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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:5-fluorouridine
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Accession:CHEBI:40154 term browser browse the term
Definition:An organofluorine compound that is uridine bearing a fluoro substituent at position 5 on the uracil ring.
Synonyms:related_synonym: 5-Fluoro-uridine;   5-Fluorouracil 1beta-D-ribofuranoside;   Formula=C9H11FN2O6;   InChI=1S/C9H11FN2O6/c10-3-1-12(9(17)11-7(3)16)8-6(15)5(14)4(2-13)18-8/h1,4-6,8,13-15H,2H2,(H,11,16,17)/t4-,5-,6-,8-/m1/s1;   InChIKey=FHIDNBAQOFJWCA-UAKXSSHOSA-N;   SMILES=OC[C@H]1O[C@H]([C@H](O)[C@@H]1O)n1cc(F)c(=O)[nH]c1=O
 alt_id: CHEBI:46390;   CHEBI:73164
 xref: Beilstein:33662;   CAS:316-46-1;   DrugBank:DB01629;   Gmelin:466575;   KEGG:C16633
 xref_mesh: MESH:C001943
 xref: MetaCyc:CPD0-2367;   PDBeChem:5UD;   PMID:12039627;   PMID:21744792;   Patent:EP1600153;   Patent:EP927045;   Patent:US2005208122;   Patent:US5734042;   Patent:US6372725;   Reaxys:33662



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5-fluorouridine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcc5 ATP binding cassette subfamily C member 5 increases export ISO ABCC5 protein results in increased export of 5-fluorouridine CTD PMID:15897250 NCBI chr11:80,473,809...80,567,257
Ensembl chr11:80,473,872...80,567,253
JBrowse link
G Sod1 superoxide dismutase 1 affects binding ISO 5-fluorouridine binds to SOD1 protein; 5-fluorouridine binds to SOD1 protein mutant form CTD PMID:23612299 NCBI chr11:29,456,673...29,462,249
Ensembl chr11:29,456,558...29,462,249
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Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 20059
    role 20009
      biological role 20008
        aetiopathogenetic role 19264
          genotoxin 17562
            mutagen 17462
              5-fluorouridine 2
Path 2
Term Annotations click to browse term
  CHEBI ontology 20059
    subatomic particle 20056
      composite particle 20056
        hadron 20056
          baryon 20056
            nucleon 20056
              atomic nucleus 20056
                atom 20056
                  main group element atom 19956
                    p-block element atom 19956
                      carbon group element atom 19882
                        carbon atom 19873
                          organic molecular entity 19873
                            heteroorganic entity 19555
                              organochalcogen compound 19293
                                organooxygen compound 19239
                                  carbohydrates and carbohydrate derivatives 13914
                                    carbohydrate 13914
                                      carbohydrate derivative 13640
                                        glycosyl compound 12896
                                          N-glycosyl compound 5529
                                            nucleoside 5390
                                              ribonucleoside 690
                                                pyrimidine ribonucleosides 152
                                                  uridines 49
                                                    5-fluorouridine 2
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