Send us a Message



Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   

CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:butyrylthiocholine
go back to main search page
Accession:CHEBI:41055 term browser browse the term
Definition:A quaternary ammonium ion obtained by the formal condensation of the carboxy group of butyric acid with the thiol group of thiocholine. It is used as a reagent for determination of butyrylcholinesterase activity.
Synonyms:exact_synonym: 2-(butanoylsulfanyl)-N,N,N-trimethylethan-1-aminium
 related_synonym: Formula=C9H20NOS;   InChI=1S/C9H20NOS/c1-5-6-9(11)12-8-7-10(2,3)4/h5-8H2,1-4H3/q+1;   InChIKey=AWBGQVBMGBZGLS-UHFFFAOYSA-N;   S-butanoylthiocholine;   S-butyrylthiocholine;   SMILES=CCCC(=O)SCC[N+](C)(C)C;   butanoylthiocholine
 xref: CAS:4555-00-4;   DrugBank:DB04250
 xref_mesh: MESH:D002092
 xref: PDBeChem:BCH;   PMID:25450746;   PMID:25486543;   Reaxys:1777055



show annotations for term's descendants           Sort by:
 
butyrylthiocholine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ache acetylcholinesterase increases hydrolysis
multiple interactions
ISO ACHE protein results in increased hydrolysis of Butyrylthiocholine
huperzine A inhibits the reaction [ACHE protein results in increased hydrolysis of Butyrylthiocholine]
CTD PMID:22407886 NCBI chr12:19,407,359...19,413,713
Ensembl chr12:19,407,360...19,413,651
JBrowse link
G Bche butyrylcholinesterase multiple interactions
increases hydrolysis
increases metabolic processing
ISO
EXP
[BCHE protein results in increased metabolism of Butyrylthiocholine] which results in increased chemical synthesis of Thiocholine; butyrylcholine inhibits the reaction [BCHE protein results in increased hydrolysis of Butyrylthiocholine]; Cholinesterase Inhibitors inhibits the reaction [BCHE protein results in increased hydrolysis of Butyrylthiocholine]; Dibucaine inhibits the reaction [BCHE protein results in increased metabolism of Butyrylthiocholine]; Echothiophate Iodide inhibits the reaction [BCHE protein results in increased hydrolysis of Butyrylthiocholine]; Isoflurophate inhibits the reaction [BCHE protein results in increased hydrolysis of Butyrylthiocholine]; N,N'-monomethylenebis(pyridiniumaldoxime) inhibits the reaction [Sarin analog inhibits the reaction [BCHE protein results in increased hydrolysis of Butyrylthiocholine]]; pralidoxime inhibits the reaction [Isoflurophate inhibits the reaction [BCHE protein results in increased hydrolysis of Butyrylthiocholine]]; pralidoxime inhibits the reaction [Sarin analog inhibits the reaction [BCHE protein results in increased hydrolysis of Butyrylthiocholine]]; profenamine inhibits the reaction [BCHE protein results in increased hydrolysis of Butyrylthiocholine]; Sarin analog inhibits the reaction [BCHE protein results in increased hydrolysis of Butyrylthiocholine]; Sodium Fluoride inhibits the reaction [BCHE protein results in increased metabolism of Butyrylthiocholine] CTD PMID:19699221 PMID:21802514 PMID:22407886 PMID:22922115 PMID:22940283 More... NCBI chr 2:158,308,674...158,401,148
Ensembl chr 2:158,307,584...158,401,148
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 20072
    chemical entity 20071
      molecular entity 20071
        ion 16485
          organic ion 9208
            organic cation 8144
              quaternary ammonium ion 5131
                butyrylthiocholine 2
Path 2
Term Annotations click to browse term
  CHEBI ontology 20072
    subatomic particle 20071
      composite particle 20071
        hadron 20071
          baryon 20071
            nucleon 20071
              atomic nucleus 20071
                atom 20071
                  main group element atom 19971
                    main group molecular entity 19971
                      s-block molecular entity 19765
                        hydrogen molecular entity 19756
                          hydrides 19120
                            inorganic hydride 17878
                              pnictogen hydride 17861
                                nitrogen hydride 17747
                                  ammonium 8250
                                    ammonium ion derivative 8246
                                      quaternary ammonium ion 5131
                                        butyrylthiocholine 2
paths to the root