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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:phthalimide insecticide
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Accession:CHEBI:39398 term browser browse the term
Synonyms:related_synonym: phthalimide insecticides


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tetramethrin term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ar androgen receptor multiple interactions
decreases expression
ISO tetramethrin results in decreased activity of [Dihydrotestosterone results in increased activity of AR protein]
tetramethrin results in decreased expression of AR mRNA
CTD PMID:12711008 PMID:16621434 NCBI chr  X:98,148,757...98,323,218
Ensembl chr  X:98,148,769...98,323,215
JBrowse link
G Brca1 breast cancer 1, early onset affects binding ISO tetramethrin binds to BRCA1 protein CTD PMID:32278787 NCBI chr11:101,488,761...101,551,955
Ensembl chr11:101,488,764...101,551,955
JBrowse link
G Ces2h carboxylesterase 2H multiple interactions
increases metabolic processing
ISO CES2 protein inhibits the reaction [tetramethrin results in increased activity of NR1I2 protein]
CES2 protein results in increased metabolism of tetramethrin
CTD PMID:19249324 NCBI chr 8:105,000,830...105,020,410
Ensembl chr 8:105,000,853...105,021,178
JBrowse link
G Esr1 estrogen receptor 1 (alpha) decreases expression ISO tetramethrin results in decreased expression of ESR1 protein CTD PMID:16326440 NCBI chr10:4,611,989...5,005,633
Ensembl chr10:4,611,593...5,005,614
JBrowse link
G Esr2 estrogen receptor 2 (beta) increases expression ISO tetramethrin results in increased expression of ESR2 protein CTD PMID:16326440 NCBI chr12:76,120,419...76,177,259
Ensembl chr12:76,120,419...76,177,259
JBrowse link
G Folh1 folate hydrolase 1 decreases expression ISO tetramethrin results in decreased expression of FOLH1 mRNA CTD PMID:12711008 NCBI chr 7:86,716,525...86,776,053
Ensembl chr 7:86,718,977...86,775,943
JBrowse link
G Igf1 insulin-like growth factor 1 multiple interactions EXP tetramethrin inhibits the reaction [IGF1 protein results in increased import of Calcium] CTD PMID:1550224 PMID:2460452 PMID:2539779 NCBI chr10:87,858,265...87,937,047
Ensembl chr10:87,858,265...87,937,042
JBrowse link
G Igf2 insulin-like growth factor 2 multiple interactions EXP tetramethrin inhibits the reaction [IGF2 protein results in increased import of Calcium] CTD PMID:2442157 PMID:2539779 NCBI chr 7:142,650,768...142,666,816
Ensembl chr 7:142,650,766...142,666,816
JBrowse link
G Kcnh2 potassium voltage-gated channel, subfamily H (eag-related), member 2 decreases activity ISO tetramethrin results in decreased activity of KCNH2 protein CTD PMID:28551711 NCBI chr 5:24,319,589...24,351,684
Ensembl chr 5:24,319,589...24,351,604
JBrowse link
G Nkx3-1 NK3 homeobox 1 decreases expression ISO tetramethrin results in decreased expression of NKX3-1 mRNA CTD PMID:12711008 NCBI chr14:69,190,692...69,194,658
Ensembl chr14:69,190,638...69,194,662
JBrowse link
G Nr1i2 nuclear receptor subfamily 1, group I, member 2 multiple interactions
increases activity
ISO CES2 protein inhibits the reaction [tetramethrin results in increased activity of NR1I2 protein] CTD PMID:19249324 NCBI chr16:38,248,349...38,294,849
Ensembl chr16:38,248,323...38,294,824
JBrowse link
G Nr3c1 nuclear receptor subfamily 3, group C, member 1 multiple interactions ISO [Diethylhexyl Phthalate co-treated with butylparaben co-treated with tetramethrin co-treated with propylparaben] results in increased activity of NR3C1 protein; [Diethylhexyl Phthalate co-treated with butylparaben co-treated with tetramethrin] results in increased activity of NR3C1 protein; [tetramethrin co-treated with propylparaben] results in increased activity of NR3C1 protein CTD PMID:25448277 NCBI chr18:39,410,545...39,519,421
Ensembl chr18:39,410,545...39,519,421
JBrowse link
G S100g S100 calcium binding protein G decreases expression
multiple interactions
ISO tetramethrin results in decreased expression of S100G mRNA
tetramethrin inhibits the reaction [Estradiol results in increased expression of S100G mRNA]
CTD PMID:16326440 NCBI chr  X:162,961,992...162,964,599
Ensembl chr  X:162,961,992...162,964,599
JBrowse link
G Shbg sex hormone binding globulin affects binding ISO tetramethrin binds to SHBG protein CTD PMID:32278787 NCBI chr11:69,610,282...69,618,026
Ensembl chr11:69,614,804...69,617,905
JBrowse link
G Tmprss2 transmembrane protease, serine 2 increases expression ISO tetramethrin results in increased expression of TMPRSS2 mRNA CTD PMID:12711008 NCBI chr16:97,564,682...97,659,541
Ensembl chr16:97,564,682...97,611,195
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 21720
    role 21698
      application 21205
        pesticide 16821
          insecticide 14096
            phthalimide insecticide 15
              tetramethrin + 15
Path 2
Term Annotations click to browse term
  CHEBI ontology 21720
    subatomic particle 21705
      composite particle 21705
        hadron 21705
          baryon 21705
            nucleon 21705
              atomic nucleus 21705
                atom 21705
                  main group element atom 21622
                    p-block element atom 21622
                      carbon group element atom 21427
                        carbon atom 21326
                          organic molecular entity 21326
                            organic molecule 21222
                              organic cyclic compound 20806
                                organic heterocyclic compound 19777
                                  organic heteropolycyclic compound 19370
                                    organic heterobicyclic compound 17740
                                      benzopyrrole 9502
                                        isoindoles 1195
                                          phthalimides 1060
                                            phthalimide insecticide 15
                                              tetramethrin + 15
paths to the root