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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:pyrethroid ether insecticide
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Accession:CHEBI:39351 term browser browse the term
Synonyms:related_synonym: pyrethroid ether insecticides


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etofenprox term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AKR7A3 aldo-keto reductase family 7 member A3 multiple interactions ISO [ethofenprox co-treated with Diethylnitrosamine] results in increased expression of AKR7A3 mRNA CTD PMID:22467020 NCBI chr 1:19,274,229...19,288,770
Ensembl chr 1:19,282,573...19,288,770 		JBrowse link
G AR androgen receptor multiple interactions EXP Dihydrotestosterone inhibits the reaction [ethofenprox results in increased activity of AR protein] CTD PMID:15064155 NCBI chr  X:67,544,021...67,730,619
Ensembl chr  X:67,544,021...67,730,619 		JBrowse link
G CYP1A1 cytochrome P450 family 1 subfamily A member 1 increases activity ISO ethofenprox results in increased activity of CYP1A1 protein CTD PMID:20009351 NCBI chr15:74,719,542...74,725,528
Ensembl chr15:74,719,542...74,725,536 		JBrowse link
G ESR1 estrogen receptor 1 decreases activity ISO ethofenprox results in decreased activity of ESR1 protein CTD PMID:20410157 NCBI chr 6:151,656,672...152,129,619
Ensembl chr 6:151,656,691...152,129,619 		JBrowse link
G GSTA5 glutathione S-transferase alpha 5 multiple interactions ISO [ethofenprox co-treated with Diethylnitrosamine] results in increased expression of GSTA5 mRNA CTD PMID:22467020 NCBI chr 6:52,831,692...52,846,245
Ensembl chr 6:52,831,655...52,840,843 		JBrowse link
G NQO1 NAD(P)H quinone dehydrogenase 1 multiple interactions ISO [ethofenprox co-treated with Diethylnitrosamine] results in increased expression of NQO1 mRNA CTD PMID:22467020 NCBI chr16:69,709,401...69,726,560
Ensembl chr16:69,706,996...69,726,668 		JBrowse link
G NR1I2 nuclear receptor subfamily 1 group I member 2 multiple interactions ISO
EXP		 ethofenprox binds to and results in increased activity of NR1I2 protein CTD PMID:21115097 NCBI chr 3:119,782,101...119,818,487
Ensembl chr 3:119,780,484...119,818,487 		JBrowse link
G NR1I3 nuclear receptor subfamily 1 group I member 3 multiple interactions
increases activity		 ISO
EXP		 [ethofenprox co-treated with Diethylnitrosamine] results in decreased expression of NR1I3 mRNA; ethofenprox affects the localization of and results in increased activity of NR1I3 protein
ethofenprox results in increased activity of NR1I3 protein		 CTD PMID:22467020 PMID:28927721 NCBI chr 1:161,229,669...161,238,203
Ensembl chr 1:161,229,666...161,238,244 		JBrowse link
G SULT2A1 sulfotransferase family 2A member 1 multiple interactions ISO [ethofenprox co-treated with Diethylnitrosamine] results in decreased expression of SULT2A1 mRNA CTD PMID:22467020 NCBI chr19:47,870,467...47,886,315
Ensembl chr19:47,870,467...47,886,315 		JBrowse link
G UGT1A6 UDP glucuronosyltransferase family 1 member A6 multiple interactions ISO [ethofenprox co-treated with Diethylnitrosamine] results in increased expression of UGT1A6 mRNA CTD PMID:22467020 NCBI chr 2:233,691,702...233,773,300
Ensembl chr 2:233,691,607...233,773,300 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 25408
    role 25341
      application 24571
        pesticide 19750
          insecticide 17513
            pyrethroid insecticide 2858
              pyrethroid ether insecticide 10
                etofenprox 10
                flufenprox 0
                halfenprox 0
                silafluofen 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 25408
    role 25341
      biological role 25304
        biophysical role 13904
          membrane transport modulator 13683
            sodium channel modulator 6526
              pyrethroid insecticide 2858
                pyrethroid ether insecticide 10
                  etofenprox 10
                  flufenprox 0
                  halfenprox 0
                  silafluofen 0
paths to the root