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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:cupressuflavone
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Accession:CHEBI:3960 term browser browse the term
Definition:A biflavonoid that is obtained by oxidative coupling of two molecules of apigenin resulting in a bond between positions C-8 of the two chromene rings respectively. Isolated from Cupressus sempervirens and Juniperus occidentalis, it exhibits free radical scavenging and antielastase activities.
Synonyms:exact_synonym: 5,5',7,7'-tetrahydroxy-2,2'-bis(4-hydroxyphenyl)-4H,4'H-8,8'-bichromene-4,4'-dione
 related_synonym: 4',4''',5,5'',7,7''-hexahydroxy-8-8''-biflavone;   8,8''-Biapigenin;   Formula=C30H18O10;   InChI=1S/C30H18O10/c31-15-5-1-13(2-6-15)23-11-21(37)25-17(33)9-19(35)27(29(25)39-23)28-20(36)10-18(34)26-22(38)12-24(40-30(26)28)14-3-7-16(32)8-4-14/h1-12,31-36H;   InChIKey=LADPNODMUXOPRG-UHFFFAOYSA-N;   SMILES=Oc1ccc(cc1)-c1cc(=O)c2c(O)cc(O)c(-c3c(O)cc(O)c4c3oc(cc4=O)-c3ccc(O)cc3)c2o1
 alt_id: CHEBI:65695
 xref: CAS:3952-18-9;   KEGG:C10034;   KNApSAcK:C00001034
 xref_mesh: MESH:C000600531
 xref: PMID:12372862;   PMID:12562084;   PMID:19280159;   Reaxys:1278120



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cupressuflavone term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Hexb hexosaminidase subunit beta multiple interactions ISO cupressuflavone inhibits the reaction [Oxazolone results in increased secretion of HEXB protein] CTD PMID:29258854 NCBI chr 2:28,483,997...28,504,165 JBrowse link
G Il4 interleukin 4 multiple interactions ISO cupressuflavone inhibits the reaction [Oxazolone results in increased secretion of IL4 protein] CTD PMID:29258854 NCBI chr10:38,272,003...38,277,549 JBrowse link

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  CHEBI ontology 19898
    role 19869
      biological role 19867
        biochemical role 19577
          metabolite 19563
            cupressuflavone 2
Path 2
Term Annotations click to browse term
  CHEBI ontology 19898
    subatomic particle 19896
      composite particle 19896
        hadron 19896
          baryon 19896
            nucleon 19896
              atomic nucleus 19896
                atom 19896
                  main group element atom 19835
                    p-block element atom 19835
                      carbon group element atom 19774
                        carbon atom 19770
                          organic molecular entity 19770
                            organic molecule 19724
                              organic cyclic compound 19516
                                organic heterocyclic compound 18896
                                  oxacycle 17924
                                    benzopyran 11981
                                      1-benzopyran 11735
                                        flavonoid 7234
                                          anthoxanthin 4586
                                            flavones 4586
                                              hydroxyflavone 4563
                                                cupressuflavone 2
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