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G |
Abcb1a |
ATP binding cassette subfamily B member 1A |
multiple interactions increases expression decreases response to substance decreases expression decreases activity |
ISO EXP |
abamectin inhibits the reaction [ABCB1 protein results in increased transport of bisbenzimide ethoxide trihydrochloride] abamectin results in increased expression of ABCB1A mRNA [Ascorbic Acid co-treated with Sesame Oil] inhibits the reaction [abamectin results in increased expression of ABCB1A mRNA]; Ascorbic Acid inhibits the reaction [abamectin results in increased expression of ABCB1A mRNA]; Sesame Oil inhibits the reaction [abamectin results in increased expression of ABCB1A mRNA] ABCB1A protein results in decreased susceptibility to abamectin abamectin results in decreased expression of ABCB1A protein abamectin results in decreased activity of ABCB1A protein abamectin inhibits the reaction [ABCB1A protein results in increased transport of bisbenzimide ethoxide trihydrochloride] abamectin results in decreased activity of ABCB1 protein |
CTD |
PMID:9144452 PMID:17134887 PMID:19879343 PMID:25865432 PMID:31739238 |
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NCBI chr 4:22,339,829...22,517,642
Ensembl chr 4:22,133,521...22,425,515
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G |
Abcc1 |
ATP binding cassette subfamily C member 1 |
multiple interactions decreases activity |
ISO |
abamectin inhibits the reaction [ABCC1 protein results in increased transport of bisbenzimide ethoxide trihydrochloride] abamectin results in decreased activity of ABCC1 protein |
CTD |
PMID:25865432 |
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NCBI chr10:549,537...672,235
Ensembl chr10:549,883...672,196
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G |
Actb |
actin, beta |
decreases expression |
ISO |
abamectin results in decreased expression of ACTB protein |
CTD |
PMID:19879343 |
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NCBI chr12:13,715,843...13,718,813
Ensembl chr12:13,715,843...13,718,841
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G |
Akt1 |
AKT serine/threonine kinase 1 |
decreases expression |
ISO |
abamectin results in decreased expression of AKT1 protein |
CTD |
PMID:30958899 |
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NCBI chr 6:137,218,398...137,239,970
Ensembl chr 6:137,218,376...137,236,258
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G |
Casp3 |
caspase 3 |
increases activity increases expression multiple interactions |
ISO EXP |
abamectin results in increased activity of CASP3 protein abamectin results in increased expression of CASP3 protein [Ascorbic Acid co-treated with Sesame Oil] inhibits the reaction [abamectin results in increased expression of CASP3 protein]; Ascorbic Acid inhibits the reaction [abamectin results in increased expression of CASP3 protein]; Sesame Oil inhibits the reaction [abamectin results in increased expression of CASP3 protein] |
CTD |
PMID:30958899 PMID:31739238 |
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NCBI chr16:48,845,011...48,863,249
Ensembl chr16:48,845,012...48,863,204
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G |
Cat |
catalase |
multiple interactions increases activity |
EXP |
[Ascorbic Acid co-treated with Sesame Oil] inhibits the reaction [abamectin results in increased activity of CAT protein]; Ascorbic Acid inhibits the reaction [abamectin results in increased activity of CAT protein]; Sesame Oil inhibits the reaction [abamectin results in increased activity of CAT protein] |
CTD |
PMID:31739238 |
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NCBI chr 3:93,379,872...93,412,058
Ensembl chr 3:93,379,874...93,412,058
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G |
Cyp2e1 |
cytochrome P450, family 2, subfamily e, polypeptide 1 |
multiple interactions increases expression |
EXP |
[Ascorbic Acid co-treated with Sesame Oil] inhibits the reaction [abamectin results in increased expression of CYP2E1 protein]; Ascorbic Acid inhibits the reaction [abamectin results in increased expression of CYP2E1 protein]; Sesame Oil inhibits the reaction [abamectin results in increased expression of CYP2E1 protein] |
CTD |
PMID:31739238 |
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NCBI chr 1:213,511,892...213,522,195
Ensembl chr 1:213,511,874...213,535,542
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G |
Nr1h4 |
nuclear receptor subfamily 1, group H, member 4 |
multiple interactions |
ISO |
abamectin inhibits the reaction [Chenodeoxycholic Acid results in increased activity of NR1H4 protein]; abamectin inhibits the reaction [pregna-4,17-diene-3,16-dione results in decreased activity of NR1H4 protein] |
CTD |
PMID:25257666 |
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NCBI chr 7:30,003,429...30,162,095
Ensembl chr 7:30,003,429...30,162,056
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G |
Sqstm1 |
sequestosome 1 |
decreases expression |
ISO |
abamectin results in decreased expression of SQSTM1 protein |
CTD |
PMID:30958899 |
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NCBI chr10:35,704,728...35,716,316
Ensembl chr10:35,704,730...35,716,294
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G |
Tnf |
tumor necrosis factor |
increases expression multiple interactions |
EXP |
abamectin results in increased expression of TNF protein [Ascorbic Acid co-treated with Sesame Oil] inhibits the reaction [abamectin results in increased expression of TNF protein]; Ascorbic Acid inhibits the reaction [abamectin results in increased expression of TNF protein]; Sesame Oil inhibits the reaction [abamectin results in increased expression of TNF protein] |
CTD |
PMID:31739238 |
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NCBI chr20:5,189,382...5,192,000
Ensembl chr20:5,189,390...5,192,000
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G |
Tubb3 |
tubulin, beta 3 class III |
decreases expression |
ISO |
abamectin results in decreased expression of TUBB3 protein |
CTD |
PMID:19879343 |
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NCBI chr19:56,220,759...56,229,813
Ensembl chr19:56,220,755...56,229,813
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G |
Abcb1a |
ATP binding cassette subfamily B member 1A |
decreases activity multiple interactions |
ISO |
emamectin results in decreased activity of ABCB1 protein emamectin inhibits the reaction [ABCB1 protein results in increased transport of bisbenzimide ethoxide trihydrochloride] emamectin results in decreased activity of ABCB1A protein emamectin inhibits the reaction [ABCB1A protein results in increased transport of bisbenzimide ethoxide trihydrochloride] |
CTD |
PMID:25865432 |
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NCBI chr 4:22,339,829...22,517,642
Ensembl chr 4:22,133,521...22,425,515
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G |
Abcc1 |
ATP binding cassette subfamily C member 1 |
multiple interactions decreases activity |
ISO |
emamectin inhibits the reaction [ABCC1 protein results in increased transport of bisbenzimide ethoxide trihydrochloride] emamectin results in decreased activity of ABCC1 protein |
CTD |
PMID:25865432 |
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NCBI chr10:549,537...672,235
Ensembl chr10:549,883...672,196
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G |
Ncoa2 |
nuclear receptor coactivator 2 |
multiple interactions |
ISO |
emamectin inhibits the reaction [Chenodeoxycholic Acid promotes the reaction [NCOA2 protein modified form binds to NR1H4 protein]] |
CTD |
PMID:27773686 |
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NCBI chr 5:5,466,544...5,696,540
Ensembl chr 5:5,616,483...5,694,598
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G |
Nr1h4 |
nuclear receptor subfamily 1, group H, member 4 |
multiple interactions |
ISO |
emamectin inhibits the reaction [Chenodeoxycholic Acid promotes the reaction [NCOA2 protein modified form binds to NR1H4 protein]]; emamectin inhibits the reaction [Chenodeoxycholic Acid results in increased activity of NR1H4 protein]; emamectin inhibits the reaction [pregna-4,17-diene-3,16-dione results in decreased activity of NR1H4 protein] |
CTD |
PMID:25257666 PMID:27773686 |
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NCBI chr 7:30,003,429...30,162,095
Ensembl chr 7:30,003,429...30,162,056
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G |
Cat |
catalase |
multiple interactions decreases activity |
ISO |
Plant Oils inhibits the reaction [emamectin benzoate results in decreased activity of CAT protein] |
CTD |
PMID:29268245 |
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NCBI chr 3:93,379,872...93,412,058
Ensembl chr 3:93,379,874...93,412,058
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G |
Cyp2e1 |
cytochrome P450, family 2, subfamily e, polypeptide 1 |
multiple interactions increases expression |
ISO |
Plant Oils inhibits the reaction [emamectin benzoate results in increased expression of CYP2E1 mRNA] |
CTD |
PMID:29268245 |
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NCBI chr 1:213,511,892...213,522,195
Ensembl chr 1:213,511,874...213,535,542
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G |
Dio1 |
iodothyronine deiodinase 1 |
decreases activity |
ISO |
emamectin benzoate results in decreased activity of DIO1 protein |
CTD |
PMID:29228274 |
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NCBI chr 5:126,894,837...126,911,532
Ensembl chr 5:126,895,286...126,911,520
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G |
Mgst1 |
microsomal glutathione S-transferase 1 |
increases expression multiple interactions |
ISO |
emamectin benzoate results in increased expression of MGST1 mRNA Plant Oils inhibits the reaction [emamectin benzoate results in increased expression of MGST1 mRNA] |
CTD |
PMID:29268245 |
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NCBI chr 4:172,119,382...172,134,609
Ensembl chr 4:172,119,331...172,134,607
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G |
Nts |
neurotensin |
affects activity |
ISO |
emamectin benzoate affects the activity of NTS protein |
CTD |
PMID:23611293 |
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NCBI chr 7:44,111,594...44,120,998
Ensembl chr 7:44,111,151...44,121,130
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