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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:sebacic acid
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Accession:CHEBI:41865 term browser browse the term
Definition:An alpha,omega-dicarboxylic acid that is the 1,8-dicarboxy derivative of octane.
Synonyms:related_synonym: 1,10-decanedioic acid;   1,8-dicarboxyoctane;   Decanedioic acid;   Formula=C10H18O4;   InChI=1S/C10H18O4/c11-9(12)7-5-3-1-2-4-6-8-10(13)14/h1-8H2,(H,11,12)(H,13,14);   InChIKey=CXMXRPHRNRROMY-UHFFFAOYSA-N;   SMILES=OC(=O)CCCCCCCCC(O)=O;   Sebacinsaeure
 alt_id: CHEBI:41860;   CHEBI:9071
 xref: Beilstein:1210591;   CAS:111-20-6;   DrugBank:DB07645;   Gmelin:102423;   HMDB:HMDB0000792;   KEGG:C08277;   KNApSAcK:C00001202;   LIPID_MAPS_instance:LMFA01170006
 xref_mesh: MESH:C011107
 xref: MetaCyc:CPD-3623;   PDBeChem:DEC;   PMID:22770225;   PMID:9439441;   Reaxys:1210591;   Wikipedia:Sebacic_acid
 cyclic_relationship: is_conjugate_acid_of CHEBI:132954;   is_conjugate_acid_of CHEBI:76283


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sebacic acid term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adh5 alcohol dehydrogenase 5 (class III), chi polypeptide multiple interactions ISO sebacic acid inhibits the reaction [ADH5 protein results in increased reduction of S-Nitrosoglutathione] CTD PMID:19428350 NCBI chr 2:226,975,184...226,987,591
Ensembl chr 2:226,947,466...226,987,591 		JBrowse link
G Ins2 insulin 2 multiple interactions ISO [1-Methyl-3-isobutylxanthine co-treated with butylbenzyl phthalate co-treated with INS protein] results in increased abundance of sebacic acid analog; [1-Methyl-3-isobutylxanthine co-treated with Dexamethasone co-treated with INS protein] results in increased abundance of sebacic acid analog CTD PMID:26820058 NCBI chr 1:197,843,277...197,992,522
Ensembl chr 1:197,843,281...197,864,775 		JBrowse link
G Nfe2l2 NFE2 like bZIP transcription factor 2 increases activity ISO sebacic acid results in increased activity of NFE2L2 protein CTD PMID:30114225 NCBI chr 3:60,594,239...60,621,712
Ensembl chr 3:60,594,242...60,621,737 		JBrowse link
G Stat5b signal transducer and activator of transcription 5B decreases activity ISO sebacic acid results in decreased activity of STAT5B protein CTD PMID:30114225 NCBI chr10:85,704,841...85,775,856
Ensembl chr10:85,705,670...85,775,668 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19876
    role 19851
      biological role 19849
        biochemical role 19543
          metabolite 19529
            eukaryotic metabolite 19342
              plant metabolite 17926
                sebacic acid 4
                  3-hydroxysebacic acid 0
                  decanedioyl-CoA 0
                  dimethyl sebacate 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 19876
    subatomic particle 19874
      composite particle 19874
        hadron 19874
          baryon 19874
            nucleon 19874
              atomic nucleus 19905
                atom 19905
                  main group element atom 19821
                    p-block element atom 19821
                      carbon group element atom 19768
                        carbon atom 19764
                          organic molecular entity 19764
                            organic group 18962
                              organic divalent group 18943
                                organodiyl group 18915
                                  carbonyl group 18869
                                    carbonyl compound 18869
                                      carboxylic acid 18618
                                        monocarboxylic acid 17917
                                          fatty acid 16580
                                            fatty acid derivative 8912
                                              dicarboxylic fatty acid 2645
                                                sebacic acid 4
                                                  3-hydroxysebacic acid 0
                                                  decanedioyl-CoA 0
                                                  dimethyl sebacate 0
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