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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:dexamethasone
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Accession:CHEBI:41879 term browser browse the term
Definition:A fluorinated steroid that is 9-fluoropregna-1,4-diene substituted by hydroxy groups at positions 11, 17 and 21, a methyl group at position 16 and oxo groups at positions 3 and 20. It is a synthetic member of the class of glucocorticoids.
Synonyms:exact_synonym: 9-fluoro-11beta,17,21-trihydroxy-16alpha-methylpregna-1,4-diene-3,20-dione
 related_synonym: (11beta,16alpha)-9-fluoro-11,17,21-trihydroxy-16-methylpregna-1,4-diene-3,20-dione;   1-dehydro-16alpha-methyl-9alpha-fluorohydrocortisone;   16alpha-methyl-9alpha-fluoro-1-dehydrocortisol;   9alpha-fluoro-16alpha-methylprednisolone;   Aeroseb-Dex;   Auxiron;   Azium;   Calonat;   Corson;   Cortisumman;   Decacort;   Decadron;   Decaject;   Decalix;   Decameth;   DexPak;   Dexacortal;   Dexacortin;   Dexason;   Dexasone;   Diodex;   Formula=C22H29FO5;   Hexadrol;   InChI=1S/C22H29FO5/c1-12-8-16-15-5-4-13-9-14(25)6-7-19(13,2)21(15,23)17(26)10-20(16,3)22(12,28)18(27)11-24/h6-7,9,12,15-17,24,26,28H,4-5,8,10-11H2,1-3H3/t12-,15+,16+,17+,19+,20+,21+,22+/m1/s1;   InChIKey=UREBDLICKHMUKA-CXSFZGCWSA-N;   Maxidex;   Millicorten;   Oradexon;   Ozurdex;   SMILES=C1=CC(C=C2[C@]1([C@@]3([C@@](CC2)([C@]4([C@](C[C@@H]3O)([C@]([C@@H](C4)C)(C(CO)=O)O)C)[H])[H])F)C)=O;   Solurex;   Zema-Pak;   dexametasona;   dexamethasonum;   fluormethylprednisolone
 alt_id: CHEBI:41873;   CHEBI:4461
 xref: Beilstein:2066652;   CAS:50-02-2;   DrugBank:DB01234;   Drug_Central:824;   FooDB:FDB001355;   HMDB:HMDB0015364;   KEGG:C15643;   KEGG:D00292
 xref_mesh: MESH:D003907
 xref: MetaCyc:CPD-10549;   PMID:11508649;   PMID:12151000;   PMID:12686538;   PMID:18272184;   PMID:18524938;   PMID:19779450;   PMID:20850457;   PMID:26602186;   PMID:29958267;   PMID:31391291;   PMID:32195984;   PMID:32280693;   PMID:32496907;   PMID:32551464;   PMID:32570995;   Patent:DE1113690;   Patent:GB869511;   Patent:US3007923;   Reaxys:2066652;   VSDB:1769;   Wikipedia:Dexamethasone



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      CHEBI ontology 19874
        role 19844
          biological role 19842
            xenobiotic 18722
              dexamethasone 4580
                dexamethasone phosphate 20
                dexamethasone sodium m-sulfobenzoate 0
    Path 2
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      CHEBI ontology 19874
        subatomic particle 19872
          composite particle 19872
            hadron 19872
              baryon 19872
                nucleon 19872
                  atomic nucleus 19872
                    atom 19872
                      main group element atom 19811
                        p-block element atom 19811
                          carbon group element atom 19751
                            carbon atom 19748
                              organic molecular entity 19748
                                heteroorganic entity 19505
                                  organochalcogen compound 19268
                                    organooxygen compound 19184
                                      carbonyl compound 18908
                                        ketone 17258
                                          oxo steroid 10532
                                            3-oxo steroid 9922
                                              3-oxo-Delta(1) steroid 5223
                                                3-oxo-Delta(1),Delta(4)-steroid 5223
                                                  dexamethasone 4580
                                                    dexamethasone phosphate 20
                                                    dexamethasone sodium m-sulfobenzoate 0
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