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ONTOLOGY REPORT - ANNOTATIONS


Term:2,2,2-tetramine
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Accession:CHEBI:39501 term browser browse the term
Definition:A polyazaalkane that is decane in which the carbon atoms at positions 1, 4, 7 and 10 are replaced by nitrogens.
Synonyms:exact_synonym: N,N'-bis(2-aminoethyl)ethane-1,2-diamine
 related_synonym: Formula=C6H18N4;   InChI=1S/C6H18N4/c7-1-3-9-5-6-10-4-2-8/h9-10H,1-8H2;   InChIKey=VILCJCGEZXAXTO-UHFFFAOYSA-N;   N,N'-BIS(2-AMINOETHYL)-1,2-ETHANEDIAMINE;   SMILES=NCCNCCNCCN;   TETA;   Trientine;   Triethylenetetramine;   trien;   triethylenetetraamine
 alt_id: CHEBI:39496;   CHEBI:9705
 xref: Beilstein:605448 "Beilstein";   CAS:112-24-3 "ChemIDplus";   CAS:112-24-3 "KEGG COMPOUND";   CAS:112-24-3 "NIST Chemistry WebBook";   Drug_Central:2738 "DrugCentral";   Gmelin:27008 "Gmelin";   KEGG:C07166
 xref_mesh: MESH:D014266
 xref: PDBeChem:104;   PMID:23024204 "Europe PMC";   PMID:24162190 "Europe PMC";   Reaxys:605448 "Reaxys";   Wikipedia:Trientine


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2,2,2-tetramine term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Acaca acetyl-CoA carboxylase alpha JBrowse link 10 71,519,392 71,719,910 RGD:6480464
G Acadm acyl-CoA dehydrogenase medium chain JBrowse link 2 260,124,418 260,148,589 RGD:6480464
G Acat1 acetyl-CoA acetyltransferase 1 JBrowse link 8 58,166,990 58,195,884 RGD:6480464
G Aco2 aconitase 2 JBrowse link 7 123,102,493 123,145,608 RGD:6480464
G Actc1 actin, alpha, cardiac muscle 1 JBrowse link 3 105,507,403 105,512,939 RGD:6480464
G Actn4 actinin alpha 4 JBrowse link 1 87,078,012 87,147,347 RGD:6480464
G Acy1 aminoacylase 1 JBrowse link 8 115,134,792 115,140,171 RGD:6480464
G Ager advanced glycosylation end product-specific receptor JBrowse link 20 4,363,152 4,366,079 RGD:6480464
G Agxt2 alanine-glyoxylate aminotransferase 2 JBrowse link 2 60,337,667 60,379,144 RGD:6480464
G Aifm1 apoptosis inducing factor, mitochondria associated 1 JBrowse link X 135,304,063 135,343,062 RGD:6480464
G Ak4 adenylate kinase 4 JBrowse link 5 120,250,318 120,309,153 RGD:6480464
G Akr1a1 aldo-keto reductase family 1 member A1 JBrowse link 5 135,482,068 135,498,693 RGD:6480464
G Aldob aldolase, fructose-bisphosphate B JBrowse link 5 64,805,772 64,818,813 RGD:6480464
G Anpep alanyl aminopeptidase, membrane JBrowse link 1 141,561,364 141,604,249 RGD:6480464
G Anxa3 annexin A3 JBrowse link 14 14,371,921 14,426,503 RGD:6480464
G Anxa5 annexin A5 JBrowse link 2 123,162,477 123,194,730 RGD:6480464
G Apoa1 apolipoprotein A1 JBrowse link 8 50,525,091 50,526,875 RGD:6480464
G App amyloid beta precursor protein JBrowse link 11 24,425,013 24,641,872 RGD:6480464
G Aqp1 aquaporin 1 JBrowse link 4 85,551,503 85,563,683 RGD:6480464
G Ass1 argininosuccinate synthase 1 JBrowse link 3 10,327,411 10,375,847 RGD:6480464
G Atp5f1a ATP synthase F1 subunit alpha JBrowse link 18 74,156,553 74,164,490 RGD:6480464
G Atp5f1b ATP synthase F1 subunit beta JBrowse link 7 2,504,708 2,511,748 RGD:6480464
G Atp5mf ATP synthase membrane subunit f JBrowse link 12 11,191,799 11,198,369 RGD:6480464
G Atp5po ATP synthase peripheral stalk subunit OSCP JBrowse link 11 32,081,606 32,087,918 RGD:6480464
G Atp6v1a ATPase H+ transporting V1 subunit A JBrowse link 11 61,531,386 61,584,634 RGD:6480464
G Atp6v1b2 ATPase H+ transporting V1 subunit B2 JBrowse link 16 22,326,537 22,350,143 RGD:6480464
G Atp7a ATPase copper transporting alpha JBrowse link X 77,076,085 77,193,644 RGD:6480464
G Bace1 beta-secretase 1 JBrowse link 8 50,140,092 50,162,388 RGD:6480464
G Bcl2 BCL2, apoptosis regulator JBrowse link 13 26,605,426 26,769,374 RGD:6480464
G Calm3 calmodulin 3 JBrowse link 1 78,844,520 78,851,628 RGD:6480464
G Calr calreticulin JBrowse link 19 25,956,771 25,961,666 RGD:6480464
G Casp3 caspase 3 JBrowse link 16 48,845,011 48,863,249 RGD:6480464
G Casp9 caspase 9 JBrowse link 5 160,356,211 160,373,774 RGD:6480464
G Ccs copper chaperone for superoxide dismutase JBrowse link 1 220,075,251 220,096,319 RGD:6480464
G Cisd1 CDGSH iron sulfur domain 1 JBrowse link 20 18,493,538 18,506,923 RGD:6480464
G Clu clusterin JBrowse link 15 42,626,612 42,665,858 RGD:6480464
G Col6a1 collagen type VI alpha 1 chain JBrowse link 20 12,657,913 12,676,370 RGD:6480464
G Col6a2 collagen type VI alpha 2 chain JBrowse link 20 12,773,472 12,801,179 RGD:6480464
G Col6a3 collagen type VI alpha 3 chain JBrowse link 9 97,926,784 98,004,643 RGD:6480464
G Cp ceruloplasmin JBrowse link 2 104,744,249 104,803,034 RGD:6480464
G Cpt2 carnitine palmitoyltransferase 2 JBrowse link 5 127,505,646 127,523,016 RGD:6480464
G Cryz crystallin zeta JBrowse link 2 260,884,315 260,911,827 RGD:6480464
G Cs citrate synthase JBrowse link 7 2,752,680 2,778,963 RGD:6480464
G Cyc1 cytochrome c-1 JBrowse link 7 117,409,576 117,411,953 RGD:6480464
G Cyp4a2 cytochrome P450, family 4, subfamily a, polypeptide 2 JBrowse link 5 134,196,910 134,207,888 RGD:6480464
G Dao D-amino-acid oxidase JBrowse link 12 48,353,691 48,373,647 RGD:6480464
G Dlat dihydrolipoamide S-acetyltransferase JBrowse link 8 55,062,549 55,087,832 RGD:6480464
G Dld dihydrolipoamide dehydrogenase JBrowse link 6 50,597,677 50,618,694 RGD:6480464
G Dlst dihydrolipoamide S-succinyltransferase JBrowse link 6 108,936,534 108,961,322 RGD:6480464
G Eno1-ps1 enolase 1, (alpha), pseudogene 1 JBrowse link 3 59,408,531 59,410,209 RGD:6480464
G Ephx1 epoxide hydrolase 1 JBrowse link 13 99,271,390 99,300,580 RGD:6480464
G Etfa electron transfer flavoprotein subunit alpha JBrowse link 8 60,028,786 60,086,352 RGD:6480464
G Etfb electron transfer flavoprotein subunit beta JBrowse link 1 98,472,776 98,486,940 RGD:6480464
G Fn1 fibronectin 1 JBrowse link 9 78,900,111 78,969,018 RGD:6480464
G Fxyd2 FXYD domain-containing ion transport regulator 2 JBrowse link 8 49,710,334 49,717,492 RGD:6480464
G G6pc glucose-6-phosphatase, catalytic subunit JBrowse link 10 89,286,009 89,296,213 RGD:6480464
G Gatm glycine amidinotransferase JBrowse link 3 114,711,570 114,728,155 RGD:6480464
G Ggt1 gamma-glutamyltransferase 1 JBrowse link 20 14,019,723 14,045,781 RGD:6480464
G Gng12 G protein subunit gamma 12 JBrowse link 4 97,634,925 97,763,478 RGD:6480464
G Got2 glutamic-oxaloacetic transaminase 2 JBrowse link 19 9,587,637 9,613,323 RGD:6480464
G Gpx1 glutathione peroxidase 1 JBrowse link 8 117,117,430 117,118,528 RGD:6480464
G Gpx3 glutathione peroxidase 3 JBrowse link 10 40,247,436 40,255,423 RGD:6480464
G Gsta2 glutathione S-transferase alpha 2 JBrowse link 8 85,640,081 85,645,621 RGD:6480464
G Gsta3 glutathione S-transferase alpha 3 JBrowse link 9 27,357,490 27,417,023 RGD:6480464
G Gstp1 glutathione S-transferase pi 1 JBrowse link 1 219,291,679 219,294,147 RGD:6480464
G Hao2 hydroxyacid oxidase 2 JBrowse link 2 200,785,492 200,808,868 RGD:6480464
G Hbb hemoglobin subunit beta JBrowse link 1 168,971,269 168,972,680 RGD:6480464
G Hmox1 heme oxygenase 1 JBrowse link 19 14,508,634 14,515,455 RGD:6480464
G Hsd17b10 hydroxysteroid (17-beta) dehydrogenase 10 JBrowse link X 21,696,796 21,699,241 RGD:6480464
G Hspa5 heat shock protein family A (Hsp70) member 5 JBrowse link 3 13,838,304 13,842,763 RGD:6480464
G Hspa9 heat shock protein family A (Hsp70) member 9 JBrowse link 18 27,731,072 27,749,235 RGD:6480464
G Hspd1 heat shock protein family D (Hsp60) member 1 JBrowse link 9 61,680,529 61,691,202 RGD:6480464
G Hspe1 heat shock protein family E (Hsp10) member 1 JBrowse link 9 61,691,246 61,724,948 RGD:6480464
G Hspg2 heparan sulfate proteoglycan 2 JBrowse link 5 155,812,096 155,913,751 RGD:6480464
G Ins2 insulin 2 JBrowse link 1 215,856,967 215,858,034 RGD:6480464
G Ldhb lactate dehydrogenase B JBrowse link 4 176,701,980 176,719,999 RGD:6480464
G Mdh1 malate dehydrogenase 1 JBrowse link 14 106,378,349 106,393,642 RGD:6480464
G Mdh2 malate dehydrogenase 2 JBrowse link 12 23,941,451 23,954,406 RGD:6480464
G Mme membrane metallo-endopeptidase JBrowse link 2 153,799,203 153,880,910 RGD:6480464
G Ndufa10 NADH:ubiquinone oxidoreductase subunit A10 JBrowse link 9 99,617,051 99,651,827 RGD:6480464
G Ndufab1 NADH:ubiquinone oxidoreductase subunit AB1 JBrowse link 1 192,044,209 192,057,644 RGD:6480464
G Ndufs2 NADH:ubiquinone oxidoreductase core subunit S2 JBrowse link 13 89,606,848 89,623,506 RGD:6480464
G Ndufs4 NADH:ubiquinone oxidoreductase subunit S4 JBrowse link 2 46,372,488 46,476,162 RGD:6480464
G Ndufv2 NADH:ubiquinone oxidoreductase core subunit V2 JBrowse link 9 113,875,718 113,900,169 RGD:6480464
G Nnt nicotinamide nucleotide transhydrogenase JBrowse link 2 52,189,523 52,283,095 RGD:6480464
G Oat ornithine aminotransferase JBrowse link 1 204,562,289 204,582,070 RGD:6480464
G Ogdh oxoglutarate dehydrogenase JBrowse link 14 86,414,924 86,481,903 RGD:6480464
G Pc pyruvate carboxylase JBrowse link 1 219,759,157 219,859,854 RGD:6480464
G Pck1 phosphoenolpyruvate carboxykinase 1 JBrowse link 3 171,213,936 171,219,885 RGD:6480464
G Phb prohibitin JBrowse link 10 83,476,107 83,488,878 RGD:6480464
G Podxl podocalyxin-like JBrowse link 4 58,829,049 58,893,353 RGD:6480464
G Ppia peptidylprolyl isomerase A JBrowse link 14 86,673,775 86,677,443 RGD:6480464
G Prnp prion protein JBrowse link 3 124,515,917 124,531,320 RGD:6480464
G Pyroxd2 pyridine nucleotide-disulphide oxidoreductase domain 2 JBrowse link 1 261,961,164 261,987,029 RGD:6480464
G Rela RELA proto-oncogene, NF-kB subunit JBrowse link 1 220,992,770 221,003,249 RGD:6480464
G Rps6 ribosomal protein S6 JBrowse link 5 105,197,821 105,200,681 RGD:6480464
G S100b S100 calcium binding protein B JBrowse link 20 13,130,633 13,142,856 RGD:6480464
G Sdha succinate dehydrogenase complex flavoprotein subunit A JBrowse link 1 31,545,631 31,570,601 RGD:6480464
G Sdhb succinate dehydrogenase complex iron sulfur subunit B JBrowse link 5 159,484,378 159,505,063 RGD:6480464
G Serpine1 serpin family E member 1 JBrowse link 12 22,641,104 22,651,482 RGD:6480464
G Sfxn1 sideroflexin 1 JBrowse link 17 11,046,588 11,082,219 RGD:6480464
G Slc22a6 solute carrier family 22 member 6 JBrowse link 1 224,824,809 224,833,284 RGD:6480464
G Slc25a10 solute carrier family 25 member 10 JBrowse link 10 109,665,682 109,674,782 RGD:6480464
G Slc25a3 solute carrier family 25 member 3 JBrowse link 7 31,816,601 31,824,064 RGD:6480464
G Slc25a5 solute carrier family 25 member 5 JBrowse link X 123,404,570 123,407,637 RGD:6480464
G Slc31a1 solute carrier family 31 member 1 JBrowse link 5 78,222,504 78,249,358 RGD:6480464
G Slc31a2 solute carrier family 31 member 2 JBrowse link 5 78,120,606 78,131,111 RGD:6480464
G Slc3a1 solute carrier family 3 member 1 JBrowse link 6 8,284,937 8,318,649 RGD:6480464
G Smad4 SMAD family member 4 JBrowse link 18 69,626,682 69,657,373 RGD:6480464
G Snap25 synaptosome associated protein 25 JBrowse link 3 129,697,408 129,788,417 RGD:6480464
G Sod1 superoxide dismutase 1 JBrowse link 11 30,363,282 30,368,858 RGD:6480464
G Sod2 superoxide dismutase 2 JBrowse link 1 47,914,757 47,921,587 RGD:6480464
G Sod3 superoxide dismutase 3 JBrowse link 14 60,958,583 60,971,143 RGD:6480464
G Syp synaptophysin JBrowse link X 15,694,699 15,709,244 RGD:6480464
G Tgfb1 transforming growth factor, beta 1 JBrowse link 1 82,480,875 82,497,196 RGD:6480464
G Tinag tubulointerstitial nephritis antigen JBrowse link 8 84,122,113 84,320,714 RGD:6480464
G Tp53 tumor protein p53 JBrowse link 10 56,186,299 56,198,449 RGD:6480464
G Ttr transthyretin JBrowse link 18 15,532,963 15,542,180 RGD:6480464
G Uba1 ubiquitin-like modifier activating enzyme 1 JBrowse link X 1,723,135 1,745,147 RGD:6480464
G Uqcrc1 ubiquinol-cytochrome c reductase core protein 1 JBrowse link 8 117,679,328 117,691,073 RGD:6480464
G Vdac1 voltage-dependent anion channel 1 JBrowse link 10 37,724,915 37,752,827 RGD:6480464
G Vdac2 voltage-dependent anion channel 2 JBrowse link 15 2,634,622 2,648,548 RGD:6480464

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19764
    role 19711
      application 19361
        refrigerant 17249
          ammonia 16698
            organic amino compound 16697
              polyamine 8083
                tetramine 184
                  2,2,2-tetramine 121
Path 2
Term Annotations click to browse term
  CHEBI ontology 19764
    subatomic particle 19762
      composite particle 19762
        hadron 19762
          baryon 19762
            nucleon 19762
              atomic nucleus 19762
                atom 19762
                  main group element atom 19646
                    main group molecular entity 19646
                      s-block molecular entity 19408
                        hydrogen molecular entity 19397
                          hydrides 18356
                            inorganic hydride 17210
                              pnictogen hydride 17174
                                nitrogen hydride 17008
                                  azane 16701
                                    ammonia 16698
                                      organic amino compound 16697
                                        polyamine 8083
                                          tetramine 184
                                            2,2,2-tetramine 121
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.