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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:1H-benzimidazole
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Accession:CHEBI:41275 term browser browse the term
Definition:The 1H-tautomer of benzimidazole.
Synonyms:related_synonym: 1,3-benzodiazole;   1,3-diazaindene;   Benzimidazole;   Formula=C7H6N2;   Hbim;   Hbzim;   InChI=1S/C7H6N2/c1-2-4-7-6(3-1)8-5-9-7/h1-5H,(H,8,9);   InChIKey=HYZJCKYKOHLVJF-UHFFFAOYSA-N;   SMILES=c1ccc2[nH]cnc2c1;   azindole;   benzoglyoxaline;   o-benzimidazole
 alt_id: CHEBI:3028;   CHEBI:41272
 xref: Beilstein:109682;   CAS:51-17-2;   DrugBank:DB02962;   Gmelin:3106;   KEGG:C02009
 xref_mesh: MESH:C031000
 xref: MetaCyc:BENZIMIDAZOLE;   PDBeChem:BZI;   PMID:24152176;   PMID:8070089;   Reaxys:109682;   Wikipedia:Benzimidazole
 cyclic_relationship: is_conjugate_acid_of CHEBI:33173;   is_tautomer_of CHEBI:36623;   is_tautomer_of CHEBI:36639;   is_tautomer_of CHEBI:36641


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1H-benzimidazole term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Epas1 endothelial PAS domain protein 1 increases stability EXP benzimidazole results in increased stability of EPAS1 protein CTD PMID:23545307 NCBI chr 6:10,306,508...10,385,239
Ensembl chr 6:10,306,405...10,387,265
JBrowse link
G Trpv1 transient receptor potential cation channel, subfamily V, member 1 multiple interactions EXP benzimidazole analog inhibits the reaction [Capsaicin results in increased activity of TRPV1 protein]; benzimidazole analog inhibits the reaction [Protons results in increased activity of TRPV1 protein]; capsazepine inhibits the reaction [benzimidazole analog inhibits the reaction [Protons results in increased activity of TRPV1 protein]]; N-(3-methoxyphenyl)-4-chlorocinnamanilide inhibits the reaction [benzimidazole analog inhibits the reaction [Protons results in increased activity of TRPV1 protein]] CTD PMID:16135784 NCBI chr10:59,799,123...59,824,208
Ensembl chr10:59,799,123...59,824,679
JBrowse link
clemizole term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cyp2b3 cytochrome P450, family 2, subfamily b, polypeptide 3 increases expression
multiple interactions
ISO clemizole results in increased expression of CYP2B6 mRNA
[clemizole co-treated with NR1I3 protein alternative form] results in increased expression of CYP2B6 mRNA; [clemizole co-treated with NR1I3 protein mutant form] results in increased expression of CYP2B6 mRNA
CTD PMID:31312845 NCBI chr 1:83,163,103...83,236,615
Ensembl chr 1:83,163,079...83,236,615
JBrowse link
G G6pc1 glucose-6-phosphatase catalytic subunit 1 increases expression ISO clemizole results in increased expression of G6PC1 mRNA CTD PMID:31312845 NCBI chr10:89,286,009...89,296,213
Ensembl chr10:89,285,855...89,296,213
JBrowse link
G Med1 mediator complex subunit 1 multiple interactions ISO clemizole promotes the reaction [MED1 protein binds to NR1I3 protein alternative form] CTD PMID:31312845 NCBI chr10:86,101,560...86,145,271
Ensembl chr10:86,103,600...86,144,880
JBrowse link
G Ncoa1 nuclear receptor coactivator 1 multiple interactions ISO clemizole promotes the reaction [NCOA1 protein binds to NR1I3 protein alternative form]; clemizole promotes the reaction [NCOA1 protein binds to NR1I3 protein] CTD PMID:31312845 NCBI chr 6:28,677,563...28,931,844
Ensembl chr 6:28,677,540...28,931,843
JBrowse link
G Ncoa3 nuclear receptor coactivator 3 multiple interactions ISO clemizole promotes the reaction [NCOA3 protein binds to NR1I3 protein] CTD PMID:31312845 NCBI chr 3:162,692,176...162,788,582
Ensembl chr 3:162,692,185...162,787,548
JBrowse link
G Nr1i2 nuclear receptor subfamily 1, group I, member 2 multiple interactions
increases activity
ISO [clemizole results in increased activity of NR1I2 protein] which results in increased expression of CYP3A4 mRNA CTD PMID:31312845 NCBI chr11:65,022,100...65,058,546
Ensembl chr11:65,022,100...65,058,545
JBrowse link
G Nr1i3 nuclear receptor subfamily 1, group I, member 3 affects localization
affects binding
multiple interactions
ISO clemizole affects the localization of NR1I3 protein mutant form
clemizole binds to NR1I3 protein
[clemizole co-treated with NR1I3 protein alternative form] results in increased expression of CYP2B6 mRNA; [clemizole co-treated with NR1I3 protein mutant form] results in increased expression of CYP2B6 mRNA; clemizole binds to and results in increased activity of NR1I3 protein alternative form; clemizole inhibits the reaction [ethyl (5-(diethylglycyl)-10,11-dihydro-5H-dibenzo(b,f)azepin-3-yl)carbamate results in decreased activity of NR1I3 protein]; clemizole promotes the reaction [MED1 protein binds to NR1I3 protein alternative form]; clemizole promotes the reaction [NCOA1 protein binds to NR1I3 protein alternative form]; clemizole promotes the reaction [NCOA1 protein binds to NR1I3 protein]; clemizole promotes the reaction [NCOA3 protein binds to NR1I3 protein]
CTD PMID:31312845 NCBI chr13:89,585,072...89,591,278
Ensembl chr13:89,586,283...89,591,277
JBrowse link
G Pck1 phosphoenolpyruvate carboxykinase 1 increases expression ISO clemizole results in increased expression of PCK1 mRNA CTD PMID:31312845 NCBI chr 3:171,213,936...171,219,885
Ensembl chr 3:171,213,936...171,219,871
JBrowse link
G Scd stearoyl-CoA desaturase decreases expression ISO clemizole results in decreased expression of SCD mRNA CTD PMID:31312845 NCBI chr 1:264,159,966...264,173,061
Ensembl chr 1:264,160,129...264,172,729
JBrowse link
G Thrsp thyroid hormone responsive affects expression ISO clemizole affects the expression of THRSP mRNA CTD PMID:31312845 NCBI chr 1:162,381,251...162,385,575
Ensembl chr 1:162,381,253...162,385,575
JBrowse link
mebendazole term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcb1a ATP binding cassette subfamily B member 1A decreases expression ISO Mebendazole results in decreased expression of ABCB1 mRNA; Mebendazole results in decreased expression of ABCB1 protein CTD PMID:28606429 NCBI chr 4:22,339,829...22,517,642
Ensembl chr 4:22,133,521...22,425,515
JBrowse link
G Abcc1 ATP binding cassette subfamily C member 1 decreases expression ISO Mebendazole results in decreased expression of ABCC1 mRNA CTD PMID:28606429 NCBI chr10:549,537...672,235
Ensembl chr10:549,883...672,196
JBrowse link
G Ager advanced glycosylation end product-specific receptor increases expression ISO Mebendazole results in increased expression of AGER mRNA CTD PMID:24747151 NCBI chr20:4,363,152...4,366,079
Ensembl chr20:4,363,152...4,366,079
JBrowse link
G Arhgef2 Rho/Rac guanine nucleotide exchange factor 2 decreases expression ISO Mebendazole results in decreased expression of ARHGEF2 protein CTD PMID:30075109 NCBI chr 2:187,964,100...188,022,847
Ensembl chr 2:187,977,008...188,021,377
JBrowse link
G Bax BCL2 associated X, apoptosis regulator multiple interactions ISO [Mebendazole results in increased phosphorylation of BCL2 protein] inhibits the reaction [BCL2 protein binds to BAX protein] CTD PMID:18667591 NCBI chr 1:101,451,801...101,457,207
Ensembl chr 1:101,451,802...101,457,207
JBrowse link
G Bcl2 BCL2, apoptosis regulator affects response to substance
increases phosphorylation
multiple interactions
ISO BCL2 protein affects the susceptibility to Mebendazole
Mebendazole results in increased phosphorylation of BCL2 protein
[Mebendazole results in increased phosphorylation of BCL2 protein] inhibits the reaction [BCL2 protein binds to BAX protein]
CTD PMID:18667591 NCBI chr13:26,605,426...26,769,374
Ensembl chr13:26,605,426...26,769,374
JBrowse link
G Bmp6 bone morphogenetic protein 6 increases expression ISO Mebendazole results in increased expression of BMP6 mRNA CTD PMID:32816093 NCBI chr17:26,955,142...27,112,820
Ensembl chr17:26,955,142...27,112,820
JBrowse link
G Ccl2 C-C motif chemokine ligand 2 increases expression ISO Mebendazole results in increased expression of CCL2 protein CTD PMID:20116850 NCBI chr10:69,412,065...69,413,863
Ensembl chr10:69,412,017...69,413,870
JBrowse link
G Cdh1 cadherin 1 multiple interactions ISO Mebendazole inhibits the reaction [TGFB1 protein results in increased expression of CDH1 protein] CTD PMID:30075109 NCBI chr19:38,768,467...38,838,395
Ensembl chr19:38,768,467...38,838,395
JBrowse link
G Cdh2 cadherin 2 multiple interactions ISO Mebendazole inhibits the reaction [TGFB1 protein results in increased expression of CDH2 protein] CTD PMID:30075109 NCBI chr18:8,146,971...8,366,037
Ensembl chr18:8,146,971...8,360,684
JBrowse link
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 increases expression ISO
EXP
Mebendazole results in increased expression of CYP1A1 mRNA; Mebendazole results in increased expression of CYP1A1 protein CTD PMID:9860486 PMID:12841937 NCBI chr 8:62,472,087...62,478,122
Ensembl chr 8:62,472,095...62,478,147
JBrowse link
G Cyp1a2 cytochrome P450, family 1, subfamily a, polypeptide 2 increases expression ISO
EXP
Mebendazole results in increased expression of CYP1A2 protein CTD PMID:12841937 NCBI chr 8:62,451,360...62,458,244
Ensembl chr 8:62,451,329...62,458,301
JBrowse link
G Ereg epiregulin increases expression ISO Mebendazole results in increased expression of EREG mRNA CTD PMID:32816093 NCBI chr14:18,577,620...18,591,395
Ensembl chr14:18,576,355...18,591,394
JBrowse link
G Fos Fos proto-oncogene, AP-1 transcription factor subunit increases expression ISO Mebendazole results in increased expression of FOS mRNA CTD PMID:12730611 NCBI chr 6:109,300,433...109,303,299
Ensembl chr 6:109,300,433...109,303,299
JBrowse link
G Gstp1 glutathione S-transferase pi 1 multiple interactions ISO Mebendazole inhibits the reaction [GSTP1 protein results in increased metabolism of 1-chloro-2,4-dinitrobenzene-glutathione conjugate] CTD PMID:23769903 NCBI chr 1:219,291,679...219,294,147
Ensembl chr 1:219,291,679...219,294,147
JBrowse link
G Hes1 hes family bHLH transcription factor 1 decreases expression ISO Mebendazole results in decreased expression of HES1 protein CTD PMID:32277947 NCBI chr11:74,312,837...74,315,249
Ensembl chr11:74,312,806...74,315,248
JBrowse link
G Il1a interleukin 1 alpha increases expression ISO Mebendazole results in increased expression of IL1A mRNA CTD PMID:32816093 NCBI chr 3:121,824,712...121,836,122
Ensembl chr 3:121,825,412...121,836,086
JBrowse link
G Il1b interleukin 1 beta increases expression ISO Mebendazole results in increased expression of IL1B mRNA CTD PMID:32816093 NCBI chr 3:121,876,256...121,882,637
Ensembl chr 3:121,876,263...121,882,726
JBrowse link
G Il24 interleukin 24 increases expression ISO Mebendazole results in increased expression of IL24 mRNA CTD PMID:32816093 NCBI chr13:47,618,451...47,623,849
Ensembl chr13:47,618,452...47,623,849
JBrowse link
G Il6r interleukin 6 receptor increases expression ISO Mebendazole results in increased expression of IL6R protein modified form CTD PMID:20116850 NCBI chr 2:189,196,180...189,255,987
Ensembl chr 2:189,205,701...189,254,628
JBrowse link
G Mapk1 mitogen activated protein kinase 1 increases phosphorylation ISO Mebendazole results in increased phosphorylation of MAPK1 protein CTD PMID:20848085 NCBI chr11:88,203,863...88,273,301
Ensembl chr11:88,211,599...88,273,254
JBrowse link
G Mapk3 mitogen activated protein kinase 3 increases phosphorylation ISO Mebendazole results in increased phosphorylation of MAPK3 protein CTD PMID:20848085 NCBI chr 1:198,192,773...198,198,975
Ensembl chr 1:198,192,773...198,198,975
JBrowse link
G Mapk8 mitogen-activated protein kinase 8 increases phosphorylation ISO Mebendazole results in increased phosphorylation of MAPK8 protein CTD PMID:20848085 NCBI chr16:9,620,854...9,709,342
Ensembl chr16:9,625,177...9,709,347
JBrowse link
G Mapk9 mitogen-activated protein kinase 9 increases phosphorylation ISO Mebendazole results in increased phosphorylation of MAPK9 protein CTD PMID:20848085 NCBI chr10:35,333,859...35,374,364
Ensembl chr10:35,333,859...35,374,355
JBrowse link
G Mapt microtubule-associated protein tau decreases expression ISO Mebendazole results in decreased expression of MAPT protein CTD PMID:16930453 NCBI chr10:92,289,002...92,386,517
Ensembl chr10:92,288,910...92,386,517
JBrowse link
G Met MET proto-oncogene, receptor tyrosine kinase increases expression ISO Mebendazole results in increased expression of MET mRNA CTD PMID:32816093 NCBI chr 4:44,747,467...44,854,628
Ensembl chr 4:44,774,741...44,852,665
JBrowse link
G Myc MYC proto-oncogene, bHLH transcription factor decreases expression ISO Mebendazole results in decreased expression of MYC mRNA; Mebendazole results in decreased expression of MYC protein CTD PMID:31207347 PMID:32277947 NCBI chr 7:102,586,313...102,591,240
Ensembl chr 7:102,586,313...102,591,240
JBrowse link
G Nlrp3 NLR family, pyrin domain containing 3 increases expression ISO Mebendazole results in increased expression of NLRP3 mRNA CTD PMID:24747151 NCBI chr10:45,884,324...45,918,290
Ensembl chr10:45,893,018...45,918,254
JBrowse link
G Notch1 notch receptor 1 decreases expression ISO Mebendazole results in decreased expression of NOTCH1 protein CTD PMID:32277947 NCBI chr 3:3,905,562...3,951,015
Ensembl chr 3:3,905,453...3,951,025
JBrowse link
G Nr1h4 nuclear receptor subfamily 1, group H, member 4 multiple interactions ISO Mebendazole inhibits the reaction [pregna-4,17-diene-3,16-dione results in decreased activity of NR1H4 protein] CTD PMID:25257666 NCBI chr 7:30,003,429...30,162,095
Ensembl chr 7:30,003,429...30,162,056
JBrowse link
G Pid1 phosphotyrosine interaction domain containing 1 increases expression ISO Mebendazole results in increased expression of PID1 mRNA CTD PMID:32816093 NCBI chr 9:91,667,748...91,683,468
Ensembl chr 9:91,665,986...91,882,927
JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 increases expression ISO Mebendazole results in increased expression of PTGS2 mRNA CTD PMID:32816093 NCBI chr13:67,351,230...67,356,920
Ensembl chr13:67,351,087...67,359,335
JBrowse link
G Ptk2 protein tyrosine kinase 2 decreases expression ISO Mebendazole results in decreased expression of PTK2 protein CTD PMID:30075109 NCBI chr 7:114,436,419...114,611,317
Ensembl chr 7:114,437,361...114,590,119
JBrowse link
G Rac1 Rac family small GTPase 1 decreases expression ISO Mebendazole results in decreased expression of RAC1 protein CTD PMID:30075109 NCBI chr12:13,090,316...13,111,841
Ensembl chr12:13,090,172...13,111,873
JBrowse link
G Rhoa ras homolog family member A decreases expression ISO Mebendazole results in decreased expression of RHOA protein CTD PMID:30075109 NCBI chr 8:117,082,440...117,116,244
Ensembl chr 8:117,106,576...117,116,167
JBrowse link
G S100a8 S100 calcium binding protein A8 increases expression ISO Mebendazole results in increased expression of S100A8 mRNA CTD PMID:24747151 NCBI chr 2:190,073,239...190,074,333
Ensembl chr 2:190,073,815...190,074,354
JBrowse link
G S100a9 S100 calcium binding protein A9 increases expression ISO Mebendazole results in increased expression of S100A9 mRNA CTD PMID:24747151 NCBI chr 2:190,097,436...190,100,209
Ensembl chr 2:190,097,554...190,100,276
JBrowse link
G Slc47a1 solute carrier family 47 member 1 decreases expression ISO Mebendazole results in decreased expression of SLC47A1 mRNA CTD PMID:28606429 NCBI chr10:47,631,425...47,685,379
Ensembl chr10:47,632,192...47,666,921
JBrowse link
G Slc7a11 solute carrier family 7 member 11 increases expression ISO Mebendazole results in increased expression of SLC7A11 mRNA CTD PMID:32816093 NCBI chr 2:139,453,774...139,528,479
Ensembl chr 2:139,453,774...139,528,162
JBrowse link
G Slpi secretory leukocyte peptidase inhibitor increases expression ISO Mebendazole results in increased expression of SLPI mRNA CTD PMID:32816093 NCBI chr 3:160,799,979...160,802,228
Ensembl chr 3:160,799,981...160,802,433
JBrowse link
G Tgfb1 transforming growth factor, beta 1 multiple interactions ISO Mebendazole inhibits the reaction [TGFB1 protein results in increased expression of CDH1 protein]; Mebendazole inhibits the reaction [TGFB1 protein results in increased expression of CDH2 protein] CTD PMID:30075109 NCBI chr 1:82,480,875...82,497,196
Ensembl chr 1:82,480,195...82,497,199
JBrowse link
G Thra thyroid hormone receptor alpha multiple interactions ISO Mebendazole binds to and results in decreased activity of THRA protein CTD PMID:25752796 NCBI chr10:86,657,285...86,684,935
Ensembl chr10:86,657,285...86,684,933
JBrowse link
G Tnf tumor necrosis factor multiple interactions
increases expression
increases secretion
ISO U 0126 inhibits the reaction [Mebendazole results in increased secretion of TNF protein]
Mebendazole results in increased expression of TNF mRNA
CTD PMID:20848085 PMID:24747151 NCBI chr20:5,189,382...5,192,000
Ensembl chr20:5,189,390...5,192,000
Ensembl chr20:5,189,390...5,192,000
JBrowse link
G Vegfa vascular endothelial growth factor A increases expression ISO Mebendazole results in increased expression of VEGFA protein CTD PMID:20116850 NCBI chr 9:17,340,341...17,355,681
Ensembl chr 9:17,340,341...17,355,681
JBrowse link
thiabendazole term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Alb albumin decreases expression EXP Thiabendazole results in decreased expression of ALB mRNA CTD PMID:18539377 NCBI chr14:19,176,275...19,191,793
Ensembl chr14:19,176,277...19,191,863
JBrowse link
G Casp3 caspase 3 increases activity EXP Thiabendazole results in increased activity of CASP3 protein CTD PMID:26748015 NCBI chr16:48,845,011...48,863,249
Ensembl chr16:48,845,012...48,863,204
JBrowse link
G Casp8 caspase 8 increases activity EXP Thiabendazole results in increased activity of CASP8 protein CTD PMID:26748015 NCBI chr 9:65,614,142...65,662,624
Ensembl chr 9:65,614,142...65,662,106
JBrowse link
G Casp9 caspase 9 increases activity EXP Thiabendazole results in increased activity of CASP9 protein CTD PMID:26748015 NCBI chr 5:160,356,211...160,373,774
Ensembl chr 5:160,355,833...160,373,778
JBrowse link
G Chmp5 charged multivesicular body protein 5 affects expression EXP Thiabendazole affects the expression of CHMP5 mRNA CTD PMID:18539377 NCBI chr 5:57,267,312...57,284,455
Ensembl chr 5:57,267,312...57,284,448
JBrowse link
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 multiple interactions
increases expression
increases activity
EXP
ISO
herbimycin inhibits the reaction [Thiabendazole results in increased activity of CYP1A1 protein]; herbimycin inhibits the reaction [Thiabendazole results in increased expression of CYP1A1 mRNA]; herbimycin inhibits the reaction [Thiabendazole results in increased expression of CYP1A1 protein]
Thiabendazole results in increased expression of CYP1A1 mRNA; Thiabendazole results in increased expression of CYP1A1 protein
CTD PMID:8900397 PMID:10103034 PMID:11226373 PMID:14987951 PMID:15110098 NCBI chr 8:62,472,087...62,478,122
Ensembl chr 8:62,472,095...62,478,147
JBrowse link
G Cyp1a2 cytochrome P450, family 1, subfamily a, polypeptide 2 multiple interactions
increases expression
affects metabolic processing
decreases activity
ISO
EXP
beta-Naphthoflavone promotes the reaction [CYP1A2 protein affects the metabolism of Thiabendazole]
Thiabendazole results in increased expression of CYP1A2 mRNA; Thiabendazole results in increased expression of CYP1A2 protein
Thiabendazole results in decreased activity of CYP1A2 protein
CTD PMID:10936227 PMID:11124226 PMID:12920490 PMID:15110098 PMID:16261361 PMID:18539377 PMID:18570159 NCBI chr 8:62,451,360...62,458,244
Ensembl chr 8:62,451,329...62,458,301
JBrowse link
G Cyp2b1 cytochrome P450, family 2, subfamily b, polypeptide 1 increases expression EXP Thiabendazole results in increased expression of CYP2B1 mRNA; Thiabendazole results in increased expression of CYP2B1 protein CTD PMID:15110098 NCBI chr 7:99,142,431...99,183,540
Ensembl chr 7:99,142,450...99,181,783
JBrowse link
G Cyp2b2 cytochrome P450, family 2, subfamily b, polypeptide 2 increases expression EXP Thiabendazole results in increased expression of CYP2B2 mRNA; Thiabendazole results in increased expression of CYP2B2 protein CTD PMID:15110098 NCBI chr 1:83,103,925...83,119,578
Ensembl chr 1:83,103,925...83,119,193
JBrowse link
G Cyp2b3 cytochrome P450, family 2, subfamily b, polypeptide 3 increases expression ISO Thiabendazole results in increased expression of CYP2B6 mRNA CTD PMID:18570159 NCBI chr 1:83,163,103...83,236,615
Ensembl chr 1:83,163,079...83,236,615
JBrowse link
G Gadd45a growth arrest and DNA-damage-inducible, alpha increases expression EXP Thiabendazole results in increased expression of GADD45A mRNA CTD PMID:18539377 NCBI chr 4:97,782,512...97,784,814
Ensembl chr 4:97,782,512...97,784,842
JBrowse link
G Gclc glutamate-cysteine ligase, catalytic subunit increases activity
multiple interactions
ISO Thiabendazole results in increased activity of GCLC protein
[Thiabendazole co-treated with Buthionine Sulfoximine] results in increased activity of GCLC protein
CTD PMID:11019651 NCBI chr 8:85,059,051...85,097,471
Ensembl chr 8:85,059,051...85,097,468
JBrowse link
G Gstp1 glutathione S-transferase pi 1 increases expression EXP Thiabendazole results in increased expression of GSTP1 mRNA CTD PMID:15110098 NCBI chr 1:219,291,679...219,294,147
Ensembl chr 1:219,291,679...219,294,147
JBrowse link
G Gstt1 glutathione S-transferase theta 1 increases expression EXP Thiabendazole results in increased expression of GSTT1 mRNA CTD PMID:15110098 NCBI chr20:13,799,102...13,816,527
Ensembl chr20:13,799,102...13,816,526
JBrowse link
G Mpo myeloperoxidase increases metabolic processing ISO MPO protein results in increased metabolism of Thiabendazole metabolite CTD PMID:21513789 NCBI chr10:75,087,892...75,098,260
Ensembl chr10:75,087,892...75,098,260
JBrowse link
G Nppb natriuretic peptide B increases expression EXP Thiabendazole results in increased expression of NPPB mRNA CTD PMID:18539377 NCBI chr 5:164,796,176...164,797,538
Ensembl chr 5:164,796,185...164,797,531
JBrowse link
G Nr1i2 nuclear receptor subfamily 1, group I, member 2 increases activity ISO Thiabendazole results in increased activity of NR1I2 protein CTD PMID:25455453 NCBI chr11:65,022,100...65,058,546
Ensembl chr11:65,022,100...65,058,545
JBrowse link
G Oxct1 3-oxoacid CoA transferase 1 affects expression EXP Thiabendazole affects the expression of OXCT1 mRNA CTD PMID:18539377 NCBI chr 2:53,859,738...54,007,733
Ensembl chr 2:53,859,737...54,007,756
JBrowse link
G Pfkfb1 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1 increases expression EXP Thiabendazole results in increased expression of PFKFB1 mRNA CTD PMID:18539377 NCBI chr  X:23,092,143...23,145,923
Ensembl chr  X:23,092,159...23,144,324
JBrowse link
G Prkcb protein kinase C, beta increases expression EXP Thiabendazole results in increased expression of PRKCB mRNA CTD PMID:18539377 NCBI chr 1:192,233,569...192,575,339
Ensembl chr 1:192,233,910...192,574,831
JBrowse link
G Taf9b TATA-box binding protein associated factor 9b affects expression EXP Thiabendazole affects the expression of TAF9B mRNA CTD PMID:18539377 NCBI chr  X:77,281,234...77,295,238
Ensembl chr  X:77,281,210...77,295,426
JBrowse link
G Tp53 tumor protein p53 increases expression EXP Thiabendazole results in increased expression of TP53 mRNA CTD PMID:18539377 NCBI chr10:56,186,299...56,198,449
Ensembl chr10:56,187,020...56,198,449
JBrowse link
G Trim3 tripartite motif-containing 3 increases expression EXP Thiabendazole results in increased expression of TRIM3 mRNA CTD PMID:18539377 NCBI chr 1:170,441,662...170,464,341
Ensembl chr 1:170,441,639...170,464,341
JBrowse link
G Ugdh UDP-glucose 6-dehydrogenase increases expression EXP Thiabendazole results in increased expression of UGDH mRNA CTD PMID:18539377 NCBI chr14:44,479,614...44,502,845
Ensembl chr14:44,479,614...44,502,845
JBrowse link
G Utrn utrophin increases expression ISO Thiabendazole results in increased expression of UTRN mRNA CTD PMID:22028826 NCBI chr 1:6,451,809...6,970,040
Ensembl chr 1:6,451,810...6,970,040
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19781
    chemical entity 19781
      molecular entity 19779
        mancude ring 8146
          organic mancude parent 8146
            mancude organic heterocyclic parent 8146
              mancude organic heterobicyclic parent 5230
                benzimidazole 78
                  1H-benzimidazole 76
                    1-(2,4-dichlorobenzoyl)-1H-benzimidazole 0
                    5-hydroxybenzimidazole 0
                    5-methyl-1H-benzimidazole 0
                    clemizole 10
                    mebendazole 44
                    thiabendazole 25
Path 2
Term Annotations click to browse term
  CHEBI ontology 19781
    subatomic particle 19779
      composite particle 19779
        hadron 19779
          baryon 19779
            nucleon 19779
              atomic nucleus 19779
                atom 19779
                  main group element atom 19669
                    p-block element atom 19669
                      carbon group element atom 19588
                        carbon atom 19578
                          organic molecular entity 19578
                            organic molecule 19510
                              organic cyclic compound 19337
                                organic heterocyclic compound 18550
                                  organic heteropolycyclic compound 18038
                                    organic heterobicyclic compound 16778
                                      benzimidazoles 865
                                        benzimidazole 78
                                          1H-benzimidazole 76
                                            1-(2,4-dichlorobenzoyl)-1H-benzimidazole 0
                                            5-hydroxybenzimidazole 0
                                            5-methyl-1H-benzimidazole 0
                                            clemizole 10
                                            mebendazole 44
                                            thiabendazole 25
paths to the root