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The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at The data is made available under the Creative Commons License (CC BY 3.0, For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:cholesterol sulfate
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Accession:CHEBI:41321 term browser browse the term
Definition:A steroid sulfate that is cholesterol substituted by a sulfoxy group at position 3.
Synonyms:exact_synonym: cholest-5-en-3beta-yl hydrogen sulfate
 related_synonym: CHOLEST-5-EN-3-YL HYDROGEN SULFATE;   Cholest-5-en-3beta-ol sulfate;   Cholesterol 3-sulfate;   Cholesterol 3-sulphate;   Cholesterol hydrogen sulfate;   Cholesterol hydrogen sulphate;   Cholesterol sulphate;   Cholesteryl sulphate;   Formula=C27H46O4S;   InChI=1S/C27H46O4S/c1-18(2)7-6-8-19(3)23-11-12-24-22-10-9-20-17-21(31-32(28,29)30)13-15-26(20,4)25(22)14-16-27(23,24)5/h9,18-19,21-25H,6-8,10-17H2,1-5H3,(H,28,29,30)/t19-,21+,22+,23-,24+,25+,26+,27-/m1/s1;   InChIKey=BHYOQNUELFTYRT-DPAQBDIFSA-N;   SMILES=O(S(O)(=O)=O)[C@@H]1CC=2[C@]([C@]3(CC[C@]4([C@]([C@@]3(CC2)[H])(CC[C@@]4([C@H](C)CCCC(C)C)[H])[H])C)[H])(C)CC1;   cholesteryl sulfate
 alt_id: CHEBI:35377;   CHEBI:41316;   CHEBI:86594
 xref: Beilstein:3225885;   CAS:1256-86-6;   HMDB:HMDB0000653;   KEGG:C18043
 xref_mesh: MESH:C007045
 xref: PDBeChem:C3S;   Reaxys:3225885
 cyclic_relationship: is_conjugate_acid_of CHEBI:136579

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cholesterol sulfate term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cyp11a1 cytochrome P450, family 11, subfamily a, polypeptide 1 decreases expression ISO cholesteryl sulfate results in decreased expression of CYP11A1 mRNA CTD PMID:18490834 NCBI chr 8:62,798,317...62,809,848
Ensembl chr 8:62,779,875...62,809,893
JBrowse link
G Star steroidogenic acute regulatory protein decreases expression ISO cholesteryl sulfate results in decreased expression of STAR mRNA; cholesteryl sulfate results in decreased expression of STAR protein CTD PMID:18490834 NCBI chr16:71,036,204...71,040,847
Ensembl chr16:71,036,204...71,040,847
JBrowse link
G Sult2b1 sulfotransferase family 2B member 1 increases abundance ISO SULT2B1 protein results in increased abundance of cholesteryl sulfate CTD PMID:27052460 NCBI chr 1:101,712,254...101,774,683
Ensembl chr 1:101,710,959...101,773,508
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19773
    role 19719
      biological role 19719
        biochemical role 19312
          metabolite 19294
            eukaryotic metabolite 18958
              algal metabolite 13677
                cholesterol 317
                  cholesterol sulfate 3
Path 2
Term Annotations click to browse term
  CHEBI ontology 19773
    subatomic particle 19772
      composite particle 19772
        hadron 19772
          baryon 19772
            nucleon 19772
              atomic nucleus 19772
                atom 19772
                  main group element atom 19662
                    p-block element atom 19662
                      carbon group element atom 19579
                        carbon atom 19569
                          organic molecular entity 19569
                            organic molecule 19502
                              organic cyclic compound 19329
                                organic polycyclic compound 16514
                                  steroid 13053
                                    hydroxy steroid 12651
                                      3-hydroxy steroid 10359
                                        3beta-hydroxy steroid 2008
                                          3beta-hydroxy-Delta(5)-steroid 1840
                                            cholesterol 317
                                              cholesterol sulfate 3
paths to the root