pyrethroid ether insecticide - Ontology Report - Rat Genome Database

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CHEBI ONTOLOGY - ANNOTATIONS

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The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:	pyrethroid ether insecticide	go back to main search page
Accession:	CHEBI:39351	browse the term
Synonyms:	related_synonym:	pyrethroid ether insecticides

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Rat (11) Mouse (10) Human (10) Chinchilla (0) Bonobo (0) Dog (0) Squirrel (0) Pig (0) Green Monkey (0) Naked Mole-rat (0) All
Genes (11)

etofenprox

term browser

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

G

aldo-keto reductase family 7 member A3

multiple interactions

[ethofenprox co-treated with Diethylnitrosamine] results in increased expression of AKR7A3 mRNA

NCBI chr 5:151,590,968...151,601,394
Ensembl chr 5:151,584,479...151,601,394

G

androgen receptor

multiple interactions

Dihydrotestosterone inhibits the reaction [ethofenprox results in increased activity of AR protein]

NCBI chr X:63,104,771...63,273,934
Ensembl chr X:63,104,771...63,273,925

G

cytochrome P450, family 1, subfamily a, polypeptide 1

increases activity

ethofenprox results in increased activity of CYP1A1 protein

NCBI chr 8:58,096,021...58,102,130
Ensembl chr 8:58,096,077...58,102,125

G

cytochrome P450, family 2, subfamily b, polypeptide 2

multiple interactions

[ethofenprox co-treated with Diethylnitrosamine] results in increased expression of CYP2B2 mRNA

NCBI chr 1:81,594,534...81,608,567
Ensembl chr 1:81,594,555...81,608,566

G

estrogen receptor 1

decreases activity

ethofenprox results in decreased activity of ESR1 protein

NCBI chr 1:41,106,335...41,499,104
Ensembl chr 1:41,210,475...41,495,002

G

glutathione S-transferase alpha 5

multiple interactions

[ethofenprox co-treated with Diethylnitrosamine] results in increased expression of GSTA5 mRNA

NCBI chr 8:79,105,561...79,117,472
Ensembl chr 8:79,105,661...79,117,472

G

NAD(P)H quinone dehydrogenase 1

multiple interactions

[ethofenprox co-treated with Diethylnitrosamine] results in increased expression of NQO1 mRNA

NCBI chr19:35,295,633...35,310,528
Ensembl chr19:35,295,573...35,310,557

G

nuclear receptor subfamily 1, group I, member 2

multiple interactions

ethofenprox binds to and results in increased activity of NR1I2 protein

NCBI chr11:62,460,213...62,496,665
Ensembl chr11:62,460,213...62,496,658

G

nuclear receptor subfamily 1, group I, member 3

multiple interactions
increases activity

[ethofenprox co-treated with Diethylnitrosamine] results in decreased expression of NR1I3 mRNA; ethofenprox affects the localization of and results in increased activity of NR1I3 protein
ethofenprox results in increased activity of NR1I3 protein

PMID:22467020 PMID:28927721

NCBI chr13:83,632,940...83,638,193
Ensembl chr13:83,632,899...83,637,906

G

sulfotransferase family 2A member 1

multiple interactions

[ethofenprox co-treated with Diethylnitrosamine] results in decreased expression of SULT2A1 mRNA

NCBI chr 1:75,451,178...75,508,142
Ensembl chr 1:74,911,100...75,508,134

G

UDP glucuronosyltransferase family 1 member A6

multiple interactions

[ethofenprox co-treated with Diethylnitrosamine] results in increased expression of UGT1A6 mRNA

NCBI chr 9:88,747,229...88,808,465
Ensembl chr 9:88,713,184...88,808,465

Term paths to the root

Path 1
Term	Annotations
CHEBI ontology	19818
role	19790
application	19622
pesticide	17446
insecticide	15675
pyrethroid insecticide	2970
pyrethroid ether insecticide	11
etofenprox	11
flufenprox	0
halfenprox	0
silafluofen	0
Path 2
Term	Annotations
CHEBI ontology	19818
role	19790
biological role	19788
biophysical role	13832
membrane transport modulator	13668
sodium channel modulator	6426
pyrethroid insecticide	2970
pyrethroid ether insecticide	11
etofenprox	11
flufenprox	0
halfenprox	0
silafluofen	0

paths to the root