CHEBI ONTOLOGY - ANNOTATIONS
The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/ . The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/ ). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term: benzilic acid
Accession: CHEBI:39414
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Definition: A 2-hydroxy monocarboxylic acid that has formula C14H12O3.
Synonyms: exact_synonym: hydroxy(diphenyl)acetic acid
related_synonym: 2-hydroxy-2,2-diphenylacetic acid; Benzilsaeure; Formula=C14H12O3; InChI=1S/C14H12O3/c15-13(16)14(17,11-7-3-1-4-8-11)12-9-5-2-6-10-12/h1-10,17H,(H,15,16); InChIKey=UKXSKSHDVLQNKG-UHFFFAOYSA-N; SMILES=OC(=O)C(O)(c1ccccc1)c1ccccc1; acide diphenylhydroxyacetique; alpha,alpha-diphenyl-alpha-hydroxyacetic acid; alpha,alpha-diphenylglycolic acid; alpha-hydroxy-2,2-diphenylacetic acid; alpha-hydroxy-alpha-phenylbenzeneacetic acid; alpha-phenylmandelic acid; diphenylglycolic acid
xref: Beilstein:521402; CAS:76-93-7; Gmelin:281752
G
Ar
androgen receptor
multiple interactions
ISO
Dihydrotestosterone inhibits the reaction [chloropropylate results in increased activity of AR protein]
CTD
PMID:15064155
NCBI chr X:67,656,253...67,828,998
Ensembl chr X:67,656,253...67,829,026
G
Esr1
estrogen receptor 1
increases activity
ISO
chloropropylate results in increased activity of ESR1 protein
CTD
PMID:15064155
NCBI chr 1:41,192,029...41,594,799
Ensembl chr 1:41,192,824...41,594,796
G
Esr2
estrogen receptor 2
increases activity
ISO
chloropropylate results in increased activity of ESR2 protein
CTD
PMID:15064155
NCBI chr 6:99,163,953...99,214,711
Ensembl chr 6:99,164,357...99,214,251
G
Nr1i2
nuclear receptor subfamily 1, group I, member 2
multiple interactions
ISO
chloropropylate binds to and results in increased activity of NR1I2 protein
CTD
PMID:21115097
NCBI chr11:65,022,100...65,058,546
Ensembl chr11:65,022,100...65,058,545
G
Slc22a2
solute carrier family 22 member 2
multiple interactions
ISO
clidinium inhibits the reaction [SLC22A2 protein results in increased uptake of 4-(4-dimethylaminostyryl)-1-methylpyridinium]
CTD
PMID:21599003
NCBI chr 1:48,318,025...48,360,219
Ensembl chr 1:48,317,995...48,360,261
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