D-hexose 6-phosphate - Ontology Report

[Enzyme Inhibitors results in decreased activity of FBP1 protein] which results in decreased abundance of Glucose-6-Phosphate

NCBI chr13:63,012,567...63,036,112
Ensembl chr13:63,012,567...63,036,096

G6pc1

glucose-6-phosphatase catalytic subunit 1

multiple interactions

[Fluoxetine results in decreased expression of G6PC1 protein] which results in increased abundance of Glucose-6-Phosphate

PMID:33179799

NCBI chr11:101,258,542...101,268,729
Ensembl chr11:101,258,387...101,268,729

G6pc2

glucose-6-phosphatase, catalytic, 2

increases hydrolysis

ISO

G6PC2 protein results in increased hydrolysis of Glucose-6-Phosphate

PMID:14722102

NCBI chr 2:69,041,417...69,058,337
Ensembl chr 2:69,041,417...69,058,185

Gpd2

glycerol phosphate dehydrogenase 2, mitochondrial

multiple interactions

GPD2 protein inhibits the reaction [Dihydroxyacetone results in increased abundance of Glucose-6-Phosphate]; GPD2 protein inhibits the reaction [Glucose results in increased abundance of Glucose-6-Phosphate]; GPD2 protein inhibits the reaction [Glycerol results in increased abundance of Glucose-6-Phosphate]

NCBI chr 2:57,127,690...57,260,731
Ensembl chr 2:57,127,647...57,260,731

Nr4a1

nuclear receptor subfamily 4, group A, member 1

multiple interactions

[Glycerol co-treated with Succinic Acid co-treated with Glucose-6-Phosphate co-treated with Pantothenic Acid co-treated with Niacinamide] results in increased expression of NR4A1 mRNA

PMID:20505214

NCBI chr15:101,151,783...101,172,676
Ensembl chr15:101,152,150...101,172,676

Pfkfb1

6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1

increases abundance
multiple interactions

PFKFB1 gene mutant form results in increased abundance of Glucose-6-Phosphate
PFKFB1 gene mutant form inhibits the reaction [Metformin results in decreased abundance of Glucose-6-Phosphate metabolite]

NCBI chr X:149,370,441...149,426,874
Ensembl chr X:149,371,225...149,426,874

Prkaa1

protein kinase, AMP-activated, alpha 1 catalytic subunit

multiple interactions

[[PRKAA1 gene co-treated with PRKAA2 gene] affects the susceptibility to 4-hydroxy-3-(4-(2-hydroxyphenyl)phenyl)-6-oxo-7H-thieno(2,3-b)pyridine-5-carbonitrile] which results in increased abundance of Glucose-6-Phosphate; [[PRKAA1 gene mutant form co-treated with PRKAA2 gene mutant form] affects the susceptibility to [Glucose co-treated with S 4048]] which results in increased abundance of Glucose-6-Phosphate; [[PRKAA1 gene mutant form co-treated with PRKAA2 gene mutant form] affects the susceptibility to Metformin] which results in increased abundance of Glucose-6-Phosphate

NCBI chr15:5,172,641...5,211,380
Ensembl chr15:5,173,343...5,211,380

Prkaa2

protein kinase, AMP-activated, alpha 2 catalytic subunit

multiple interactions

NCBI chr 4:104,886,846...104,967,095
Ensembl chr 4:104,887,071...104,967,087

D-mannopyranose 6-phosphate

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

Cyp1a1

cytochrome P450, family 1, subfamily a, polypeptide 1

multiple interactions

ISO

mannose-6-phosphate affects the reaction [GUSB protein affects the reaction [Benzo(a)pyrene results in increased expression of CYP1A1 mRNA]]

PMID:26438400

NCBI chr 9:57,595,211...57,611,107
Ensembl chr 9:57,595,211...57,611,107

Gusb

glucuronidase, beta

multiple interactions

ISO

mannose-6-phosphate affects the reaction [GUSB protein affects the reaction [Benzo(a)pyrene results in increased expression of CYP1A1 mRNA]]