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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:pyrethroid ether insecticide
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Accession:CHEBI:39351 term browser browse the term
Synonyms:related_synonym: pyrethroid ether insecticides


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etofenprox term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ar androgen receptor multiple interactions ISO Dihydrotestosterone inhibits the reaction [ethofenprox results in increased activity of AR protein] CTD PMID:15064155 NCBI chr  X:97,192,363...97,366,824
Ensembl chr  X:97,192,375...97,366,821 		JBrowse link
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 increases activity ISO ethofenprox results in increased activity of CYP1A1 protein CTD PMID:20009351 NCBI chr 9:57,595,211...57,611,107
Ensembl chr 9:57,595,211...57,611,107 		JBrowse link
G Cyp2b13 cytochrome P450, family 2, subfamily b, polypeptide 13 multiple interactions ISO [ethofenprox co-treated with Diethylnitrosamine] results in increased expression of CYP2B2 mRNA CTD PMID:22467020 NCBI chr 7:25,760,813...25,795,622
Ensembl chr 7:25,760,922...25,795,622 		JBrowse link
G Esr1 estrogen receptor 1 (alpha) decreases activity ISO ethofenprox results in decreased activity of ESR1 protein CTD PMID:20410157 NCBI chr10:4,561,989...4,955,633
Ensembl chr10:4,561,593...4,955,614 		JBrowse link
G Gsta1 glutathione S-transferase, alpha 1 (Ya) multiple interactions ISO [ethofenprox co-treated with Diethylnitrosamine] results in increased expression of GSTA5 mRNA CTD PMID:22467020 NCBI chr 9:78,137,951...78,149,965
Ensembl chr 9:78,137,938...78,149,966 		JBrowse link
G Nqo1 NAD(P)H dehydrogenase, quinone 1 multiple interactions ISO [ethofenprox co-treated with Diethylnitrosamine] results in increased expression of NQO1 mRNA CTD PMID:22467020 NCBI chr 8:108,114,856...108,139,012
Ensembl chr 8:108,114,857...108,129,838 		JBrowse link
G Nr1i2 nuclear receptor subfamily 1, group I, member 2 multiple interactions EXP
ISO		 ethofenprox binds to and results in increased activity of NR1I2 protein CTD PMID:21115097 NCBI chr16:38,068,711...38,115,211
Ensembl chr16:38,068,685...38,115,186 		JBrowse link
G Nr1i3 nuclear receptor subfamily 1, group I, member 3 multiple interactions
increases activity		 ISO [ethofenprox co-treated with Diethylnitrosamine] results in decreased expression of NR1I3 mRNA; ethofenprox affects the localization of and results in increased activity of NR1I3 protein
ethofenprox results in increased activity of NR1I3 protein		 CTD PMID:22467020 PMID:28927721 NCBI chr 1:171,041,503...171,046,414
Ensembl chr 1:171,041,539...171,048,270 		JBrowse link
G Sult2a1 sulfotransferase family 2A, dehydroepiandrosterone (DHEA)-preferring, member 1 multiple interactions ISO [ethofenprox co-treated with Diethylnitrosamine] results in decreased expression of SULT2A1 mRNA CTD PMID:22467020 NCBI chr 7:13,530,171...13,571,335
Ensembl chr 7:13,530,171...13,571,334 		JBrowse link
G Ugt1a6b UDP glucuronosyltransferase 1 family, polypeptide A6B multiple interactions ISO [ethofenprox co-treated with Diethylnitrosamine] results in increased expression of UGT1A6 mRNA CTD PMID:22467020 NCBI chr 1:88,030,979...88,146,720
Ensembl chr 1:88,030,974...88,146,725 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 22178
    role 22194
      application 21744
        pesticide 18859
          insecticide 17183
            pyrethroid insecticide 3364
              pyrethroid ether insecticide 10
                etofenprox 10
                flufenprox 0
                halfenprox 0
                silafluofen 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 22178
    role 22194
      biological role 22162
        biophysical role 14206
          membrane transport modulator 14020
            sodium channel modulator 6702
              pyrethroid insecticide 3364
                pyrethroid ether insecticide 10
                  etofenprox 10
                  flufenprox 0
                  halfenprox 0
                  silafluofen 0
paths to the root