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G |
Cyp1a2 |
cytochrome P450, family 1, subfamily a, polypeptide 2 |
affects binding |
ISO |
4-phenoxyphenol binds to CYP1A2 protein |
CTD |
PMID:32278787 |
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NCBI chr 8:58,075,367...58,082,255
Ensembl chr 8:58,075,367...58,082,312
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G |
Abcb1a |
ATP binding cassette subfamily B member 1A |
multiple interactions decreases activity |
ISO |
fenoxycarb inhibits the reaction [ABCB1 protein results in increased transport of calcein AM] fenoxycarb results in decreased activity of ABCB1 protein |
CTD |
PMID:21783720 |
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NCBI chr 4:25,357,467...25,529,941
Ensembl chr 4:25,158,362...25,442,709
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G |
Ache |
acetylcholinesterase |
decreases activity |
EXP |
fenoxycarb results in decreased activity of ACHE protein |
CTD |
PMID:14644616 |
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NCBI chr12:19,406,133...19,413,713
Ensembl chr12:19,407,360...19,413,651
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G |
Chrna3 |
cholinergic receptor nicotinic alpha 3 subunit |
multiple interactions |
EXP |
fenoxycarb results in decreased activity of [CHRNA3 protein binds to CHRNB2 protein]; fenoxycarb results in decreased activity of [CHRNA3 protein binds to CHRNB4 protein] |
CTD |
PMID:14644616 |
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NCBI chr 8:55,401,668...55,415,165
Ensembl chr 8:55,401,702...55,415,165
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G |
Chrna4 |
cholinergic receptor nicotinic alpha 4 subunit |
multiple interactions |
EXP |
fenoxycarb results in decreased activity of [CHRNA4 protein binds to CHRNB2 protein]; fenoxycarb results in decreased activity of [CHRNA4 protein binds to CHRNB4 protein] |
CTD |
PMID:14644616 |
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NCBI chr 3:168,136,246...168,157,839
Ensembl chr 3:168,136,266...168,156,957
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G |
Chrnb2 |
cholinergic receptor nicotinic beta 2 subunit |
multiple interactions |
EXP |
fenoxycarb results in decreased activity of [CHRNA3 protein binds to CHRNB2 protein]; fenoxycarb results in decreased activity of [CHRNA4 protein binds to CHRNB2 protein] |
CTD |
PMID:14644616 |
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NCBI chr 2:175,181,402...175,189,619
Ensembl chr 2:175,181,402...175,189,619
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G |
Chrnb4 |
cholinergic receptor nicotinic beta 4 subunit |
multiple interactions |
EXP |
fenoxycarb results in decreased activity of [CHRNA3 protein binds to CHRNB4 protein]; fenoxycarb results in decreased activity of [CHRNA4 protein binds to CHRNB4 protein] |
CTD |
PMID:14644616 |
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NCBI chr 8:55,417,583...55,437,027
Ensembl chr 8:55,418,313...55,437,027
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G |
Nr1i3 |
nuclear receptor subfamily 1, group I, member 3 |
increases activity |
ISO |
fenoxycarb results in increased activity of NR1I3 protein |
CTD |
PMID:28927721 |
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NCBI chr13:83,632,940...83,638,193
Ensembl chr13:83,632,899...83,637,906
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G |
Casp3 |
caspase 3 |
increases expression |
ISO |
pyriproxyfen metabolite results in increased expression of CASP3 protein |
CTD |
PMID:34289950 |
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NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648
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G |
Dlx2 |
distal-less homeobox 2 |
increases expression multiple interactions |
ISO |
pyriproxyfen metabolite results in increased expression of DLX2 mRNA [pyriproxyfen metabolite co-treated with Triiodothyronine] results in increased expression of DLX2 mRNA |
CTD |
PMID:34289950 |
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NCBI chr 3:56,370,238...56,373,581
Ensembl chr 3:56,370,483...56,373,597
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G |
Fasn |
fatty acid synthase |
increases expression multiple interactions |
ISO |
pyriproxyfen metabolite results in increased expression of FASN mRNA [pyriproxyfen metabolite co-treated with Triiodothyronine] results in increased expression of FASN mRNA |
CTD |
PMID:34289950 |
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NCBI chr10:106,072,093...106,090,259
Ensembl chr10:106,072,091...106,090,261
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G |
Msi1 |
musashi RNA-binding protein 1 |
multiple interactions increases expression |
ISO |
[pyriproxyfen metabolite co-treated with Triiodothyronine] results in increased expression of MSI1 mRNA pyriproxyfen metabolite results in increased expression of MSI1 mRNA; pyriproxyfen metabolite results in increased expression of MSI1 protein |
CTD |
PMID:34289950 |
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NCBI chr12:41,158,301...41,251,134
Ensembl chr12:41,158,599...41,191,076
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G |
Nr1i3 |
nuclear receptor subfamily 1, group I, member 3 |
increases activity |
ISO |
pyriproxyfen results in increased activity of NR1I3 protein |
CTD |
PMID:28927721 |
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NCBI chr13:83,632,940...83,638,193
Ensembl chr13:83,632,899...83,637,906
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G |
Sox10 |
SRY-box transcription factor 10 |
decreases expression multiple interactions |
ISO |
pyriproxyfen metabolite results in decreased expression of SOX10 mRNA [pyriproxyfen metabolite co-treated with Triiodothyronine] results in decreased expression of SOX10 mRNA |
CTD |
PMID:34289950 |
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NCBI chr 7:110,725,274...110,734,651
Ensembl chr 7:110,725,274...110,735,544
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