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The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at The data is made available under the Creative Commons License (CC BY 3.0, For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:4,4'-dipyridyl disulfide
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Accession:CHEBI:41814 term browser browse the term
Definition:An organic disulfide obtained by formal oxidative dimerisation of 4-thiopyridine.
Synonyms:exact_synonym: 4,4'-disulfanediyldipyridine
 related_synonym: 4,4'-Dipyridine disulfide;   4,4'-dithiodipyridine;   4-Pyridyl disulfide;   Aldrithiol-4;   Bis(4-pyridyl) disulfide;   Di(4-pyridyl) disulfide;   Formula=C10H8N2S2;   InChI=1S/C10H8N2S2/c1-5-11-6-2-9(1)13-14-10-3-7-12-8-4-10/h1-8H;   InChIKey=UHBAPGWWRFVTFS-UHFFFAOYSA-N;   SMILES=S(Sc1ccncc1)c1ccncc1
 xref: CAS:2645-22-9;   DrugBank:DB07623
 xref_mesh: MESH:C007542
 xref: MetaCyc:CPD-9046;   PDBeChem:D4G;   PMID:4025805;   Reaxys:154742

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4,4'-dipyridyl disulfide term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Keap1 Kelch-like ECH-associated protein 1 multiple interactions ISO 4,4'-dipyridyl disulfide inhibits the reaction [5,5'-bis(8-(phenylamino)-1-naphthalenesulfonate) binds to KEAP1 protein]; 4,4'-dipyridyl disulfide promotes the reaction [4-(2-pyridylazo)resorcinol inhibits the reaction [Zinc binds to KEAP1 protein]] CTD PMID:15865434 NCBI chr 8:22,250,518...22,259,868
Ensembl chr 8:22,250,518...22,259,779
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G Mgmt O-6-methylguanine-DNA methyltransferase affects binding ISO 4,4'-dipyridyl disulfide binds to MGMT protein CTD PMID:12974631 NCBI chr 1:209,237,255...209,464,189
Ensembl chr 1:209,237,233...209,464,190
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Term paths to the root
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  CHEBI ontology 19853
    chemical entity 19853
      atom 19851
        nonmetal atom 19733
          sulfur atom 16303
            sulfur molecular entity 16303
              organosulfur compound 15234
                organic disulfide 752
                  4,4'-dipyridyl disulfide 2
Path 2
Term Annotations click to browse term
  CHEBI ontology 19853
    subatomic particle 19851
      composite particle 19851
        hadron 19851
          baryon 19851
            nucleon 19851
              atomic nucleus 19851
                atom 19851
                  main group element atom 19744
                    p-block element atom 19744
                      carbon group element atom 19650
                        carbon atom 19639
                          organic molecular entity 19639
                            organic molecule 19568
                              organic cyclic compound 19378
                                organic heterocyclic compound 18495
                                  organic heteromonocyclic compound 16597
                                    pyridines 8412
                                      4,4'-dipyridyl disulfide 2
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