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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:decamethonium
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Accession:CHEBI:41934 term browser browse the term
Definition:A quaternary ammonium ion that is a depolarising muscle relaxant whose structure comprises a decane-1,10-diamine core in which each amino group carries three methyl substituents.
Synonyms:exact_synonym: N,N,N,N',N',N'-hexamethyldecane-1,10-diaminium
 related_synonym: DECAMETHONIUM ION;   Formula=C16H38N2;   InChI=1S/C16H38N2/c1-17(2,3)15-13-11-9-7-8-10-12-14-16-18(4,5)6/h7-16H2,1-6H3/q+2;   InChIKey=MTCUAOILFDZKCO-UHFFFAOYSA-N;   N,N,N,N',N',N'-hexamethyl-1,10-decanediaminium;   SMILES=C[N+](C)(C)CCCCCCCCCC[N+](C)(C)C;   decamethylenebis(trimethylammonium)
 alt_id: CHEBI:41930;   CHEBI:4346
 xref: Beilstein:1774794;   CAS:156-74-1;   DrugBank:DB01245;   Drug_Central:789;   HMDB:HMDB0015375;   KEGG:C11733;   LINCS:LSM-6606
 xref_mesh: MESH:C033019
 xref: PDBeChem:DME;   PMID:23398375;   PMID:6196640;   PMID:7678947;   Reaxys:1774794;   Wikipedia:Decamethonium


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decamethonium term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bche butyrylcholinesterase decreases activity ISO decamethonium results in decreased activity of BCHE protein CTD PMID:31173753 NCBI chr 3:73,543,138...73,615,767
Ensembl chr 3:73,543,141...73,615,748 		JBrowse link
G Chrna4 cholinergic receptor, nicotinic, alpha polypeptide 4 multiple interactions ISO Carbachol inhibits the reaction [decamethonium binds to and results in decreased activity of [CHRNA4 protein binds to CHRNB2 protein]]; decamethonium binds to and results in decreased activity of [CHRNA4 protein binds to CHRNB2 protein]; decamethonium inhibits the reaction [epibatidine binds to [CHRNA4 protein binds to CHRNB2 protein]]; decamethonium results in decreased activity of [CHRNA4 protein binds to CHRNB2 protein] CTD PMID:14645658 NCBI chr 2:180,664,104...180,685,339
Ensembl chr 2:180,660,173...180,685,339 		JBrowse link
G Chrnb2 cholinergic receptor nicotinic beta 2 subunit multiple interactions ISO Carbachol inhibits the reaction [decamethonium binds to and results in decreased activity of [CHRNA4 protein binds to CHRNB2 protein]]; decamethonium binds to and results in decreased activity of [CHRNA4 protein binds to CHRNB2 protein]; decamethonium inhibits the reaction [epibatidine binds to [CHRNA4 protein binds to CHRNB2 protein]]; decamethonium results in decreased activity of [CHRNA4 protein binds to CHRNB2 protein] CTD PMID:14645658 NCBI chr 3:89,660,755...89,671,939
Ensembl chr 3:89,653,502...89,671,939 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 22178
    chemical entity 22208
      molecular entity 22169
        ion 17696
          organic ion 10063
            organic cation 9099
              quaternary ammonium ion 5407
                decamethonium 3
Path 2
Term Annotations click to browse term
  CHEBI ontology 22178
    subatomic particle 22170
      composite particle 22170
        hadron 22201
          baryon 22170
            nucleon 22170
              atomic nucleus 22170
                atom 22170
                  main group element atom 22104
                    main group molecular entity 22104
                      s-block molecular entity 21729
                        hydrogen molecular entity 21646
                          hydrides 20758
                            inorganic hydride 18672
                              pnictogen hydride 18652
                                nitrogen hydride 18519
                                  ammonium 8211
                                    ammonium ion derivative 8196
                                      quaternary ammonium ion 5407
                                        decamethonium 3
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