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The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at The data is made available under the Creative Commons License (CC BY 3.0, For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:12-hydroxylauric acid
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Accession:CHEBI:39567 term browser browse the term
Definition:A medium-chain fatty acid that is the 12-hydroxylated derivative of lauric acid.
Synonyms:related_synonym: 12-HYDROXYDODECANOIC ACID;   12-hydroxy lauric acid;   2-hydroxy-dodecanoic acid;   Formula=C12H24O3;   InChI=1S/C12H24O3/c13-11-9-7-5-3-1-2-4-6-8-10-12(14)15/h13H,1-11H2,(H,14,15);   InChIKey=ZDHCZVWCTKTBRY-UHFFFAOYSA-N;   SMILES=OCCCCCCCCCCCC(O)=O;   omega-Hydroxydodecanoic acid;   omega-OH dodecanoic acid;   omega-OH lauric acid;   omega-hydroxy lauric acid
 alt_id: CHEBI:10616;   CHEBI:39557
 xref: Beilstein:1238370;   CAS:505-95-3;   DrugBank:DB03704;   HMDB:HMDB0002059;   KEGG:C08317;   KNApSAcK:C00001219;   LIPID_MAPS_instance:LMFA01050039
 xref_mesh: MESH:C031263
 xref: PDBeChem:12H;   PMID:113393;   PMID:16719385;   PMID:2155662;   PMID:7872779;   Reaxys:1238370
 cyclic_relationship: is_conjugate_acid_of CHEBI:36204

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12-hydroxylauric acid term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adh5 alcohol dehydrogenase 5 (class III), chi polypeptide increases oxidation
affects binding
ISO ADH5 protein results in increased oxidation of 12-hydroxydodecanoic acid
12-hydroxydodecanoic acid binds to ADH5 protein
CTD PMID:12196016 PMID:12604204 PMID:19428350 NCBI chr 2:243,728,500...243,740,907
Ensembl chr 2:243,700,784...243,740,899
JBrowse link
G Cyp4v3 cytochrome P450, family 4, subfamily v, polypeptide 3 multiple interactions
increases chemical synthesis
ISO 2-chloro-5-nitrobenzanilide inhibits the reaction [CYP4V2 protein results in increased chemical synthesis of 12-hydroxydodecanoic acid] CTD PMID:28729181 NCBI chr16:50,111,803...50,136,741
Ensembl chr16:50,111,306...50,136,727
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19810
    role 19758
      biological role 19758
        antimicrobial agent 17329
          antibacterial agent 13028
            dodecanoic acid 164
              12-hydroxylauric acid 2
                (3R)-3,12-dihydroxylauric acid + 0
                oscr#20 + 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 19810
    subatomic particle 19808
      composite particle 19808
        hadron 19808
          baryon 19808
            nucleon 19808
              atomic nucleus 19808
                atom 19808
                  main group element atom 19696
                    p-block element atom 19696
                      carbon group element atom 19599
                        carbon atom 19588
                          organic molecular entity 19588
                            organic group 18527
                              organic divalent group 18520
                                organodiyl group 18520
                                  carbonyl group 18427
                                    carbonyl compound 18427
                                      carboxylic acid 18108
                                        monocarboxylic acid 17475
                                          fatty acid 15994
                                            saturated fatty acid 15967
                                              straight-chain saturated fatty acid 15418
                                                dodecanoic acid 164
                                                  12-hydroxylauric acid 2
                                                    (3R)-3,12-dihydroxylauric acid + 0
                                                    oscr#20 + 0
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