The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
desflurane inhibits the reaction [TNF protein results in increased expression of ICAM1 mRNA]; desflurane inhibits the reaction [TNF protein results in increased expression of ICAM1 protein]
desflurane inhibits the reaction [TNF protein results in increased expression of ICAM1 mRNA]; desflurane inhibits the reaction [TNF protein results in increased expression of ICAM1 protein]; desflurane inhibits the reaction [TNF protein results in increased expression of SELE protein]; desflurane inhibits the reaction [TNF protein results in increased expression of VCAM1 mRNA]
Enflurane inhibits the reaction [Trichloroethylene promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB1 protein]]]
Enflurane inhibits the reaction [Trichloroethylene promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB1 protein]]]; Enflurane promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA2 protein binds to GABRB1 protein]]
calpain inhibitor III inhibits the reaction [Isoflurane results in increased cleavage of and affects the localization of AIFM1 protein]; Isoflurane results in increased cleavage of and affects the localization of AIFM1 protein; pyrazolanthrone inhibits the reaction [Isoflurane results in increased cleavage of and affects the localization of AIFM1 protein]
Isoflurane results in increased phosphorylation of AKT1 protein 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [IGF1 protein inhibits the reaction [Isoflurane results in decreased phosphorylation of AKT1 protein]]; IGF1 protein inhibits the reaction [Isoflurane results in decreased phosphorylation of AKT1 protein]; MK 2206 inhibits the reaction [IGF1 protein inhibits the reaction [Isoflurane results in decreased phosphorylation of AKT1 protein]]; Sirolimus inhibits the reaction [IGF1 protein inhibits the reaction [Isoflurane results in decreased phosphorylation of AKT1 protein]]; U 0126 inhibits the reaction [IGF1 protein inhibits the reaction [Isoflurane results in decreased phosphorylation of AKT1 protein]] fraxetin inhibits the reaction [Isoflurane results in decreased phosphorylation of AKT1 protein]
APP protein promotes the reaction [Isoflurane results in increased cleavage of and results in increased activity of CASP3 protein]; benzyloxycarbonyl-valyl-alanyl-aspartic acid inhibits the reaction [Isoflurane affects the expression of APP protein alternative form]; Isoflurane affects the metabolism of and affects the expression of and affects the secretion of APP protein alternative form
Isoflurane results in decreased expression of BAX mRNA Isoflurane results in increased expression of BAX protein pyrazolanthrone inhibits the reaction [Isoflurane results in increased expression of BAX protein]
[Antagomirs results in decreased expression of MIR140 mRNA] inhibits the reaction [Isoflurane results in decreased expression of BCL2 protein]; Dexmedetomidine inhibits the reaction [Isoflurane results in decreased expression of BCL2 protein]; Isoflurane inhibits the reaction [Hydrogen Peroxide results in decreased expression of BCL2 protein]; Isoflurane promotes the reaction [Oxygen deficiency results in increased expression of BCL2 protein] Isoflurane affects the expression of BCL2 protein
Isoflurane results in increased expression of CAPN1 protein calpain inhibitor III inhibits the reaction [Isoflurane results in increased expression of CAPN1 protein]; pyrazolanthrone inhibits the reaction [Isoflurane results in increased expression of CAPN1 protein]
Isoflurane results in increased expression of CAPN2 protein calpain inhibitor III inhibits the reaction [Isoflurane results in increased expression of CAPN2 protein]; CAPN2 protein affects the reaction [Isoflurane results in decreased expression of EPB41L1 protein]; CAPN2 protein affects the reaction [Isoflurane results in decreased expression of SLC12A5 protein]; ifenprodil inhibits the reaction [Isoflurane results in increased expression of CAPN2 protein]; pyrazolanthrone inhibits the reaction [Isoflurane results in increased expression of CAPN2 protein]
Isoflurane results in increased cleavage of CASP1 protein N-(1,2,3,5,6,7-hexahydro-S-indacen-4-ylcarbamoyl)-4-(2-hydroxy-2-propanyl)-2-furansulfonamide inhibits the reaction [Isoflurane results in increased cleavage of CASP1 protein]; SETD7 protein affects the reaction [Isoflurane results in increased cleavage of CASP1 protein]
APP protein promotes the reaction [Isoflurane results in increased cleavage of and results in increased activity of CASP3 protein]; Clioquinol inhibits the reaction [Isoflurane results in increased cleavage of and results in increased activity of CASP3 protein]; Isoflurane results in increased cleavage of and results in increased activity of CASP3 protein Isoflurane results in increased cleavage of CASP3 protein [Antagomirs results in decreased expression of MIR140 mRNA] inhibits the reaction [Isoflurane results in increased expression of CASP3 protein modified form]; Dexmedetomidine inhibits the reaction [Isoflurane results in increased expression of CASP3 protein]; IGF1 protein inhibits the reaction [Isoflurane results in increased cleavage of CASP3 protein]; Isoflurane inhibits the reaction [Hydrogen Peroxide results in increased activity of CASP3 protein]; PF-4708671 promotes the reaction [Isoflurane results in increased cleavage of CASP3 protein]; pyrazolanthrone inhibits the reaction [Isoflurane results in increased expression of CASP3 protein modified form] Isoflurane results in increased expression of CASP3 protein; Isoflurane results in increased expression of CASP3 protein modified form Isoflurane results in decreased expression of CASP3 mRNA Isoflurane results in increased activity of CASP3 protein resveratrol inhibits the reaction [Isoflurane results in increased activity of CASP3 protein]
Isoflurane inhibits the reaction [Hydrogen Peroxide results in increased activity of CASP7 protein] Isoflurane results in increased expression of CASP7 mRNA
NFE2L2 protein affects the reaction [trilobatin inhibits the reaction [Isoflurane results in decreased activity of CAT protein]]; Resveratrol inhibits the reaction [Isoflurane results in decreased activity of CAT protein]; trilobatin inhibits the reaction [Isoflurane results in decreased activity of CAT protein]
Isoflurane results in decreased expression of DLG4 protein IGF1 protein inhibits the reaction [Isoflurane results in decreased expression of DLG4 protein]; PF-4708671 promotes the reaction [Isoflurane results in decreased expression of DLG4 protein]
Isoflurane results in decreased expression of EPB41L1 protein CAPN2 protein affects the reaction [Isoflurane results in decreased expression of EPB41L1 protein]; ifenprodil inhibits the reaction [Isoflurane results in decreased expression of EPB41L1 protein]
Isoflurane results in increased cleavage of GSDMD protein SETD7 protein affects the reaction [Isoflurane results in increased cleavage of GSDMD protein]
Isoflurane results in increased activity of HMOX1 protein Isoflurane results in increased expression of HMOX1 mRNA; Isoflurane results in increased expression of HMOX1 protein trilobatin promotes the reaction [Isoflurane results in increased expression of HMOX1 mRNA]; trilobatin promotes the reaction [Isoflurane results in increased expression of HMOX1 protein] Isoflurane results in decreased expression of HMOX1 mRNA 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Dexmedetomidine inhibits the reaction [Isoflurane results in decreased expression of and results in decreased activity of HMOX1 protein]]; 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Dexmedetomidine inhibits the reaction [Isoflurane results in decreased expression of HMOX1 mRNA]]; 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Dexmedetomidine inhibits the reaction [Isoflurane results in decreased expression of HMOX1 protein]]; Dexmedetomidine inhibits the reaction [Isoflurane results in decreased expression of and results in decreased activity of HMOX1 protein]; Dexmedetomidine inhibits the reaction [Isoflurane results in decreased expression of HMOX1 mRNA]; Isoflurane results in decreased expression of and results in decreased activity of HMOX1 protein
Isoflurane promotes the reaction [HTT protein mutant form binds to HTT protein mutant form]; xestospongin C inhibits the reaction [Isoflurane promotes the reaction [HTT protein mutant form binds to HTT protein mutant form]]
Isoflurane results in decreased expression of ICAM1 mRNA Isoflurane results in decreased expression of ICAM1 mRNA; Isoflurane results in decreased expression of ICAM1 protein Isoflurane inhibits the reaction [ITGAL protein binds to ICAM1 protein]; Isoflurane inhibits the reaction [ITGAM protein binds to ICAM1 protein]
2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [IGF1 protein inhibits the reaction [Isoflurane results in decreased phosphorylation of AKT1 protein]]; [IGF1 protein co-treated with U 0126] promotes the reaction [Isoflurane results in decreased phosphorylation of MAPK1 protein]; IGF1 protein inhibits the reaction [Isoflurane results in decreased expression of DLG4 protein]; IGF1 protein inhibits the reaction [Isoflurane results in decreased phosphorylation of AKT1 protein]; IGF1 protein inhibits the reaction [Isoflurane results in decreased phosphorylation of RPS6 protein]; IGF1 protein inhibits the reaction [Isoflurane results in increased cleavage of CASP3 protein]; MK 2206 inhibits the reaction [IGF1 protein inhibits the reaction [Isoflurane results in decreased phosphorylation of AKT1 protein]]; Sirolimus inhibits the reaction [[IGF1 protein co-treated with U 0126] promotes the reaction [Isoflurane results in decreased phosphorylation of MAPK1 protein]]; Sirolimus inhibits the reaction [IGF1 protein inhibits the reaction [Isoflurane results in decreased phosphorylation of AKT1 protein]]; U 0126 inhibits the reaction [IGF1 protein inhibits the reaction [Isoflurane results in decreased phosphorylation of AKT1 protein]] Isoflurane results in decreased expression of IGF1 protein
N-(1,2,3,5,6,7-hexahydro-S-indacen-4-ylcarbamoyl)-4-(2-hydroxy-2-propanyl)-2-furansulfonamide inhibits the reaction [Isoflurane results in increased expression of IL18 protein]; SETD7 protein affects the reaction [Isoflurane results in increased expression of IL18 protein]
Isoflurane results in decreased expression of IL1B mRNA Isoflurane results in increased expression of IL1B mRNA; Isoflurane results in increased expression of IL1B protein MEG3 mRNA affects the reaction [Isoflurane results in increased expression of IL1B protein]; MIR7-1 mRNA affects the reaction [MEG3 mRNA affects the reaction [Isoflurane results in increased expression of IL1B protein]]; rhodioloside inhibits the reaction [Isoflurane results in increased expression of IL1B protein] MEG3 mRNA affects the reaction [Isoflurane results in increased expression of IL1B protein]; N-(1,2,3,5,6,7-hexahydro-S-indacen-4-ylcarbamoyl)-4-(2-hydroxy-2-propanyl)-2-furansulfonamide inhibits the reaction [Isoflurane results in increased expression of IL1B protein]; SETD7 protein affects the reaction [Isoflurane results in increased expression of IL1B protein]
Isoflurane results in decreased expression of IL6 protein MEG3 mRNA affects the reaction [Isoflurane results in increased expression of IL6 protein]; SETD7 protein affects the reaction [Isoflurane results in increased expression of IL6 protein] MEG3 mRNA affects the reaction [Isoflurane results in increased expression of IL6 protein]; MIR7-1 mRNA affects the reaction [MEG3 mRNA affects the reaction [Isoflurane results in increased expression of IL6 protein]]
Isoflurane results in decreased phosphorylation of MAPK1 protein 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Dexmedetomidine inhibits the reaction [Isoflurane results in decreased phosphorylation of MAPK1 protein]]; 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one promotes the reaction [Dexmedetomidine inhibits the reaction [Isoflurane results in decreased phosphorylation of MAPK1 protein]]; [IGF1 protein co-treated with U 0126] promotes the reaction [Isoflurane results in decreased phosphorylation of MAPK1 protein]; Dexmedetomidine inhibits the reaction [Isoflurane results in decreased phosphorylation of MAPK1 protein]; Sirolimus inhibits the reaction [[IGF1 protein co-treated with U 0126] promotes the reaction [Isoflurane results in decreased phosphorylation of MAPK1 protein]]
Isoflurane results in increased expression of MEG3 mRNA MEG3 mRNA affects the reaction [Isoflurane results in decreased expression of MIR7-1 mRNA]; MEG3 mRNA affects the reaction [Isoflurane results in increased expression of IL1B protein]; MEG3 mRNA affects the reaction [Isoflurane results in increased expression of IL6 protein]; MEG3 mRNA affects the reaction [Isoflurane results in increased expression of TNF protein]; MIR7-1 mRNA affects the reaction [MEG3 mRNA affects the reaction [Isoflurane results in increased expression of IL1B protein]]; MIR7-1 mRNA affects the reaction [MEG3 mRNA affects the reaction [Isoflurane results in increased expression of IL6 protein]]; MIR7-1 mRNA affects the reaction [MEG3 mRNA affects the reaction [Isoflurane results in increased expression of TNF protein]]
Isoflurane results in increased expression of MIR140 mRNA [Antagomirs results in decreased expression of MIR140 mRNA] inhibits the reaction [Isoflurane results in decreased expression of BCL2 protein]; [Antagomirs results in decreased expression of MIR140 mRNA] inhibits the reaction [Isoflurane results in increased expression of CASP3 protein modified form]; [Antagomirs results in decreased expression of MIR140 mRNA] inhibits the reaction [Isoflurane results in increased expression of MIR140 mRNA]
MEG3 mRNA affects the reaction [Isoflurane results in decreased expression of MIR7-1 mRNA]; MIR7-1 mRNA affects the reaction [MEG3 mRNA affects the reaction [Isoflurane results in increased expression of IL1B protein]]; MIR7-1 mRNA affects the reaction [MEG3 mRNA affects the reaction [Isoflurane results in increased expression of IL6 protein]]; MIR7-1 mRNA affects the reaction [MEG3 mRNA affects the reaction [Isoflurane results in increased expression of TNF protein]]
Isoflurane results in increased expression of NFE2L2 protein NFE2L2 protein affects the reaction [trilobatin inhibits the reaction [Isoflurane results in decreased activity of CAT protein]]; trilobatin promotes the reaction [Isoflurane results in increased expression of NFE2L2 protein] 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Dexmedetomidine inhibits the reaction [Isoflurane results in decreased expression of NFE2L2 mRNA]]; 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Dexmedetomidine inhibits the reaction [Isoflurane results in decreased expression of NFE2L2 protein]]; 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Dexmedetomidine inhibits the reaction [Isoflurane results in decreased phosphorylation of NFE2L2 protein]]; Dexmedetomidine inhibits the reaction [Isoflurane results in decreased expression of NFE2L2 mRNA]; Dexmedetomidine inhibits the reaction [Isoflurane results in decreased expression of NFE2L2 protein]; Dexmedetomidine inhibits the reaction [Isoflurane results in decreased phosphorylation of NFE2L2 protein] Isoflurane results in decreased expression of NFE2L2 mRNA; Isoflurane results in decreased expression of NFE2L2 protein
Isoflurane results in increased expression of NLRP3 protein N-(1,2,3,5,6,7-hexahydro-S-indacen-4-ylcarbamoyl)-4-(2-hydroxy-2-propanyl)-2-furansulfonamide inhibits the reaction [Isoflurane results in increased expression of NLRP3 protein]; SETD7 protein affects the reaction [Isoflurane results in increased expression of NLRP3 protein]
Ditiocarb inhibits the reaction [Isoflurane results in increased expression of NOS2 protein]; S-methylisothiopseudouronium inhibits the reaction [Isoflurane results in increased expression of NOS2 protein]
trilobatin promotes the reaction [Isoflurane results in increased expression of NQO1 mRNA]; trilobatin promotes the reaction [Isoflurane results in increased expression of NQO1 protein] Isoflurane results in increased expression of NQO1 mRNA; Isoflurane results in increased expression of NQO1 protein
Isoflurane results in decreased expression of PYCARD mRNA N-(1,2,3,5,6,7-hexahydro-S-indacen-4-ylcarbamoyl)-4-(2-hydroxy-2-propanyl)-2-furansulfonamide inhibits the reaction [Isoflurane results in increased expression of PYCARD protein]; SETD7 protein affects the reaction [Isoflurane results in increased expression of PYCARD protein]
Isoflurane affects the activity of REN protein [Fentanyl co-treated with Isoflurane] results in decreased expression of REN protein; [Labetalol co-treated with Isoflurane] results in increased expression of REN protein
SETD7 protein affects the reaction [Isoflurane results in increased cleavage of CASP1 protein]; SETD7 protein affects the reaction [Isoflurane results in increased cleavage of GSDMD protein]; SETD7 protein affects the reaction [Isoflurane results in increased expression of IL18 protein]; SETD7 protein affects the reaction [Isoflurane results in increased expression of IL1B protein]; SETD7 protein affects the reaction [Isoflurane results in increased expression of IL6 protein]; SETD7 protein affects the reaction [Isoflurane results in increased expression of NLRP3 protein]; SETD7 protein affects the reaction [Isoflurane results in increased expression of PYCARD protein]; SETD7 protein affects the reaction [Isoflurane results in increased expression of TNF protein]
CAPN2 protein affects the reaction [Isoflurane results in decreased expression of SLC12A5 protein]; ifenprodil inhibits the reaction [Isoflurane results in decreased expression of SLC12A5 protein]
2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Dexmedetomidine inhibits the reaction [Isoflurane results in decreased expression of SOD1 protein]]; Dexmedetomidine inhibits the reaction [Isoflurane results in decreased expression of SOD1 protein]
5-hydroxydecanoic acid inhibits the reaction [Isoflurane results in decreased expression of and results in decreased activity of SOD2 protein]; Isoflurane results in decreased expression of and results in decreased activity of SOD2 protein; tempol inhibits the reaction [Isoflurane results in decreased expression of and results in decreased activity of SOD2 protein] resveratrol inhibits the reaction [Isoflurane results in decreased activity of SOD2 protein]
Isoflurane results in decreased expression of TNF mRNA; Isoflurane results in decreased expression of TNF protein Isoflurane results in increased expression of TNF mRNA; Isoflurane results in increased expression of TNF protein MEG3 mRNA affects the reaction [Isoflurane results in increased expression of TNF protein]; MIR7-1 mRNA affects the reaction [MEG3 mRNA affects the reaction [Isoflurane results in increased expression of TNF protein]]; rhodioloside inhibits the reaction [Isoflurane results in increased expression of TNF protein] MEG3 mRNA affects the reaction [Isoflurane results in increased expression of TNF protein]; SETD7 protein affects the reaction [Isoflurane results in increased expression of TNF protein]