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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:5-benzyl-1-(2-hydroxyethoxymethyl)uracil
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Accession:CHEBI:41037 term browser browse the term
Definition:A pyrimidone that is uracil which is substituted by a 2-hydroxyethoxymethyl group at position 1 and a benzyl group at position 5.
Synonyms:exact_synonym: 5-benzyl-1-[(2-hydroxyethoxy)methyl]pyrimidine-2,4(1H,3H)-dione
 related_synonym: 5-benzylacyclouridine;   BAU;   Formula=C14H16N2O4;   InChI=1S/C14H16N2O4/c17-6-7-20-10-16-9-12(13(18)15-14(16)19)8-11-4-2-1-3-5-11/h1-5,9,17H,6-8,10H2,(H,15,18,19);   InChIKey=SPJAGILXQBHHSZ-UHFFFAOYSA-N;   SMILES=OCCOCn1cc(Cc2ccccc2)c(=O)[nH]c1=O
 xref_mesh: MESH:C034753
 xref: PDBeChem:BAU;   Reaxys:4516567



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5-benzyl-1-(2-hydroxyethoxymethyl)uracil term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Tnf tumor necrosis factor multiple interactions ISO 5-benzylacyclouridine inhibits the reaction [[TNF protein results in increased activity of UPP1 protein] which results in increased susceptibility to doxifluridine] CTD PMID:16397116 NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629
JBrowse link
G Upp1 uridine phosphorylase 1 multiple interactions ISO 5-benzylacyclouridine inhibits the reaction [[TNF protein results in increased activity of UPP1 protein] which results in increased susceptibility to doxifluridine] CTD PMID:16397116 NCBI chr14:83,809,495...83,829,299
Ensembl chr14:83,809,960...83,829,462
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19918
    role 19894
      application 19729
        pro-agent 11560
          prodrug 11319
            uracil 8026
              5-benzyl-1-(2-hydroxyethoxymethyl)uracil 2
Path 2
Term Annotations click to browse term
  CHEBI ontology 19918
    subatomic particle 19916
      composite particle 19916
        hadron 19916
          baryon 19916
            nucleon 19916
              atomic nucleus 19916
                atom 19916
                  main group element atom 19866
                    p-block element atom 19866
                      carbon group element atom 19811
                        carbon atom 19806
                          organic molecular entity 19806
                            organic molecule 19758
                              organic cyclic compound 19565
                                organic heterocyclic compound 18906
                                  organic heteromonocyclic compound 17826
                                    diazines 13238
                                      pyrimidines 13104
                                        pyrimidine nucleobase 8532
                                          uracil 8026
                                            5-benzyl-1-(2-hydroxyethoxymethyl)uracil 2
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