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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:cyclopentolate
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Accession:CHEBI:4024 term browser browse the term
Definition:A carboxylic ester resulting from the formal condensation of (1-hydroxycyclopentyl)(phenyl)acetic acid with N,N-dimethylethanolamine. A tertiary amine antimuscarinic with actions similar to atropine, it is used as its hydrochloride salt to produce mydriasis (excessive dilation of the pupil) and cycloplegia (paralysis of the ciliary muscle of the eye) for opthalmic diagnostic procedures. It acts more quickly than atropine and has a shorter duration of action.
Synonyms:exact_synonym: 2-(dimethylamino)ethyl (1-hydroxycyclopentyl)(phenyl)acetate
 related_synonym: 1-hydroxy-alpha-phenylcyclopentaneacetic acid 2-(dimethylamino)ethyl ester;   2-(dimethylamino)ethyl 1-hydroxy-alpha-phenylcyclopentaneacetate;   2-(dimethylamino)ethyl 2-(1-hydroxycyclopentyl)-2-phenylacetate;   2-phenyl-2-(1-hydroxycyclopentyl)ethanoic acid beta-(dimethylamino)ethyl ester;   Formula=C17H25NO3;   InChI=1S/C17H25NO3/c1-18(2)12-13-21-16(19)15(14-8-4-3-5-9-14)17(20)10-6-7-11-17/h3-5,8-9,15,20H,6-7,10-13H2,1-2H3;   InChIKey=SKYSRIRYMSLOIN-UHFFFAOYSA-N;   SMILES=CN(C)CCOC(=O)C(c1ccccc1)C1(O)CCCC1;   alpha-(1-hydroxycyclopentyl)benzeneacetic acid 2-(dimethylamino)ethyl ester;   beta-(dimethylamino)ethyl (1-hydroxycyclopentyl)phenylacetate;   beta-dimethylaminoethyl (1-hydroxycyclopentyl)phenylacetate;   ciclopentolato;   cyclopentolatum
 xref: Beilstein:2147087;   CAS:512-15-2;   DrugBank:DB00979;   Drug_Central:757;   HMDB:HMDB0015114;   KEGG:C06932;   KEGG:D07759;   LINCS:LSM-1800;   Patent:US2554511;   Reaxys:2147087;   Wikipedia:Cyclopentolate


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Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19831
    role 19807
      application 19650
        curing agent 1
          N,N-dimethylethanolamine 1
            cyclopentolate 0
              (R)-cyclopentolate + 0
              (S)-cyclopentolate + 0
              cyclopentolate hydrochloride + 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 19831
    subatomic particle 19829
      composite particle 19829
        hadron 19829
          baryon 19829
            nucleon 19829
              atomic nucleus 19829
                atom 19829
                  main group element atom 19779
                    main group molecular entity 19779
                      s-block molecular entity 19617
                        hydrogen molecular entity 19604
                          hydrides 19102
                            inorganic hydride 18114
                              pnictogen hydride 18103
                                nitrogen hydride 18010
                                  azane 17819
                                    ammonia 17818
                                      organic amino compound 17818
                                        amino alcohol 1071
                                          ethanolamines 821
                                            N,N-dimethylethanolamine 1
                                              cyclopentolate 0
                                                (R)-cyclopentolate + 0
                                                (S)-cyclopentolate + 0
                                                cyclopentolate hydrochloride + 0
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