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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:aminoxyls
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Accession:CHEBI:39477 term browser browse the term
Definition:Radicals derived from hydroxylamines by removal of the hydrogen atom from the hydroxy group. The synonymous terms nitroxyl radicals and nitroxides erroneously suggest the presence of a nitro group.
Synonyms:related_synonym: aminoxyl radical;   nitroxides;   nitroxyl radicals



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4-amino-TEMPO term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Mpo myeloperoxidase multiple interactions ISO 4-amino-TEMPO inhibits the reaction [MPO protein results in increased chemical synthesis of Hypochlorous Acid]; 4-amino-TEMPO inhibits the reaction [MPO protein results in increased degradation of Hydrogen Peroxide]; 4-amino-TEMPO inhibits the reaction [MPO protein results in increased oxidation of Nitric Oxide]; Heparin inhibits the reaction [4-amino-TEMPO inhibits the reaction [MPO protein results in increased chemical synthesis of Hypochlorous Acid]] CTD PMID:34085520 NCBI chr10:72,594,883...72,608,862
Ensembl chr10:72,594,661...72,604,819
JBrowse link
4-carboxy-TEMPO term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Mpo myeloperoxidase multiple interactions ISO tempo carboxylic acid inhibits the reaction [MPO protein results in increased degradation of Hydrogen Peroxide] CTD PMID:34085520 NCBI chr10:72,594,883...72,608,862
Ensembl chr10:72,594,661...72,604,819
JBrowse link
4-hydroxy-TEMPO term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acta2 actin alpha 2, smooth muscle multiple interactions EXP tempol inhibits the reaction [Aldosterone results in increased expression of ACTA2 protein] CTD PMID:25204689 NCBI chr 1:231,746,527...231,759,307
Ensembl chr 1:231,746,548...231,759,554
JBrowse link
G Agt angiotensinogen multiple interactions EXP
ISO
tempol inhibits the reaction [AGT protein modified form results in increased expression of S1PR1 mRNA]; tempol inhibits the reaction [AGT protein modified form results in increased expression of S1PR1 protein]; tempol inhibits the reaction [AGT protein results in decreased export of Sodium]; tempol inhibits the reaction [AGT protein results in increased abundance of Oxygen]; tempol inhibits the reaction [Brimonidine Tartrate promotes the reaction [AGT protein results in increased abundance of Superoxides]]; tempol inhibits the reaction [Brimonidine Tartrate promotes the reaction [AGT protein results in increased expression of RHOA protein]]
tempol inhibits the reaction [[AGT protein modified form co-treated with AGTR1A co-treated with AGTR1B] results in increased expression of SERPINE1 mRNA]; tempol inhibits the reaction [AGT protein modified form results in increased abundance of Superoxides]; tempol inhibits the reaction [AGT protein results in increased expression of EDN1 mRNA]; tempol inhibits the reaction [ATP7A mutant form inhibits the reaction [AGT protein results in increased susceptibility to Acetylcholine]]; tempol inhibits the reaction [ATP7A mutant form promotes the reaction [AGT protein results in increased abundance of Superoxides]]; tempol promotes the reaction [ATOX1 protein inhibits the reaction [AGT protein modified form results in decreased susceptibility to Acetylcholine]]
CTD PMID:14597645 PMID:17391658 PMID:17620961 PMID:18250367 PMID:18768397 More... NCBI chr19:52,529,139...52,549,618
Ensembl chr19:52,529,185...52,540,977
JBrowse link
G Agtr1a angiotensin II receptor, type 1a multiple interactions ISO tempol inhibits the reaction [[AGT protein modified form co-treated with AGTR1A co-treated with AGTR1B] results in increased expression of SERPINE1 mRNA] CTD PMID:17620961 NCBI chr17:34,173,446...34,226,892
Ensembl chr17:34,174,429...34,226,946
JBrowse link
G Agtr1b angiotensin II receptor, type 1b multiple interactions ISO tempol inhibits the reaction [[AGT protein modified form co-treated with AGTR1A co-treated with AGTR1B] results in increased expression of SERPINE1 mRNA] CTD PMID:17620961 NCBI chr 2:102,844,969...102,920,232
Ensembl chr 2:102,844,969...102,920,232
JBrowse link
G Akt1 AKT serine/threonine kinase 1 affects phosphorylation ISO tempol affects the phosphorylation of AKT1 protein CTD PMID:24550650 NCBI chr 6:131,713,716...131,735,319
Ensembl chr 6:131,713,720...131,733,921
JBrowse link
G Apoe apolipoprotein E multiple interactions ISO tempol inhibits the reaction [APOE gene mutant form results in decreased susceptibility to Arachidonic Acid]
tempol inhibits the reaction [APOE gene mutant form promotes the reaction [Arachidonic Acid results in increased abundance of 11-dehydro-thromboxane B2]]
CTD PMID:20530721 NCBI chr 1:79,353,924...79,357,852
Ensembl chr 1:79,353,916...79,357,932
JBrowse link
G Atox1 antioxidant 1 copper chaperone multiple interactions ISO tempol promotes the reaction [ATOX1 protein inhibits the reaction [AGT protein modified form results in decreased susceptibility to Acetylcholine]] CTD PMID:22753205 NCBI chr10:39,564,855...39,579,892
Ensembl chr10:39,564,857...39,579,950
JBrowse link
G Atp7a ATPase copper transporting alpha multiple interactions ISO tempol inhibits the reaction [ATP7A mutant form inhibits the reaction [AGT protein results in increased susceptibility to Acetylcholine]]; tempol inhibits the reaction [ATP7A mutant form promotes the reaction [AGT protein results in increased abundance of Superoxides]] CTD PMID:18768397 NCBI chr  X:71,094,144...71,201,550
Ensembl chr  X:71,094,202...71,198,354
JBrowse link
G Bax BCL2 associated X, apoptosis regulator affects expression
decreases expression
ISO
EXP
tempol affects the expression of BAX protein
tempol results in decreased expression of BAX protein
CTD PMID:18714161 PMID:24550650 NCBI chr 1:95,940,001...95,945,407
Ensembl chr 1:95,938,808...95,945,368
JBrowse link
G Bcl2 BCL2, apoptosis regulator affects expression ISO tempol affects the expression of BCL2 protein CTD PMID:24550650 NCBI chr13:22,689,783...22,853,920
Ensembl chr13:22,684,989...22,853,743
Ensembl chr13:22,684,989...22,853,743
JBrowse link
G C1qa complement C1q A chain decreases expression ISO tempol results in decreased expression of C1QA mRNA CTD PMID:19555370 NCBI chr 5:149,133,635...149,136,482
Ensembl chr 5:149,133,636...149,136,534
JBrowse link
G C4b complement C4B decreases expression ISO tempol results in decreased expression of C4B mRNA CTD PMID:19555370 NCBI chr20:4,197,371...4,211,684
Ensembl chr20:4,197,366...4,211,681
JBrowse link
G Casp1 caspase 1 multiple interactions ISO tempol inhibits the reaction [7-ketocholesterol results in increased activity of CASP1 protein]; tempol inhibits the reaction [Cholesterol analog results in increased activity of CASP1 protein] CTD PMID:28633109 NCBI chr 8:2,587,812...2,597,403
Ensembl chr 8:2,587,831...2,597,383
JBrowse link
G Casp3 caspase 3 multiple interactions
decreases expression
ISO
EXP
[tempol co-treated with UCF 101 co-treated with acetovanillone] inhibits the reaction [S-Nitrosoglutathione results in increased activity of CASP3 protein]; tempol inhibits the reaction [[sulindac sulfide co-treated with TNF protein] results in increased activity of CASP3 protein]
tempol results in decreased expression of CASP3 protein
CTD PMID:18714161 PMID:20153346 PMID:20371263 NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648
JBrowse link
G Casp7 caspase 7 multiple interactions ISO tempol inhibits the reaction [[sulindac sulfide co-treated with TNF protein] results in increased activity of CASP7 protein]; tempol results in increased cleavage of and results in increased activity of CASP7 protein CTD PMID:20371263 PMID:26177467 NCBI chr 1:255,437,438...255,476,737
Ensembl chr 1:255,437,172...255,476,729
JBrowse link
G Casp9 caspase 9 decreases expression EXP tempol results in decreased expression of CASP9 protein CTD PMID:18714161 NCBI chr 5:154,108,872...154,126,628
Ensembl chr 5:154,109,046...154,126,626
JBrowse link
G Cat catalase multiple interactions EXP CAT protein results in increased susceptibility to [tert-Butylhydroperoxide co-treated with Desoxycorticosterone co-treated with tempol] CTD PMID:12646410 NCBI chr 3:89,842,393...89,874,577
Ensembl chr 3:89,842,399...89,874,478
JBrowse link
G Ccn2 cellular communication network factor 2 decreases expression EXP tempol results in decreased expression of CCN2 mRNA CTD PMID:16685210 NCBI chr 1:20,802,199...20,805,315
Ensembl chr 1:20,802,199...20,805,734
JBrowse link
G Ccnd1 cyclin D1 decreases expression ISO tempol results in decreased expression of CCND1 protein CTD PMID:26177467 NCBI chr 1:200,089,002...200,098,524
Ensembl chr 1:200,089,002...200,098,602
JBrowse link
G Cd38 CD38 molecule multiple interactions ISO tempol inhibits the reaction [Superoxides affects the localization of CD38 protein] CTD PMID:23940720 NCBI chr14:67,172,062...67,212,328
Ensembl chr14:67,172,063...67,211,986
JBrowse link
G Cdkn1a cyclin-dependent kinase inhibitor 1A multiple interactions
increases expression
ISO tempol promotes the reaction [CDKN1A protein results in increased susceptibility to Doxorubicin]
tempol results in increased expression of CDKN1A protein
CTD PMID:15601469 NCBI chr20:7,149,177...7,159,727
Ensembl chr20:7,149,217...7,159,585
JBrowse link
G Ctss cathepsin S decreases expression ISO tempol results in decreased expression of CTSS mRNA CTD PMID:19555370 NCBI chr 2:183,086,437...183,114,483
Ensembl chr 2:183,086,437...183,114,483
JBrowse link
G Cxcl14 C-X-C motif chemokine ligand 14 decreases expression ISO tempol results in decreased expression of CXCL14 mRNA CTD PMID:19555370 NCBI chr17:8,317,930...8,325,956
Ensembl chr17:8,317,933...8,324,839
JBrowse link
G Cyba cytochrome b-245 alpha chain decreases expression EXP tempol results in decreased expression of CYBA mRNA CTD PMID:16685210 NCBI chr19:50,487,598...50,495,669
Ensembl chr19:50,487,597...50,495,721
JBrowse link
G Cybb cytochrome b-245 beta chain decreases expression EXP tempol results in decreased expression of CYBB; tempol results in decreased expression of CYBB mRNA CTD PMID:16685210 PMID:20943769 NCBI chr  X:13,358,101...13,392,570
Ensembl chr  X:13,359,430...13,392,586
JBrowse link
G Cyp2e1 cytochrome P450, family 2, subfamily e, polypeptide 1 multiple interactions EXP tempol inhibits the reaction [CYP2E1 protein results in increased reduction of Tirapazamine] CTD PMID:7710944 NCBI chr 1:195,840,330...195,850,728
Ensembl chr 1:195,840,058...195,864,023
JBrowse link
G Edn1 endothelin 1 decreases expression
multiple interactions
EXP
ISO
tempol results in decreased expression of EDN1 mRNA; tempol results in decreased expression of EDN1 protein
tempol inhibits the reaction [AGT protein results in increased expression of EDN1 mRNA]
CTD PMID:17391658 PMID:28039404 NCBI chr17:22,454,924...22,460,812
Ensembl chr17:22,454,420...22,460,885
JBrowse link
G Epas1 endothelial PAS domain protein 1 affects localization ISO tempol affects the localization of EPAS1 protein CTD PMID:24755467 NCBI chr 6:7,790,236...7,871,717
Ensembl chr 6:7,790,647...7,871,228
JBrowse link
G Epo erythropoietin multiple interactions ISO tempol inhibits the reaction [sodium arsenate results in increased expression of EPO mRNA]; tempol inhibits the reaction [sodium arsenate results in increased expression of EPO protein] CTD PMID:36513130 NCBI chr12:19,204,258...19,207,948
Ensembl chr12:19,204,508...19,207,946
JBrowse link
G Fancd2 FA complementation group D2 decreases response to substance ISO tempol results in decreased susceptibility to FANCD2 gene mutant form CTD PMID:22628295 NCBI chr 4:146,679,014...146,743,422
Ensembl chr 4:146,679,179...146,743,412
JBrowse link
G Foxo3 forkhead box O3 affects phosphorylation ISO tempol affects the phosphorylation of FOXO3 protein CTD PMID:24550650 NCBI chr20:45,669,708...45,764,606
Ensembl chr20:45,672,995...45,764,561
JBrowse link
G Gclc glutamate-cysteine ligase, catalytic subunit multiple interactions EXP tempol inhibits the reaction [Aldosterone results in increased expression of GCLC protein] CTD PMID:24512358 PMID:25204689 NCBI chr 8:78,629,899...78,668,547
Ensembl chr 8:78,630,127...78,668,544
JBrowse link
G Gpx2 glutathione peroxidase 2 multiple interactions ISO [tempol co-treated with Tobacco Smoke Pollution] results in increased expression of GPX2 mRNA; tempol promotes the reaction [Tobacco Smoke Pollution results in increased expression of GPX2 protein] CTD PMID:32726580 NCBI chr 6:95,493,589...95,496,877
Ensembl chr 6:95,493,589...95,496,877
JBrowse link
G Gpx4 glutathione peroxidase 4 increases expression ISO tempol results in increased expression of GPX4 mRNA CTD PMID:22221582 NCBI chr 7:9,650,186...9,652,982
Ensembl chr 7:9,650,185...9,652,982
JBrowse link
G Gsr glutathione-disulfide reductase multiple interactions EXP tempol inhibits the reaction [Nitric Oxide deficiency results in increased expression of GSR protein] CTD PMID:15925750 NCBI chr16:58,482,209...58,525,256
Ensembl chr16:58,482,505...58,525,661
JBrowse link
G Hif1a hypoxia inducible factor 1 subunit alpha multiple interactions
increases expression
EXP tempol inhibits the reaction [Sodium Chloride results in increased expression of HIF1A protein]
tempol results in increased expression of HIF1A protein
CTD PMID:12595275 PMID:20232302 NCBI chr 6:92,624,059...92,669,262
Ensembl chr 6:92,624,390...92,669,261
JBrowse link
G Hmgcr 3-hydroxy-3-methylglutaryl-CoA reductase multiple interactions ISO tempol inhibits the reaction [Asbestos, Crocidolite results in decreased activity of HMGCR protein]; tempol inhibits the reaction [Vitamin K 3 results in decreased activity of HMGCR protein] CTD PMID:21257924 NCBI chr 2:27,997,523...28,018,983
Ensembl chr 2:27,997,525...28,019,703
JBrowse link
G Hmox1 heme oxygenase 1 increases expression
multiple interactions
EXP
ISO
tempol results in increased expression of HMOX1 mRNA
[tempol co-treated with Tobacco Smoke Pollution] results in increased expression of HMOX1 mRNA
CTD PMID:12595275 PMID:32726580 NCBI chr19:13,466,287...13,474,082
Ensembl chr19:13,467,244...13,474,079
JBrowse link
G Hspa5 heat shock protein family A (Hsp70) member 5 multiple interactions ISO tempol inhibits the reaction [PRKAA2 protein affects the expression of HSPA5 protein] CTD PMID:21145922 NCBI chr 3:18,055,507...18,059,969
Ensembl chr 3:18,055,405...18,059,891
JBrowse link
G Htra2 HtrA serine peptidase 2 multiple interactions ISO [tempol co-treated with UCF 101 co-treated with acetovanillone] inhibits the reaction [S-Nitrosoglutathione affects the localization of HTRA2 protein] CTD PMID:20153346 NCBI chr 4:115,556,914...115,560,202
Ensembl chr 4:115,556,916...115,560,095
JBrowse link
G Ikbke inhibitor of nuclear factor kappa B kinase subunit epsilon decreases expression ISO tempol results in decreased expression of IKBKE protein CTD PMID:26177467 NCBI chr13:42,712,154...42,738,470
Ensembl chr13:42,712,159...42,737,143
JBrowse link
G Il10 interleukin 10 multiple interactions ISO tempol inhibits the reaction [Tobacco Smoke Pollution results in decreased expression of IL10 mRNA] CTD PMID:32726580 NCBI chr13:42,472,625...42,477,308
Ensembl chr13:42,472,839...42,477,313
JBrowse link
G Il17a interleukin 17A multiple interactions ISO tempol inhibits the reaction [Tobacco Smoke Pollution results in increased expression of IL17A mRNA] CTD PMID:32726580 NCBI chr 9:23,144,402...23,147,889
Ensembl chr 9:23,144,402...23,147,889
JBrowse link
G Il1b interleukin 1 beta multiple interactions EXP
ISO
tempol inhibits the reaction [Phenol results in decreased expression of IL1B mRNA]
tempol inhibits the reaction [Tobacco Smoke Pollution results in increased expression of IL1B mRNA]
CTD PMID:16785328 PMID:32726580 NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415
JBrowse link
G Il6 interleukin 6 multiple interactions ISO tempol inhibits the reaction [Tobacco Smoke Pollution results in increased expression of IL6 mRNA]
tempol inhibits the reaction [2,2',4,4'-tetrabromodiphenyl ether results in increased expression of and results in increased secretion of IL6 protein]
CTD PMID:24296301 PMID:32726580 NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178
JBrowse link
G Ireb2 iron responsive element binding protein 2 increases expression ISO tempol results in increased expression of IREB2 protein CTD PMID:18073202 NCBI chr 8:55,228,080...55,311,613
Ensembl chr 8:55,228,085...55,311,611
JBrowse link
G Irs2 insulin receptor substrate 2 multiple interactions ISO tempol inhibits the reaction [Benzene results in decreased phosphorylation of IRS2 protein] CTD PMID:30346588 NCBI chr16:78,488,249...78,512,482
Ensembl chr16:78,485,045...78,512,482
JBrowse link
G Jun Jun proto-oncogene, AP-1 transcription factor subunit multiple interactions ISO tempol inhibits the reaction [Paraquat results in increased expression of JUN mRNA] CTD PMID:7662713 NCBI chr 5:109,894,175...109,897,268
Ensembl chr 5:109,893,145...109,897,656
JBrowse link
G Ldlr low density lipoprotein receptor multiple interactions ISO tempol inhibits the reaction [LDLR gene mutant form promotes the reaction [Arachidonic Acid results in increased abundance of 11-dehydro-thromboxane B2]] CTD PMID:20530721 NCBI chr 8:20,270,020...20,292,981
Ensembl chr 8:20,270,041...20,294,580
JBrowse link
G Lep leptin multiple interactions EXP tempol inhibits the reaction [LEP protein results in decreased activity of PON1 protein] CTD PMID:15829432 NCBI chr 4:57,661,127...57,675,262
Ensembl chr 4:57,661,131...57,675,262
JBrowse link
G Lepr leptin receptor multiple interactions ISO tempol inhibits the reaction [LEPR gene mutant form results in decreased susceptibility to Acetylcholine] CTD PMID:19478208 NCBI chr 5:116,294,409...116,477,904
Ensembl chr 5:116,289,823...116,475,908
JBrowse link
G Mapk1 mitogen activated protein kinase 1 multiple interactions
increases phosphorylation
EXP 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [tempol results in increased phosphorylation of MAPK1 protein] CTD PMID:20056918 NCBI chr11:83,957,813...84,023,629
Ensembl chr11:83,957,813...84,023,616
JBrowse link
G Mapk3 mitogen activated protein kinase 3 multiple interactions
increases phosphorylation
EXP 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [tempol results in increased phosphorylation of MAPK3 protein] CTD PMID:20056918 NCBI chr 1:181,366,646...181,372,863
Ensembl chr 1:181,366,637...181,372,863
JBrowse link
G Mir322 microRNA 322 multiple interactions ISO tempol inhibits the reaction [Glucose results in decreased expression of MIR322] CTD PMID:25516495 NCBI chr  X:132,806,594...132,806,688
Ensembl chr  X:132,806,594...132,806,688
JBrowse link
G Mmp2 matrix metallopeptidase 2 increases activity EXP tempol results in increased activity of MMP2 protein CTD PMID:17196988 NCBI chr19:14,154,657...14,182,870
Ensembl chr19:14,154,657...14,182,870
JBrowse link
G Mmp9 matrix metallopeptidase 9 increases activity EXP tempol results in increased activity of MMP9 protein CTD PMID:17196988 NCBI chr 3:153,684,158...153,692,118
Ensembl chr 3:153,683,858...153,692,120
JBrowse link
G Mpo myeloperoxidase multiple interactions ISO tempol inhibits the reaction [Tobacco Smoke Pollution results in increased expression of and results in increased activity of MPO protein] CTD PMID:32726580 NCBI chr10:72,594,883...72,608,862
Ensembl chr10:72,594,661...72,604,819
JBrowse link
G Nfe2l2 NFE2 like bZIP transcription factor 2 multiple interactions EXP tempol inhibits the reaction [Aldosterone results in increased activity of NFE2L2 protein] CTD PMID:25204689 NCBI chr 3:60,594,239...60,621,712
Ensembl chr 3:60,594,242...60,621,737
JBrowse link
G Nfkb1 nuclear factor kappa B subunit 1 multiple interactions EXP tempol inhibits the reaction [copper histidine results in increased activity of NFKB1 protein]; tempol inhibits the reaction [Copper results in increased activity of NFKB1 protein] CTD PMID:16987042 NCBI chr 2:224,016,214...224,132,135
Ensembl chr 2:224,016,214...224,110,404
JBrowse link
G Nfkbia NFKB inhibitor alpha multiple interactions ISO tempol inhibits the reaction [Particulate Matter results in decreased expression of NFKBIA protein] CTD PMID:27128347 NCBI chr 6:72,858,713...72,861,941
Ensembl chr 6:72,858,712...72,861,941
JBrowse link
G Nos1 nitric oxide synthase 1 multiple interactions
increases phosphorylation
EXP 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [tempol results in increased phosphorylation of NOS1 protein]; tempol inhibits the reaction [lead acetate results in increased expression of NOS1 protein]; tempol inhibits the reaction [Phenol results in decreased expression of NOS1 mRNA] CTD PMID:11454931 PMID:16785328 PMID:20056918 NCBI chr12:38,615,111...38,795,492
Ensembl chr12:38,626,714...38,710,945
JBrowse link
G Nos2 nitric oxide synthase 2 multiple interactions EXP tempol inhibits the reaction [copper histidine results in increased expression of NOS2 protein]; tempol inhibits the reaction [Copper results in increased expression of NOS2 protein]; tempol inhibits the reaction [lead acetate results in increased expression of NOS2 protein] CTD PMID:11454931 PMID:16987042 NCBI chr10:63,815,308...63,851,208
Ensembl chr10:63,815,308...63,851,210
JBrowse link
G Nos3 nitric oxide synthase 3 multiple interactions EXP
ISO
tempol inhibits the reaction [lead acetate results in increased expression of NOS3 protein]; tempol inhibits the reaction [Sodium Chloride results in decreased expression of NOS3 protein] CTD PMID:11230275 PMID:11454931 PMID:20232302 NCBI chr 4:10,793,834...10,814,170
Ensembl chr 4:10,793,834...10,814,166
JBrowse link
G Odc1 ornithine decarboxylase 1 multiple interactions ISO tempol inhibits the reaction [Paraquat results in increased activity of ODC1 protein] CTD PMID:7662713 NCBI chr 6:40,329,831...40,336,444
Ensembl chr 6:40,329,964...40,336,440
JBrowse link
G Pah phenylalanine hydroxylase decreases expression ISO tempol results in decreased expression of PAH mRNA CTD PMID:19555370 NCBI chr 7:21,933,179...21,998,134
Ensembl chr 7:21,933,179...21,998,130
JBrowse link
G Pecam1 platelet and endothelial cell adhesion molecule 1 multiple interactions ISO tempol inhibits the reaction [sodium arsenite results in increased expression of PECAM1 protein] CTD PMID:19033667 NCBI chr10:91,590,521...91,652,279
Ensembl chr10:91,590,521...91,652,116
JBrowse link
G Pon1 paraoxonase 1 multiple interactions EXP tempol inhibits the reaction [LEP protein results in decreased activity of PON1 protein] CTD PMID:15829432 NCBI chr 4:33,294,737...33,325,759
Ensembl chr 4:33,294,722...33,321,360
JBrowse link
G Prkaa2 protein kinase AMP-activated catalytic subunit alpha 2 multiple interactions ISO tempol inhibits the reaction [PRKAA2 protein affects the expression of HSPA5 protein] CTD PMID:21145922 NCBI chr 5:119,807,992...119,879,987
Ensembl chr 5:119,813,226...119,879,543
JBrowse link
G Prkg1 protein kinase cGMP-dependent 1 multiple interactions EXP tempol inhibits the reaction [Glucose results in decreased expression of PRKG1 protein] CTD PMID:17320767 NCBI chr 1:228,409,605...229,638,794
Ensembl chr 1:228,408,947...229,639,080
JBrowse link
G Prkn parkin RBR E3 ubiquitin protein ligase multiple interactions EXP tempol inhibits the reaction [Ketoconazole results in increased expression of PRKN mRNA]; tempol inhibits the reaction [Ketoconazole results in increased expression of PRKN protein] CTD PMID:25787151 NCBI chr 1:48,688,651...49,882,520
Ensembl chr 1:48,690,556...49,882,555
JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 multiple interactions EXP tempol inhibits the reaction [copper histidine results in increased expression of PTGS2 mRNA]; tempol inhibits the reaction [Copper results in increased expression of PTGS2 mRNA]; tempol inhibits the reaction [Lead results in increased expression of PTGS2 mRNA]; tempol inhibits the reaction [Mercuric Chloride results in increased expression of PTGS2 mRNA] CTD PMID:16987042 PMID:23415682 PMID:25596430 NCBI chr13:62,163,936...62,172,193
Ensembl chr13:62,163,932...62,172,188
JBrowse link
G Rela RELA proto-oncogene, NF-kB subunit multiple interactions ISO
EXP
tempol inhibits the reaction [Benzene results in increased phosphorylation of RELA protein]
tempol inhibits the reaction [copper histidine results in increased activity of RELA protein]; tempol inhibits the reaction [Copper results in increased activity of RELA protein]
CTD PMID:16987042 PMID:30346588 NCBI chr 1:202,925,001...202,935,484
Ensembl chr 1:202,924,945...202,935,484
JBrowse link
G Rhoa ras homolog family member A multiple interactions EXP
ISO
tempol inhibits the reaction [Brimonidine Tartrate promotes the reaction [AGT protein results in increased expression of RHOA protein]]
tempol inhibits the reaction [Asbestos, Crocidolite inhibits the reaction [RHOA protein binds to Guanosine Triphosphate]]; tempol inhibits the reaction [Asbestos, Crocidolite results in decreased prenylation of RHOA protein]; tempol inhibits the reaction [Vitamin K 3 inhibits the reaction [RHOA protein binds to Guanosine Triphosphate]]; tempol inhibits the reaction [Vitamin K 3 results in decreased prenylation of RHOA protein]
CTD PMID:18250367 PMID:21257924 NCBI chr 8:108,991,926...109,025,746
Ensembl chr 8:108,991,954...109,025,746
JBrowse link
G S1pr1 sphingosine-1-phosphate receptor 1 multiple interactions EXP tempol inhibits the reaction [AGT protein modified form results in increased expression of S1PR1 mRNA]; tempol inhibits the reaction [AGT protein modified form results in increased expression of S1PR1 protein] CTD PMID:29609002 NCBI chr 2:203,624,752...203,629,110
Ensembl chr 2:203,621,587...203,629,681
JBrowse link
G Serpine1 serpin family E member 1 multiple interactions ISO tempol inhibits the reaction [[AGT protein modified form co-treated with AGTR1A co-treated with AGTR1B] results in increased expression of SERPINE1 mRNA]; tempol inhibits the reaction [Hydrogen Peroxide results in increased expression of SERPINE1 mRNA] CTD PMID:17620961 NCBI chr12:19,601,272...19,611,657
Ensembl chr12:19,601,272...19,611,657
JBrowse link
G Skap2 src kinase associated phosphoprotein 2 decreases expression ISO tempol results in decreased expression of SKAP2 mRNA CTD PMID:19555370 NCBI chr 4:80,948,832...81,100,900
Ensembl chr 4:80,950,580...81,100,891
JBrowse link
G Slc12a2 solute carrier family 12 member 2 multiple interactions EXP tempol inhibits the reaction [Manganese results in increased expression of SLC12A2 protein]; tempol inhibits the reaction [Manganese results in increased oxidation of SLC12A2 protein] CTD PMID:25817889 NCBI chr18:51,348,282...51,416,448
Ensembl chr18:51,348,302...51,416,440
JBrowse link
G Socs1 suppressor of cytokine signaling 1 multiple interactions ISO tempol inhibits the reaction [Benzene results in increased expression of SOCS1 mRNA] CTD PMID:30346588 NCBI chr10:4,882,651...4,884,342
Ensembl chr10:4,882,560...4,884,383
JBrowse link
G Sod1 superoxide dismutase 1 multiple interactions EXP tempol inhibits the reaction [Desoxycorticosterone results in decreased expression of SOD1 protein] CTD PMID:12646410 NCBI chr11:29,456,673...29,462,249
Ensembl chr11:29,456,558...29,462,249
JBrowse link
G Sod2 superoxide dismutase 2 affects expression
multiple interactions
ISO
EXP
tempol affects the expression of SOD2 protein
tempol affects the reaction [SOD2 protein affects the susceptibility to Acetylcholine]; tempol inhibits the reaction [Capsaicin results in decreased activity of SOD2 protein]; tempol inhibits the reaction [Capsaicin results in increased expression of SOD2 protein modified form]
tempol inhibits the reaction [Isoflurane results in decreased expression of and results in decreased activity of SOD2 protein]; tempol inhibits the reaction [Nitric Oxide deficiency results in increased expression of SOD2 protein]
CTD PMID:15925750 PMID:17693941 PMID:19129394 PMID:20304815 PMID:24550650 NCBI chr 1:47,638,318...47,645,163
Ensembl chr 1:47,636,528...47,645,189
JBrowse link
G Tfrc transferrin receptor increases expression ISO tempol results in increased expression of TFRC protein CTD PMID:18073202 NCBI chr11:68,163,413...68,185,257
Ensembl chr11:68,163,413...68,185,257
JBrowse link
G Tgfb1 transforming growth factor, beta 1 affects expression
multiple interactions
ISO
EXP
tempol affects the expression of TGFB1 protein
tempol inhibits the reaction [Tobacco Smoke Pollution results in decreased expression of TGFB1 mRNA]
tempol inhibits the reaction [Aldosterone results in increased expression of TGFB1 mRNA]; tempol inhibits the reaction [Sodium Chloride results in increased expression of TGFB1 protein]
CTD PMID:20232302 PMID:24550650 PMID:25204689 PMID:32726580 NCBI chr 1:81,196,532...81,212,848
Ensembl chr 1:81,196,532...81,212,847
JBrowse link
G Tnf tumor necrosis factor multiple interactions ISO
EXP
tempol inhibits the reaction [[sulindac sulfide co-treated with TNF protein] results in increased activity of CASP3 protein]; tempol inhibits the reaction [[sulindac sulfide co-treated with TNF protein] results in increased activity of CASP7 protein]
tempol inhibits the reaction [Lipopolysaccharides results in increased expression of TNF protein]; tempol inhibits the reaction [Tobacco Smoke Pollution results in increased expression of TNF mRNA]
tempol inhibits the reaction [copper histidine results in increased expression of TNF protein]; tempol inhibits the reaction [Copper results in increased expression of TNF protein]
CTD PMID:15795323 PMID:16987042 PMID:20371263 PMID:32726580 NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629
JBrowse link
G Tp53 tumor protein p53 increases expression ISO tempol results in increased expression of TP53 protein CTD PMID:15601469 NCBI chr10:54,300,070...54,311,525
Ensembl chr10:54,300,048...54,311,524
JBrowse link
G Traf3 Tnf receptor-associated factor 3 multiple interactions ISO tempol inhibits the reaction [Glucose results in increased expression of TRAF3 protein] CTD PMID:25516495 NCBI chr 6:130,199,696...130,307,168
Ensembl chr 6:130,206,484...130,305,481
JBrowse link
G Trpm4 transient receptor potential cation channel, subfamily M, member 4 multiple interactions ISO tempol inhibits the reaction [Arsenic Trioxide results in increased expression of TRPM4 protein] CTD PMID:31054354 NCBI chr 1:95,781,805...95,812,095
Ensembl chr 1:95,782,000...95,812,532
JBrowse link
G Ucp2 uncoupling protein 2 decreases expression
increases expression
EXP tempol results in decreased expression of UCP2 mRNA
tempol results in increased expression of UCP2 protein
CTD PMID:16685210 PMID:24591154 NCBI chr 1:154,839,242...154,845,612
Ensembl chr 1:154,839,209...154,845,611
JBrowse link
4-methoxy-TEMPO term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Chek1 checkpoint kinase 1 increases phosphorylation ISO 4-methoxy-2,2,6,6-tetramethylpiperidinyl-1-oxy results in increased phosphorylation of CHEK1 protein CTD PMID:28993908 NCBI chr 8:36,420,565...36,443,477
Ensembl chr 8:36,420,569...36,441,009
JBrowse link
G Chek2 checkpoint kinase 2 increases phosphorylation ISO 4-methoxy-2,2,6,6-tetramethylpiperidinyl-1-oxy results in increased phosphorylation of CHEK2 protein CTD PMID:28993908 NCBI chr12:45,788,823...45,821,382
Ensembl chr12:45,788,827...45,821,286
JBrowse link
G H2ax H2A.X variant histone increases phosphorylation
multiple interactions
ISO 4-methoxy-2,2,6,6-tetramethylpiperidinyl-1-oxy results in increased phosphorylation of H2AX protein
Acetylcysteine inhibits the reaction [4-methoxy-2,2,6,6-tetramethylpiperidinyl-1-oxy results in increased phosphorylation of H2AX protein]; pyrazolanthrone inhibits the reaction [4-methoxy-2,2,6,6-tetramethylpiperidinyl-1-oxy results in increased phosphorylation of H2AX protein]
CTD PMID:28993908 NCBI chr 8:44,671,907...44,673,262
Ensembl chr 8:44,671,786...44,673,239
JBrowse link
G Map1lc3b microtubule-associated protein 1 light chain 3 beta increases metabolic processing ISO 4-methoxy-2,2,6,6-tetramethylpiperidinyl-1-oxy results in increased metabolism of MAP1LC3B protein CTD PMID:28993908 NCBI chr19:49,665,795...49,673,655
Ensembl chr19:49,665,791...49,677,690
JBrowse link
G Mapk1 mitogen activated protein kinase 1 multiple interactions
increases phosphorylation
ISO U 0126 inhibits the reaction [4-methoxy-2,2,6,6-tetramethylpiperidinyl-1-oxy results in increased phosphorylation of MAPK1 protein] CTD PMID:28993908 NCBI chr11:83,957,813...84,023,629
Ensembl chr11:83,957,813...84,023,616
JBrowse link
G Mapk3 mitogen activated protein kinase 3 increases phosphorylation
multiple interactions
ISO 4-methoxy-2,2,6,6-tetramethylpiperidinyl-1-oxy results in increased phosphorylation of MAPK3 protein
U 0126 inhibits the reaction [4-methoxy-2,2,6,6-tetramethylpiperidinyl-1-oxy results in increased phosphorylation of MAPK3 protein]
CTD PMID:28993908 NCBI chr 1:181,366,646...181,372,863
Ensembl chr 1:181,366,637...181,372,863
JBrowse link
G Sqstm1 sequestosome 1 decreases expression ISO 4-methoxy-2,2,6,6-tetramethylpiperidinyl-1-oxy results in decreased expression of SQSTM1 protein CTD PMID:28993908 NCBI chr10:34,525,517...34,536,670
Ensembl chr10:34,525,519...34,536,673
JBrowse link
TEMPO term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bak1 BCL2-antagonist/killer 1 multiple interactions EXP TEMPO inhibits the reaction [nickel sulfate results in increased expression of BAK1 mRNA]; TEMPO inhibits the reaction [nickel sulfate results in increased expression of BAK1 protein] CTD PMID:28296042 NCBI chr20:5,100,480...5,109,669
Ensembl chr20:5,100,480...5,109,264
JBrowse link
G Bcl2 BCL2, apoptosis regulator decreases expression ISO TEMPO results in decreased expression of BCL2 protein CTD PMID:25882087 NCBI chr13:22,689,783...22,853,920
Ensembl chr13:22,684,989...22,853,743
Ensembl chr13:22,684,989...22,853,743
JBrowse link
G Bcl2l1 Bcl2-like 1 multiple interactions
decreases expression
EXP
ISO
TEMPO inhibits the reaction [Hexachlorocyclohexane results in increased expression of BCL2L1 protein]
TEMPO results in decreased expression of BCL2L1 protein
CTD PMID:22001173 PMID:25882087 NCBI chr 3:141,253,508...141,304,582
Ensembl chr 3:141,253,523...141,303,479
JBrowse link
G Casp12 caspase 12 multiple interactions EXP TEMPO inhibits the reaction [nickel sulfate results in increased expression of CASP12 mRNA]; TEMPO inhibits the reaction [nickel sulfate results in increased expression of CASP12 protein] CTD PMID:28296042 NCBI chr 8:2,642,296...2,669,549
Ensembl chr 8:2,642,434...2,674,037
JBrowse link
G Casp3 caspase 3 multiple interactions
increases activity
EXP
ISO
TEMPO inhibits the reaction [Hexachlorocyclohexane results in increased activity of CASP3 protein]; TEMPO inhibits the reaction [nickel sulfate results in increased expression of CASP3 protein]
pyrazolanthrone inhibits the reaction [TEMPO results in increased activity of CASP3 protein]
CTD PMID:22001173 PMID:25882087 PMID:28296042 NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648
JBrowse link
G Casp7 caspase 7 increases activity
multiple interactions
ISO TEMPO results in increased activity of CASP7 protein
pyrazolanthrone inhibits the reaction [TEMPO results in increased activity of CASP7 protein]
CTD PMID:25882087 NCBI chr 1:255,437,438...255,476,737
Ensembl chr 1:255,437,172...255,476,729
JBrowse link
G Casp9 caspase 9 multiple interactions EXP TEMPO inhibits the reaction [Hexachlorocyclohexane results in increased activity of CASP9 protein]; TEMPO inhibits the reaction [nickel sulfate results in increased expression of CASP9 mRNA]; TEMPO inhibits the reaction [nickel sulfate results in increased expression of CASP9 protein] CTD PMID:22001173 PMID:28296042 NCBI chr 5:154,108,872...154,126,628
Ensembl chr 5:154,109,046...154,126,626
JBrowse link
G Cycs cytochrome c, somatic multiple interactions EXP TEMPO inhibits the reaction [nickel sulfate results in increased expression of CYCS mRNA] CTD PMID:28296042 NCBI chr 4:79,651,894...79,653,994
Ensembl chr 4:79,651,378...79,654,054
Ensembl chr18:79,651,378...79,654,054
JBrowse link
G Ddit3 DNA-damage inducible transcript 3 multiple interactions EXP TEMPO inhibits the reaction [nickel sulfate results in increased expression of DDIT3 mRNA]; TEMPO inhibits the reaction [nickel sulfate results in increased expression of DDIT3 protein] CTD PMID:28296042 NCBI chr 7:63,115,645...63,121,203
Ensembl chr 7:63,116,380...63,121,201
JBrowse link
G H2ax H2A.X variant histone increases expression ISO TEMPO results in increased expression of H2AX protein CTD PMID:25882087 NCBI chr 8:44,671,907...44,673,262
Ensembl chr 8:44,671,786...44,673,239
JBrowse link
G Hmox1 heme oxygenase 1 multiple interactions ISO TEMPO inhibits the reaction [Raloxifene Hydrochloride results in increased expression of HMOX1 mRNA] CTD PMID:20888885 NCBI chr19:13,466,287...13,474,082
Ensembl chr19:13,467,244...13,474,079
JBrowse link
G Hspa5 heat shock protein family A (Hsp70) member 5 multiple interactions EXP TEMPO inhibits the reaction [nickel sulfate results in increased expression of HSPA5 mRNA]; TEMPO inhibits the reaction [nickel sulfate results in increased expression of HSPA5 protein] CTD PMID:28296042 NCBI chr 3:18,055,507...18,059,969
Ensembl chr 3:18,055,405...18,059,891
JBrowse link
G Mapk8 mitogen-activated protein kinase 8 multiple interactions ISO TEMPO inhibits the reaction [Acetaminophen results in increased phosphorylation of MAPK8 protein] CTD PMID:33290831 NCBI chr16:8,638,897...8,721,960
Ensembl chr16:8,638,924...8,721,981
JBrowse link
G Mapk9 mitogen-activated protein kinase 9 multiple interactions ISO TEMPO inhibits the reaction [Acetaminophen results in increased phosphorylation of MAPK9 protein] CTD PMID:33290831 NCBI chr10:34,169,661...34,211,138
Ensembl chr10:34,169,675...34,210,178
JBrowse link
G Mcl1 MCL1 apoptosis regulator, BCL2 family member decreases expression ISO TEMPO results in decreased expression of MCL1 protein CTD PMID:25882087 NCBI chr 2:183,219,137...183,235,676
Ensembl chr 2:183,219,220...183,222,303
JBrowse link
G Mpo myeloperoxidase multiple interactions ISO [1,6-diaminohexane binds to TEMPO] inhibits the reaction [MPO protein results in increased chemical synthesis of Hypochlorous Acid]; [1,6-diaminohexane binds to TEMPO] inhibits the reaction [MPO protein results in increased degradation of Hydrogen Peroxide]; [1,6-diaminohexane binds to TEMPO] inhibits the reaction [MPO protein results in increased oxidation of Nitric Oxide]; [Cadaverine binds to TEMPO] inhibits the reaction [MPO protein results in increased chemical synthesis of Hypochlorous Acid]; [Cadaverine binds to TEMPO] inhibits the reaction [MPO protein results in increased degradation of Hydrogen Peroxide]; [Cadaverine binds to TEMPO] inhibits the reaction [MPO protein results in increased oxidation of Nitric Oxide]; [ethylenediamine binds to TEMPO] inhibits the reaction [MPO protein results in increased chemical synthesis of Hypochlorous Acid]; [ethylenediamine binds to TEMPO] inhibits the reaction [MPO protein results in increased degradation of Hydrogen Peroxide]; [ethylenediamine binds to TEMPO] inhibits the reaction [MPO protein results in increased oxidation of Nitric Oxide]; [Putrescine binds to TEMPO] inhibits the reaction [MPO protein results in increased chemical synthesis of Hypochlorous Acid]; [Putrescine binds to TEMPO] inhibits the reaction [MPO protein results in increased degradation of Hydrogen Peroxide]; [Putrescine binds to TEMPO] inhibits the reaction [MPO protein results in increased oxidation of Nitric Oxide]; [Spermine binds to TEMPO] inhibits the reaction [MPO protein results in increased chemical synthesis of Hypochlorous Acid]; [Spermine binds to TEMPO] inhibits the reaction [MPO protein results in increased degradation of Hydrogen Peroxide]; [Spermine binds to TEMPO] inhibits the reaction [MPO protein results in increased oxidation of Nitric Oxide]; [trimethylenediamine binds to TEMPO] inhibits the reaction [MPO protein results in increased chemical synthesis of Hypochlorous Acid]; [trimethylenediamine binds to TEMPO] inhibits the reaction [MPO protein results in increased degradation of Hydrogen Peroxide]; [trimethylenediamine binds to TEMPO] inhibits the reaction [MPO protein results in increased oxidation of Nitric Oxide]; Heparin inhibits the reaction [[1,6-diaminohexane binds to TEMPO] inhibits the reaction [MPO protein results in increased chemical synthesis of Hypochlorous Acid]]; Heparin inhibits the reaction [[Cadaverine binds to TEMPO] inhibits the reaction [MPO protein results in increased chemical synthesis of Hypochlorous Acid]]; Heparin inhibits the reaction [[Putrescine binds to TEMPO] inhibits the reaction [MPO protein results in increased chemical synthesis of Hypochlorous Acid]]; Heparin inhibits the reaction [[Spermine binds to TEMPO] inhibits the reaction [MPO protein results in increased chemical synthesis of Hypochlorous Acid]]; Heparin inhibits the reaction [[trimethylenediamine binds to TEMPO] inhibits the reaction [MPO protein results in increased chemical synthesis of Hypochlorous Acid]] CTD PMID:34085520 NCBI chr10:72,594,883...72,608,862
Ensembl chr10:72,594,661...72,604,819
JBrowse link
G Msr1 macrophage scavenger receptor 1 multiple interactions ISO TEMPO inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of MSR1 mRNA alternative form]; TEMPO inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of MSR1 mRNA] CTD PMID:9614211 NCBI chr16:52,717,775...52,803,602
Ensembl chr16:52,717,732...52,799,676
JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 multiple interactions ISO TEMPO inhibits the reaction [Sodium Chloride results in increased expression of PTGS2 protein] CTD PMID:16024921 NCBI chr13:62,163,936...62,172,193
Ensembl chr13:62,163,932...62,172,188
JBrowse link
G Star steroidogenic acute regulatory protein multiple interactions EXP TEMPO inhibits the reaction [nickel sulfate results in decreased expression of STAR mRNA]; TEMPO inhibits the reaction [nickel sulfate results in decreased expression of STAR protein] CTD PMID:29567110 NCBI chr16:66,267,094...66,274,368
Ensembl chr16:66,264,807...66,271,672
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19860
    chemical entity 19858
      molecular entity 19858
        radical 490
          organic radical 118
            aminoxyls 102
              (1-oxyl-2,2,5,5-tetramethylpyrroline-3-methyl)methanethiosulfonate 0
              1-(4-azido-2-nitrophenyl)amino-3-(1-oxyl-2,2,5,5-pyrrolidin-3-ylcarbonylamino)propan-2-yl diphosphate 0
              16-DOXYL-stearic acid + 0
              16-DOXYL-stearic acid methyl ester 0
              2-[(2-\{[2-(\{2,4-dinitro-5-[2,2,6,6-tetramethyl-1-(ylooxy)piperidin-4-ylamino]phenyl\}amino)ethyl]amino\}-2-oxoethoxy)acetamido]ethyl 1,2-dipalmitoylglycero-3-phosphate 0
              3-(2-iodacetamido)-PROXYL 0
              3-(aminomethyl)-PROXYL 0
              3-[2-(2-bromoacetamido)acetamide]-PROXYL 0
              3-carbamoyl-PROXYL 0
              3-carboxy-PROXYL 0
              3-cyano-PROXYL 0
              3-maleimido-PROXYL 0
              4,4-dimethyloxazolidine-N-oxyl + 0
              4-(2-iodacetamido)-TEMPO 0
              4-(\{5-[(2-aminoethyl)amino]-2,4-dinitrophenyl\}amino)-TEMPO 0
              4-acetamido-TEMPO 0
              4-amino-TEMPO + 1
              4-carboxy-TEMPO 1
              4-hydroxy-TEMPO + 87
              4-hydroxy-TEMPO benzoate 0
              4-maleimido-TEMPO 0
              4-methacryloyloxy-TEMPO 0
              4-methoxy-TEMPO 7
              4-oxo-TEMPO 0
              5-DOXYL-stearic acid + 0
              5-DOXYL-stearic acid methyl ester 0
              PROXYL + 0
              TEMPO + 102
              TOAC 0
              XJB-5-131 0
              di-tert-butyl nitroxide 0
              potassium nitrosodisulfonate 0
paths to the root