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The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at The data is made available under the Creative Commons License (CC BY 3.0, For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:sebacic acid
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Accession:CHEBI:41865 term browser browse the term
Definition:An alpha,omega-dicarboxylic acid that is the 1,8-dicarboxy derivative of octane.
Synonyms:related_synonym: 1,10-decanedioic acid;   1,8-dicarboxyoctane;   Decanedioic acid;   Formula=C10H18O4;   InChI=1S/C10H18O4/c11-9(12)7-5-3-1-2-4-6-8-10(13)14/h1-8H2,(H,11,12)(H,13,14);   InChIKey=CXMXRPHRNRROMY-UHFFFAOYSA-N;   SMILES=OC(=O)CCCCCCCCC(O)=O;   Sebacinsaeure
 alt_id: CHEBI:41860;   CHEBI:9071
 xref: Beilstein:1210591;   CAS:111-20-6;   DrugBank:DB07645;   Gmelin:102423;   HMDB:HMDB0000792;   KEGG:C08277;   KNApSAcK:C00001202;   LIPID_MAPS_instance:LMFA01170006
 xref_mesh: MESH:C011107
 xref: MetaCyc:CPD-3623;   PDBeChem:DEC;   PMID:22770225;   PMID:9439441;   Reaxys:1210591;   Wikipedia:Sebacic_acid
 cyclic_relationship: is_conjugate_acid_of CHEBI:132954;   is_conjugate_acid_of CHEBI:76283

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sebacic acid term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adh5 alcohol dehydrogenase 5 (class III), chi polypeptide multiple interactions ISO sebacic acid inhibits the reaction [ADH5 protein results in increased reduction of S-Nitrosoglutathione] CTD PMID:19428350 NCBI chr 2:243,728,500...243,740,907
Ensembl chr 2:243,700,784...243,740,899
JBrowse link
G Ins2 insulin 2 multiple interactions ISO [1-Methyl-3-isobutylxanthine co-treated with butylbenzyl phthalate co-treated with INS protein] results in increased abundance of sebacic acid analog; [1-Methyl-3-isobutylxanthine co-treated with Dexamethasone co-treated with INS protein] results in increased abundance of sebacic acid analog CTD PMID:26820058 NCBI chr 1:215,856,967...215,858,034
Ensembl chr 1:215,856,971...215,858,034
JBrowse link
G Nfe2l2 nuclear factor, erythroid 2-like 2 increases activity ISO sebacic acid results in increased activity of NFE2L2 protein CTD PMID:30114225 NCBI chr 3:62,497,568...62,525,146
Ensembl chr 3:62,497,571...62,524,996
JBrowse link
G Stat5b signal transducer and activator of transcription 5B decreases activity ISO sebacic acid results in decreased activity of STAT5B protein CTD PMID:30114225 NCBI chr10:88,686,207...88,712,313
Ensembl chr10:88,686,207...88,754,829
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19787
    role 19734
      biological role 19734
        biochemical role 19282
          metabolite 19263
            eukaryotic metabolite 18908
              plant metabolite 17360
                sebacic acid 4
                  3-hydroxysebacic acid 0
                  decanedioyl-CoA 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 19787
    subatomic particle 19784
      composite particle 19784
        hadron 19784
          baryon 19784
            nucleon 19784
              atomic nucleus 19784
                atom 19784
                  main group element atom 19672
                    p-block element atom 19672
                      carbon group element atom 19574
                        carbon atom 19563
                          organic molecular entity 19563
                            organic group 18495
                              organic divalent group 18488
                                organodiyl group 18488
                                  carbonyl group 18391
                                    carbonyl compound 18391
                                      dicarboxylic acids and O-substituted derivatives 10272
                                        dicarboxylic acid 10265
                                          alpha,omega-dicarboxylic acid 2774
                                            sebacic acid 4
                                              3-hydroxysebacic acid 0
                                              decanedioyl-CoA 0
paths to the root


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.