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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:allopurinol
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Accession:CHEBI:40279 term browser browse the term
Definition:A bicyclic structure comprising a pyrazole ring fused to a hydroxy-substituted pyrimidine ring.
Synonyms:related_synonym: 1,5-Dihydro-4H-pyrazolo(3,4-d)pyrimidin-4-one;   1,5-Dihydro-4H-pyrazolo(3,4-d)pyrimidine-4-one;   1H-Pyrazolo(3,4-d)pyrimidin-4-ol;   4'-Hydroxypyrazolol(3,4-d)pyrimidine;   4-HPP;   4-Hydroxy-1H-pyrazolo(3,4-d)pyrimidine;   4-Hydroxy-3,4-pyrazolopyrimidine;   4-Hydroxypyrazolo(3,4-d)pyrimidine;   4-Hydroxypyrazolopyrimidine;   4-Hydroxypyrazolyl(3,4-d)pyrimidine;   4H-Pyrazolo(3,4-d)pyrimidin-4-one;   AL-100;   Allopurinolum;   Alopurinol;   Formula=C5H4N4O;   InChI=1S/C5H4N4O/c10-5-3-1-8-9-4(3)6-2-7-5/h1-2H,(H2,6,7,8,9,10);   InChIKey=OFCNXPDARWKPPY-UHFFFAOYSA-N;   SMILES=Oc1ncnc2[nH]ncc12;   Zyloprim (TN)
 alt_id: CHEBI:2601;   CHEBI:40276
 xref: Beilstein:608611;   CAS:315-30-0;   DrugBank:DB00437;   Drug_Central:124;   KEGG:D00224;   LINCS:LSM-5919
 xref_mesh: MESH:D000493
 xref: PMID:11333159;   PMID:16650385;   PMID:24395556;   PMID:24590210;   PMID:24591375;   PMID:7602118;   Reaxys:608611;   Wikipedia:Allopurinol



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allopurinol term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G PLN phospholamban affects expression EXP Allopurinol affects the expression of PLN mRNA; Allopurinol affects the expression of PLN protein; Allopurinol affects the expression of PLN protein modified form CTD PMID:17071724 NCBI chr 1:58,579,095...58,590,541
Ensembl chr 1:58,579,145...58,590,535
JBrowse link
G SLC8A1 solute carrier family 8 member A1 affects expression EXP Allopurinol affects the expression of SLC8A1 mRNA; Allopurinol affects the expression of SLC8A1 protein CTD PMID:17071724 NCBI chr17:32,004,207...32,381,399
Ensembl chr17:32,005,245...32,307,700
JBrowse link

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  CHEBI ontology 397
    role 397
      biological role 397
        biochemical role 356
          antimetabolite 3
            allopurinol 2
              allopurinol riboside 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 397
    subatomic particle 397
      composite particle 397
        hadron 397
          baryon 397
            nucleon 397
              atomic nucleus 397
                atom 397
                  main group element atom 390
                    p-block element atom 390
                      carbon group element atom 379
                        carbon atom 378
                          organic molecular entity 378
                            organic molecule 368
                              organic cyclic compound 351
                                organic heterocyclic compound 314
                                  organic heteropolycyclic compound 86
                                    organic heterobicyclic compound 43
                                      mancude organic heterobicyclic parent 5
                                        1H-pyrazolo[4,3-d]pyrimidine 2
                                          allopurinol 2
                                            allopurinol riboside 0
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