|
G |
Ache |
acetylcholinesterase |
multiple interactions |
ISO |
acanthoside B inhibits the reaction [Scopolamine results in increased expression of ACHE protein] |
CTD |
PMID:31077737 |
|
NCBI chr12:19,406,133...19,413,713
Ensembl chr12:19,407,360...19,413,651
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G |
Bdnf |
brain-derived neurotrophic factor |
multiple interactions |
ISO |
[acanthoside B co-treated with Scopolamine] results in increased expression of BDNF protein |
CTD |
PMID:31077737 |
|
NCBI chr 3:96,165,042...96,215,621
Ensembl chr 3:96,165,042...96,215,615
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|
G |
Cat |
catalase |
multiple interactions |
ISO |
acanthoside B inhibits the reaction [Scopolamine results in decreased activity of CAT protein] |
CTD |
PMID:31077737 |
|
NCBI chr 3:89,842,393...89,874,577
Ensembl chr 3:89,842,399...89,874,478
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|
G |
Creb1 |
cAMP responsive element binding protein 1 |
multiple interactions |
ISO |
acanthoside B inhibits the reaction [Scopolamine results in decreased phosphorylation of CREB1 protein] |
CTD |
PMID:31077737 |
|
NCBI chr 9:65,903,511...65,972,562
Ensembl chr 9:65,903,547...65,970,816
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G |
Il10 |
interleukin 10 |
multiple interactions |
ISO |
acanthoside B inhibits the reaction [Scopolamine results in decreased expression of IL10 protein] |
CTD |
PMID:31077737 |
|
NCBI chr13:42,472,625...42,477,308
Ensembl chr13:42,472,839...42,477,313
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G |
Il1b |
interleukin 1 beta |
multiple interactions |
ISO |
acanthoside B inhibits the reaction [Scopolamine results in increased expression of IL1B protein] |
CTD |
PMID:31077737 |
|
NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415
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G |
Il6 |
interleukin 6 |
multiple interactions |
ISO |
acanthoside B inhibits the reaction [Scopolamine results in increased expression of IL6 protein] |
CTD |
PMID:31077737 |
|
NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178
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|
G |
Nos2 |
nitric oxide synthase 2 |
multiple interactions |
ISO |
acanthoside B inhibits the reaction [Scopolamine results in increased expression of NOS2 protein] |
CTD |
PMID:31077737 |
|
NCBI chr10:63,815,308...63,851,208
Ensembl chr10:63,815,308...63,851,210
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|
G |
Ntrk2 |
neurotrophic receptor tyrosine kinase 2 |
multiple interactions |
ISO |
[acanthoside B co-treated with Scopolamine] results in increased phosphorylation of NTRK2 protein |
CTD |
PMID:31077737 |
|
NCBI chr17:5,558,992...5,870,299
Ensembl chr17:5,559,043...5,869,136
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|
G |
Ptgs2 |
prostaglandin-endoperoxide synthase 2 |
multiple interactions |
ISO |
acanthoside B inhibits the reaction [Scopolamine results in increased expression of PTGS2 protein] |
CTD |
PMID:31077737 |
|
NCBI chr13:62,163,936...62,172,193
Ensembl chr13:62,163,932...62,172,188
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|
G |
Tnf |
tumor necrosis factor |
multiple interactions |
ISO |
acanthoside B inhibits the reaction [Scopolamine results in increased expression of TNF protein] |
CTD |
PMID:31077737 |
|
NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629
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|
|
G |
Fos |
Fos proto-oncogene, AP-1 transcription factor subunit |
increases expression |
ISO |
ginsenoside Rh1 results in increased expression of FOS mRNA |
CTD |
PMID:16204943 |
|
NCBI chr 6:105,121,170...105,124,036
Ensembl chr 6:105,121,170...105,124,036
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|
G |
Icam1 |
intercellular adhesion molecule 1 |
multiple interactions |
ISO |
ginsenoside Rh1 inhibits the reaction [TNF protein results in increased expression of ICAM1 protein] |
CTD |
PMID:21875580 |
|
NCBI chr 8:19,553,063...19,565,438
Ensembl chr 8:19,553,645...19,565,438
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|
G |
Il1b |
interleukin 1 beta |
multiple interactions |
ISO |
ginsenoside Rh1 inhibits the reaction [Oxazolone results in increased expression of IL1B mRNA]; ginsenoside Rh1 inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of IL1B mRNA] |
CTD |
PMID:16557482 |
|
NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415
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G |
Il4 |
interleukin 4 |
decreases expression |
ISO |
ginsenoside Rh1 results in decreased expression of IL4 |
CTD |
PMID:22855946 |
|
NCBI chr10:37,771,203...37,776,750
Ensembl chr10:37,771,203...37,776,750
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G |
Il6 |
interleukin 6 |
multiple interactions |
ISO |
ginsenoside Rh1 inhibits the reaction [Galactose results in increased secretion of IL6 protein] |
CTD |
PMID:29412148 |
|
NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178
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G |
Itga4 |
integrin subunit alpha 4 |
multiple interactions |
ISO |
ginsenoside Rh1 inhibits the reaction [TNF protein results in increased expression of [ITGA4 protein binds to ITGB1 protein]] |
CTD |
PMID:21875580 |
|
NCBI chr 3:64,162,764...64,235,010
Ensembl chr 3:64,163,085...64,233,715
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G |
Itgal |
integrin subunit alpha L |
multiple interactions |
ISO |
ginsenoside Rh1 inhibits the reaction [TNF protein results in increased expression of [ITGAL protein binds to ITGB2 protein]] |
CTD |
PMID:21875580 |
|
NCBI chr 1:181,918,183...181,955,735
Ensembl chr 1:181,918,183...181,955,732
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G |
Itgb1 |
integrin subunit beta 1 |
multiple interactions |
ISO |
ginsenoside Rh1 inhibits the reaction [TNF protein results in increased expression of [ITGA4 protein binds to ITGB1 protein]] |
CTD |
PMID:21875580 |
|
NCBI chr19:56,705,123...56,753,199
Ensembl chr19:56,705,171...56,753,195
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G |
Itgb2 |
integrin subunit beta 2 |
multiple interactions |
ISO |
ginsenoside Rh1 inhibits the reaction [TNF protein results in increased expression of [ITGAL protein binds to ITGB2 protein]] |
CTD |
PMID:21875580 |
|
NCBI chr20:11,061,394...11,097,656
Ensembl chr20:11,061,430...11,097,600
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G |
Jun |
Jun proto-oncogene, AP-1 transcription factor subunit |
decreases activity |
ISO |
ginsenoside Rh1 results in decreased activity of JUN protein |
CTD |
PMID:22855946 |
|
NCBI chr 5:109,894,175...109,897,268
Ensembl chr 5:109,893,145...109,897,656
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G |
Lpl |
lipoprotein lipase |
increases secretion |
ISO |
ginsenoside Rh1 results in increased secretion of LPL protein |
CTD |
PMID:8988629 |
|
NCBI chr16:20,830,055...20,853,855
Ensembl chr16:20,829,465...20,855,249
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|
G |
Pgr |
progesterone receptor |
increases expression |
ISO |
ginsenoside Rh1 results in increased expression of PGR protein |
CTD |
PMID:16204943 |
|
NCBI chr 8:6,072,673...6,131,552
Ensembl chr 8:6,072,673...6,131,344
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G |
Pparg |
peroxisome proliferator-activated receptor gamma |
multiple interactions |
ISO |
ginsenoside Rh1 inhibits the reaction [bisphenol A results in increased expression of PPARG mRNA]; ginsenoside Rh1 inhibits the reaction [bisphenol A results in increased expression of PPARG protein] |
CTD |
PMID:32623698 |
|
NCBI chr 4:148,423,102...148,548,471
Ensembl chr 4:148,423,194...148,548,468
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|
G |
Ptgs2 |
prostaglandin-endoperoxide synthase 2 |
multiple interactions |
ISO |
ginsenoside Rh1 inhibits the reaction [Oxazolone results in increased expression of PTGS2 mRNA]; ginsenoside Rh1 inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of PTGS2 mRNA] |
CTD |
PMID:16557482 |
|
NCBI chr13:62,163,936...62,172,193
Ensembl chr13:62,163,932...62,172,188
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G |
Sele |
selectin E |
multiple interactions |
ISO |
ginsenoside Rh1 inhibits the reaction [TNF protein results in increased expression of SELE protein] |
CTD |
PMID:21875580 |
|
NCBI chr13:76,402,841...76,412,741
Ensembl chr13:76,403,304...76,412,741
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G |
Tff1 |
trefoil factor 1 |
increases expression |
ISO |
ginsenoside Rh1 results in increased expression of TFF1 mRNA |
CTD |
PMID:16204943 |
|
NCBI chr20:9,235,736...9,239,597
Ensembl chr20:9,235,736...9,239,597
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|
G |
Tnf |
tumor necrosis factor |
multiple interactions decreases expression decreases response to substance |
ISO |
ginsenoside Rh1 inhibits the reaction [TNF protein results in increased expression of [ITGA4 protein binds to ITGB1 protein]]; ginsenoside Rh1 inhibits the reaction [TNF protein results in increased expression of [ITGAL protein binds to ITGB2 protein]]; ginsenoside Rh1 inhibits the reaction [TNF protein results in increased expression of ICAM1 protein]; ginsenoside Rh1 inhibits the reaction [TNF protein results in increased expression of SELE protein]; ginsenoside Rh1 inhibits the reaction [TNF protein results in increased expression of VCAM1 protein] ginsenoside Rh1 inhibits the reaction [Oxazolone results in increased expression of TNF mRNA]; ginsenoside Rh1 inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of TNF mRNA] ginsenoside Rh1 results in decreased expression of TNF ginsenoside Rh1 results in decreased susceptibility to TNF protein |
CTD |
PMID:16557482 PMID:21875580 PMID:22855946 |
|
NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629
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|
G |
Vcam1 |
vascular cell adhesion molecule 1 |
multiple interactions |
ISO |
ginsenoside Rh1 inhibits the reaction [TNF protein results in increased expression of VCAM1 protein] |
CTD |
PMID:21875580 |
|
NCBI chr 2:204,038,120...204,057,852
Ensembl chr 2:204,038,114...204,057,958
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|
G |
Akt1 |
AKT serine/threonine kinase 1 |
decreases phosphorylation |
ISO |
ginsenoside Rh2 results in decreased phosphorylation of AKT1 protein |
CTD |
PMID:32762018 |
|
NCBI chr 6:131,713,716...131,735,319
Ensembl chr 6:131,713,720...131,733,921
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|
G |
Bax |
BCL2 associated X, apoptosis regulator |
increases expression |
ISO |
ginsenoside Rh2 results in increased expression of BAX protein |
CTD |
PMID:26482938 PMID:32762018 |
|
NCBI chr 1:95,940,001...95,945,407
Ensembl chr 1:95,938,808...95,945,368
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|
G |
Bcl2 |
BCL2, apoptosis regulator |
decreases expression |
ISO |
ginsenoside Rh2 results in decreased expression of BCL2 protein |
CTD |
PMID:26482938 PMID:32762018 |
|
NCBI chr13:22,689,783...22,853,920
Ensembl chr13:22,684,989...22,853,743 Ensembl chr13:22,684,989...22,853,743
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G |
Casp3 |
caspase 3 |
increases cleavage decreases expression |
ISO |
ginsenoside Rh2 results in increased cleavage of CASP3 protein ginsenoside Rh2 results in decreased expression of CASP3 protein |
CTD |
PMID:26482938 PMID:32762018 |
|
NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648
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G |
Casp9 |
caspase 9 |
decreases expression |
ISO |
ginsenoside Rh2 results in decreased expression of CASP9 protein |
CTD |
PMID:32762018 |
|
NCBI chr 5:154,108,872...154,126,628
Ensembl chr 5:154,109,046...154,126,626
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G |
Ccnd1 |
cyclin D1 |
decreases expression |
ISO |
ginsenoside Rh2 results in decreased expression of CCND1 protein |
CTD |
PMID:26482938 |
|
NCBI chr 1:200,089,002...200,098,524
Ensembl chr 1:200,089,002...200,098,602
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G |
Hdac1 |
histone deacetylase 1 |
decreases expression |
ISO |
ginsenoside Rh2 results in decreased expression of HDAC1 protein |
CTD |
PMID:26482938 |
|
NCBI chr 5:141,853,992...141,881,057
Ensembl chr 5:141,853,989...141,881,111
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G |
Hdac2 |
histone deacetylase 2 |
decreases expression |
ISO |
ginsenoside Rh2 results in decreased expression of HDAC2 protein |
CTD |
PMID:26482938 |
|
NCBI chr20:40,548,244...40,571,609
Ensembl chr20:40,548,250...40,571,609
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G |
Hdac6 |
histone deacetylase 6 |
decreases expression |
ISO |
ginsenoside Rh2 results in decreased expression of HDAC6 protein |
CTD |
PMID:26482938 |
|
NCBI chr X:14,550,645...14,572,445
Ensembl chr X:14,551,044...14,572,441
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G |
Il6 |
interleukin 6 |
multiple interactions |
ISO |
ginsenoside Rh2 inhibits the reaction [Galactose results in increased secretion of IL6 protein] |
CTD |
PMID:29412148 |
|
NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178
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G |
Mapk1 |
mitogen activated protein kinase 1 |
decreases phosphorylation increases phosphorylation |
ISO |
ginsenoside Rh2 results in decreased phosphorylation of MAPK1 protein ginsenoside Rh2 results in increased phosphorylation of MAPK1 protein |
CTD |
PMID:26482938 PMID:32762018 |
|
NCBI chr11:83,957,813...84,023,629
Ensembl chr11:83,957,813...84,023,616
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G |
Mapk3 |
mitogen activated protein kinase 3 |
decreases phosphorylation increases phosphorylation |
ISO |
ginsenoside Rh2 results in decreased phosphorylation of MAPK3 protein ginsenoside Rh2 results in increased phosphorylation of MAPK3 protein |
CTD |
PMID:26482938 PMID:32762018 |
|
NCBI chr 1:181,366,646...181,372,863
Ensembl chr 1:181,366,637...181,372,863
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G |
Mtor |
mechanistic target of rapamycin kinase |
decreases phosphorylation |
ISO |
ginsenoside Rh2 results in decreased phosphorylation of MTOR protein |
CTD |
PMID:32762018 |
|
NCBI chr 5:158,884,856...158,994,311
Ensembl chr 5:158,884,804...158,994,311
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G |
Nfkbia |
NFKB inhibitor alpha |
increases expression |
ISO |
ginsenoside Rh2 results in increased expression of NFKBIA protein |
CTD |
PMID:32762018 |
|
NCBI chr 6:72,858,713...72,861,941
Ensembl chr 6:72,858,712...72,861,941
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G |
Rela |
RELA proto-oncogene, NF-kB subunit |
multiple interactions |
ISO |
ginsenoside Rh2 results in increased expression of and results in decreased phosphorylation of RELA protein |
CTD |
PMID:32762018 |
|
NCBI chr 1:202,925,001...202,935,484
Ensembl chr 1:202,924,945...202,935,484
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G |
Acta2 |
actin alpha 2, smooth muscle |
multiple interactions |
ISO |
Amygdalin inhibits the reaction [TGFB1 protein results in increased expression of ACTA2 mRNA]; Amygdalin inhibits the reaction [TGFB1 protein results in increased expression of ACTA2 protein] |
CTD |
PMID:36457260 |
|
NCBI chr 1:231,746,527...231,759,307
Ensembl chr 1:231,746,548...231,759,554
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G |
Fn1 |
fibronectin 1 |
multiple interactions |
ISO |
Amygdalin inhibits the reaction [TGFB1 protein results in increased expression of FN1 mRNA]; Amygdalin inhibits the reaction [TGFB1 protein results in increased expression of FN1 protein] |
CTD |
PMID:36457260 |
|
NCBI chr 9:73,196,044...73,264,695
Ensembl chr 9:73,196,044...73,264,678
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G |
Hpse |
heparanase |
multiple interactions |
ISO |
Amygdalin inhibits the reaction [TGFB1 protein results in increased expression of HPSE protein] Amygdalin inhibits the reaction [Ovalbumin results in increased expression of HPSE protein]; Amygdalin inhibits the reaction [TGFB1 protein results in increased expression of HPSE protein] |
CTD |
PMID:36457260 |
|
NCBI chr14:8,896,593...8,937,011
Ensembl chr14:8,896,593...8,937,010
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|
G |
Ptgs1 |
prostaglandin-endoperoxide synthase 1 |
multiple interactions |
ISO |
[peoniflorin co-treated with benzoylpaeoniflorin co-treated with Amygdalin] inhibits the reaction [Lipopolysaccharides results in increased expression of PTGS1 mRNA]; Amygdalin inhibits the reaction [Lipopolysaccharides results in increased expression of PTGS1 mRNA] |
CTD |
PMID:33149750 |
|
NCBI chr 3:19,584,015...19,605,589
Ensembl chr 3:19,584,015...19,605,586
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G |
Ptgs2 |
prostaglandin-endoperoxide synthase 2 |
multiple interactions |
ISO |
[peoniflorin co-treated with benzoylpaeoniflorin co-treated with Amygdalin] inhibits the reaction [Lipopolysaccharides results in increased expression of PTGS2 mRNA]; Amygdalin inhibits the reaction [Lipopolysaccharides results in increased expression of PTGS2 mRNA] |
CTD |
PMID:33149750 |
|
NCBI chr13:62,163,936...62,172,193
Ensembl chr13:62,163,932...62,172,188
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G |
Tgfb1 |
transforming growth factor, beta 1 |
multiple interactions |
ISO |
Amygdalin inhibits the reaction [TGFB1 protein results in increased expression of ACTA2 mRNA]; Amygdalin inhibits the reaction [TGFB1 protein results in increased expression of ACTA2 protein]; Amygdalin inhibits the reaction [TGFB1 protein results in increased expression of FN1 mRNA]; Amygdalin inhibits the reaction [TGFB1 protein results in increased expression of FN1 protein]; Amygdalin inhibits the reaction [TGFB1 protein results in increased expression of HPSE protein]; Amygdalin inhibits the reaction [TGFB1 protein results in increased expression of VIM mRNA]; Amygdalin inhibits the reaction [TGFB1 protein results in increased expression of VIM protein]; Amygdalin inhibits the reaction [TGFB1 protein results in increased secretion of TGFB1 protein] Amygdalin inhibits the reaction [Ovalbumin results in increased secretion of TGFB1 protein]; Amygdalin inhibits the reaction [TGFB1 protein results in increased expression of ACTA2 mRNA]; Amygdalin inhibits the reaction [TGFB1 protein results in increased expression of ACTA2 protein]; Amygdalin inhibits the reaction [TGFB1 protein results in increased expression of FN1 mRNA]; Amygdalin inhibits the reaction [TGFB1 protein results in increased expression of FN1 protein]; Amygdalin inhibits the reaction [TGFB1 protein results in increased expression of HPSE protein]; Amygdalin inhibits the reaction [TGFB1 protein results in increased expression of VIM mRNA]; Amygdalin inhibits the reaction [TGFB1 protein results in increased expression of VIM protein]; Amygdalin inhibits the reaction [TGFB1 protein results in increased secretion of TGFB1 protein] |
CTD |
PMID:36457260 |
|
NCBI chr 1:81,196,532...81,212,848
Ensembl chr 1:81,196,532...81,212,847
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G |
Vim |
vimentin |
multiple interactions |
ISO |
Amygdalin inhibits the reaction [TGFB1 protein results in increased expression of VIM mRNA]; Amygdalin inhibits the reaction [TGFB1 protein results in increased expression of VIM protein] |
CTD |
PMID:36457260 |
|
NCBI chr17:76,668,701...76,677,186
Ensembl chr17:76,668,647...76,677,187
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G |
Aacs |
acetoacetyl-CoA synthetase |
increases expression |
ISO |
Glucosamine results in increased expression of AACS mRNA |
CTD |
PMID:17178593 |
|
NCBI chr12:31,113,098...31,156,411
Ensembl chr12:31,113,098...31,160,954
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G |
Abcg1 |
ATP binding cassette subfamily G member 1 |
increases expression |
EXP |
Glucosamine results in increased expression of ABCG1 mRNA |
CTD |
PMID:17109745 |
|
NCBI chr20:9,126,687...9,182,948
Ensembl chr20:9,126,687...9,182,948
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G |
Acaca |
acetyl-CoA carboxylase alpha |
increases expression |
ISO |
Glucosamine results in increased expression of ACACA mRNA |
CTD |
PMID:22096489 |
|
NCBI chr10:69,014,261...69,276,453
Ensembl chr10:69,014,170...69,276,457
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G |
Acan |
aggrecan |
multiple interactions increases expression decreases expression affects expression |
ISO EXP |
Glucosamine analog affects the reaction [IL1B results in decreased expression of ACAN mRNA]; Glucosamine inhibits the reaction [IL1B protein results in decreased expression of ACAN mRNA]; Glucosamine results in decreased cleavage of and results in decreased secretion of ACAN protein Glucosamine results in increased expression of ACAN mRNA Glucosamine inhibits the reaction [IL1B results in decreased expression of ACAN mRNA] Glucosamine analog results in increased expression of ACAN protein; Glucosamine results in increased expression of ACAN mRNA; Glucosamine results in increased expression of ACAN protein Glucosamine analog results in decreased expression of ACAN mRNA Glucosamine analog affects the expression of ACAN mRNA |
CTD |
PMID:12801482 PMID:16300972 PMID:16872674 PMID:17109745 PMID:17337215 PMID:18321735 PMID:19909832 More...
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|
NCBI chr 1:132,981,582...133,044,416
Ensembl chr 1:132,981,582...133,043,627
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G |
Acot1 |
acyl-CoA thioesterase 1 |
increases expression |
ISO |
Glucosamine results in increased expression of ACOT1 mRNA |
CTD |
PMID:17178593 |
|
NCBI chr 6:103,636,173...103,644,167
Ensembl chr 6:103,636,041...103,644,163
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G |
Acox2 |
acyl-CoA oxidase 2 |
decreases expression |
ISO |
Glucosamine results in decreased expression of ACOX2 mRNA |
CTD |
PMID:17178593 |
|
NCBI chr15:16,660,584...16,692,160
Ensembl chr15:16,660,272...16,692,160
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G |
Acss2 |
acyl-CoA synthetase short-chain family member 2 |
increases expression |
ISO |
Glucosamine results in increased expression of ACSS2 mRNA |
CTD |
PMID:17178593 |
|
NCBI chr 3:144,003,808...144,047,452
Ensembl chr 3:144,004,336...144,059,675
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G |
Adam15 |
ADAM metallopeptidase domain 15 |
multiple interactions decreases expression |
EXP |
Glucosamine affects the reaction [IL1B results in decreased expression of ADAM15 mRNA]; IL1B affects the reaction [Glucosamine results in decreased expression of ADAM15 mRNA] |
CTD |
PMID:17109745 |
|
NCBI chr 2:174,754,629...174,765,136
Ensembl chr 2:174,754,633...174,765,113
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G |
Adam17 |
ADAM metallopeptidase domain 17 |
multiple interactions increases expression |
EXP |
Glucosamine inhibits the reaction [IL1B results in increased expression of ADAM17 mRNA]; IL1B affects the reaction [Glucosamine results in increased expression of ADAM17 mRNA] |
CTD |
PMID:17109745 |
|
NCBI chr 6:40,872,936...40,920,700
Ensembl chr 6:40,872,856...40,920,639
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G |
Adamts1 |
ADAM metallopeptidase with thrombospondin type 1 motif, 1 |
decreases expression multiple interactions |
ISO EXP |
Glucosamine analog results in decreased expression of ADAMTS1 mRNA Glucosamine results in decreased expression of ADAMTS1 mRNA Glucosamine inhibits the reaction [IL1B results in increased expression of ADAMTS1 mRNA]; IL1B inhibits the reaction [Glucosamine results in decreased expression of ADAMTS1 mRNA] |
CTD |
PMID:16300972 PMID:17109745 |
|
NCBI chr11:24,932,227...24,941,068
Ensembl chr11:24,931,761...24,941,103
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G |
Adamts20 |
ADAM metallopeptidase with thrombospondin type 1 motif, 20 |
decreases cleavage |
ISO |
Glucosamine results in decreased cleavage of ADAMTS20 protein alternative form |
CTD |
PMID:19909832 |
|
NCBI chr 7:125,396,227...125,528,020
Ensembl chr 7:125,397,734...125,527,777
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G |
Adamts4 |
ADAM metallopeptidase with thrombospondin type 1 motif, 4 |
increases expression |
EXP |
Glucosamine results in increased expression of ADAMTS4 mRNA |
CTD |
PMID:17109745 |
|
NCBI chr13:83,670,556...83,680,045
Ensembl chr13:83,670,183...83,680,065
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G |
Adamts5 |
ADAM metallopeptidase with thrombospondin type 1 motif, 5 |
decreases expression multiple interactions |
ISO |
Glucosamine analog results in decreased expression of ADAMTS5 mRNA Glucosamine results in decreased cleavage of and results in decreased activity of ADAMTS5 protein alternative form |
CTD |
PMID:16300972 PMID:19909832 |
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NCBI chr11:25,000,627...25,047,205
Ensembl chr11:25,000,637...25,047,205
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Adamts9 |
ADAM metallopeptidase with thrombospondin type 1 motif, 9 |
decreases cleavage |
ISO |
Glucosamine results in decreased cleavage of ADAMTS9 protein alternative form |
CTD |
PMID:19909832 |
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NCBI chr 4:125,290,633...125,462,988
Ensembl chr 4:125,291,490...125,462,929
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G |
Adipoq |
adiponectin, C1Q and collagen domain containing |
increases expression |
ISO EXP |
Glucosamine results in increased expression of ADIPOQ mRNA |
CTD |
PMID:15694357 |
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NCBI chr11:77,721,912...77,735,644
Ensembl chr11:77,721,912...77,735,564
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G |
Afp |
alpha-fetoprotein |
increases expression |
ISO |
Glucosamine results in increased expression of AFP mRNA |
CTD |
PMID:17178593 |
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NCBI chr14:17,573,412...17,591,476
Ensembl chr14:17,573,412...17,591,480
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G |
Agt |
angiotensinogen |
increases expression |
ISO |
Glucosamine results in increased expression of AGT mRNA |
CTD |
PMID:17178593 |
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NCBI chr19:52,529,139...52,549,618
Ensembl chr19:52,529,185...52,540,977
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G |
Ahi1 |
Abelson helper integration site 1 |
decreases expression |
ISO |
Glucosamine results in decreased expression of AHI1 mRNA |
CTD |
PMID:17178593 |
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NCBI chr 1:15,762,485...15,891,213
Ensembl chr 1:15,762,462...15,891,041
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G |
Akt1 |
AKT serine/threonine kinase 1 |
affects phosphorylation multiple interactions |
ISO |
Glucosamine analog affects the phosphorylation of AKT1 protein Glucosamine inhibits the reaction [INS1 protein results in increased phosphorylation of AKT1 protein]; OSTN protein affects the reaction [Glucosamine inhibits the reaction [INS1 protein results in increased phosphorylation of AKT1 protein]] Glucosamine analog affects the reaction [IL1B results in increased phosphorylation of AKT1 protein]; Glucosamine promotes the reaction [IL1B results in increased phosphorylation of AKT1 protein] |
CTD |
PMID:18080321 PMID:18340449 PMID:30602124 |
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NCBI chr 6:131,713,716...131,735,319
Ensembl chr 6:131,713,720...131,733,921
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G |
Alb |
albumin |
multiple interactions |
EXP |
[LEPR protein affects the susceptibility to Glucosamine] which affects the expression of ALB protein |
CTD |
PMID:33345901 |
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NCBI chr14:17,607,397...17,622,814
Ensembl chr14:17,607,381...17,622,836
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G |
Alg12 |
ALG12, alpha-1,6-mannosyltransferase |
decreases expression |
ISO |
Glucosamine results in decreased expression of ALG12 mRNA |
CTD |
PMID:17178593 |
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NCBI chr 7:119,895,112...119,909,488
Ensembl chr 7:119,895,120...119,909,458
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G |
Alpl |
alkaline phosphatase, biomineralization associated |
multiple interactions increases expression increases activity |
ISO |
4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide inhibits the reaction [Glucosamine analog results in increased activity of ALPL protein] Glucosamine analog results in increased expression of ALPL mRNA |
CTD |
PMID:20458730 |
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NCBI chr 5:149,951,397...150,006,424
Ensembl chr 5:149,951,409...150,006,446
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G |
Apoa1 |
apolipoprotein A1 |
increases secretion increases stability |
ISO |
Glucosamine results in increased secretion of APOA1 protein Glucosamine results in increased stability of APOA1 mRNA |
CTD |
PMID:15164326 |
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NCBI chr 8:46,527,251...46,529,035
Ensembl chr 8:46,527,144...46,529,035
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G |
Apob |
apolipoprotein B |
multiple interactions increases degradation increases ubiquitination decreases secretion decreases localization decreases expression |
ISO EXP |
acetylleucyl-leucyl-norleucinal inhibits the reaction [Glucosamine results in decreased expression of and results in decreased secretion of APOB protein]; Glucosamine results in decreased expression of and results in decreased secretion of APOB protein; Oleic Acid inhibits the reaction [Glucosamine results in decreased secretion of APOB protein] Oleic Acid inhibits the reaction [Glucosamine results in increased degradation of APOB protein] Glucosamine results in increased ubiquitination of APOB protein Glucosamine results in decreased localization of APOB protein Glucosamine results in decreased expression of APOB protein |
CTD |
PMID:15618547 PMID:19383982 |
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NCBI chr 6:30,844,386...30,883,983
Ensembl chr 6:30,844,368...30,892,497
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G |
Apoe |
apolipoprotein E |
multiple interactions |
ISO |
[Streptozocin co-treated with APOE mutant form] results in increased abundance of Glucosamine; INS1 inhibits the reaction [[Streptozocin co-treated with APOE mutant form] results in increased abundance of Glucosamine] |
CTD |
PMID:16380481 |
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NCBI chr 1:79,353,924...79,357,852
Ensembl chr 1:79,353,916...79,357,932
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G |
Ass1 |
argininosuccinate synthase 1 |
multiple interactions |
EXP |
Glucosamine inhibits the reaction [IL1B results in increased expression of ASS1 mRNA] |
CTD |
PMID:17109745 |
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NCBI chr 3:14,747,355...14,796,909
Ensembl chr 3:14,747,368...14,796,903
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G |
Atf3 |
activating transcription factor 3 |
decreases expression |
ISO |
Glucosamine results in decreased expression of ATF3 mRNA |
CTD |
PMID:17178593 |
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NCBI chr13:102,751,278...102,800,520
Ensembl chr13:102,751,321...102,764,631
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G |
Atf4 |
activating transcription factor 4 |
multiple interactions increases expression |
ISO |
4-phenylbutyric acid inhibits the reaction [Glucosamine results in increased expression of ATF4 mRNA]; 4-phenylbutyric acid inhibits the reaction [Glucosamine results in increased expression of ATF4 protein]; EIF2AK3 protein affects the reaction [Glucosamine results in increased expression of ATF4 mRNA]; GSK2656157 inhibits the reaction [Glucosamine results in increased expression of ATF4 mRNA] NUS1 protein inhibits the reaction [Glucosamine results in increased expression of ATF4 mRNA] Glucosamine results in increased expression of ATF4 mRNA; Glucosamine results in increased expression of ATF4 protein |
CTD |
PMID:30602124 PMID:33812996 |
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NCBI chr 7:111,804,135...111,806,457
Ensembl chr 7:111,804,183...111,806,446
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G |
Atf6 |
activating transcription factor 6 |
multiple interactions increases expression decreases expression |
ISO EXP |
4-phenylbutyric acid inhibits the reaction [Glucosamine results in increased expression of ATF6 mRNA]; ATF6 mutant form inhibits the reaction [Glucosamine results in decreased expression of MEF2A mRNA]; ATF6 mutant form inhibits the reaction [Glucosamine results in decreased expression of MEF2A protein]; ATF6 mutant form inhibits the reaction [Glucosamine results in decreased expression of PPARGC1A mRNA]; ATF6 mutant form inhibits the reaction [Glucosamine results in decreased expression of PPARGC1A protein]; ATF6 mutant form inhibits the reaction [Glucosamine results in decreased expression of SLC2A4 mRNA]; ATF6 mutant form inhibits the reaction [Glucosamine results in decreased expression of SLC2A4 protein]; NUS1 protein inhibits the reaction [Glucosamine results in increased expression of ATF6 mRNA]; ursodoxicoltaurine inhibits the reaction [Glucosamine results in increased expression of ATF6 mRNA] ATF6 protein affects the reaction [Glucosamine results in increased expression of OSTN mRNA] Glucosamine results in increased expression of ATF6 protein 4-phenylbutyric acid inhibits the reaction [Glucosamine results in increased expression of ATF6 mRNA]; ATF6 mutant form inhibits the reaction [Glucosamine results in decreased expression of MEF2A mRNA]; ATF6 mutant form inhibits the reaction [Glucosamine results in decreased expression of MEF2A protein]; ATF6 mutant form inhibits the reaction [Glucosamine results in decreased expression of PPARGC1A mRNA]; ATF6 mutant form inhibits the reaction [Glucosamine results in decreased expression of PPARGC1A protein]; ATF6 mutant form inhibits the reaction [Glucosamine results in decreased expression of SLC2A4 mRNA]; ATF6 mutant form inhibits the reaction [Glucosamine results in decreased expression of SLC2A4 protein]; ursodoxicoltaurine inhibits the reaction [Glucosamine results in increased expression of ATF6 mRNA] Glucosamine results in decreased expression of ATF6 mRNA |
CTD |
PMID:17178593 PMID:19383982 PMID:20165829 PMID:30602124 PMID:33812996 |
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NCBI chr13:82,927,579...83,106,381
Ensembl chr13:82,930,034...83,107,177
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G |
Atf7ip |
activating transcription factor 7 interacting protein |
increases expression |
ISO |
Glucosamine results in increased expression of ATF7IP mRNA |
CTD |
PMID:17178593 |
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NCBI chr 4:169,385,872...169,471,652
Ensembl chr 4:169,385,872...169,471,650
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G |
Atp2a2 |
ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 2 |
decreases expression |
ISO |
Glucosamine results in decreased expression of ATP2A2 mRNA |
CTD |
PMID:17178593 |
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NCBI chr12:34,072,710...34,122,142
Ensembl chr12:34,072,683...34,122,101
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G |
Azin1 |
antizyme inhibitor 1 |
decreases expression multiple interactions |
EXP |
Glucosamine results in decreased expression of AZIN1 mRNA IL1B promotes the reaction [Glucosamine results in increased expression of AZIN1 mRNA] |
CTD |
PMID:17109745 |
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NCBI chr 7:69,654,773...69,681,578
Ensembl chr 7:69,654,663...69,681,578
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G |
B3gat3 |
beta-1,3-glucuronyltransferase 3 |
multiple interactions increases expression |
EXP |
[XDH protein co-treated with Hypoxanthine] inhibits the reaction [Glucosamine results in increased expression of B3GAT3 mRNA]; Glucosamine inhibits the reaction [IL1B protein results in decreased activity of B3GAT3 protein]; Glucosamine inhibits the reaction [IL1B protein results in decreased expression of B3GAT3 mRNA] |
CTD |
PMID:11229466 PMID:11801247 |
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NCBI chr 1:205,817,374...205,823,928
Ensembl chr 1:205,817,378...205,837,807
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G |
Bcl2l1 |
Bcl2-like 1 |
decreases expression multiple interactions |
ISO |
Glucosamine results in decreased expression of BCL2L1 protein pepstatin inhibits the reaction [Glucosamine results in decreased expression of BCL2L1 protein] |
CTD |
PMID:15972124 PMID:16850161 |
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NCBI chr 3:141,253,508...141,304,582
Ensembl chr 3:141,253,523...141,303,479
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G |
Bdnf |
brain-derived neurotrophic factor |
decreases expression |
ISO |
Glucosamine results in decreased expression of BDNF mRNA |
CTD |
PMID:17178593 |
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NCBI chr 3:96,165,042...96,215,621
Ensembl chr 3:96,165,042...96,215,615
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G |
Bglap |
bone gamma-carboxyglutamate protein |
increases expression |
ISO |
Glucosamine analog results in increased expression of BGLAP mRNA |
CTD |
PMID:20458730 |
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NCBI chr 2:173,838,518...173,839,495
Ensembl chr 2:173,838,518...173,839,495
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G |
Bgn |
biglycan |
multiple interactions decreases expression |
EXP |
Glucosamine inhibits the reaction [IL1B results in increased expression of BGN mRNA]; IL1B affects the reaction [Glucosamine results in decreased expression of BGN mRNA] |
CTD |
PMID:17109745 |
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NCBI chr X:151,197,296...151,209,458
Ensembl chr X:151,197,273...151,209,461
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G |
Bmal1 |
basic helix-loop-helix ARNT like 1 |
decreases expression |
ISO |
Glucosamine results in decreased expression of BMAL1 mRNA; Glucosamine results in decreased expression of BMAL1 protein |
CTD |
PMID:24442997 |
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NCBI chr 1:167,331,756...167,430,235
Ensembl chr 1:167,331,633...167,430,231
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G |
Bmp2 |
bone morphogenetic protein 2 |
multiple interactions |
EXP |
Glucosamine inhibits the reaction [IL1B results in increased expression of BMP2 mRNA] |
CTD |
PMID:17109745 |
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NCBI chr 3:120,812,660...120,822,579
Ensembl chr 3:120,812,882...120,821,397
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G |
Bmp4 |
bone morphogenetic protein 4 |
decreases expression multiple interactions |
EXP |
Glucosamine results in decreased expression of BMP4 mRNA Glucosamine promotes the reaction [IL1B results in decreased expression of BMP4 mRNA] |
CTD |
PMID:17109745 |
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NCBI chr15:19,618,538...19,633,494
Ensembl chr15:19,618,542...19,623,306
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G |
Bmp6 |
bone morphogenetic protein 6 |
multiple interactions decreases expression |
EXP |
Glucosamine inhibits the reaction [IL1B results in increased expression of BMP6 mRNA] Glucosamine results in decreased expression of BMP6 mRNA |
CTD |
PMID:17109745 |
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NCBI chr17:26,318,121...26,469,691
Ensembl chr17:26,318,569...26,470,365
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G |
Bmp7 |
bone morphogenetic protein 7 |
multiple interactions increases expression |
EXP |
Glucosamine inhibits the reaction [IL1B results in increased expression of BMP7 mRNA] Glucosamine results in increased expression of BMP7 mRNA |
CTD |
PMID:17109745 |
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NCBI chr 3:161,639,915...161,716,938
Ensembl chr 3:161,516,462...161,716,788
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G |
Calr |
calreticulin |
decreases expression |
ISO |
Glucosamine results in decreased expression of CALR mRNA |
CTD |
PMID:17178593 |
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NCBI chr19:23,308,525...23,313,420
Ensembl chr19:23,308,351...23,313,414
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G |
Car3 |
carbonic anhydrase 3 |
decreases expression |
EXP |
Glucosamine results in decreased expression of CAR3 mRNA |
CTD |
PMID:17109745 |
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NCBI chr 2:86,770,418...86,780,011
Ensembl chr 2:86,770,420...86,784,280
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G |
Casp3 |
caspase 3 |
increases cleavage multiple interactions |
ISO |
Glucosamine results in increased cleavage of CASP3 protein Glucosamine results in increased activity of and results in increased cleavage of CASP3 protein |
CTD |
PMID:16850161 PMID:22020377 |
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NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648
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G |
Casp4 |
caspase 4 |
decreases expression |
ISO |
Glucosamine results in decreased expression of CASP4 mRNA |
CTD |
PMID:17178593 |
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NCBI chr 8:2,599,017...2,635,097
Ensembl chr 8:2,598,876...2,635,092
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G |
Cbr2 |
carbonyl reductase 2 |
increases expression |
ISO |
Glucosamine results in increased expression of CBR2 mRNA |
CTD |
PMID:17178593 |
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NCBI chr10:106,008,535...106,012,838
Ensembl chr10:105,991,589...106,013,001
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G |
Cbr3 |
carbonyl reductase 3 |
increases expression |
ISO |
Glucosamine results in increased expression of CBR3 mRNA |
CTD |
PMID:17178593 |
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NCBI chr11:33,008,615...33,016,877
Ensembl chr11:33,008,615...33,016,875
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G |
Ccl2 |
C-C motif chemokine ligand 2 |
multiple interactions increases expression |
ISO EXP |
Alloxan inhibits the reaction [Glucosamine inhibits the reaction [Cathelicidins results in increased expression of CCL2 protein]]; Glucosamine analog inhibits the reaction [IL1B results in increased secretion of CCL2 protein]; Glucosamine inhibits the reaction [Cathelicidins results in increased expression of CCL2 mRNA]; Glucosamine inhibits the reaction [Cathelicidins results in increased expression of CCL2 protein]; Glucosamine inhibits the reaction [TNF results in increased expression of CCL2 mRNA]; Glucosamine inhibits the reaction [TNF results in increased expression of CCL2 protein] Glucosamine results in increased expression of CCL2 mRNA Glucosamine inhibits the reaction [IL1B results in increased expression of CCL2 mRNA]; IL1B promotes the reaction [Glucosamine results in increased expression of CCL2 mRNA] |
CTD |
PMID:17109745 PMID:18080321 PMID:18949387 PMID:19020780 |
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NCBI chr10:67,005,424...67,007,222
Ensembl chr10:67,005,424...67,007,226
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G |
Ccl20 |
C-C motif chemokine ligand 20 |
multiple interactions increases expression |
EXP |
Glucosamine inhibits the reaction [IL1B results in increased expression of CCL20 mRNA]; IL1B promotes the reaction [Glucosamine results in increased expression of CCL20 mRNA] |
CTD |
PMID:17109745 |
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NCBI chr 9:84,389,031...84,391,629
Ensembl chr 9:84,388,904...84,391,629
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G |
Ccl22 |
C-C motif chemokine ligand 22 |
multiple interactions |
EXP |
Glucosamine inhibits the reaction [IL1B results in increased expression of CCL22 mRNA] |
CTD |
PMID:17109745 |
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NCBI chr19:10,257,602...10,264,373
Ensembl chr19:10,257,601...10,264,400
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G |
Ccl3 |
C-C motif chemokine ligand 3 |
multiple interactions |
EXP |
Glucosamine inhibits the reaction [IL1B results in increased expression of CCL3 mRNA] |
CTD |
PMID:17109745 |
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NCBI chr10:68,451,388...68,452,938
Ensembl chr10:68,451,388...68,452,938
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G |
Ccl5 |
C-C motif chemokine ligand 5 |
multiple interactions |
ISO EXP |
Glucosamine analog inhibits the reaction [IL1B results in increased secretion of CCL5 protein] Glucosamine inhibits the reaction [IL1B results in increased expression of CCL5 mRNA] |
CTD |
PMID:17109745 PMID:18080321 |
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NCBI chr10:68,322,826...68,327,380
Ensembl chr10:68,322,829...68,327,377
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G |
Ccl7 |
C-C motif chemokine ligand 7 |
multiple interactions increases expression |
EXP |
Glucosamine inhibits the reaction [IL1B results in increased expression of CCL7 mRNA]; IL1B promotes the reaction [Glucosamine results in increased expression of CCL7 mRNA] |
CTD |
PMID:17109745 |
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NCBI chr10:67,016,446...67,018,296
Ensembl chr10:67,016,446...67,018,303
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G |
Ccn2 |
cellular communication network factor 2 |
increases expression |
EXP |
Glucosamine analog results in increased expression of CCN2 mRNA |
CTD |
PMID:21466783 |
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NCBI chr 1:20,802,199...20,805,315
Ensembl chr 1:20,802,199...20,805,734
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G |
Ccnb1 |
cyclin B1 |
decreases expression |
EXP |
Glucosamine results in decreased expression of CCNB1 mRNA |
CTD |
PMID:17109745 |
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NCBI chr 2:31,912,190...31,921,163
Ensembl chr 2:31,912,193...31,921,172
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G |
Cd24 |
CD24 molecule |
increases expression |
ISO |
Glucosamine results in increased expression of CD24A mRNA |
CTD |
PMID:17178593 |
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NCBI chr20:47,074,353...47,079,662
Ensembl chr20:47,073,512...47,079,662
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G |
Cd28 |
Cd28 molecule |
increases expression |
EXP |
Glucosamine results in increased expression of CD28 mRNA |
CTD |
PMID:17109745 |
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NCBI chr 9:62,166,324...62,194,674
Ensembl chr 9:62,166,192...62,194,685
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G |
Cdc20 |
cell division cycle 20 |
decreases expression |
EXP |
Glucosamine results in decreased expression of CDC20 mRNA |
CTD |
PMID:17109745 |
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NCBI chr 5:131,966,203...131,970,406
Ensembl chr 5:131,966,215...131,970,512
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G |
Cdc23 |
cell division cycle 23 |
decreases expression |
EXP |
Glucosamine results in decreased expression of CDC23 mRNA |
CTD |
PMID:17109745 |
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NCBI chr18:26,236,891...26,260,611
Ensembl chr18:26,236,890...26,291,163
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G |
Cdk1 |
cyclin-dependent kinase 1 |
decreases expression |
EXP |
Glucosamine results in decreased expression of CDK1 mRNA |
CTD |
PMID:17109745 |
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NCBI chr20:19,266,226...19,281,417
Ensembl chr20:19,266,248...19,281,408
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G |
Cdkn1a |
cyclin-dependent kinase inhibitor 1A |
increases expression |
EXP ISO |
Glucosamine results in increased expression of CDKN1A protein Glucosamine results in increased expression of CDKN1A mRNA |
CTD |
PMID:15654767 PMID:17178593 |
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NCBI chr20:7,149,177...7,159,727
Ensembl chr20:7,149,217...7,159,585
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G |
Cdkn1b |
cyclin-dependent kinase inhibitor 1B |
decreases expression |
EXP |
Glucosamine results in decreased expression of CDKN1B protein |
CTD |
PMID:15654767 |
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NCBI chr 4:167,760,067...167,765,177
Ensembl chr 4:167,760,181...167,764,982
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G |
Cdkn3 |
cyclin-dependent kinase inhibitor 3 |
decreases expression |
EXP |
Glucosamine results in decreased expression of CDKN3 mRNA |
CTD |
PMID:17109745 |
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NCBI chr15:20,022,522...20,033,948
Ensembl chr15:20,022,664...20,033,945
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G |
Cenpf |
centromere protein F |
decreases expression |
EXP |
Glucosamine results in decreased expression of CENPF mRNA |
CTD |
PMID:17109745 |
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NCBI chr13:101,184,127...101,229,714
Ensembl chr13:101,184,127...101,229,669
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G |
Chi3l1 |
chitinase 3 like 1 |
decreases expression |
ISO |
Glucosamine analog results in decreased expression of CHI3L1 mRNA |
CTD |
PMID:16142878 |
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NCBI chr13:45,641,802...45,649,787
Ensembl chr13:45,641,802...45,649,787
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G |
Chuk |
component of inhibitor of nuclear factor kappa B kinase complex |
multiple interactions decreases activity |
ISO |
Glucosamine analog results in decreased activity of and results in decreased localization of CHUK protein Glucosamine analog results in decreased activity of CHUK protein |
CTD |
PMID:20113495 |
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NCBI chr 1:242,959,539...242,995,066
Ensembl chr 1:242,959,760...242,995,065
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G |
Ckap2 |
cytoskeleton associated protein 2 |
decreases expression |
EXP |
Glucosamine results in decreased expression of CKAP2 mRNA |
CTD |
PMID:17109745 |
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NCBI chr16:69,839,668...69,864,852
Ensembl chr16:69,839,630...69,864,913
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G |
Clock |
clock circadian regulator |
decreases expression |
ISO |
Glucosamine results in decreased expression of CLOCK mRNA; Glucosamine results in decreased expression of CLOCK protein |
CTD |
PMID:24442997 |
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NCBI chr14:31,908,542...31,992,673
Ensembl chr14:31,908,566...31,990,400
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G |
Clta |
clathrin, light chain A |
decreases expression |
EXP |
Glucosamine results in decreased expression of CLTA mRNA |
CTD |
PMID:17109745 |
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NCBI chr 5:58,244,253...58,263,480
Ensembl chr 5:58,245,442...58,263,472
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G |
Col11a1 |
collagen type XI alpha 1 chain |
multiple interactions decreases expression |
EXP |
Glucosamine inhibits the reaction [IL1B results in decreased expression of COL11A1 mRNA]; IL1B affects the reaction [Glucosamine results in decreased expression of COL11A1 mRNA] |
CTD |
PMID:17109745 |
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NCBI chr 2:201,820,715...202,013,853
Ensembl chr 2:201,820,715...202,013,853
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G |
Col1a1 |
collagen type I alpha 1 chain |
multiple interactions decreases expression |
ISO |
Glucosamine inhibits the reaction [IL1B protein results in increased expression of COL1A1 mRNA] Glucosamine results in decreased expression of COL1A1 mRNA |
CTD |
PMID:18321735 |
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NCBI chr10:79,883,622...79,900,625
Ensembl chr10:79,883,622...79,900,624
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G |
Col2a1 |
collagen type II alpha 1 chain |
multiple interactions affects expression increases expression |
ISO EXP |
Glucosamine analog affects the reaction [IL1B results in decreased expression of COL2A1 mRNA]; Glucosamine inhibits the reaction [IL1B protein results in decreased expression of COL2A1 mRNA] Glucosamine inhibits the reaction [IL1B results in decreased expression of COL2A1 mRNA] Glucosamine analog affects the expression of COL2A1 mRNA Glucosamine analog results in increased expression of COL2A1 mRNA; Glucosamine results in increased expression of COL2A1 mRNA |
CTD |
PMID:16300972 PMID:17109745 PMID:17337215 PMID:18321735 |
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NCBI chr 7:129,098,489...129,127,560
Ensembl chr 7:129,098,786...129,127,546
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G |
Col3a1 |
collagen type III alpha 1 chain |
multiple interactions |
EXP |
Glucosamine inhibits the reaction [IL1B results in decreased expression of COL3A1 mRNA] |
CTD |
PMID:17109745 |
|
NCBI chr 9:47,374,611...47,410,547
Ensembl chr 9:47,374,593...47,410,547
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G |
Col8a1 |
collagen type VIII alpha 1 chain |
multiple interactions decreases expression |
EXP |
Glucosamine inhibits the reaction [IL1B results in increased expression of COL8A1 mRNA]; IL1B inhibits the reaction [Glucosamine results in decreased expression of COL8A1 mRNA] |
CTD |
PMID:17109745 |
|
NCBI chr11:42,776,851...42,906,432
Ensembl chr11:42,777,628...42,906,424
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G |
Csf1 |
colony stimulating factor 1 |
multiple interactions decreases expression |
EXP |
Glucosamine inhibits the reaction [IL1B results in increased expression of CSF1 mRNA]; IL1B inhibits the reaction [Glucosamine results in decreased expression of CSF1 mRNA] |
CTD |
PMID:17109745 |
|
NCBI chr 2:195,377,215...195,396,608
Ensembl chr 2:195,377,215...195,411,704
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G |
Csf2 |
colony stimulating factor 2 |
multiple interactions increases expression |
EXP |
Glucosamine inhibits the reaction [IL1B results in increased expression of CSF2 mRNA] Glucosamine results in increased expression of CSF2 mRNA |
CTD |
PMID:17109745 |
|
NCBI chr10:38,386,945...38,388,926
Ensembl chr10:38,386,945...38,389,199
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G |
Csf3 |
colony stimulating factor 3 |
multiple interactions increases expression |
EXP |
Glucosamine inhibits the reaction [IL1B results in increased expression of CSF3 mRNA] Glucosamine results in increased expression of CSF3 mRNA |
CTD |
PMID:17109745 |
|
NCBI chr10:83,660,787...83,664,569
Ensembl chr10:83,661,207...83,663,603
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G |
Ctsd |
cathepsin D |
affects localization multiple interactions increases activity decreases expression |
ISO |
Glucosamine affects the localization of CTSD protein pepstatin inhibits the reaction [Glucosamine results in decreased expression of CTSD protein alternative form] Glucosamine results in increased activity of CTSD protein |
CTD |
PMID:15972124 PMID:16850161 |
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NCBI chr 1:197,527,467...197,539,343
Ensembl chr 1:197,527,467...197,539,488
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G |
Cul2 |
cullin 2 |
multiple interactions |
ISO |
Glucosamine analog inhibits the reaction [TNF results in increased expression of CUL2 mRNA]; Glucosamine inhibits the reaction [TNF results in increased expression of CUL2 mRNA] |
CTD |
PMID:18173918 |
|
NCBI chr17:54,169,093...54,210,197
Ensembl chr17:54,169,086...54,209,968
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G |
Cxcl1 |
C-X-C motif chemokine ligand 1 |
multiple interactions decreases expression |
EXP |
Glucosamine inhibits the reaction [IL1B results in increased expression of CXCL1 mRNA]; IL1B inhibits the reaction [Glucosamine results in decreased expression of CXCL1 mRNA] |
CTD |
PMID:17109745 |
|
NCBI chr14:17,193,364...17,195,143
Ensembl chr14:17,193,365...17,195,215
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G |
Cxcl10 |
C-X-C motif chemokine ligand 10 |
multiple interactions |
ISO EXP |
Glucosamine inhibits the reaction [Lipopolysaccharides results in increased expression of CXCL10 mRNA] Glucosamine inhibits the reaction [IL1B results in increased expression of CXCL10 mRNA] |
CTD |
PMID:17109745 PMID:20737476 |
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NCBI chr14:15,704,772...15,706,969
Ensembl chr14:15,704,758...15,706,975
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G |
Cxcl11 |
C-X-C motif chemokine ligand 11 |
multiple interactions |
EXP |
Glucosamine inhibits the reaction [IL1B results in increased expression of CXCL11 mRNA] |
CTD |
PMID:17109745 |
|
NCBI chr14:15,689,432...15,692,207
Ensembl chr14:15,689,424...15,692,271
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G |
Cxcl12 |
C-X-C motif chemokine ligand 12 |
multiple interactions decreases expression |
EXP |
Glucosamine promotes the reaction [IL1B results in decreased expression of CXCL12 mRNA]; IL1B affects the reaction [Glucosamine results in decreased expression of CXCL12 mRNA] |
CTD |
PMID:17109745 |
|
NCBI chr 4:150,388,326...150,401,173
Ensembl chr 4:150,388,325...150,401,168
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G |
Cxcl2 |
C-X-C motif chemokine ligand 2 |
multiple interactions increases expression |
EXP |
Glucosamine inhibits the reaction [IL1B results in increased expression of CXCL2 mRNA]; IL1B promotes the reaction [Glucosamine results in increased expression of CXCL2 mRNA] |
CTD |
PMID:17109745 |
|
NCBI chr14:17,181,030...17,183,075
Ensembl chr14:17,181,062...17,183,075
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G |
Cxcl3 |
C-X-C motif chemokine ligand 3 |
multiple interactions increases expression |
EXP |
Glucosamine inhibits the reaction [IL1B results in increased expression of CXCL3 mRNA]; IL1B promotes the reaction [Glucosamine results in increased expression of CXCL3 mRNA] |
CTD |
PMID:17109745 |
|
NCBI chr14:17,287,727...17,289,451
Ensembl chr14:17,270,146...17,289,511
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G |
Cxcl6 |
C-X-C motif chemokine ligand 6 |
multiple interactions |
EXP |
Glucosamine inhibits the reaction [IL1B results in increased expression of CXCL5 mRNA] |
CTD |
PMID:17109745 |
|
NCBI chr14:17,310,790...17,312,250
Ensembl chr14:17,310,426...17,313,093
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G |
Cyba |
cytochrome b-245 alpha chain |
decreases expression |
ISO |
Glucosamine results in decreased expression of CYBA mRNA |
CTD |
PMID:18077487 |
|
NCBI chr19:50,487,598...50,495,669
Ensembl chr19:50,487,597...50,495,721
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G |
Cycs |
cytochrome c, somatic |
affects localization |
ISO |
Glucosamine affects the localization of CYCS protein |
CTD |
PMID:15972124 PMID:22020377 |
|
NCBI chr 4:79,651,894...79,653,994
Ensembl chr 4:79,651,378...79,654,054 Ensembl chr18:79,651,378...79,654,054
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G |
Cyp51 |
cytochrome P450, family 51 |
increases expression |
ISO |
Glucosamine results in increased expression of CYP51 mRNA |
CTD |
PMID:17178593 |
|
NCBI chr 4:30,036,956...30,055,410
Ensembl chr 4:30,036,865...30,055,410
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G |
Dbi |
diazepam binding inhibitor |
increases expression |
ISO |
Glucosamine results in increased expression of DBI mRNA |
CTD |
PMID:17178593 |
|
NCBI chr13:31,241,466...31,249,853
Ensembl chr13:31,206,988...31,268,693
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G |
Ddit3 |
DNA-damage inducible transcript 3 |
increases expression multiple interactions decreases expression |
ISO |
Glucosamine results in increased expression of DDIT3 mRNA; Glucosamine results in increased expression of DDIT3 protein NUS1 protein inhibits the reaction [Glucosamine results in increased expression of DDIT3 mRNA] 4-phenylbutyric acid inhibits the reaction [Glucosamine results in increased expression of DDIT3 mRNA]; 4-phenylbutyric acid inhibits the reaction [Glucosamine results in increased expression of DDIT3 protein] Glucosamine results in decreased expression of DDIT3 mRNA |
CTD |
PMID:16380481 PMID:17178593 PMID:30602124 PMID:33812996 |
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NCBI chr 7:63,115,645...63,121,203
Ensembl chr 7:63,116,380...63,121,201
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G |
Ddit4l |
DNA-damage-inducible transcript 4-like |
increases expression |
EXP |
Glucosamine results in increased expression of DDIT4L mRNA |
CTD |
PMID:17109745 |
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NCBI chr 2:226,128,273...226,131,044
Ensembl chr 2:226,128,276...226,131,375
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G |
Dhcr7 |
7-dehydrocholesterol reductase |
increases expression |
ISO |
Glucosamine results in increased expression of DHCR7 mRNA |
CTD |
PMID:17178593 |
|
NCBI chr 1:199,015,081...199,031,055
Ensembl chr 1:199,015,081...199,031,055
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G |
Dnajb11 |
DnaJ heat shock protein family (Hsp40) member B11 |
decreases expression |
ISO |
Glucosamine results in decreased expression of DNAJB11 mRNA |
CTD |
PMID:17178593 |
|
NCBI chr11:78,151,750...78,168,259
Ensembl chr11:78,150,429...78,180,407
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G |
Dnajb9 |
DnaJ heat shock protein family (Hsp40) member B9 |
decreases expression |
ISO |
Glucosamine results in decreased expression of DNAJB9 mRNA |
CTD |
PMID:17178593 |
|
NCBI chr 6:61,270,385...61,276,795
Ensembl chr 6:61,269,913...61,275,063
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G |
Dnajc3 |
DnaJ heat shock protein family (Hsp40) member C3 |
decreases expression |
ISO |
Glucosamine results in decreased expression of DNAJC3 mRNA |
CTD |
PMID:17178593 |
|
NCBI chr15:96,025,605...96,068,585
Ensembl chr15:96,025,624...96,065,181
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G |
Dspp |
dentin sialophosphoprotein |
decreases expression |
ISO |
Glucosamine analog results in decreased expression of DSPP mRNA |
CTD |
PMID:20458730 |
|
NCBI chr14:5,565,562...5,571,669
Ensembl chr14:5,565,629...5,571,672
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G |
Dusp5 |
dual specificity phosphatase 5 |
multiple interactions increases expression |
EXP |
Glucosamine inhibits the reaction [IL1B results in increased expression of DUSP5 mRNA] Glucosamine results in increased expression of DUSP5 mRNA |
CTD |
PMID:17109745 |
|
NCBI chr 1:252,538,408...252,555,320
Ensembl chr 1:252,538,449...252,551,818
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G |
Dusp7 |
dual specificity phosphatase 7 |
multiple interactions decreases expression |
EXP |
Glucosamine inhibits the reaction [IL1B results in increased expression of DUSP7 mRNA]; IL1B affects the reaction [Glucosamine results in decreased expression of DUSP7 mRNA] |
CTD |
PMID:17109745 |
|
NCBI chr 8:107,009,369...107,016,404
Ensembl chr 8:107,008,528...107,016,404
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G |
Dync1i1 |
dynein cytoplasmic 1 intermediate chain 1 |
decreases expression |
EXP |
Glucosamine results in decreased expression of DYNC1I1 mRNA |
CTD |
PMID:17109745 |
|
NCBI chr 4:33,852,597...34,166,159
Ensembl chr 4:33,852,927...34,166,149
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G |
Edem1 |
ER degradation enhancing alpha-mannosidase like protein 1 |
decreases expression |
ISO |
Glucosamine results in decreased expression of EDEM1 mRNA |
CTD |
PMID:17178593 |
|
NCBI chr 4:141,797,631...141,829,717
Ensembl chr 4:141,797,701...141,829,717
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G |
Eif2ak3 |
eukaryotic translation initiation factor 2 alpha kinase 3 |
multiple interactions increases expression increases phosphorylation |
EXP ISO |
EIF2AK3 gene mutant form inhibits the reaction [Glucosamine results in increased phosphorylation of EIF2S1 protein] Glucosamine results in increased expression of EIF2AK3 protein NUS1 protein inhibits the reaction [Glucosamine results in increased expression of EIF2AK3 protein] EIF2AK3 protein affects the reaction [Glucosamine results in increased expression of ATF4 mRNA]; EIF2AK3 protein affects the reaction [Glucosamine results in increased expression of OSTN mRNA]; EIF2AK3 protein affects the reaction [Glucosamine results in increased phosphorylation of EIF2S1 protein] Glucosamine results in increased phosphorylation of EIF2AK3 protein |
CTD |
PMID:16324875 PMID:19383982 PMID:30602124 PMID:33812996 |
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NCBI chr 4:102,805,495...102,866,914
Ensembl chr 4:102,805,510...102,866,911
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G |
Eif2s1 |
eukaryotic translation initiation factor 2 subunit alpha |
increases phosphorylation multiple interactions |
ISO EXP |
Glucosamine results in increased phosphorylation of EIF2S1 protein NUS1 protein inhibits the reaction [Glucosamine results in increased phosphorylation of EIF2S1 protein] 4-phenylbutyric acid inhibits the reaction [Glucosamine results in increased phosphorylation of EIF2S1 protein]; EIF2AK3 protein affects the reaction [Glucosamine results in increased phosphorylation of EIF2S1 protein]; GSK2656157 inhibits the reaction [Glucosamine results in increased phosphorylation of EIF2S1 protein] EIF2AK3 gene mutant form inhibits the reaction [Glucosamine results in increased phosphorylation of EIF2S1 protein] |
CTD |
PMID:16324875 PMID:19383982 PMID:30602124 PMID:33812996 |
|
NCBI chr 6:97,672,829...97,697,499
Ensembl chr 6:97,672,766...97,706,225
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G |
Elovl6 |
ELOVL fatty acid elongase 6 |
increases expression |
ISO |
Glucosamine results in increased expression of ELOVL6 mRNA |
CTD |
PMID:17178593 |
|
NCBI chr 2:218,063,682...218,174,767
Ensembl chr 2:218,063,804...218,171,186
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G |
Epas1 |
endothelial PAS domain protein 1 |
decreases expression multiple interactions |
EXP |
Glucosamine results in decreased expression of EPAS1 mRNA Glucosamine inhibits the reaction [IL1B results in increased expression of EPAS1 mRNA]; IL1B affects the reaction [Glucosamine results in decreased expression of EPAS1 mRNA] |
CTD |
PMID:17109745 |
|
NCBI chr 6:7,790,236...7,871,717
Ensembl chr 6:7,790,647...7,871,228
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G |
Eprs1 |
glutamyl-prolyl-tRNA synthetase 1 |
decreases expression |
ISO |
Glucosamine results in decreased expression of EPRS1 mRNA |
CTD |
PMID:17178593 |
|
NCBI chr13:96,901,548...96,971,966
Ensembl chr13:96,901,575...96,971,966
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G |
Ern1 |
endoplasmic reticulum to nucleus signaling 1 |
multiple interactions increases expression |
ISO |
ERN1 protein affects the reaction [Glucosamine results in increased expression of OSTN mRNA]; ERN1 protein affects the reaction [Glucosamine results in increased splicing of XBP1 mRNA] NUS1 protein inhibits the reaction [Glucosamine results in increased expression of ERN1 mRNA] |
CTD |
PMID:30602124 PMID:33812996 |
|
NCBI chr10:91,326,889...91,421,201
Ensembl chr10:91,330,654...91,421,029
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G |
Fabp4 |
fatty acid binding protein 4 |
increases expression |
ISO EXP |
Glucosamine results in increased expression of FABP4 mRNA |
CTD |
PMID:15694357 |
|
NCBI chr 2:91,580,879...91,585,567
Ensembl chr 2:91,580,885...91,585,578
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G |
Fasn |
fatty acid synthase |
increases expression |
ISO |
Glucosamine results in increased expression of FASN mRNA |
CTD |
PMID:22096489 |
|
NCBI chr10:106,072,093...106,090,259
Ensembl chr10:106,072,091...106,090,261
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G |
Fbp2 |
fructose-bisphosphatase 2 |
increases expression |
ISO |
Glucosamine results in increased expression of FBP2 mRNA |
CTD |
PMID:17178593 |
|
NCBI chr17:2,236,088...2,253,702
Ensembl chr17:2,236,336...2,253,698
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G |
Fgf2 |
fibroblast growth factor 2 |
multiple interactions |
EXP |
Glucosamine promotes the reaction [Glucose results in increased expression of FGF2 mRNA] |
CTD |
PMID:1518840 |
|
NCBI chr 2:120,236,328...120,290,673
Ensembl chr 2:120,236,328...120,291,221
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G |
Fgf7 |
fibroblast growth factor 7 |
decreases expression multiple interactions |
EXP |
Glucosamine results in decreased expression of FGF7 mRNA IL1B inhibits the reaction [Glucosamine results in decreased expression of FGF7 mRNA] |
CTD |
PMID:17109745 |
|
NCBI chr 3:113,280,448...113,333,279
Ensembl chr 3:113,281,283...113,332,929
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G |
Fgf9 |
fibroblast growth factor 9 |
multiple interactions increases expression |
EXP |
Glucosamine inhibits the reaction [IL1B results in increased expression of FGF9 mRNA] Glucosamine results in increased expression of FGF9 mRNA |
CTD |
PMID:17109745 |
|
NCBI chr15:32,208,993...32,254,952
Ensembl chr15:32,210,074...32,253,309
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G |
Fgfr1 |
Fibroblast growth factor receptor 1 |
multiple interactions increases expression |
EXP |
Glucosamine inhibits the reaction [IL1B results in decreased expression of FGFR1 mRNA] Glucosamine results in increased expression of FGFR1 mRNA |
CTD |
PMID:17109745 |
|
NCBI chr16:66,491,930...66,547,161
Ensembl chr16:66,494,042...66,547,350
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G |
Fkbp11 |
FKBP prolyl isomerase 11 |
decreases expression |
ISO |
Glucosamine results in decreased expression of FKBP11 mRNA |
CTD |
PMID:17178593 |
|
NCBI chr 7:129,871,870...129,877,760
Ensembl chr 7:129,871,870...129,875,303
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G |
Fn1 |
fibronectin 1 |
decreases expression |
ISO EXP |
Glucosamine results in decreased expression of FN1 protein |
CTD |
PMID:17178593 |
|
NCBI chr 9:73,196,044...73,264,695
Ensembl chr 9:73,196,044...73,264,678
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G |
Fos |
Fos proto-oncogene, AP-1 transcription factor subunit |
multiple interactions |
ISO |
Glucosamine analog inhibits the reaction [Buthionine Sulfoximine results in increased expression of FOS mRNA] Glucosamine analog inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of FOS protein] |
CTD |
PMID:19375915 PMID:21825963 |
|
NCBI chr 6:105,121,170...105,124,036
Ensembl chr 6:105,121,170...105,124,036
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G |
Furin |
furin (paired basic amino acid cleaving enzyme) |
decreases cleavage multiple interactions |
ISO |
Glucosamine results in decreased cleavage of FURIN protein alternative form Glucosamine results in decreased glycosylation of and results in decreased activity of FURIN protein |
CTD |
PMID:19909832 |
|
NCBI chr 1:134,348,142...134,361,182
Ensembl chr 1:134,348,144...134,364,314
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G |
Fxyd2 |
FXYD domain-containing ion transport regulator 2 |
increases expression |
EXP |
Glucosamine results in increased expression of FXYD2 mRNA |
CTD |
PMID:17109745 |
|
NCBI chr 8:45,712,901...45,720,032
Ensembl chr 8:45,712,903...45,720,203
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G |
Gatm |
glycine amidinotransferase |
decreases expression |
EXP |
Glucosamine results in decreased expression of GATM mRNA |
CTD |
PMID:17109745 |
|
NCBI chr 3:109,658,919...109,675,508
Ensembl chr 3:109,658,951...109,684,129
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G |
Gck |
glucokinase |
decreases expression |
EXP |
Glucosamine results in decreased expression of GCK mRNA |
CTD |
PMID:11893929 |
|
NCBI chr14:80,785,060...80,829,842
Ensembl chr14:80,785,060...80,826,995
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G |
Gclc |
glutamate-cysteine ligase, catalytic subunit |
increases expression |
ISO |
Glucosamine analog results in increased expression of GCLC mRNA |
CTD |
PMID:21825963 |
|
NCBI chr 8:78,629,899...78,668,547
Ensembl chr 8:78,630,127...78,668,544
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G |
Gfpt1 |
glutamine fructose-6-phosphate transaminase 1 |
multiple interactions |
EXP |
[Glucosamine co-treated with INS1 protein] affects the localization of GFPT1 protein |
CTD |
PMID:9453242 |
|
NCBI chr 4:119,496,691...119,546,472
Ensembl chr 4:119,496,714...119,546,471
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G |
Glrx |
glutaredoxin |
increases expression |
ISO |
Glucosamine results in increased expression of GLRX mRNA |
CTD |
PMID:17178593 |
|
NCBI chr 2:5,341,873...5,351,686
Ensembl chr 2:5,341,885...5,351,680
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G |
Gnpnat1 |
glucosamine-phosphate N-acetyltransferase 1 |
decreases expression |
ISO |
Glucosamine results in decreased expression of GNPNAT1 mRNA |
CTD |
PMID:17178593 |
|
NCBI chr15:18,596,180...18,608,854
Ensembl chr15:18,596,442...18,608,739
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G |
Gnptab |
N-acetylglucosamine-1-phosphate transferase subunits alpha and beta |
increases expression |
ISO |
Glucosamine results in increased expression of GNPTAB mRNA |
CTD |
PMID:17178593 |
|
NCBI chr 7:22,800,502...22,866,336
Ensembl chr 7:22,800,485...22,866,933
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|
G |
Gpd1l |
glycerol-3-phosphate dehydrogenase 1 like |
increases expression |
ISO |
Glucosamine results in increased expression of GPD1L mRNA |
CTD |
PMID:17178593 |
|
NCBI chr 8:114,591,103...114,620,771
Ensembl chr 8:114,588,487...114,620,723
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G |
Grem1 |
gremlin 1, DAN family BMP antagonist |
multiple interactions decreases expression |
EXP |
Glucosamine inhibits the reaction [IL1B results in increased expression of GREM1 mRNA]; IL1B inhibits the reaction [Glucosamine results in decreased expression of GREM1 mRNA] |
CTD |
PMID:17109745 |
|
NCBI chr 3:100,512,317...100,524,001
Ensembl chr 3:100,512,313...100,524,082
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|
G |
Gsk3b |
glycogen synthase kinase 3 beta |
multiple interactions decreases phosphorylation |
ISO |
Glucosamine inhibits the reaction [INS protein results in increased phosphorylation of GSK3B protein]; NUS1 protein inhibits the reaction [Glucosamine inhibits the reaction [INS protein results in increased phosphorylation of GSK3B protein]]; PRKAA1 protein promotes the reaction [Glucosamine inhibits the reaction [INS protein results in increased phosphorylation of GSK3B protein]]; PRKAA1 protein promotes the reaction [NUS1 protein inhibits the reaction [Glucosamine inhibits the reaction [INS protein results in increased phosphorylation of GSK3B protein]]] Glucosamine results in decreased phosphorylation of GSK3B protein |
CTD |
PMID:33812996 |
|
NCBI chr11:62,498,997...62,648,665
Ensembl chr11:62,504,316...62,648,646
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|
G |
Gspt1 |
G1 to S phase transition 1 |
multiple interactions |
ISO |
Glucosamine analog inhibits the reaction [TNF results in increased expression of GSPT1 mRNA]; Glucosamine inhibits the reaction [TNF results in increased expression of GSPT1 mRNA] |
CTD |
PMID:18173918 |
|
NCBI chr10:4,362,528...4,397,215
Ensembl chr10:4,362,510...4,397,198
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|
G |
Gstt1 |
glutathione S-transferase theta 1 |
increases expression |
ISO |
Glucosamine results in increased expression of GSTT1 mRNA |
CTD |
PMID:17178593 |
|
NCBI chr20:12,856,613...12,873,586
Ensembl chr20:12,856,669...12,873,585
|
|
G |
Hapln1 |
hyaluronan and proteoglycan link protein 1 |
decreases expression multiple interactions |
EXP |
Glucosamine results in decreased expression of HAPLN1 mRNA Glucosamine inhibits the reaction [IL1B results in decreased expression of HAPLN1 mRNA]; IL1B promotes the reaction [Glucosamine results in decreased expression of HAPLN1 mRNA] |
CTD |
PMID:17109745 |
|
NCBI chr 2:20,631,640...20,696,388
Ensembl chr 2:20,631,640...20,693,777
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|
G |
Herpud1 |
homocysteine inducible ER protein with ubiquitin like domain 1 |
decreases expression |
ISO |
Glucosamine results in decreased expression of HERPUD1 mRNA |
CTD |
PMID:17178593 |
|
NCBI chr19:10,598,411...10,609,002
Ensembl chr19:10,598,417...10,618,424
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|
G |
Hif1a |
hypoxia inducible factor 1 subunit alpha |
multiple interactions decreases expression |
ISO |
Glucosamine affects the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of HIF1A protein]; Glucosamine inhibits the reaction [Oxygen deficiency results in increased expression of HIF1A protein] Glucosamine results in decreased expression of HIF1A mRNA; Glucosamine results in decreased expression of HIF1A protein |
CTD |
PMID:19254699 PMID:22020377 |
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NCBI chr 6:92,624,059...92,669,262
Ensembl chr 6:92,624,390...92,669,261
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G |
Hk1 |
hexokinase 1 |
increases expression |
ISO EXP |
Glucosamine results in increased expression of HK1 mRNA |
CTD |
PMID:11893929 PMID:17178593 |
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NCBI chr20:30,230,488...30,332,099
Ensembl chr20:30,230,486...30,332,131
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G |
Hmga1 |
high mobility group AT-hook 1 |
increases expression |
EXP |
Glucosamine results in increased expression of HMGA1 mRNA |
CTD |
PMID:17109745 |
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NCBI chr20:5,611,088...5,618,755
Ensembl chr20:5,611,694...5,618,752
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G |
Hmgcs1 |
3-hydroxy-3-methylglutaryl-CoA synthase 1 |
increases expression |
ISO |
Glucosamine results in increased expression of HMGCS1 mRNA |
CTD |
PMID:17178593 |
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NCBI chr 2:51,649,368...51,667,100
Ensembl chr 2:51,649,497...51,667,100
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G |
Hmmr |
hyaluronan-mediated motility receptor |
decreases expression |
EXP |
Glucosamine results in decreased expression of HMMR mRNA |
CTD |
PMID:17109745 |
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NCBI chr10:25,132,933...25,163,029
Ensembl chr10:25,132,977...25,163,060
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G |
Hmox1 |
heme oxygenase 1 |
multiple interactions increases expression |
ISO |
Glucosamine inhibits the reaction [IL1B results in decreased expression of HMOX1 mRNA]; Glucosamine inhibits the reaction [IL1B results in decreased expression of HMOX1 protein] Glucosamine results in increased expression of HMOX1 mRNA; Glucosamine results in increased expression of HMOX1 protein |
CTD |
PMID:18077487 |
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NCBI chr19:13,466,287...13,474,082
Ensembl chr19:13,467,244...13,474,079
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G |
Hoxa1 |
homeobox A1 |
decreases expression |
ISO |
Glucosamine results in decreased expression of HOXA1 mRNA |
CTD |
PMID:17178593 |
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NCBI chr 4:81,255,814...81,258,587
Ensembl chr 4:81,255,883...81,258,504
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G |
Hpgd |
15-hydroxyprostaglandin dehydrogenase |
decreases expression |
EXP |
Glucosamine results in decreased expression of HPGD mRNA |
CTD |
PMID:17109745 |
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NCBI chr16:33,986,265...34,024,228
Ensembl chr16:33,986,266...34,024,228
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G |
Hsp90b1 |
heat shock protein 90 beta family member 1 |
decreases expression increases expression |
ISO EXP |
Glucosamine results in decreased expression of HSP90B1 mRNA Glucosamine results in increased expression of HSP90B1 protein |
CTD |
PMID:15618547 PMID:17109745 PMID:17178593 |
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NCBI chr 7:21,110,431...21,124,762
Ensembl chr 7:21,110,457...21,124,788
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G |
Hspa5 |
heat shock protein family A (Hsp70) member 5 |
multiple interactions increases expression decreases expression |
ISO EXP |
4-phenylbutyric acid inhibits the reaction [Glucosamine results in increased expression of HSPA5 mRNA]; NUS1 protein inhibits the reaction [Glucosamine results in increased expression of HSPA5 mRNA]; NUS1 protein inhibits the reaction [Glucosamine results in increased expression of HSPA5 protein]; ursodoxicoltaurine inhibits the reaction [Glucosamine results in increased expression of HSPA5 mRNA] Glucosamine results in increased expression of HSPA5 mRNA; Glucosamine results in increased expression of HSPA5 protein 4-phenylbutyric acid inhibits the reaction [Glucosamine results in increased expression of HSPA5 mRNA]; 4-phenylbutyric acid inhibits the reaction [Glucosamine results in increased expression of HSPA5 protein] 4-phenylbutyric acid inhibits the reaction [Glucosamine results in increased expression of HSPA5 mRNA]; ursodoxicoltaurine inhibits the reaction [Glucosamine results in increased expression of HSPA5 mRNA] Glucosamine results in decreased expression of HSPA5 mRNA |
CTD |
PMID:15618547 PMID:16380481 PMID:17178593 PMID:19383982 PMID:20165829 PMID:22020377 PMID:30602124 PMID:33812996 More...
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NCBI chr 3:18,055,507...18,059,969
Ensembl chr 3:18,055,405...18,059,891
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G |
Hyou1 |
hypoxia up-regulated 1 |
decreases expression |
ISO |
Glucosamine results in decreased expression of HYOU1 mRNA |
CTD |
PMID:17178593 |
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NCBI chr 8:44,706,073...44,718,189
Ensembl chr 8:44,706,263...44,718,186
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G |
Icam1 |
intercellular adhesion molecule 1 |
multiple interactions decreases activity |
ISO EXP |
Alloxan inhibits the reaction [Glucosamine inhibits the reaction [Cathelicidins results in increased expression of ICAM1 protein]]; Glucosamine inhibits the reaction [[IL6 co-treated with TNF] results in increased expression of ICAM1 protein]; Glucosamine inhibits the reaction [Cathelicidins results in increased expression of ICAM1 mRNA]; Glucosamine inhibits the reaction [Cathelicidins results in increased expression of ICAM1 protein]; Glucosamine inhibits the reaction [IFNG promotes the reaction [TNF results in increased expression of ICAM1 protein]]; Glucosamine inhibits the reaction [IFNG results in increased expression of ICAM1 mRNA]; Glucosamine inhibits the reaction [IFNG results in increased expression of ICAM1 protein]; Glucosamine inhibits the reaction [IL1B promotes the reaction [TNF results in increased expression of ICAM1 protein]]; Glucosamine inhibits the reaction [IL1B results in increased expression of ICAM1 mRNA]; Glucosamine inhibits the reaction [IL1B results in increased expression of ICAM1 protein]; Glucosamine inhibits the reaction [IL6 results in increased expression of ICAM1 protein]; Glucosamine inhibits the reaction [TNF promotes the reaction [IFNG results in increased expression of ICAM1 protein]]; Glucosamine inhibits the reaction [TNF promotes the reaction [IL1B results in increased expression of ICAM1 protein]]; Glucosamine inhibits the reaction [TNF results in increased expression of ICAM1 mRNA]; Glucosamine inhibits the reaction [TNF results in increased expression of ICAM1 protein] Glucosamine results in decreased activity of ICAM1 protein Glucosamine inhibits the reaction [Lipopolysaccharides results in increased expression of ICAM1 protein] |
CTD |
PMID:16431966 PMID:16822504 PMID:17238806 PMID:18949387 PMID:19020780 PMID:19098112 More...
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NCBI chr 8:19,553,063...19,565,438
Ensembl chr 8:19,553,645...19,565,438
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G |
Id1 |
inhibitor of DNA binding 1 |
increases expression |
ISO |
Glucosamine results in increased expression of ID1 mRNA |
CTD |
PMID:17178593 |
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NCBI chr 3:141,210,666...141,212,420
Ensembl chr 3:141,211,267...141,212,419
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G |
Id2 |
inhibitor of DNA binding 2 |
increases expression |
ISO |
Glucosamine results in increased expression of ID2 mRNA |
CTD |
PMID:17178593 |
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NCBI chr 6:41,740,556...41,742,393
Ensembl chr 6:41,728,946...41,744,400
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G |
Id3 |
inhibitor of DNA binding 3 |
increases expression |
ISO |
Glucosamine results in increased expression of ID3 mRNA |
CTD |
PMID:17178593 |
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NCBI chr 5:148,372,784...148,374,353
Ensembl chr 5:148,372,762...148,374,349
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G |
Idh1 |
isocitrate dehydrogenase (NADP(+)) 1 |
increases expression |
ISO |
Glucosamine results in increased expression of IDH1 mRNA |
CTD |
PMID:17178593 |
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NCBI chr 9:66,534,146...66,563,703
Ensembl chr 9:66,534,146...66,563,708
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G |
Ifit3 |
interferon-induced protein with tetratricopeptide repeats 3 |
increases expression |
ISO |
Glucosamine results in increased expression of IFIT3 mRNA |
CTD |
PMID:17178593 |
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NCBI chr 1:232,114,166...232,119,311
Ensembl chr 1:232,114,166...232,119,307
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G |
Ifng |
interferon gamma |
decreases secretion multiple interactions |
ISO |
Glucosamine results in decreased secretion of IFNG protein Glucosamine inhibits the reaction [IFNG promotes the reaction [TNF results in increased expression of ICAM1 protein]]; Glucosamine inhibits the reaction [IFNG results in increased expression of ICAM1 mRNA]; Glucosamine inhibits the reaction [IFNG results in increased expression of ICAM1 protein]; Glucosamine inhibits the reaction [IFNG results in increased localization of STAT1 protein modified form]; Glucosamine inhibits the reaction [IFNG results in increased phosphorylation of and results in increased localization of STAT1 protein]; Glucosamine inhibits the reaction [TNF promotes the reaction [IFNG results in increased expression of ICAM1 protein]] |
CTD |
PMID:14507305 PMID:16431966 PMID:16822504 PMID:17238806 |
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NCBI chr 7:53,903,339...53,907,375
Ensembl chr 7:53,903,337...53,907,375
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G |
Igfbp3 |
insulin-like growth factor binding protein 3 |
multiple interactions decreases expression |
EXP |
Glucosamine inhibits the reaction [IL1B results in increased expression of IGFBP3 mRNA]; IL1B inhibits the reaction [Glucosamine results in increased expression of IGFBP3 mRNA] Glucosamine results in decreased expression of IGFBP3 mRNA |
CTD |
PMID:17109745 |
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NCBI chr14:82,056,347...82,064,083
Ensembl chr14:82,056,347...82,064,083
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G |
Igfbp4 |
insulin-like growth factor binding protein 4 |
decreases expression |
ISO |
Glucosamine results in decreased expression of IGFBP4 mRNA |
CTD |
PMID:17178593 |
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NCBI chr10:83,995,253...84,007,272
Ensembl chr10:83,989,591...84,007,225
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G |
Igfbp5 |
insulin-like growth factor binding protein 5 |
multiple interactions increases expression |
EXP |
Glucosamine inhibits the reaction [IL1B results in increased expression of IGFBP5 mRNA] Glucosamine results in increased expression of IGFBP5 mRNA |
CTD |
PMID:17109745 |
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NCBI chr 9:74,452,371...74,464,953
Ensembl chr 9:74,448,382...74,465,156
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G |
Ikbkb |
inhibitor of nuclear factor kappa B kinase subunit beta |
multiple interactions |
ISO |
Glucosamine analog inhibits the reaction [Lipopolysaccharides results in increased expression of IKBKB protein] |
CTD |
PMID:18786831 |
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NCBI chr16:69,319,487...69,373,251
Ensembl chr16:69,319,554...69,373,250
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G |
Ikbkg |
inhibitor of nuclear factor kappa B kinase regulatory subunit gamma |
multiple interactions decreases expression |
EXP |
Glucosamine inhibits the reaction [IL1B results in increased expression of IKBKG mRNA]; IL1B affects the reaction [Glucosamine results in decreased expression of IKBKG mRNA] |
CTD |
PMID:17109745 |
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NCBI chr X:152,216,485...152,241,476
Ensembl chr X:152,216,596...152,239,499
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G |
Il11 |
interleukin 11 |
multiple interactions |
EXP |
Glucosamine inhibits the reaction [IL1B results in increased expression of IL11 mRNA] |
CTD |
PMID:17109745 |
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NCBI chr 1:69,069,829...69,076,129
Ensembl chr 1:69,068,137...69,076,129
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G |
Il13ra1 |
interleukin 13 receptor subunit alpha 1 |
multiple interactions decreases expression |
EXP |
Glucosamine inhibits the reaction [IL1B results in increased expression of IL13RA1 mRNA] Glucosamine results in decreased expression of IL13RA1 mRNA |
CTD |
PMID:17109745 |
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NCBI chr X:115,348,822...115,408,682
Ensembl chr X:115,348,860...115,408,681 Ensembl chr11:115,348,860...115,408,681
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G |
Il1a |
interleukin 1 alpha |
multiple interactions increases expression |
EXP |
Glucosamine inhibits the reaction [IL1B results in increased expression of IL1A mRNA]; IL1B affects the reaction [Glucosamine results in increased expression of IL1A mRNA] |
CTD |
PMID:17109745 |
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NCBI chr 3:116,526,601...116,537,055
Ensembl chr 3:116,526,604...116,536,822
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G |
Il1b |
interleukin 1 beta |
multiple interactions increases expression decreases expression |
ISO EXP |
[Glucosamine co-treated with Chondroitin Sulfates co-treated with IL1B protein] results in decreased expression of NOS2 protein; [Glucosamine co-treated with Chondroitin Sulfates co-treated with IL1B protein] results in decreased expression of PTGES protein; [Glucosamine co-treated with Chondroitin Sulfates co-treated with IL1B protein] results in decreased expression of PTGS2 protein; [Glucosamine co-treated with Chondroitin Sulfates co-treated with IL1B protein] results in increased expression of TIMP3 mRNA; [Glucosamine co-treated with Chondroitin Sulfates] inhibits the reaction [IL1B protein results in increased secretion of Dinoprostone]; [Glucosamine co-treated with Chondroitin Sulfates] inhibits the reaction [IL1B protein results in increased secretion of Nitrites]; Glucosamine analog affects the reaction [IL1B protein results in increased abundance of Nitric Oxide]; Glucosamine analog affects the reaction [IL1B results in decreased expression of ACAN mRNA]; Glucosamine analog affects the reaction [IL1B results in decreased expression of COL2A1 mRNA]; Glucosamine analog affects the reaction [IL1B results in increased phosphorylation of AKT1 protein]; Glucosamine analog inhibits the reaction [IL1B protein results in increased abundance of Dinoprostone]; Glucosamine analog inhibits the reaction [IL1B protein results in increased expression of MMP13]; Glucosamine analog inhibits the reaction [IL1B protein results in increased expression of MMP1]; Glucosamine analog inhibits the reaction [IL1B protein results in increased expression of MMP3]; Glucosamine analog inhibits the reaction [IL1B results in increased expression of and results in increased secretion of MMP1 protein]; Glucosamine analog inhibits the reaction [IL1B results in increased expression of and results in increased secretion of MMP13 protein]; Glucosamine analog inhibits the reaction [IL1B results in increased expression of and results in increased secretion of MMP3 protein]; Glucosamine analog inhibits the reaction [IL1B results in increased expression of CXCL8 mRNA]; Glucosamine analog inhibits the reaction [IL1B results in increased expression of MMP1 mRNA]; Glucosamine analog inhibits the reaction [IL1B results in increased expression of MMP13 mRNA]; Glucosamine analog inhibits the reaction [IL1B results in increased expression of MMP3 mRNA]; Glucosamine analog inhibits the reaction [IL1B results in increased localization of RELA protein]; Glucosamine analog inhibits the reaction [IL1B results in increased phosphorylation of and results in increased degradation of NFKBIA protein]; Glucosamine analog inhibits the reaction [IL1B results in increased secretion of CCL2 protein]; Glucosamine analog inhibits the reaction [IL1B results in increased secretion of CCL5 protein]; Glucosamine analog inhibits the reaction [IL1B results in increased secretion of CXCL8 protein]; Glucosamine analog promotes the reaction [IL1B results in increased phosphorylation of MAPK1 protein]; Glucosamine analog promotes the reaction [IL1B results in increased phosphorylation of MAPK3 protein]; Glucosamine analog promotes the reaction [IL1B results in increased phosphorylation of MAPK8 protein]; Glucosamine inhibits the reaction [[OSM protein co-treated with IL1B protein] results in decreased methylation of IL1B promoter]; Glucosamine inhibits the reaction [[OSM protein co-treated with IL1B protein] results in increased expression of IL1B mRNA]; Glucosamine inhibits the reaction [IL1B promotes the reaction [TNF results in increased expression of ICAM1 protein]]; Glucosamine inhibits the reaction [IL1B protein results in decreased expression of ACAN mRNA]; Glucosamine inhibits the reaction [IL1B protein results in decreased expression of COL2A1 mRNA]; Glucosamine inhibits the reaction [IL1B protein results in increased activity of JUN protein]; Glucosamine inhibits the reaction [IL1B protein results in increased activity of JUND protein]; Glucosamine inhibits the reaction [IL1B protein results in increased degradation of NFKBIA protein]; Glucosamine inhibits the reaction [IL1B protein results in increased expression of COL1A1 mRNA]; Glucosamine inhibits the reaction [IL1B protein results in increased expression of MMP1 mRNA]; Glucosamine inhibits the reaction [IL1B protein results in increased expression of MMP13 mRNA]; Glucosamine inhibits the reaction [IL1B protein results in increased expression of MMP3 mRNA]; Glucosamine inhibits the reaction [IL1B protein results in increased expression of PTGS2 mRNA]; Glucosamine inhibits the reaction [IL1B protein results in increased expression of PTGS2 protein]; Glucosamine inhibits the reaction [IL1B protein results in increased localization of NFKB1 protein]; Glucosamine inhibits the reaction [IL1B protein results in increased localization of RELA protein]; Glucosamine inhibits the reaction [IL1B protein results in increased secretion of Dinoprostone]; Glucosamine inhibits the reaction [IL1B protein results in increased secretion of MMP1 protein]; Glucosamine inhibits the reaction [IL1B protein results in increased secretion of MMP13 protein]; Glucosamine inhibits the reaction [IL1B protein results in increased secretion of MMP3 protein]; Glucosamine inhibits the reaction [IL1B results in decreased expression of HMOX1 mRNA]; Glucosamine inhibits the reaction [IL1B results in decreased expression of HMOX1 protein]; Glucosamine inhibits the reaction [IL1B results in increased abundance of Dinoprostone]; Glucosamine inhibits the reaction [IL1B results in increased abundance of Nitric Oxide]; Glucosamine inhibits the reaction [IL1B results in increased abundance of Nitrites]; Glucosamine inhibits the reaction [IL1B results in increased degradation of NFKB1 protein]; Glucosamine inhibits the reaction [IL1B results in increased expression of CXCL8 mRNA]; Glucosamine inhibits the reaction [IL1B results in increased expression of CXCL8 protein]; Glucosamine inhibits the reaction [IL1B results in increased expression of ICAM1 mRNA]; Glucosamine inhibits the reaction [IL1B results in increased expression of ICAM1 protein]; Glucosamine inhibits the reaction [IL1B results in increased expression of MMP3 mRNA]; Glucosamine inhibits the reaction [IL1B results in increased expression of MMP3 protein]; Glucosamine inhibits the reaction [IL1B results in increased expression of NOS2 mRNA]; Glucosamine inhibits the reaction [IL1B results in increased expression of PTGES mRNA]; Glucosamine inhibits the reaction [IL1B results in increased localization of RELA protein]; Glucosamine inhibits the reaction [IL1B results in increased phosphorylation of MAPK1 protein]; Glucosamine inhibits the reaction [IL1B results in increased phosphorylation of MAPK14 protein]; Glucosamine inhibits the reaction [IL1B results in increased phosphorylation of MAPK3 protein]; Glucosamine inhibits the reaction [IL1B results in increased phosphorylation of MAPK8 protein]; Glucosamine inhibits the reaction [IL1B results in increased secretion of CXCL8 protein]; Glucosamine inhibits the reaction [TNF promotes the reaction [IL1B results in increased expression of ICAM1 protein]]; Glucosamine promotes the reaction [IL1B results in increased expression of PPARG]; Glucosamine promotes the reaction [IL1B results in increased phosphorylation of AKT1 protein]; Glucosamine promotes the reaction [Lipopolysaccharides results in increased expression of IL1B mRNA] Glucosamine results in increased expression of IL1B mRNA Glucosamine results in decreased expression of IL1B mRNA [IL1B protein co-treated with Glucosamine] results in increased expression of IL1R2 mRNA; Glucosamine affects the reaction [IL1B results in decreased expression of ADAM15 mRNA]; Glucosamine affects the reaction [IL1B results in decreased expression of OAT mRNA]; Glucosamine inhibits the reaction [IL1B protein results in decreased activity of B3GAT3 protein]; Glucosamine inhibits the reaction [IL1B protein results in decreased expression of B3GAT3 mRNA]; Glucosamine inhibits the reaction [IL1B protein results in increased abundance of Dinoprostone]; Glucosamine inhibits the reaction [IL1B protein results in increased abundance of Nitric Oxide]; Glucosamine inhibits the reaction [IL1B protein results in increased expression of MMP3 mRNA]; Glucosamine inhibits the reaction [IL1B results in decreased expression of ACAN mRNA]; Glucosamine inhibits the reaction [IL1B results in decreased expression of COL11A1 mRNA]; Glucosamine inhibits the reaction [IL1B results in decreased expression of COL2A1 mRNA]; Glucosamine inhibits the reaction [IL1B results in decreased expression of COL3A1 mRNA]; Glucosamine inhibits the reaction [IL1B results in decreased expression of FGFR1 mRNA]; Glucosamine inhibits the reaction [IL1B results in decreased expression of HAPLN1 mRNA]; Glucosamine inhibits the reaction [IL1B results in decreased expression of LAMA4 mRNA]; Glucosamine inhibits the reaction [IL1B results in decreased expression of SDC2 mRNA]; Glucosamine inhibits the reaction [IL1B results in decreased expression of SOX4 mRNA]; Glucosamine inhibits the reaction [IL1B results in decreased expression of THBS4 mRNA]; Glucosamine inhibits the reaction [IL1B results in decreased expression of TIMP2 mRNA]; Glucosamine inhibits the reaction [IL1B results in decreased expression of TIMP3 mRNA]; Glucosamine inhibits the reaction [IL1B results in increased expression of ADAM17 mRNA]; Glucosamine inhibits the reaction [IL1B results in increased expression of ADAMTS1 mRNA]; Glucosamine inhibits the reaction [IL1B results in increased expression of ASS1 mRNA]; Glucosamine inhibits the reaction [IL1B results in increased expression of BGN mRNA]; Glucosamine inhibits the reaction [IL1B results in increased expression of BMP2 mRNA]; Glucosamine inhibits the reaction [IL1B results in increased expression of BMP6 mRNA]; Glucosamine inhibits the reaction [IL1B results in increased expression of BMP7 mRNA]; Glucosamine inhibits the reaction [IL1B results in increased expression of CCL2 mRNA]; Glucosamine inhibits the reaction [IL1B results in increased expression of CCL20 mRNA]; Glucosamine inhibits the reaction [IL1B results in increased expression of CCL22 mRNA]; Glucosamine inhibits the reaction [IL1B results in increased expression of CCL3 mRNA]; Glucosamine inhibits the reaction [IL1B results in increased expression of CCL5 mRNA]; Glucosamine inhibits the reaction [IL1B results in increased expression of CCL7 mRNA]; Glucosamine inhibits the reaction [IL1B results in increased expression of COL8A1 mRNA]; Glucosamine inhibits the reaction [IL1B results in increased expression of CSF1 mRNA]; Glucosamine inhibits the reaction [IL1B results in increased expression of CSF2 mRNA]; Glucosamine inhibits the reaction [IL1B results in increased expression of CSF3 mRNA]; Glucosamine inhibits the reaction [IL1B results in increased expression of CXCL1 mRNA]; Glucosamine inhibits the reaction [IL1B results in increased expression of CXCL10 mRNA]; Glucosamine inhibits the reaction [IL1B results in increased expression of CXCL11 mRNA]; Glucosamine inhibits the reaction [IL1B results in increased expression of CXCL2 mRNA]; Glucosamine inhibits the reaction [IL1B results in increased expression of CXCL3 mRNA]; Glucosamine inhibits the reaction [IL1B results in increased expression of CXCL5 mRNA]; Glucosamine inhibits the reaction [IL1B results in increased expression of DUSP5 mRNA]; Glucosamine inhibits the reaction [IL1B results in increased expression of DUSP7 mRNA]; Glucosamine inhibits the reaction [IL1B results in increased expression of EPAS1 mRNA]; Glucosamine inhibits the reaction [IL1B results in increased expression of FGF9 mRNA]; Glucosamine inhibits the reaction [IL1B results in increased expression of GREM1 mRNA]; Glucosamine inhibits the reaction [IL1B results in increased expression of IGFBP3 mRNA]; Glucosamine inhibits the reaction [IL1B results in increased expression of IGFBP5 mRNA]; Glucosamine inhibits the reaction [IL1B results in increased expression of IKBKG mRNA]; Glucosamine inhibits the reaction [IL1B results in increased expression of IL11 mRNA]; Glucosamine inhibits the reaction [IL1B results in increased expression of IL13RA1 mRNA]; Glucosamine inhibits the reaction [IL1B results in increased expression of IL1A mRNA]; Glucosamine inhibits the reaction [IL1B results in increased expression of IL1B mRNA]; Glucosamine inhibits the reaction [IL1B results in increased expression of IL23R mRNA]; Glucosamine inhibits the reaction [IL1B results in increased expression of IL6 mRNA]; Glucosamine inhibits the reaction [IL1B results in increased expression of JAK2 mRNA]; Glucosamine inhibits the reaction [IL1B results in increased expression of JUNB mRNA]; Glucosamine inhibits the reaction [IL1B results in increased expression of MMP10 mRNA]; Glucosamine inhibits the reaction [IL1B results in increased expression of MMP12 mRNA]; Glucosamine inhibits the reaction [IL1B results in increased expression of MMP13 mRNA]; Glucosamine inhibits the reaction [IL1B results in increased expression of MMP3 mRNA]; Glucosamine inhibits the reaction [IL1B results in increased expression of MMP9 mRNA]; Glucosamine inhibits the reaction [IL1B results in increased expression of NFKBIA mRNA]; Glucosamine inhibits the reaction [IL1B results in increased expression of NFKBIB mRNA]; Glucosamine inhibits the reaction [IL1B results in increased expression of NGF mRNA]; Glucosamine inhibits the reaction [IL1B results in increased expression of NOS2 mRNA]; Glucosamine inhibits the reaction [IL1B results in increased expression of PDGFA mRNA]; Glucosamine inhibits the reaction [IL1B results in increased expression of PLA2G2A mRNA]; Glucosamine inhibits the reaction [IL1B results in increased expression of PLA2G4A mRNA]; Glucosamine inhibits the reaction [IL1B results in increased expression of PLA2G5 mRNA]; Glucosamine inhibits the reaction [IL1B results in increased expression of RELB mRNA]; Glucosamine inhibits the reaction [IL1B results in increased expression of SDC4 mRNA]; Glucosamine inhibits the reaction [IL1B results in increased expression of SLC7A8 mRNA]; Glucosamine inhibits the reaction [IL1B results in increased expression of TIMP1 mRNA]; Glucosamine inhibits the reaction [IL1B results in increased expression of TNFAIP6 mRNA]; Glucosamine inhibits the reaction [IL1B results in increased expression of TNK2 mRNA]; Glucosamine inhibits the reaction [IL1B results in increased expression of VCAN mRNA]; Glucosamine inhibits the reaction [Lipopolysaccharides results in increased expression of IL1B mRNA]; Glucosamine promotes the reaction [IL1B results in decreased expression of BMP4 mRNA]; Glucosamine promotes the reaction [IL1B results in decreased expression of CXCL12 mRNA]; IL1B affects the reaction [Glucosamine affects the expression of PDGFA mRNA]; IL1B affects the reaction [Glucosamine results in decreased expression of ADAM15 mRNA]; IL1B affects the reaction [Glucosamine results in decreased expression of BGN mRNA]; IL1B affects the reaction [Glucosamine results in decreased expression of COL11A1 mRNA]; IL1B affects the reaction [Glucosamine results in decreased expression of CXCL12 mRNA]; IL1B affects the reaction [Glucosamine results in decreased expression of DUSP7 mRNA]; IL1B affects the reaction [Glucosamine results in decreased expression of EPAS1 mRNA]; IL1B affects the reaction [Glucosamine results in decreased expression of IKBKG mRNA]; IL1B affects the reaction [Glucosamine results in decreased expression of JUNB mRNA]; IL1B affects the reaction [Glucosamine results in decreased expression of TNFAIP6 mRNA]; IL1B affects the reaction [Glucosamine results in decreased expression of VCAN mRNA]; IL1B affects the reaction [Glucosamine results in increased expression of ADAM17 mRNA]; IL1B affects the reaction [Glucosamine results in increased expression of IL1A mRNA]; IL1B affects the reaction [Glucosamine results in increased expression of JAK2 mRNA]; IL1B affects the reaction [Glucosamine results in increased expression of LAMA4 mRNA]; IL1B affects the reaction [Glucosamine results in increased expression of MMP9 mRNA]; IL1B affects the reaction [Glucosamine results in increased expression of NFKBIB mRNA]; IL1B affects the reaction [Glucosamine results in increased expression of TIMP3 mRNA]; IL1B inhibits the reaction [Glucosamine results in decreased expression of ADAMTS1 mRNA]; IL1B inhibits the reaction [Glucosamine results in decreased expression of COL8A1 mRNA]; IL1B inhibits the reaction [Glucosamine results in decreased expression of CSF1 mRNA]; IL1B inhibits the reaction [Glucosamine results in decreased expression of CXCL1 mRNA]; IL1B inhibits the reaction [Glucosamine results in decreased expression of FGF7 mRNA]; IL1B inhibits the reaction [Glucosamine results in decreased expression of GREM1 mRNA]; IL1B inhibits the reaction [Glucosamine results in decreased expression of NFKBIA mRNA]; IL1B inhibits the reaction [Glucosamine results in decreased expression of PLA2G2A mRNA]; IL1B inhibits the reaction [Glucosamine results in decreased expression of PLA2G5 mRNA]; IL1B inhibits the reaction [Glucosamine results in decreased expression of SDC4 mRNA]; IL1B inhibits the reaction [Glucosamine results in decreased expression of SLC7A8 mRNA]; IL1B inhibits the reaction [Glucosamine results in increased expression of IGFBP3 mRNA]; IL1B promotes the reaction [Glucosamine results in decreased expression of HAPLN1 mRNA]; IL1B promotes the reaction [Glucosamine results in decreased expression of SDC2 mRNA]; IL1B promotes the reaction [Glucosamine results in decreased expression of THBS4 mRNA]; IL1B promotes the reaction [Glucosamine results in increased expression of AZIN1 mRNA]; IL1B promotes the reaction [Glucosamine results in increased expression of CCL2 mRNA]; IL1B promotes the reaction [Glucosamine results in increased expression of CCL20 mRNA]; IL1B promotes the reaction [Glucosamine results in increased expression of CCL7 mRNA]; IL1B promotes the reaction [Glucosamine results in increased expression of CXCL2 mRNA]; IL1B promotes the reaction [Glucosamine results in increased expression of CXCL3 mRNA]; IL1B promotes the reaction [Glucosamine results in increased expression of MMP10 mRNA]; IL1B promotes the reaction [Glucosamine results in increased expression of MMP12 mRNA]; IL1B promotes the reaction [Glucosamine results in increased expression of MMP13 mRNA]; IL1B promotes the reaction [Glucosamine results in increased expression of MMP2 mRNA]; IL1B promotes the reaction [Glucosamine results in increased expression of MMP3 mRNA]; IL1B promotes the reaction [Glucosamine results in increased expression of NOS2 mRNA]; IL1B promotes the reaction [Glucosamine results in increased expression of TIMP1 mRNA] Glucosamine analog inhibits the reaction [Lipopolysaccharides results in increased expression of and results in increased secretion of IL1B protein]; Glucosamine inhibits the reaction [Lipopolysaccharides results in increased expression of IL1B mRNA] |
CTD |
PMID:11229466 PMID:11801247 PMID:12681956 PMID:15144122 PMID:16822504 PMID:17109745 PMID:17238806 PMID:17337215 PMID:17605605 PMID:17925024 PMID:18026701 PMID:18077487 PMID:18080321 PMID:18321735 PMID:18340449 PMID:18786831 PMID:19626664 PMID:19656660 PMID:20737476 PMID:21219853 PMID:22089456 PMID:38437956 More...
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NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415
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G |
Il1r2 |
interleukin 1 receptor type 2 |
multiple interactions |
EXP |
[IL1B protein co-treated with Glucosamine] results in increased expression of IL1R2 mRNA |
CTD |
PMID:11801247 |
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NCBI chr 9:42,384,280...42,424,726
Ensembl chr 9:42,384,433...42,424,725
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G |
Il2 |
interleukin 2 |
decreases secretion |
ISO |
Glucosamine results in decreased secretion of IL2 protein |
CTD |
PMID:14507305 |
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NCBI chr 2:120,004,862...120,009,566
Ensembl chr 2:120,004,862...120,009,566
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G |
Il23r |
interleukin 23 receptor |
multiple interactions |
EXP |
Glucosamine inhibits the reaction [IL1B results in increased expression of IL23R mRNA] |
CTD |
PMID:17109745 |
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NCBI chr 4:96,580,568...96,672,540
Ensembl chr 4:96,580,714...96,674,021
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G |
Il33 |
interleukin 33 |
decreases expression |
EXP |
Glucosamine results in decreased expression of IL33 mRNA |
CTD |
PMID:17109745 |
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NCBI chr 1:227,701,964...227,736,374
Ensembl chr 1:227,721,435...227,736,373
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G |
Il4 |
interleukin 4 |
decreases secretion decreases expression |
ISO |
Glucosamine results in decreased secretion of IL4 protein Glucosamine results in decreased expression of IL4 |
CTD |
PMID:14507305 PMID:21284687 |
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NCBI chr10:37,771,203...37,776,750
Ensembl chr10:37,771,203...37,776,750
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G |
Il5 |
interleukin 5 |
decreases secretion decreases expression |
ISO |
Glucosamine results in decreased secretion of IL5 protein Glucosamine results in decreased expression of IL5 |
CTD |
PMID:14507305 PMID:21284687 |
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NCBI chr10:37,874,342...37,877,213
Ensembl chr10:37,874,342...37,877,213
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G |
Il6 |
interleukin 6 |
multiple interactions decreases expression |
ISO EXP |
Glucosamine analog inhibits the reaction [TNF results in increased expression of IL6 mRNA]; Glucosamine inhibits the reaction [[IL6 co-treated with TNF] results in increased expression of ICAM1 protein]; Glucosamine inhibits the reaction [IL6 results in increased expression of ICAM1 protein]; Glucosamine inhibits the reaction [Lipopolysaccharides results in increased expression of and results in increased secretion of IL6 protein]; Glucosamine inhibits the reaction [Lipopolysaccharides results in increased expression of IL6 mRNA]; Glucosamine inhibits the reaction [TNF results in increased expression of IL6 mRNA]; Glucosamine promotes the reaction [Lipopolysaccharides results in increased expression of IL6 mRNA] Glucosamine inhibits the reaction [IL1B results in increased expression of IL6 mRNA]; Glucosamine inhibits the reaction [Lipopolysaccharides results in increased secretion of IL6 protein] Glucosamine analog results in decreased expression of IL6 mRNA; Glucosamine results in decreased expression of IL6 mRNA Glucosamine analog inhibits the reaction [Lipopolysaccharides results in increased expression of and results in increased secretion of IL6 protein]; Glucosamine inhibits the reaction [Lipopolysaccharides results in increased expression of IL6 mRNA] |
CTD |
PMID:16822504 PMID:17109745 PMID:18786831 PMID:19098112 PMID:20093129 PMID:20113495 PMID:20307528 PMID:20737476 PMID:38437956 More...
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NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178
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G |
Inpp5k |
inositol polyphosphate-5-phosphatase K |
multiple interactions increases expression |
ISO |
NUS1 protein inhibits the reaction [Glucosamine results in increased expression of INPP5K mRNA] |
CTD |
PMID:33812996 |
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NCBI chr10:60,474,262...60,495,813
Ensembl chr10:60,475,897...60,496,773
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G |
Ins1 |
insulin 1 |
multiple interactions |
EXP ISO |
4-phenylbutyric acid inhibits the reaction [Glucosamine inhibits the reaction [INS1 results in increased uptake of Deoxyglucose]]; [Glucosamine co-treated with INS1 protein] affects the localization of GFPT1 protein; Glucosamine inhibits the reaction [Glucose results in increased secretion of INS1 protein]; Glucosamine inhibits the reaction [INS1 protein results in increased uptake of Deoxyglucose]; Glucosamine inhibits the reaction [INS1 results in increased uptake of Deoxyglucose]; ursodoxicoltaurine inhibits the reaction [Glucosamine inhibits the reaction [INS1 results in increased uptake of Deoxyglucose]] [INS1 protein co-treated with Glucosamine] results in increased expression of OSTN mRNA; Glucosamine inhibits the reaction [INS1 protein results in increased phosphorylation of AKT1 protein]; Glucosamine inhibits the reaction [INS1 protein results in increased uptake of 2-(N-(7-nitrobenz-2-oxa-1,3-diazol-4-yl)amino)-2-deoxyglucose]; INS1 inhibits the reaction [[Streptozocin co-treated with APOE mutant form] results in increased abundance of Glucosamine]; OSTN protein affects the reaction [Glucosamine inhibits the reaction [INS1 protein results in increased phosphorylation of AKT1 protein]]; OSTN protein affects the reaction [Glucosamine inhibits the reaction [INS1 protein results in increased uptake of 2-(N-(7-nitrobenz-2-oxa-1,3-diazol-4-yl)amino)-2-deoxyglucose]] |
CTD |
PMID:9453242 PMID:11893929 PMID:16380481 PMID:20165829 PMID:30602124 |
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NCBI chr 1:251,244,973...251,245,540
Ensembl chr 1:251,244,973...251,245,536
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G |
Ins2 |
insulin 2 |
multiple interactions |
ISO |
4-phenylbutyric acid inhibits the reaction [Glucosamine inhibits the reaction [INS results in increased uptake of Deoxyglucose]]; Glucosamine inhibits the reaction [INS protein results in increased phosphorylation of GSK3B protein]; Glucosamine inhibits the reaction [INS results in increased uptake of Deoxyglucose]; NUS1 protein inhibits the reaction [Glucosamine inhibits the reaction [INS protein results in increased phosphorylation of GSK3B protein]]; PRKAA1 protein promotes the reaction [Glucosamine inhibits the reaction [INS protein results in increased phosphorylation of GSK3B protein]]; PRKAA1 protein promotes the reaction [NUS1 protein inhibits the reaction [Glucosamine inhibits the reaction [INS protein results in increased phosphorylation of GSK3B protein]]]; ursodoxicoltaurine inhibits the reaction [Glucosamine inhibits the reaction [INS results in increased uptake of Deoxyglucose]] |
CTD |
PMID:20165829 PMID:33812996 |
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NCBI chr 1:197,843,277...197,992,522
Ensembl chr 1:197,843,281...197,864,775
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G |
Irf1 |
interferon regulatory factor 1 |
multiple interactions |
ISO |
Glucosamine inhibits the reaction [Lipopolysaccharides results in increased expression of IRF1 mRNA] |
CTD |
PMID:20737476 |
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NCBI chr10:37,917,155...37,924,166
Ensembl chr10:37,916,670...37,924,166
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G |
Isyna1 |
inositol-3-phosphate synthase 1 |
increases expression |
EXP |
Glucosamine results in increased expression of ISYNA1 mRNA |
CTD |
PMID:17109745 |
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NCBI chr16:18,839,143...18,841,979
Ensembl chr16:18,839,145...18,841,979
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G |
Jak2 |
Janus kinase 2 |
multiple interactions increases expression |
EXP ISO |
Glucosamine inhibits the reaction [IL1B results in increased expression of JAK2 mRNA]; IL1B affects the reaction [Glucosamine results in increased expression of JAK2 mRNA] [Glucosamine co-treated with Lipopolysaccharides] results in increased phosphorylation of JAK2 protein |
CTD |
PMID:17109745 PMID:38437956 |
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NCBI chr 1:226,995,334...227,054,381
Ensembl chr 1:226,995,334...227,054,189
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G |
Jun |
Jun proto-oncogene, AP-1 transcription factor subunit |
multiple interactions |
ISO |
Glucosamine inhibits the reaction [IL1B protein results in increased activity of JUN protein] Glucosamine analog inhibits the reaction [Buthionine Sulfoximine results in increased expression of JUN mRNA] |
CTD |
PMID:17925024 PMID:21825963 |
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NCBI chr 5:109,894,175...109,897,268
Ensembl chr 5:109,893,145...109,897,656
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G |
Junb |
JunB proto-oncogene, AP-1 transcription factor subunit |
multiple interactions decreases expression |
EXP |
Glucosamine inhibits the reaction [IL1B results in increased expression of JUNB mRNA]; IL1B affects the reaction [Glucosamine results in decreased expression of JUNB mRNA] |
CTD |
PMID:17109745 |
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NCBI chr19:23,176,265...23,178,049
Ensembl chr19:23,176,294...23,178,035
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G |
Jund |
JunD proto-oncogene, AP-1 transcription factor subunit |
multiple interactions |
ISO |
Glucosamine inhibits the reaction [IL1B protein results in increased activity of JUND protein] |
CTD |
PMID:17925024 |
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NCBI chr16:18,734,121...18,735,799
Ensembl chr16:18,734,122...18,735,799
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G |
Kcnj16 |
potassium inwardly-rectifying channel, subfamily J, member 16 |
increases expression |
ISO |
Glucosamine results in increased expression of KCNJ16 mRNA |
CTD |
PMID:17178593 |
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NCBI chr10:95,990,009...96,021,356
Ensembl chr10:95,960,725...96,021,702
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G |
Kif11 |
kinesin family member 11 |
decreases expression |
EXP |
Glucosamine results in decreased expression of KIF11 mRNA |
CTD |
PMID:17109745 |
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NCBI chr 1:235,124,371...235,176,760
Ensembl chr 1:235,124,316...235,176,766
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G |
Kif4a |
kinesin family member 4A |
decreases expression |
EXP |
Glucosamine results in decreased expression of KIF4A mRNA |
CTD |
PMID:17109745 |
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NCBI chr X:65,721,746...65,824,277
Ensembl chr X:65,721,779...65,824,139
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G |
Klf10 |
KLF transcription factor 10 |
increases expression |
ISO |
Glucosamine results in increased expression of KLF10 mRNA |
CTD |
PMID:17178593 |
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NCBI chr 7:69,467,658...69,473,726
Ensembl chr 7:69,465,619...69,473,994
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G |
Lama4 |
laminin subunit alpha 4 |
multiple interactions increases expression |
EXP |
Glucosamine inhibits the reaction [IL1B results in decreased expression of LAMA4 mRNA]; IL1B affects the reaction [Glucosamine results in increased expression of LAMA4 mRNA] |
CTD |
PMID:17109745 |
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NCBI chr20:42,392,268...42,533,347
Ensembl chr20:42,392,268...42,533,347
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G |
Lamb1 |
laminin subunit beta 1 |
multiple interactions |
ISO |
TXNIP promotes the reaction [Glucosamine results in increased expression of LAMB1 mRNA] |
CTD |
PMID:17178593 |
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NCBI chr 6:47,835,492...47,902,585
Ensembl chr 6:47,835,525...47,902,585
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G |
Lamc1 |
laminin subunit gamma 1 |
multiple interactions |
ISO |
TXNIP promotes the reaction [Glucosamine results in increased expression of LAMC1 mRNA] |
CTD |
PMID:17178593 |
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NCBI chr13:65,374,372...65,501,492
Ensembl chr13:65,374,372...65,501,492
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G |
Lcn2 |
lipocalin 2 |
decreases expression |
ISO |
Glucosamine results in decreased expression of LCN2 mRNA |
CTD |
PMID:17178593 |
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NCBI chr 3:15,680,688...15,684,033
Ensembl chr 3:15,680,687...15,684,095
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G |
Lepr |
leptin receptor |
affects response to substance multiple interactions |
EXP |
LEPR protein affects the susceptibility to Glucosamine [LEPR protein affects the susceptibility to Glucosamine] which affects the expression of ALB protein |
CTD |
PMID:33345901 |
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NCBI chr 5:116,294,409...116,477,904
Ensembl chr 5:116,289,823...116,475,908
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G |
Lpin1 |
lipin 1 |
increases expression |
ISO |
Glucosamine results in increased expression of LPIN1 mRNA |
CTD |
PMID:17178593 |
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NCBI chr 6:39,309,198...39,417,034
Ensembl chr 6:39,312,748...39,417,097
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G |
Ly6a |
lymphocyte antigen 6 family member A |
increases expression |
ISO |
Glucosamine results in increased expression of LY6A mRNA |
CTD |
PMID:17178593 |
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NCBI chr 7:107,177,191...107,189,436
Ensembl chr 7:107,183,469...107,189,981
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G |
Mafb |
MAF bZIP transcription factor B |
increases expression |
EXP |
Glucosamine results in increased expression of MAFB mRNA |
CTD |
PMID:17109745 |
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NCBI chr 3:148,998,111...149,000,031
Ensembl chr 3:148,998,122...149,000,031
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G |
Mapk1 |
mitogen activated protein kinase 1 |
multiple interactions increases phosphorylation |
ISO |
Glucosamine analog inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of MAPK1 protein]; Glucosamine analog promotes the reaction [IL1B results in increased phosphorylation of MAPK1 protein]; Glucosamine inhibits the reaction [IL1B results in increased phosphorylation of MAPK1 protein]; Glucosamine inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of MAPK1 protein] Glucosamine analog results in increased phosphorylation of MAPK1 protein |
CTD |
PMID:18080321 PMID:18340449 PMID:19375915 PMID:19626664 PMID:20307528 |
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NCBI chr11:83,957,813...84,023,629
Ensembl chr11:83,957,813...84,023,616
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G |
Mapk14 |
mitogen activated protein kinase 14 |
multiple interactions |
ISO |
Glucosamine inhibits the reaction [IL1B results in increased phosphorylation of MAPK14 protein] |
CTD |
PMID:19626664 |
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NCBI chr20:6,749,646...6,810,590
Ensembl chr20:6,749,670...6,810,589
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G |
Mapk3 |
mitogen activated protein kinase 3 |
multiple interactions increases phosphorylation |
ISO |
Glucosamine analog inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of MAPK3 protein]; Glucosamine analog promotes the reaction [IL1B results in increased phosphorylation of MAPK3 protein]; Glucosamine inhibits the reaction [IL1B results in increased phosphorylation of MAPK3 protein]; Glucosamine inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of MAPK3 protein] Glucosamine analog results in increased phosphorylation of MAPK3 protein |
CTD |
PMID:18080321 PMID:18340449 PMID:19375915 PMID:19626664 PMID:20307528 |
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NCBI chr 1:181,366,646...181,372,863
Ensembl chr 1:181,366,637...181,372,863
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G |
Mapk8 |
mitogen-activated protein kinase 8 |
multiple interactions increases phosphorylation |
ISO |
Glucosamine analog promotes the reaction [IL1B results in increased phosphorylation of MAPK8 protein]; Glucosamine inhibits the reaction [IL1B results in increased phosphorylation of MAPK8 protein]; Glucosamine inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of MAPK8 protein] Glucosamine analog results in increased phosphorylation of MAPK8 protein |
CTD |
PMID:18080321 PMID:19626664 PMID:20307528 |
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NCBI chr16:8,638,897...8,721,960
Ensembl chr16:8,638,924...8,721,981
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G |
Mcl1 |
MCL1 apoptosis regulator, BCL2 family member |
decreases expression |
ISO |
Glucosamine results in decreased expression of MCL1 mRNA; Glucosamine results in decreased expression of MCL1 protein |
CTD |
PMID:22020377 |
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NCBI chr 2:183,219,137...183,235,676
Ensembl chr 2:183,219,220...183,222,303
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G |
Mef2a |
myocyte enhancer factor 2a |
multiple interactions decreases expression |
ISO EXP |
4-phenylbutyric acid inhibits the reaction [Glucosamine results in decreased expression of MEF2A mRNA]; 4-phenylbutyric acid inhibits the reaction [Glucosamine results in decreased expression of MEF2A protein]; ATF6 mutant form inhibits the reaction [Glucosamine results in decreased expression of MEF2A mRNA]; ATF6 mutant form inhibits the reaction [Glucosamine results in decreased expression of MEF2A protein]; ursodoxicoltaurine inhibits the reaction [Glucosamine results in decreased expression of MEF2A mRNA]; ursodoxicoltaurine inhibits the reaction [Glucosamine results in decreased expression of MEF2A protein] Glucosamine results in decreased expression of MEF2A mRNA; Glucosamine results in decreased expression of MEF2A protein |
CTD |
PMID:20165829 |
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NCBI chr 1:120,847,874...120,982,488
Ensembl chr 1:120,850,080...120,981,948
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G |
Mettl1 |
methyltransferase 1, tRNA methylguanosine |
decreases expression |
ISO |
Glucosamine results in decreased expression of METTL1 mRNA |
CTD |
PMID:17178593 |
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NCBI chr 7:62,864,860...62,869,202
Ensembl chr 7:62,864,853...62,869,202
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G |
Mfap3l |
microfibril associated protein 3 like |
increases expression |
ISO |
Glucosamine results in increased expression of MFAP3L mRNA |
CTD |
PMID:17178593 |
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NCBI chr16:29,411,643...29,454,665
Ensembl chr16:29,415,849...29,430,863
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G |
Mki67 |
marker of proliferation Ki-67 |
decreases expression |
EXP |
Glucosamine results in decreased expression of MKI67 mRNA |
CTD |
PMID:17109745 |
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NCBI chr 1:190,496,319...190,522,983
Ensembl chr 1:190,496,319...190,522,762
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G |
Mmp1 |
matrix metallopeptidase 1 |
multiple interactions |
ISO |
Glucosamine analog inhibits the reaction [IL1B protein results in increased expression of MMP1]; Glucosamine analog inhibits the reaction [IL1B results in increased expression of and results in increased secretion of MMP1 protein]; Glucosamine analog inhibits the reaction [IL1B results in increased expression of MMP1 mRNA]; Glucosamine inhibits the reaction [IL1B protein results in increased expression of MMP1 mRNA]; Glucosamine inhibits the reaction [IL1B protein results in increased secretion of MMP1 protein] |
CTD |
PMID:15144122 PMID:17925024 PMID:18080321 |
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NCBI chr 8:4,658,588...4,679,099
Ensembl chr 8:4,658,588...4,679,097
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G |
Mmp10 |
matrix metallopeptidase 10 |
increases expression multiple interactions |
EXP |
Glucosamine results in increased expression of MMP10 mRNA Glucosamine inhibits the reaction [IL1B results in increased expression of MMP10 mRNA]; IL1B promotes the reaction [Glucosamine results in increased expression of MMP10 mRNA] |
CTD |
PMID:17109745 |
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NCBI chr 8:4,689,840...4,697,748
Ensembl chr 8:4,689,840...4,697,748
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G |
Mmp12 |
matrix metallopeptidase 12 |
multiple interactions increases expression |
EXP |
Glucosamine inhibits the reaction [IL1B results in increased expression of MMP12 mRNA]; IL1B promotes the reaction [Glucosamine results in increased expression of MMP12 mRNA] |
CTD |
PMID:17109745 |
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NCBI chr 8:4,581,785...4,591,687
Ensembl chr 8:4,581,785...4,599,611
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G |
Mmp13 |
matrix metallopeptidase 13 |
affects expression multiple interactions increases expression |
ISO EXP |
Glucosamine analog affects the expression of MMP13 mRNA Glucosamine inhibits the reaction [IL1B results in increased expression of MMP13 mRNA]; IL1B promotes the reaction [Glucosamine results in increased expression of MMP13 mRNA] Glucosamine analog inhibits the reaction [IL1B protein results in increased expression of MMP13]; Glucosamine analog inhibits the reaction [IL1B results in increased expression of and results in increased secretion of MMP13 protein]; Glucosamine analog inhibits the reaction [IL1B results in increased expression of MMP13 mRNA]; Glucosamine analog inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of MMP13 mRNA]; Glucosamine inhibits the reaction [IL1B protein results in increased expression of MMP13 mRNA]; Glucosamine inhibits the reaction [IL1B protein results in increased secretion of MMP13 protein] |
CTD |
PMID:15144122 PMID:17109745 PMID:17337215 PMID:17925024 PMID:18080321 PMID:19656660 More...
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NCBI chr 8:4,497,960...4,508,239
Ensembl chr 8:4,497,960...4,508,239
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G |
Mmp2 |
matrix metallopeptidase 2 |
multiple interactions increases expression |
ISO EXP |
Glucosamine analog inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of and results in increased activity of MMP2 protein]; Glucosamine analog inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of MMP2 mRNA]; Glucosamine inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of MMP2 mRNA]; Glucosamine inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of MMP2 protein] IL1B promotes the reaction [Glucosamine results in increased expression of MMP2 mRNA] |
CTD |
PMID:17109745 PMID:17498959 PMID:19375915 |
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NCBI chr19:14,154,657...14,182,870
Ensembl chr19:14,154,657...14,182,870
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G |
Mmp3 |
matrix metallopeptidase 3 |
multiple interactions increases expression decreases expression |
ISO EXP |
[Glucosamine co-treated with Chondroitin Sulfates] results in decreased expression of MMP3 mRNA; [Glucosamine co-treated with Chondroitin Sulfates] results in decreased secretion of MMP3 protein; Glucosamine analog inhibits the reaction [IL1B protein results in increased expression of MMP3]; Glucosamine analog inhibits the reaction [IL1B results in increased expression of and results in increased secretion of MMP3 protein]; Glucosamine analog inhibits the reaction [IL1B results in increased expression of MMP3 mRNA]; Glucosamine inhibits the reaction [IL1B protein results in increased expression of MMP3 mRNA]; Glucosamine inhibits the reaction [IL1B protein results in increased secretion of MMP3 protein]; Glucosamine inhibits the reaction [IL1B results in increased expression of MMP3 mRNA]; Glucosamine inhibits the reaction [IL1B results in increased expression of MMP3 protein]; Glucosamine results in decreased expression of and results in decreased activity of MMP3 protein Glucosamine results in increased expression of MMP3 mRNA Glucosamine inhibits the reaction [IL1B protein results in increased expression of MMP3 mRNA]; Glucosamine inhibits the reaction [IL1B results in increased expression of MMP3 mRNA]; IL1B promotes the reaction [Glucosamine results in increased expression of MMP3 mRNA] Glucosamine analog results in decreased expression of MMP3 mRNA |
CTD |
PMID:11229466 PMID:12801482 PMID:15144122 PMID:16300972 PMID:17109745 PMID:17925024 PMID:18080321 PMID:18340449 PMID:20110869 More...
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NCBI chr 8:4,640,397...4,653,963
Ensembl chr 8:4,640,416...4,653,961
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G |
Mmp9 |
matrix metallopeptidase 9 |
multiple interactions increases expression |
ISO EXP |
Glucosamine analog inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of and results in increased activity of MMP9 protein]; Glucosamine analog inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of MMP9 mRNA]; Glucosamine inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of MMP9 mRNA]; Glucosamine inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of MMP9 protein] Glucosamine results in increased expression of MMP9 mRNA Glucosamine inhibits the reaction [IL1B results in increased expression of MMP9 mRNA]; IL1B affects the reaction [Glucosamine results in increased expression of MMP9 mRNA] |
CTD |
PMID:17109745 PMID:17498959 PMID:19375915 |
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NCBI chr 3:153,684,158...153,692,118
Ensembl chr 3:153,683,858...153,692,120
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G |
Mnda |
myeloid cell nuclear differentiation antigen |
increases expression |
ISO |
Glucosamine results in increased expression of IFI204 mRNA |
CTD |
PMID:17178593 |
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NCBI chr13:86,017,888...86,035,556
Ensembl chr13:86,017,892...86,034,201
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G |
Mpo |
myeloperoxidase |
decreases activity |
EXP |
Glucosamine results in decreased activity of MPO protein |
CTD |
PMID:19098112 |
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NCBI chr10:72,594,883...72,608,862
Ensembl chr10:72,594,661...72,604,819
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G |
Mvd |
mevalonate diphosphate decarboxylase |
increases expression |
ISO |
Glucosamine results in increased expression of MVD mRNA |
CTD |
PMID:17178593 |
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NCBI chr19:50,496,366...50,506,429
Ensembl chr19:50,496,367...50,507,971
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G |
Ndufa4 |
Ndufa4, mitochondrial complex associated |
increases expression |
EXP |
Glucosamine results in increased expression of NDUFA4 mRNA |
CTD |
PMID:17109745 |
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NCBI chr 4:40,002,216...40,009,384
Ensembl chr 4:40,002,216...40,023,920
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G |
Nedd4 |
NEDD4 E3 ubiquitin protein ligase |
decreases expression |
EXP |
Glucosamine results in decreased expression of NEDD4 mRNA |
CTD |
PMID:17109745 |
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NCBI chr 8:73,384,095...73,468,951
Ensembl chr 8:73,383,695...73,468,951
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G |
Nfkb1 |
nuclear factor kappa B subunit 1 |
multiple interactions decreases activity |
ISO EXP |
Glucosamine inhibits the reaction [Hydrogen Peroxide results in increased expression of and results in increased localization of NFKB1 protein]; Glucosamine inhibits the reaction [IL1B protein results in increased localization of NFKB1 protein]; Glucosamine inhibits the reaction [IL1B results in increased degradation of NFKB1 protein]; Glucosamine inhibits the reaction [NFKB1 results in increased degradation of RELA protein]; Glucosamine inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of NFKB1 protein] Glucosamine results in decreased activity of NFKB1 protein Glucosamine analog inhibits the reaction [Lipopolysaccharides results in increased expression of NFKB1 protein] |
CTD |
PMID:12681956 PMID:16431966 PMID:16822504 PMID:17498959 PMID:18036590 PMID:18205790 PMID:20737476 More...
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NCBI chr 2:224,016,214...224,132,135
Ensembl chr 2:224,016,214...224,110,404
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G |
Nfkbia |
NFKB inhibitor alpha |
multiple interactions decreases phosphorylation decreases expression |
ISO EXP |
Glucosamine analog inhibits the reaction [IL1B results in increased phosphorylation of and results in increased degradation of NFKBIA protein]; Glucosamine inhibits the reaction [IL1B protein results in increased degradation of NFKBIA protein] Glucosamine results in decreased phosphorylation of NFKBIA protein Glucosamine results in decreased expression of NFKBIA mRNA Glucosamine inhibits the reaction [IL1B results in increased expression of NFKBIA mRNA]; Glucosamine inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of NFKBIA protein]; IL1B inhibits the reaction [Glucosamine results in decreased expression of NFKBIA mRNA] Glucosamine analog inhibits the reaction [Lipopolysaccharides results in increased expression of NFKBIA protein modified form]; Glucosamine inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of NFKBIA protein] |
CTD |
PMID:12681956 PMID:17109745 PMID:18080321 PMID:18205790 PMID:19098112 |
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NCBI chr 6:72,858,713...72,861,941
Ensembl chr 6:72,858,712...72,861,941
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G |
Nfkbib |
NFKB inhibitor beta |
multiple interactions increases expression |
EXP |
Glucosamine inhibits the reaction [IL1B results in increased expression of NFKBIB mRNA]; IL1B affects the reaction [Glucosamine results in increased expression of NFKBIB mRNA] |
CTD |
PMID:17109745 |
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NCBI chr 1:84,046,292...84,053,862
Ensembl chr 1:84,046,295...84,053,862
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G |
Ngef |
neuronal guanine nucleotide exchange factor |
increases expression |
ISO |
Glucosamine results in increased expression of NGEF mRNA |
CTD |
PMID:17178593 |
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NCBI chr 9:88,146,956...88,244,454
Ensembl chr 9:88,146,956...88,244,914
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G |
Ngf |
nerve growth factor |
multiple interactions |
EXP |
Glucosamine inhibits the reaction [IL1B results in increased expression of NGF mRNA] |
CTD |
PMID:17109745 |
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NCBI chr 2:189,901,058...189,954,452
Ensembl chr 2:189,901,058...189,954,452
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G |
Nos2 |
nitric oxide synthase 2 |
multiple interactions increases expression decreases expression |
ISO EXP |
[Glucosamine co-treated with Chondroitin Sulfates co-treated with IL1B protein] results in decreased expression of NOS2 protein; Glucosamine inhibits the reaction [IL1B results in increased expression of NOS2 mRNA]; Glucosamine promotes the reaction [Lipopolysaccharides results in increased expression of NOS2 mRNA] Glucosamine results in increased expression of NOS2 mRNA Glucosamine inhibits the reaction [IL1B results in increased expression of NOS2 mRNA]; Glucosamine inhibits the reaction [Lipopolysaccharides results in increased expression of NOS2 mRNA]; IL1B promotes the reaction [Glucosamine results in increased expression of NOS2 mRNA] Glucosamine results in decreased expression of NOS2 mRNA Glucosamine analog inhibits the reaction [Lipopolysaccharides results in increased expression of NOS2 mRNA]; Glucosamine analog inhibits the reaction [Lipopolysaccharides results in increased expression of NOS2 protein]; Glucosamine inhibits the reaction [Lipopolysaccharides promotes the reaction [RELA protein binds to NOS2 promoter]]; Glucosamine inhibits the reaction [Lipopolysaccharides results in increased expression of NOS2 mRNA]; Glucosamine inhibits the reaction [Lipopolysaccharides results in increased expression of NOS2 protein] |
CTD |
PMID:17109745 PMID:17440993 PMID:17605605 PMID:18077487 PMID:18205790 PMID:19098112 PMID:20737476 PMID:38437956 More...
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NCBI chr10:63,815,308...63,851,208
Ensembl chr10:63,815,308...63,851,210
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G |
Nr1h4 |
nuclear receptor subfamily 1, group H, member 4 |
affects expression |
EXP |
Glucosamine affects the expression of NR1H4 |
CTD |
PMID:19373748 |
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NCBI chr 7:23,846,122...23,942,085
Ensembl chr 7:23,846,122...23,942,047
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G |
Nsdhl |
NAD(P) dependent steroid dehydrogenase-like |
increases expression |
ISO |
Glucosamine results in increased expression of NSDHL mRNA |
CTD |
PMID:17178593 |
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NCBI chr X:150,775,034...150,807,161
Ensembl chr X:150,775,080...150,807,142
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G |
Nucb2 |
nucleobindin 2 |
decreases expression |
ISO |
Glucosamine results in decreased expression of NUCB2 mRNA |
CTD |
PMID:17178593 |
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NCBI chr 1:170,750,830...170,787,356
Ensembl chr 1:170,750,877...170,787,353
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G |
Nuf2 |
NUF2 component of NDC80 kinetochore complex |
decreases expression |
EXP |
Glucosamine results in decreased expression of NUF2 mRNA |
CTD |
PMID:17109745 |
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NCBI chr13:81,693,675...81,722,765
Ensembl chr13:81,693,598...81,722,766
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G |
Nus1 |
NUS1 dehydrodolichyl diphosphate synthase subunit |
multiple interactions |
ISO |
NUS1 protein inhibits the reaction [Glucosamine inhibits the reaction [INS protein results in increased phosphorylation of GSK3B protein]]; NUS1 protein inhibits the reaction [Glucosamine results in increased expression of ATF4 mRNA]; NUS1 protein inhibits the reaction [Glucosamine results in increased expression of ATF6 mRNA]; NUS1 protein inhibits the reaction [Glucosamine results in increased expression of DDIT3 mRNA]; NUS1 protein inhibits the reaction [Glucosamine results in increased expression of EIF2AK3 protein]; NUS1 protein inhibits the reaction [Glucosamine results in increased expression of ERN1 mRNA]; NUS1 protein inhibits the reaction [Glucosamine results in increased expression of HSPA5 mRNA]; NUS1 protein inhibits the reaction [Glucosamine results in increased expression of HSPA5 protein]; NUS1 protein inhibits the reaction [Glucosamine results in increased expression of INPP5K mRNA]; NUS1 protein inhibits the reaction [Glucosamine results in increased phosphorylation of EIF2S1 protein]; NUS1 protein inhibits the reaction [Glucosamine results in increased splicing of XBP1 mRNA]; PRKAA1 protein promotes the reaction [NUS1 protein inhibits the reaction [Glucosamine inhibits the reaction [INS protein results in increased phosphorylation of GSK3B protein]]] |
CTD |
PMID:33812996 |
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NCBI chr20:31,811,817...31,838,562
Ensembl chr20:31,811,817...31,838,561
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G |
Oat |
ornithine aminotransferase |
multiple interactions |
EXP |
Glucosamine affects the reaction [IL1B results in decreased expression of OAT mRNA] |
CTD |
PMID:17109745 |
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NCBI chr 1:187,347,862...187,367,644
Ensembl chr 1:187,347,865...187,367,682
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G |
Ogt |
O-linked N-acetylglucosamine (GlcNAc) transferase |
decreases expression |
ISO |
Glucosamine results in decreased expression of OGT mRNA |
CTD |
PMID:17178593 |
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NCBI chr X:66,771,278...66,816,148
Ensembl chr X:66,771,349...66,816,146
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G |
Orc2 |
origin recognition complex, subunit 2 |
decreases expression |
ISO |
Glucosamine results in decreased expression of ORC2 mRNA |
CTD |
PMID:17178593 |
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NCBI chr 9:60,001,631...60,038,301
Ensembl chr 9:60,001,910...60,038,195
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G |
Osm |
oncostatin M |
multiple interactions |
ISO |
Glucosamine inhibits the reaction [[OSM protein co-treated with IL1B protein] results in decreased methylation of IL1B promoter]; Glucosamine inhibits the reaction [[OSM protein co-treated with IL1B protein] results in increased expression of IL1B mRNA] |
CTD |
PMID:21219853 |
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NCBI chr14:79,103,638...79,108,500
Ensembl chr14:79,104,344...79,108,313
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G |
Ostn |
osteocrin |
increases expression multiple interactions |
ISO |
Glucosamine results in increased expression of OSTN mRNA 4-methylumbelliferone 8-carbaldehyde inhibits the reaction [Glucosamine results in increased expression of OSTN mRNA]; 4-phenylbutyric acid inhibits the reaction [Glucosamine results in increased expression of OSTN mRNA]; [INS1 protein co-treated with Glucosamine] results in increased expression of OSTN mRNA; ATF6 protein affects the reaction [Glucosamine results in increased expression of OSTN mRNA]; EIF2AK3 protein affects the reaction [Glucosamine results in increased expression of OSTN mRNA]; ERN1 protein affects the reaction [Glucosamine results in increased expression of OSTN mRNA]; GSK2656157 inhibits the reaction [Glucosamine results in increased expression of OSTN mRNA]; OSTN protein affects the reaction [Glucosamine inhibits the reaction [INS1 protein results in increased phosphorylation of AKT1 protein]]; OSTN protein affects the reaction [Glucosamine inhibits the reaction [INS1 protein results in increased uptake of 2-(N-(7-nitrobenz-2-oxa-1,3-diazol-4-yl)amino)-2-deoxyglucose]] |
CTD |
PMID:30602124 |
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NCBI chr11:73,442,167...73,478,498
Ensembl chr11:73,442,487...73,468,603
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G |
Oxr1 |
oxidation resistance 1 |
decreases expression |
ISO |
Glucosamine results in decreased expression of OXR1 mRNA |
CTD |
PMID:17178593 |
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NCBI chr 7:72,528,750...72,965,666
Ensembl chr 7:72,528,786...72,965,666
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G |
Pank1 |
pantothenate kinase 1 |
increases expression |
ISO |
Glucosamine results in increased expression of PANK1 mRNA |
CTD |
PMID:17178593 |
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NCBI chr 1:232,324,718...232,395,445
Ensembl chr 1:232,328,430...232,396,829
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G |
Parp1 |
poly (ADP-ribose) polymerase 1 |
increases cleavage multiple interactions |
ISO |
Glucosamine results in increased cleavage of PARP1 protein pepstatin inhibits the reaction [Glucosamine results in increased cleavage of PARP1 protein] |
CTD |
PMID:16850161 |
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NCBI chr13:92,307,593...92,339,406
Ensembl chr13:92,307,586...92,339,404
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G |
Pdgfa |
platelet derived growth factor subunit A |
affects expression multiple interactions |
EXP |
Glucosamine affects the expression of PDGFA mRNA Glucosamine inhibits the reaction [IL1B results in increased expression of PDGFA mRNA]; IL1B affects the reaction [Glucosamine affects the expression of PDGFA mRNA] |
CTD |
PMID:17109745 |
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NCBI chr12:15,645,549...15,667,056
Ensembl chr12:15,645,541...15,666,497
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G |
Pdia4 |
protein disulfide isomerase family A, member 4 |
decreases expression |
ISO |
Glucosamine results in decreased expression of PDIA4 mRNA |
CTD |
PMID:17178593 |
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NCBI chr 4:76,803,198...76,822,245
Ensembl chr 4:76,803,198...76,822,107
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G |
Pdia6 |
protein disulfide isomerase family A, member 6 |
decreases expression |
ISO |
Glucosamine results in decreased expression of PDIA6 mRNA |
CTD |
PMID:17178593 |
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NCBI chr 6:40,062,980...40,080,223
Ensembl chr 6:40,062,926...40,080,613
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G |
Pdk4 |
pyruvate dehydrogenase kinase 4 |
increases expression |
ISO |
Glucosamine results in increased expression of PDK4 mRNA |
CTD |
PMID:17178593 |
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NCBI chr 4:33,591,796...33,601,798
Ensembl chr 4:33,589,799...33,601,850
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G |
Pfkp |
phosphofructokinase, platelet |
increases expression |
ISO |
Glucosamine results in increased expression of PFKP mRNA |
CTD |
PMID:17178593 |
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NCBI chr17:63,729,743...63,794,026
Ensembl chr17:63,729,780...63,794,018
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G |
Piga |
phosphatidylinositol glycan anchor biosynthesis, class A |
decreases expression |
ISO |
Glucosamine results in decreased expression of PIGA mRNA |
CTD |
PMID:17178593 |
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NCBI chr X:30,043,033...30,055,861
Ensembl chr X:30,042,343...30,055,804
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G |
Pla2g2a |
phospholipase A2 group IIA |
multiple interactions decreases expression |
EXP |
Glucosamine inhibits the reaction [IL1B results in increased expression of PLA2G2A mRNA]; IL1B inhibits the reaction [Glucosamine results in decreased expression of PLA2G2A mRNA] |
CTD |
PMID:17109745 |
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NCBI chr 5:151,076,442...151,079,019
Ensembl chr 5:151,076,442...151,079,014
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G |
Pla2g4a |
phospholipase A2 group 4A |
affects expression multiple interactions |
EXP |
Glucosamine affects the expression of PLA2G4A mRNA Glucosamine inhibits the reaction [IL1B results in increased expression of PLA2G4A mRNA] |
CTD |
PMID:17109745 |
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NCBI chr13:61,877,818...62,022,261
Ensembl chr13:61,877,813...62,022,266
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G |
Pla2g5 |
phospholipase A2, group V |
multiple interactions decreases expression |
EXP |
Glucosamine inhibits the reaction [IL1B results in increased expression of PLA2G5 mRNA]; IL1B inhibits the reaction [Glucosamine results in decreased expression of PLA2G5 mRNA] |
CTD |
PMID:17109745 |
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NCBI chr 5:151,041,339...151,109,433
Ensembl chr 5:151,041,340...151,062,658
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G |
Plat |
plasminogen activator, tissue type |
increases expression |
ISO |
Glucosamine results in increased expression of PLAT mRNA |
CTD |
PMID:17178593 |
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NCBI chr16:69,240,582...69,265,177
Ensembl chr16:69,240,585...69,268,223
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G |
Plk1 |
polo-like kinase 1 |
increases expression decreases expression |
ISO EXP |
Glucosamine results in increased expression of PLK1 mRNA Glucosamine results in decreased expression of PLK1 mRNA |
CTD |
PMID:17109745 PMID:17178593 |
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NCBI chr 1:176,716,420...176,726,400
Ensembl chr 1:176,716,420...176,726,400
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G |
Plpp3 |
phospholipid phosphatase 3 |
decreases expression |
EXP |
Glucosamine results in decreased expression of PLPP3 mRNA |
CTD |
PMID:17109745 |
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NCBI chr 5:119,927,085...120,002,206
Ensembl chr 5:119,927,085...120,002,205
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G |
Pparg |
peroxisome proliferator-activated receptor gamma |
multiple interactions increases expression |
ISO EXP |
Glucosamine promotes the reaction [IL1B results in increased expression of PPARG] Glucosamine results in increased expression of PPARG mRNA |
CTD |
PMID:15694357 PMID:22089456 |
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NCBI chr 4:148,423,102...148,548,471
Ensembl chr 4:148,423,194...148,548,468
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G |
Ppargc1a |
PPARG coactivator 1 alpha |
multiple interactions decreases expression |
ISO EXP |
4-phenylbutyric acid inhibits the reaction [Glucosamine results in decreased expression of PPARGC1A mRNA]; 4-phenylbutyric acid inhibits the reaction [Glucosamine results in decreased expression of PPARGC1A protein]; ATF6 mutant form inhibits the reaction [Glucosamine results in decreased expression of PPARGC1A mRNA]; ATF6 mutant form inhibits the reaction [Glucosamine results in decreased expression of PPARGC1A protein]; ursodoxicoltaurine inhibits the reaction [Glucosamine results in decreased expression of PPARGC1A mRNA]; ursodoxicoltaurine inhibits the reaction [Glucosamine results in decreased expression of PPARGC1A protein] Glucosamine results in decreased expression of PPARGC1A mRNA; Glucosamine results in decreased expression of PPARGC1A protein |
CTD |
PMID:20165829 |
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NCBI chr14:58,860,752...59,516,525
Ensembl chr14:58,861,144...59,512,656
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G |
Ppm1a |
protein phosphatase, Mg2+/Mn2+ dependent, 1A |
decreases expression |
ISO |
Glucosamine results in decreased expression of PPM1A mRNA |
CTD |
PMID:17178593 |
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NCBI chr 6:91,439,094...91,486,139
Ensembl chr 6:91,438,834...91,480,697
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G |
Ppp1r15a |
protein phosphatase 1, regulatory subunit 15A |
decreases expression |
ISO |
Glucosamine results in decreased expression of PPP1R15A mRNA |
CTD |
PMID:17178593 |
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NCBI chr 1:96,000,053...96,003,128
Ensembl chr 1:96,000,058...96,003,171
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G |
Prc1 |
protein regulator of cytokinesis 1 |
decreases expression |
EXP |
Glucosamine results in decreased expression of PRC1 mRNA |
CTD |
PMID:17109745 |
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NCBI chr 1:134,250,086...134,271,765
Ensembl chr 1:134,250,081...134,271,765
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G |
Prkaa1 |
protein kinase AMP-activated catalytic subunit alpha 1 |
multiple interactions |
ISO |
PRKAA1 protein promotes the reaction [Glucosamine inhibits the reaction [INS protein results in increased phosphorylation of GSK3B protein]]; PRKAA1 protein promotes the reaction [NUS1 protein inhibits the reaction [Glucosamine inhibits the reaction [INS protein results in increased phosphorylation of GSK3B protein]]] |
CTD |
PMID:33812996 |
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NCBI chr 2:54,240,298...54,275,978
Ensembl chr 2:54,240,137...54,275,978
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G |
Psme3 |
proteasome activator subunit 3 |
decreases expression |
ISO |
Glucosamine results in decreased expression of PSME3 |
CTD |
PMID:21697645 |
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NCBI chr10:86,257,672...86,265,458
Ensembl chr10:86,257,668...86,333,804
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G |
Ptges |
prostaglandin E synthase |
multiple interactions |
ISO |
[Glucosamine co-treated with Chondroitin Sulfates co-treated with IL1B protein] results in decreased expression of PTGES protein; Glucosamine inhibits the reaction [IL1B results in increased expression of PTGES mRNA] |
CTD |
PMID:17605605 PMID:22089456 |
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NCBI chr 3:14,177,892...14,189,236
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G |
Ptgs2 |
prostaglandin-endoperoxide synthase 2 |
increases expression decreases expression multiple interactions decreases glycosylation |
ISO EXP |
Glucosamine analog results in increased expression of PTGS2 protein alternative form Glucosamine results in decreased expression of PTGS2 mRNA Glucosamine inhibits the reaction [Lipopolysaccharides results in increased expression of PTGS2 mRNA] Glucosamine analog inhibits the reaction [Lipopolysaccharides results in increased expression of PTGS2 mRNA]; Glucosamine analog inhibits the reaction [Lipopolysaccharides results in increased expression of PTGS2 protein]; Glucosamine inhibits the reaction [[Lipopolysaccharides results in increased expression of PTGS2 protein] which results in increased secretion of Dinoprostone]; Glucosamine inhibits the reaction [Lipopolysaccharides results in increased expression of PTGS2 mRNA]; Glucosamine inhibits the reaction [Lipopolysaccharides results in increased expression of PTGS2 protein] Glucosamine results in decreased glycosylation of PTGS2 protein [Glucosamine co-treated with Chondroitin Sulfates co-treated with IL1B protein] results in decreased expression of PTGS2 protein; Glucosamine inhibits the reaction [IL1B protein results in increased expression of PTGS2 mRNA]; Glucosamine inhibits the reaction [IL1B protein results in increased expression of PTGS2 protein]; Glucosamine promotes the reaction [Lipopolysaccharides results in increased expression of PTGS2 mRNA] |
CTD |
PMID:12681956 PMID:17440993 PMID:17605605 PMID:18205790 PMID:19656660 PMID:20737476 PMID:22089456 PMID:38437956 More...
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NCBI chr13:62,163,936...62,172,193
Ensembl chr13:62,163,932...62,172,188
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G |
Pttg1 |
PTTG1 regulator of sister chromatid separation, securin |
decreases expression |
EXP |
Glucosamine results in decreased expression of PTTG1 mRNA |
CTD |
PMID:17109745 |
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NCBI chr10:27,893,466...27,904,965
Ensembl chr10:27,893,689...27,904,837
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G |
Rab32 |
RAB32, member RAS oncogene family |
increases expression |
ISO |
Glucosamine results in increased expression of RAB32 mRNA |
CTD |
PMID:17178593 |
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NCBI chr 1:4,946,193...4,961,003
Ensembl chr 1:4,945,036...4,960,934
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G |
Racgap1 |
Rac GTPase-activating protein 1 |
decreases expression |
EXP |
Glucosamine results in decreased expression of RACGAP1 mRNA |
CTD |
PMID:17109745 |
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NCBI chr 7:130,750,936...130,780,891
Ensembl chr 7:130,750,936...130,780,831
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G |
Rbm39 |
RNA binding motif protein 39 |
decreases expression |
ISO |
Glucosamine results in decreased expression of RBM39 mRNA |
CTD |
PMID:17178593 |
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NCBI chr 3:144,662,998...144,696,222
Ensembl chr 3:144,663,001...144,696,213
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G |
Recql4 |
RecQ like helicase 4 |
increases expression |
ISO |
Glucosamine results in increased expression of RECQL4 mRNA |
CTD |
PMID:17178593 |
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NCBI chr 7:108,423,453...108,430,790
Ensembl chr 7:108,423,455...108,430,619
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Rela |
RELA proto-oncogene, NF-kB subunit |
multiple interactions decreases activity increases localization |
ISO EXP |
Alloxan inhibits the reaction [Glucosamine inhibits the reaction [TNF results in increased phosphorylation of RELA protein]]; Glucosamine analog inhibits the reaction [IL1B results in increased localization of RELA protein]; Glucosamine analog inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of RELA protein]; Glucosamine inhibits the reaction [Hydrogen Peroxide results in increased expression of and results in increased localization of RELA protein]; Glucosamine inhibits the reaction [IL1B protein results in increased localization of RELA protein]; Glucosamine inhibits the reaction [IL1B results in increased localization of RELA protein]; Glucosamine inhibits the reaction [NFKB1 results in increased degradation of RELA protein]; Glucosamine inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of RELA protein]; Glucosamine inhibits the reaction [TNF results in increased localization of RELA protein]; Glucosamine inhibits the reaction [TNF results in increased phosphorylation of RELA protein] Glucosamine results in decreased activity of RELA protein Glucosamine analog inhibits the reaction [Lipopolysaccharides results in increased expression of RELA protein]; Glucosamine analog inhibits the reaction [Lipopolysaccharides results in increased localization of RELA protein]; Glucosamine inhibits the reaction [Lipopolysaccharides promotes the reaction [RELA protein binds to NOS2 promoter]]; Glucosamine inhibits the reaction [Lipopolysaccharides results in increased expression of RELA mRNA]; Glucosamine inhibits the reaction [Lipopolysaccharides results in increased localization of RELA protein] Glucosamine results in increased localization of RELA protein |
CTD |
PMID:12681956 PMID:16431966 PMID:16822504 PMID:17238806 PMID:17498959 PMID:18036590 PMID:18080321 PMID:18205790 PMID:18340449 PMID:18786831 PMID:19020780 PMID:19375915 PMID:20307528 PMID:20737476 More...
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NCBI chr 1:202,925,001...202,935,484
Ensembl chr 1:202,924,945...202,935,484
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Relb |
RELB proto-oncogene, NF-kB subunit |
multiple interactions |
EXP |
Glucosamine inhibits the reaction [IL1B results in increased expression of RELB mRNA] |
CTD |
PMID:17109745 |
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NCBI chr 1:79,257,738...79,285,490
Ensembl chr 1:79,257,725...79,285,507
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Rhob |
ras homolog family member B |
increases expression |
ISO |
Glucosamine results in increased expression of RHOB mRNA |
CTD |
PMID:17178593 |
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NCBI chr 6:31,363,752...31,365,926
Ensembl chr 6:31,363,548...31,366,108
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Rhoc |
ras homolog family member C |
decreases expression |
ISO |
Glucosamine analog results in decreased expression of RHOC mRNA |
CTD |
PMID:16142878 |
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NCBI chr 2:192,287,065...192,293,292
Ensembl chr 2:192,287,130...192,295,306
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Rnd1 |
Rho family GTPase 1 |
multiple interactions decreases expression |
ISO |
Glucosamine analog inhibits the reaction [TNF results in increased expression of RND1 mRNA]; Glucosamine inhibits the reaction [TNF results in increased expression of RND1 mRNA] Glucosamine results in decreased expression of RND1 mRNA |
CTD |
PMID:17178593 PMID:18173918 |
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NCBI chr 7:129,821,311...129,828,385
Ensembl chr 7:129,821,311...129,828,399
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Rps6 |
ribosomal protein S6 |
decreases phosphorylation |
ISO |
Glucosamine results in decreased phosphorylation of RPS6 protein |
CTD |
PMID:19254699 |
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NCBI chr 5:101,371,716...101,374,576
Ensembl chr 5:101,371,136...101,374,602 Ensembl chr 5:101,371,136...101,374,602
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Rps6kb1 |
ribosomal protein S6 kinase B1 |
decreases phosphorylation |
ISO |
Glucosamine results in decreased phosphorylation of RPS6KB1 protein |
CTD |
PMID:19254699 |
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NCBI chr10:71,323,777...71,367,908
Ensembl chr10:71,323,777...71,367,908
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Runx2 |
RUNX family transcription factor 2 |
increases phosphorylation increases expression multiple interactions |
ISO |
Glucosamine analog results in increased phosphorylation of RUNX2 protein Glucosamine analog results in increased expression of RUNX2 mRNA 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide inhibits the reaction [Glucosamine analog results in increased phosphorylation of RUNX2 protein] |
CTD |
PMID:20458730 |
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NCBI chr 9:16,167,504...16,492,826
Ensembl chr 9:16,167,482...16,492,167
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Scd2 |
stearoyl-Coenzyme A desaturase 2 |
increases expression |
ISO |
Glucosamine results in increased expression of SCD2 mRNA |
CTD |
PMID:17178593 |
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NCBI chr 1:243,169,171...243,182,231
Ensembl chr 1:243,169,236...243,182,232
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Sdc2 |
syndecan 2 |
multiple interactions decreases expression |
EXP |
Glucosamine inhibits the reaction [IL1B results in decreased expression of SDC2 mRNA]; IL1B promotes the reaction [Glucosamine results in decreased expression of SDC2 mRNA] |
CTD |
PMID:17109745 |
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NCBI chr 7:64,127,185...64,239,885
Ensembl chr 7:64,127,110...64,241,081
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Sdc4 |
syndecan 4 |
multiple interactions decreases expression |
EXP |
Glucosamine inhibits the reaction [IL1B results in increased expression of SDC4 mRNA]; IL1B inhibits the reaction [Glucosamine results in decreased expression of SDC4 mRNA] |
CTD |
PMID:17109745 |
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NCBI chr 3:153,154,888...153,173,576
Ensembl chr 3:153,154,896...153,173,580
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Selenbp1 |
selenium binding protein 1 |
decreases expression |
EXP |
Glucosamine results in decreased expression of SELENBP1 mRNA |
CTD |
PMID:17109745 |
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NCBI chr 2:182,494,004...182,504,594
Ensembl chr 2:182,493,978...182,504,594
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G |
Serpinb2 |
serpin family B member 2 |
increases expression |
EXP |
Glucosamine results in increased expression of SERPINB2 mRNA |
CTD |
PMID:17109745 |
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NCBI chr13:23,537,312...23,551,823
Ensembl chr13:23,541,400...23,550,408
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Serpinh1 |
serpin family H member 1 |
increases expression |
ISO |
Glucosamine results in increased expression of SERPINH1 protein |
CTD |
PMID:16380481 |
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NCBI chr 1:153,643,500...153,650,853
Ensembl chr 1:153,643,510...153,650,801
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G |
Sfrp2 |
secreted frizzled-related protein 2 |
decreases expression |
EXP |
Glucosamine results in decreased expression of SFRP2 mRNA |
CTD |
PMID:17109745 |
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NCBI chr 2:169,089,517...169,097,064
Ensembl chr 2:169,089,517...169,097,063
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Sgk1 |
serum/glucocorticoid regulated kinase 1 |
decreases expression |
ISO |
Glucosamine results in decreased expression of SGK1 mRNA |
CTD |
PMID:17178593 |
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NCBI chr 1:22,980,257...23,098,122
Ensembl chr 1:22,980,261...23,098,283
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Shcbp1 |
SHC binding and spindle associated 1 |
decreases expression |
EXP |
Glucosamine results in decreased expression of SHCBP1 mRNA |
CTD |
PMID:17109745 |
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NCBI chr16:84,672,277...84,703,843
Ensembl chr16:84,672,321...84,703,844
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Slc17a1 |
solute carrier family 17 member 1 |
increases expression |
ISO |
Glucosamine results in increased expression of SLC17A1 mRNA |
CTD |
PMID:17178593 |
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NCBI chr17:41,219,461...41,255,199
Ensembl chr17:41,222,049...41,253,304
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Slc23a2 |
solute carrier family 23 member 2 |
increases expression |
EXP |
Glucosamine results in increased expression of SLC23A2 mRNA |
CTD |
PMID:17109745 |
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NCBI chr 3:119,302,651...119,395,289
Ensembl chr 3:119,302,666...119,460,343
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Slc2a2 |
solute carrier family 2 member 2 |
decreases expression |
EXP |
Glucosamine results in decreased expression of SLC2A2 mRNA |
CTD |
PMID:11893929 |
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NCBI chr 2:111,609,798...111,639,930
Ensembl chr 2:111,611,774...111,639,933
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Slc2a4 |
solute carrier family 2 member 4 |
multiple interactions decreases expression increases uptake |
ISO EXP |
4-phenylbutyric acid inhibits the reaction [Glucosamine results in decreased expression of SLC2A4 mRNA]; 4-phenylbutyric acid inhibits the reaction [Glucosamine results in decreased expression of SLC2A4 protein]; ATF6 mutant form inhibits the reaction [Glucosamine results in decreased expression of SLC2A4 mRNA]; ATF6 mutant form inhibits the reaction [Glucosamine results in decreased expression of SLC2A4 protein]; ursodoxicoltaurine inhibits the reaction [Glucosamine results in decreased expression of SLC2A4 mRNA]; ursodoxicoltaurine inhibits the reaction [Glucosamine results in decreased expression of SLC2A4 protein] Glucosamine results in decreased expression of SLC2A4 mRNA; Glucosamine results in decreased expression of SLC2A4 protein SLC2A4 protein results in increased uptake of Glucosamine Glucosamine inhibits the reaction [SLC2A4 protein results in increased uptake of Glucose]; Glucose inhibits the reaction [SLC2A4 protein results in increased uptake of Glucosamine] |
CTD |
PMID:19373748 PMID:20165829 |
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NCBI chr10:54,666,015...54,671,581
Ensembl chr10:54,666,015...54,671,565
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Slc2a6 |
solute carrier family 2 member 6 |
decreases expression |
ISO |
Glucosamine results in decreased expression of SLC2A6 mRNA |
CTD |
PMID:17178593 |
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NCBI chr 3:10,348,395...10,355,208
Ensembl chr 3:10,348,395...10,355,208
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Slc37a4 |
solute carrier family 37 member 4 |
increases expression |
ISO |
Glucosamine results in increased expression of SLC37A4 mRNA |
CTD |
PMID:17178593 |
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NCBI chr 8:44,723,216...44,729,301
Ensembl chr 8:44,723,339...44,729,301
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Slc4a4 |
solute carrier family 4 member 4 |
decreases expression |
EXP |
Glucosamine results in decreased expression of SLC4A4 mRNA |
CTD |
PMID:17109745 |
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NCBI chr14:18,841,289...19,293,297
Ensembl chr14:18,845,159...19,272,883
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Slc7a8 |
solute carrier family 7 member 8 |
increases expression multiple interactions |
EXP |
Glucosamine results in increased expression of SLC7A8 mRNA Glucosamine inhibits the reaction [IL1B results in increased expression of SLC7A8 mRNA]; IL1B inhibits the reaction [Glucosamine results in decreased expression of SLC7A8 mRNA] |
CTD |
PMID:17109745 |
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NCBI chr15:28,183,013...28,242,717
Ensembl chr15:28,183,015...28,242,717
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G |
Smad2 |
SMAD family member 2 |
multiple interactions increases phosphorylation |
ISO |
4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide inhibits the reaction [Glucosamine analog results in increased phosphorylation of SMAD2 protein] |
CTD |
PMID:20458730 |
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NCBI chr18:69,849,884...69,918,926
Ensembl chr18:69,850,377...69,912,323
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Smpd3 |
sphingomyelin phosphodiesterase 3 |
decreases expression |
EXP |
Glucosamine results in decreased expression of SMPD3 mRNA |
CTD |
PMID:17109745 |
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NCBI chr19:34,162,337...34,245,786
Ensembl chr19:34,162,341...34,245,749
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G |
Sox4 |
SRY-box transcription factor 4 |
multiple interactions decreases expression |
EXP |
Glucosamine inhibits the reaction [IL1B results in decreased expression of SOX4 mRNA] Glucosamine results in decreased expression of SOX4 mRNA |
CTD |
PMID:17109745 |
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NCBI chr17:35,667,809...35,672,515
Ensembl chr17:35,667,537...35,673,665
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G |
Srsf3 |
serine and arginine rich splicing factor 3 |
decreases expression |
ISO |
Glucosamine results in decreased expression of SRSF3 mRNA |
CTD |
PMID:17178593 |
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NCBI chr20:7,091,928...7,101,860
Ensembl chr20:7,091,910...7,101,078
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G |
St6gal1 |
ST6 beta-galactoside alpha-2,6-sialyltransferase 1 |
increases expression |
ISO |
Glucosamine results in increased expression of ST6GAL1 mRNA |
CTD |
PMID:17178593 |
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NCBI chr11:77,526,837...77,653,474
Ensembl chr11:77,526,837...77,653,310
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Stat1 |
signal transducer and activator of transcription 1 |
multiple interactions |
ISO |
Glucosamine inhibits the reaction [IFNG results in increased localization of STAT1 protein modified form]; Glucosamine inhibits the reaction [IFNG results in increased phosphorylation of and results in increased localization of STAT1 protein] |
CTD |
PMID:16431966 PMID:17238806 |
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NCBI chr 9:49,419,561...49,459,969
Ensembl chr 9:49,419,340...49,588,540
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Tacc3 |
transforming, acidic coiled-coil containing protein 3 |
decreases expression |
EXP |
Glucosamine results in decreased expression of TACC3 mRNA |
CTD |
PMID:17109745 |
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NCBI chr14:77,051,209...77,065,343
Ensembl chr14:77,051,215...77,065,219
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Testin |
testin gene |
decreases expression |
EXP |
Glucosamine results in decreased expression of TESTIN mRNA |
CTD |
PMID:17109745 |
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NCBI chr17:3,824,222...3,859,385
Ensembl chr17:3,846,899...3,859,385
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G |
Tgfa |
transforming growth factor alpha |
multiple interactions |
EXP |
[Glucose co-treated with Glucosamine] results in increased expression of TGFA protein; Glucosamine promotes the reaction [Glucose results in increased expression of TGFA mRNA] |
CTD |
PMID:1518840 |
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NCBI chr 4:118,618,043...118,700,897
Ensembl chr 4:118,618,269...118,700,894
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Tgfb1 |
transforming growth factor, beta 1 |
increases expression |
EXP |
Glucosamine analog results in increased expression of TGFB1 mRNA |
CTD |
PMID:21466783 |
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NCBI chr 1:81,196,532...81,212,848
Ensembl chr 1:81,196,532...81,212,847
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Tgfbr1 |
transforming growth factor, beta receptor 1 |
increases expression multiple interactions |
ISO |
Glucosamine analog results in increased expression of TGFBR1 protein 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide inhibits the reaction [Glucosamine analog results in increased expression of TGFBR1 protein] |
CTD |
PMID:20458730 |
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NCBI chr 5:61,653,773...61,710,777
Ensembl chr 5:61,653,233...61,710,777
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G |
Thbs4 |
thrombospondin 4 |
multiple interactions decreases expression |
EXP |
Glucosamine inhibits the reaction [IL1B results in decreased expression of THBS4 mRNA]; IL1B promotes the reaction [Glucosamine results in decreased expression of THBS4 mRNA] |
CTD |
PMID:17109745 |
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NCBI chr 2:23,983,158...24,025,289
Ensembl chr 2:23,983,158...24,026,313
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G |
Timp1 |
TIMP metallopeptidase inhibitor 1 |
multiple interactions increases expression |
EXP |
Glucosamine inhibits the reaction [IL1B results in increased expression of TIMP1 mRNA]; IL1B promotes the reaction [Glucosamine results in increased expression of TIMP1 mRNA] |
CTD |
PMID:17109745 |
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NCBI chr X:1,212,969...1,217,714
Ensembl chr X:1,212,972...1,217,664
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G |
Timp2 |
TIMP metallopeptidase inhibitor 2 |
affects expression multiple interactions |
EXP |
Glucosamine affects the expression of TIMP2 mRNA Glucosamine inhibits the reaction [IL1B results in decreased expression of TIMP2 mRNA] |
CTD |
PMID:17109745 |
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NCBI chr10:103,541,199...103,590,611
Ensembl chr10:103,531,505...103,590,611
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G |
Timp3 |
TIMP metallopeptidase inhibitor 3 |
multiple interactions increases expression |
ISO EXP |
[Glucosamine co-treated with Chondroitin Sulfates co-treated with IL1B protein] results in increased expression of TIMP3 mRNA Glucosamine results in increased expression of TIMP3 mRNA Glucosamine inhibits the reaction [IL1B results in decreased expression of TIMP3 mRNA]; IL1B affects the reaction [Glucosamine results in increased expression of TIMP3 mRNA] |
CTD |
PMID:17109745 PMID:17605605 |
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NCBI chr 7:17,520,827...17,571,850
Ensembl chr 7:17,521,919...17,571,839
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Tinag |
tubulointerstitial nephritis antigen |
increases expression |
ISO |
Glucosamine results in increased expression of TINAG mRNA |
CTD |
PMID:17178593 |
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NCBI chr 8:77,800,031...77,885,077
Ensembl chr 8:77,800,032...77,885,077
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G |
Tk1 |
thymidine kinase 1 |
decreases expression |
EXP |
Glucosamine results in decreased expression of TK1 mRNA |
CTD |
PMID:17109745 |
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NCBI chr10:103,034,755...103,046,125
Ensembl chr10:103,031,521...103,046,920
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Tlr1 |
toll-like receptor 1 |
increases expression |
ISO |
Glucosamine results in increased expression of TLR1 mRNA |
CTD |
PMID:17178593 |
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NCBI chr14:43,384,127...43,396,765
Ensembl chr14:43,384,932...43,397,125
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G |
Tnf |
tumor necrosis factor |
decreases secretion multiple interactions decreases expression |
ISO EXP |
Glucosamine results in decreased secretion of TNF protein Glucosamine inhibits the reaction [Lipopolysaccharides results in increased expression of TNF mRNA]; Glucosamine inhibits the reaction [Lipopolysaccharides results in increased expression of TNF protein]; Glucosamine inhibits the reaction [Lipopolysaccharides results in increased secretion of TNF protein] Glucosamine analog results in decreased expression of TNF mRNA; Glucosamine results in decreased expression of TNF mRNA Glucosamine analog inhibits the reaction [Lipopolysaccharides results in increased expression of and results in increased secretion of TNF protein]; Glucosamine analog inhibits the reaction [Lipopolysaccharides results in increased expression of TNF protein]; Glucosamine inhibits the reaction [Lipopolysaccharides results in increased expression of TNF mRNA] [Glucosamine co-treated with Chondroitin Sulfates] results in decreased expression of TNF; Alloxan inhibits the reaction [Glucosamine inhibits the reaction [TNF results in increased phosphorylation of RELA protein]]; Glucosamine analog inhibits the reaction [TNF results in increased expression of CUL2 mRNA]; Glucosamine analog inhibits the reaction [TNF results in increased expression of CXCL8 mRNA]; Glucosamine analog inhibits the reaction [TNF results in increased expression of GSPT1 mRNA]; Glucosamine analog inhibits the reaction [TNF results in increased expression of IL6 mRNA]; Glucosamine analog inhibits the reaction [TNF results in increased expression of RND1 mRNA]; Glucosamine analog inhibits the reaction [TNF results in increased expression of TNFRSF1A mRNA]; Glucosamine analog inhibits the reaction [TNF results in increased expression of TNFRSF1B mRNA]; Glucosamine analog inhibits the reaction [TNF results in increased expression of TRAF6 mRNA]; Glucosamine inhibits the reaction [[IL6 co-treated with TNF] results in increased expression of ICAM1 protein]; Glucosamine inhibits the reaction [IFNG promotes the reaction [TNF results in increased expression of ICAM1 protein]]; Glucosamine inhibits the reaction [IL1B promotes the reaction [TNF results in increased expression of ICAM1 protein]]; Glucosamine inhibits the reaction [TNF promotes the reaction [IFNG results in increased expression of ICAM1 protein]]; Glucosamine inhibits the reaction [TNF promotes the reaction [IL1B results in increased expression of ICAM1 protein]]; Glucosamine inhibits the reaction [TNF results in increased expression of CCL2 mRNA]; Glucosamine inhibits the reaction [TNF results in increased expression of CCL2 protein]; Glucosamine inhibits the reaction [TNF results in increased expression of CUL2 mRNA]; Glucosamine inhibits the reaction [TNF results in increased expression of CXCL8 mRNA]; Glucosamine inhibits the reaction [TNF results in increased expression of GSPT1 mRNA]; Glucosamine inhibits the reaction [TNF results in increased expression of ICAM1 mRNA]; Glucosamine inhibits the reaction [TNF results in increased expression of ICAM1 protein]; Glucosamine inhibits the reaction [TNF results in increased expression of IL6 mRNA]; Glucosamine inhibits the reaction [TNF results in increased expression of RND1 mRNA]; Glucosamine inhibits the reaction [TNF results in increased expression of TNFRSF1A mRNA]; Glucosamine inhibits the reaction [TNF results in increased expression of TNFRSF1B mRNA]; Glucosamine inhibits the reaction [TNF results in increased expression of TRAF6 mRNA]; Glucosamine inhibits the reaction [TNF results in increased localization of RELA protein]; Glucosamine inhibits the reaction [TNF results in increased phosphorylation of RELA protein]; Glucosamine promotes the reaction [Lipopolysaccharides results in increased expression of TNF mRNA] |
CTD |
PMID:14507305 PMID:16431966 PMID:16445576 PMID:16822504 PMID:17238806 PMID:18173918 PMID:18205790 PMID:18786831 PMID:19020780 PMID:19098112 PMID:20093129 PMID:20110869 PMID:20113495 PMID:20737476 PMID:38437956 More...
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NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629
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G |
Tnfaip6 |
TNF alpha induced protein 6 |
multiple interactions decreases expression |
EXP |
Glucosamine inhibits the reaction [IL1B results in increased expression of TNFAIP6 mRNA]; IL1B affects the reaction [Glucosamine results in decreased expression of TNFAIP6 mRNA] |
CTD |
PMID:17109745 |
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NCBI chr 3:36,502,250...36,521,652
Ensembl chr 3:36,502,188...36,521,649
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Tnfrsf11b |
TNF receptor superfamily member 11B |
multiple interactions |
ISO |
[Chondroitin Sulfates co-treated with Glucosamine co-treated with Cholecalciferol] results in increased expression of TNFRSF11B mRNA; [Chondroitin Sulfates co-treated with Glucosamine co-treated with Cholecalciferol] results in increased expression of TNFRSF11B protein; [Chondroitin Sulfates co-treated with Glucosamine] results in increased expression of TNFRSF11B mRNA; [Chondroitin Sulfates co-treated with Glucosamine] results in increased expression of TNFRSF11B protein |
CTD |
PMID:17996099 |
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NCBI chr 7:85,566,520...85,594,526
Ensembl chr 7:85,566,520...85,594,538
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Tnfrsf1a |
TNF receptor superfamily member 1A |
multiple interactions |
ISO |
Glucosamine analog inhibits the reaction [TNF results in increased expression of TNFRSF1A mRNA]; Glucosamine inhibits the reaction [TNF results in increased expression of TNFRSF1A mRNA] |
CTD |
PMID:18173918 |
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NCBI chr 4:158,150,815...158,163,592
Ensembl chr 4:158,150,820...158,163,591
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G |
Tnfrsf1b |
TNF receptor superfamily member 1B |
multiple interactions |
ISO |
Glucosamine analog inhibits the reaction [TNF results in increased expression of TNFRSF1B mRNA]; Glucosamine inhibits the reaction [TNF results in increased expression of TNFRSF1B mRNA] |
CTD |
PMID:18173918 |
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NCBI chr 5:157,070,642...157,104,216
Ensembl chr 5:157,070,642...157,104,206
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G |
Tnfsf11 |
TNF superfamily member 11 |
multiple interactions increases expression |
ISO |
[Chondroitin Sulfates co-treated with Glucosamine] inhibits the reaction [Cholecalciferol results in increased expression of TNFSF11 mRNA]; Chondroitin Sulfates inhibits the reaction [Glucosamine results in increased expression of TNFSF11 mRNA] |
CTD |
PMID:17996099 |
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NCBI chr15:53,673,850...53,705,325
Ensembl chr15:53,673,877...53,705,445
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G |
Tnk2 |
tyrosine kinase, non-receptor, 2 |
multiple interactions |
EXP |
Glucosamine inhibits the reaction [IL1B results in increased expression of TNK2 mRNA] |
CTD |
PMID:17109745 |
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NCBI chr11:68,114,725...68,154,254
Ensembl chr11:68,114,726...68,154,009
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G |
Top2a |
DNA topoisomerase II alpha |
decreases expression |
EXP |
Glucosamine results in decreased expression of TOP2A mRNA |
CTD |
PMID:17109745 |
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NCBI chr10:83,945,731...83,976,874
Ensembl chr10:83,945,735...83,976,874
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G |
Traf6 |
TNF receptor associated factor 6 |
multiple interactions |
ISO |
Glucosamine analog inhibits the reaction [TNF results in increased expression of TRAF6 mRNA]; Glucosamine inhibits the reaction [TNF results in increased expression of TRAF6 mRNA] |
CTD |
PMID:18173918 |
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NCBI chr 3:87,963,517...87,988,316
Ensembl chr 3:87,963,514...87,983,507
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G |
Trpv4 |
transient receptor potential cation channel, subfamily V, member 4 |
increases expression |
ISO |
Glucosamine results in increased expression of TRPV4 mRNA |
CTD |
PMID:17178593 |
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NCBI chr12:41,938,533...41,977,517
Ensembl chr12:41,938,560...41,977,517
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G |
Txn1 |
thioredoxin 1 |
decreases expression |
EXP ISO |
Glucosamine results in decreased expression of TXN1 protein |
CTD |
PMID:17178593 |
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NCBI chr 5:72,712,334...72,724,564
Ensembl chr 5:72,711,933...72,724,629
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G |
Txnip |
thioredoxin interacting protein |
increases expression multiple interactions |
EXP ISO |
Glucosamine results in increased expression of TXNIP protein Glucosamine results in increased expression of TXNIP mRNA; Glucosamine results in increased expression of TXNIP protein Glucosamine promotes the reaction [TXNIP results in increased abundance of Reactive Oxygen Species]; TXNIP promotes the reaction [Glucosamine results in increased expression of LAMB1 mRNA]; TXNIP promotes the reaction [Glucosamine results in increased expression of LAMC1 mRNA] |
CTD |
PMID:17178593 |
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NCBI chr 2:184,093,079...184,096,882
Ensembl chr 2:184,092,991...184,096,886
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G |
Ucp2 |
uncoupling protein 2 |
decreases expression |
EXP |
Glucosamine results in decreased expression of UCP2 mRNA |
CTD |
PMID:11893929 |
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NCBI chr 1:154,839,242...154,845,612
Ensembl chr 1:154,839,209...154,845,611
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G |
Uqcrh |
ubiquinol-cytochrome c reductase hinge protein |
increases expression |
ISO |
Glucosamine results in increased expression of UQCRH mRNA |
CTD |
PMID:17178593 |
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NCBI chr 5:129,545,978...129,554,173
Ensembl chr 5:129,545,984...129,554,242
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G |
Vamp1 |
vesicle-associated membrane protein 1 |
increases expression |
EXP |
Glucosamine results in increased expression of VAMP1 mRNA |
CTD |
PMID:17109745 |
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NCBI chr 4:158,012,634...158,019,350
Ensembl chr 4:158,012,663...158,019,349
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G |
Vcan |
versican |
multiple interactions decreases expression |
EXP |
Glucosamine inhibits the reaction [IL1B results in increased expression of VCAN mRNA]; IL1B affects the reaction [Glucosamine results in decreased expression of VCAN mRNA] |
CTD |
PMID:17109745 |
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NCBI chr 2:20,761,718...20,860,637
Ensembl chr 2:20,761,718...20,860,637
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G |
Vegfa |
vascular endothelial growth factor A |
multiple interactions increases expression decreases expression |
ISO EXP |
Glucosamine inhibits the reaction [Oxygen deficiency results in increased expression of VEGFA protein] Glucosamine results in increased expression of VEGFA protein Glucosamine results in decreased expression of VEGFA protein |
CTD |
PMID:16324875 PMID:19254699 |
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NCBI chr 9:14,955,300...14,970,641
Ensembl chr 9:14,955,300...14,970,641
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G |
Vegfd |
vascular endothelial growth factor D |
increases expression decreases expression |
ISO EXP |
Glucosamine results in increased expression of VEGFD mRNA Glucosamine results in decreased expression of VEGFD mRNA |
CTD |
PMID:17109745 PMID:17178593 |
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NCBI chr X:30,073,122...30,108,413
Ensembl chr X:30,074,163...30,108,295
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G |
Vnn1 |
vanin 1 |
increases expression |
ISO |
Glucosamine results in increased expression of VNN1 mRNA |
CTD |
PMID:17178593 |
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NCBI chr 1:21,537,084...21,547,395
Ensembl chr 1:21,537,094...21,547,395
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G |
Xbp1 |
X-box binding protein 1 |
multiple interactions increases splicing increases expression decreases splicing |
ISO EXP |
4-phenylbutyric acid inhibits the reaction [Glucosamine results in increased expression of XBP1 mRNA]; NUS1 protein inhibits the reaction [Glucosamine results in increased splicing of XBP1 mRNA]; ursodoxicoltaurine inhibits the reaction [Glucosamine results in increased expression of XBP1 mRNA] 4-methylumbelliferone 8-carbaldehyde affects the reaction [Glucosamine results in increased expression of XBP1 protein alternative form]; 4-methylumbelliferone 8-carbaldehyde inhibits the reaction [Glucosamine results in increased splicing of XBP1 mRNA]; 4-phenylbutyric acid inhibits the reaction [Glucosamine results in increased expression of XBP1 protein alternative form]; 4-phenylbutyric acid inhibits the reaction [Glucosamine results in increased splicing of XBP1 mRNA]; ERN1 protein affects the reaction [Glucosamine results in increased splicing of XBP1 mRNA] 4-phenylbutyric acid inhibits the reaction [Glucosamine results in increased expression of XBP1 mRNA]; ursodoxicoltaurine inhibits the reaction [Glucosamine results in increased expression of XBP1 mRNA] Glucosamine results in decreased splicing of XBP1 mRNA |
CTD |
PMID:19383982 PMID:20165829 PMID:30602124 PMID:33812996 |
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NCBI chr14:80,390,629...80,395,713
Ensembl chr14:80,390,643...80,395,693
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G |
Xdh |
xanthine dehydrogenase |
multiple interactions |
EXP |
[XDH protein co-treated with Hypoxanthine] inhibits the reaction [Glucosamine results in increased abundance of Proteoglycans]; [XDH protein co-treated with Hypoxanthine] inhibits the reaction [Glucosamine results in increased expression of B3GAT3 mRNA] |
CTD |
PMID:11801247 |
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NCBI chr 6:21,530,463...21,592,172
Ensembl chr 6:21,530,113...21,592,268
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G |
Zfp467 |
zinc finger protein 467 |
increases expression |
ISO |
Glucosamine results in increased expression of ZFP467 mRNA |
CTD |
PMID:17178593 |
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NCBI chr 4:77,385,752...77,394,709
Ensembl chr 4:77,385,758...77,392,229
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G |
A2m |
alpha-2-macroglobulin |
increases uptake multiple interactions |
ISO |
A2M protein modified form results in increased uptake of Deoxyglucose HSPA5 protein affects the reaction [A2M protein modified form results in increased uptake of Deoxyglucose] |
CTD |
PMID:25720493 |
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NCBI chr 4:154,897,770...154,947,787
Ensembl chr 4:154,897,877...154,947,786
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G |
Abcb1a |
ATP binding cassette subfamily B member 1A |
multiple interactions |
ISO |
Deoxyglucose inhibits the reaction [ABCB1 protein results in increased export of Diazinon] |
CTD |
PMID:16221533 |
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NCBI chr 4:25,357,467...25,529,941
Ensembl chr 4:25,158,362...25,442,709
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G |
Abcc9 |
ATP binding cassette subfamily C member 9 |
multiple interactions |
ISO |
[Oligomycins co-treated with Deoxyglucose] results in increased activity of [KCNJ11 protein binds to ABCC9 protein]; Glyburide inhibits the reaction [[Oligomycins co-treated with Deoxyglucose] results in increased activity of [KCNJ11 protein binds to ABCC9 protein]] |
CTD |
PMID:28842488 |
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NCBI chr 4:175,531,854...175,655,849
Ensembl chr 4:175,532,547...175,655,356
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G |
Abra |
actin-binding Rho activating protein |
multiple interactions increases uptake |
EXP |
CCG 1423 promotes the reaction [ABRA mutant form promotes the reaction [INS1 protein results in increased uptake of Deoxyglucose]]; CCG 1423 promotes the reaction [ABRA mutant form results in increased uptake of Deoxyglucose]; CCG 1423 promotes the reaction [INS1 protein promotes the reaction [ABRA mutant form results in increased uptake of Deoxyglucose]]; INS1 protein promotes the reaction [ABRA mutant form results in increased uptake of Deoxyglucose] |
CTD |
PMID:21393865 |
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NCBI chr 7:72,970,187...72,974,255
Ensembl chr 7:72,970,186...72,974,255
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G |
Adipoq |
adiponectin, C1Q and collagen domain containing |
increases uptake multiple interactions |
ISO |
ADIPOQ protein modified form results in increased uptake of Deoxyglucose Indinavir inhibits the reaction [ADIPOQ protein modified form results in increased uptake of Deoxyglucose] |
CTD |
PMID:29991592 |
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NCBI chr11:77,721,912...77,735,644
Ensembl chr11:77,721,912...77,735,564
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G |
Agrp |
agouti related neuropeptide |
increases expression |
EXP |
Deoxyglucose results in increased expression of AGRP mRNA |
CTD |
PMID:10683841 |
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NCBI chr19:33,447,992...33,481,602
Ensembl chr19:33,447,992...33,449,584
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G |
Ap5s1 |
adaptor related protein complex 5 subunit sigma 1 |
increases expression |
ISO |
Deoxyglucose results in increased expression of AP5S1 mRNA |
CTD |
PMID:33770205 |
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NCBI chr 3:118,429,618...118,432,929
Ensembl chr 3:118,429,637...118,432,926
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G |
App |
amyloid beta precursor protein |
multiple interactions |
ISO |
[Sodium Azide co-treated with Deoxyglucose] affects the cleavage of and affects the localization of APP protein |
CTD |
PMID:17405930 |
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NCBI chr11:24,019,774...24,236,584
Ensembl chr11:24,019,778...24,236,561
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G |
Atg3 |
autophagy related 3 |
multiple interactions |
ISO |
Deoxyglucose affects the reaction [demycarosyl-3D-digitoxosylmithramycin SK affects the expression of ATG3 mRNA] |
CTD |
PMID:26079942 |
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NCBI chr11:55,624,914...55,653,249
Ensembl chr11:55,624,917...55,653,224
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G |
Atg4b |
autophagy related 4B, cysteine peptidase |
multiple interactions |
ISO |
[demycarosyl-3D-digitoxosylmithramycin SK co-treated with Deoxyglucose] results in increased expression of ATG4B mRNA |
CTD |
PMID:26079942 |
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NCBI chr 9:94,282,417...94,314,109
Ensembl chr 9:94,282,509...94,314,103
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G |
Atg7 |
autophagy related 7 |
multiple interactions |
ISO |
ATG7 protein inhibits the reaction [Deoxyglucose results in increased cleavage of CASP3 protein]; ATG7 protein inhibits the reaction [Deoxyglucose results in increased expression of DDIT3 protein]; ATG7 protein inhibits the reaction [Deoxyglucose results in increased expression of HSPA5 protein]; ATG7 protein promotes the reaction [Deoxyglucose results in increased prenylation of MAP1LC3B protein] |
CTD |
PMID:20593179 |
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NCBI chr 4:147,718,663...147,925,656
Ensembl chr 4:147,718,752...147,925,593
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G |
Bax |
BCL2 associated X, apoptosis regulator |
multiple interactions decreases expression |
ISO |
Deoxyglucose promotes the reaction [arsenic trioxide results in increased localization of and results in increased activity of BAX protein]; Deoxyglucose results in increased localization of and results in increased activity of BAX protein Deoxyglucose results in decreased expression of BAX mRNA |
CTD |
PMID:23041229 PMID:26079942 |
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NCBI chr 1:95,940,001...95,945,407
Ensembl chr 1:95,938,808...95,945,368
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G |
Bcl2 |
BCL2, apoptosis regulator |
multiple interactions |
ISO |
Deoxyglucose affects the reaction [demycarosyl-3D-digitoxosylmithramycin SK affects the expression of BCL2 mRNA]; Deoxyglucose promotes the reaction [Silybin results in decreased expression of BCL2 protein] |
CTD |
PMID:26079942 PMID:34053323 |
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NCBI chr13:22,689,783...22,853,920
Ensembl chr13:22,684,989...22,853,743 Ensembl chr13:22,684,989...22,853,743
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G |
Bcl2l1 |
Bcl2-like 1 |
decreases response to substance |
ISO |
BCL2L1 protein results in decreased susceptibility to Deoxyglucose |
CTD |
PMID:10679475 |
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NCBI chr 3:141,253,508...141,304,582
Ensembl chr 3:141,253,523...141,303,479
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G |
Becn1 |
beclin 1 |
multiple interactions |
ISO |
[bafilomycin A co-treated with Deoxyglucose co-treated with demycarosyl-3D-digitoxosylmithramycin SK] results in decreased expression of BECN1 protein; [demycarosyl-3D-digitoxosylmithramycin SK co-treated with Deoxyglucose] results in increased expression of BECN1 mRNA |
CTD |
PMID:26079942 |
|
NCBI chr10:86,231,387...86,246,742
Ensembl chr10:86,231,388...86,246,742
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G |
Bid |
BH3 interacting domain death agonist |
multiple interactions |
ISO |
Deoxyglucose promotes the reaction [arsenic trioxide results in increased cleavage of and results in increased activity of BID protein]; Deoxyglucose results in increased cleavage of and results in increased activity of BID protein |
CTD |
PMID:23041229 |
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NCBI chr 4:154,113,198...154,136,353
Ensembl chr 4:154,113,198...154,134,720
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G |
Casp3 |
caspase 3 |
multiple interactions increases activity increases cleavage |
ISO EXP |
ATG7 protein inhibits the reaction [Deoxyglucose results in increased cleavage of CASP3 protein]; Deoxyglucose affects the reaction [TXNIP protein affects the reaction [Glycation End Products, Advanced results in increased activity of CASP3 protein]]; Deoxyglucose promotes the reaction [Arsenic Trioxide results in increased cleavage of and results in increased activity of CASP3 protein]; Deoxyglucose promotes the reaction [Silybin results in decreased expression of and results in increased cleavage of CASP3 protein]; Deoxyglucose results in increased cleavage of and results in increased activity of CASP3 protein Deoxyglucose promotes the reaction [Metformin inhibits the reaction [Arsenic Trioxide results in increased expression of CASP3 protein modified form]] Deoxyglucose results in increased activity of CASP3 protein Corticosterone inhibits the reaction [Deoxyglucose results in increased activity of CASP3 protein]; GPX4 protein inhibits the reaction [Deoxyglucose results in increased activity of CASP3 protein] |
CTD |
PMID:10506188 PMID:15755911 PMID:20593179 PMID:23041229 PMID:29095437 PMID:34053323 PMID:37632267 More...
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NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648
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G |
Casp9 |
caspase 9 |
multiple interactions |
ISO |
[Deoxyglucose co-treated with Cisplatin] results in increased activity of CASP9 protein; Deoxyglucose promotes the reaction [arsenic trioxide results in increased cleavage of and results in increased activity of CASP9 protein]; Deoxyglucose results in increased cleavage of and results in increased activity of CASP9 protein |
CTD |
PMID:20138251 PMID:23041229 |
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NCBI chr 5:154,108,872...154,126,628
Ensembl chr 5:154,109,046...154,126,626
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G |
Cdkn1a |
cyclin-dependent kinase inhibitor 1A |
multiple interactions |
ISO |
[demycarosyl-3D-digitoxosylmithramycin SK co-treated with Deoxyglucose] results in increased expression of CDKN1A mRNA |
CTD |
PMID:26079942 |
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NCBI chr20:7,149,177...7,159,727
Ensembl chr20:7,149,217...7,159,585
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G |
Cemip2 |
cell migration inducing hyaluronidase 2 |
decreases expression |
ISO |
Deoxyglucose results in decreased expression of CEMIP2 mRNA |
CTD |
PMID:33770205 |
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NCBI chr 1:219,330,295...219,407,760
Ensembl chr 1:219,337,985...219,407,760
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G |
Chrm3 |
cholinergic receptor, muscarinic 3 |
affects response to substance |
ISO |
CHRM3 protein affects the susceptibility to Deoxyglucose |
CTD |
PMID:14724830 |
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NCBI chr17:60,005,137...60,467,250
Ensembl chr17:60,005,202...60,467,278
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G |
Chuk |
component of inhibitor of nuclear factor kappa B kinase complex |
affects localization |
ISO |
Deoxyglucose analog affects the localization of CHUK protein |
CTD |
PMID:27931795 |
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NCBI chr 1:242,959,539...242,995,066
Ensembl chr 1:242,959,760...242,995,065
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G |
Ctsd |
cathepsin D |
increases expression |
EXP |
Deoxyglucose results in increased expression of CTSD protein |
CTD |
PMID:20026095 |
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NCBI chr 1:197,527,467...197,539,343
Ensembl chr 1:197,527,467...197,539,488
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G |
Cul7 |
cullin 7 |
multiple interactions |
ISO |
[INS1 protein co-treated with CUL7 mutant form] results in increased uptake of Deoxyglucose |
CTD |
PMID:24219910 |
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NCBI chr 9:14,319,102...14,333,035
Ensembl chr 9:14,319,108...14,332,741
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G |
Ddit3 |
DNA-damage inducible transcript 3 |
multiple interactions increases expression |
ISO |
ATG7 protein inhibits the reaction [Deoxyglucose results in increased expression of DDIT3 protein]; Mannose inhibits the reaction [Deoxyglucose results in increased expression of DDIT3 protein] |
CTD |
PMID:20593179 |
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NCBI chr 7:63,115,645...63,121,203
Ensembl chr 7:63,116,380...63,121,201
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G |
Egfr |
epidermal growth factor receptor |
multiple interactions increases import |
ISO |
AICA ribonucleotide inhibits the reaction [EGFR protein results in increased import of Deoxyglucose] EGFR protein mutant form results in increased import of Deoxyglucose |
CTD |
PMID:19625624 |
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NCBI chr14:91,176,979...91,349,722
Ensembl chr14:91,177,067...91,344,382
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G |
Eif4ebp1 |
eukaryotic translation initiation factor 4E binding protein 1 |
multiple interactions |
ISO |
Deoxyglucose results in decreased phosphorylation of and results in increased expression of EIF4EBP1 protein |
CTD |
PMID:23363784 |
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NCBI chr16:64,792,595...64,805,984
Ensembl chr16:64,790,226...64,805,984
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G |
Erbb2 |
erb-b2 receptor tyrosine kinase 2 |
multiple interactions |
ISO |
[Deoxyglucose co-treated with Quercetin] results in increased ubiquitination of ERBB2 protein; Deoxyglucose inhibits the reaction [Quercetin promotes the reaction [ERBB2 protein binds to HSP90AA1 protein]] |
CTD |
PMID:18655187 |
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NCBI chr10:83,411,197...83,435,078
Ensembl chr10:83,411,313...83,435,078
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G |
Errfi1 |
ERBB receptor feedback inhibitor 1 |
decreases expression |
ISO |
Deoxyglucose results in decreased expression of ERRFI1 mRNA |
CTD |
PMID:33770205 |
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NCBI chr 5:161,323,981...161,337,289
Ensembl chr 5:161,323,998...161,337,282
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G |
Fam117a |
family with sequence similarity 117, member A |
decreases expression |
ISO |
Deoxyglucose results in decreased expression of FAM117A mRNA |
CTD |
PMID:33770205 |
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NCBI chr10:80,281,411...80,325,345
Ensembl chr10:80,281,408...80,325,343
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G |
Fxyd2 |
FXYD domain-containing ion transport regulator 2 |
multiple interactions increases transport |
ISO |
Calcium inhibits the reaction [FXYD2 protein results in increased transport of Deoxyglucose] |
CTD |
PMID:11533133 |
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NCBI chr 8:45,712,901...45,720,032
Ensembl chr 8:45,712,903...45,720,203
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G |
G3bp1 |
G3BP stress granule assembly factor 1 |
multiple interactions |
ISO |
Deoxyglucose inhibits the reaction [G3BP1 protein results in increased abundance of Lactic Acid]; Deoxyglucose inhibits the reaction [G3BP1 protein results in increased expression of HK2 protein]; Deoxyglucose inhibits the reaction [G3BP1 protein results in increased expression of LDHA protein]; Deoxyglucose inhibits the reaction [G3BP1 protein results in increased expression of PKM protein]; Deoxyglucose inhibits the reaction [G3BP1 protein results in increased uptake of Glucose] |
CTD |
PMID:35945655 |
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NCBI chr10:39,586,864...39,620,268
Ensembl chr10:39,586,864...39,620,268
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G |
Galr1 |
galanin receptor 1 |
increases expression |
EXP |
Deoxyglucose results in increased expression of GALR1 mRNA |
CTD |
PMID:9858361 PMID:9928191 |
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NCBI chr18:75,772,021...75,787,577
Ensembl chr18:75,772,023...75,787,577
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G |
Gcg |
glucagon |
multiple interactions increases secretion |
ISO |
Capsaicin inhibits the reaction [Deoxyglucose results in increased secretion of GCG protein] |
CTD |
PMID:1378463 |
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NCBI chr 3:47,113,914...47,122,958
Ensembl chr 3:47,113,914...47,122,929
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G |
Gpx4 |
glutathione peroxidase 4 |
multiple interactions |
EXP |
GPX4 protein inhibits the reaction [Deoxyglucose results in increased activity of CASP3 protein] |
CTD |
PMID:10506188 |
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NCBI chr 7:9,650,186...9,652,982
Ensembl chr 7:9,650,185...9,652,982
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G |
Gsk3b |
glycogen synthase kinase 3 beta |
multiple interactions |
ISO |
Deoxyglucose inhibits the reaction [arsenic trioxide results in increased phosphorylation of GSK3B protein]; Deoxyglucose inhibits the reaction [Fenretinide results in increased phosphorylation of GSK3B protein] |
CTD |
PMID:25246272 |
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NCBI chr11:62,498,997...62,648,665
Ensembl chr11:62,504,316...62,648,646
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G |
H2ax |
H2A.X variant histone |
decreases expression |
ISO |
Deoxyglucose results in decreased expression of H2AX protein |
CTD |
PMID:23363784 |
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NCBI chr 8:44,671,907...44,673,262
Ensembl chr 8:44,671,786...44,673,239
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G |
Hk2 |
hexokinase 2 |
multiple interactions |
ISO |
[Lactic Acid co-treated with Deoxyglucose] inhibits the reaction [[Cadmium Chloride results in increased abundance of Cadmium] which results in increased expression of HK2 protein]; Deoxyglucose inhibits the reaction [[Cadmium Chloride results in increased abundance of Cadmium] which results in increased expression of HK2 protein]; Deoxyglucose inhibits the reaction [G3BP1 protein results in increased expression of HK2 protein]; Deoxyglucose inhibits the reaction [HMGA2 protein results in increased expression of HK2 protein]; Deoxyglucose results in decreased expression of and results in decreased activity of HK2 protein |
CTD |
PMID:32619556 PMID:34481905 PMID:35945655 PMID:36336208 |
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NCBI chr 4:115,234,509...115,283,530
Ensembl chr 4:115,234,509...115,283,530
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G |
Hmga2 |
high mobility group AT-hook 2 |
multiple interactions |
ISO |
Deoxyglucose inhibits the reaction [HMGA2 protein results in decreased expression of COX4 protein]; Deoxyglucose inhibits the reaction [HMGA2 protein results in decreased expression of ND1 protein]; Deoxyglucose inhibits the reaction [HMGA2 protein results in increased expression of HK2 protein]; Deoxyglucose inhibits the reaction [HMGA2 protein results in increased expression of MMP2 protein]; Deoxyglucose inhibits the reaction [HMGA2 protein results in increased expression of MMP9 protein] |
CTD |
PMID:34481905 |
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NCBI chr 7:55,877,145...55,998,813
Ensembl chr 7:55,880,112...55,994,784
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G |
Hmox1 |
heme oxygenase 1 |
multiple interactions |
ISO |
Deoxyglucose inhibits the reaction [arsenic trioxide results in increased expression of HMOX1 protein]; Deoxyglucose inhibits the reaction [Fenretinide results in increased expression of HMOX1 protein] |
CTD |
PMID:25246272 |
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NCBI chr19:13,466,287...13,474,082
Ensembl chr19:13,467,244...13,474,079
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G |
Hsp90aa1 |
heat shock protein 90 alpha family class A member 1 |
multiple interactions |
ISO |
Deoxyglucose inhibits the reaction [Quercetin promotes the reaction [ERBB2 protein binds to HSP90AA1 protein]] |
CTD |
PMID:18655187 |
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NCBI chr 6:129,702,376...129,707,907
Ensembl chr 6:129,702,383...129,707,268
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G |
Hsp90b1 |
heat shock protein 90 beta family member 1 |
increases expression multiple interactions |
ISO |
Deoxyglucose results in increased expression of HSP90B1 protein 4-Quinolones analog inhibits the reaction [Deoxyglucose results in increased expression of HSP90B1 protein] |
CTD |
PMID:31022492 |
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NCBI chr 7:21,110,431...21,124,762
Ensembl chr 7:21,110,457...21,124,788
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G |
Hspa5 |
heat shock protein family A (Hsp70) member 5 |
multiple interactions increases expression |
ISO |
4-Quinolones analog inhibits the reaction [Deoxyglucose results in increased expression of HSPA5 mRNA]; 4-Quinolones analog inhibits the reaction [Deoxyglucose results in increased expression of HSPA5 protein]; ATG7 protein inhibits the reaction [Deoxyglucose results in increased expression of HSPA5 protein]; HSPA5 protein affects the reaction [A2M protein modified form results in increased uptake of Deoxyglucose]; HSPA5 protein affects the reaction [INS protein results in increased uptake of Deoxyglucose]; Mannose inhibits the reaction [Deoxyglucose results in increased expression of HSPA5 protein]; Oxygen deficiency inhibits the reaction [Deoxyglucose results in increased expression of HSPA5 protein] Deoxyglucose results in increased expression of HSPA5 mRNA; Deoxyglucose results in increased expression of HSPA5 protein |
CTD |
PMID:20593179 PMID:25720493 PMID:31022492 |
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NCBI chr 3:18,055,507...18,059,969
Ensembl chr 3:18,055,405...18,059,891
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G |
Htra2 |
HtrA serine peptidase 2 |
multiple interactions decreases localization |
ISO |
Deoxyglucose promotes the reaction [arsenic trioxide results in decreased localization of HTRA2 protein] Deoxyglucose results in decreased localization of HTRA2 protein |
CTD |
PMID:23041229 |
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NCBI chr 4:115,556,914...115,560,202
Ensembl chr 4:115,556,916...115,560,095
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G |
Igf1r |
insulin-like growth factor 1 receptor |
multiple interactions |
ISO |
Deoxyglucose results in increased phosphorylation of and results in increased activity of IGF1R protein |
CTD |
PMID:23041229 |
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NCBI chr 1:121,549,831...121,838,548
Ensembl chr 1:121,550,743...121,831,777
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G |
Il1b |
interleukin 1 beta |
decreases response to substance multiple interactions |
ISO |
Deoxyglucose results in decreased susceptibility to IL1B protein Deoxyglucose inhibits the reaction [bisphenol F results in increased secretion of IL1B protein] Deoxyglucose inhibits the reaction [IL1B protein results in increased expression of MMP13 protein] |
CTD |
PMID:21211511 PMID:34147605 |
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NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415
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G |
Il6 |
interleukin 6 |
multiple interactions |
ISO |
Deoxyglucose inhibits the reaction [bisphenol F results in increased secretion of IL6 protein] |
CTD |
PMID:34147605 |
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NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178
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G |
Ins1 |
insulin 1 |
multiple interactions increases uptake increases transport increases secretion affects transport |
EXP ISO |
4-phenylbutyric acid inhibits the reaction [Glucosamine inhibits the reaction [INS1 results in increased uptake of Deoxyglucose]]; CCG 1423 promotes the reaction [ABRA mutant form promotes the reaction [INS1 protein results in increased uptake of Deoxyglucose]]; CCG 1423 promotes the reaction [INS1 protein promotes the reaction [ABRA mutant form results in increased uptake of Deoxyglucose]]; CCG 1423 promotes the reaction [INS1 protein results in increased uptake of Deoxyglucose]; Diethylhexyl Phthalate inhibits the reaction [INS1 protein results in increased uptake of Deoxyglucose]; Glucosamine inhibits the reaction [INS1 protein results in increased uptake of Deoxyglucose]; Glucosamine inhibits the reaction [INS1 results in increased uptake of Deoxyglucose]; Glucose inhibits the reaction [INS1 protein results in increased uptake of Deoxyglucose]; glyceryl 2-arachidonate promotes the reaction [INS1 protein results in increased uptake of Deoxyglucose]; INS1 protein promotes the reaction [ABRA mutant form results in increased uptake of Deoxyglucose]; INS1 protein promotes the reaction [CCG 1423 results in increased uptake of Deoxyglucose]; mono-(2-ethylhexyl)phthalate inhibits the reaction [INS1 protein results in increased uptake of Deoxyglucose]; N-(3-methoxyphenyl)-4-chlorocinnamanilide inhibits the reaction [glyceryl 2-arachidonate promotes the reaction [INS1 protein results in increased uptake of Deoxyglucose]]; oxophenylarsine inhibits the reaction [INS1 protein results in increased uptake of Deoxyglucose]; Palmitic Acid inhibits the reaction [INS1 protein results in increased uptake of Deoxyglucose]; Quercetin inhibits the reaction [Palmitic Acid inhibits the reaction [INS1 protein results in increased uptake of Deoxyglucose]]; Quercetin inhibits the reaction [TNF protein inhibits the reaction [INS1 protein results in increased uptake of Deoxyglucose]]; Quercetin promotes the reaction [INS1 protein results in increased uptake of Deoxyglucose]; Raffinose promotes the reaction [INS1 protein results in increased uptake of Deoxyglucose]; SLC2A4 promotes the reaction [INS1 protein results in increased uptake of Deoxyglucose]; TNF protein inhibits the reaction [INS1 protein results in increased uptake of Deoxyglucose]; ursodoxicoltaurine inhibits the reaction [Glucosamine inhibits the reaction [INS1 results in increased uptake of Deoxyglucose]] [INS1 protein co-treated with CUL7 mutant form] results in increased uptake of Deoxyglucose; acetylaminophenylarsine oxide inhibits the reaction [INS1 protein results in increased transport of Deoxyglucose]; Apigenin inhibits the reaction [INS1 protein results in increased uptake of Deoxyglucose]; Dimercaprol inhibits the reaction [oxophenylarsine inhibits the reaction [INS1 protein results in increased transport of Deoxyglucose]]; Dimercaprol inhibits the reaction [oxophenylarsine inhibits the reaction [INS1 protein results in increased uptake of Deoxyglucose]]; Dimercaprol inhibits the reaction [p-aminophenylarsine oxide inhibits the reaction [INS1 protein results in increased transport of Deoxyglucose]]; dorsomorphin inhibits the reaction [Quercetin inhibits the reaction [INS1 protein results in increased uptake of Deoxyglucose]]; epigallocatechin gallate inhibits the reaction [INS1 protein results in increased uptake of Deoxyglucose]; fisetin inhibits the reaction [INS1 protein results in increased uptake of Deoxyglucose]; Genistein inhibits the reaction [INS1 protein results in increased uptake of Deoxyglucose]; Genistein inhibits the reaction [Raffinose promotes the reaction [INS1 protein results in increased uptake of Deoxyglucose]]; kaempferol inhibits the reaction [INS1 protein results in increased uptake of Deoxyglucose]; Luteolin inhibits the reaction [INS1 protein results in increased uptake of Deoxyglucose]; oxophenylarsine inhibits the reaction [INS1 protein results in increased transport of Deoxyglucose]; oxophenylarsine inhibits the reaction [INS1 protein results in increased uptake of Deoxyglucose]; p-aminophenylarsine oxide inhibits the reaction [INS1 protein results in increased transport of Deoxyglucose]; Quercetin inhibits the reaction [INS1 protein results in increased uptake of Deoxyglucose]; Quercetin inhibits the reaction [TNF protein inhibits the reaction [INS1 protein results in increased uptake of Deoxyglucose]]; Raffinose promotes the reaction [INS1 protein results in increased uptake of Deoxyglucose]; Ro 31-8220 inhibits the reaction [INS1 protein results in increased uptake of Deoxyglucose]; Silybin inhibits the reaction [INS1 protein results in increased uptake of Deoxyglucose]; theaflavin inhibits the reaction [INS1 protein results in increased uptake of Deoxyglucose]; TNF protein inhibits the reaction [INS1 protein results in increased uptake of Deoxyglucose]; tyrphostin 25 inhibits the reaction [INS1 protein results in increased uptake of Deoxyglucose]; Wortmannin inhibits the reaction [Raffinose promotes the reaction [INS1 protein results in increased uptake of Deoxyglucose]] INS1 protein results in increased uptake of Deoxyglucose; INS1 results in increased uptake of Deoxyglucose Deoxyglucose results in increased secretion of INS1 protein INS1 protein affects the transport of Deoxyglucose |
CTD |
PMID:1378463 PMID:1536656 PMID:1847587 PMID:1918056 PMID:2202293 PMID:2877896 PMID:3882699 PMID:9453242 PMID:14511371 PMID:18591783 PMID:20165829 PMID:20206685 PMID:21393865 PMID:22713545 PMID:23439570 PMID:24219910 PMID:24287560 PMID:24343960 PMID:26627467 PMID:28298333 PMID:28526321 PMID:29458019 PMID:31408376 More...
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NCBI chr 1:251,244,973...251,245,540
Ensembl chr 1:251,244,973...251,245,536
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G |
Ins2 |
insulin 2 |
increases uptake multiple interactions |
ISO |
INS protein results in increased uptake of Deoxyglucose; INS results in increased uptake of Deoxyglucose METRNL protein inhibits the reaction [INS protein results in increased uptake of Deoxyglucose]; PPARA protein promotes the reaction [GW 7647 promotes the reaction [INS protein results in increased uptake of Deoxyglucose]] 3,3',4,5'-tetrahydroxystilbene inhibits the reaction [Palmitic Acid inhibits the reaction [INS protein results in increased uptake of Deoxyglucose]]; 4-phenylbutyric acid inhibits the reaction [Glucosamine inhibits the reaction [INS results in increased uptake of Deoxyglucose]]; Glucosamine inhibits the reaction [INS results in increased uptake of Deoxyglucose]; GW 7647 promotes the reaction [INS protein results in increased uptake of Deoxyglucose]; HSPA5 protein affects the reaction [INS protein results in increased uptake of Deoxyglucose]; Palmitates inhibits the reaction [INS protein results in increased uptake of Deoxyglucose]; Palmitic Acid inhibits the reaction [INS protein results in increased uptake of Deoxyglucose]; SLC2A1 protein inhibits the reaction [INS protein results in increased uptake of Deoxyglucose]; tin protoporphyrin IX inhibits the reaction [3,3',4,5'-tetrahydroxystilbene inhibits the reaction [Palmitic Acid inhibits the reaction [INS protein results in increased uptake of Deoxyglucose]]]; TNF protein inhibits the reaction [INS protein results in increased uptake of Deoxyglucose]; Troglitazone inhibits the reaction [TNF protein inhibits the reaction [INS protein results in increased uptake of Deoxyglucose]]; ursodoxicoltaurine inhibits the reaction [Glucosamine inhibits the reaction [INS results in increased uptake of Deoxyglucose]] |
CTD |
PMID:2173694 PMID:16483873 PMID:20165829 PMID:21324916 PMID:25720493 PMID:25815690 PMID:30213948 PMID:31877369 More...
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NCBI chr 1:197,843,277...197,992,522
Ensembl chr 1:197,843,281...197,864,775
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G |
Itgb1 |
integrin subunit beta 1 |
decreases expression |
ISO |
Deoxyglucose analog results in decreased expression of ITGB1 protein |
CTD |
PMID:27931795 |
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NCBI chr19:56,705,123...56,753,199
Ensembl chr19:56,705,171...56,753,195
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G |
Jade2 |
jade family PHD finger 2 |
increases expression |
ISO |
Deoxyglucose results in increased expression of JADE2 mRNA |
CTD |
PMID:33770205 |
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NCBI chr10:36,075,239...36,124,210
Ensembl chr10:36,078,917...36,116,984
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G |
Kcnh2 |
potassium voltage-gated channel subfamily H member 2 |
multiple interactions decreases activity |
ISO |
[Deoxyglucose co-treated with Glucose deficiency] results in decreased activity of KCNH2 protein; Deoxyglucose inhibits the reaction [Glucose results in decreased activity of KCNH2 protein]; Deoxyglucose promotes the reaction [Glucose deficiency results in decreased activity of KCNH2 protein]; Pyruvic Acid inhibits the reaction [[Deoxyglucose co-treated with Glucose deficiency] results in decreased activity of KCNH2 protein] Deoxyglucose results in decreased activity of KCNH2 protein |
CTD |
PMID:12531891 |
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NCBI chr 4:10,826,834...10,859,009
Ensembl chr 4:10,826,928...10,859,008
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G |
Kcnj11 |
potassium inwardly-rectifying channel, subfamily J, member 11 |
multiple interactions |
ISO |
[Oligomycins co-treated with Deoxyglucose] results in increased activity of [KCNJ11 protein binds to ABCC9 protein]; Glyburide inhibits the reaction [[Oligomycins co-treated with Deoxyglucose] results in increased activity of [KCNJ11 protein binds to ABCC9 protein]] |
CTD |
PMID:28842488 |
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NCBI chr 1:96,591,048...96,594,574
Ensembl chr 1:96,591,049...96,594,082
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G |
Klhl42 |
kelch-like family, member 42 |
increases expression |
ISO |
Deoxyglucose results in increased expression of KLHL42 mRNA |
CTD |
PMID:33770205 |
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NCBI chr 4:179,999,655...180,027,283
Ensembl chr 4:180,004,580...180,027,283
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G |
Ldha |
lactate dehydrogenase A |
multiple interactions |
ISO |
Deoxyglucose inhibits the reaction [G3BP1 protein results in increased expression of LDHA protein] |
CTD |
PMID:35945655 |
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NCBI chr 1:97,371,823...97,381,247
Ensembl chr 1:97,366,021...97,433,472
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G |
Lep |
leptin |
multiple interactions decreases secretion |
EXP |
[Deoxyglucose results in decreased abundance of Adenosine Triphosphate] which results in decreased secretion of LEP protein Deoxyglucose results in decreased secretion of LEP protein |
CTD |
PMID:10780946 |
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NCBI chr 4:57,661,127...57,675,262
Ensembl chr 4:57,661,131...57,675,262
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G |
Liph |
lipase H |
decreases expression |
ISO |
Deoxyglucose results in decreased expression of LIPH mRNA |
CTD |
PMID:33770205 |
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NCBI chr11:79,032,229...79,081,625
Ensembl chr11:79,033,312...79,081,625
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G |
Map1lc3a |
microtubule-associated protein 1 light chain 3 alpha |
multiple interactions |
ISO |
Deoxyglucose affects the reaction [demycarosyl-3D-digitoxosylmithramycin SK affects the expression of MAP1LC3A mRNA] |
CTD |
PMID:26079942 |
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NCBI chr 3:143,783,024...143,784,670
Ensembl chr 3:143,783,024...143,784,670
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G |
Map1lc3b |
microtubule-associated protein 1 light chain 3 beta |
multiple interactions increases prenylation |
ISO |
ATG7 protein promotes the reaction [Deoxyglucose results in increased prenylation of MAP1LC3B protein]; Mannose inhibits the reaction [Deoxyglucose results in increased prenylation of MAP1LC3B protein]; Oxygen deficiency inhibits the reaction [Deoxyglucose results in increased prenylation of MAP1LC3B protein] |
CTD |
PMID:20593179 |
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NCBI chr19:49,665,795...49,673,655
Ensembl chr19:49,665,791...49,677,690
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G |
Mapk1 |
mitogen activated protein kinase 1 |
multiple interactions |
ISO |
arsenic trioxide inhibits the reaction [Deoxyglucose results in increased phosphorylation of and results in increased activity of MAPK1 protein]; Deoxyglucose results in increased phosphorylation of and results in increased activity of MAPK1 protein; PQ 401 inhibits the reaction [Deoxyglucose results in increased phosphorylation of and results in increased activity of MAPK1 protein]; U 0126 inhibits the reaction [Deoxyglucose results in increased phosphorylation of and results in increased activity of MAPK1 protein] |
CTD |
PMID:23041229 |
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NCBI chr11:83,957,813...84,023,629
Ensembl chr11:83,957,813...84,023,616
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G |
Mapk3 |
mitogen activated protein kinase 3 |
multiple interactions |
EXP ISO |
MAPK3 protein affects the reaction [AICA ribonucleotide results in increased uptake of Deoxyglucose] Arsenic Trioxide inhibits the reaction [Deoxyglucose results in increased phosphorylation of and results in increased activity of MAPK3 protein]; Deoxyglucose results in increased phosphorylation of and results in increased activity of MAPK3 protein; PQ 401 inhibits the reaction [Deoxyglucose results in increased phosphorylation of and results in increased activity of MAPK3 protein]; U 0126 inhibits the reaction [Deoxyglucose results in increased phosphorylation of and results in increased activity of MAPK3 protein] |
CTD |
PMID:11978788 PMID:23041229 |
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NCBI chr 1:181,366,646...181,372,863
Ensembl chr 1:181,366,637...181,372,863
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G |
Mepce |
methylphosphate capping enzyme |
increases expression |
ISO |
Deoxyglucose results in increased expression of MEPCE mRNA |
CTD |
PMID:33770205 |
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NCBI chr12:18,911,796...18,916,515
Ensembl chr12:18,911,796...18,916,514
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G |
Metrnl |
meteorin-like, glial cell differentiation regulator |
multiple interactions |
ISO |
METRNL protein inhibits the reaction [INS protein results in increased uptake of Deoxyglucose] |
CTD |
PMID:30213948 |
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NCBI chr10:106,963,880...106,977,875
Ensembl chr10:106,963,880...106,977,869
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G |
Mmp13 |
matrix metallopeptidase 13 |
multiple interactions decreases expression |
ISO |
Deoxyglucose inhibits the reaction [IL1B protein results in increased expression of MMP13 protein]; Deoxyglucose inhibits the reaction [TNF protein results in increased expression of MMP13 protein] Deoxyglucose analog results in decreased expression of MMP13 protein |
CTD |
PMID:21211511 PMID:27931795 |
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NCBI chr 8:4,497,960...4,508,239
Ensembl chr 8:4,497,960...4,508,239
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G |
Mmp2 |
matrix metallopeptidase 2 |
multiple interactions |
ISO |
Deoxyglucose inhibits the reaction [[Cadmium Chloride results in increased abundance of Cadmium] which results in increased expression of MMP2 protein]; Deoxyglucose inhibits the reaction [HMGA2 protein results in increased expression of MMP2 protein] |
CTD |
PMID:34481905 |
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NCBI chr19:14,154,657...14,182,870
Ensembl chr19:14,154,657...14,182,870
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G |
Mmp9 |
matrix metallopeptidase 9 |
decreases expression multiple interactions |
ISO |
Deoxyglucose analog results in decreased expression of MMP9 protein Deoxyglucose inhibits the reaction [[Cadmium Chloride results in increased abundance of Cadmium] which results in increased expression of MMP9 protein]; Deoxyglucose inhibits the reaction [HMGA2 protein results in increased expression of MMP9 protein] |
CTD |
PMID:27931795 PMID:34481905 |
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NCBI chr 3:153,684,158...153,692,118
Ensembl chr 3:153,683,858...153,692,120
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G |
Mt-nd1 |
mitochondrially encoded NADH:ubiquinone oxidoreductase core subunit 1 |
multiple interactions |
ISO |
Deoxyglucose inhibits the reaction [Carbonyl Cyanide m-Chlorophenyl Hydrazone results in decreased expression of ND1 protein]; Deoxyglucose inhibits the reaction [HMGA2 protein results in decreased expression of ND1 protein] |
CTD |
PMID:34481905 |
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NCBI chr MT:2,740...3,694 NCBI chr MT:2,740...3,694 NCBI chr MT:2,740...3,694 NCBI chr MT:2,740...3,694 NCBI chr MT:2,740...3,694 NCBI chr MT:2,740...3,694 NCBI chr MT:2,740...3,694 NCBI chr MT:2,740...3,694 NCBI chr MT:2,740...3,694
Ensembl chr MT:2,740...3,694
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G |
Mtor |
mechanistic target of rapamycin kinase |
multiple interactions |
ISO |
Deoxyglucose results in decreased phosphorylation of and results in increased expression of MTOR protein; Deoxyglucose results in increased phosphorylation of and results in increased activity of MTOR protein |
CTD |
PMID:23041229 PMID:23363784 |
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NCBI chr 5:158,884,856...158,994,311
Ensembl chr 5:158,884,804...158,994,311
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G |
Mxi1 |
MAX interactor 1, dimerization protein |
decreases expression |
ISO |
Deoxyglucose results in decreased expression of MXI1 mRNA |
CTD |
PMID:33770205 |
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NCBI chr 1:252,323,915...252,383,682
Ensembl chr 1:252,323,303...252,383,681
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G |
Myo1e |
myosin IE |
decreases expression |
ISO |
Deoxyglucose results in decreased expression of MYO1E mRNA |
CTD |
PMID:33770205 |
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NCBI chr 8:70,887,934...71,080,180
Ensembl chr 8:70,887,870...71,080,169
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G |
Nfkb1 |
nuclear factor kappa B subunit 1 |
multiple interactions decreases expression |
ISO |
[demycarosyl-3D-digitoxosylmithramycin SK co-treated with Deoxyglucose] affects the expression of NFKB1 mRNA Deoxyglucose results in decreased expression of NFKB1 mRNA |
CTD |
PMID:26079942 |
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NCBI chr 2:224,016,214...224,132,135
Ensembl chr 2:224,016,214...224,110,404
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G |
Nos2 |
nitric oxide synthase 2 |
multiple interactions |
ISO |
Deoxyglucose promotes the reaction [STO 609 inhibits the reaction [Histamine results in increased phosphorylation of NOS2 protein]] |
CTD |
PMID:21145922 |
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NCBI chr10:63,815,308...63,851,208
Ensembl chr10:63,815,308...63,851,210
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G |
Npy |
neuropeptide Y |
increases expression |
EXP |
Deoxyglucose results in increased expression of NPY mRNA |
CTD |
PMID:10683841 |
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NCBI chr 4:78,881,294...78,888,495
Ensembl chr 4:78,881,264...78,888,495
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G |
Oat |
ornithine aminotransferase |
multiple interactions |
EXP |
Deoxyglucose inhibits the reaction [Cyclic AMP results in increased activity of OAT protein] |
CTD |
PMID:2827574 |
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NCBI chr 1:187,347,862...187,367,644
Ensembl chr 1:187,347,865...187,367,682
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G |
Parp1 |
poly (ADP-ribose) polymerase 1 |
multiple interactions increases cleavage |
ISO |
Deoxyglucose inhibits the reaction [Arsenic Trioxide results in increased cleavage of PARP1 protein]; Deoxyglucose inhibits the reaction [Fenretinide results in increased cleavage of PARP1 protein]; Deoxyglucose promotes the reaction [Silybin results in increased cleavage of PARP1 protein] Deoxyglucose promotes the reaction [Metformin inhibits the reaction [Arsenic Trioxide results in increased expression of PARP1 protein modified form]] Deoxyglucose results in increased cleavage of PARP1 protein |
CTD |
PMID:25246272 PMID:29095437 PMID:34053323 |
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NCBI chr13:92,307,593...92,339,406
Ensembl chr13:92,307,586...92,339,404
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G |
Pkm |
pyruvate kinase M1/2 |
multiple interactions |
ISO |
Deoxyglucose inhibits the reaction [G3BP1 protein results in increased expression of PKM protein] |
CTD |
PMID:35945655 |
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NCBI chr 8:60,057,629...60,079,600
Ensembl chr 8:60,057,402...60,079,599
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G |
Pmch |
pro-melanin-concentrating hormone |
increases expression |
EXP |
Deoxyglucose results in increased expression of PMCH mRNA |
CTD |
PMID:10683841 |
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NCBI chr 7:22,511,934...22,513,250
Ensembl chr 7:22,511,934...22,513,250
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G |
Ppara |
peroxisome proliferator activated receptor alpha |
multiple interactions |
ISO |
PPARA protein promotes the reaction [GW 7647 promotes the reaction [INS protein results in increased uptake of Deoxyglucose]] |
CTD |
PMID:21324916 |
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NCBI chr 7:116,832,405...116,900,878
Ensembl chr 7:116,832,756...116,895,346
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G |
Pparg |
peroxisome proliferator-activated receptor gamma |
affects uptake increases uptake |
ISO |
PPARG protein affects the uptake of Deoxyglucose PPARG gene polymorphism results in increased uptake of Deoxyglucose |
CTD |
PMID:18083318 |
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NCBI chr 4:148,423,102...148,548,471
Ensembl chr 4:148,423,194...148,548,468
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G |
Ppp3ca |
protein phosphatase 3 catalytic subunit alpha |
decreases response to substance |
ISO |
PPP3CA protein results in decreased susceptibility to Deoxyglucose |
CTD |
PMID:10679475 |
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NCBI chr 2:225,165,981...225,440,978
Ensembl chr 2:225,165,766...225,438,974
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G |
Pym1 |
PYM homolog 1, exon junction complex associated factor |
increases expression |
ISO |
Deoxyglucose results in increased expression of PYM1 mRNA |
CTD |
PMID:33770205 |
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NCBI chr 7:1,177,746...1,200,899
Ensembl chr 7:1,178,008...1,198,937
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G |
Raf1 |
Raf-1 proto-oncogene, serine/threonine kinase |
multiple interactions |
EXP |
RAF1 protein affects the reaction [AICA ribonucleotide results in increased uptake of Deoxyglucose] |
CTD |
PMID:11978788 |
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NCBI chr 4:148,679,534...148,740,265
Ensembl chr 4:148,679,530...148,740,317
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G |
Rnf24 |
ring finger protein 24 |
decreases expression |
ISO |
Deoxyglucose results in decreased expression of RNF24 mRNA |
CTD |
PMID:33770205 |
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NCBI chr 3:118,520,459...118,575,213
Ensembl chr 3:118,525,349...118,541,080
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G |
Rps6 |
ribosomal protein S6 |
decreases phosphorylation |
ISO |
Deoxyglucose results in decreased phosphorylation of RPS6 protein |
CTD |
PMID:23363784 |
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NCBI chr 5:101,371,716...101,374,576
Ensembl chr 5:101,371,136...101,374,602 Ensembl chr 5:101,371,136...101,374,602
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G |
Rps6kb1 |
ribosomal protein S6 kinase B1 |
decreases phosphorylation multiple interactions |
ISO |
Deoxyglucose results in decreased phosphorylation of RPS6KB1 protein Deoxyglucose results in increased phosphorylation of and results in increased activity of RPS6KB1 protein; oxophenylarsine inhibits the reaction [Deoxyglucose results in decreased phosphorylation of RPS6KB1 protein] |
CTD |
PMID:16183647 PMID:23041229 |
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NCBI chr10:71,323,777...71,367,908
Ensembl chr10:71,323,777...71,367,908
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G |
Serpinb5 |
serpin family B member 5 |
increases expression |
ISO |
Deoxyglucose analog results in increased expression of SERPINB5 protein |
CTD |
PMID:27931795 |
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NCBI chr13:22,985,557...23,005,756
Ensembl chr13:22,985,557...23,005,756
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G |
Slc16a1 |
solute carrier family 16 member 1 |
multiple interactions |
ISO |
[Lactic Acid co-treated with Deoxyglucose] promotes the reaction [[Cadmium Chloride results in increased abundance of Cadmium] which results in increased expression of SLC16A1 protein] |
CTD |
PMID:36336208 |
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NCBI chr 2:192,123,755...192,144,617
Ensembl chr 2:192,124,289...192,144,611
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G |
Slc2a1 |
solute carrier family 2 member 1 |
multiple interactions increases uptake |
ISO |
[arsenite affects the localization of SLC2A1 protein] which results in increased uptake of Deoxyglucose SLC2A1 protein results in increased uptake of Deoxyglucose [Deoxyglucose results in increased abundance of Glucose] which affects the localization of SLC2A1 protein; [sodium arsenite results in increased abundance of Arsenic] inhibits the reaction [[Deoxyglucose results in increased abundance of Glucose] which affects the localization of SLC2A1 protein]; SLC2A1 protein inhibits the reaction [INS protein results in increased uptake of Deoxyglucose] |
CTD |
PMID:2173694 PMID:14511371 PMID:31398423 |
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NCBI chr 5:132,717,196...132,745,416
Ensembl chr 5:132,717,196...132,745,416
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G |
Slc2a2 |
solute carrier family 2 member 2 |
multiple interactions increases transport |
ISO |
Cytochalasin B inhibits the reaction [SLC2A2 protein results in increased transport of Deoxyglucose]; Fructose inhibits the reaction [SLC2A2 protein results in increased transport of Deoxyglucose]; Glucose inhibits the reaction [SLC2A2 protein results in increased transport of Deoxyglucose]; Maltose inhibits the reaction [SLC2A2 protein results in increased transport of Deoxyglucose] |
CTD |
PMID:8457197 |
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NCBI chr 2:111,609,798...111,639,930
Ensembl chr 2:111,611,774...111,639,933
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G |
Slc2a3 |
solute carrier family 2 member 3 |
increases transport multiple interactions |
ISO |
SLC2A3 protein results in increased transport of Deoxyglucose Cytochalasin B inhibits the reaction [SLC2A3 protein results in increased transport of Deoxyglucose]; Galactose inhibits the reaction [SLC2A3 protein results in increased transport of Deoxyglucose]; Glucose inhibits the reaction [SLC2A3 protein results in increased transport of Deoxyglucose]; Maltose inhibits the reaction [SLC2A3 protein results in increased transport of Deoxyglucose] |
CTD |
PMID:8457197 |
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NCBI chr 4:155,960,944...156,026,000
Ensembl chr 4:155,960,946...156,025,472
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G |
Slc2a4 |
solute carrier family 2 member 4 |
multiple interactions increases uptake |
ISO EXP |
2-chloro-5-nitrobenzanilide inhibits the reaction [mangiferin promotes the reaction [SLC2A4 protein results in increased uptake of Deoxyglucose]]; [arsenite affects the localization of SLC2A4 protein] which results in increased uptake of Deoxyglucose; mangiferin promotes the reaction [SLC2A4 protein results in increased uptake of Deoxyglucose]; Plant Extracts promotes the reaction [SLC2A4 protein results in increased uptake of Deoxyglucose] [Indinavir results in decreased activity of SLC2A4 protein] inhibits the reaction [resveratrol results in increased uptake of Deoxyglucose]; SLC2A4 promotes the reaction [INS1 protein results in increased uptake of Deoxyglucose]; SLC2A4 protein promotes the reaction [resveratrol results in increased uptake of Deoxyglucose] |
CTD |
PMID:14511371 PMID:18601907 PMID:19477051 PMID:20206685 |
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NCBI chr10:54,666,015...54,671,581
Ensembl chr10:54,666,015...54,671,565
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G |
Slc2a8 |
solute carrier family 2 member 8 |
increases uptake |
EXP ISO |
SLC2A8 protein results in increased uptake of Deoxyglucose |
CTD |
PMID:23396969 |
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NCBI chr 3:16,274,918...16,284,536
Ensembl chr 3:16,274,925...16,284,464
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G |
Slc7a11 |
solute carrier family 7 member 11 |
decreases expression |
ISO |
Deoxyglucose results in decreased expression of SLC7A11 protein |
CTD |
PMID:37927237 |
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NCBI chr 2:134,382,002...134,517,622
Ensembl chr 2:133,963,107...134,517,536
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G |
Smim14 |
small integral membrane protein 14 |
decreases expression |
ISO |
Deoxyglucose results in decreased expression of SMIM14 mRNA |
CTD |
PMID:33770205 |
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NCBI chr14:42,783,361...42,829,762
Ensembl chr14:42,783,332...42,829,760
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G |
Snd1 |
staphylococcal nuclease and tudor domain containing 1 |
decreases expression |
ISO |
Deoxyglucose results in decreased expression of SND1 protein |
CTD |
PMID:37927237 |
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NCBI chr 4:57,095,205...57,494,501
Ensembl chr 4:57,095,208...57,530,843
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G |
Sod2 |
superoxide dismutase 2 |
multiple interactions |
ISO |
Deoxyglucose inhibits the reaction [manganese chloride results in increased expression of SOD2 mRNA]; Deoxyglucose inhibits the reaction [manganese chloride results in increased expression of SOD2 protein] |
CTD |
PMID:10328827 |
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NCBI chr 1:47,638,318...47,645,163
Ensembl chr 1:47,636,528...47,645,189
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G |
Sqstm1 |
sequestosome 1 |
multiple interactions |
ISO |
[bafilomycin A co-treated with Deoxyglucose co-treated with demycarosyl-3D-digitoxosylmithramycin SK] affects the expression of SQSTM1 protein; [bafilomycin A co-treated with Deoxyglucose] affects the expression of SQSTM1 protein; Deoxyglucose inhibits the reaction [demycarosyl-3D-digitoxosylmithramycin SK results in decreased expression of SQSTM1 mRNA]; Deoxyglucose promotes the reaction [demycarosyl-3D-digitoxosylmithramycin SK results in decreased expression of SQSTM1 mRNA] |
CTD |
PMID:26079942 |
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NCBI chr10:34,525,517...34,536,670
Ensembl chr10:34,525,519...34,536,673
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G |
Srebf1 |
sterol regulatory element binding transcription factor 1 |
increases expression |
ISO |
Deoxyglucose results in increased expression of SREBF1 mRNA |
CTD |
PMID:10913129 |
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NCBI chr10:45,007,637...45,029,650
Ensembl chr10:45,007,637...45,029,650
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G |
Srgap3 |
SLIT-ROBO Rho GTPase activating protein 3 |
decreases expression |
ISO |
Deoxyglucose results in decreased expression of SRGAP3 mRNA |
CTD |
PMID:33770205 |
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NCBI chr 4:145,839,369...146,070,556
Ensembl chr 4:145,840,078...146,070,575
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G |
Stk11 |
serine/threonine kinase 11 |
decreases phosphorylation |
ISO |
Deoxyglucose results in decreased phosphorylation of STK11 protein |
CTD |
PMID:23041229 |
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NCBI chr 7:9,574,553...9,591,315
Ensembl chr 7:9,575,269...9,591,315
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G |
Tent4b |
terminal nucleotidyltransferase 4B |
decreases expression |
ISO |
Deoxyglucose results in decreased expression of TENT4B mRNA |
CTD |
PMID:33770205 |
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NCBI chr19:18,807,616...18,868,969
Ensembl chr19:18,807,525...18,869,537
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G |
Tmcc3 |
transmembrane and coiled-coil domain family 3 |
decreases expression |
ISO |
Deoxyglucose results in decreased expression of TMCC3 mRNA |
CTD |
PMID:33770205 |
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NCBI chr 7:28,893,972...29,171,935
Ensembl chr 7:28,893,967...29,171,926
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G |
Tmem250 |
transmembrane protein 250 |
increases expression |
ISO |
Deoxyglucose results in increased expression of TMEM250 mRNA |
CTD |
PMID:33770205 |
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NCBI chr 3:8,962,657...8,966,349
Ensembl chr 3:8,962,657...8,966,349
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G |
Tmem87a |
transmembrane protein 87A |
increases expression |
ISO |
Deoxyglucose results in increased expression of TMEM87A mRNA |
CTD |
PMID:33770205 |
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NCBI chr 3:107,307,726...107,353,571
Ensembl chr 3:107,307,726...107,353,551
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G |
Tnf |
tumor necrosis factor |
decreases expression multiple interactions decreases response to substance |
ISO EXP |
Deoxyglucose results in decreased expression of TNF protein Quercetin inhibits the reaction [TNF protein inhibits the reaction [INS1 protein results in increased uptake of Deoxyglucose]]; TNF protein inhibits the reaction [INS1 protein results in increased uptake of Deoxyglucose] Deoxyglucose inhibits the reaction [bisphenol F results in increased secretion of TNF protein]; Quercetin inhibits the reaction [TNF protein inhibits the reaction [INS1 protein results in increased uptake of Deoxyglucose]]; TNF protein inhibits the reaction [INS1 protein results in increased uptake of Deoxyglucose] Deoxyglucose results in decreased susceptibility to TNF protein Deoxyglucose inhibits the reaction [TNF protein results in increased expression of MMP13 protein]; TNF protein inhibits the reaction [INS protein results in increased uptake of Deoxyglucose]; troglitazone inhibits the reaction [TNF protein inhibits the reaction [INS protein results in increased uptake of Deoxyglucose]] |
CTD |
PMID:16483873 PMID:21211511 PMID:21778228 PMID:22713545 PMID:23439570 PMID:34147605 More...
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NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629
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G |
Tp53 |
tumor protein p53 |
multiple interactions |
ISO |
[Deoxyglucose co-treated with demycarosyl-3D-digitoxosylmithramycin SK] results in increased expression of TP53 mRNA; Deoxyglucose promotes the reaction [demycarosyl-3D-digitoxosylmithramycin SK results in increased expression of TP53 mRNA]; TP53 protein inhibits the reaction [Deoxyglucose results in decreased abundance of Adenosine Triphosphate] |
CTD |
PMID:21042727 PMID:26079942 |
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NCBI chr10:54,300,070...54,311,525
Ensembl chr10:54,300,048...54,311,524
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G |
Txnip |
thioredoxin interacting protein |
multiple interactions |
ISO |
Deoxyglucose affects the reaction [TXNIP protein affects the reaction [Glycation End Products, Advanced results in increased activity of CASP3 protein]] |
CTD |
PMID:37632267 |
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NCBI chr 2:184,093,079...184,096,882
Ensembl chr 2:184,092,991...184,096,886
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G |
Xiap |
X-linked inhibitor of apoptosis |
multiple interactions |
ISO |
[arsenic trioxide co-treated with Deoxyglucose] results in decreased expression of XIAP protein |
CTD |
PMID:23041229 |
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NCBI chr X:120,890,537...120,938,413
Ensembl chr X:120,897,907...120,934,700
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G |
Yars2 |
tyrosyl-tRNA synthetase 2 |
increases expression |
ISO |
Deoxyglucose results in increased expression of YARS2 mRNA |
CTD |
PMID:33770205 |
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NCBI chr11:84,632,350...84,638,138
Ensembl chr11:84,624,369...84,638,125
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G |
Yes1 |
YES proto-oncogene 1, Src family tyrosine kinase |
decreases expression |
ISO |
Deoxyglucose results in decreased expression of YES1 mRNA |
CTD |
PMID:33770205 |
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NCBI chr 9:113,200,256...113,275,942
Ensembl chr 9:113,200,256...113,299,837
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G |
Zbtb1 |
zinc finger and BTB domain containing 1 |
increases expression |
ISO |
Deoxyglucose results in increased expression of ZBTB1 mRNA |
CTD |
PMID:33770205 |
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NCBI chr 6:95,096,838...95,125,811
Ensembl chr 6:95,096,387...95,118,996
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G |
Zfx |
zinc finger protein X-linked |
increases expression |
ISO |
Deoxyglucose results in increased expression of ZFX mRNA |
CTD |
PMID:33770205 |
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NCBI chr X:58,804,690...58,853,155
Ensembl chr X:58,804,691...58,853,265
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G |
Gaa |
alpha glucosidase |
multiple interactions increases metabolic processing |
ISO |
GAA gene SNP inhibits the reaction [GAA protein results in increased metabolism of 4-methylumbelliferyl glucoside] |
CTD |
PMID:21963784 |
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NCBI chr10:104,529,673...104,546,836
Ensembl chr10:104,529,747...104,546,836
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G |
Akt1 |
AKT serine/threonine kinase 1 |
multiple interactions |
ISO |
albiflorin inhibits the reaction [[Palmitic Acid co-treated with Glucose] results in increased phosphorylation of AKT1 protein] |
CTD |
PMID:37523837 |
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NCBI chr 6:131,713,716...131,735,319
Ensembl chr 6:131,713,720...131,733,921
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G |
Drd2 |
dopamine receptor D2 |
affects expression |
EXP |
albiflorin affects the expression of DRD2 |
CTD |
PMID:26475043 |
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NCBI chr 8:49,708,927...49,772,876
Ensembl chr 8:49,708,927...49,772,875
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G |
Egfr |
epidermal growth factor receptor |
multiple interactions |
ISO |
albiflorin inhibits the reaction [[Palmitic Acid co-treated with Glucose] results in increased phosphorylation of EGFR protein] |
CTD |
PMID:37523837 |
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NCBI chr14:91,176,979...91,349,722
Ensembl chr14:91,177,067...91,344,382
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G |
Htr1a |
5-hydroxytryptamine receptor 1A |
affects expression |
EXP |
albiflorin affects the expression of HTR1A |
CTD |
PMID:26475043 |
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NCBI chr 2:36,693,462...36,698,026
Ensembl chr 2:36,694,174...36,695,442
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G |
Htr2a |
5-hydroxytryptamine receptor 2A |
affects expression |
EXP |
albiflorin affects the expression of HTR2A |
CTD |
PMID:26475043 |
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NCBI chr15:49,950,035...50,022,188
Ensembl chr15:49,950,804...50,020,928
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G |
Map3k7 |
mitogen activated protein kinase kinase kinase 7 |
multiple interactions |
ISO |
Albiflorin inhibits the reaction [oxidized LDL increases phosphorylation of MAP3K7 protein in umbilical vein endothelial cells] |
RGD |
PMID:35601145 |
RGD:155804296 |
NCBI chr 5:46,356,973...46,415,597
Ensembl chr 5:46,357,931...46,415,597
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G |
Slc6a3 |
solute carrier family 6 member 3 |
affects expression |
EXP |
albiflorin affects the expression of SLC6A3 |
CTD |
PMID:26475043 |
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NCBI chr 1:29,709,443...29,750,413
Ensembl chr 1:29,709,443...29,750,413
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G |
Th |
tyrosine hydroxylase |
affects expression |
EXP |
albiflorin affects the expression of TH |
CTD |
PMID:26475043 |
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NCBI chr 1:198,071,500...198,078,832
Ensembl chr 1:198,071,503...198,109,767
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G |
Idh2 |
isocitrate dehydrogenase (NADP(+)) 2 |
increases abundance multiple interactions |
ISO |
IDH2 protein mutant form results in increased abundance of glucose-1-phosphate Triazines inhibits the reaction [IDH2 protein mutant form results in increased abundance of glucose-1-phosphate] |
CTD |
PMID:27469509 |
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NCBI chr 1:134,038,644...134,057,969
Ensembl chr 1:134,029,772...134,058,025
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G |
Abcc3 |
ATP binding cassette subfamily C member 3 |
decreases expression |
EXP |
Amikacin results in decreased expression of ABCC3 mRNA |
CTD |
PMID:27765674 |
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NCBI chr10:79,296,681...79,342,749
Ensembl chr10:79,296,693...79,342,595
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G |
Abcc4 |
ATP binding cassette subfamily C member 4 |
decreases expression |
EXP |
Amikacin results in decreased expression of ABCC4 mRNA |
CTD |
PMID:27765674 |
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NCBI chr15:95,541,186...95,774,898
Ensembl chr15:95,542,315...95,774,283
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G |
Casr |
calcium-sensing receptor |
increases activity |
ISO |
Amikacin results in increased activity of CASR protein |
CTD |
PMID:19884751 |
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NCBI chr11:64,235,251...64,304,811
Ensembl chr11:64,235,251...64,304,811
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G |
Cat |
catalase |
decreases activity multiple interactions |
ISO |
Amikacin results in decreased activity of CAT protein cefepime inhibits the reaction [Amikacin results in decreased activity of CAT protein] |
CTD |
PMID:18781908 PMID:23416261 |
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NCBI chr 3:89,842,393...89,874,577
Ensembl chr 3:89,842,399...89,874,478
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G |
Il1a |
interleukin 1 alpha |
decreases expression |
ISO |
Amikacin results in decreased expression of IL1A mRNA |
CTD |
PMID:32816093 |
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NCBI chr 3:116,526,601...116,537,055
Ensembl chr 3:116,526,604...116,536,822
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G |
Il1b |
interleukin 1 beta |
decreases expression |
ISO |
Amikacin results in decreased expression of IL1B mRNA |
CTD |
PMID:32816093 |
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NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415
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G |
Il24 |
interleukin 24 |
decreases expression |
ISO |
Amikacin results in decreased expression of IL24 mRNA |
CTD |
PMID:32816093 |
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NCBI chr13:42,353,089...42,358,487
Ensembl chr13:42,353,090...42,358,487
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G |
Pgd |
phosphogluconate dehydrogenase |
decreases activity |
EXP |
Amikacin results in decreased activity of PGD protein |
CTD |
PMID:15558954 |
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NCBI chr 5:159,582,746...159,598,945
Ensembl chr 5:159,561,271...159,742,778
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G |
Pid1 |
phosphotyrosine interaction domain containing 1 |
increases expression |
ISO |
Amikacin results in increased expression of PID1 mRNA |
CTD |
PMID:32816093 |
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NCBI chr 9:85,284,335...85,503,035
Ensembl chr 9:85,284,335...85,503,044
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G |
Ptgs2 |
prostaglandin-endoperoxide synthase 2 |
decreases expression |
ISO |
Amikacin results in decreased expression of PTGS2 mRNA |
CTD |
PMID:32816093 |
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NCBI chr13:62,163,936...62,172,193
Ensembl chr13:62,163,932...62,172,188
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G |
Slc7a11 |
solute carrier family 7 member 11 |
decreases expression |
ISO |
Amikacin results in decreased expression of SLC7A11 mRNA |
CTD |
PMID:32816093 |
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NCBI chr 2:134,382,002...134,517,622
Ensembl chr 2:133,963,107...134,517,536
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G |
Slpi |
secretory leukocyte peptidase inhibitor |
increases expression |
ISO |
Amikacin results in increased expression of SLPI mRNA |
CTD |
PMID:32816093 |
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NCBI chr 3:153,082,208...153,084,457
Ensembl chr 3:153,082,369...153,084,453
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G |
Tyr |
tyrosinase |
decreases activity |
ISO |
Amikacin results in decreased activity of TYR protein |
CTD |
PMID:23416261 |
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NCBI chr 1:141,115,036...141,210,207
Ensembl chr 1:141,115,036...141,210,207
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G |
Gypa |
glycophorin A |
increases expression |
ISO |
apigetrin results in increased expression of GYPA protein |
CTD |
PMID:25058688 |
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NCBI chr19:27,450,304...27,465,940
Ensembl chr19:27,450,308...27,465,822
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G |
Becn1 |
beclin 1 |
multiple interactions |
ISO |
asperuloside promotes the reaction [Cyclophosphamide results in increased expression of BECN1 protein]; dorsomorphin inhibits the reaction [asperuloside promotes the reaction [Cyclophosphamide results in increased expression of BECN1 protein]] |
CTD |
PMID:38348709 |
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NCBI chr10:86,231,387...86,246,742
Ensembl chr10:86,231,388...86,246,742
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G |
Csf2 |
colony stimulating factor 2 |
multiple interactions |
ISO |
asperuloside inhibits the reaction [Cyclophosphamide results in decreased expression of CSF2 protein]; dorsomorphin inhibits the reaction [asperuloside inhibits the reaction [Cyclophosphamide results in decreased expression of CSF2 protein]] |
CTD |
PMID:38348709 |
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NCBI chr10:38,386,945...38,388,926
Ensembl chr10:38,386,945...38,389,199
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G |
Epo |
erythropoietin |
multiple interactions |
ISO |
asperuloside inhibits the reaction [Cyclophosphamide results in decreased expression of EPO protein]; dorsomorphin inhibits the reaction [asperuloside inhibits the reaction [Cyclophosphamide results in decreased expression of EPO protein]] |
CTD |
PMID:38348709 |
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NCBI chr12:19,204,258...19,207,948
Ensembl chr12:19,204,508...19,207,946
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G |
Hmox1 |
heme oxygenase 1 |
multiple interactions |
ISO |
[lipopolysaccharide, E coli O55-B5 co-treated with asperuloside] results in increased expression of HMOX1 protein; asperuloside inhibits the reaction [Dextran Sulfate results in decreased expression of HMOX1 protein] |
CTD |
PMID:33974900 |
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NCBI chr19:13,466,287...13,474,082
Ensembl chr19:13,467,244...13,474,079
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G |
Il10 |
interleukin 10 |
multiple interactions |
ISO |
asperuloside inhibits the reaction [Dextran Sulfate results in decreased expression of IL10 protein] |
CTD |
PMID:33974900 |
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NCBI chr13:42,472,625...42,477,308
Ensembl chr13:42,472,839...42,477,313
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G |
Il6 |
interleukin 6 |
multiple interactions |
ISO |
asperuloside inhibits the reaction [Dextran Sulfate results in increased expression of IL6 protein]; asperuloside inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased expression of IL6 mRNA]; asperuloside inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased expression of IL6 protein] |
CTD |
PMID:33974900 |
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NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178
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G |
Kit |
KIT proto-oncogene receptor tyrosine kinase |
multiple interactions |
ISO |
asperuloside inhibits the reaction [[dorsomorphin co-treated with Cyclophosphamide] results in decreased expression of KIT protein]; asperuloside inhibits the reaction [Cyclophosphamide results in decreased expression of KIT protein] |
CTD |
PMID:38348709 |
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NCBI chr14:32,547,459...32,624,694
Ensembl chr14:32,548,877...32,624,652
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G |
Map1lc3b |
microtubule-associated protein 1 light chain 3 beta |
multiple interactions |
ISO |
asperuloside promotes the reaction [Cyclophosphamide results in increased lipidation of MAP1LC3B protein]; dorsomorphin inhibits the reaction [asperuloside promotes the reaction [Cyclophosphamide results in increased lipidation of MAP1LC3B protein]] |
CTD |
PMID:38348709 |
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NCBI chr19:49,665,795...49,673,655
Ensembl chr19:49,665,791...49,677,690
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G |
Mpo |
myeloperoxidase |
multiple interactions |
ISO |
asperuloside inhibits the reaction [Dextran Sulfate results in increased activity of MPO protein] |
CTD |
PMID:33974900 |
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NCBI chr10:72,594,883...72,608,862
Ensembl chr10:72,594,661...72,604,819
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G |
Mtor |
mechanistic target of rapamycin kinase |
multiple interactions |
ISO |
asperuloside inhibits the reaction [Cyclophosphamide results in increased phosphorylation of MTOR protein]; asperuloside inhibits the reaction [dorsomorphin promotes the reaction [Cyclophosphamide results in increased phosphorylation of MTOR protein]] |
CTD |
PMID:38348709 |
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NCBI chr 5:158,884,856...158,994,311
Ensembl chr 5:158,884,804...158,994,311
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G |
Nfe2l2 |
NFE2 like bZIP transcription factor 2 |
multiple interactions affects localization |
ISO |
[asperuloside co-treated with Dextran Sulfate] results in increased expression of NFE2L2 protein; [lipopolysaccharide, E coli O55-B5 co-treated with asperuloside] results in increased expression of NFE2L2 protein; asperuloside affects the reaction [NFE2L2 protein affects the expression of NQO1 mRNA]; asperuloside inhibits the reaction [lipopolysaccharide, E coli O55-B5 affects the localization of NFE2L2 protein] asperuloside affects the localization of NFE2L2 protein |
CTD |
PMID:33974900 |
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NCBI chr 3:60,594,239...60,621,712
Ensembl chr 3:60,594,242...60,621,737
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G |
Nqo1 |
NAD(P)H quinone dehydrogenase 1 |
multiple interactions |
ISO |
asperuloside affects the reaction [NFE2L2 protein affects the expression of NQO1 mRNA] |
CTD |
PMID:33974900 |
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NCBI chr19:35,295,633...35,310,528
Ensembl chr19:35,295,573...35,310,557
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G |
Prkaa1 |
protein kinase AMP-activated catalytic subunit alpha 1 |
multiple interactions |
ISO |
asperuloside promotes the reaction [Cyclophosphamide results in increased phosphorylation of PRKAA1 protein] |
CTD |
PMID:38348709 |
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NCBI chr 2:54,240,298...54,275,978
Ensembl chr 2:54,240,137...54,275,978
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G |
Rela |
RELA proto-oncogene, NF-kB subunit |
multiple interactions |
ISO |
asperuloside inhibits the reaction [Dextran Sulfate results in increased phosphorylation of RELA protein] |
CTD |
PMID:33974900 |
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NCBI chr 1:202,925,001...202,935,484
Ensembl chr 1:202,924,945...202,935,484
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G |
Thpo |
thrombopoietin |
multiple interactions |
ISO |
asperuloside inhibits the reaction [Cyclophosphamide results in decreased expression of THPO protein]; dorsomorphin inhibits the reaction [asperuloside inhibits the reaction [Cyclophosphamide results in decreased expression of THPO protein]] |
CTD |
PMID:38348709 |
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Ensembl chr11:80,182,820...80,188,167
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G |
Tnf |
tumor necrosis factor |
multiple interactions |
ISO |
asperuloside inhibits the reaction [Dextran Sulfate results in increased expression of TNF protein]; asperuloside inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased expression of TNF mRNA]; asperuloside inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased expression of TNF protein]; asperuloside inhibits the reaction [Lipopolysaccharides results in increased secretion of TNF protein] |
CTD |
PMID:16508180 PMID:33974900 |
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NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629
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G |
Nos2 |
nitric oxide synthase 2 |
multiple interactions |
ISO |
ganglioside, GD1b analog inhibits the reaction [[lipopolysaccharide, E. coli O26-B6 results in increased activity of NOS2 protein] which results in increased secretion of Nitrites]; ganglioside, GD1b inhibits the reaction [[lipopolysaccharide, E. coli O26-B6 results in increased activity of NOS2 protein] which results in increased secretion of Nitrites] |
CTD |
PMID:31202640 |
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NCBI chr10:63,815,308...63,851,208
Ensembl chr10:63,815,308...63,851,210
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G |
Aacs |
acetoacetyl-CoA synthetase |
increases expression |
ISO |
Glucosamine results in increased expression of AACS mRNA |
CTD |
PMID:17178593 |
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NCBI chr12:31,113,098...31,156,411
Ensembl chr12:31,113,098...31,160,954
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G |
Abcg1 |
ATP binding cassette subfamily G member 1 |
increases expression |
EXP |
Glucosamine results in increased expression of ABCG1 mRNA |
CTD |
PMID:17109745 |
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NCBI chr20:9,126,687...9,182,948
Ensembl chr20:9,126,687...9,182,948
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G |
Acaca |
acetyl-CoA carboxylase alpha |
increases expression |
ISO |
Glucosamine results in increased expression of ACACA mRNA |
CTD |
PMID:22096489 |
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NCBI chr10:69,014,261...69,276,453
Ensembl chr10:69,014,170...69,276,457
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G |
Acan |
aggrecan |
multiple interactions increases expression decreases expression affects expression |
ISO EXP |
Glucosamine analog affects the reaction [IL1B results in decreased expression of ACAN mRNA]; Glucosamine inhibits the reaction [IL1B protein results in decreased expression of ACAN mRNA]; Glucosamine results in decreased cleavage of and results in decreased secretion of ACAN protein Glucosamine results in increased expression of ACAN mRNA Glucosamine inhibits the reaction [IL1B results in decreased expression of ACAN mRNA] Glucosamine analog results in increased expression of ACAN protein; Glucosamine results in increased expression of ACAN mRNA; Glucosamine results in increased expression of ACAN protein Glucosamine analog results in decreased expression of ACAN mRNA Glucosamine analog affects the expression of ACAN mRNA |
CTD |
PMID:12801482 PMID:16300972 PMID:16872674 PMID:17109745 PMID:17337215 PMID:18321735 PMID:19909832 More...
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NCBI chr 1:132,981,582...133,044,416
Ensembl chr 1:132,981,582...133,043,627
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Acot1 |
acyl-CoA thioesterase 1 |
increases expression |
ISO |
Glucosamine results in increased expression of ACOT1 mRNA |
CTD |
PMID:17178593 |
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NCBI chr 6:103,636,173...103,644,167
Ensembl chr 6:103,636,041...103,644,163
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G |
Acox2 |
acyl-CoA oxidase 2 |
decreases expression |
ISO |
Glucosamine results in decreased expression of ACOX2 mRNA |
CTD |
PMID:17178593 |
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NCBI chr15:16,660,584...16,692,160
Ensembl chr15:16,660,272...16,692,160
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Acss2 |
acyl-CoA synthetase short-chain family member 2 |
increases expression |
ISO |
Glucosamine results in increased expression of ACSS2 mRNA |
CTD |
PMID:17178593 |
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NCBI chr 3:144,003,808...144,047,452
Ensembl chr 3:144,004,336...144,059,675
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G |
Adam15 |
ADAM metallopeptidase domain 15 |
multiple interactions decreases expression |
EXP |
Glucosamine affects the reaction [IL1B results in decreased expression of ADAM15 mRNA]; IL1B affects the reaction [Glucosamine results in decreased expression of ADAM15 mRNA] |
CTD |
PMID:17109745 |
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NCBI chr 2:174,754,629...174,765,136
Ensembl chr 2:174,754,633...174,765,113
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G |
Adam17 |
ADAM metallopeptidase domain 17 |
multiple interactions increases expression |
EXP |
Glucosamine inhibits the reaction [IL1B results in increased expression of ADAM17 mRNA]; IL1B affects the reaction [Glucosamine results in increased expression of ADAM17 mRNA] |
CTD |
PMID:17109745 |
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NCBI chr 6:40,872,936...40,920,700
Ensembl chr 6:40,872,856...40,920,639
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G |
Adamts1 |
ADAM metallopeptidase with thrombospondin type 1 motif, 1 |
decreases expression multiple interactions |
ISO EXP |
Glucosamine analog results in decreased expression of ADAMTS1 mRNA Glucosamine results in decreased expression of ADAMTS1 mRNA Glucosamine inhibits the reaction [IL1B results in increased expression of ADAMTS1 mRNA]; IL1B inhibits the reaction [Glucosamine results in decreased expression of ADAMTS1 mRNA] |
CTD |
PMID:16300972 PMID:17109745 |
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NCBI chr11:24,932,227...24,941,068
Ensembl chr11:24,931,761...24,941,103
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Adamts20 |
ADAM metallopeptidase with thrombospondin type 1 motif, 20 |
decreases cleavage |
ISO |
Glucosamine results in decreased cleavage of ADAMTS20 protein alternative form |
CTD |
PMID:19909832 |
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NCBI chr 7:125,396,227...125,528,020
Ensembl chr 7:125,397,734...125,527,777
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Adamts4 |
ADAM metallopeptidase with thrombospondin type 1 motif, 4 |
increases expression |
EXP |
Glucosamine results in increased expression of ADAMTS4 mRNA |
CTD |
PMID:17109745 |
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NCBI chr13:83,670,556...83,680,045
Ensembl chr13:83,670,183...83,680,065
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Adamts5 |
ADAM metallopeptidase with thrombospondin type 1 motif, 5 |
decreases expression multiple interactions |
ISO |
Glucosamine analog results in decreased expression of ADAMTS5 mRNA Glucosamine results in decreased cleavage of and results in decreased activity of ADAMTS5 protein alternative form |
CTD |
PMID:16300972 PMID:19909832 |
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NCBI chr11:25,000,627...25,047,205
Ensembl chr11:25,000,637...25,047,205
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Adamts9 |
ADAM metallopeptidase with thrombospondin type 1 motif, 9 |
decreases cleavage |
ISO |
Glucosamine results in decreased cleavage of ADAMTS9 protein alternative form |
CTD |
PMID:19909832 |
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NCBI chr 4:125,290,633...125,462,988
Ensembl chr 4:125,291,490...125,462,929
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Adipoq |
adiponectin, C1Q and collagen domain containing |
increases expression |
ISO EXP |
Glucosamine results in increased expression of ADIPOQ mRNA |
CTD |
PMID:15694357 |
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NCBI chr11:77,721,912...77,735,644
Ensembl chr11:77,721,912...77,735,564
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G |
Afp |
alpha-fetoprotein |
increases expression |
ISO |
Glucosamine results in increased expression of AFP mRNA |
CTD |
PMID:17178593 |
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NCBI chr14:17,573,412...17,591,476
Ensembl chr14:17,573,412...17,591,480
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Agt |
angiotensinogen |
increases expression |
ISO |
Glucosamine results in increased expression of AGT mRNA |
CTD |
PMID:17178593 |
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NCBI chr19:52,529,139...52,549,618
Ensembl chr19:52,529,185...52,540,977
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G |
Ahi1 |
Abelson helper integration site 1 |
decreases expression |
ISO |
Glucosamine results in decreased expression of AHI1 mRNA |
CTD |
PMID:17178593 |
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NCBI chr 1:15,762,485...15,891,213
Ensembl chr 1:15,762,462...15,891,041
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G |
Akt1 |
AKT serine/threonine kinase 1 |
affects phosphorylation multiple interactions |
ISO |
Glucosamine analog affects the phosphorylation of AKT1 protein Glucosamine inhibits the reaction [INS1 protein results in increased phosphorylation of AKT1 protein]; OSTN protein affects the reaction [Glucosamine inhibits the reaction [INS1 protein results in increased phosphorylation of AKT1 protein]] Glucosamine analog affects the reaction [IL1B results in increased phosphorylation of AKT1 protein]; Glucosamine promotes the reaction [IL1B results in increased phosphorylation of AKT1 protein] |
CTD |
PMID:18080321 PMID:18340449 PMID:30602124 |
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NCBI chr 6:131,713,716...131,735,319
Ensembl chr 6:131,713,720...131,733,921
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G |
Alb |
albumin |
multiple interactions |
EXP |
[LEPR protein affects the susceptibility to Glucosamine] which affects the expression of ALB protein |
CTD |
PMID:33345901 |
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NCBI chr14:17,607,397...17,622,814
Ensembl chr14:17,607,381...17,622,836
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G |
Alg12 |
ALG12, alpha-1,6-mannosyltransferase |
decreases expression |
ISO |
Glucosamine results in decreased expression of ALG12 mRNA |
CTD |
PMID:17178593 |
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NCBI chr 7:119,895,112...119,909,488
Ensembl chr 7:119,895,120...119,909,458
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Alpl |
alkaline phosphatase, biomineralization associated |
multiple interactions increases expression increases activity |
ISO |
4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide inhibits the reaction [Glucosamine analog results in increased activity of ALPL protein] Glucosamine analog results in increased expression of ALPL mRNA |
CTD |
PMID:20458730 |
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NCBI chr 5:149,951,397...150,006,424
Ensembl chr 5:149,951,409...150,006,446
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G |
Apoa1 |
apolipoprotein A1 |
increases secretion increases stability |
ISO |
Glucosamine results in increased secretion of APOA1 protein Glucosamine results in increased stability of APOA1 mRNA |
CTD |
PMID:15164326 |
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NCBI chr 8:46,527,251...46,529,035
Ensembl chr 8:46,527,144...46,529,035
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G |
Apob |
apolipoprotein B |
multiple interactions increases degradation increases ubiquitination decreases secretion decreases localization decreases expression |
ISO EXP |
acetylleucyl-leucyl-norleucinal inhibits the reaction [Glucosamine results in decreased expression of and results in decreased secretion of APOB protein]; Glucosamine results in decreased expression of and results in decreased secretion of APOB protein; Oleic Acid inhibits the reaction [Glucosamine results in decreased secretion of APOB protein] Oleic Acid inhibits the reaction [Glucosamine results in increased degradation of APOB protein] Glucosamine results in increased ubiquitination of APOB protein Glucosamine results in decreased localization of APOB protein Glucosamine results in decreased expression of APOB protein |
CTD |
PMID:15618547 PMID:19383982 |
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NCBI chr 6:30,844,386...30,883,983
Ensembl chr 6:30,844,368...30,892,497
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Apoe |
apolipoprotein E |
multiple interactions |
ISO |
[Streptozocin co-treated with APOE mutant form] results in increased abundance of Glucosamine; INS1 inhibits the reaction [[Streptozocin co-treated with APOE mutant form] results in increased abundance of Glucosamine] |
CTD |
PMID:16380481 |
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NCBI chr 1:79,353,924...79,357,852
Ensembl chr 1:79,353,916...79,357,932
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G |
Ass1 |
argininosuccinate synthase 1 |
multiple interactions |
EXP |
Glucosamine inhibits the reaction [IL1B results in increased expression of ASS1 mRNA] |
CTD |
PMID:17109745 |
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NCBI chr 3:14,747,355...14,796,909
Ensembl chr 3:14,747,368...14,796,903
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G |
Atf3 |
activating transcription factor 3 |
decreases expression |
ISO |
Glucosamine results in decreased expression of ATF3 mRNA |
CTD |
PMID:17178593 |
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NCBI chr13:102,751,278...102,800,520
Ensembl chr13:102,751,321...102,764,631
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G |
Atf4 |
activating transcription factor 4 |
increases expression multiple interactions |
ISO |
Glucosamine results in increased expression of ATF4 mRNA; Glucosamine results in increased expression of ATF4 protein NUS1 protein inhibits the reaction [Glucosamine results in increased expression of ATF4 mRNA] 4-phenylbutyric acid inhibits the reaction [Glucosamine results in increased expression of ATF4 mRNA]; 4-phenylbutyric acid inhibits the reaction [Glucosamine results in increased expression of ATF4 protein]; EIF2AK3 protein affects the reaction [Glucosamine results in increased expression of ATF4 mRNA]; GSK2656157 inhibits the reaction [Glucosamine results in increased expression of ATF4 mRNA] |
CTD |
PMID:30602124 PMID:33812996 |
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NCBI chr 7:111,804,135...111,806,457
Ensembl chr 7:111,804,183...111,806,446
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G |
Atf6 |
activating transcription factor 6 |
multiple interactions increases expression decreases expression |
ISO EXP |
4-phenylbutyric acid inhibits the reaction [Glucosamine results in increased expression of ATF6 mRNA]; ATF6 mutant form inhibits the reaction [Glucosamine results in decreased expression of MEF2A mRNA]; ATF6 mutant form inhibits the reaction [Glucosamine results in decreased expression of MEF2A protein]; ATF6 mutant form inhibits the reaction [Glucosamine results in decreased expression of PPARGC1A mRNA]; ATF6 mutant form inhibits the reaction [Glucosamine results in decreased expression of PPARGC1A protein]; ATF6 mutant form inhibits the reaction [Glucosamine results in decreased expression of SLC2A4 mRNA]; ATF6 mutant form inhibits the reaction [Glucosamine results in decreased expression of SLC2A4 protein]; NUS1 protein inhibits the reaction [Glucosamine results in increased expression of ATF6 mRNA]; ursodoxicoltaurine inhibits the reaction [Glucosamine results in increased expression of ATF6 mRNA] Glucosamine results in increased expression of ATF6 protein ATF6 protein affects the reaction [Glucosamine results in increased expression of OSTN mRNA] 4-phenylbutyric acid inhibits the reaction [Glucosamine results in increased expression of ATF6 mRNA]; ATF6 mutant form inhibits the reaction [Glucosamine results in decreased expression of MEF2A mRNA]; ATF6 mutant form inhibits the reaction [Glucosamine results in decreased expression of MEF2A protein]; ATF6 mutant form inhibits the reaction [Glucosamine results in decreased expression of PPARGC1A mRNA]; ATF6 mutant form inhibits the reaction [Glucosamine results in decreased expression of PPARGC1A protein]; ATF6 mutant form inhibits the reaction [Glucosamine results in decreased expression of SLC2A4 mRNA]; ATF6 mutant form inhibits the reaction [Glucosamine results in decreased expression of SLC2A4 protein]; ursodoxicoltaurine inhibits the reaction [Glucosamine results in increased expression of ATF6 mRNA] Glucosamine results in decreased expression of ATF6 mRNA |
CTD |
PMID:17178593 PMID:19383982 PMID:20165829 PMID:30602124 PMID:33812996 |
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NCBI chr13:82,927,579...83,106,381
Ensembl chr13:82,930,034...83,107,177
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G |
Atf7ip |
activating transcription factor 7 interacting protein |
increases expression |
ISO |
Glucosamine results in increased expression of ATF7IP mRNA |
CTD |
PMID:17178593 |
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NCBI chr 4:169,385,872...169,471,652
Ensembl chr 4:169,385,872...169,471,650
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G |
Atp2a2 |
ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 2 |
decreases expression |
ISO |
Glucosamine results in decreased expression of ATP2A2 mRNA |
CTD |
PMID:17178593 |
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NCBI chr12:34,072,710...34,122,142
Ensembl chr12:34,072,683...34,122,101
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G |
Azin1 |
antizyme inhibitor 1 |
decreases expression multiple interactions |
EXP |
Glucosamine results in decreased expression of AZIN1 mRNA IL1B promotes the reaction [Glucosamine results in increased expression of AZIN1 mRNA] |
CTD |
PMID:17109745 |
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NCBI chr 7:69,654,773...69,681,578
Ensembl chr 7:69,654,663...69,681,578
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G |
B3gat3 |
beta-1,3-glucuronyltransferase 3 |
multiple interactions increases expression |
EXP |
[XDH protein co-treated with Hypoxanthine] inhibits the reaction [Glucosamine results in increased expression of B3GAT3 mRNA]; Glucosamine inhibits the reaction [IL1B protein results in decreased activity of B3GAT3 protein]; Glucosamine inhibits the reaction [IL1B protein results in decreased expression of B3GAT3 mRNA] |
CTD |
PMID:11229466 PMID:11801247 |
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NCBI chr 1:205,817,374...205,823,928
Ensembl chr 1:205,817,378...205,837,807
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G |
Bcl2l1 |
Bcl2-like 1 |
decreases expression multiple interactions |
ISO |
Glucosamine results in decreased expression of BCL2L1 protein pepstatin inhibits the reaction [Glucosamine results in decreased expression of BCL2L1 protein] |
CTD |
PMID:15972124 PMID:16850161 |
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NCBI chr 3:141,253,508...141,304,582
Ensembl chr 3:141,253,523...141,303,479
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G |
Bdnf |
brain-derived neurotrophic factor |
decreases expression |
ISO |
Glucosamine results in decreased expression of BDNF mRNA |
CTD |
PMID:17178593 |
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NCBI chr 3:96,165,042...96,215,621
Ensembl chr 3:96,165,042...96,215,615
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G |
Bglap |
bone gamma-carboxyglutamate protein |
increases expression |
ISO |
Glucosamine analog results in increased expression of BGLAP mRNA |
CTD |
PMID:20458730 |
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NCBI chr 2:173,838,518...173,839,495
Ensembl chr 2:173,838,518...173,839,495
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G |
Bgn |
biglycan |
multiple interactions decreases expression |
EXP |
Glucosamine inhibits the reaction [IL1B results in increased expression of BGN mRNA]; IL1B affects the reaction [Glucosamine results in decreased expression of BGN mRNA] |
CTD |
PMID:17109745 |
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NCBI chr X:151,197,296...151,209,458
Ensembl chr X:151,197,273...151,209,461
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G |
Bmal1 |
basic helix-loop-helix ARNT like 1 |
decreases expression |
ISO |
Glucosamine results in decreased expression of BMAL1 mRNA; Glucosamine results in decreased expression of BMAL1 protein |
CTD |
PMID:24442997 |
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NCBI chr 1:167,331,756...167,430,235
Ensembl chr 1:167,331,633...167,430,231
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G |
Bmp2 |
bone morphogenetic protein 2 |
multiple interactions |
EXP |
Glucosamine inhibits the reaction [IL1B results in increased expression of BMP2 mRNA] |
CTD |
PMID:17109745 |
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NCBI chr 3:120,812,660...120,822,579
Ensembl chr 3:120,812,882...120,821,397
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G |
Bmp4 |
bone morphogenetic protein 4 |
decreases expression multiple interactions |
EXP |
Glucosamine results in decreased expression of BMP4 mRNA Glucosamine promotes the reaction [IL1B results in decreased expression of BMP4 mRNA] |
CTD |
PMID:17109745 |
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NCBI chr15:19,618,538...19,633,494
Ensembl chr15:19,618,542...19,623,306
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G |
Bmp6 |
bone morphogenetic protein 6 |
multiple interactions decreases expression |
EXP |
Glucosamine inhibits the reaction [IL1B results in increased expression of BMP6 mRNA] Glucosamine results in decreased expression of BMP6 mRNA |
CTD |
PMID:17109745 |
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NCBI chr17:26,318,121...26,469,691
Ensembl chr17:26,318,569...26,470,365
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G |
Bmp7 |
bone morphogenetic protein 7 |
multiple interactions increases expression |
EXP |
Glucosamine inhibits the reaction [IL1B results in increased expression of BMP7 mRNA] Glucosamine results in increased expression of BMP7 mRNA |
CTD |
PMID:17109745 |
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NCBI chr 3:161,639,915...161,716,938
Ensembl chr 3:161,516,462...161,716,788
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G |
Calr |
calreticulin |
decreases expression |
ISO |
Glucosamine results in decreased expression of CALR mRNA |
CTD |
PMID:17178593 |
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NCBI chr19:23,308,525...23,313,420
Ensembl chr19:23,308,351...23,313,414
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G |
Car3 |
carbonic anhydrase 3 |
decreases expression |
EXP |
Glucosamine results in decreased expression of CAR3 mRNA |
CTD |
PMID:17109745 |
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NCBI chr 2:86,770,418...86,780,011
Ensembl chr 2:86,770,420...86,784,280
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G |
Casp3 |
caspase 3 |
increases cleavage multiple interactions |
ISO |
Glucosamine results in increased cleavage of CASP3 protein Glucosamine results in increased activity of and results in increased cleavage of CASP3 protein |
CTD |
PMID:16850161 PMID:22020377 |
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NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648
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G |
Casp4 |
caspase 4 |
decreases expression |
ISO |
Glucosamine results in decreased expression of CASP4 mRNA |
CTD |
PMID:17178593 |
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NCBI chr 8:2,599,017...2,635,097
Ensembl chr 8:2,598,876...2,635,092
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G |
Cbr2 |
carbonyl reductase 2 |
increases expression |
ISO |
Glucosamine results in increased expression of CBR2 mRNA |
CTD |
PMID:17178593 |
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NCBI chr10:106,008,535...106,012,838
Ensembl chr10:105,991,589...106,013,001
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G |
Cbr3 |
carbonyl reductase 3 |
increases expression |
ISO |
Glucosamine results in increased expression of CBR3 mRNA |
CTD |
PMID:17178593 |
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NCBI chr11:33,008,615...33,016,877
Ensembl chr11:33,008,615...33,016,875
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G |
Ccl2 |
C-C motif chemokine ligand 2 |
multiple interactions increases expression |
ISO EXP |
Alloxan inhibits the reaction [Glucosamine inhibits the reaction [Cathelicidins results in increased expression of CCL2 protein]]; Glucosamine analog inhibits the reaction [IL1B results in increased secretion of CCL2 protein]; Glucosamine inhibits the reaction [Cathelicidins results in increased expression of CCL2 mRNA]; Glucosamine inhibits the reaction [Cathelicidins results in increased expression of CCL2 protein]; Glucosamine inhibits the reaction [TNF results in increased expression of CCL2 mRNA]; Glucosamine inhibits the reaction [TNF results in increased expression of CCL2 protein] Glucosamine results in increased expression of CCL2 mRNA Glucosamine inhibits the reaction [IL1B results in increased expression of CCL2 mRNA]; IL1B promotes the reaction [Glucosamine results in increased expression of CCL2 mRNA] |
CTD |
PMID:17109745 PMID:18080321 PMID:18949387 PMID:19020780 |
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NCBI chr10:67,005,424...67,007,222
Ensembl chr10:67,005,424...67,007,226
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G |
Ccl20 |
C-C motif chemokine ligand 20 |
multiple interactions increases expression |
EXP |
Glucosamine inhibits the reaction [IL1B results in increased expression of CCL20 mRNA]; IL1B promotes the reaction [Glucosamine results in increased expression of CCL20 mRNA] |
CTD |
PMID:17109745 |
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NCBI chr 9:84,389,031...84,391,629
Ensembl chr 9:84,388,904...84,391,629
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G |
Ccl22 |
C-C motif chemokine ligand 22 |
multiple interactions |
EXP |
Glucosamine inhibits the reaction [IL1B results in increased expression of CCL22 mRNA] |
CTD |
PMID:17109745 |
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NCBI chr19:10,257,602...10,264,373
Ensembl chr19:10,257,601...10,264,400
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G |
Ccl3 |
C-C motif chemokine ligand 3 |
multiple interactions |
EXP |
Glucosamine inhibits the reaction [IL1B results in increased expression of CCL3 mRNA] |
CTD |
PMID:17109745 |
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NCBI chr10:68,451,388...68,452,938
Ensembl chr10:68,451,388...68,452,938
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G |
Ccl5 |
C-C motif chemokine ligand 5 |
multiple interactions |
ISO EXP |
Glucosamine analog inhibits the reaction [IL1B results in increased secretion of CCL5 protein] Glucosamine inhibits the reaction [IL1B results in increased expression of CCL5 mRNA] |
CTD |
PMID:17109745 PMID:18080321 |
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NCBI chr10:68,322,826...68,327,380
Ensembl chr10:68,322,829...68,327,377
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G |
Ccl7 |
C-C motif chemokine ligand 7 |
multiple interactions increases expression |
EXP |
Glucosamine inhibits the reaction [IL1B results in increased expression of CCL7 mRNA]; IL1B promotes the reaction [Glucosamine results in increased expression of CCL7 mRNA] |
CTD |
PMID:17109745 |
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NCBI chr10:67,016,446...67,018,296
Ensembl chr10:67,016,446...67,018,303
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G |
Ccn2 |
cellular communication network factor 2 |
increases expression |
EXP |
Glucosamine analog results in increased expression of CCN2 mRNA |
CTD |
PMID:21466783 |
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NCBI chr 1:20,802,199...20,805,315
Ensembl chr 1:20,802,199...20,805,734
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G |
Ccnb1 |
cyclin B1 |
decreases expression |
EXP |
Glucosamine results in decreased expression of CCNB1 mRNA |
CTD |
PMID:17109745 |
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NCBI chr 2:31,912,190...31,921,163
Ensembl chr 2:31,912,193...31,921,172
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G |
Cd24 |
CD24 molecule |
increases expression |
ISO |
Glucosamine results in increased expression of CD24A mRNA |
CTD |
PMID:17178593 |
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NCBI chr20:47,074,353...47,079,662
Ensembl chr20:47,073,512...47,079,662
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G |
Cd28 |
Cd28 molecule |
increases expression |
EXP |
Glucosamine results in increased expression of CD28 mRNA |
CTD |
PMID:17109745 |
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NCBI chr 9:62,166,324...62,194,674
Ensembl chr 9:62,166,192...62,194,685
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G |
Cdc20 |
cell division cycle 20 |
decreases expression |
EXP |
Glucosamine results in decreased expression of CDC20 mRNA |
CTD |
PMID:17109745 |
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NCBI chr 5:131,966,203...131,970,406
Ensembl chr 5:131,966,215...131,970,512
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G |
Cdc23 |
cell division cycle 23 |
decreases expression |
EXP |
Glucosamine results in decreased expression of CDC23 mRNA |
CTD |
PMID:17109745 |
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NCBI chr18:26,236,891...26,260,611
Ensembl chr18:26,236,890...26,291,163
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G |
Cdk1 |
cyclin-dependent kinase 1 |
decreases expression |
EXP |
Glucosamine results in decreased expression of CDK1 mRNA |
CTD |
PMID:17109745 |
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NCBI chr20:19,266,226...19,281,417
Ensembl chr20:19,266,248...19,281,408
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G |
Cdkn1a |
cyclin-dependent kinase inhibitor 1A |
increases expression |
EXP ISO |
Glucosamine results in increased expression of CDKN1A protein Glucosamine results in increased expression of CDKN1A mRNA |
CTD |
PMID:15654767 PMID:17178593 |
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NCBI chr20:7,149,177...7,159,727
Ensembl chr20:7,149,217...7,159,585
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G |
Cdkn1b |
cyclin-dependent kinase inhibitor 1B |
decreases expression |
EXP |
Glucosamine results in decreased expression of CDKN1B protein |
CTD |
PMID:15654767 |
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NCBI chr 4:167,760,067...167,765,177
Ensembl chr 4:167,760,181...167,764,982
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G |
Cdkn3 |
cyclin-dependent kinase inhibitor 3 |
decreases expression |
EXP |
Glucosamine results in decreased expression of CDKN3 mRNA |
CTD |
PMID:17109745 |
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NCBI chr15:20,022,522...20,033,948
Ensembl chr15:20,022,664...20,033,945
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G |
Cenpf |
centromere protein F |
decreases expression |
EXP |
Glucosamine results in decreased expression of CENPF mRNA |
CTD |
PMID:17109745 |
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NCBI chr13:101,184,127...101,229,714
Ensembl chr13:101,184,127...101,229,669
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G |
Chi3l1 |
chitinase 3 like 1 |
decreases expression |
ISO |
Glucosamine analog results in decreased expression of CHI3L1 mRNA |
CTD |
PMID:16142878 |
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NCBI chr13:45,641,802...45,649,787
Ensembl chr13:45,641,802...45,649,787
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G |
Chuk |
component of inhibitor of nuclear factor kappa B kinase complex |
multiple interactions decreases activity |
ISO |
Glucosamine analog results in decreased activity of and results in decreased localization of CHUK protein Glucosamine analog results in decreased activity of CHUK protein |
CTD |
PMID:20113495 |
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NCBI chr 1:242,959,539...242,995,066
Ensembl chr 1:242,959,760...242,995,065
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G |
Ckap2 |
cytoskeleton associated protein 2 |
decreases expression |
EXP |
Glucosamine results in decreased expression of CKAP2 mRNA |
CTD |
PMID:17109745 |
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NCBI chr16:69,839,668...69,864,852
Ensembl chr16:69,839,630...69,864,913
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G |
Clock |
clock circadian regulator |
decreases expression |
ISO |
Glucosamine results in decreased expression of CLOCK mRNA; Glucosamine results in decreased expression of CLOCK protein |
CTD |
PMID:24442997 |
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NCBI chr14:31,908,542...31,992,673
Ensembl chr14:31,908,566...31,990,400
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G |
Clta |
clathrin, light chain A |
decreases expression |
EXP |
Glucosamine results in decreased expression of CLTA mRNA |
CTD |
PMID:17109745 |
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NCBI chr 5:58,244,253...58,263,480
Ensembl chr 5:58,245,442...58,263,472
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G |
Col11a1 |
collagen type XI alpha 1 chain |
multiple interactions decreases expression |
EXP |
Glucosamine inhibits the reaction [IL1B results in decreased expression of COL11A1 mRNA]; IL1B affects the reaction [Glucosamine results in decreased expression of COL11A1 mRNA] |
CTD |
PMID:17109745 |
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NCBI chr 2:201,820,715...202,013,853
Ensembl chr 2:201,820,715...202,013,853
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G |
Col1a1 |
collagen type I alpha 1 chain |
multiple interactions decreases expression |
ISO |
Glucosamine inhibits the reaction [IL1B protein results in increased expression of COL1A1 mRNA] Glucosamine results in decreased expression of COL1A1 mRNA |
CTD |
PMID:18321735 |
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NCBI chr10:79,883,622...79,900,625
Ensembl chr10:79,883,622...79,900,624
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G |
Col2a1 |
collagen type II alpha 1 chain |
multiple interactions affects expression increases expression |
ISO EXP |
Glucosamine analog affects the reaction [IL1B results in decreased expression of COL2A1 mRNA]; Glucosamine inhibits the reaction [IL1B protein results in decreased expression of COL2A1 mRNA] Glucosamine inhibits the reaction [IL1B results in decreased expression of COL2A1 mRNA] Glucosamine analog affects the expression of COL2A1 mRNA Glucosamine analog results in increased expression of COL2A1 mRNA; Glucosamine results in increased expression of COL2A1 mRNA |
CTD |
PMID:16300972 PMID:17109745 PMID:17337215 PMID:18321735 |
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NCBI chr 7:129,098,489...129,127,560
Ensembl chr 7:129,098,786...129,127,546
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G |
Col3a1 |
collagen type III alpha 1 chain |
multiple interactions |
EXP |
Glucosamine inhibits the reaction [IL1B results in decreased expression of COL3A1 mRNA] |
CTD |
PMID:17109745 |
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NCBI chr 9:47,374,611...47,410,547
Ensembl chr 9:47,374,593...47,410,547
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G |
Col8a1 |
collagen type VIII alpha 1 chain |
multiple interactions decreases expression |
EXP |
Glucosamine inhibits the reaction [IL1B results in increased expression of COL8A1 mRNA]; IL1B inhibits the reaction [Glucosamine results in decreased expression of COL8A1 mRNA] |
CTD |
PMID:17109745 |
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NCBI chr11:42,776,851...42,906,432
Ensembl chr11:42,777,628...42,906,424
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G |
Csf1 |
colony stimulating factor 1 |
multiple interactions decreases expression |
EXP |
Glucosamine inhibits the reaction [IL1B results in increased expression of CSF1 mRNA]; IL1B inhibits the reaction [Glucosamine results in decreased expression of CSF1 mRNA] |
CTD |
PMID:17109745 |
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NCBI chr 2:195,377,215...195,396,608
Ensembl chr 2:195,377,215...195,411,704
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G |
Csf2 |
colony stimulating factor 2 |
multiple interactions increases expression |
EXP |
Glucosamine inhibits the reaction [IL1B results in increased expression of CSF2 mRNA] Glucosamine results in increased expression of CSF2 mRNA |
CTD |
PMID:17109745 |
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NCBI chr10:38,386,945...38,388,926
Ensembl chr10:38,386,945...38,389,199
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G |
Csf3 |
colony stimulating factor 3 |
multiple interactions increases expression |
EXP |
Glucosamine inhibits the reaction [IL1B results in increased expression of CSF3 mRNA] Glucosamine results in increased expression of CSF3 mRNA |
CTD |
PMID:17109745 |
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NCBI chr10:83,660,787...83,664,569
Ensembl chr10:83,661,207...83,663,603
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G |
Ctsd |
cathepsin D |
affects localization multiple interactions increases activity decreases expression |
ISO |
Glucosamine affects the localization of CTSD protein pepstatin inhibits the reaction [Glucosamine results in decreased expression of CTSD protein alternative form] Glucosamine results in increased activity of CTSD protein |
CTD |
PMID:15972124 PMID:16850161 |
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NCBI chr 1:197,527,467...197,539,343
Ensembl chr 1:197,527,467...197,539,488
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G |
Cul2 |
cullin 2 |
multiple interactions |
ISO |
Glucosamine analog inhibits the reaction [TNF results in increased expression of CUL2 mRNA]; Glucosamine inhibits the reaction [TNF results in increased expression of CUL2 mRNA] |
CTD |
PMID:18173918 |
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NCBI chr17:54,169,093...54,210,197
Ensembl chr17:54,169,086...54,209,968
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G |
Cxcl1 |
C-X-C motif chemokine ligand 1 |
multiple interactions decreases expression |
EXP |
Glucosamine inhibits the reaction [IL1B results in increased expression of CXCL1 mRNA]; IL1B inhibits the reaction [Glucosamine results in decreased expression of CXCL1 mRNA] |
CTD |
PMID:17109745 |
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NCBI chr14:17,193,364...17,195,143
Ensembl chr14:17,193,365...17,195,215
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G |
Cxcl10 |
C-X-C motif chemokine ligand 10 |
multiple interactions |
ISO EXP |
Glucosamine inhibits the reaction [Lipopolysaccharides results in increased expression of CXCL10 mRNA] Glucosamine inhibits the reaction [IL1B results in increased expression of CXCL10 mRNA] |
CTD |
PMID:17109745 PMID:20737476 |
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NCBI chr14:15,704,772...15,706,969
Ensembl chr14:15,704,758...15,706,975
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G |
Cxcl11 |
C-X-C motif chemokine ligand 11 |
multiple interactions |
EXP |
Glucosamine inhibits the reaction [IL1B results in increased expression of CXCL11 mRNA] |
CTD |
PMID:17109745 |
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NCBI chr14:15,689,432...15,692,207
Ensembl chr14:15,689,424...15,692,271
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G |
Cxcl12 |
C-X-C motif chemokine ligand 12 |
multiple interactions decreases expression |
EXP |
Glucosamine promotes the reaction [IL1B results in decreased expression of CXCL12 mRNA]; IL1B affects the reaction [Glucosamine results in decreased expression of CXCL12 mRNA] |
CTD |
PMID:17109745 |
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NCBI chr 4:150,388,326...150,401,173
Ensembl chr 4:150,388,325...150,401,168
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G |
Cxcl2 |
C-X-C motif chemokine ligand 2 |
multiple interactions increases expression |
EXP |
Glucosamine inhibits the reaction [IL1B results in increased expression of CXCL2 mRNA]; IL1B promotes the reaction [Glucosamine results in increased expression of CXCL2 mRNA] |
CTD |
PMID:17109745 |
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NCBI chr14:17,181,030...17,183,075
Ensembl chr14:17,181,062...17,183,075
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G |
Cxcl3 |
C-X-C motif chemokine ligand 3 |
multiple interactions increases expression |
EXP |
Glucosamine inhibits the reaction [IL1B results in increased expression of CXCL3 mRNA]; IL1B promotes the reaction [Glucosamine results in increased expression of CXCL3 mRNA] |
CTD |
PMID:17109745 |
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NCBI chr14:17,287,727...17,289,451
Ensembl chr14:17,270,146...17,289,511
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G |
Cxcl6 |
C-X-C motif chemokine ligand 6 |
multiple interactions |
EXP |
Glucosamine inhibits the reaction [IL1B results in increased expression of CXCL5 mRNA] |
CTD |
PMID:17109745 |
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NCBI chr14:17,310,790...17,312,250
Ensembl chr14:17,310,426...17,313,093
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G |
Cyba |
cytochrome b-245 alpha chain |
decreases expression |
ISO |
Glucosamine results in decreased expression of CYBA mRNA |
CTD |
PMID:18077487 |
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NCBI chr19:50,487,598...50,495,669
Ensembl chr19:50,487,597...50,495,721
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G |
Cycs |
cytochrome c, somatic |
affects localization |
ISO |
Glucosamine affects the localization of CYCS protein |
CTD |
PMID:15972124 PMID:22020377 |
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NCBI chr 4:79,651,894...79,653,994
Ensembl chr 4:79,651,378...79,654,054 Ensembl chr18:79,651,378...79,654,054
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G |
Cyp51 |
cytochrome P450, family 51 |
increases expression |
ISO |
Glucosamine results in increased expression of CYP51 mRNA |
CTD |
PMID:17178593 |
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NCBI chr 4:30,036,956...30,055,410
Ensembl chr 4:30,036,865...30,055,410
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G |
Dbi |
diazepam binding inhibitor |
increases expression |
ISO |
Glucosamine results in increased expression of DBI mRNA |
CTD |
PMID:17178593 |
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NCBI chr13:31,241,466...31,249,853
Ensembl chr13:31,206,988...31,268,693
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G |
Ddit3 |
DNA-damage inducible transcript 3 |
increases expression multiple interactions decreases expression |
ISO |
Glucosamine results in increased expression of DDIT3 mRNA; Glucosamine results in increased expression of DDIT3 protein NUS1 protein inhibits the reaction [Glucosamine results in increased expression of DDIT3 mRNA] 4-phenylbutyric acid inhibits the reaction [Glucosamine results in increased expression of DDIT3 mRNA]; 4-phenylbutyric acid inhibits the reaction [Glucosamine results in increased expression of DDIT3 protein] Glucosamine results in decreased expression of DDIT3 mRNA |
CTD |
PMID:16380481 PMID:17178593 PMID:30602124 PMID:33812996 |
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NCBI chr 7:63,115,645...63,121,203
Ensembl chr 7:63,116,380...63,121,201
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G |
Ddit4l |
DNA-damage-inducible transcript 4-like |
increases expression |
EXP |
Glucosamine results in increased expression of DDIT4L mRNA |
CTD |
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