Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   

CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:5-benzyl-1-(2-hydroxyethoxymethyl)uracil
go back to main search page
Accession:CHEBI:41037 term browser browse the term
Definition:A pyrimidone that is uracil which is substituted by a 2-hydroxyethoxymethyl group at position 1 and a benzyl group at position 5.
Synonyms:related_synonym: 5-benzyl-1-[(2-hydroxyethoxy)methyl]pyrimidine-2,4(1H,3H)-dione;   5-benzylacyclouridine;   BAU;   Formula=C14H16N2O4;   InChI=1S/C14H16N2O4/c17-6-7-20-10-16-9-12(13(18)15-14(16)19)8-11-4-2-1-3-5-11/h1-5,9,17H,6-8,10H2,(H,15,18,19);   InChIKey=SPJAGILXQBHHSZ-UHFFFAOYSA-N;   SMILES=OCCOCn1cc(Cc2ccccc2)c(=O)[nH]c1=O
 xref_mesh: MESH:C034753
 xref: PDBeChem:BAU;   Reaxys:4516567


show annotations for term's descendants           Sort by:
 
5-benzyl-1-(2-hydroxyethoxymethyl)uracil term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Tnf tumor necrosis factor multiple interactions ISO 5-benzylacyclouridine inhibits the reaction [[TNF protein results in increased activity of UPP1 protein] which results in increased susceptibility to doxifluridine] CTD PMID:16397116 NCBI chr20:5,189,382...5,192,000
Ensembl chr20:5,189,390...5,192,000
JBrowse link
G Upp1 uridine phosphorylase 1 multiple interactions ISO 5-benzylacyclouridine inhibits the reaction [[TNF protein results in increased activity of UPP1 protein] which results in increased susceptibility to doxifluridine] CTD PMID:16397116 NCBI chr14:89,314,234...89,334,060
Ensembl chr14:89,314,176...89,334,276
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19801
    role 19747
      application 19395
        pro-agent 8828
          prodrug 8617
            uracil 5645
              5-benzyl-1-(2-hydroxyethoxymethyl)uracil 2
Path 2
Term Annotations click to browse term
  CHEBI ontology 19801
    subatomic particle 19797
      composite particle 19797
        hadron 19797
          baryon 19797
            nucleon 19797
              atomic nucleus 19797
                atom 19797
                  main group element atom 19684
                    p-block element atom 19684
                      carbon group element atom 19583
                        carbon atom 19572
                          organic molecular entity 19572
                            organic molecule 19494
                              organic cyclic compound 19264
                                organic heterocyclic compound 18431
                                  organic heteromonocyclic compound 16462
                                    diazines 12154
                                      pyrimidines 11971
                                        pyrimidine nucleobase 6091
                                          uracil 5645
                                            5-benzyl-1-(2-hydroxyethoxymethyl)uracil 2
paths to the root

NHLBI Logo

RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.