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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:hexane-1,6-diamine
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Accession:CHEBI:39618 term browser browse the term
Definition:A C6 alkane-alpha,omega-diamine.
Synonyms:related_synonym: 1,6-diamino-n-hexane;   1,6-diaminohexane;   1,6-hexamethylenediamine;   1,6-hexanediamine;   1,6-hexylenediamine;   Formula=C6H16N2;   H2N(CH2)6NH2;   HEX-NH2;   HMDA;   InChI=1S/C6H16N2/c7-5-3-1-2-4-6-8/h1-8H2;   InChIKey=NAQMVNRVTILPCV-UHFFFAOYSA-N;   SMILES=NCCCCCCN;   diaminohexane;   hexamethylene diamine;   hexamethylenediamine;   hexylenediamine
 xref: Beilstein:1098307;   CAS:124-09-4;   DrugBank:DB03260;   Gmelin:2578
 xref_mesh: MESH:C007297
 xref: PDBeChem:16D;   PMID:21527495;   PMID:22986425;   PMID:23530439;   PMID:23933844;   PMID:24064415;   PMID:6182245;   Reaxys:1098307;   Wikipedia:Hexamethylenediamine



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hexane-1,6-diamine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adgrl3 adhesion G protein-coupled receptor L3 increases abundance ISO ADGRL3 gene modified form results in increased abundance of 1,6-diaminohexane CTD PMID:25445006 NCBI chr14:26,336,320...27,104,060
Ensembl chr14:26,368,277...27,105,860
JBrowse link
G Mpo myeloperoxidase multiple interactions ISO [1,6-diaminohexane binds to TEMPO] inhibits the reaction [MPO protein results in increased chemical synthesis of Hypochlorous Acid]; [1,6-diaminohexane binds to TEMPO] inhibits the reaction [MPO protein results in increased degradation of Hydrogen Peroxide]; [1,6-diaminohexane binds to TEMPO] inhibits the reaction [MPO protein results in increased oxidation of Nitric Oxide]; Heparin inhibits the reaction [[1,6-diaminohexane binds to TEMPO] inhibits the reaction [MPO protein results in increased chemical synthesis of Hypochlorous Acid]] CTD PMID:34085520 NCBI chr10:72,594,883...72,608,862
Ensembl chr10:72,594,661...72,604,819
JBrowse link
G Scara5 scavenger receptor class A, member 5 increases abundance ISO SCARA5 gene modified form results in increased abundance of 1,6-diaminohexane CTD PMID:25445006 NCBI chr15:39,880,017...39,985,007
Ensembl chr15:39,880,035...39,983,373
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19918
    role 19894
      application 19729
        solvent 17050
          non-polar solvent 8657
            hexane 435
              hexane-1,6-diamine 3
                N(1),N(6)-bis-DNCP-1,6-hexanediamine 0
                N-(2,4-dinitro-6-carboxy)phenyl-1.6-diaminohexane 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 19918
    subatomic particle 19916
      composite particle 19916
        hadron 19916
          baryon 19916
            nucleon 19916
              atomic nucleus 19916
                atom 19916
                  main group element atom 19866
                    main group molecular entity 19866
                      s-block molecular entity 19698
                        hydrogen molecular entity 19684
                          hydrides 19159
                            inorganic hydride 18151
                              pnictogen hydride 18140
                                nitrogen hydride 18046
                                  azane 17849
                                    ammonia 17848
                                      organic amino compound 17848
                                        polyamine 9031
                                          diamine 8966
                                            primary diamine 5708
                                              alkane-alpha,omega-diamine 3784
                                                hexane-1,6-diamine 3
                                                  N(1),N(6)-bis-DNCP-1,6-hexanediamine 0
                                                  N-(2,4-dinitro-6-carboxy)phenyl-1.6-diaminohexane 0
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