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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:cyhalothrin
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Accession:CHEBI:4035 term browser browse the term
Definition:A carboxylic ester obtained by formal condensation between 3-(2-chloro-3,3,3-trifluoroprop-1-en-1-yl)-2,2-dimethylcyclopropanecarboxylic acid and cyano(3-phenoxyphenyl)methanol.
Synonyms:exact_synonym: cyano(3-phenoxyphenyl)methyl 3-[(1Z)-2-chloro-3,3,3-trifluoroprop-1-en-1-yl]-2,2-dimethylcyclopropanecarboxylate
 related_synonym: 3-(2-Chloro-3,3,3-trifluoro-1-propenyl)-2,2-dimethylcyclopropanecarboxylic acid cyano(3-phenoxyphenyl)methyl ester;   Formula=C23H19ClF3NO3;   InChI=1S/C23H19ClF3NO3/c1-22(2)17(12-19(24)23(25,26)27)20(22)21(29)31-18(13-28)14-7-6-10-16(11-14)30-15-8-4-3-5-9-15/h3-12,17-18,20H,1-2H3/b19-12-;   InChIKey=ZXQYGBMAQZUVMI-UNOMPAQXSA-N;   SMILES=CC1(C)C(\\C=C(/Cl)C(F)(F)F)C1C(=O)OC(C#N)c1cccc(Oc2ccccc2)c1
 xref: CAS:68085-85-8;   KEGG:C10983;   KEGG:D07762
 xref_mesh: MESH:C037304
 xref: Patent:DE2802962;   Patent:US4183948


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cyhalothrin term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adh4 alcohol dehydrogenase 4 (class II), pi polypeptide increases expression EXP cyhalothrin results in increased expression of ADH4 mRNA CTD PMID:29727961 NCBI chr 2:226,948,717...226,966,747 JBrowse link
G Adh6 alcohol dehydrogenase 6 (class V) increases expression EXP cyhalothrin results in increased expression of ADH6 mRNA CTD PMID:29727961 NCBI chr 2:226,903,208...226,934,564
Ensembl chr 2:226,903,250...226,934,534
JBrowse link
G Akt1 AKT serine/threonine kinase 1 increases activity ISO cyhalothrin results in increased activity of AKT1 CTD PMID:26969072 NCBI chr 6:131,713,716...131,735,319
Ensembl chr 6:131,713,720...131,733,921
JBrowse link
G Aldh1a1 aldehyde dehydrogenase 1 family, member A1 increases expression EXP cyhalothrin results in increased expression of ALDH1A1 mRNA CTD PMID:29727961 NCBI chr 1:218,000,470...218,152,962
Ensembl chr 1:218,042,127...218,152,961
JBrowse link
G Aldh1b1 aldehyde dehydrogenase 1 family, member B1 decreases expression EXP cyhalothrin results in decreased expression of ALDH1B1 mRNA CTD PMID:29727961 NCBI chr 5:60,063,370...60,068,378
Ensembl chr 5:60,063,225...60,068,378
JBrowse link
G Aldh3b1 aldehyde dehydrogenase 3 family, member B1 increases expression EXP cyhalothrin results in increased expression of ALDH3B1 mRNA CTD PMID:29727961 NCBI chr 1:201,145,309...201,162,675
Ensembl chr 1:201,145,309...201,163,921
JBrowse link
G Ar androgen receptor decreases activity
multiple interactions
ISO
EXP
cyhalothrin results in decreased activity of AR protein
[Allethrins co-treated with cyhalothrin co-treated with cypermethrin co-treated with decamethrin co-treated with fenvalerate] results in decreased expression of AR mRNA; [cypermethrin co-treated with decamethrin co-treated with fenvalerate co-treated with cyhalothrin co-treated with Allethrins] results in increased expression of AR mRNA
cyhalothrin inhibits the reaction [Dihydrotestosterone results in increased expression of AR mRNA]
CTD PMID:20410157 PMID:21310686 PMID:33051911 PMID:33396045 NCBI chr  X:63,104,771...63,273,934
Ensembl chr  X:63,104,771...63,273,925
JBrowse link
G Bax BCL2 associated X, apoptosis regulator increases expression
multiple interactions
EXP cyhalothrin results in increased expression of BAX mRNA; cyhalothrin results in increased expression of BAX protein
[cypermethrin co-treated with decamethrin co-treated with fenvalerate co-treated with cyhalothrin co-treated with Allethrins] results in increased expression of BAX mRNA
CTD PMID:29727961 PMID:30029170 PMID:33396045 NCBI chr 1:95,940,001...95,945,407
Ensembl chr 1:95,938,808...95,945,368
JBrowse link
G Bcl2 BCL2, apoptosis regulator decreases expression
multiple interactions
EXP cyhalothrin results in decreased expression of BCL2 protein
[cypermethrin co-treated with decamethrin co-treated with fenvalerate co-treated with cyhalothrin co-treated with Allethrins] results in increased expression of BCL2 mRNA
CTD PMID:30029170 PMID:33396045 NCBI chr13:22,689,783...22,853,920 JBrowse link
G Brdt bromodomain testis associated multiple interactions EXP [Allethrins co-treated with cyhalothrin co-treated with cypermethrin co-treated with decamethrin co-treated with fenvalerate] results in decreased expression of BRDT mRNA; [cypermethrin co-treated with decamethrin co-treated with fenvalerate co-treated with cyhalothrin co-treated with Allethrins] results in decreased expression of BRDT mRNA CTD PMID:33051911 PMID:33396045 NCBI chr14:2,421,094...2,445,842
Ensembl chr14:2,387,796...2,445,842
JBrowse link
G Camk2a calcium/calmodulin-dependent protein kinase II alpha decreases expression
multiple interactions
EXP cyhalothrin results in decreased expression of CAMK2A protein
cyhalothrin promotes the reaction [NGF protein results in increased expression of CAMK2A mRNA]
CTD PMID:28385489 PMID:28487251 NCBI chr18:54,378,642...54,441,120
Ensembl chr18:54,378,784...54,438,994
JBrowse link
G Camk2b calcium/calmodulin-dependent protein kinase II beta multiple interactions EXP cyhalothrin promotes the reaction [NGF protein results in increased expression of CAMK2B mRNA] CTD PMID:28385489 NCBI chr14:80,845,206...80,934,172
Ensembl chr14:80,845,238...80,933,994
JBrowse link
G Casp3 caspase 3 increases expression EXP cyhalothrin results in increased expression of CASP3 mRNA CTD PMID:29727961 NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648
JBrowse link
G Casp9 caspase 9 multiple interactions EXP [cypermethrin co-treated with decamethrin co-treated with fenvalerate co-treated with cyhalothrin co-treated with Allethrins] results in decreased expression of CASP9 mRNA CTD PMID:33396045 NCBI chr 5:154,108,872...154,126,628
Ensembl chr 5:154,109,046...154,126,626
JBrowse link
G Cat catalase multiple interactions
decreases activity
EXP [cypermethrin co-treated with decamethrin co-treated with fenvalerate co-treated with cyhalothrin co-treated with Allethrins] affects the activity of CAT protein; thymoquinone inhibits the reaction [cyhalothrin results in decreased activity of CAT protein] CTD PMID:26645134 PMID:27348886 PMID:28058584 PMID:33396045 NCBI chr 3:89,842,393...89,874,577
Ensembl chr 3:89,842,399...89,874,478
JBrowse link
G Ccl2 C-C motif chemokine ligand 2 increases expression EXP cyhalothrin results in increased expression of CCL2 protein CTD PMID:27348886 NCBI chr10:67,005,424...67,007,222
Ensembl chr10:67,005,424...67,007,226
JBrowse link
G Ccnd1 cyclin D1 affects expression
multiple interactions
ISO cyhalothrin affects the expression of CCND1 mRNA
fulvestrant inhibits the reaction [cyhalothrin affects the expression of CCND1 mRNA]
CTD PMID:26877835 NCBI chr 1:200,089,002...200,098,524
Ensembl chr 1:200,089,002...200,098,602
JBrowse link
G Cd9 CD9 molecule multiple interactions EXP [Allethrins co-treated with cyhalothrin co-treated with cypermethrin co-treated with decamethrin co-treated with fenvalerate] results in decreased expression of CD9 mRNA; [cypermethrin co-treated with decamethrin co-treated with fenvalerate co-treated with cyhalothrin co-treated with Allethrins] results in increased expression of CD9 mRNA CTD PMID:33051911 PMID:33396045 NCBI chr 4:158,256,328...158,289,136
Ensembl chr 4:158,256,328...158,289,222
JBrowse link
G Cdk5 cyclin-dependent kinase 5 increases expression EXP cyhalothrin results in increased expression of CDK5 protein CTD PMID:28487251 NCBI chr 4:10,754,682...10,760,110
Ensembl chr 4:10,754,687...10,760,112
JBrowse link
G Ces1d carboxylesterase 1D multiple interactions
increases metabolic processing
ISO CES1 protein inhibits the reaction [cyhalothrin results in increased activity of NR1I2 protein]
CES1 protein results in increased metabolism of cyhalothrin
CTD PMID:19249324 NCBI chr19:13,873,490...13,912,035 JBrowse link
G Ciita class II, major histocompatibility complex, transactivator multiple interactions EXP [Allethrins co-treated with cyhalothrin co-treated with cypermethrin co-treated with decamethrin co-treated with fenvalerate] results in decreased expression of CIITA mRNA; [cypermethrin co-treated with decamethrin co-treated with fenvalerate co-treated with cyhalothrin co-treated with Allethrins] results in increased expression of CIITA mRNA CTD PMID:33051911 PMID:33396045 NCBI chr10:5,139,947...5,187,493
Ensembl chr10:5,140,178...5,187,440
JBrowse link
G Clu clusterin multiple interactions EXP [Allethrins co-treated with cyhalothrin co-treated with cypermethrin co-treated with decamethrin co-treated with fenvalerate] results in decreased expression of CLU mRNA CTD PMID:33051911 NCBI chr15:40,161,068...40,200,315
Ensembl chr15:40,174,617...40,200,315
JBrowse link
G Creb1 cAMP responsive element binding protein 1 decreases phosphorylation
multiple interactions
decreases expression
EXP cyhalothrin results in decreased phosphorylation of CREB1 protein
[Allethrins co-treated with cyhalothrin co-treated with cypermethrin co-treated with decamethrin co-treated with fenvalerate] results in decreased expression of CREB1 mRNA; [cypermethrin co-treated with decamethrin co-treated with fenvalerate co-treated with cyhalothrin co-treated with Allethrins] affects the expression of CREB1 mRNA
cyhalothrin results in decreased expression of CREB1 protein modified form
CTD PMID:28487251 PMID:28495607 PMID:33051911 PMID:33396045 NCBI chr 9:65,903,511...65,972,562
Ensembl chr 9:65,903,547...65,970,816
JBrowse link
G Crebbp CREB binding protein multiple interactions EXP [Allethrins co-treated with cyhalothrin co-treated with cypermethrin co-treated with decamethrin co-treated with fenvalerate] affects the expression of CREBBP mRNA; [cypermethrin co-treated with decamethrin co-treated with fenvalerate co-treated with cyhalothrin co-treated with Allethrins] results in decreased expression of CREBBP mRNA CTD PMID:33051911 PMID:33396045 NCBI chr10:11,335,551...11,461,888
Ensembl chr10:11,335,953...11,461,888
JBrowse link
G Crem cAMP responsive element modulator multiple interactions EXP [cypermethrin co-treated with decamethrin co-treated with fenvalerate co-treated with cyhalothrin co-treated with Allethrins] results in decreased expression of CREM mRNA CTD PMID:33396045 NCBI chr17:54,238,889...54,305,989
Ensembl chr17:54,239,030...54,305,989
JBrowse link
G Cybb cytochrome b-245 beta chain multiple interactions EXP [cypermethrin co-treated with decamethrin co-treated with fenvalerate co-treated with cyhalothrin co-treated with Allethrins] affects the expression of CYBB mRNA CTD PMID:33396045 NCBI chr  X:13,360,583...13,392,517
Ensembl chr  X:13,359,430...13,392,586
JBrowse link
G Cyp11a1 cytochrome P450, family 11, subfamily a, polypeptide 1 decreases expression
multiple interactions
EXP cyhalothrin results in decreased expression of CYP11A1 protein
[Allethrins co-treated with cyhalothrin co-treated with cypermethrin co-treated with decamethrin co-treated with fenvalerate] results in increased expression of CYP11A1 mRNA; [cypermethrin co-treated with decamethrin co-treated with fenvalerate co-treated with cyhalothrin co-treated with Allethrins] results in increased expression of CYP11A1 mRNA
CTD PMID:30029170 PMID:33051911 PMID:33396045 NCBI chr 8:58,422,807...58,434,342
Ensembl chr 8:58,404,669...58,434,338
JBrowse link
G Cyp17a1 cytochrome P450, family 17, subfamily a, polypeptide 1 multiple interactions EXP [Allethrins co-treated with cyhalothrin co-treated with cypermethrin co-treated with decamethrin co-treated with fenvalerate] affects the expression of CYP17A1 mRNA; [cypermethrin co-treated with decamethrin co-treated with fenvalerate co-treated with cyhalothrin co-treated with Allethrins] results in decreased expression of CYP17A1 mRNA CTD PMID:33051911 PMID:33396045 NCBI chr 1:245,535,462...245,543,148
Ensembl chr 1:245,535,462...245,541,573
JBrowse link
G Cyp19a1 cytochrome P450, family 19, subfamily a, polypeptide 1 multiple interactions EXP [Allethrins co-treated with cyhalothrin co-treated with cypermethrin co-treated with decamethrin co-treated with fenvalerate] affects the expression of CYP19A1 mRNA; [cypermethrin co-treated with decamethrin co-treated with fenvalerate co-treated with cyhalothrin co-treated with Allethrins] affects the expression of CYP19A1 mRNA CTD PMID:33051911 PMID:33396045 NCBI chr 8:54,553,165...54,580,758
Ensembl chr 8:54,553,165...54,580,758
JBrowse link
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 increases expression
increases activity
EXP cyhalothrin results in increased expression of CYP1A1 mRNA
cyhalothrin results in increased activity of CYP1A1 protein
CTD PMID:29727961 NCBI chr 8:58,096,021...58,102,130
Ensembl chr 8:58,096,077...58,102,125
JBrowse link
G Cyp1a2 cytochrome P450, family 1, subfamily a, polypeptide 2 increases activity
increases expression
ISO
EXP
cyhalothrin results in increased activity of CYP1A2 protein
cyhalothrin results in increased expression of CYP1A2 mRNA
CTD PMID:22310298 PMID:29727961 NCBI chr 8:58,075,367...58,082,255
Ensembl chr 8:58,075,367...58,082,312
JBrowse link
G Cyp26b1 cytochrome P450, family 26, subfamily b, polypeptide 1 decreases expression EXP cyhalothrin results in decreased expression of CYP26B1 mRNA CTD PMID:29727961 NCBI chr 4:117,041,808...117,058,628
Ensembl chr 4:117,041,808...117,058,628
JBrowse link
G Cyp2a1 cytochrome P450, family 2, subfamily a, polypeptide 1 increases activity
increases expression
EXP cyhalothrin results in increased activity of CYP2A1 protein
cyhalothrin results in increased expression of CYP2A1 mRNA
CTD PMID:29727961 NCBI chr 1:82,231,611...82,244,887
Ensembl chr 1:82,231,611...82,244,887
JBrowse link
G Cyp2b1 cytochrome P450, family 2, subfamily b, polypeptide 1 increases activity
increases expression
EXP cyhalothrin results in increased activity of CYP2B1 protein
cyhalothrin results in increased expression of CYP2B1 mRNA
CTD PMID:29727961 NCBI chr 1:81,518,387...81,544,999
Ensembl chr 1:81,518,408...81,542,052
JBrowse link
G Cyp2b2 cytochrome P450, family 2, subfamily b, polypeptide 2 increases expression EXP cyhalothrin results in increased expression of CYP2B2 mRNA CTD PMID:29727961 NCBI chr 1:81,594,534...81,608,567
Ensembl chr 1:81,594,555...81,608,566
JBrowse link
G Cyp2b3 cytochrome P450, family 2, subfamily b, polypeptide 3 increases activity
decreases activity
multiple interactions
increases expression
ISO cyhalothrin results in increased activity of CYP2B6 protein
cyhalothrin results in decreased activity of CYP2B6 protein
cyhalothrin inhibits the reaction [CYP2B6 protein results in increased hydroxylation of Bupropion]
cyhalothrin results in increased expression of CYP2B6 mRNA
CTD PMID:22310298 PMID:22634058 NCBI chr 1:81,652,762...81,732,153
Ensembl chr 1:81,652,787...81,732,143
JBrowse link
G Cyp2c22 cytochrome P450, family 2, subfamily c, polypeptide 22 decreases expression EXP cyhalothrin results in decreased expression of CYP2C22 mRNA CTD PMID:29727961 NCBI chr 1:238,991,698...239,031,323
Ensembl chr 1:238,991,610...239,021,738
JBrowse link
G Cyp2d4 cytochrome P450, family 2, subfamily d, polypeptide 4 decreases activity
increases expression
ISO
EXP
cyhalothrin results in decreased activity of CYP2D6 protein
cyhalothrin results in increased expression of CYP2D4 mRNA
CTD PMID:20183062 PMID:29727961 NCBI chr 7:113,882,584...113,891,754
Ensembl chr 7:113,881,618...113,891,759
JBrowse link
G Cyp2e1 cytochrome P450, family 2, subfamily e, polypeptide 1 increases expression EXP cyhalothrin results in increased expression of CYP2E1 mRNA CTD PMID:29727961 NCBI chr 1:195,840,330...195,850,728
Ensembl chr 1:195,840,058...195,864,023
JBrowse link
G Cyp2t1 cytochrome P450, family 2, subfamily t, polypeptide 1 decreases expression EXP cyhalothrin results in decreased expression of CYP2T1 mRNA CTD PMID:29727961 NCBI chr 1:82,446,321...82,451,564
Ensembl chr 1:82,446,921...82,451,563
JBrowse link
G Cyp3a18 cytochrome P450, family 3, subfamily a, polypeptide 18 increases expression EXP cyhalothrin results in increased expression of CYP3A18 mRNA CTD PMID:29727961 NCBI chr12:8,880,528...8,930,382
Ensembl chr12:8,880,528...8,930,381
JBrowse link
G Cyp3a2 cytochrome P450, family 3, subfamily a, polypeptide 2 increases expression
decreases activity
multiple interactions
increases activity
EXP
ISO
cyhalothrin results in increased expression of CYP3A2 mRNA
cyhalothrin results in decreased activity of CYP3A4 protein
[procymidone co-treated with iprodione co-treated with cyprodinil co-treated with fludioxonil co-treated with cyhalothrin] results in increased expression of CYP3A4 mRNA
cyhalothrin results in increased activity of CYP3A4 protein
cyhalothrin results in increased expression of CYP3A4 mRNA; cyhalothrin results in increased expression of CYP3A4 protein
CTD PMID:19249324 PMID:20183062 PMID:22310298 PMID:25028461 PMID:29727961 NCBI chr12:9,207,986...9,230,038
Ensembl chr12:9,015,383...9,285,008
JBrowse link
G Cyp3a23-3a1 cytochrome P450, family 3, subfamily a, polypeptide 23-polypeptide 1 increases expression EXP cyhalothrin results in increased expression of CYP3A23-3A1 mRNA CTD PMID:29727961 NCBI chr12:9,256,159...9,285,020
Ensembl chr12:9,254,475...9,285,030
JBrowse link
G Cyp4a1 cytochrome P450, family 4, subfamily a, polypeptide 1 increases expression EXP cyhalothrin results in increased expression of CYP4A1 mRNA CTD PMID:29727961 NCBI chr 5:129,123,323...129,137,464
Ensembl chr 5:129,123,336...129,137,464
JBrowse link
G Dazap1 DAZ associated protein 1 multiple interactions EXP [Allethrins co-treated with cyhalothrin co-treated with cypermethrin co-treated with decamethrin co-treated with fenvalerate] results in decreased expression of DAZAP1 mRNA; [cypermethrin co-treated with decamethrin co-treated with fenvalerate co-treated with cyhalothrin co-treated with Allethrins] results in decreased expression of DAZAP1 mRNA CTD PMID:33051911 PMID:33396045 NCBI chr 7:9,423,673...9,448,116
Ensembl chr 7:9,424,178...9,538,818
JBrowse link
G Ddx25 DEAD-box helicase 25 multiple interactions EXP [Allethrins co-treated with cyhalothrin co-treated with cypermethrin co-treated with decamethrin co-treated with fenvalerate] results in decreased expression of DDX25 mRNA; [cypermethrin co-treated with decamethrin co-treated with fenvalerate co-treated with cyhalothrin co-treated with Allethrins] results in decreased expression of DDX25 mRNA CTD PMID:33051911 PMID:33396045 NCBI chr 8:33,894,224...33,910,377
Ensembl chr 8:33,894,232...33,921,764
JBrowse link
G Ddx3 DEAD (Asp-Glu-Ala-Asp) box polypeptide 3 multiple interactions EXP [Allethrins co-treated with cyhalothrin co-treated with cypermethrin co-treated with decamethrin co-treated with fenvalerate] results in decreased expression of DDX3Y mRNA; [cypermethrin co-treated with decamethrin co-treated with fenvalerate co-treated with cyhalothrin co-treated with Allethrins] results in decreased expression of DDX3Y mRNA CTD PMID:33051911 PMID:33396045 NCBI chr  Y:1,115,095...1,135,754
Ensembl chr  Y:1,116,309...1,135,706
JBrowse link
G Dlg4 discs large MAGUK scaffold protein 4 multiple interactions
decreases expression
increases expression
ISO
EXP
2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [cyhalothrin results in increased expression of DLG4]; cyhalothrin inhibits the reaction [Estradiol results in increased expression of DLG4 protein]; fulvestrant inhibits the reaction [cyhalothrin results in increased expression of DLG4 protein]
cyhalothrin results in decreased expression of DLG4 protein
CTD PMID:26969072 PMID:28487251 NCBI chr10:54,740,700...54,769,097
Ensembl chr10:54,739,470...54,767,153
JBrowse link
G Dnmt1 DNA methyltransferase 1 multiple interactions EXP [Allethrins co-treated with cyhalothrin co-treated with cypermethrin co-treated with decamethrin co-treated with fenvalerate] affects the expression of DNMT1 mRNA CTD PMID:33051911 NCBI chr 8:19,440,611...19,486,659
Ensembl chr 8:19,440,611...19,486,659
JBrowse link
G Dnmt3a DNA methyltransferase 3 alpha multiple interactions EXP [Allethrins co-treated with cyhalothrin co-treated with cypermethrin co-treated with decamethrin co-treated with fenvalerate] results in decreased expression of DNMT3A mRNA; [cypermethrin co-treated with decamethrin co-treated with fenvalerate co-treated with cyhalothrin co-treated with Allethrins] results in decreased expression of DNMT3A mRNA CTD PMID:33051911 PMID:33396045 NCBI chr 6:26,791,517...26,902,161
Ensembl chr 6:26,822,609...26,896,687
JBrowse link
G Dnmt3b DNA methyltransferase 3 beta multiple interactions EXP [Allethrins co-treated with cyhalothrin co-treated with cypermethrin co-treated with decamethrin co-treated with fenvalerate] results in decreased expression of DNMT3B mRNA; [cypermethrin co-treated with decamethrin co-treated with fenvalerate co-treated with cyhalothrin co-treated with Allethrins] results in increased expression of DNMT3B mRNA CTD PMID:33051911 PMID:33396045 NCBI chr 3:142,130,592...142,169,124
Ensembl chr 3:142,130,592...142,169,124
JBrowse link
G Drd2 dopamine receptor D2 decreases expression EXP cyhalothrin results in decreased expression of DRD2 mRNA; cyhalothrin results in decreased expression of DRD2 protein CTD PMID:22366556 PMID:28495607 NCBI chr 8:49,708,903...49,772,888
Ensembl chr 8:49,708,927...49,772,875
JBrowse link
G Eif4ebp1 eukaryotic translation initiation factor 4E binding protein 1 increases activity ISO cyhalothrin results in increased activity of EIF4EBP1 CTD PMID:26969072 NCBI chr16:64,792,595...64,805,984
Ensembl chr16:64,790,226...64,805,984
JBrowse link
G Entpd1 ectonucleoside triphosphate diphosphohydrolase 1 increases expression EXP cyhalothrin results in increased expression of ENTPD1 mRNA CTD PMID:31421116 NCBI chr 1:239,425,515...239,552,323
Ensembl chr 1:239,425,430...239,552,317
JBrowse link
G Entpd2 ectonucleoside triphosphate diphosphohydrolase 2 increases expression EXP cyhalothrin results in increased expression of ENTPD2 mRNA CTD PMID:31421116 NCBI chr 3:8,213,575...8,219,094
Ensembl chr 3:8,213,663...8,226,866
JBrowse link
G Entpd3 ectonucleoside triphosphate diphosphohydrolase 3 increases expression EXP cyhalothrin results in increased expression of ENTPD3 mRNA CTD PMID:31421116 NCBI chr 8:120,246,412...120,277,943
Ensembl chr 8:120,247,121...120,277,943
JBrowse link
G Ep300 E1A binding protein p300 multiple interactions EXP [Allethrins co-treated with cyhalothrin co-treated with cypermethrin co-treated with decamethrin co-treated with fenvalerate] affects the expression of EP300 mRNA; [cypermethrin co-treated with decamethrin co-treated with fenvalerate co-treated with cyhalothrin co-treated with Allethrins] results in decreased expression of EP300 mRNA CTD PMID:33051911 PMID:33396045 NCBI chr 7:113,108,476...113,178,529
Ensembl chr 7:113,106,247...113,136,088
JBrowse link
G Erbb2 erb-b2 receptor tyrosine kinase 2 affects binding ISO cyhalothrin binds to ERBB2 protein CTD PMID:32278787 NCBI chr10:83,411,197...83,435,078
Ensembl chr10:83,411,313...83,435,078
JBrowse link
G Esr1 estrogen receptor 1 increases activity
increases expression
multiple interactions
decreases expression
EXP
ISO
cyhalothrin results in increased activity of ESR1 protein
cyhalothrin results in increased expression of ESR1
2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [cyhalothrin results in increased expression of ESR1]; fulvestrant inhibits the reaction [cyhalothrin results in increased expression of ESR1]
cyhalothrin results in decreased expression of ESR1 mRNA; cyhalothrin results in decreased expression of ESR1 protein
CTD PMID:18419197 PMID:20097460 PMID:20410157 PMID:26969072 NCBI chr 1:41,106,335...41,499,104
Ensembl chr 1:41,210,475...41,495,002
JBrowse link
G Esr2 estrogen receptor 2 decreases expression ISO cyhalothrin results in decreased expression of ESR2 mRNA; cyhalothrin results in decreased expression of ESR2 protein CTD PMID:18419197 NCBI chr 6:94,858,438...94,909,630
Ensembl chr 6:94,809,547...94,908,919
JBrowse link
G Ezh2 enhancer of zeste 2 polycomb repressive complex 2 subunit multiple interactions EXP [Allethrins co-treated with cyhalothrin co-treated with cypermethrin co-treated with decamethrin co-treated with fenvalerate] results in increased expression of EZH2 mRNA; [cypermethrin co-treated with decamethrin co-treated with fenvalerate co-treated with cyhalothrin co-treated with Allethrins] affects the expression of EZH2 mRNA CTD PMID:33051911 PMID:33396045 NCBI chr 4:76,624,399...76,687,362
Ensembl chr 4:76,624,399...76,687,362
JBrowse link
G Fasn fatty acid synthase increases expression EXP cyhalothrin results in increased expression of FASN mRNA; cyhalothrin results in increased expression of FASN protein CTD PMID:27348886 NCBI chr10:106,072,093...106,090,259
Ensembl chr10:106,072,091...106,090,261
JBrowse link
G Fgfr2 fibroblast growth factor receptor 2 affects binding ISO cyhalothrin binds to FGFR2 protein CTD PMID:32278787 NCBI chr 1:184,745,418...184,850,655
Ensembl chr 1:184,745,420...184,850,626
JBrowse link
G Fmo5 flavin containing dimethylaniline monoxygenase 5 increases expression EXP cyhalothrin results in increased expression of FMO5 mRNA CTD PMID:29727961 NCBI chr 2:185,197,184...185,249,699
Ensembl chr 2:185,222,204...185,249,693
JBrowse link
G Fshb follicle stimulating hormone subunit beta decreases expression
increases expression
multiple interactions
EXP cyhalothrin results in decreased expression of FSHB protein
cyhalothrin results in increased expression of FSHB protein
Taurine inhibits the reaction [cyhalothrin results in decreased expression of FSHB protein]
CTD PMID:29506456 PMID:30029170 NCBI chr 3:93,548,560...93,552,370
Ensembl chr 3:93,548,560...93,552,370
JBrowse link
G Fshr follicle stimulating hormone receptor multiple interactions EXP [Allethrins co-treated with cyhalothrin co-treated with cypermethrin co-treated with decamethrin co-treated with fenvalerate] affects the expression of FSHR mRNA; [cypermethrin co-treated with decamethrin co-treated with fenvalerate co-treated with cyhalothrin co-treated with Allethrins] results in increased expression of FSHR mRNA CTD PMID:33051911 PMID:33396045 NCBI chr 6:5,198,825...5,406,785
Ensembl chr 6:5,198,825...5,406,785
JBrowse link
G Gap43 growth associated protein 43 multiple interactions EXP cyhalothrin promotes the reaction [NGF protein results in increased expression of GAP43 mRNA] CTD PMID:28385489 NCBI chr11:58,376,371...58,470,047
Ensembl chr11:58,376,371...58,470,045
JBrowse link
G Gata4 GATA binding protein 4 multiple interactions EXP [Allethrins co-treated with cyhalothrin co-treated with cypermethrin co-treated with decamethrin co-treated with fenvalerate] affects the expression of GATA4 mRNA CTD PMID:33051911 NCBI chr15:37,459,601...37,531,291
Ensembl chr15:37,459,601...37,505,636
JBrowse link
G Gdnf glial cell derived neurotrophic factor multiple interactions EXP [Allethrins co-treated with cyhalothrin co-treated with cypermethrin co-treated with decamethrin co-treated with fenvalerate] results in decreased expression of GDNF mRNA; [cypermethrin co-treated with decamethrin co-treated with fenvalerate co-treated with cyhalothrin co-treated with Allethrins] results in increased expression of GDNF mRNA CTD PMID:33051911 PMID:33396045 NCBI chr 2:56,893,992...56,919,935
Ensembl chr 2:56,895,010...56,917,209
JBrowse link
G Gfra1 GDNF family receptor alpha 1 multiple interactions EXP [Allethrins co-treated with cyhalothrin co-treated with cypermethrin co-treated with decamethrin co-treated with fenvalerate] results in decreased expression of GFRA1 mRNA; [cypermethrin co-treated with decamethrin co-treated with fenvalerate co-treated with cyhalothrin co-treated with Allethrins] results in decreased expression of GFRA1 mRNA CTD PMID:33051911 PMID:33396045 NCBI chr 1:257,315,682...257,552,004 JBrowse link
G Gpt glutamic--pyruvic transaminase increases activity
multiple interactions
EXP cyhalothrin results in increased activity of GPT protein
[cypermethrin co-treated with decamethrin co-treated with fenvalerate co-treated with cyhalothrin co-treated with Allethrins] results in increased activity of GPT protein
CTD PMID:28058584 PMID:33396045 NCBI chr 7:108,416,646...108,419,495
Ensembl chr 7:108,416,642...108,419,494
JBrowse link
G Grin1 glutamate ionotropic receptor NMDA type subunit 1 decreases expression EXP cyhalothrin results in decreased expression of GRIN1 mRNA; cyhalothrin results in decreased expression of GRIN1 protein CTD PMID:28487251 NCBI chr 3:8,103,680...8,130,603
Ensembl chr 3:8,103,680...8,130,603
JBrowse link
G Grin2b glutamate ionotropic receptor NMDA type subunit 2B decreases expression EXP cyhalothrin results in decreased expression of GRIN2B mRNA; cyhalothrin results in decreased expression of GRIN2B protein CTD PMID:28487251 NCBI chr 4:168,580,824...169,044,110
Ensembl chr 4:168,599,546...169,042,279
JBrowse link
G Gsr glutathione-disulfide reductase increases activity EXP cyhalothrin results in increased activity of GSR protein CTD PMID:29727961 NCBI chr16:58,482,209...58,525,256
Ensembl chr16:58,482,505...58,525,661
JBrowse link
G H2ax H2A.X variant histone multiple interactions ISO [fludioxonil co-treated with cyprodinil co-treated with procymidone co-treated with iprodione co-treated with cyhalothrin] results in increased phosphorylation of H2AX protein CTD PMID:22389207 NCBI chr 8:44,671,927...44,673,257
Ensembl chr 8:44,671,786...44,673,239
JBrowse link
G Hdac1 histone deacetylase 1 multiple interactions EXP [Allethrins co-treated with cyhalothrin co-treated with cypermethrin co-treated with decamethrin co-treated with fenvalerate] affects the expression of HDAC1 mRNA; [cypermethrin co-treated with decamethrin co-treated with fenvalerate co-treated with cyhalothrin co-treated with Allethrins] results in decreased expression of HDAC1 mRNA CTD PMID:33051911 PMID:33396045 NCBI chr 5:141,853,992...141,881,057
Ensembl chr 5:141,853,989...141,881,111
JBrowse link
G Hdac10 histone deacetylase 10 multiple interactions EXP [Allethrins co-treated with cyhalothrin co-treated with cypermethrin co-treated with decamethrin co-treated with fenvalerate] affects the expression of HDAC10 mRNA; [cypermethrin co-treated with decamethrin co-treated with fenvalerate co-treated with cyhalothrin co-treated with Allethrins] results in decreased expression of HDAC10 mRNA CTD PMID:33051911 PMID:33396045 NCBI chr 7:120,199,126...120,205,850
Ensembl chr 7:120,199,129...120,204,228
JBrowse link
G Hdac4 histone deacetylase 4 multiple interactions EXP [Allethrins co-treated with cyhalothrin co-treated with cypermethrin co-treated with decamethrin co-treated with fenvalerate] affects the expression of HDAC4 mRNA; [cypermethrin co-treated with decamethrin co-treated with fenvalerate co-treated with cyhalothrin co-treated with Allethrins] affects the expression of HDAC4 mRNA CTD PMID:33051911 PMID:33396045 NCBI chr 9:92,503,467...92,750,164
Ensembl chr 9:92,507,611...92,750,164
JBrowse link
G Hif1a hypoxia inducible factor 1 subunit alpha multiple interactions EXP [cypermethrin co-treated with decamethrin co-treated with fenvalerate co-treated with cyhalothrin co-treated with Allethrins] results in decreased expression of HIF1A mRNA CTD PMID:33396045 NCBI chr 6:92,624,059...92,669,262
Ensembl chr 6:92,624,390...92,669,261
JBrowse link
G Hmgcr 3-hydroxy-3-methylglutaryl-CoA reductase multiple interactions EXP [Allethrins co-treated with cyhalothrin co-treated with cypermethrin co-treated with decamethrin co-treated with fenvalerate] results in decreased expression of HMGCR mRNA; [cypermethrin co-treated with decamethrin co-treated with fenvalerate co-treated with cyhalothrin co-treated with Allethrins] results in decreased expression of HMGCR mRNA CTD PMID:33051911 PMID:33396045 NCBI chr 2:27,997,523...28,018,983
Ensembl chr 2:27,997,525...28,019,703
JBrowse link
G Hmgcs1 3-hydroxy-3-methylglutaryl-CoA synthase 1 multiple interactions EXP [Allethrins co-treated with cyhalothrin co-treated with cypermethrin co-treated with decamethrin co-treated with fenvalerate] results in decreased expression of HMGCS1 mRNA; [cypermethrin co-treated with decamethrin co-treated with fenvalerate co-treated with cyhalothrin co-treated with Allethrins] results in decreased expression of HMGCS1 mRNA CTD PMID:33051911 PMID:33396045 NCBI chr 2:51,649,368...51,667,100
Ensembl chr 2:51,649,497...51,667,100
JBrowse link
G Hmox1 heme oxygenase 1 multiple interactions EXP [cypermethrin co-treated with decamethrin co-treated with fenvalerate co-treated with cyhalothrin co-treated with Allethrins] results in decreased expression of HMOX1 mRNA CTD PMID:33396045 NCBI chr19:13,466,287...13,474,082
Ensembl chr19:13,467,244...13,474,079
JBrowse link
G Hp1bp3 heterochromatin protein 1, binding protein 3 multiple interactions EXP [Allethrins co-treated with cyhalothrin co-treated with cypermethrin co-treated with decamethrin co-treated with fenvalerate] results in decreased expression of HP1BP3 mRNA; [cypermethrin co-treated with decamethrin co-treated with fenvalerate co-treated with cyhalothrin co-treated with Allethrins] results in decreased expression of HP1BP3 mRNA CTD PMID:33051911 PMID:33396045 NCBI chr 5:150,435,781...150,463,004
Ensembl chr 5:150,433,740...150,463,000
JBrowse link
G Hprt1 hypoxanthine phosphoribosyltransferase 1 increases expression EXP cyhalothrin results in increased expression of HPRT1 mRNA CTD PMID:29727961 NCBI chr  X:132,736,175...132,768,149
Ensembl chr  X:132,736,096...132,768,154
JBrowse link
G Hsd11b1 hydroxysteroid 11-beta dehydrogenase 1 decreases expression EXP cyhalothrin results in decreased expression of HSD11B1 mRNA; cyhalothrin results in decreased expression of HSD11B1 protein CTD PMID:30029170 NCBI chr13:104,728,539...104,798,884
Ensembl chr13:104,728,539...104,788,687
JBrowse link
G Hsd17b3 hydroxysteroid (17-beta) dehydrogenase 3 decreases expression
multiple interactions
EXP cyhalothrin results in decreased expression of HSD17B3 mRNA
[Allethrins co-treated with cyhalothrin co-treated with cypermethrin co-treated with decamethrin co-treated with fenvalerate] results in decreased expression of HSD17B3 mRNA; [cypermethrin co-treated with decamethrin co-treated with fenvalerate co-treated with cyhalothrin co-treated with Allethrins] affects the expression of HSD17B3 mRNA; Taurine inhibits the reaction [cyhalothrin results in decreased expression of HSD17B3 mRNA]
CTD PMID:29506456 PMID:33051911 PMID:33396045 NCBI chr17:1,027,229...1,058,554
Ensembl chr17:1,027,229...1,058,554
JBrowse link
G Hsd3b1 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1 decreases expression
multiple interactions
EXP cyhalothrin results in decreased expression of HSD3B1 mRNA; cyhalothrin results in decreased expression of HSD3B1 protein
[Allethrins co-treated with cyhalothrin co-treated with cypermethrin co-treated with decamethrin co-treated with fenvalerate] affects the expression of HSD3B1 mRNA; [cypermethrin co-treated with decamethrin co-treated with fenvalerate co-treated with cyhalothrin co-treated with Allethrins] results in increased expression of HSD3B1 mRNA
CTD PMID:30029170 PMID:33051911 PMID:33396045 NCBI chr 2:186,169,864...186,175,984
Ensembl chr 2:186,169,863...186,175,999
JBrowse link
G Hsf2 heat shock transcription factor 2 multiple interactions EXP [Allethrins co-treated with cyhalothrin co-treated with cypermethrin co-treated with decamethrin co-treated with fenvalerate] results in decreased expression of HSF2 mRNA; [cypermethrin co-treated with decamethrin co-treated with fenvalerate co-treated with cyhalothrin co-treated with Allethrins] results in decreased expression of HSF2 mRNA CTD PMID:33051911 PMID:33396045 NCBI chr20:36,819,864...36,847,490
Ensembl chr20:36,819,864...36,850,174
JBrowse link
G Htr2a 5-hydroxytryptamine receptor 2A increases expression EXP cyhalothrin results in increased expression of HTR2A protein CTD PMID:22366556 NCBI chr15:49,950,035...50,022,188
Ensembl chr15:49,950,804...50,020,928
JBrowse link
G Ifng interferon gamma increases expression
multiple interactions
EXP cyhalothrin results in increased expression of IFNG mRNA; cyhalothrin results in increased expression of IFNG protein
thymoquinone inhibits the reaction [cyhalothrin results in increased expression of IFNG mRNA]; thymoquinone inhibits the reaction [cyhalothrin results in increased expression of IFNG protein]
CTD PMID:26645134 NCBI chr 7:53,903,339...53,907,375
Ensembl chr 7:53,903,337...53,907,375
JBrowse link
G Il10 interleukin 10 multiple interactions
decreases expression
EXP thymoquinone inhibits the reaction [cyhalothrin results in decreased expression of IL10 mRNA]; thymoquinone inhibits the reaction [cyhalothrin results in decreased expression of IL10 protein]
cyhalothrin results in decreased expression of IL10 mRNA; cyhalothrin results in decreased expression of IL10 protein
CTD PMID:26645134 NCBI chr13:42,472,625...42,477,308
Ensembl chr13:42,472,839...42,477,313
JBrowse link
G Il1b interleukin 1 beta multiple interactions
increases expression
EXP thymoquinone inhibits the reaction [cyhalothrin results in increased expression of IL1B mRNA]; thymoquinone inhibits the reaction [cyhalothrin results in increased expression of IL1B protein]
cyhalothrin results in increased expression of IL1B mRNA; cyhalothrin results in increased expression of IL1B protein
CTD PMID:26645134 PMID:28058584 NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415
JBrowse link
G Il4 interleukin 4 multiple interactions
decreases expression
EXP thymoquinone inhibits the reaction [cyhalothrin results in decreased expression of IL4 mRNA]; thymoquinone inhibits the reaction [cyhalothrin results in decreased expression of IL4 protein]
cyhalothrin results in decreased expression of IL4 mRNA; cyhalothrin results in decreased expression of IL4 protein
CTD PMID:26645134 NCBI chr10:37,771,203...37,776,750
Ensembl chr10:37,771,203...37,776,750
JBrowse link
G Il6 interleukin 6 multiple interactions
increases expression
EXP thymoquinone inhibits the reaction [cyhalothrin results in increased expression of IL6 mRNA]; thymoquinone inhibits the reaction [cyhalothrin results in increased expression of IL6 protein]
cyhalothrin results in increased expression of IL6 mRNA; cyhalothrin results in increased expression of IL6 protein
CTD PMID:26645134 PMID:28058584 NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178
JBrowse link
G Inhba inhibin subunit beta A multiple interactions EXP [Allethrins co-treated with cyhalothrin co-treated with cypermethrin co-treated with decamethrin co-treated with fenvalerate] results in decreased expression of INHBA mRNA; [cypermethrin co-treated with decamethrin co-treated with fenvalerate co-treated with cyhalothrin co-treated with Allethrins] affects the expression of INHBA mRNA CTD PMID:33051911 PMID:33396045 NCBI chr17:49,091,635...49,111,573
Ensembl chr17:49,095,920...49,108,982
JBrowse link
G Kitlg KIT ligand multiple interactions EXP [Allethrins co-treated with cyhalothrin co-treated with cypermethrin co-treated with decamethrin co-treated with fenvalerate] results in decreased expression of KITLG mRNA; [cypermethrin co-treated with decamethrin co-treated with fenvalerate co-treated with cyhalothrin co-treated with Allethrins] results in increased expression of KITLG mRNA CTD PMID:33051911 PMID:33396045 NCBI chr 7:34,896,075...34,977,215
Ensembl chr 7:34,896,053...34,977,214
JBrowse link
G Klf4 Kruppel like factor 4 multiple interactions EXP [cypermethrin co-treated with decamethrin co-treated with fenvalerate co-treated with cyhalothrin co-treated with Allethrins] results in decreased expression of KLF4 mRNA CTD PMID:33396045 NCBI chr 5:70,278,843...70,283,751
Ensembl chr 5:70,278,972...70,283,602
JBrowse link
G Lep leptin increases expression EXP cyhalothrin results in increased expression of LEP protein CTD PMID:27348886 NCBI chr 4:57,661,127...57,675,262
Ensembl chr 4:57,661,131...57,675,262
JBrowse link
G Lhb luteinizing hormone subunit beta multiple interactions
decreases expression
EXP Taurine inhibits the reaction [cyhalothrin results in decreased expression of LHB protein] CTD PMID:29506456 PMID:30029170 NCBI chr 1:95,898,269...95,901,973
Ensembl chr 1:95,900,984...95,901,972
Ensembl chr 1:95,900,984...95,901,972
JBrowse link
G Lhcgr luteinizing hormone/choriogonadotropin receptor multiple interactions EXP [Allethrins co-treated with cyhalothrin co-treated with cypermethrin co-treated with decamethrin co-treated with fenvalerate] affects the expression of LHCGR mRNA; [cypermethrin co-treated with decamethrin co-treated with fenvalerate co-treated with cyhalothrin co-treated with Allethrins] results in increased expression of LHCGR mRNA CTD PMID:33051911 PMID:33396045 NCBI chr 6:5,661,871...5,728,109
Ensembl chr 6:5,661,871...5,724,521
JBrowse link
G Mapk1 mitogen activated protein kinase 1 decreases expression EXP cyhalothrin results in decreased expression of MAPK1 protein modified form CTD PMID:28487251 NCBI chr11:83,957,813...84,023,629
Ensembl chr11:83,957,813...84,023,616
JBrowse link
G Mapk3 mitogen activated protein kinase 3 decreases expression EXP cyhalothrin results in decreased expression of MAPK3 protein modified form CTD PMID:28487251 NCBI chr 1:181,366,646...181,372,863
Ensembl chr 1:181,366,637...181,372,863
JBrowse link
G Mmp9 matrix metallopeptidase 9 affects binding ISO cyhalothrin binds to MMP9 protein CTD PMID:32278787 NCBI chr 3:153,684,158...153,692,118
Ensembl chr 3:153,683,858...153,692,120
JBrowse link
G Ncoa7 nuclear receptor coactivator 7 multiple interactions EXP [Allethrins co-treated with cyhalothrin co-treated with cypermethrin co-treated with decamethrin co-treated with fenvalerate] results in decreased expression of NCOA7 mRNA; [cypermethrin co-treated with decamethrin co-treated with fenvalerate co-treated with cyhalothrin co-treated with Allethrins] results in decreased expression of NCOA7 mRNA CTD PMID:33051911 PMID:33396045 NCBI chr 1:26,856,228...27,016,950
Ensembl chr 1:26,856,530...27,015,871
JBrowse link
G Nfe2l2 nuclear factor, erythroid 2-like 2 multiple interactions EXP [cypermethrin co-treated with decamethrin co-treated with fenvalerate co-treated with cyhalothrin co-treated with Allethrins] results in decreased expression of NFE2L2 mRNA CTD PMID:33396045 NCBI chr 3:60,594,239...60,621,785
Ensembl chr 3:60,594,242...60,621,737
JBrowse link
G Ngf nerve growth factor multiple interactions EXP cyhalothrin promotes the reaction [NGF protein results in decreased expression of TUBA3A mRNA]; cyhalothrin promotes the reaction [NGF protein results in increased expression of CAMK2A mRNA]; cyhalothrin promotes the reaction [NGF protein results in increased expression of CAMK2B mRNA]; cyhalothrin promotes the reaction [NGF protein results in increased expression of GAP43 mRNA]; cyhalothrin promotes the reaction [NGF protein results in increased expression of TUBB3 mRNA] CTD PMID:28385489 NCBI chr 2:189,901,058...189,954,452
Ensembl chr 2:189,901,058...189,954,452
JBrowse link
G Nqo1 NAD(P)H quinone dehydrogenase 1 multiple interactions EXP [cypermethrin co-treated with decamethrin co-treated with fenvalerate co-treated with cyhalothrin co-treated with Allethrins] results in decreased expression of NQO1 mRNA CTD PMID:33396045 NCBI chr19:35,295,633...35,310,528
Ensembl chr19:35,295,573...35,310,557
JBrowse link
G Nr0b1 nuclear receptor subfamily 0, group B, member 1 multiple interactions EXP [Allethrins co-treated with cyhalothrin co-treated with cypermethrin co-treated with decamethrin co-treated with fenvalerate] results in decreased expression of NR0B1 mRNA; [cypermethrin co-treated with decamethrin co-treated with fenvalerate co-treated with cyhalothrin co-treated with Allethrins] results in increased expression of NR0B1 mRNA CTD PMID:33051911 PMID:33396045 NCBI chr  X:50,756,886...50,761,014
Ensembl chr  X:50,756,886...50,761,011
JBrowse link
G Nr1h4 nuclear receptor subfamily 1, group H, member 4 multiple interactions ISO cyhalothrin inhibits the reaction [pregna-4,17-diene-3,16-dione results in decreased activity of NR1H4 protein] CTD PMID:25257666 NCBI chr 7:23,846,122...23,942,085
Ensembl chr 7:23,846,122...23,942,047
JBrowse link
G Nr1i2 nuclear receptor subfamily 1, group I, member 2 increases activity
multiple interactions
ISO
EXP
cyhalothrin results in increased activity of NR1I2 protein; cyhalothrin results in increased activity of NR1I2 protein polymorphism
[procymidone co-treated with iprodione co-treated with cyprodinil co-treated with fludioxonil co-treated with cyhalothrin] results in increased activity of NR1I2 protein; CES1 protein inhibits the reaction [cyhalothrin results in increased activity of NR1I2 protein]; cyhalothrin binds to and results in increased activity of NR1I2 protein
CTD PMID:19249324 PMID:21115097 PMID:25028461 NCBI chr11:62,460,213...62,496,665
Ensembl chr11:62,460,213...62,496,658
JBrowse link
G Nr3c1 nuclear receptor subfamily 3, group C, member 1 multiple interactions ISO cyhalothrin inhibits the reaction [Hydrocortisone results in increased activity of NR3C1 protein] CTD PMID:26647222 NCBI chr18:31,271,681...31,393,320
Ensembl chr18:31,271,681...31,393,375
JBrowse link
G Nr5a1 nuclear receptor subfamily 5, group A, member 1 multiple interactions EXP [cypermethrin co-treated with decamethrin co-treated with fenvalerate co-treated with cyhalothrin co-treated with Allethrins] affects the expression of NR5A1 mRNA CTD PMID:33396045 NCBI chr 3:22,464,786...22,486,328
Ensembl chr 3:22,465,502...22,486,328
JBrowse link
G Ovol1 ovo like transcriptional repressor 1 multiple interactions EXP [Allethrins co-treated with cyhalothrin co-treated with cypermethrin co-treated with decamethrin co-treated with fenvalerate] results in decreased expression of OVOL1 mRNA; [cypermethrin co-treated with decamethrin co-treated with fenvalerate co-treated with cyhalothrin co-treated with Allethrins] results in decreased expression of OVOL1 mRNA CTD PMID:33051911 PMID:33396045 NCBI chr 1:202,855,261...202,868,858
Ensembl chr 1:202,855,265...202,866,831
JBrowse link
G Pcna proliferating cell nuclear antigen multiple interactions EXP [Allethrins co-treated with cyhalothrin co-treated with cypermethrin co-treated with decamethrin co-treated with fenvalerate] affects the expression of PCNA mRNA; [cypermethrin co-treated with decamethrin co-treated with fenvalerate co-treated with cyhalothrin co-treated with Allethrins] results in decreased expression of PCNA mRNA CTD PMID:33051911 PMID:33396045 NCBI chr 3:119,499,039...119,502,911
Ensembl chr 3:119,498,810...119,502,995
JBrowse link
G Pde4b phosphodiesterase 4B multiple interactions EXP [Allethrins co-treated with cyhalothrin co-treated with cypermethrin co-treated with decamethrin co-treated with fenvalerate] results in decreased expression of PDE4B mRNA; [cypermethrin co-treated with decamethrin co-treated with fenvalerate co-treated with cyhalothrin co-treated with Allethrins] results in decreased expression of PDE4B mRNA CTD PMID:33051911 PMID:33396045 NCBI chr 5:116,799,827...117,367,707
Ensembl chr 5:116,799,971...117,367,696
JBrowse link
G Pgr progesterone receptor increases expression
affects binding
ISO cyhalothrin results in increased expression of PGR mRNA
cyhalothrin binds to PGR protein
CTD PMID:18419197 PMID:32278787 NCBI chr 8:6,073,216...6,131,552
Ensembl chr 8:6,072,673...6,131,344
JBrowse link
G Pik3cg phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit gamma affects binding ISO cyhalothrin binds to PIK3CG protein CTD PMID:32278787 NCBI chr 6:48,766,778...48,802,098
Ensembl chr 6:48,766,864...48,802,043
JBrowse link
G Ppara peroxisome proliferator activated receptor alpha increases expression EXP cyhalothrin results in increased expression of PPARA mRNA CTD PMID:27348886 NCBI chr 7:116,832,405...116,900,878
Ensembl chr 7:116,832,756...116,895,346
JBrowse link
G Pparg peroxisome proliferator-activated receptor gamma increases expression EXP cyhalothrin results in increased expression of PPARG mRNA CTD PMID:27348886 NCBI chr 4:148,423,102...148,548,471
Ensembl chr 4:148,423,194...148,548,468
JBrowse link
G Ppp1ca protein phosphatase 1 catalytic subunit alpha increases expression EXP cyhalothrin results in increased expression of PPP1CA protein CTD PMID:28495607 NCBI chr 1:201,485,117...201,488,734
Ensembl chr 1:201,485,085...201,497,327
JBrowse link
G Ppp1r1b protein phosphatase 1, regulatory (inhibitor) subunit 1B decreases expression EXP cyhalothrin results in decreased expression of PPP1R1B protein CTD PMID:28495607 NCBI chr10:83,347,731...83,356,775
Ensembl chr10:83,347,731...83,356,775
JBrowse link
G Prm1 protamine 1 multiple interactions EXP [Allethrins co-treated with cyhalothrin co-treated with cypermethrin co-treated with decamethrin co-treated with fenvalerate] results in decreased expression of PRM1 mRNA; [cypermethrin co-treated with decamethrin co-treated with fenvalerate co-treated with cyhalothrin co-treated with Allethrins] affects the expression of PRM1 mRNA CTD PMID:33051911 PMID:33396045 NCBI chr10:4,871,909...4,872,155 JBrowse link
G Prm2 protamine 2 multiple interactions EXP [cypermethrin co-treated with decamethrin co-treated with fenvalerate co-treated with cyhalothrin co-treated with Allethrins] results in decreased expression of PRM2 mRNA CTD PMID:33396045 NCBI chr10:4,876,398...4,876,834
Ensembl chr10:4,873,372...4,877,026
JBrowse link
G Pygo2 pygopus family PHD finger 2 multiple interactions EXP [Allethrins co-treated with cyhalothrin co-treated with cypermethrin co-treated with decamethrin co-treated with fenvalerate] results in decreased expression of PYGO2 mRNA; [cypermethrin co-treated with decamethrin co-treated with fenvalerate co-treated with cyhalothrin co-treated with Allethrins] results in decreased expression of PYGO2 mRNA CTD PMID:33051911 PMID:33396045 NCBI chr 2:174,849,670...174,854,758
Ensembl chr 2:174,849,936...174,854,758
JBrowse link
G Rela RELA proto-oncogene, NF-kB subunit increases expression
multiple interactions
EXP cyhalothrin results in increased expression of RELA mRNA
thymoquinone inhibits the reaction [cyhalothrin results in increased expression of RELA mRNA]
CTD PMID:26645134 NCBI chr 1:202,925,001...202,935,484
Ensembl chr 1:202,924,945...202,935,484
JBrowse link
G Rora RAR-related orphan receptor A affects binding ISO cyhalothrin binds to RORA protein CTD PMID:32278787 NCBI chr 8:69,301,635...70,034,741
Ensembl chr 8:69,301,733...70,025,931
JBrowse link
G Rorc RAR-related orphan receptor C affects binding ISO cyhalothrin binds to RORC protein CTD PMID:32278787 NCBI chr 2:182,009,707...182,034,910
Ensembl chr 2:182,009,286...182,034,907
JBrowse link
G Rplp1 ribosomal protein lateral stalk subunit P1 increases expression EXP cyhalothrin results in increased expression of RPLP1 mRNA CTD PMID:29727961 NCBI chr 8:62,394,008...62,395,341
Ensembl chr 8:62,393,177...62,395,339
JBrowse link
G Scarb1 scavenger receptor class B, member 1 decreases expression
multiple interactions
EXP cyhalothrin results in decreased expression of SCARB1 mRNA; cyhalothrin results in decreased expression of SCARB1 protein
[Allethrins co-treated with cyhalothrin co-treated with cypermethrin co-treated with decamethrin co-treated with fenvalerate] results in decreased expression of SCARB1 mRNA; [cypermethrin co-treated with decamethrin co-treated with fenvalerate co-treated with cyhalothrin co-treated with Allethrins] results in increased expression of SCARB1 mRNA
CTD PMID:30029170 PMID:33051911 PMID:33396045 NCBI chr12:31,296,143...31,362,649
Ensembl chr12:31,296,156...31,362,647
JBrowse link
G Scn10a sodium voltage-gated channel alpha subunit 10 multiple interactions
affects activity
EXP cyhalothrin affects the reaction [SCN10A protein results in increased transport of Sodium]
cyhalothrin affects the activity of SCN10A protein
CTD PMID:16051293 PMID:19766671 NCBI chr 8:119,350,723...119,462,882
Ensembl chr 8:119,350,724...119,462,614
JBrowse link
G Sirt1 sirtuin 1 multiple interactions EXP [Allethrins co-treated with cyhalothrin co-treated with cypermethrin co-treated with decamethrin co-treated with fenvalerate] results in decreased expression of SIRT1 mRNA; [cypermethrin co-treated with decamethrin co-treated with fenvalerate co-treated with cyhalothrin co-treated with Allethrins] results in increased expression of SIRT1 mRNA CTD PMID:33051911 PMID:33396045 NCBI chr20:25,307,143...25,329,260
Ensembl chr20:25,306,917...25,329,260
JBrowse link
G Slc18a2 solute carrier family 18 member A2 decreases expression EXP cyhalothrin results in decreased expression of SLC18A2 protein CTD PMID:28495607 NCBI chr 1:258,413,748...258,449,143
Ensembl chr 1:258,413,959...258,448,325
JBrowse link
G Slc6a3 solute carrier family 6 member 3 decreases expression EXP cyhalothrin results in decreased expression of SLC6A3 protein CTD PMID:28495607 NCBI chr 1:29,709,443...29,750,413
Ensembl chr 1:29,709,443...29,750,413
JBrowse link
G Sod2 superoxide dismutase 2 increases activity EXP cyhalothrin results in increased activity of SOD2 protein CTD PMID:29727961 NCBI chr 1:47,638,318...47,645,163
Ensembl chr 1:47,636,528...47,645,189
JBrowse link
G Sox9 SRY-box transcription factor 9 multiple interactions EXP [Allethrins co-treated with cyhalothrin co-treated with cypermethrin co-treated with decamethrin co-treated with fenvalerate] results in increased expression of SOX9 mRNA; [cypermethrin co-treated with decamethrin co-treated with fenvalerate co-treated with cyhalothrin co-treated with Allethrins] affects the expression of SOX9 mRNA CTD PMID:33051911 PMID:33396045 NCBI chr10:97,806,485...97,811,994
Ensembl chr10:97,806,485...97,811,994
JBrowse link
G Src SRC proto-oncogene, non-receptor tyrosine kinase affects binding ISO cyhalothrin binds to SRC protein CTD PMID:32278787 NCBI chr 3:146,091,969...146,139,492
Ensembl chr 3:146,091,841...146,139,476
JBrowse link
G Srebf1 sterol regulatory element binding transcription factor 1 increases expression EXP cyhalothrin results in increased expression of SREBF1 mRNA CTD PMID:27348886 NCBI chr10:45,007,637...45,029,650
Ensembl chr10:45,007,637...45,029,650
JBrowse link
G Star steroidogenic acute regulatory protein multiple interactions
decreases expression
EXP [Allethrins co-treated with cyhalothrin co-treated with cypermethrin co-treated with decamethrin co-treated with fenvalerate] affects the expression of STAR mRNA; [cypermethrin co-treated with decamethrin co-treated with fenvalerate co-treated with cyhalothrin co-treated with Allethrins] results in increased expression of STAR mRNA; Taurine inhibits the reaction [cyhalothrin results in decreased expression of STAR mRNA]; Taurine inhibits the reaction [cyhalothrin results in decreased expression of STAR protein]
cyhalothrin results in decreased expression of STAR mRNA; cyhalothrin results in decreased expression of STAR protein
CTD PMID:29506456 PMID:30029170 PMID:33051911 PMID:33396045 NCBI chr16:66,267,094...66,274,368
Ensembl chr16:66,264,807...66,271,672
JBrowse link
G Syngap1 synaptic Ras GTPase activating protein 1 increases expression EXP cyhalothrin results in increased expression of SYNGAP1 protein CTD PMID:28487251 NCBI chr20:5,026,366...5,056,659
Ensembl chr20:5,026,364...5,056,672
JBrowse link
G Tet1 tet methylcytosine dioxygenase 1 multiple interactions EXP [Allethrins co-treated with cyhalothrin co-treated with cypermethrin co-treated with decamethrin co-treated with fenvalerate] results in decreased expression of TET1 mRNA; [cypermethrin co-treated with decamethrin co-treated with fenvalerate co-treated with cyhalothrin co-treated with Allethrins] results in increased expression of TET1 mRNA CTD PMID:33051911 PMID:33396045 NCBI chr20:25,761,042...25,840,926
Ensembl chr20:25,768,120...25,833,052
JBrowse link
G Tff1 trefoil factor 1 increases expression ISO cyhalothrin results in increased expression of TFF1 mRNA CTD PMID:18419197 PMID:20097460 NCBI chr20:9,235,736...9,239,597
Ensembl chr20:9,235,736...9,239,597
JBrowse link
G Tgfb1 transforming growth factor, beta 1 multiple interactions EXP [Allethrins co-treated with cyhalothrin co-treated with cypermethrin co-treated with decamethrin co-treated with fenvalerate] results in decreased expression of TGFB1 mRNA; [cypermethrin co-treated with decamethrin co-treated with fenvalerate co-treated with cyhalothrin co-treated with Allethrins] results in increased expression of TGFB1 mRNA CTD PMID:33051911 PMID:33396045 NCBI chr 1:81,196,532...81,212,848
Ensembl chr 1:81,196,532...81,212,847
JBrowse link
G Th tyrosine hydroxylase decreases expression EXP cyhalothrin results in decreased expression of TH protein CTD PMID:22366556 PMID:28495607 NCBI chr 1:198,071,500...198,078,832
Ensembl chr 1:198,071,503...198,109,767
JBrowse link
G Thrb thyroid hormone receptor beta multiple interactions ISO cyhalothrin inhibits the reaction [Triiodothyronine results in increased activity of THRB protein] CTD PMID:28531659 NCBI chr15:7,685,180...8,031,920
Ensembl chr15:7,685,180...7,882,916
JBrowse link
G Thy1 Thy-1 cell surface antigen multiple interactions EXP [Allethrins co-treated with cyhalothrin co-treated with cypermethrin co-treated with decamethrin co-treated with fenvalerate] results in decreased expression of THY1 mRNA; [cypermethrin co-treated with decamethrin co-treated with fenvalerate co-treated with cyhalothrin co-treated with Allethrins] results in decreased expression of THY1 mRNA CTD PMID:33051911 PMID:33396045 NCBI chr 8:44,389,495...44,394,688
Ensembl chr 8:44,389,513...44,394,659
JBrowse link
G Tnf tumor necrosis factor multiple interactions
increases expression
EXP thymoquinone inhibits the reaction [cyhalothrin results in increased expression of TNF mRNA]; thymoquinone inhibits the reaction [cyhalothrin results in increased expression of TNF protein]
cyhalothrin results in increased expression of TNF mRNA; cyhalothrin results in increased expression of TNF protein
CTD PMID:26645134 PMID:27348886 PMID:28058584 NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629
JBrowse link
G Tnp1 transition protein 1 multiple interactions EXP [Allethrins co-treated with cyhalothrin co-treated with cypermethrin co-treated with decamethrin co-treated with fenvalerate] results in decreased expression of TNP1 mRNA; [cypermethrin co-treated with decamethrin co-treated with fenvalerate co-treated with cyhalothrin co-treated with Allethrins] results in decreased expression of TNP1 mRNA CTD PMID:33051911 PMID:33396045 NCBI chr 9:74,594,463...74,595,072
Ensembl chr 9:74,594,466...74,595,274
JBrowse link
G Tnp2 transition protein 2 multiple interactions EXP [Allethrins co-treated with cyhalothrin co-treated with cypermethrin co-treated with decamethrin co-treated with fenvalerate] affects the expression of TNP2 mRNA; [cypermethrin co-treated with decamethrin co-treated with fenvalerate co-treated with cyhalothrin co-treated with Allethrins] results in decreased expression of TNP2 mRNA CTD PMID:33051911 PMID:33396045 NCBI chr10:4,879,812...4,880,540
Ensembl chr10:4,879,812...4,880,538
JBrowse link
G Tp53 tumor protein p53 increases expression ISO cyhalothrin results in increased expression of TRP53 mRNA CTD PMID:20097460 NCBI chr10:54,300,070...54,311,525
Ensembl chr10:54,300,048...54,311,524
JBrowse link
G Trdmt1 tRNA aspartic acid methyltransferase 1 multiple interactions EXP [Allethrins co-treated with cyhalothrin co-treated with cypermethrin co-treated with decamethrin co-treated with fenvalerate] affects the expression of DNMT2 mRNA; [cypermethrin co-treated with decamethrin co-treated with fenvalerate co-treated with cyhalothrin co-treated with Allethrins] results in decreased expression of TRDMT1 mRNA CTD PMID:33051911 PMID:33396045 NCBI chr17:76,601,966...76,646,104
Ensembl chr17:76,610,543...76,645,439
JBrowse link
G Trpm2 transient receptor potential cation channel, subfamily M, member 2 multiple interactions EXP [cypermethrin co-treated with decamethrin co-treated with fenvalerate co-treated with cyhalothrin co-treated with Allethrins] results in increased expression of TRPM2 mRNA CTD PMID:33396045 NCBI chr20:10,703,568...10,753,189
Ensembl chr20:10,707,014...10,753,181
JBrowse link
G Tsc22d3 TSC22 domain family, member 3 multiple interactions ISO cyhalothrin inhibits the reaction [Hydrocortisone results in increased expression of TSC22D3 mRNA] CTD PMID:26647222 NCBI chr  X:104,217,898...104,277,935
Ensembl chr  X:104,217,925...104,276,861
JBrowse link
G Tspo translocator protein multiple interactions EXP [Allethrins co-treated with cyhalothrin co-treated with cypermethrin co-treated with decamethrin co-treated with fenvalerate] affects the expression of TSPO mRNA; [cypermethrin co-treated with decamethrin co-treated with fenvalerate co-treated with cyhalothrin co-treated with Allethrins] results in increased expression of TSPO mRNA CTD PMID:33051911 PMID:33396045 NCBI chr 7:114,720,188...114,730,450
Ensembl chr 7:114,720,188...114,730,450
JBrowse link
G Tubb3 tubulin, beta 3 class III multiple interactions EXP cyhalothrin promotes the reaction [NGF protein results in increased expression of TUBB3 mRNA] CTD PMID:28385489 NCBI chr19:51,457,187...51,466,243
Ensembl chr19:51,457,184...51,466,243
JBrowse link
G Vim vimentin multiple interactions EXP [Allethrins co-treated with cyhalothrin co-treated with cypermethrin co-treated with decamethrin co-treated with fenvalerate] affects the expression of VIM mRNA; [cypermethrin co-treated with decamethrin co-treated with fenvalerate co-treated with cyhalothrin co-treated with Allethrins] results in increased expression of VIM mRNA CTD PMID:33051911 PMID:33396045 NCBI chr17:76,668,701...76,677,186
Ensembl chr17:76,668,647...76,677,187
JBrowse link
G Wnt1 Wnt family member 1 multiple interactions EXP [cypermethrin co-treated with decamethrin co-treated with fenvalerate co-treated with cyhalothrin co-treated with Allethrins] results in decreased expression of WNT1 mRNA CTD PMID:33396045 NCBI chr 7:129,938,604...129,942,651
Ensembl chr 7:129,938,604...129,942,651
JBrowse link
G Wnt4 Wnt family member 4 multiple interactions EXP [Allethrins co-treated with cyhalothrin co-treated with cypermethrin co-treated with decamethrin co-treated with fenvalerate] results in increased expression of WNT4 mRNA; [cypermethrin co-treated with decamethrin co-treated with fenvalerate co-treated with cyhalothrin co-treated with Allethrins] results in increased expression of WNT4 mRNA CTD PMID:33051911 PMID:33396045 NCBI chr 5:149,513,573...149,535,415
Ensembl chr 5:149,514,018...149,532,859
JBrowse link
G Xdh xanthine dehydrogenase decreases expression EXP cyhalothrin results in decreased expression of XDH mRNA CTD PMID:29727961 NCBI chr 6:21,530,463...21,592,172
Ensembl chr 6:21,530,113...21,592,268
JBrowse link
G Ybx2 Y box binding protein 2 multiple interactions EXP [Allethrins co-treated with cyhalothrin co-treated with cypermethrin co-treated with decamethrin co-treated with fenvalerate] results in decreased expression of YBX2 mRNA; [cypermethrin co-treated with decamethrin co-treated with fenvalerate co-treated with cyhalothrin co-treated with Allethrins] affects the expression of YBX2 mRNA CTD PMID:33051911 PMID:33396045 NCBI chr10:54,659,719...54,665,371
Ensembl chr10:54,659,719...54,665,371
JBrowse link
G Zbtb16 zinc finger and BTB domain containing 16 multiple interactions EXP [Allethrins co-treated with cyhalothrin co-treated with cypermethrin co-treated with decamethrin co-treated with fenvalerate] affects the expression of ZBTB16 mRNA; [cypermethrin co-treated with decamethrin co-treated with fenvalerate co-treated with cyhalothrin co-treated with Allethrins] results in increased expression of ZBTB16 mRNA CTD PMID:33051911 PMID:33396045 NCBI chr 8:48,989,376...49,177,011
Ensembl chr 8:48,994,566...49,177,011
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19812
    role 19761
      application 19471
        agrochemical 15039
          cyhalothrin 160
            gamma-cyhalothrin + 0
            lambda-cyhalothrin 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 19812
    subatomic particle 19811
      composite particle 19811
        hadron 19811
          baryon 19811
            nucleon 19811
              atomic nucleus 19811
                atom 19811
                  main group element atom 19708
                    p-block element atom 19708
                      carbon group element atom 19630
                        carbon atom 19620
                          organic molecular entity 19620
                            organic group 18728
                              organic divalent group 18719
                                organodiyl group 18719
                                  carbonyl group 18667
                                    carbonyl compound 18667
                                      carboxylic acid 18364
                                        monocarboxylic acid 17632
                                          cyclopropanecarboxylic acid 1676
                                            3-(2-chloro-3,3,3-trifluoroprop-1-en-1-yl)-2,2-dimethylcyclopropanecarboxylic acid 160
                                              cyhalothrin 160
                                                gamma-cyhalothrin + 0
                                                lambda-cyhalothrin 0
paths to the root