIKey=SHIBSTMRCDJXLN-KCZCNTNESA-N;   SMILES=[H][C@]12CC[C@]3([H])[C@]([H])(C[C@@H](O)[C@]4(C)[C@]([H])(CC[C@]34O)C3=CC(=O)OC3)[C@@]1(C)CC[C@H](O)C2
 alt_id: CHEBI:38020;   CHEBI:42096
 xref: CAS:1672-46-4 "ChemIDplus";   HMDB:HMDB0060731;   LIPID_MAPS_instance:LMST01120008 "LIPID MAPS"
 xref_mesh: MESH:D004076
 xref: PDBeChem:DOG;   PMID:10438974 "Europe PMC";   PMID:23344238 "Europe PMC";   PMID:23383657 "Europe PMC";   PMID:8080093 "Europe PMC";   PMID:9470094 "Europe PMC";   Wikipedia:Digoxigenin


show annotations for term's descendants       view all columns           Sort by:
 
digoxigenin term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Abcb1a ATP binding cassette subfamily B member 1A JBrowse link 4 22,339,829 22,517,642 RGD:6480464
G Ccl2 C-C motif chemokine ligand 2 JBrowse link 10 69,412,065 69,413,863 RGD:6480464
G Ccl4 C-C motif chemokine ligand 4 JBrowse link 10 70,870,926 70,886,357 RGD:6480464
G G6pc glucose-6-phosphatase, catalytic subunit JBrowse link 10 89,286,009 89,296,213 RGD:6480464
G Il17a interleukin 17A JBrowse link 9 26,841,299 26,844,786 RGD:6480464
G Il17f interleukin 17F JBrowse link 9 26,885,702 26,897,219 RGD:6480464
G Il6r interleukin 6 receptor JBrowse link 2 189,196,180 189,255,987 RGD:6480464
G Npas2 neuronal PAS domain protein 2 JBrowse link 9 45,901,262 46,081,880 RGD:6480464
G Rorc RAR-related orphan receptor C JBrowse link 2 195,612,471 195,636,797 RGD:6480464
G Vegfa vascular endothelial growth factor A JBrowse link 9 17,340,341 17,355,681 RGD:6480464

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19669
    role 19613
      biological role 19611
        hapten 2962
          digoxigenin 10
            20,22-dihydrodigoxigenin 0
            Dig-Cy5 0
            digoxigenin 3,12-diacetate 0
            digoxigenin monodigitoxoside 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 19669
    subatomic particle 19665
      composite particle 19665
        hadron 19665
          baryon 19665
            nucleon 19665
              atomic nucleus 19665
                atom 19665
                  main group element atom 19545
                    p-block element atom 19545
                      carbon group element atom 19428
                        carbon atom 19420
                          organic molecular entity 19420
                            organic group 18343
                              organic divalent group 18334
                                organodiyl group 18334
                                  carbonyl group 18222
                                    carbonyl compound 18222
                                      carboxylic ester 13934
                                        lactone 5859
                                          steroid lactone 361
                                            cardanolide 41
                                              5beta-cardanolide 41
                                                digoxigenin 10
                                                  20,22-dihydrodigoxigenin 0
                                                  Dig-Cy5 0
                                                  digoxigenin 3,12-diacetate 0
                                                  digoxigenin monodigitoxoside 0
paths to the root

NHLBI Logo

RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.