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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:dideuterium oxide
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Accession:CHEBI:41981 term browser browse the term
Definition:A water that has formula 20.02760.
Synonyms:related_synonym: ((2)H2)water;   D2O;   DEUTERATED WATER;   Deuteriumoxid;   Formula=D2O;   InChI=1S/H2O/h1H2/i/hD2;   InChIKey=XLYOFNOQVPJJNP-ZSJDYOACSA-N;   SMILES=[2H]O[2H];   [OD2];   deuterium oxide;   heavy water;   schweres Wasser
 alt_id: CHEBI:29373;   CHEBI:41979
 xref: CAS:7789-20-0;   Gmelin:97
 xref_mesh: MESH:D017666
 xref: MolBase:1647;   PDBeChem:DOD


show annotations for term's descendants           Sort by:
dideuterium oxide term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Akt1 AKT serine/threonine kinase 1 decreases phosphorylation
multiple interactions 		ISO Deuterium Oxide results in decreased phosphorylation of AKT1 protein
Acetylcysteine inhibits the reaction [Deuterium Oxide results in decreased phosphorylation of AKT1 protein] 		CTD PMID:37751786 NCBI chr 6:137,534,810...137,555,131
Ensembl chr 6:137,535,390...137,552,610 		JBrowse link
G Akt2 AKT serine/threonine kinase 2 decreases phosphorylation
multiple interactions 		ISO Deuterium Oxide results in decreased phosphorylation of AKT2 protein
Acetylcysteine inhibits the reaction [Deuterium Oxide results in decreased phosphorylation of AKT2 protein] 		CTD PMID:37751786 NCBI chr 1:92,004,705...92,061,420
Ensembl chr 1:92,014,859...92,061,420 		JBrowse link
G Akt3 AKT serine/threonine kinase 3 decreases phosphorylation
multiple interactions 		ISO Deuterium Oxide results in decreased phosphorylation of AKT3 protein
Acetylcysteine inhibits the reaction [Deuterium Oxide results in decreased phosphorylation of AKT3 protein] 		CTD PMID:37751786 NCBI chr13:91,475,839...91,758,060
Ensembl chr13:91,475,839...91,748,020 		JBrowse link
G Bax BCL2 associated X, apoptosis regulator increases expression ISO Deuterium Oxide results in increased expression of BAX protein CTD PMID:37751786 NCBI chr 1:105,076,472...105,081,906
Ensembl chr 1:105,076,473...105,086,429 		JBrowse link
G Becn1 beclin 1 increases expression
multiple interactions 		ISO Deuterium Oxide results in increased expression of BECN1 protein
Acetylcysteine inhibits the reaction [Deuterium Oxide results in increased expression of BECN1 protein] 		CTD PMID:37751786 NCBI chr10:86,731,649...86,747,002
Ensembl chr10:86,731,650...86,747,002 		JBrowse link
G Casp3 caspase 3 increases cleavage ISO Deuterium Oxide results in increased cleavage of CASP3 protein CTD PMID:37751786 NCBI chr16:52,395,539...52,413,794
Ensembl chr16:52,395,540...52,413,732 		JBrowse link
G Map1lc3b microtubule-associated protein 1 light chain 3 beta multiple interactions ISO Acetylcysteine inhibits the reaction [Deuterium Oxide results in increased expression of and results in increased lipidation of MAP1LC3B protein]; Deuterium Oxide results in increased expression of and results in increased lipidation of MAP1LC3B protein CTD PMID:37751786 NCBI chr19:66,571,631...66,582,270
Ensembl chr19:66,574,407...66,584,358
Ensembl chr16:66,574,407...66,584,358 		JBrowse link
G Mtor mechanistic target of rapamycin kinase decreases phosphorylation
multiple interactions 		ISO Deuterium Oxide results in decreased phosphorylation of MTOR protein
Acetylcysteine inhibits the reaction [Deuterium Oxide results in decreased phosphorylation of MTOR protein] 		CTD PMID:37751786 NCBI chr 5:164,167,985...164,277,438
Ensembl chr 5:164,167,928...164,277,435 		JBrowse link
G Pik3r1 phosphoinositide-3-kinase regulatory subunit 1 multiple interactions
decreases phosphorylation 		ISO Acetylcysteine inhibits the reaction [Deuterium Oxide results in decreased phosphorylation of PIK3R1 protein] CTD PMID:37751786 NCBI chr 2:34,612,946...34,697,660
Ensembl chr 2:34,612,946...34,626,347 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 20862
    role 20820
      chemical role 20396
        NMR chemical shift reference compound 18453
          dideuterium oxide 9
Path 2
Term Annotations click to browse term
  CHEBI ontology 20862
    subatomic particle 20860
      composite particle 20860
        hadron 20860
          baryon 20860
            nucleon 20860
              atomic nucleus 20860
                atom 20860
                  main group element atom 20781
                    main group molecular entity 20781
                      s-block molecular entity 20574
                        hydrogen molecular entity 20558
                          hydrides 19693
                            inorganic hydride 18602
                              chalcogen hydride 2939
                                oxygen hydride 815
                                  water 754
                                    dideuterium oxide 9
paths to the root