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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:5-fluorouridine
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Accession:CHEBI:40154 term browser browse the term
Definition:An organofluorine compound that is uridine bearing a fluoro substituent at position 5 on the uracil ring.
Synonyms:related_synonym: 5-Fluoro-uridine;   5-Fluorouracil 1beta-D-ribofuranoside;   Formula=C9H11FN2O6;   InChI=1S/C9H11FN2O6/c10-3-1-12(9(17)11-7(3)16)8-6(15)5(14)4(2-13)18-8/h1,4-6,8,13-15H,2H2,(H,11,16,17)/t4-,5-,6-,8-/m1/s1;   InChIKey=FHIDNBAQOFJWCA-UAKXSSHOSA-N;   SMILES=OC[C@H]1O[C@H]([C@H](O)[C@@H]1O)n1cc(F)c(=O)[nH]c1=O
 alt_id: CHEBI:46390;   CHEBI:73164
 xref: Beilstein:33662;   CAS:316-46-1;   DrugBank:DB01629;   Gmelin:466575;   KEGG:C16633
 xref_mesh: MESH:C001943
 xref: MetaCyc:CPD0-2367;   PDBeChem:5UD;   PMID:12039627;   PMID:21744792;   Patent:EP1600153;   Patent:EP927045;   Patent:US2005208122;   Patent:US5734042;   Patent:US6372725;   Reaxys:33662


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5-fluorouridine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcc5 ATP binding cassette subfamily C member 5 increases export ISO ABCC5 protein results in increased export of 5-fluorouridine CTD PMID:15897250 NCBI chr11:84,395,982...84,490,215
Ensembl chr11:84,396,033...84,490,211
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G Sod1 superoxide dismutase 1 affects binding ISO 5-fluorouridine binds to SOD1 protein; 5-fluorouridine binds to SOD1 protein mutant form CTD PMID:23612299 NCBI chr11:30,363,282...30,368,858
Ensembl chr11:30,363,280...30,368,862
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Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19761
    role 19711
      biological role 19711
        aetiopathogenetic role 18963
          genotoxin 17330
            mutagen 17208
              5-fluorouridine 2
Path 2
Term Annotations click to browse term
  CHEBI ontology 19761
    subatomic particle 19759
      composite particle 19759
        hadron 19759
          baryon 19759
            nucleon 19759
              atomic nucleus 19759
                atom 19759
                  main group element atom 19653
                    p-block element atom 19653
                      carbon group element atom 19569
                        carbon atom 19559
                          organic molecular entity 19559
                            heteroorganic entity 19195
                              organochalcogen compound 18941
                                organooxygen compound 18868
                                  carbohydrates and carbohydrate derivatives 12260
                                    carbohydrate 12260
                                      carbohydrate derivative 11888
                                        glycosyl compound 10962
                                          N-glycosyl compound 5484
                                            nucleoside 5345
                                              ribonucleoside 667
                                                pyrimidine ribonucleosides 148
                                                  uridines 48
                                                    5-fluorouridine 2
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