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The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at The data is made available under the Creative Commons License (CC BY 3.0, For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

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Accession:CHEBI:3960 term browser browse the term
Definition:A biflavonoid that is obtained by oxidative coupling of two molecules of apigenin resulting in a bond between positions C-8 of the two chromene rings respectively. Isolated from Cupressus sempervirens and Juniperus occidentalis, it exhibits free radical scavenging and antielastase activities.
Synonyms:exact_synonym: 5,5',7,7'-tetrahydroxy-2,2'-bis(4-hydroxyphenyl)-4H,4'H-8,8'-bichromene-4,4'-dione
 related_synonym: 4',4''',5,5'',7,7''-hexahydroxy-8-8''-biflavone;   8,8''-Biapigenin;   Formula=C30H18O10;   InChI=1S/C30H18O10/c31-15-5-1-13(2-6-15)23-11-21(37)25-17(33)9-19(35)27(29(25)39-23)28-20(36)10-18(34)26-22(38)12-24(40-30(26)28)14-3-7-16(32)8-4-14/h1-12,31-36H;   InChIKey=LADPNODMUXOPRG-UHFFFAOYSA-N;   SMILES=Oc1ccc(cc1)-c1cc(=O)c2c(O)cc(O)c(-c3c(O)cc(O)c4c3oc(cc4=O)-c3ccc(O)cc3)c2o1
 alt_id: CHEBI:65695
 xref: CAS:3952-18-9;   KEGG:C10034;   KNApSAcK:C00001034
 xref_mesh: MESH:C000600531
 xref: PMID:12372862;   PMID:12562084;   PMID:19280159;   Reaxys:1278120

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cupressuflavone term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Hexb hexosaminidase subunit beta multiple interactions ISO cupressuflavone inhibits the reaction [Oxazolone results in increased secretion of HEXB protein] CTD PMID:29258854 NCBI chr 2:28,483,997...28,504,165
Ensembl chr 2:28,484,012...28,504,223
JBrowse link
G Il4 interleukin 4 multiple interactions ISO cupressuflavone inhibits the reaction [Oxazolone results in increased secretion of IL4 protein] CTD PMID:29258854 NCBI chr10:37,771,203...37,776,750
Ensembl chr10:37,771,203...37,776,750
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19812
    role 19784
      biological role 19782
        biochemical role 19495
          metabolite 19480
            cupressuflavone 2
Path 2
Term Annotations click to browse term
  CHEBI ontology 19812
    subatomic particle 19810
      composite particle 19810
        hadron 19810
          baryon 19810
            nucleon 19810
              atomic nucleus 19810
                atom 19810
                  main group element atom 19755
                    p-block element atom 19755
                      carbon group element atom 19698
                        carbon atom 19693
                          organic molecular entity 19693
                            organic molecule 19651
                              organic cyclic compound 19457
                                organic heterocyclic compound 18816
                                  oxacycle 17773
                                    benzopyran 11699
                                      1-benzopyran 11461
                                        flavonoid 6822
                                          anthoxanthin 4508
                                            flavones 4508
                                              hydroxyflavone 4494
                                                cupressuflavone 2
paths to the root