CHEBI ONTOLOGY - ANNOTATIONS
The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/ . The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/ ). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term: cholesterol sulfate
Accession: CHEBI:41321
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Definition: A steroid sulfate that is cholesterol substituted by a sulfoxy group at position 3.
Synonyms: exact_synonym: cholest-5-en-3beta-yl hydrogen sulfate
related_synonym: CHOLEST-5-EN-3-YL HYDROGEN SULFATE; Cholest-5-en-3beta-ol sulfate; Cholesterol 3-sulfate; Cholesterol 3-sulphate; Cholesterol hydrogen sulfate; Cholesterol hydrogen sulphate; Cholesterol sulphate; Cholesteryl sulphate; Formula=C27H46O4S; InChI=1S/C27H46O4S/c1-18(2)7-6-8-19(3)23-11-12-24-22-10-9-20-17-21(31-32(28,29)30)13-15-26(20,4)25(22)14-16-27(23,24)5/h9,18-19,21-25H,6-8,10-17H2,1-5H3,(H,28,29,30)/t19-,21+,22+,23-,24+,25+,26+,27-/m1/s1; InChIKey=BHYOQNUELFTYRT-DPAQBDIFSA-N; SMILES=O(S(O)(=O)=O)[C@@H]1CC=2[C@]([C@]3(CC[C@]4([C@]([C@@]3(CC2)[H])(CC[C@@]4([C@H](C)CCCC(C)C)[H])[H])C)[H])(C)CC1; cholesteryl sulfate
alt_id: CHEBI:35377; CHEBI:41316; CHEBI:86594
xref: Beilstein:3225885; CAS:1256-86-6; HMDB:HMDB0000653; KEGG:C18043
xref_mesh: MESH:C007045
xref: PDBeChem:C3S; Reaxys:3225885
cyclic_relationship: is_conjugate_acid_of CHEBI:136579
G
Cyp11a1
cytochrome P450, family 11, subfamily a, polypeptide 1
decreases expression
ISO
cholesteryl sulfate results in decreased expression of CYP11A1 mRNA
CTD
PMID:18490834
NCBI chr 8:58,422,807...58,434,342
Ensembl chr 8:58,404,669...58,434,338
G
Star
steroidogenic acute regulatory protein
decreases expression
ISO
cholesteryl sulfate results in decreased expression of STAR mRNA; cholesteryl sulfate results in decreased expression of STAR protein
CTD
PMID:18490834
NCBI chr16:66,267,094...66,274,368
Ensembl chr16:66,264,807...66,271,672
G
Sult2b1
sulfotransferase family 2B member 1
increases abundance
ISO
SULT2B1 protein results in increased abundance of cholesteryl sulfate
CTD
PMID:27052460
NCBI chr 1:96,200,155...96,261,295
Ensembl chr 1:96,200,156...96,261,295
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