Send us a Message



Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   

CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:organosulfur pesticide
go back to main search page
Accession:CHEBI:39189 term browser browse the term



show annotations for term's descendants           Sort by:
 
disulfiram term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G 2010315B03Rik RIKEN cDNA 2010315B03 gene multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of ZNF77 mRNA CTD PMID:24690739 NCBI chr 9:124,291,802...124,312,719
Ensembl chr 9:124,291,804...124,312,696
JBrowse link
G Aars alanyl-tRNA synthetase multiple interactions ISO [Disulfiram binds to Copper] which results in increased expression of AARS1 mRNA CTD PMID:24690739 NCBI chr 8:111,027,778...111,055,569
Ensembl chr 8:111,033,144...111,057,664
JBrowse link
G Abat 4-aminobutyrate aminotransferase multiple interactions ISO [Ethanol co-treated with Disulfiram] results in decreased activity of ABAT protein; [Ethanol co-treated with Disulfiram] results in decreased expression of ABAT mRNA CTD PMID:9591243 NCBI chr16:8,513,429...8,621,568
Ensembl chr16:8,513,429...8,621,568
JBrowse link
G Abca1 ATP-binding cassette, sub-family A (ABC1), member 1 multiple interactions ISO [Disulfiram binds to Copper] which results in increased expression of ABCA1 mRNA CTD PMID:24690739 NCBI chr 4:53,030,789...53,159,988
Ensembl chr 4:53,030,787...53,159,895
JBrowse link
G Abca3 ATP-binding cassette, sub-family A (ABC1), member 3 multiple interactions ISO [Disulfiram binds to Copper] which results in increased expression of ABCA3 mRNA CTD PMID:24690739 NCBI chr17:24,351,921...24,410,204
Ensembl chr17:24,351,950...24,410,201
JBrowse link
G Abcb11 ATP-binding cassette, sub-family B (MDR/TAP), member 11 decreases activity
multiple interactions
ISO Disulfiram results in decreased activity of ABCB11 protein
Disulfiram inhibits the reaction [ABCB11 protein results in increased transport of Taurocholic Acid]
CTD PMID:24014644 NCBI chr 2:69,238,282...69,342,616
Ensembl chr 2:69,238,282...69,342,616
JBrowse link
G Abcb1a ATP-binding cassette, sub-family B (MDR/TAP), member 1A multiple interactions
decreases activity
ISO Disulfiram affects the reaction [ABCB1 protein results in increased hydrolysis of Adenosine Triphosphate]; Disulfiram inhibits the reaction [8-azidoadenosine 5'-triphosphate binds to ABCB1 protein]; Disulfiram inhibits the reaction [azidopine binds to ABCB1 protein]; Disulfiram inhibits the reaction [azidoprazosin binds to ABCB1 protein]
Disulfiram metabolite results in decreased activity of ABCB1 protein; Disulfiram results in decreased activity of ABCB1 protein
CTD PMID:10841824 PMID:14978246 PMID:16028354 NCBI chr 5:8,567,091...8,748,575
Ensembl chr 5:8,660,077...8,748,575
JBrowse link
G Abcc1 ATP-binding cassette, sub-family C (CFTR/MRP), member 1 decreases activity
multiple interactions
ISO Disulfiram results in decreased activity of ABCC1 protein
Disulfiram affects the reaction [ABCC1 protein results in increased hydrolysis of Adenosine Triphosphate]; Disulfiram inhibits the reaction [8-azidoadenosine 5'-triphosphate binds to ABCC1 protein]
CTD PMID:14978246 NCBI chr16:14,361,453...14,474,878
Ensembl chr16:14,361,558...14,475,737
JBrowse link
G Abcc4 ATP-binding cassette, sub-family C (CFTR/MRP), member 4 multiple interactions ISO Disulfiram inhibits the reaction [8-azidoadenosine 5'-triphosphate binds to ABCC4 protein]; Disulfiram inhibits the reaction [ABCC4 protein results in increased hydrolysis of Adenosine Triphosphate] CTD PMID:14978246 NCBI chr14:118,482,692...118,707,856
Ensembl chr14:118,482,692...118,706,219
JBrowse link
G Abcg1 ATP binding cassette subfamily G member 1 multiple interactions ISO [Disulfiram binds to Copper] which results in increased expression of ABCG1 mRNA CTD PMID:24690739 NCBI chr17:31,057,694...31,117,984
Ensembl chr17:31,057,675...31,117,988
JBrowse link
G Acad11 acyl-Coenzyme A dehydrogenase family, member 11 multiple interactions ISO [Disulfiram binds to Copper] which results in increased expression of ACAD11 mRNA CTD PMID:24690739 NCBI chr 9:104,063,724...104,127,656
Ensembl chr 9:104,063,377...104,127,725
JBrowse link
G Ace2 angiotensin I converting enzyme (peptidyl-dipeptidase A) 2 decreases expression ISO Disulfiram results in decreased expression of ACE2 mRNA CTD PMID:32808185 NCBI chr  X:164,139,342...164,188,418
Ensembl chr  X:164,139,332...164,188,420
JBrowse link
G Ache acetylcholinesterase decreases expression ISO Disulfiram results in decreased expression of ACHE protein CTD PMID:3868355 NCBI chr 5:137,288,247...137,294,466
Ensembl chr 5:137,287,519...137,294,466
JBrowse link
G Acss2 acyl-CoA synthetase short-chain family member 2 multiple interactions ISO [Disulfiram binds to Copper] which results in increased expression of ACSS2 mRNA CTD PMID:24690739 NCBI chr 2:155,518,043...155,562,743
Ensembl chr 2:155,517,948...155,585,724
JBrowse link
G Acta2 actin alpha 2, smooth muscle, aorta multiple interactions ISO [Disulfiram binds to Copper] which results in increased expression of ACTA2 mRNA CTD PMID:24690739 NCBI chr19:34,240,336...34,255,585
Ensembl chr19:34,241,090...34,255,590
JBrowse link
G Adam9 a disintegrin and metallopeptidase domain 9 (meltrin gamma) multiple interactions ISO [Disulfiram binds to Copper] which results in increased expression of ADAM9 mRNA CTD PMID:24690739 NCBI chr 8:24,949,611...25,017,040
Ensembl chr 8:24,949,611...25,016,927
JBrowse link
G Adamts1 a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 1 multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of ADAMTS1 mRNA CTD PMID:24690739 NCBI chr16:85,793,827...85,803,113
Ensembl chr16:85,793,827...85,803,113
JBrowse link
G Adarb1 adenosine deaminase, RNA-specific, B1 multiple interactions ISO [Disulfiram binds to Copper] which results in increased expression of ADARB1 mRNA CTD PMID:24690739 NCBI chr10:77,290,727...77,418,292
Ensembl chr10:77,290,726...77,418,270
JBrowse link
G Adcy3 adenylate cyclase 3 multiple interactions ISO [Disulfiram binds to Copper] which results in increased expression of ADCY3 mRNA CTD PMID:24690739 NCBI chr12:4,133,116...4,213,525
Ensembl chr12:4,133,103...4,213,525
JBrowse link
G Adgre5 adhesion G protein-coupled receptor E5 multiple interactions ISO [Disulfiram binds to Copper] which results in increased expression of ADGRE5 mRNA CTD PMID:24690739 NCBI chr 8:83,723,245...83,741,311
Ensembl chr 8:83,723,251...83,741,326
JBrowse link
G Adh1 alcohol dehydrogenase 1 (class I) decreases activity ISO Disulfiram results in decreased activity of ADH1 protein CTD PMID:15551062 NCBI chr 3:138,277,585...138,290,698
Ensembl chr 3:138,260,991...138,290,698
JBrowse link
G Adm adrenomedullin multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of ADM mRNA CTD PMID:24690739 NCBI chr 7:110,627,657...110,629,820
Ensembl chr 7:110,627,661...110,629,820
JBrowse link
G Afap1 actin filament associated protein 1 multiple interactions ISO [Disulfiram binds to Copper] which results in increased expression of AFAP1 mRNA CTD PMID:24690739 NCBI chr 5:35,893,319...36,003,923
Ensembl chr 5:35,893,319...36,003,923
JBrowse link
G Agxt alanine-glyoxylate aminotransferase multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of AGXT mRNA CTD PMID:24690739 NCBI chr 1:93,135,240...93,145,421
Ensembl chr 1:93,135,240...93,145,421
JBrowse link
G Agxt2 alanine-glyoxylate aminotransferase 2 multiple interactions ISO [Ethanol co-treated with Disulfiram] results in decreased activity of AGXT2 protein CTD PMID:9591243 NCBI chr15:10,358,516...10,410,158
Ensembl chr15:10,358,532...10,410,153
JBrowse link
G Ahsa1 AHA1, activator of heat shock protein ATPase 1 multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of AHSA1 mRNA CTD PMID:24690739 NCBI chr12:87,266,415...87,273,998
Ensembl chr12:87,266,479...87,273,998
JBrowse link
G AI597479 expressed sequence AI597479 multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of C2ORF49 mRNA CTD PMID:24690739 NCBI chr 1:43,098,710...43,115,946
Ensembl chr 1:43,098,710...43,115,947
JBrowse link
G Akr1b10 aldo-keto reductase family 1, member B10 (aldose reductase) increases expression ISO Disulfiram results in increased expression of AKR1B10 mRNA CTD PMID:20566472 NCBI chr 6:34,384,247...34,396,949
Ensembl chr 6:34,384,218...34,396,950
JBrowse link
G Akr1b3 aldo-keto reductase family 1, member B3 (aldose reductase) increases expression ISO Disulfiram results in increased expression of AKR1B1 mRNA CTD PMID:20566472 NCBI chr 6:34,303,930...34,317,489
Ensembl chr 6:34,302,434...34,317,478
JBrowse link
G Akr1c18 aldo-keto reductase family 1, member C18 increases expression ISO Disulfiram results in increased expression of AKR1C3 mRNA CTD PMID:20566472 NCBI chr13:4,132,615...4,150,646
Ensembl chr13:4,132,615...4,150,654
JBrowse link
G Alad aminolevulinate, delta-, dehydratase multiple interactions ISO [Disulfiram co-treated with Lead] results in decreased activity of ALAD protein CTD PMID:2748540 NCBI chr 4:62,505,984...62,520,063
Ensembl chr 4:62,509,169...62,519,918
JBrowse link
G Aldh1a1 aldehyde dehydrogenase family 1, subfamily A1 decreases activity
decreases expression
multiple interactions
ISO Disulfiram results in decreased activity of ALDH1A1 protein
Disulfiram results in decreased expression of ALDH1A1 mRNA; Disulfiram results in decreased expression of ALDH1A1 protein
Disulfiram inhibits the reaction [ALDH1A1 protein results in decreased susceptibility to maphosphamide]
CTD PMID:8562935 PMID:10998257 PMID:21035945 PMID:34242567 NCBI chr19:20,492,583...20,643,463
Ensembl chr19:20,492,715...20,643,465
JBrowse link
G Aldh1a2 aldehyde dehydrogenase family 1, subfamily A2 decreases activity ISO Disulfiram results in decreased activity of ALDH1A2 protein CTD PMID:22079344 NCBI chr 9:71,215,789...71,296,243
Ensembl chr 9:71,215,789...71,296,243
JBrowse link
G Aldh2 aldehyde dehydrogenase 2, mitochondrial decreases activity
decreases expression
multiple interactions
EXP
ISO
Disulfiram metabolite results in decreased activity of ALDH2 protein; Disulfiram results in decreased activity of ALDH2 protein
Disulfiram results in decreased expression of ALDH2 mRNA
[Disulfiram results in decreased activity of ALDH2 protein] which results in increased susceptibility to Glyceraldehyde; [Disulfiram results in decreased activity of ALDH2 protein] which results in increased susceptibility to glycolaldehyde; [Disulfiram results in decreased activity of ALDH2 protein] which results in increased susceptibility to Glyoxal; [Disulfiram results in decreased activity of ALDH2 protein] which results in increased susceptibility to hydroxypyruvic acid; [Disulfiram results in decreased activity of ALDH2 protein] which results in increased susceptibility to Pyruvaldehyde
CTD PMID:9585485 PMID:10513990 PMID:11142365 PMID:21334317 PMID:21376711 More... NCBI chr 5:121,566,027...121,593,824
Ensembl chr 5:121,566,027...121,593,824
JBrowse link
G Aldh3a1 aldehyde dehydrogenase family 3, subfamily A1 increases metabolic processing ISO ALDH3A1 protein results in increased metabolism of Disulfiram CTD PMID:18591790 NCBI chr11:61,208,510...61,218,418
Ensembl chr11:61,207,537...61,218,421
JBrowse link
G Angptl4 angiopoietin-like 4 multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of ANGPTL4 mRNA CTD PMID:24690739 NCBI chr17:33,774,900...33,781,575
Ensembl chr17:33,773,750...33,781,830
JBrowse link
G Ano6 anoctamin 6 multiple interactions ISO [Disulfiram binds to Copper] which results in increased expression of ANO6 mRNA CTD PMID:24690739 NCBI chr15:95,790,843...95,975,472
Ensembl chr15:95,790,843...95,974,751
JBrowse link
G Apbb3 amyloid beta (A4) precursor protein-binding, family B, member 3 multiple interactions ISO [Disulfiram binds to Copper] which results in increased expression of APBB3 mRNA CTD PMID:24690739 NCBI chr18:36,671,154...36,679,366
Ensembl chr18:36,671,154...36,679,366
JBrowse link
G App amyloid beta (A4) precursor protein multiple interactions ISO [Disulfiram binds to Copper] which results in increased expression of APP mRNA CTD PMID:24690739 NCBI chr16:84,952,666...85,175,255
Ensembl chr16:84,949,685...85,173,766
JBrowse link
G Ar androgen receptor multiple interactions ISO [Disulfiram co-treated with cupric chloride] results in decreased expression of AR protein; Disulfiram inhibits the reaction [[6-fluorotestosterone co-treated with Norgestrel] binds to and results in increased activity of AR protein] CTD PMID:19789329 PMID:33049310 NCBI chr  X:98,148,757...98,323,218
Ensembl chr  X:98,148,769...98,323,215
JBrowse link
G Arc activity regulated cytoskeletal-associated protein multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of ARC mRNA CTD PMID:24690739 NCBI chr15:74,669,081...74,672,570
Ensembl chr15:74,669,083...74,672,570
JBrowse link
G Asgr1 asialoglycoprotein receptor 1 multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of ASGR1 mRNA CTD PMID:24690739 NCBI chr11:70,048,909...70,057,895
Ensembl chr11:70,054,085...70,057,894
JBrowse link
G Asns asparagine synthetase multiple interactions ISO [Disulfiram binds to Copper] which results in increased expression of ASNS mRNA CTD PMID:24690739 NCBI chr 6:7,675,165...7,693,209
Ensembl chr 6:7,675,169...7,693,254
JBrowse link
G Atf1 activating transcription factor 1 multiple interactions ISO [Disulfiram co-treated with Copper] results in decreased activity of ATF1 protein; Copper promotes the reaction [Disulfiram results in decreased activity of ATF1 protein] CTD PMID:15367699 NCBI chr15:100,227,859...100,261,248
Ensembl chr15:100,227,819...100,261,244
JBrowse link
G Atf2 activating transcription factor 2 multiple interactions ISO [Disulfiram co-treated with Copper] results in decreased activity of ATF2 protein; Copper promotes the reaction [Disulfiram results in decreased activity of ATF2 protein] CTD PMID:15367699 NCBI chr 2:73,816,509...73,892,677
Ensembl chr 2:73,816,509...73,892,639
JBrowse link
G Atf3 activating transcription factor 3 multiple interactions
increases expression
ISO [Disulfiram binds to Copper] which results in decreased expression of ATF3 mRNA; MTF1 protein affects the reaction [Disulfiram results in increased expression of ATF3 mRNA] CTD PMID:24690739 PMID:32661532 NCBI chr 1:191,170,296...191,183,333
Ensembl chr 1:191,170,296...191,218,039
JBrowse link
G Atg101 autophagy related 101 multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of ATG101 mRNA CTD PMID:24690739 NCBI chr15:101,284,301...101,290,947
Ensembl chr15:101,284,272...101,290,945
JBrowse link
G Atp2b1 ATPase, Ca++ transporting, plasma membrane 1 decreases expression ISO Disulfiram results in decreased expression of ATP2B1 mRNA CTD PMID:15003327 NCBI chr10:98,914,630...99,026,143
Ensembl chr10:98,914,406...99,026,143
JBrowse link
G Atp5md ATP synthase membrane subunit DAPIT multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of ATP5MK mRNA CTD PMID:24690739 NCBI chr19:47,083,471...47,090,647
Ensembl chr19:47,083,464...47,090,647
JBrowse link
G Atp6v0d1 ATPase, H+ transporting, lysosomal V0 subunit D1 multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of ATP6V0D1 mRNA CTD PMID:24690739 NCBI chr 8:105,524,461...105,566,064
Ensembl chr 8:105,524,465...105,566,047
JBrowse link
G Atp6v1g1 ATPase, H+ transporting, lysosomal V1 subunit G1 multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of ATP6V1G1 mRNA CTD PMID:24690739 NCBI chr 4:63,544,765...63,550,701
Ensembl chr 4:63,544,772...63,550,750
JBrowse link
G Atxn1l ataxin 1-like multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of ATXN1L mRNA CTD PMID:24690739 NCBI chr 8:109,726,451...109,737,794
Ensembl chr 8:109,726,451...109,737,739
JBrowse link
G Atxn3 ataxin 3 affects localization
increases response to substance
ISO Disulfiram affects the localization of ATXN3 protein alternative form
ATXN3 protein alternative form results in increased susceptibility to Disulfiram
CTD PMID:31378764 NCBI chr12:101,918,901...101,959,121
Ensembl chr12:101,918,901...101,958,246
JBrowse link
G Bag3 BCL2-associated athanogene 3 multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of BAG3 mRNA CTD PMID:24690739 NCBI chr 7:128,523,583...128,546,981
Ensembl chr 7:128,523,616...128,546,981
JBrowse link
G Bak1 BCL2-antagonist/killer 1 multiple interactions ISO [arsenic trioxide co-treated with Ascorbic Acid co-treated with Disulfiram] results in decreased expression of BAK1 protein CTD PMID:24126434 NCBI chr17:27,019,812...27,028,627
Ensembl chr17:27,019,810...27,029,009
JBrowse link
G Bax BCL2-associated X protein increases expression
multiple interactions
ISO Disulfiram results in increased expression of BAX protein
[arsenic trioxide co-treated with Ascorbic Acid co-treated with Disulfiram] results in increased expression of BAX protein; [Copper co-treated with Disulfiram] results in increased expression of BAX protein
CTD PMID:17079463 PMID:23033007 PMID:24126434 NCBI chr 7:45,461,695...45,466,903
Ensembl chr 7:45,461,697...45,466,898
JBrowse link
G Bbs2 Bardet-Biedl syndrome 2 (human) multiple interactions ISO [Disulfiram binds to Copper] which results in increased expression of BBS2 mRNA CTD PMID:24690739 NCBI chr 8:94,067,952...94,099,369
Ensembl chr 8:94,067,954...94,098,928
JBrowse link
G BC003965 cDNA sequence BC003965 multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of C16ORF91 mRNA CTD PMID:24690739 NCBI chr17:25,184,561...25,187,662
Ensembl chr17:25,184,554...25,187,662
JBrowse link
G BC016579 cDNA sequence, BC016579 multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of C3ORF52 mRNA CTD PMID:24690739 NCBI chr16:45,626,848...45,655,852
Ensembl chr16:45,626,848...45,654,068
JBrowse link
G Bccip BRCA2 and CDKN1A interacting protein multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of BCCIP mRNA CTD PMID:24690739 NCBI chr 7:133,709,333...133,721,145
Ensembl chr 7:133,709,333...133,721,145
JBrowse link
G Bcl2 B cell leukemia/lymphoma 2 multiple interactions ISO [arsenic trioxide co-treated with Ascorbic Acid co-treated with Disulfiram] results in decreased expression of BCL2 protein; [Copper co-treated with Disulfiram] results in decreased expression of BCL2 protein; [Disulfiram co-treated with cupric chloride] results in decreased expression of BCL2 protein CTD PMID:21911303 PMID:23033007 PMID:24126434 NCBI chr 1:106,538,176...106,714,290
Ensembl chr 1:106,538,178...106,714,274
JBrowse link
G Bdnf brain derived neurotrophic factor multiple interactions ISO [Disulfiram binds to Copper] which results in increased expression of BDNF mRNA CTD PMID:24690739 NCBI chr 2:109,674,700...109,727,043
Ensembl chr 2:109,674,700...109,727,007
JBrowse link
G Bglap bone gamma carboxyglutamate protein increases expression ISO Disulfiram results in increased expression of BGLAP mRNA CTD PMID:24496638 NCBI chr 3:88,383,495...88,384,466
Ensembl chr 3:88,383,501...88,384,464
JBrowse link
G Bmp7 bone morphogenetic protein 7 multiple interactions EXP Disulfiram inhibits the reaction [[FSHB protein co-treated with LHB protein co-treated with Testosterone] results in increased expression of BMP7 mRNA] CTD PMID:22285649 NCBI chr 2:172,868,012...172,940,321
Ensembl chr 2:172,868,012...172,940,321
JBrowse link
G Brf2 BRF2, RNA polymerase III transcription initiation factor 50kDa subunit multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of BRF2 mRNA CTD PMID:24690739 NCBI chr 8:27,123,339...27,128,715
Ensembl chr 8:27,123,364...27,128,680
JBrowse link
G Btk Bruton agammaglobulinemia tyrosine kinase multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of BTK mRNA CTD PMID:24690739 NCBI chr  X:134,542,334...134,583,628
Ensembl chr  X:134,542,336...134,583,570
JBrowse link
G C1rb complement component 1, r subcomponent B multiple interactions ISO [Disulfiram binds to Copper] which results in increased expression of C1R mRNA CTD PMID:24690739 NCBI chr 6:124,570,430...124,581,044
Ensembl chr 6:124,570,294...124,581,171
JBrowse link
G C1s1 complement component 1, s subcomponent 1 multiple interactions ISO [Disulfiram binds to Copper] which results in increased expression of C1S mRNA CTD PMID:24690739 NCBI chr 6:124,530,344...124,542,392
Ensembl chr 6:124,530,345...124,542,359
JBrowse link
G C87436 expressed sequence C87436 multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of C2ORF42 mRNA CTD PMID:24690739 NCBI chr 6:86,434,637...86,470,388
Ensembl chr 6:86,438,374...86,473,500
JBrowse link
G Cacybp calcyclin binding protein multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of CACYBP mRNA CTD PMID:24690739 NCBI chr 1:160,202,367...160,212,892
Ensembl chr 1:160,202,367...160,212,875
JBrowse link
G Calcb calcitonin-related polypeptide, beta multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of CALCB mRNA CTD PMID:24690739 NCBI chr 7:114,716,555...114,723,368
Ensembl chr 7:114,718,643...114,723,365
JBrowse link
G Cald1 caldesmon 1 multiple interactions ISO [Disulfiram binds to Copper] which results in increased expression of CALD1 mRNA CTD PMID:24690739 NCBI chr 6:34,598,495...34,775,469
Ensembl chr 6:34,598,500...34,775,473
JBrowse link
G Car2 carbonic anhydrase 2 multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of CA2 mRNA CTD PMID:24690739 NCBI chr 3:14,886,269...14,900,770
Ensembl chr 3:14,886,273...14,900,770
JBrowse link
G Car7 carbonic anhydrase 7 multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of CA7 mRNA CTD PMID:24690739 NCBI chr 8:104,534,694...104,550,347
Ensembl chr 8:104,534,689...104,550,343
JBrowse link
G Casp3 caspase 3 multiple interactions
increases activity
ISO
EXP
[Disulfiram binds to cupric chloride] which results in increased activity of CASP3 protein; bathocuproine sulfonate inhibits the reaction [[Disulfiram binds to cupric chloride] which results in increased activity of CASP3 protein]
[Disulfiram binds to Copper] which results in increased activity of CASP3 protein; Disulfiram promotes the reaction [Carmustine results in increased cleavage of CASP3 protein]
Disulfiram results in increased activity of CASP3 protein
CTD PMID:11239917 PMID:17026967 PMID:17079463 PMID:24193513 PMID:24690739 NCBI chr 8:46,617,291...46,639,698
Ensembl chr 8:46,617,291...46,639,689
JBrowse link
G Casp7 caspase 7 increases activity ISO Disulfiram results in increased activity of CASP7 protein CTD PMID:17026967 NCBI chr19:56,396,833...56,442,348
Ensembl chr19:56,397,129...56,442,344
JBrowse link
G Casp9 caspase 9 multiple interactions ISO [Disulfiram binds to Copper] which results in increased activity of CASP9 protein CTD PMID:24690739 NCBI chr 4:141,793,612...141,815,978
Ensembl chr 4:141,793,612...141,815,976
JBrowse link
G Cat catalase increases expression
multiple interactions
decreases expression
ISO Disulfiram results in increased expression of CAT mRNA
Zinc Sulfate inhibits the reaction [Disulfiram results in decreased expression of CAT mRNA]
CTD PMID:20566472 PMID:32712770 NCBI chr 2:103,453,904...103,485,153
Ensembl chr 2:103,453,849...103,485,160
JBrowse link
G Ccar1 cell division cycle and apoptosis regulator 1 multiple interactions EXP
ISO
[Disulfiram binds to Copper] which results in increased expression of CCAR1 protein CTD PMID:24690739 NCBI chr10:62,743,928...62,792,368
Ensembl chr10:62,743,928...62,792,286
JBrowse link
G Ccdc58 coiled-coil domain containing 58 multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of MIX23 mRNA CTD PMID:24690739 NCBI chr16:36,071,660...36,092,118
Ensembl chr16:36,071,685...36,092,120
JBrowse link
G Ccdc59 coiled-coil domain containing 59 multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of CCDC59 mRNA CTD PMID:24690739 NCBI chr10:105,841,479...105,847,510
Ensembl chr10:105,841,067...105,847,833
JBrowse link
G Ccdc92 coiled-coil domain containing 92 multiple interactions ISO [Disulfiram binds to Copper] which results in increased expression of CCDC92 mRNA CTD PMID:24690739 NCBI chr 5:124,834,432...124,862,499
Ensembl chr 5:124,834,418...124,862,424
JBrowse link
G Cck cholecystokinin decreases expression
multiple interactions
ISO Disulfiram results in decreased expression of CCK protein alternative form
[Disulfiram binds to Copper] which results in decreased expression of CCK mRNA
CTD PMID:8246921 PMID:24690739 NCBI chr 9:121,489,824...121,495,694
Ensembl chr 9:121,489,824...121,495,694
JBrowse link
G Ccl2 chemokine (C-C motif) ligand 2 multiple interactions
decreases secretion
ISO [Disulfiram binds to Copper] which results in increased expression of CCL2 mRNA; [Zinc Sulfate co-treated with Disulfiram] inhibits the reaction [Lipopolysaccharides results in increased secretion of CCL2 protein]; Disulfiram inhibits the reaction [Lipopolysaccharides results in increased secretion of CCL2 protein]
Disulfiram results in decreased secretion of CCL2 protein
CTD PMID:24690739 PMID:32712770 NCBI chr11:82,035,577...82,037,452
Ensembl chr11:82,035,571...82,037,453
JBrowse link
G Ccl26 chemokine (C-C motif) ligand 26 multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of CCL26 mRNA CTD PMID:24690739 NCBI chr 5:135,560,448...135,563,569
Ensembl chr 5:135,560,448...135,563,569
JBrowse link
G Ccl5 chemokine (C-C motif) ligand 5 multiple interactions EXP
ISO
Disulfiram inhibits the reaction [[CCL5 protein binds to and results in increased activity of CCR5 protein] which results in increased abundance of Nitric Oxide]; Disulfiram inhibits the reaction [[CCL5 protein binds to and results in increased activity of CCR5 protein] which results in increased abundance of Reactive Oxygen Species]; Disulfiram inhibits the reaction [[CCL5 protein binds to and results in increased activity of CCR5 protein] which results in increased secretion of TNF protein]
[Disulfiram binds to Copper] which results in increased expression of CCL5 mRNA
CTD PMID:19016906 PMID:24690739 NCBI chr11:83,525,778...83,530,518
Ensembl chr11:83,525,778...83,530,518
JBrowse link
G Ccna2 cyclin A2 multiple interactions ISO [Disulfiram co-treated with Copper] results in decreased expression of CCNA2 protein CTD PMID:15367699 NCBI chr 3:36,564,865...36,573,038
Ensembl chr 3:36,564,865...36,572,150
JBrowse link
G Ccnd2 cyclin D2 multiple interactions EXP Disulfiram inhibits the reaction [[FSHB protein co-treated with LHB protein co-treated with Testosterone] results in increased expression of CCND2 mRNA] CTD PMID:22285649 NCBI chr 6:127,125,162...127,152,188
Ensembl chr 6:127,125,162...127,152,193
JBrowse link
G Ccnk cyclin K multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of CCNK mRNA CTD PMID:24690739 NCBI chr12:108,179,308...108,203,359
Ensembl chr12:108,179,579...108,203,359
JBrowse link
G Ccpg1 cell cycle progression 1 multiple interactions ISO [Disulfiram binds to Copper] which results in increased expression of CCPG1 mRNA CTD PMID:24690739 NCBI chr 9:72,985,402...73,016,340
Ensembl chr 9:72,985,429...73,016,340
JBrowse link
G Ccr2 chemokine (C-C motif) receptor 2 increases expression ISO Disulfiram results in increased expression of CCR2 protein CTD PMID:32712770 NCBI chr 9:124,101,918...124,109,140
Ensembl chr 9:124,101,950...124,113,557
JBrowse link
G Ccr5 chemokine (C-C motif) receptor 5 multiple interactions EXP Disulfiram inhibits the reaction [[CCL5 protein binds to and results in increased activity of CCR5 protein] which results in increased abundance of Nitric Oxide]; Disulfiram inhibits the reaction [[CCL5 protein binds to and results in increased activity of CCR5 protein] which results in increased abundance of Reactive Oxygen Species]; Disulfiram inhibits the reaction [[CCL5 protein binds to and results in increased activity of CCR5 protein] which results in increased secretion of TNF protein] CTD PMID:19016906 NCBI chr 9:124,121,543...124,127,183
Ensembl chr 9:124,121,543...124,147,699
JBrowse link
G Cd163 CD163 antigen decreases expression
multiple interactions
ISO Disulfiram results in decreased expression of CD163 mRNA
[Zinc Sulfate co-treated with Disulfiram] results in decreased expression of CD163 mRNA
CTD PMID:32712770 NCBI chr 6:124,304,636...124,330,529
Ensembl chr 6:124,304,656...124,330,527
JBrowse link
G Cd36 CD36 molecule multiple interactions
decreases expression
ISO [Zinc Sulfate co-treated with Disulfiram] results in decreased expression of CD36 mRNA
Disulfiram results in decreased expression of CD36 mRNA
CTD PMID:32712770 NCBI chr 5:17,781,690...17,888,959
Ensembl chr 5:17,781,690...17,888,801
JBrowse link
G Cd46 CD46 antigen, complement regulatory protein multiple interactions ISO [Disulfiram binds to Copper] which results in increased expression of CD46 mRNA CTD PMID:24690739 NCBI chr 1:195,038,971...195,098,784
Ensembl chr 1:195,036,826...195,092,249
JBrowse link
G Cd47 CD47 antigen (Rh-related antigen, integrin-associated signal transducer) multiple interactions ISO [Disulfiram binds to Copper] which results in increased expression of CD47 mRNA CTD PMID:24690739 NCBI chr16:49,851,328...49,912,503
Ensembl chr16:49,800,533...49,915,010
JBrowse link
G Cd9 CD9 antigen multiple interactions ISO [Disulfiram binds to Copper] which results in increased expression of CD9 mRNA CTD PMID:24690739 NCBI chr 6:125,460,266...125,494,760
Ensembl chr 6:125,460,266...125,494,791
JBrowse link
G Cdc42ep5 CDC42 effector protein (Rho GTPase binding) 5 multiple interactions ISO [Disulfiram binds to Copper] which results in increased expression of CDC42EP5 mRNA CTD PMID:24690739 NCBI chr 7:4,151,260...4,164,831
Ensembl chr 7:4,151,260...4,164,860
JBrowse link
G Cdh11 cadherin 11 multiple interactions ISO [Disulfiram binds to Copper] which results in increased expression of CDH11 mRNA CTD PMID:24690739 NCBI chr 8:102,632,095...102,785,493
Ensembl chr 8:102,632,095...102,785,642
JBrowse link
G Cdh2 cadherin 2 multiple interactions ISO [Disulfiram binds to Copper] which results in increased expression of CDH2 mRNA CTD PMID:24690739 NCBI chr18:16,588,877...16,809,246
Ensembl chr18:16,588,877...16,809,246
JBrowse link
G Cdk5r1 cyclin-dependent kinase 5, regulatory subunit 1 (p35) multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of CDK5R1 mRNA CTD PMID:24690739 NCBI chr11:80,477,023...80,481,184
Ensembl chr11:80,477,023...80,481,184
JBrowse link
G Cdk5rap3 CDK5 regulatory subunit associated protein 3 multiple interactions ISO [Disulfiram binds to Copper] which results in increased expression of CDK5RAP3 mRNA CTD PMID:24690739 NCBI chr11:96,907,425...96,916,531
Ensembl chr11:96,907,426...96,916,496
JBrowse link
G Cdkn1b cyclin-dependent kinase inhibitor 1B increases expression
multiple interactions
ISO
EXP
Disulfiram results in increased expression of CDKN1B protein
[Disulfiram binds to Copper] which results in increased expression of CDKN1B protein
CTD PMID:17079463 PMID:24690739 NCBI chr 6:134,920,401...134,925,525
Ensembl chr 6:134,920,401...134,925,513
JBrowse link
G Cdkn1c cyclin-dependent kinase inhibitor 1C (P57) multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of CDKN1C mRNA CTD PMID:24690739 NCBI chr 7:143,458,339...143,461,059
Ensembl chr 7:143,458,339...143,461,050
JBrowse link
G Cdkn2aip CDKN2A interacting protein multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of CDKN2AIP mRNA CTD PMID:24690739 NCBI chr 8:47,709,344...47,713,931
Ensembl chr 8:47,709,344...47,713,932
JBrowse link
G Cemip cell migration inducing protein, hyaluronan binding multiple interactions ISO [Disulfiram binds to Copper] which results in increased expression of CEMIP mRNA CTD PMID:24690739 NCBI chr 7:83,932,857...84,086,693
Ensembl chr 7:83,932,857...84,086,502
JBrowse link
G Cenpw centromere protein W multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of CENPW mRNA CTD PMID:24690739 NCBI chr10:30,196,009...30,200,603
Ensembl chr10:30,194,569...30,200,560
JBrowse link
G Cfap53 cilia and flagella associated protein 53 multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of CFAP53 mRNA CTD PMID:24690739 NCBI chr18:74,283,100...74,359,984
Ensembl chr18:74,283,090...74,359,986
JBrowse link
G Cfb complement factor B multiple interactions ISO [Disulfiram binds to Copper] which results in increased expression of CFB mRNA CTD PMID:24690739 NCBI chr17:34,856,374...34,862,514
Ensembl chr17:34,856,374...34,862,518
JBrowse link
G Chga chromogranin A multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of CHGA mRNA CTD PMID:24690739 NCBI chr12:102,554,941...102,565,027
Ensembl chr12:102,554,969...102,565,028
JBrowse link
G Chmp1b charged multivesicular body protein 1B multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of CHMP1B mRNA CTD PMID:24690739 NCBI chr18:67,205,359...67,207,887
Ensembl chr18:67,205,366...67,207,889
JBrowse link
G Chordc1 cysteine and histidine-rich domain (CHORD)-containing, zinc-binding protein 1 multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of CHORDC1 mRNA CTD PMID:24690739 NCBI chr 9:18,292,267...18,314,000
Ensembl chr 9:18,292,125...18,317,442
JBrowse link
G Cilp cartilage intermediate layer protein, nucleotide pyrophosphohydrolase multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of CILP mRNA CTD PMID:24690739 NCBI chr 9:65,265,180...65,280,614
Ensembl chr 9:65,265,180...65,280,605
JBrowse link
G Cirbp cold inducible RNA binding protein multiple interactions ISO [Disulfiram binds to Copper] which results in increased expression of CIRBP mRNA CTD PMID:24690739 NCBI chr10:80,165,990...80,172,786
Ensembl chr10:80,165,985...80,172,786
JBrowse link
G Ckap4 cytoskeleton-associated protein 4 multiple interactions ISO [Disulfiram binds to Copper] which results in increased expression of CKAP4 mRNA CTD PMID:24690739 NCBI chr10:84,526,305...84,533,888
Ensembl chr10:84,526,305...84,534,062
JBrowse link
G Cldn1 claudin 1 multiple interactions ISO [Disulfiram binds to Copper] which results in increased expression of CLDN1 mRNA CTD PMID:24690739 NCBI chr16:26,356,645...26,371,839
Ensembl chr16:26,356,642...26,371,841
JBrowse link
G Clec7a C-type lectin domain family 7, member a increases expression ISO Disulfiram results in increased expression of CLEC7A protein CTD PMID:32712770 NCBI chr 6:129,461,591...129,472,785
Ensembl chr 6:129,461,591...129,472,779
JBrowse link
G Clp1 CLP1, cleavage and polyadenylation factor I subunit multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of CLP1 mRNA CTD PMID:24690739 NCBI chr 2:84,723,122...84,727,287
Ensembl chr 2:84,722,104...84,727,350
JBrowse link
G Clta clathrin, light polypeptide (Lca) multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of CLTA mRNA CTD PMID:24690739 NCBI chr 4:44,003,816...44,032,846
Ensembl chr 4:44,004,452...44,032,846
JBrowse link
G Cntnap1 contactin associated protein-like 1 multiple interactions ISO [Disulfiram binds to Copper] which results in increased expression of CNTNAP1 mRNA CTD PMID:24690739 NCBI chr11:101,174,617...101,190,724
Ensembl chr11:101,170,523...101,190,724
JBrowse link
G Col12a1 collagen, type XII, alpha 1 multiple interactions ISO [Disulfiram binds to Copper] which results in increased expression of COL12A1 mRNA CTD PMID:24690739 NCBI chr 9:79,598,987...79,721,141
Ensembl chr 9:79,598,991...79,718,831
JBrowse link
G Col1a2 collagen, type I, alpha 2 multiple interactions ISO [Disulfiram binds to Copper] which results in increased expression of COL1A2 mRNA CTD PMID:24690739 NCBI chr 6:4,505,618...4,541,543
Ensembl chr 6:4,504,814...4,541,544
JBrowse link
G Col3a1 collagen, type III, alpha 1 multiple interactions ISO [Disulfiram binds to Copper] which results in increased expression of COL3A1 mRNA CTD PMID:24690739 NCBI chr 1:45,311,538...45,349,706
Ensembl chr 1:45,311,538...45,349,706
JBrowse link
G Col4a1 collagen, type IV, alpha 1 multiple interactions ISO [Disulfiram binds to Copper] which results in increased expression of COL4A1 mRNA CTD PMID:24690739 NCBI chr 8:11,198,423...11,312,889
Ensembl chr 8:11,198,423...11,312,826
JBrowse link
G Col5a1 collagen, type V, alpha 1 multiple interactions ISO [Disulfiram binds to Copper] which results in increased expression of COL5A1 mRNA CTD PMID:24690739 NCBI chr 2:27,886,381...28,039,510
Ensembl chr 2:27,886,425...28,039,514
JBrowse link
G Commd9 COMM domain containing 9 multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of COMMD9 mRNA CTD PMID:24690739 NCBI chr 2:101,886,262...101,901,639
Ensembl chr 2:101,886,247...101,901,646
JBrowse link
G Crabp2 cellular retinoic acid binding protein II multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of CRABP2 mRNA CTD PMID:24690739 NCBI chr 3:87,948,693...87,953,372
Ensembl chr 3:87,948,666...87,953,376
JBrowse link
G Creb1 cAMP responsive element binding protein 1 multiple interactions ISO [Disulfiram co-treated with Copper] results in decreased activity of CREB1 protein; Copper promotes the reaction [Disulfiram results in decreased activity of CREB1 protein] CTD PMID:15367699 NCBI chr 1:64,532,794...64,604,548
Ensembl chr 1:64,532,645...64,604,548
JBrowse link
G Creld2 cysteine-rich with EGF-like domains 2 multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of CRELD2 mRNA CTD PMID:24690739 NCBI chr15:88,819,646...88,826,681
Ensembl chr15:88,819,646...88,826,683
JBrowse link
G Crim1 cysteine rich transmembrane BMP regulator 1 (chordin like) multiple interactions ISO [Disulfiram binds to Copper] which results in increased expression of CRIM1 mRNA CTD PMID:24690739 NCBI chr17:78,200,233...78,376,592
Ensembl chr17:78,200,248...78,376,592
JBrowse link
G Cript cysteine-rich PDZ-binding protein multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of CRIPT mRNA CTD PMID:24690739 NCBI chr17:87,025,561...87,035,808
Ensembl chr17:87,025,550...87,035,810
JBrowse link
G Crispld2 cysteine-rich secretory protein LCCL domain containing 2 multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of CRISPLD2 mRNA CTD PMID:24690739 NCBI chr 8:119,992,438...120,052,794
Ensembl chr 8:119,992,438...120,052,793
JBrowse link
G Cryab crystallin, alpha B multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of CRYAB mRNA CTD PMID:24690739 NCBI chr 9:50,745,951...50,756,636
Ensembl chr 9:50,751,325...50,756,636
JBrowse link
G Cse1l chromosome segregation 1-like (S. cerevisiae) multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of CSE1L mRNA CTD PMID:24690739 NCBI chr 2:166,906,041...166,946,389
Ensembl chr 2:166,906,040...166,946,389
JBrowse link
G Csnk1e casein kinase 1, epsilon multiple interactions ISO [Disulfiram binds to Copper] which results in increased expression of CSNK1E mRNA CTD PMID:24690739 NCBI chr15:79,417,852...79,455,579
Ensembl chr15:79,417,856...79,455,566
JBrowse link
G Csrnp1 cysteine-serine-rich nuclear protein 1 multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of AXUD1 mRNA CTD PMID:24690739 NCBI chr 9:119,971,163...119,984,742
Ensembl chr 9:119,971,163...119,984,658
JBrowse link
G Csrp2 cysteine and glycine-rich protein 2 multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of CSRP2 mRNA CTD PMID:24690739 NCBI chr10:110,920,176...110,939,514
Ensembl chr10:110,919,789...110,939,622
JBrowse link
G Cst6 cystatin E/M multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of CST6 mRNA CTD PMID:24690739 NCBI chr19:5,344,705...5,349,574
Ensembl chr19:5,344,705...5,349,574
JBrowse link
G Cth cystathionase (cystathionine gamma-lyase) increases expression ISO Disulfiram results in increased expression of CTH protein CTD PMID:34242567 NCBI chr 3:157,894,248...157,925,081
Ensembl chr 3:157,894,248...157,925,077
JBrowse link
G Cwc25 CWC25 spliceosome-associated protein multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of CWC25 mRNA CTD PMID:24690739 NCBI chr11:97,745,470...97,766,613
Ensembl chr11:97,745,481...97,766,556
JBrowse link
G Cxcr4 chemokine (C-X-C motif) receptor 4 multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of CXCR4 mRNA CTD PMID:24690739 NCBI chr 1:128,588,199...128,592,299
Ensembl chr 1:128,588,199...128,592,293
JBrowse link
G Cyp17a1 cytochrome P450, family 17, subfamily a, polypeptide 1 multiple interactions EXP Disulfiram inhibits the reaction [[FSHB protein co-treated with LHB protein co-treated with Testosterone] results in increased expression of CYP17A1 mRNA] CTD PMID:22285649 NCBI chr19:46,667,165...46,673,000
Ensembl chr19:46,667,165...46,673,172
JBrowse link
G Cyp19a1 cytochrome P450, family 19, subfamily a, polypeptide 1 multiple interactions EXP Disulfiram inhibits the reaction [[FSHB protein co-treated with LHB protein co-treated with Testosterone] results in increased expression of CYP19A1 mRNA] CTD PMID:22285649 NCBI chr 9:54,165,937...54,268,164
Ensembl chr 9:54,165,937...54,268,110
JBrowse link
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 decreases activity ISO Disulfiram results in decreased activity of CYP1A1 protein CTD PMID:33814510 NCBI chr 9:57,687,928...57,703,824
Ensembl chr 9:57,687,928...57,703,824
JBrowse link
G Cyp1b1 cytochrome P450, family 1, subfamily b, polypeptide 1 decreases activity ISO Disulfiram results in decreased activity of CYP1B1 protein CTD PMID:33814510 NCBI chr17:79,706,940...79,715,061
Ensembl chr17:79,701,537...79,715,061
JBrowse link
G Cyp2b10 cytochrome P450, family 2, subfamily b, polypeptide 10 multiple interactions
increases expression
ISO GH1 protein inhibits the reaction [Disulfiram results in increased expression of CYP2B1 mRNA] CTD PMID:8390837 NCBI chr 7:25,897,658...25,926,624
Ensembl chr 7:25,897,620...25,926,624
JBrowse link
G Cyp2b13 cytochrome P450, family 2, subfamily b, polypeptide 13 increases expression
multiple interactions
ISO Disulfiram results in increased expression of CYP2B2 mRNA
GH1 protein inhibits the reaction [Disulfiram results in increased expression of CYP2B2 mRNA]
CTD PMID:8390837 NCBI chr 7:26,061,388...26,096,197
Ensembl chr 7:26,061,497...26,096,197
JBrowse link
G Cyp2c52-ps cytochrome P450, family 2, subfamily c, polypeptide 52, pseudogene decreases expression
decreases activity
ISO Disulfiram results in decreased expression of CYP2C11 protein
Disulfiram results in decreased activity of CYP2C11 protein
CTD PMID:9393675 NCBI chr19:38,976,662...39,003,627
Ensembl chr19:38,976,647...39,003,289
JBrowse link
G Cyp2e1 cytochrome P450, family 2, subfamily e, polypeptide 1 multiple interactions
decreases activity
decreases expression
ISO
EXP
[Disulfiram results in decreased activity of CYP2E1 protein] which affects the activity of Styrene; Disulfiram inhibits the reaction [[CYP2E1 protein results in increased metabolism of Chlorzoxazone] which results in increased chemical synthesis of 6-hydroxychlorzoxazone]; Disulfiram inhibits the reaction [CYP2E1 protein results in increased chemical synthesis of 6-hydroxychlorzoxazone]; Disulfiram inhibits the reaction [CYP2E1 protein results in increased metabolism of Chlorzoxazone]; Disulfiram inhibits the reaction [CYP2E1 protein results in increased oxidation of Halothane]
Disulfiram results in decreased expression of CYP2E1 mRNA; Disulfiram results in decreased expression of CYP2E1 protein
Disulfiram binds to and results in decreased activity of CYP2E1 protein
CTD PMID:1664256 PMID:8637342 PMID:9393675 PMID:10805064 PMID:18754103 More... NCBI chr 7:140,763,819...140,774,990
Ensembl chr 7:140,763,739...140,774,987
JBrowse link
G Cyp2r1 cytochrome P450, family 2, subfamily r, polypeptide 1 multiple interactions ISO [Disulfiram binds to Copper] which results in increased expression of CYP2R1 mRNA CTD PMID:24690739 NCBI chr 7:114,550,123...114,563,048
Ensembl chr 7:114,549,682...114,562,972
JBrowse link
G Dag1 dystroglycan 1 multiple interactions ISO [Disulfiram binds to Copper] which results in increased expression of DAG1 mRNA CTD PMID:24690739 NCBI chr 9:108,204,861...108,263,977
Ensembl chr 9:108,204,634...108,263,958
JBrowse link
G Dbh dopamine beta hydroxylase decreases activity
affects response to substance
ISO
EXP
Disulfiram results in decreased activity of DBH protein
DBH gene SNP affects the susceptibility to Disulfiram
DBH gene polymorphism affects the susceptibility to Disulfiram
CTD PMID:90468 PMID:16163519 PMID:19462300 NCBI chr 2:27,165,507...27,183,204
Ensembl chr 2:27,165,233...27,183,200
JBrowse link
G Dcaf13 DDB1 and CUL4 associated factor 13 multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of DCAF13 mRNA CTD PMID:24690739 NCBI chr15:39,112,874...39,146,856
Ensembl chr15:39,112,865...39,146,856
JBrowse link
G Dcxr dicarbonyl L-xylulose reductase multiple interactions ISO [Disulfiram co-treated with NADP] binds to DCXR protein CTD PMID:25526675 NCBI chr11:120,724,546...120,727,284
Ensembl chr11:120,725,399...120,727,281
JBrowse link
G Ddit3 DNA-damage inducible transcript 3 multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of DDIT3 mRNA CTD PMID:24690739 NCBI chr10:127,290,793...127,296,291
Ensembl chr10:127,290,774...127,296,288
Ensembl chr10:127,290,774...127,296,288
JBrowse link
G Ddx39a DEAD box helicase 39a multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of DDX39A mRNA CTD PMID:24690739 NCBI chr 8:83,715,177...83,726,904
Ensembl chr 8:83,715,177...83,726,892
JBrowse link
G Ddx60 DExD/H box helicase 60 multiple interactions ISO [Disulfiram binds to Copper] which results in increased expression of DDX60 mRNA CTD PMID:24690739 NCBI chr 8:61,928,073...62,037,704
Ensembl chr 8:61,928,087...62,038,244
JBrowse link
G Dedd2 death effector domain-containing DNA binding protein 2 multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of DEDD2 mRNA CTD PMID:24690739 NCBI chr 7:25,199,912...25,220,614
Ensembl chr 7:25,199,915...25,220,615
JBrowse link
G Dhdh dihydrodiol dehydrogenase (dimeric) multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of DHDH mRNA CTD PMID:24690739 NCBI chr 7:45,472,956...45,488,888
Ensembl chr 7:45,470,987...45,488,805
JBrowse link
G Dhrs2 dehydrogenase/reductase member 2 multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of DHRS2 mRNA CTD PMID:24690739 NCBI chr14:55,222,007...55,241,440
Ensembl chr14:55,222,007...55,241,435
JBrowse link
G Dhrs3 dehydrogenase/reductase (SDR family) member 3 multiple interactions ISO [Disulfiram binds to Copper] which results in increased expression of DHRS3 mRNA CTD PMID:24690739 NCBI chr 4:144,892,534...144,928,209
Ensembl chr 4:144,892,827...144,928,209
JBrowse link
G Dkk3 dickkopf WNT signaling pathway inhibitor 3 multiple interactions ISO [Disulfiram binds to Copper] which results in increased expression of DKK3 mRNA CTD PMID:24690739 NCBI chr 7:112,116,019...112,159,482
Ensembl chr 7:112,116,017...112,159,057
JBrowse link
G Dll1 delta like canonical Notch ligand 1 multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of DLL1 mRNA CTD PMID:24690739 NCBI chr17:15,367,354...15,376,932
Ensembl chr17:15,367,354...15,376,872
JBrowse link
G Dnaja1 DnaJ heat shock protein family (Hsp40) member A1 multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of DNAJA1 mRNA CTD PMID:24690739 NCBI chr 4:40,722,468...40,734,965
Ensembl chr 4:40,722,150...40,737,149
JBrowse link
G Dnaja4 DnaJ heat shock protein family (Hsp40) member A4 multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of DNAJA4 mRNA CTD PMID:24690739 NCBI chr 9:54,698,848...54,716,317
Ensembl chr 9:54,698,873...54,716,315
JBrowse link
G Dnajb1 DnaJ heat shock protein family (Hsp40) member B1 multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of DNAJB1 mRNA CTD PMID:24690739 NCBI chr 8:83,608,175...83,612,653
Ensembl chr 8:83,608,193...83,612,653
JBrowse link
G Dnajb6 DnaJ heat shock protein family (Hsp40) member B6 multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of DNAJB6 mRNA CTD PMID:24690739 NCBI chr 5:29,735,898...29,786,478
Ensembl chr 5:29,735,688...29,818,134
JBrowse link
G Dnajc3 DnaJ heat shock protein family (Hsp40) member C3 multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of DNAJC3 mRNA CTD PMID:24690739 NCBI chr14:118,937,932...118,981,702
Ensembl chr14:118,937,976...118,981,697
JBrowse link
G Dph3 diphthamine biosynthesis 3 multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of DPH3 mRNA CTD PMID:24690739 NCBI chr14:32,080,517...32,085,692
Ensembl chr14:32,080,566...32,085,729
JBrowse link
G Dram1 DNA-damage regulated autophagy modulator 1 multiple interactions ISO [Disulfiram binds to Copper] which results in increased expression of DRAM1 mRNA CTD PMID:24690739 NCBI chr10:88,322,801...88,364,359
Ensembl chr10:88,322,804...88,379,080
JBrowse link
G Dse dermatan sulfate epimerase multiple interactions ISO [Disulfiram binds to Copper] which results in increased expression of DSE mRNA CTD PMID:24690739 NCBI chr10:34,151,389...34,208,282
Ensembl chr10:34,151,393...34,207,715
JBrowse link
G Dusp2 dual specificity phosphatase 2 multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of DUSP2 mRNA CTD PMID:24690739 NCBI chr 2:127,336,159...127,338,377
Ensembl chr 2:127,336,159...127,338,376
JBrowse link
G Dusp5 dual specificity phosphatase 5 multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of DUSP5 mRNA CTD PMID:24690739 NCBI chr19:53,529,145...53,541,809
Ensembl chr19:53,529,109...53,542,431
JBrowse link
G Dynll2 dynein light chain LC8-type 2 multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of DYNLL2 mRNA CTD PMID:24690739 NCBI chr11:87,979,525...88,003,817
Ensembl chr11:87,979,525...87,987,533
JBrowse link
G Eaf1 ELL associated factor 1 multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of EAF1 mRNA CTD PMID:24690739 NCBI chr14:31,495,079...31,509,858
Ensembl chr14:31,494,399...31,509,858
JBrowse link
G Edil3 EGF-like repeats and discoidin I-like domains 3 multiple interactions ISO [Disulfiram binds to Copper] which results in increased expression of EDIL3 mRNA CTD PMID:24690739 NCBI chr13:88,821,472...89,323,225
Ensembl chr13:88,821,472...89,323,223
JBrowse link
G Eed embryonic ectoderm development multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of EED mRNA CTD PMID:24690739 NCBI chr 7:89,954,654...89,980,976
Ensembl chr 7:89,954,654...89,980,983
JBrowse link
G Efemp1 epidermal growth factor-containing fibulin-like extracellular matrix protein 1 multiple interactions ISO [Disulfiram binds to Copper] which results in increased expression of EFEMP1 mRNA CTD PMID:24690739 NCBI chr11:28,853,154...28,926,743
Ensembl chr11:28,853,204...28,926,743
JBrowse link
G Egr1 early growth response 1 multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of EGR1 mRNA CTD PMID:24690739 NCBI chr18:34,861,207...34,864,956
Ensembl chr18:34,859,823...34,864,984
JBrowse link
G Eif4a3 eukaryotic translation initiation factor 4A3 multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of EIF4A3 mRNA CTD PMID:24690739 NCBI chr11:119,288,363...119,300,043
Ensembl chr11:119,288,363...119,300,089
JBrowse link
G Ell2 elongation factor for RNA polymerase II 2 multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of ELL2 mRNA CTD PMID:24690739 NCBI chr13:75,707,484...75,772,361
Ensembl chr13:75,706,757...75,772,364
JBrowse link
G Elof1 ELF1 homolog, elongation factor 1 multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of ELOF1 mRNA CTD PMID:24690739 NCBI chr 9:22,112,986...22,117,195
Ensembl chr 9:22,112,989...22,117,172
JBrowse link
G Esr1 estrogen receptor 1 (alpha) multiple interactions ISO Disulfiram binds to and results in decreased activity of ESR1 protein CTD PMID:33049310 NCBI chr10:4,611,989...5,005,633
Ensembl chr10:4,611,593...5,005,614
JBrowse link
G Ets1 E26 avian leukemia oncogene 1, 5' domain multiple interactions ISO [Disulfiram binds to Copper] which results in increased expression of ETS1 mRNA CTD PMID:24690739 NCBI chr 9:32,636,241...32,757,820
Ensembl chr 9:32,636,221...32,757,820
JBrowse link
G F12 coagulation factor XII (Hageman factor) multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of F12 mRNA CTD PMID:24690739 NCBI chr13:55,417,958...55,426,804
Ensembl chr13:55,417,958...55,426,793
JBrowse link
G Fam210a family with sequence similarity 210, member A multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of FAM210A mRNA CTD PMID:24690739 NCBI chr18:68,260,175...68,300,333
Ensembl chr18:68,260,187...68,300,333
JBrowse link
G Fam234a family with sequence similarity 234, member A multiple interactions ISO [Disulfiram binds to Copper] which results in increased expression of FAM234A mRNA CTD PMID:24690739 NCBI chr17:26,212,692...26,244,307
Ensembl chr17:26,211,822...26,244,242
JBrowse link
G Fam32a family with sequence similarity 32, member A multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of FAM32A mRNA CTD PMID:24690739 NCBI chr 8:72,219,745...72,225,034
Ensembl chr 8:72,219,730...72,224,418
JBrowse link
G Fech ferrochelatase increases expression ISO Disulfiram results in increased expression of FECH mRNA CTD PMID:20566472 NCBI chr18:64,456,542...64,489,098
Ensembl chr18:64,452,914...64,490,251
JBrowse link
G Fkbp1a FK506 binding protein 1a multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of FKBP1A mRNA CTD PMID:24690739 NCBI chr 2:151,542,483...151,561,691
Ensembl chr 2:151,542,483...151,561,692
JBrowse link
G Flcn folliculin multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of FLCN mRNA CTD PMID:24690739 NCBI chr11:59,791,408...59,810,039
Ensembl chr11:59,791,408...59,810,016
JBrowse link
G Fndc11 fibronectin type III domain containing 11 multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of FNDC11 mRNA CTD PMID:24690739 NCBI chr 2:181,212,592...181,222,856
Ensembl chr 2:181,220,013...181,222,854
JBrowse link
G Fos FBJ osteosarcoma oncogene multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of FOS mRNA CTD PMID:24690739 NCBI chr12:85,473,890...85,477,274
Ensembl chr12:85,473,890...85,477,273
JBrowse link
G Fosb FBJ osteosarcoma oncogene B multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of FOSB mRNA CTD PMID:24690739 NCBI chr 7:19,302,696...19,310,118
Ensembl chr 7:19,302,696...19,310,051
JBrowse link
G Foxa3 forkhead box A3 multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of FOXA3 mRNA CTD PMID:24690739 NCBI chr 7:19,013,283...19,023,539
Ensembl chr 7:19,013,284...19,023,538
JBrowse link
G Foxj1 forkhead box J1 multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of FOXJ1 mRNA CTD PMID:24690739 NCBI chr11:116,330,704...116,335,499
Ensembl chr11:116,330,704...116,335,399
JBrowse link
G Frg1 FSHD region gene 1 multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of FRG1 mRNA CTD PMID:24690739 NCBI chr 8:41,389,181...41,417,138
Ensembl chr 8:41,397,459...41,417,074
JBrowse link
G Fshb follicle stimulating hormone beta multiple interactions EXP Disulfiram inhibits the reaction [[FSHB protein co-treated with LHB protein co-treated with Testosterone] results in increased expression of BMP7 mRNA]; Disulfiram inhibits the reaction [[FSHB protein co-treated with LHB protein co-treated with Testosterone] results in increased expression of CCND2 mRNA]; Disulfiram inhibits the reaction [[FSHB protein co-treated with LHB protein co-treated with Testosterone] results in increased expression of CYP17A1 mRNA]; Disulfiram inhibits the reaction [[FSHB protein co-treated with LHB protein co-treated with Testosterone] results in increased expression of CYP19A1 mRNA]; Disulfiram inhibits the reaction [[FSHB protein co-treated with LHB protein co-treated with Testosterone] results in increased expression of FSHR mRNA]; Disulfiram inhibits the reaction [[FSHB protein co-treated with LHB protein co-treated with Testosterone] results in increased expression of LHCGR mRNA]; Tretinoin inhibits the reaction [Disulfiram inhibits the reaction [[FSHB protein co-treated with LHB protein co-treated with Testosterone] results in increased expression of LHCGR mRNA]] CTD PMID:22285649 NCBI chr 2:107,055,986...107,059,651
Ensembl chr 2:107,056,140...107,059,656
JBrowse link
G Fshr follicle stimulating hormone receptor multiple interactions EXP Disulfiram inhibits the reaction [[FSHB protein co-treated with LHB protein co-treated with Testosterone] results in increased expression of FSHR mRNA] CTD PMID:22285649 NCBI chr17:88,984,952...89,200,675
Ensembl chr17:88,984,952...89,200,675
JBrowse link
G Fstl1 follistatin-like 1 multiple interactions ISO [Disulfiram binds to Copper] which results in increased expression of FSTL1 mRNA CTD PMID:24690739 NCBI chr16:37,777,055...37,836,516
Ensembl chr16:37,776,873...37,836,514
JBrowse link
G Ftcd formiminotransferase cyclodeaminase multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of FTCD mRNA CTD PMID:24690739 NCBI chr10:76,575,648...76,590,338
Ensembl chr10:76,575,648...76,590,338
JBrowse link
G Ftl1 ferritin light polypeptide 1 increases expression ISO Disulfiram results in increased expression of FTL mRNA CTD PMID:20566472 NCBI chr 7:45,457,944...45,459,886
Ensembl chr 7:45,457,944...45,459,884
JBrowse link
G G6pdx glucose-6-phosphate dehydrogenase X-linked increases expression ISO Disulfiram results in increased expression of G6PD mRNA CTD PMID:20566472 NCBI chr  X:74,409,483...74,428,880
Ensembl chr  X:74,409,483...74,429,194
JBrowse link
G Gadd45b growth arrest and DNA-damage-inducible 45 beta multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of GADD45B mRNA CTD PMID:24690739 NCBI chr10:80,930,091...80,932,204
Ensembl chr10:80,930,073...80,932,204
JBrowse link
G Galnt10 polypeptide N-acetylgalactosaminyltransferase 10 multiple interactions ISO [Disulfiram binds to Copper] which results in increased expression of GALNT10 mRNA CTD PMID:24690739 NCBI chr11:57,645,442...57,787,514
Ensembl chr11:57,645,442...57,787,514
JBrowse link
G Gas6 growth arrest specific 6 multiple interactions ISO [Disulfiram binds to Copper] which results in increased expression of GAS6 mRNA CTD PMID:24690739 NCBI chr 8:13,465,374...13,494,535
Ensembl chr 8:13,465,374...13,494,490
JBrowse link
G Gata2 GATA binding protein 2 multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of GATA2 mRNA CTD PMID:24690739 NCBI chr 6:88,193,891...88,207,032
Ensembl chr 6:88,193,891...88,207,032
JBrowse link
G Gbp3 guanylate binding protein 3 multiple interactions ISO [Disulfiram binds to Copper] which results in increased expression of GBP4 mRNA CTD PMID:24690739 NCBI chr 3:142,560,016...142,573,213
Ensembl chr 3:142,560,026...142,573,209
JBrowse link
G Gcc1 golgi coiled coil 1 multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of GCC1 mRNA CTD PMID:24690739 NCBI chr 6:28,416,603...28,421,724
Ensembl chr 6:28,416,091...28,428,390
JBrowse link
G Gcgr glucagon receptor multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of GCGR mRNA CTD PMID:24690739 NCBI chr11:120,529,185...120,538,989
Ensembl chr11:120,530,699...120,538,986
JBrowse link
G Gclc glutamate-cysteine ligase, catalytic subunit increases expression ISO Disulfiram results in increased expression of GCLC mRNA CTD PMID:20566472 NCBI chr 9:77,754,535...77,794,489
Ensembl chr 9:77,754,535...77,794,485
JBrowse link
G Gclm glutamate-cysteine ligase, modifier subunit increases expression ISO Disulfiram results in increased expression of GCLM mRNA CTD PMID:20566472 NCBI chr 3:122,245,487...122,267,215
Ensembl chr 3:122,245,557...122,270,732
JBrowse link
G Gem GTP binding protein (gene overexpressed in skeletal muscle) multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of GEM mRNA CTD PMID:24690739 NCBI chr 4:11,704,447...11,714,993
Ensembl chr 4:11,704,457...11,714,752
JBrowse link
G Gemin6 gem nuclear organelle associated protein 6 multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of GEMIN6 mRNA CTD PMID:24690739 NCBI chr17:80,207,504...80,228,497
Ensembl chr17:80,224,441...80,228,497
JBrowse link
G Gh growth hormone multiple interactions ISO GH1 protein inhibits the reaction [Disulfiram results in increased expression of CYP2B1 mRNA]; GH1 protein inhibits the reaction [Disulfiram results in increased expression of CYP2B2 mRNA] CTD PMID:8390837 NCBI chr11:106,300,261...106,303,703
Ensembl chr11:106,300,271...106,301,865
JBrowse link
G Glg1 golgi apparatus protein 1 multiple interactions ISO [Disulfiram binds to Copper] which results in increased expression of GLG1 mRNA CTD PMID:24690739 NCBI chr 8:111,153,284...111,259,210
Ensembl chr 8:111,154,421...111,259,216
JBrowse link
G Glrx2 glutaredoxin 2 (thioltransferase) multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of GLRX2 mRNA CTD PMID:24690739 NCBI chr 1:143,739,224...143,749,678
Ensembl chr 1:143,716,338...143,749,676
JBrowse link
G Gm13889 predicted gene 13889 multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of C11ORF96 mRNA CTD PMID:24690739 NCBI chr 2:93,955,810...93,957,100
Ensembl chr 2:93,955,810...93,957,201
JBrowse link
G Gm40318 predicted gene, 40318 multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of S100P mRNA CTD PMID:24690739 NCBI chr 5:36,762,504...36,767,419
Ensembl chr 5:36,762,617...36,766,695
JBrowse link
G Gm6760 predicted gene 6760 multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of SPANXN5 mRNA CTD PMID:24690739 NCBI chr  X:64,151,405...64,152,198
Ensembl chr  X:64,151,405...64,152,198
JBrowse link
G Gm7030 predicted gene 7030 multiple interactions ISO [Disulfiram binds to Copper] which results in increased expression of HLA-F mRNA CTD PMID:24690739 NCBI chr17:36,127,609...36,129,425
Ensembl chr17:36,109,719...36,129,425
JBrowse link
G Gm7072 predicted gene 7072 multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of ZNF34 mRNA CTD PMID:24690739 NCBI chr17:22,285,871...22,319,979
Ensembl chr17:22,285,871...22,314,837
JBrowse link
G Gosr2 golgi SNAP receptor complex member 2 multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of GOSR2 mRNA CTD PMID:24690739 NCBI chr11:103,676,849...103,697,723
Ensembl chr11:103,676,849...103,697,898
JBrowse link
G Gpr1 G protein-coupled receptor 1 multiple interactions ISO [Disulfiram binds to Copper] which results in increased expression of CMKLR2 mRNA CTD PMID:24690739 NCBI chr 1:63,182,571...63,223,278
Ensembl chr 1:63,182,691...63,214,543
JBrowse link
G Gpsm1 G-protein signalling modulator 1 (AGS3-like, C. elegans) multiple interactions ISO [Disulfiram binds to Copper] which results in increased expression of GPSM1 mRNA CTD PMID:24690739 NCBI chr 2:26,314,611...26,348,237
Ensembl chr 2:26,315,515...26,348,237
JBrowse link
G Gpt2 glutamic pyruvate transaminase (alanine aminotransferase) 2 multiple interactions ISO [Disulfiram binds to Copper] which results in increased expression of GPT2 mRNA CTD PMID:24690739 NCBI chr 8:85,492,576...85,528,902
Ensembl chr 8:85,492,576...85,527,560
JBrowse link
G Gpx3 glutathione peroxidase 3 increases expression ISO Disulfiram results in increased expression of GPX3 mRNA CTD PMID:20566472 NCBI chr11:54,902,854...54,910,387
Ensembl chr11:54,902,453...54,910,377
JBrowse link
G Gramd1a GRAM domain containing 1A multiple interactions ISO [Disulfiram binds to Copper] which results in increased expression of GRAMD1A mRNA CTD PMID:24690739 NCBI chr 7:31,130,127...31,155,935
Ensembl chr 7:31,130,127...31,155,896
JBrowse link
G Gramd3 GRAM domain containing 3 multiple interactions ISO [Disulfiram binds to Copper] which results in increased expression of GRAMD2B mRNA CTD PMID:24690739 NCBI chr18:56,387,485...56,503,792
Ensembl chr18:56,400,337...56,503,792
JBrowse link
G Grwd1 glutamate-rich WD repeat containing 1 multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of GRWD1 mRNA CTD PMID:24690739 NCBI chr 7:45,825,223...45,830,994
Ensembl chr 7:45,825,223...45,830,944
JBrowse link
G Gsdme gasdermin E multiple interactions ISO [Disulfiram binds to Copper] which results in increased expression of GSDME mRNA CTD PMID:24690739 NCBI chr 6:50,207,401...50,263,857
Ensembl chr 6:50,188,888...50,263,862
JBrowse link
G Gsr glutathione reductase increases expression ISO Disulfiram results in increased expression of GSR mRNA CTD PMID:20566472 NCBI chr 8:33,653,238...33,698,162
Ensembl chr 8:33,652,523...33,698,163
JBrowse link
G Gtf2b general transcription factor IIB multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of GTF2B mRNA CTD PMID:24690739 NCBI chr 3:142,765,247...142,783,606
Ensembl chr 3:142,765,045...142,783,606
JBrowse link
G H2-M2 histocompatibility 2, M region locus 2 multiple interactions ISO [Disulfiram binds to Copper] which results in increased expression of HLA-B mRNA CTD PMID:24690739 NCBI chr17:37,480,851...37,483,554
Ensembl chr17:37,480,851...37,483,552
JBrowse link
G H2ac20 H2A clustered histone 20 multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of H2AC20 mRNA CTD PMID:24690739 NCBI chr 3:96,220,413...96,220,880
Ensembl chr 3:96,220,361...96,220,880
JBrowse link
G H2ax H2A.X variant histone multiple interactions ISO Disulfiram inhibits the reaction [propylene dichloride results in increased phosphorylation of H2AX protein] CTD PMID:28300663 NCBI chr 9:44,334,715...44,336,077
Ensembl chr 9:44,334,694...44,336,077
JBrowse link
G H2bc12 H2B clustered histone 12 multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of H2BC12 mRNA CTD PMID:24690739 NCBI chr13:22,035,821...22,036,320
Ensembl chr13:22,035,870...22,036,345
JBrowse link
G H2bc8 H2B clustered histone 8 multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of H2BC8 mRNA CTD PMID:24690739 NCBI chr13:23,571,400...23,571,863
Ensembl chr13:23,571,396...23,572,013
JBrowse link
G H3c8 H3 clustered histone 8 multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of H3C12 mRNA CTD PMID:24690739 NCBI chr13:23,535,418...23,535,909
Ensembl chr13:23,535,422...23,535,951
JBrowse link
G H3f4 H3.4 histone multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of H3-4 mRNA CTD PMID:24690739 NCBI chr11:58,961,711...58,962,273
Ensembl chr11:58,961,812...58,962,222
JBrowse link
G H6pd hexose-6-phosphate dehydrogenase (glucose 1-dehydrogenase) multiple interactions ISO [Disulfiram binds to Copper] which results in increased expression of H6PD mRNA CTD PMID:24690739 NCBI chr 4:149,979,474...150,009,023
Ensembl chr 4:149,979,475...150,009,023
JBrowse link
G Hba-a1 hemoglobin alpha, adult chain 1 multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of HBA1 mRNA CTD PMID:24690739 NCBI chr11:32,283,672...32,284,486
Ensembl chr11:32,283,511...32,284,465
JBrowse link
G Hbegf heparin-binding EGF-like growth factor multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of HBEGF mRNA CTD PMID:24690739 NCBI chr18:36,504,927...36,515,805
Ensembl chr18:36,504,927...36,515,805
JBrowse link
G Hes1 hes family bHLH transcription factor 1 multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of HES1 mRNA CTD PMID:24690739 NCBI chr16:30,065,357...30,067,796
Ensembl chr16:30,064,384...30,067,796
JBrowse link
G Hes6 hairy and enhancer of split 6 multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of HES6 mRNA CTD PMID:24690739 NCBI chr 1:91,411,483...91,414,038
Ensembl chr 1:91,411,483...91,414,038
JBrowse link
G Hmox1 heme oxygenase 1 increases expression
multiple interactions
ISO Disulfiram results in increased expression of HMOX1 mRNA
[Disulfiram binds to Copper] which results in decreased expression of HMOX1 mRNA; [Disulfiram co-treated with Zinc Sulfate] results in increased expression of HMOX1 mRNA; MTF1 protein affects the reaction [Disulfiram results in increased expression of HMOX1 mRNA]
CTD PMID:20566472 PMID:24690739 PMID:32661532 PMID:32712770 NCBI chr 8:75,093,618...75,100,593
Ensembl chr 8:75,093,621...75,100,589
JBrowse link
G Hnrnpa2b1 heterogeneous nuclear ribonucleoprotein A2/B1 multiple interactions ISO [Disulfiram binds to Copper] which results in increased expression of HNRNPA2B1 mRNA CTD PMID:24690739 NCBI chr 6:51,460,434...51,470,048
Ensembl chr 6:51,460,932...51,469,894
JBrowse link
G Hoxa1 homeobox A1 multiple interactions EXP Disulfiram inhibits the reaction [Vitamin A results in increased expression of HOXA1 mRNA] CTD PMID:23696197 NCBI chr 6:52,155,367...52,160,007
Ensembl chr 6:52,155,590...52,158,317
JBrowse link
G Hoxd1 homeobox D1 multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of HOXD1 mRNA CTD PMID:24690739 NCBI chr 2:74,762,980...74,765,142
Ensembl chr 2:74,762,980...74,765,142
JBrowse link
G Hrk harakiri, BCL2 interacting protein (contains only BH3 domain) multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of HRK mRNA CTD PMID:24690739 NCBI chr 5:118,169,764...118,189,478
Ensembl chr 5:118,164,648...118,189,478
JBrowse link
G Hs3st2 heparan sulfate (glucosamine) 3-O-sulfotransferase 2 multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of HS3ST2 mRNA CTD PMID:24690739 NCBI chr 7:121,391,585...121,501,768
Ensembl chr 7:121,391,859...121,501,770
JBrowse link
G Hsd11b1 hydroxysteroid 11-beta dehydrogenase 1 multiple interactions ISO [Disulfiram co-treated with NAD] binds to HSD11B1 protein CTD PMID:25526675 NCBI chr 1:193,221,640...193,264,045
Ensembl chr 1:193,221,634...193,264,075
JBrowse link
G Hsd11b2 hydroxysteroid 11-beta dehydrogenase 2 decreases activity ISO Disulfiram results in decreased activity of HSD11B2 protein CTD PMID:22796344 NCBI chr 8:105,518,746...105,523,988
Ensembl chr 8:105,518,755...105,523,988
JBrowse link
G Hsp90aa1 heat shock protein 90, alpha (cytosolic), class A member 1 multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of HSP90AA1 mRNA CTD PMID:24690739 NCBI chr12:110,691,036...110,696,395
Ensembl chr12:110,690,605...110,702,728
JBrowse link
G Hsp90ab1 heat shock protein 90 alpha (cytosolic), class B member 1 multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of HSP90AB1 mRNA CTD PMID:24690739 NCBI chr17:45,567,778...45,573,261
Ensembl chr17:45,567,775...45,573,271
JBrowse link
G Hspa1a heat shock protein 1A multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of HSPA1A mRNA CTD PMID:24690739 NCBI chr17:34,969,359...34,972,156
Ensembl chr17:34,969,190...34,972,156
JBrowse link
G Hspa1b heat shock protein 1B increases expression
multiple interactions
ISO Disulfiram results in increased expression of HSPA1B mRNA
[Disulfiram binds to Copper] which results in decreased expression of HSPA1B mRNA
CTD PMID:20566472 PMID:24690739 NCBI chr17:34,956,429...34,959,238
Ensembl chr17:34,956,436...34,959,238
JBrowse link
G Hspa1l heat shock protein 1-like multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of HSPA1L mRNA CTD PMID:24690739 NCBI chr17:34,972,703...34,979,228
Ensembl chr17:34,972,703...34,979,285
JBrowse link
G Hspa4 heat shock protein 4 multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of HSPA4 mRNA CTD PMID:24690739 NCBI chr11:53,259,814...53,300,479
Ensembl chr11:53,259,814...53,300,457
JBrowse link
G Hspa8 heat shock protein 8 multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of HSPA8 mRNA CTD PMID:24690739 NCBI chr 9:40,801,276...40,805,202
Ensembl chr 9:40,800,984...40,810,087
JBrowse link
G Hspb1 heat shock protein 1 multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of HSPB1 mRNA CTD PMID:24690739 NCBI chr 5:135,887,919...135,889,563
Ensembl chr 5:135,887,919...135,889,563
JBrowse link
G Hspb8 heat shock protein 8 multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of HSPB8 mRNA CTD PMID:24690739 NCBI chr 5:116,408,491...116,422,864
Ensembl chr 5:116,408,491...116,422,864
JBrowse link
G Hsph1 heat shock 105kDa/110kDa protein 1 multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of HSPH1 mRNA CTD PMID:24690739 NCBI chr 5:149,616,843...149,636,498
Ensembl chr 5:149,614,287...149,636,376
JBrowse link
G Htr2b 5-hydroxytryptamine (serotonin) receptor 2B multiple interactions ISO [Disulfiram binds to Copper] which results in increased expression of HTR2B mRNA CTD PMID:24690739 NCBI chr 1:86,097,546...86,116,231
Ensembl chr 1:86,099,026...86,111,970
JBrowse link
G Id2 inhibitor of DNA binding 2 multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of ID2 mRNA CTD PMID:24690739 NCBI chr12:25,093,799...25,096,092
Ensembl chr12:25,093,799...25,097,140
JBrowse link
G Ier5 immediate early response 5 multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of IER5 mRNA CTD PMID:24690739 NCBI chr 1:155,096,367...155,099,636
Ensembl chr 1:155,096,361...155,099,636
JBrowse link
G Ifit2 interferon-induced protein with tetratricopeptide repeats 2 multiple interactions ISO [Disulfiram binds to Copper] which results in increased expression of IFIT2 mRNA CTD PMID:24690739 NCBI chr19:34,550,550...34,576,534
Ensembl chr19:34,550,694...34,576,419
JBrowse link
G Ifit3 interferon-induced protein with tetratricopeptide repeats 3 multiple interactions ISO [Disulfiram binds to Copper] which results in increased expression of IFIT3 mRNA CTD PMID:24690739 NCBI chr19:34,583,119...34,588,982
Ensembl chr19:34,583,531...34,588,731
JBrowse link
G Ifngr2 interferon gamma receptor 2 multiple interactions ISO [Disulfiram binds to Copper] which results in increased expression of IFNGR2 mRNA CTD PMID:24690739 NCBI chr16:91,547,059...91,564,007
Ensembl chr16:91,547,072...91,565,623
JBrowse link
G Igf2os insulin-like growth factor 2, opposite strand multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of IGF2-AS mRNA CTD PMID:24690739 NCBI chr 7:142,659,680...142,670,356
Ensembl chr 7:142,659,693...142,670,356
JBrowse link
G Igf2r insulin-like growth factor 2 receptor multiple interactions ISO [Disulfiram binds to Copper] which results in increased expression of IGF2R mRNA CTD PMID:24690739 NCBI chr17:12,682,406...12,769,706
Ensembl chr17:12,682,406...12,769,664
JBrowse link
G Igfbp7 insulin-like growth factor binding protein 7 multiple interactions ISO [Disulfiram binds to Copper] which results in increased expression of IGFBP7 mRNA; [Disulfiram binds to Copper] which results in increased expression of IGFBP7 protein CTD PMID:24690739 NCBI chr 5:77,349,240...77,408,045
Ensembl chr 5:77,349,240...77,408,041
JBrowse link
G Il1a interleukin 1 alpha multiple interactions ISO [Disulfiram binds to Copper] which results in increased expression of IL1A mRNA CTD PMID:24690739 NCBI chr 2:129,299,609...129,310,186
Ensembl chr 2:129,299,610...129,309,972
JBrowse link
G Il1b interleukin 1 beta multiple interactions ISO [Disulfiram binds to Copper] which results in increased expression of IL1B mRNA; [Disulfiram co-treated with Zinc Sulfate] inhibits the reaction [Lipopolysaccharides results in increased secretion of IL1B protein] CTD PMID:24690739 PMID:32712770 NCBI chr 2:129,364,569...129,371,164
Ensembl chr 2:129,364,570...129,371,139
JBrowse link
G Il6 interleukin 6 multiple interactions ISO [Disulfiram binds to Copper] which results in increased expression of IL6 mRNA; [Disulfiram co-treated with Zinc Sulfate] inhibits the reaction [Lipopolysaccharides results in increased secretion of IL6 protein] CTD PMID:24690739 PMID:32712770 NCBI chr 5:30,013,114...30,019,975
Ensembl chr 5:30,013,114...30,019,981
JBrowse link
G Insig1 insulin induced gene 1 multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of INSIG1 mRNA CTD PMID:24690739 NCBI chr 5:28,071,412...28,078,662
Ensembl chr 5:28,071,363...28,078,662
JBrowse link
G Irf8 interferon regulatory factor 8 multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of IRF8 mRNA CTD PMID:24690739 NCBI chr 8:120,736,358...120,756,694
Ensembl chr 8:120,736,358...120,756,694
JBrowse link
G Isy1 ISY1 splicing factor homolog multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of ISY1 mRNA CTD PMID:24690739 NCBI chr 6:87,818,447...87,838,923
Ensembl chr 6:87,814,269...87,838,798
JBrowse link
G Itga11 integrin alpha 11 multiple interactions ISO [Disulfiram binds to Copper] which results in increased expression of ITGA11 mRNA CTD PMID:24690739 NCBI chr 9:62,677,855...62,783,979
Ensembl chr 9:62,677,826...62,783,982
JBrowse link
G Itga3 integrin alpha 3 multiple interactions ISO [Disulfiram binds to Copper] which results in increased expression of ITGA3 mRNA CTD PMID:24690739 NCBI chr11:95,044,475...95,076,844
Ensembl chr11:95,044,474...95,076,801
JBrowse link
G Itgam integrin alpha M increases expression ISO Disulfiram results in increased expression of ITGAM protein CTD PMID:32712770 NCBI chr 7:128,062,640...128,118,491
Ensembl chr 7:128,062,640...128,118,491
JBrowse link
G Itgav integrin alpha V multiple interactions ISO [Disulfiram binds to Copper] which results in increased expression of ITGAV mRNA CTD PMID:24690739 NCBI chr 2:83,722,303...83,806,917
Ensembl chr 2:83,724,397...83,806,916
JBrowse link
G Itgb1 integrin beta 1 (fibronectin receptor beta) multiple interactions ISO [Disulfiram binds to Copper] which results in increased expression of ITGB1 mRNA CTD PMID:24690739 NCBI chr 8:128,685,654...128,733,579
Ensembl chr 8:128,685,654...128,733,200
JBrowse link
G Itgb5 integrin beta 5 multiple interactions ISO [Disulfiram binds to Copper] which results in increased expression of ITGB5 mRNA CTD PMID:24690739 NCBI chr16:33,829,665...33,949,338
Ensembl chr16:33,829,665...33,949,338
JBrowse link
G Jag2 jagged 2 multiple interactions ISO [Disulfiram binds to Copper] which results in increased expression of JAG2 mRNA CTD PMID:24690739 NCBI chr12:112,907,803...112,929,812
Ensembl chr12:112,907,819...112,929,776
JBrowse link
G Jun jun proto-oncogene multiple interactions ISO [Copper co-treated with Disulfiram co-treated with gemcitabine] results in increased expression of and results in increased phosphorylation of JUN protein; [Copper co-treated with Disulfiram] results in increased expression of and results in increased phosphorylation of JUN protein; [Disulfiram co-treated with cupric chloride co-treated with Doxorubicin] results in increased expression of and results in increased phosphorylation of JUN protein; Acetylcysteine inhibits the reaction [[Copper co-treated with Disulfiram] results in increased phosphorylation of JUN protein]; pyrazolanthrone inhibits the reaction [[Disulfiram co-treated with Copper co-treated with Doxorubicin] results in increased phosphorylation of and results in increased expression of JUN protein] CTD PMID:21911303 PMID:23033007 NCBI chr 4:95,049,036...95,052,222
Ensembl chr 4:95,049,034...95,052,222
JBrowse link
G Kcng1 potassium voltage-gated channel, subfamily G, member 1 multiple interactions ISO [Disulfiram binds to Copper] which results in increased expression of KCNG1 mRNA CTD PMID:24690739 NCBI chr 2:168,260,117...168,281,533
Ensembl chr 2:168,260,117...168,281,736
JBrowse link
G Khdrbs3 KH domain containing, RNA binding, signal transduction associated 3 multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of KHDRBS3 mRNA CTD PMID:24690739 NCBI chr15:68,928,392...69,101,794
Ensembl chr15:68,928,420...69,101,211
JBrowse link
G Klf10 Kruppel-like factor 10 multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of KLF10 mRNA CTD PMID:24690739 NCBI chr15:38,291,464...38,300,711
Ensembl chr15:38,291,463...38,300,706
JBrowse link
G Klhl22 kelch-like 22 multiple interactions ISO [Disulfiram binds to Copper] which results in increased expression of KLHL22 mRNA CTD PMID:24690739 NCBI chr16:17,759,621...17,793,382
Ensembl chr16:17,759,618...17,793,382
JBrowse link
G Klhl5 kelch-like 5 multiple interactions ISO [Disulfiram binds to Copper] which results in increased expression of KLHL5 mRNA CTD PMID:24690739 NCBI chr 5:65,107,551...65,168,173
Ensembl chr 5:65,107,539...65,168,188
JBrowse link
G Krt75 keratin 75 multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of KRT75 mRNA CTD PMID:24690739 NCBI chr15:101,563,343...101,573,904
Ensembl chr15:101,563,345...101,573,904
JBrowse link
G Lamc1 laminin, gamma 1 multiple interactions ISO [Disulfiram binds to Copper] which results in increased expression of LAMC1 mRNA CTD PMID:24690739 NCBI chr 1:153,218,922...153,332,786
Ensembl chr 1:153,218,922...153,332,786
JBrowse link
G Lamtor3 late endosomal/lysosomal adaptor, MAPK and MTOR activator 3 multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of LAMTOR3 mRNA CTD PMID:24690739 NCBI chr 3:137,918,555...137,928,762
Ensembl chr 3:137,918,506...137,928,900
JBrowse link
G Lemd2 LEM domain containing 2 multiple interactions ISO [Disulfiram binds to Copper] which results in increased expression of LEMD2 mRNA CTD PMID:24690739 NCBI chr17:27,189,600...27,205,470
Ensembl chr17:27,189,600...27,204,469
JBrowse link
G Lhb luteinizing hormone beta multiple interactions EXP Disulfiram inhibits the reaction [[FSHB protein co-treated with LHB protein co-treated with Testosterone] results in increased expression of BMP7 mRNA]; Disulfiram inhibits the reaction [[FSHB protein co-treated with LHB protein co-treated with Testosterone] results in increased expression of CCND2 mRNA]; Disulfiram inhibits the reaction [[FSHB protein co-treated with LHB protein co-treated with Testosterone] results in increased expression of CYP17A1 mRNA]; Disulfiram inhibits the reaction [[FSHB protein co-treated with LHB protein co-treated with Testosterone] results in increased expression of CYP19A1 mRNA]; Disulfiram inhibits the reaction [[FSHB protein co-treated with LHB protein co-treated with Testosterone] results in increased expression of FSHR mRNA]; Disulfiram inhibits the reaction [[FSHB protein co-treated with LHB protein co-treated with Testosterone] results in increased expression of LHCGR mRNA]; Tretinoin inhibits the reaction [Disulfiram inhibits the reaction [[FSHB protein co-treated with LHB protein co-treated with Testosterone] results in increased expression of LHCGR mRNA]] CTD PMID:22285649 NCBI chr 7:45,417,608...45,421,855
Ensembl chr 7:45,420,820...45,421,897
Ensembl chr 7:45,420,820...45,421,897
JBrowse link
G Lhcgr luteinizing hormone/choriogonadotropin receptor multiple interactions EXP Disulfiram inhibits the reaction [[FSHB protein co-treated with LHB protein co-treated with Testosterone] results in increased expression of LHCGR mRNA]; Tretinoin inhibits the reaction [Disulfiram inhibits the reaction [[FSHB protein co-treated with LHB protein co-treated with Testosterone] results in increased expression of LHCGR mRNA]] CTD PMID:22285649 NCBI chr17:88,716,384...88,792,059
Ensembl chr17:88,716,481...88,791,990
JBrowse link
G Limch1 LIM and calponin homology domains 1 multiple interactions ISO [Disulfiram binds to Copper] which results in increased expression of LIMCH1 mRNA CTD PMID:24690739 NCBI chr 5:66,745,889...67,057,159
Ensembl chr 5:66,745,827...67,057,158
JBrowse link
G Lipt1 lipoyltransferase 1 multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of LIPT1 mRNA CTD PMID:24690739 NCBI chr 1:37,871,738...37,876,228
Ensembl chr 1:37,871,738...37,876,228
JBrowse link
G Lmcd1 LIM and cysteine-rich domains 1 multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of LMCD1 mRNA CTD PMID:24690739 NCBI chr 6:112,273,758...112,330,423
Ensembl chr 6:112,273,758...112,330,425
JBrowse link
G Lmtk2 lemur tyrosine kinase 2 multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of LMTK2 mRNA CTD PMID:24690739 NCBI chr 5:144,100,361...144,188,208
Ensembl chr 5:144,100,436...144,188,204
JBrowse link
G Lor loricrin multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of LORICRIN mRNA CTD PMID:24690739 NCBI chr 3:92,080,271...92,083,142
Ensembl chr 3:92,080,271...92,083,142
JBrowse link
G Lratd2 LRAT domain containing 1 multiple interactions ISO [Disulfiram binds to Copper] which results in increased expression of LRATD2 mRNA CTD PMID:24690739 NCBI chr15:60,818,996...60,826,105
Ensembl chr15:60,818,994...60,853,778
JBrowse link
G Lrp8 low density lipoprotein receptor-related protein 8, apolipoprotein e receptor multiple interactions ISO [Disulfiram binds to Copper] which results in increased expression of LRP8 mRNA CTD PMID:24690739 NCBI chr 4:107,802,200...107,876,840
Ensembl chr 4:107,801,869...107,876,840
JBrowse link
G Lsmem1 leucine-rich single-pass membrane protein 1 multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of LSMEM1 mRNA CTD PMID:24690739 NCBI chr12:40,176,386...40,199,315
Ensembl chr12:40,175,493...40,199,490
JBrowse link
G Ltb4r1 leukotriene B4 receptor 1 multiple interactions ISO [Disulfiram binds to Copper] which results in increased expression of LTB4R mRNA CTD PMID:24690739 NCBI chr14:55,765,962...55,768,492
Ensembl chr14:55,765,962...55,768,494
JBrowse link
G Luc7l3 LUC7-like 3 (S. cerevisiae) multiple interactions ISO [Disulfiram binds to Copper] which results in increased expression of CROP mRNA CTD PMID:24690739 NCBI chr11:94,291,073...94,322,329
Ensembl chr11:94,287,890...94,321,988
JBrowse link
G Macf1 microtubule-actin crosslinking factor 1 multiple interactions ISO [Disulfiram binds to Copper] which results in increased expression of MACF1 mRNA CTD PMID:24690739 NCBI chr 4:123,349,633...123,687,802
Ensembl chr 4:123,349,633...123,684,360
JBrowse link
G Mad2l1bp MAD2L1 binding protein multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of MAD2L1BP mRNA CTD PMID:24690739 NCBI chr17:46,147,385...46,153,551
Ensembl chr17:46,147,387...46,153,553
JBrowse link
G Mafb v-maf musculoaponeurotic fibrosarcoma oncogene family, protein B (avian) multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of MAFB mRNA CTD PMID:24690739 NCBI chr 2:160,363,677...160,367,065
Ensembl chr 2:160,363,703...160,367,065
JBrowse link
G Maff v-maf musculoaponeurotic fibrosarcoma oncogene family, protein F (avian) increases expression ISO Disulfiram results in increased expression of MAFF mRNA CTD PMID:20566472 NCBI chr15:79,346,621...79,359,078
Ensembl chr15:79,346,621...79,359,076
JBrowse link
G Mafg v-maf musculoaponeurotic fibrosarcoma oncogene family, protein G (avian) increases expression ISO Disulfiram results in increased expression of MAFG mRNA CTD PMID:20566472 NCBI chr11:120,625,117...120,634,955
Ensembl chr11:120,625,117...120,633,600
JBrowse link
G Mafk v-maf musculoaponeurotic fibrosarcoma oncogene family, protein K (avian) increases expression ISO Disulfiram results in increased expression of MAFK mRNA CTD PMID:20566472 NCBI chr 5:139,791,536...139,802,653
Ensembl chr 5:139,791,513...139,802,653
JBrowse link
G Magoh mago homolog, exon junction complex core component multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of MAGOH mRNA CTD PMID:24690739 NCBI chr 4:107,879,755...107,887,424
Ensembl chr 4:107,879,755...107,887,424
JBrowse link
G Man1b1 mannosidase, alpha, class 1B, member 1 multiple interactions ISO [Disulfiram binds to Copper] which results in increased expression of MAN1B1 mRNA CTD PMID:24690739 NCBI chr 2:25,332,730...25,352,213
Ensembl chr 2:25,332,338...25,352,212
JBrowse link
G Maoa monoamine oxidase A multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of MAOA mRNA CTD PMID:24690739 NCBI chr  X:16,619,698...16,687,812
Ensembl chr  X:16,619,698...16,687,818
JBrowse link
G Map1lc3b microtubule-associated protein 1 light chain 3 beta multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of MAP1LC3B mRNA CTD PMID:24690739 NCBI chr 8:121,590,438...121,598,760
Ensembl chr 8:121,590,361...121,598,760
JBrowse link
G Map2k3 mitogen-activated protein kinase kinase 3 multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of MAP2K3 mRNA CTD PMID:24690739 NCBI chr11:60,932,054...60,952,811
Ensembl chr11:60,932,033...60,952,811
JBrowse link
G Map3k13 mitogen-activated protein kinase kinase kinase 13 multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of MAP3K13 mRNA CTD PMID:24690739 NCBI chr16:21,824,056...21,933,439
Ensembl chr16:21,794,346...21,933,439
JBrowse link
G Map3k20 mitogen-activated protein kinase kinase kinase 20 multiple interactions ISO [Disulfiram binds to Copper] which results in increased expression of MAP3K20 mRNA CTD PMID:24690739 NCBI chr 2:72,285,637...72,442,610
Ensembl chr 2:72,285,637...72,442,610
JBrowse link
G Mapk1 mitogen-activated protein kinase 1 multiple interactions ISO [Copper co-treated with Disulfiram co-treated with gemcitabine] results in increased phosphorylation of MAPK1 protein; [Copper co-treated with Disulfiram] results in increased phosphorylation of MAPK1 protein CTD PMID:23033007 NCBI chr16:16,983,382...17,047,453
Ensembl chr16:16,983,382...17,047,453
JBrowse link
G Mapk3 mitogen-activated protein kinase 3 multiple interactions ISO [Copper co-treated with Disulfiram co-treated with gemcitabine] results in increased phosphorylation of MAPK3 protein; [Copper co-treated with Disulfiram] results in increased phosphorylation of MAPK3 protein CTD PMID:23033007 NCBI chr 7:126,759,626...126,765,816
Ensembl chr 7:126,759,601...126,765,819
JBrowse link
G Mapk8 mitogen-activated protein kinase 8 multiple interactions ISO
EXP
[Disulfiram binds to cupric chloride] which results in increased activity of MAPK8 protein; bathocuproine sulfonate inhibits the reaction [[Disulfiram binds to cupric chloride] which results in increased activity of MAPK8 protein]
[Disulfiram binds to Copper] which results in increased phosphorylation of MAPK8 protein
CTD PMID:11239917 PMID:24690739 NCBI chr14:33,377,898...33,447,353
Ensembl chr14:33,377,898...33,447,158
JBrowse link
G Mapk9 mitogen-activated protein kinase 9 multiple interactions ISO
EXP
[Disulfiram binds to Copper] which results in increased phosphorylation of MAPK9 protein CTD PMID:24690739 NCBI chr11:49,846,728...49,886,421
Ensembl chr11:49,846,751...49,886,421
JBrowse link
G Mapre2 microtubule-associated protein, RP/EB family, member 2 multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of MAPRE2 mRNA CTD PMID:24690739 NCBI chr18:23,752,333...23,893,861
Ensembl chr18:23,752,333...23,893,861
JBrowse link
G Mcm2 minichromosome maintenance complex component 2 multiple interactions
decreases expression
ISO cupric chloride promotes the reaction [Disulfiram results in decreased expression of MCM2 mRNA] CTD PMID:19789329 NCBI chr 6:88,883,474...88,898,780
Ensembl chr 6:88,883,474...88,898,780
JBrowse link
G Mcm5 minichromosome maintenance complex component 5 multiple interactions
decreases expression
ISO cupric chloride promotes the reaction [Disulfiram results in decreased expression of MCM5 mRNA] CTD PMID:19789329 NCBI chr 8:75,109,468...75,128,439
Ensembl chr 8:75,109,569...75,128,439
JBrowse link
G Me1 malic enzyme 1, NADP(+)-dependent, cytosolic increases expression ISO Disulfiram results in increased expression of ME1 mRNA CTD PMID:20566472 NCBI chr 9:86,581,363...86,695,914
Ensembl chr 9:86,581,371...86,695,953
JBrowse link
G Mfsd3 major facilitator superfamily domain containing 3 multiple interactions ISO [Disulfiram binds to Copper] which results in increased expression of MFSD3 mRNA CTD PMID:24690739 NCBI chr15:76,701,542...76,704,239
Ensembl chr15:76,701,465...76,704,239
JBrowse link
G Mgmt O-6-methylguanine-DNA methyltransferase multiple interactions
decreases activity
increases degradation
ISO
EXP
[Disulfiram binds to Copper] which results in decreased expression of and results in decreased activity of MGMT protein; [Disulfiram co-treated with cupric chloride] affects the expression of and affects the activity of MGMT protein; bortezomib inhibits the reaction [Disulfiram results in increased degradation of MGMT protein]; Disulfiram inhibits the reaction [O(6)-benzylguanine binds to MGMT protein]; Disulfiram results in decreased expression of and results in decreased activity of MGMT protein
Disulfiram results in decreased activity of MGMT protein
CTD PMID:24193513 NCBI chr 7:136,894,463...137,128,193
Ensembl chr 7:136,894,614...137,130,266
JBrowse link
G Mgst1 microsomal glutathione S-transferase 1 increases expression ISO Disulfiram results in increased expression of MGST1 mRNA CTD PMID:20566472 NCBI chr 6:138,140,527...138,156,755
Ensembl chr 6:138,140,316...138,156,755
JBrowse link
G Midn midnolin multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of MIDN mRNA CTD PMID:24690739 NCBI chr10:80,146,005...80,158,368
Ensembl chr10:80,148,272...80,158,368
JBrowse link
G Mmp10 matrix metallopeptidase 10 multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of MMP10 mRNA CTD PMID:24690739 NCBI chr 9:7,502,342...7,510,242
Ensembl chr 9:7,502,352...7,510,240
JBrowse link
G Mmp2 matrix metallopeptidase 2 decreases expression ISO Disulfiram results in decreased expression of MMP2 CTD PMID:18047805 NCBI chr 8:92,827,290...92,853,421
Ensembl chr 8:92,827,291...92,853,420
JBrowse link
G Mmp3 matrix metallopeptidase 3 multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of MMP3 mRNA CTD PMID:24690739 NCBI chr 9:7,445,822...7,455,975
Ensembl chr 9:7,445,822...7,455,975
JBrowse link
G Mmp9 matrix metallopeptidase 9 decreases expression ISO Disulfiram results in decreased expression of MMP9 CTD PMID:18047805 NCBI chr 2:164,940,326...164,955,850
Ensembl chr 2:164,940,780...164,955,850
JBrowse link
G Mppe1 metallophosphoesterase 1 multiple interactions ISO [Disulfiram binds to Copper] which results in increased expression of MPPE1 mRNA CTD PMID:24690739 NCBI chr18:67,225,043...67,245,830
Ensembl chr18:67,225,043...67,245,830
JBrowse link
G Mrpl10 mitochondrial ribosomal protein L10 multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of MRPL10 mRNA CTD PMID:24690739 NCBI chr11:97,041,582...97,049,213
Ensembl chr11:97,041,560...97,049,213
JBrowse link
G Mrpl18 mitochondrial ribosomal protein L18 multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of MRPL18 mRNA CTD PMID:24690739 NCBI chr17:12,911,345...12,917,787
Ensembl chr17:12,911,349...12,916,345
JBrowse link
G Mrpl45 mitochondrial ribosomal protein L45 multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of MRPL45 mRNA CTD PMID:24690739 NCBI chr11:97,314,923...97,329,920
Ensembl chr11:97,315,716...97,329,920
JBrowse link
G mt-Co1 cytochrome c oxidase I, mitochondrial affects activity
affects expression
ISO Disulfiram affects the activity of COX1 protein
Disulfiram affects the expression of COX1 mRNA
CTD PMID:17936468 NCBI chr MT:5,328...6,872
Ensembl chr MT:5,328...6,872
JBrowse link
G Mt1 metallothionein 1 increases expression
multiple interactions
ISO Disulfiram results in increased expression of MT1X mRNA
[Disulfiram binds to Copper] which results in decreased expression of MT1X mRNA; cupric chloride promotes the reaction [Disulfiram results in increased expression of MT1X mRNA]
CTD PMID:19789329 PMID:20566472 PMID:24690739 NCBI chr 8:94,178,883...94,180,327
Ensembl chr 8:94,179,082...94,180,327
JBrowse link
G Mt2 metallothionein 2 multiple interactions
increases expression
ISO cupric chloride promotes the reaction [Disulfiram results in increased expression of MT2A mRNA]; MTF1 protein affects the reaction [Disulfiram results in increased expression of MT2A mRNA] CTD PMID:19789329 PMID:32661532 NCBI chr 8:94,172,618...94,173,567
Ensembl chr 8:94,172,664...94,173,568
JBrowse link
G Mt3 metallothionein 3 multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of MT3 mRNA CTD PMID:24690739 NCBI chr 8:94,152,607...94,154,148
Ensembl chr 8:94,152,607...94,154,146
JBrowse link
G Mtf1 metal response element binding transcription factor 1 multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of MTF1 mRNA; MTF1 protein affects the reaction [Disulfiram results in increased expression of ATF3 mRNA]; MTF1 protein affects the reaction [Disulfiram results in increased expression of HMOX1 mRNA]; MTF1 protein affects the reaction [Disulfiram results in increased expression of MT1M mRNA]; MTF1 protein affects the reaction [Disulfiram results in increased expression of MT2A mRNA] CTD PMID:24690739 PMID:32661532 NCBI chr 4:124,802,549...124,849,800
Ensembl chr 4:124,802,104...124,849,800
JBrowse link
G Mx1 MX dynamin-like GTPase 1 multiple interactions ISO [Disulfiram binds to Copper] which results in increased expression of MX1 mRNA CTD PMID:24690739 NCBI chr16:97,447,035...97,462,906
Ensembl chr16:97,447,035...97,462,907
JBrowse link
G Mylip myosin regulatory light chain interacting protein multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of MYLIP mRNA CTD PMID:24690739 NCBI chr13:45,389,742...45,411,940
Ensembl chr13:45,389,742...45,412,022
JBrowse link
G Mylk myosin, light polypeptide kinase multiple interactions ISO [Disulfiram binds to Copper] which results in increased expression of MYLK mRNA CTD PMID:24690739 NCBI chr16:34,745,199...35,002,436
Ensembl chr16:34,745,210...35,002,420
JBrowse link
G Nat14 N-acetyltransferase 14 multiple interactions ISO [Disulfiram binds to Copper] which results in increased expression of NAT14 mRNA CTD PMID:24690739 NCBI chr 7:4,918,877...4,925,006
Ensembl chr 7:4,922,028...4,925,006
JBrowse link
G Nceh1 neutral cholesterol ester hydrolase 1 multiple interactions ISO [Disulfiram binds to Copper] which results in increased expression of NCEH1 mRNA CTD PMID:24690739 NCBI chr 3:27,183,004...27,245,266
Ensembl chr 3:27,182,965...27,284,608
JBrowse link
G Ncoa7 nuclear receptor coactivator 7 multiple interactions ISO [Disulfiram binds to Copper] which results in increased expression of NCOA7 mRNA CTD PMID:24690739 NCBI chr10:30,645,582...30,807,700
Ensembl chr10:30,628,999...30,803,326
JBrowse link
G Ncstn nicastrin multiple interactions ISO [Disulfiram binds to Copper] which results in increased expression of NCSTN mRNA CTD PMID:24690739 NCBI chr 1:172,066,013...172,082,789
Ensembl chr 1:172,066,013...172,082,795
JBrowse link
G Nefh neurofilament, heavy polypeptide multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of NEFH mRNA CTD PMID:24690739 NCBI chr11:4,938,754...4,948,064
Ensembl chr11:4,938,754...4,948,064
JBrowse link
G Nfe2l3 nuclear factor, erythroid derived 2, like 3 multiple interactions ISO [Disulfiram binds to Copper] which results in increased expression of NFE2L3 mRNA CTD PMID:24690739 NCBI chr 6:51,432,669...51,458,772
Ensembl chr 6:51,432,670...51,458,768
JBrowse link
G Nfkb1 nuclear factor of kappa light polypeptide gene enhancer in B cells 1, p105 multiple interactions ISO [Disulfiram binds to Copper] which results in increased expression of NFKB1 mRNA CTD PMID:24690739 NCBI chr 3:135,584,655...135,691,969
Ensembl chr 3:135,584,655...135,691,547
JBrowse link
G Nfkbia nuclear factor of kappa light polypeptide gene enhancer in B cells inhibitor, alpha decreases degradation
multiple interactions
ISO
EXP
Disulfiram results in decreased degradation of NFKBIA protein
[Disulfiram binds to Copper] which results in increased expression of NFKBIA protein
CTD PMID:10418820 PMID:24690739 NCBI chr12:55,489,409...55,492,647
Ensembl chr12:55,489,410...55,492,647
JBrowse link
G Nfkbib nuclear factor of kappa light polypeptide gene enhancer in B cells inhibitor, beta multiple interactions ISO
EXP
[Disulfiram binds to Copper] which results in increased expression of NFKBIB protein CTD PMID:24690739 NCBI chr 7:28,758,251...28,766,644
Ensembl chr 7:28,758,251...28,767,512
JBrowse link
G Ngdn neuroguidin, EIF4E binding protein multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of NGDN mRNA CTD PMID:24690739 NCBI chr14:55,015,454...55,024,138
Ensembl chr14:55,015,454...55,024,137
JBrowse link
G Niban1 niban apoptosis regulator 1 multiple interactions ISO [Disulfiram binds to Copper] which results in increased expression of NIBAN1 mRNA CTD PMID:24690739 NCBI chr 1:151,571,373...151,721,432
Ensembl chr 1:151,571,186...151,721,939
JBrowse link
G Nol12 nucleolar protein 12 multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of NOL12 mRNA CTD PMID:24690739 NCBI chr15:78,934,933...78,941,910
Ensembl chr15:78,934,933...78,943,638
JBrowse link
G Nos2 nitric oxide synthase 2, inducible affects expression ISO Disulfiram affects the expression of NOS2 mRNA CTD PMID:17936468 NCBI chr11:78,920,787...78,960,226
Ensembl chr11:78,920,787...78,960,254
JBrowse link
G Nosip nitric oxide synthase interacting protein multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of NOSIP mRNA CTD PMID:24690739 NCBI chr 7:45,062,417...45,078,503
Ensembl chr 7:45,062,429...45,078,210
JBrowse link
G Npepl1 aminopeptidase-like 1 multiple interactions ISO [Disulfiram binds to Copper] which results in increased expression of NPEPL1 mRNA CTD PMID:24690739 NCBI chr 2:174,110,338...174,122,702
Ensembl chr 2:174,110,349...174,123,070
JBrowse link
G Nppb natriuretic peptide type B multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of NPPB mRNA CTD PMID:24690739 NCBI chr 4:147,985,786...147,987,205
Ensembl chr 4:147,985,788...147,987,205
JBrowse link
G Nptx2 neuronal pentraxin 2 multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of NPTX2 mRNA CTD PMID:24690739 NCBI chr 5:144,545,887...144,557,478
Ensembl chr 5:144,545,902...144,557,478
JBrowse link
G Nqo1 NAD(P)H dehydrogenase, quinone 1 increases expression
increases activity
ISO Disulfiram results in increased expression of NQO1 mRNA
Disulfiram results in increased activity of NQO1 protein
CTD PMID:16045903 PMID:20566472 NCBI chr 8:107,388,225...107,403,205
Ensembl chr 8:107,388,225...107,403,206
JBrowse link
G Nr1i2 nuclear receptor subfamily 1, group I, member 2 multiple interactions ISO
EXP
Disulfiram binds to and results in increased activity of NR1I2 protein
Disulfiram binds to and affects the activity of NR1I2 protein
CTD PMID:33049310 NCBI chr16:38,248,349...38,294,849
Ensembl chr16:38,248,323...38,294,824
JBrowse link
G Nrarp Notch-regulated ankyrin repeat protein multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of NRARP mRNA CTD PMID:24690739 NCBI chr 2:25,180,758...25,183,339
Ensembl chr 2:25,180,758...25,183,339
JBrowse link
G Nras neuroblastoma ras oncogene multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of NRAS mRNA CTD PMID:24690739 NCBI chr 3:103,058,285...103,067,914
Ensembl chr 3:103,058,285...103,067,914
JBrowse link
G Nrp1 neuropilin 1 multiple interactions ISO [Disulfiram binds to Copper] which results in increased expression of NRP1 mRNA CTD PMID:24690739 NCBI chr 8:128,358,591...128,505,476
Ensembl chr 8:128,358,604...128,503,363
JBrowse link
G Nt5e 5' nucleotidase, ecto multiple interactions ISO [Disulfiram binds to Copper] which results in increased expression of NT5E mRNA CTD PMID:24690739 NCBI chr 9:88,327,609...88,372,089
Ensembl chr 9:88,327,197...88,372,092
JBrowse link
G Nubp1 nucleotide binding protein 1 multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of NUBP1 mRNA CTD PMID:24690739 NCBI chr16:10,411,884...10,424,453
Ensembl chr16:10,411,948...10,424,428
JBrowse link
G Nxf1 nuclear RNA export factor 1 multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of NXF1 mRNA CTD PMID:24690739 NCBI chr19:8,757,103...8,770,910
Ensembl chr19:8,757,073...8,770,922
JBrowse link
G Nxt2 nuclear transport factor 2-like export factor 2 multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of NXT2 mRNA CTD PMID:24690739 NCBI chr  X:142,226,770...142,239,700
Ensembl chr  X:142,226,770...142,239,692
JBrowse link
G Oasl1 2'-5' oligoadenylate synthetase-like 1 multiple interactions ISO [Disulfiram binds to Copper] which results in increased expression of OASL mRNA CTD PMID:24690739 NCBI chr 5:114,923,143...114,937,911
Ensembl chr 5:114,923,240...114,937,915
JBrowse link
G Osmr oncostatin M receptor multiple interactions ISO [Disulfiram binds to Copper] which results in increased expression of OSMR mRNA CTD PMID:24690739 NCBI chr15:6,813,568...6,874,968
Ensembl chr15:6,813,577...6,874,969
JBrowse link
G P3h3 prolyl 3-hydroxylase 3 multiple interactions ISO [Disulfiram binds to Copper] which results in increased expression of P3H3 mRNA CTD PMID:24690739 NCBI chr 6:124,841,089...124,857,746
Ensembl chr 6:124,841,089...124,857,752
JBrowse link
G P3h4 prolyl 3-hydroxylase family member 4 (non-enzymatic) multiple interactions ISO [Disulfiram binds to Copper] which results in increased expression of P3H4 mRNA CTD PMID:24690739 NCBI chr11:100,408,467...100,414,716
Ensembl chr11:100,408,456...100,414,836
JBrowse link
G Pam peptidylglycine alpha-amidating monooxygenase increases activity ISO Disulfiram results in increased activity of PAM protein CTD PMID:8246921 PMID:10347250 NCBI chr 1:97,821,091...98,095,853
Ensembl chr 1:97,795,114...98,095,646
JBrowse link
G Parp1 poly (ADP-ribose) polymerase family, member 1 multiple interactions
increases cleavage
ISO
EXP
[Copper co-treated with Disulfiram] results in increased cleavage of PARP1 protein; [Disulfiram binds to Copper] which results in increased cleavage of PARP1 protein; [Disulfiram co-treated with cupric chloride] results in increased cleavage of PARP1 protein; Disulfiram promotes the reaction [Carmustine results in increased cleavage of PARP1 protein]
Disulfiram results in increased cleavage of PARP1 protein
CTD PMID:17079463 PMID:19789329 PMID:23033007 PMID:24193513 PMID:24690739 NCBI chr 1:180,568,891...180,600,999
Ensembl chr 1:180,568,924...180,601,254
JBrowse link
G Pck2 phosphoenolpyruvate carboxykinase 2 (mitochondrial) multiple interactions ISO [Disulfiram binds to Copper] which results in increased expression of PCK2 mRNA CTD PMID:24690739 NCBI chr14:55,540,263...55,550,020
Ensembl chr14:55,540,266...55,551,242
JBrowse link
G Pcnx4 pecanex homolog 4 multiple interactions ISO [Disulfiram binds to Copper] which results in increased expression of PCNX4 mRNA CTD PMID:24690739 NCBI chr12:72,536,152...72,580,213
Ensembl chr12:72,536,383...72,580,119
JBrowse link
G Pde5a phosphodiesterase 5A, cGMP-specific multiple interactions ISO [Disulfiram binds to Copper] which results in increased expression of PDE5A mRNA CTD PMID:24690739 NCBI chr 3:122,729,158...122,859,374
Ensembl chr 3:122,728,947...122,859,374
JBrowse link
G Pdgfrb platelet derived growth factor receptor, beta polypeptide multiple interactions ISO [Disulfiram binds to Copper] which results in increased expression of PDGFRB mRNA CTD PMID:24690739 NCBI chr18:61,045,127...61,085,067
Ensembl chr18:61,045,150...61,085,061
JBrowse link
G Pdlim5 PDZ and LIM domain 5 multiple interactions ISO [Disulfiram binds to Copper] which results in increased expression of PDLIM5 mRNA CTD PMID:24690739 NCBI chr 3:142,239,585...142,395,719
Ensembl chr 3:142,239,590...142,395,696
JBrowse link
G Pdpn podoplanin multiple interactions EXP
ISO
[Disulfiram binds to Copper] which results in increased expression of PDPN protein
[Disulfiram binds to Copper] which results in increased expression of and results in increased phosphorylation of and results in increased ubiquitination of PDPN protein
CTD PMID:24690739 NCBI chr 4:143,267,409...143,299,564
Ensembl chr 4:143,267,431...143,299,564
JBrowse link
G Pdrg1 p53 and DNA damage regulated 1 multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of PDRG1 mRNA CTD PMID:24690739 NCBI chr 2:153,008,890...153,016,019
Ensembl chr 2:153,008,890...153,015,427
JBrowse link
G Pgd phosphogluconate dehydrogenase increases expression ISO Disulfiram results in increased expression of PGD mRNA CTD PMID:20566472 NCBI chr 4:149,149,991...149,166,705
Ensembl chr 4:149,149,991...149,166,771
JBrowse link
G Phlda2 pleckstrin homology like domain, family A, member 2 multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of PHLDA2 mRNA CTD PMID:24690739 NCBI chr 7:143,501,545...143,503,145
Ensembl chr 7:143,501,545...143,503,150
JBrowse link
G Phldb2 pleckstrin homology like domain, family B, member 2 multiple interactions ISO [Disulfiram binds to Copper] which results in increased expression of PHLDB2 mRNA CTD PMID:24690739 NCBI chr16:45,746,230...45,953,598
Ensembl chr16:45,746,243...45,953,598
JBrowse link
G Pigq phosphatidylinositol glycan anchor biosynthesis, class Q multiple interactions ISO [Disulfiram binds to Copper] which results in increased expression of PIGQ mRNA CTD PMID:24690739 NCBI chr17:25,926,420...25,942,881
Ensembl chr17:25,926,421...25,944,936
JBrowse link
G Pik3ip1 phosphoinositide-3-kinase interacting protein 1 multiple interactions ISO [Disulfiram binds to Copper] which results in increased expression of PIK3IP1 mRNA CTD PMID:24690739 NCBI chr11:3,319,241...3,342,971
Ensembl chr11:3,330,401...3,342,971
JBrowse link
G Pip4k2a phosphatidylinositol-5-phosphate 4-kinase, type II, alpha multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of PIP4K2A mRNA CTD PMID:24690739 NCBI chr 2:18,842,255...18,998,291
Ensembl chr 2:18,842,255...18,998,126
JBrowse link
G Plod2 procollagen lysine, 2-oxoglutarate 5-dioxygenase 2 multiple interactions ISO [Disulfiram binds to Copper] which results in increased expression of PLOD2 mRNA CTD PMID:24690739 NCBI chr 9:92,539,636...92,608,428
Ensembl chr 9:92,542,223...92,608,428
JBrowse link
G Plpbp pyridoxal phosphate binding protein multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of PLPBP mRNA CTD PMID:24690739 NCBI chr 8:27,041,924...27,056,132
Ensembl chr 8:27,042,555...27,056,132
JBrowse link
G Plscr4 phospholipid scramblase 4 multiple interactions ISO [Disulfiram binds to Copper] which results in increased expression of PLSCR4 mRNA CTD PMID:24690739 NCBI chr 9:92,457,372...92,493,513
Ensembl chr 9:92,457,373...92,492,456
JBrowse link
G Plxnb2 plexin B2 multiple interactions ISO [Disulfiram binds to Copper] which results in increased expression of PLXNB2 mRNA CTD PMID:24690739 NCBI chr15:89,155,546...89,182,018
Ensembl chr15:89,155,549...89,180,788
JBrowse link
G Pnldc1 poly(A)-specific ribonuclease (PARN)-like domain containing 1 multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of PNLDC1 mRNA CTD PMID:24690739 NCBI chr17:12,888,723...12,910,580
Ensembl chr17:12,888,729...12,910,230
JBrowse link
G Pnma2 paraneoplastic antigen MA2 multiple interactions ISO [Disulfiram binds to Copper] which results in increased expression of PNMA2 mRNA CTD PMID:24690739 NCBI chr14:66,901,589...66,920,063
Ensembl chr14:66,911,170...66,921,023
JBrowse link
G Polr2c polymerase (RNA) II (DNA directed) polypeptide C multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of POLR2C mRNA CTD PMID:24690739 NCBI chr 8:94,857,450...94,864,242
Ensembl chr 8:94,857,450...94,873,535
JBrowse link
G Polr2m polymerase (RNA) II (DNA directed) polypeptide M multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of POLR2M mRNA CTD PMID:24690739 NCBI chr 9:71,478,437...71,485,983
Ensembl chr 9:71,478,437...71,485,935
JBrowse link
G Pomc pro-opiomelanocortin-alpha decreases expression ISO Disulfiram results in decreased expression of POMC protein alternative form CTD PMID:8246921 NCBI chr12:3,954,945...3,960,643
Ensembl chr12:3,954,951...3,960,642
JBrowse link
G Pop4 processing of precursor 4, ribonuclease P/MRP family, (S. cerevisiae) multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of POP4 mRNA CTD PMID:24690739 NCBI chr 7:38,262,812...38,271,393
Ensembl chr 7:38,261,996...38,271,423
JBrowse link
G Postn periostin, osteoblast specific factor multiple interactions ISO [Disulfiram binds to Copper] which results in increased expression of POSTN mRNA CTD PMID:24690739 NCBI chr 3:54,359,267...54,391,041
Ensembl chr 3:54,361,109...54,391,037
JBrowse link
G Pparg peroxisome proliferator activated receptor gamma affects expression
multiple interactions
ISO
EXP
Disulfiram affects the expression of PPARG mRNA
Disulfiram binds to and results in increased activity of PPARG protein
CTD PMID:32712770 PMID:33049310 NCBI chr 6:115,360,879...115,490,404
Ensembl chr 6:115,360,951...115,490,399
JBrowse link
G Ppia peptidylprolyl isomerase A multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of PPIA mRNA CTD PMID:24690739 NCBI chr11:6,415,867...6,419,817
Ensembl chr11:6,415,443...6,419,817
JBrowse link
G Ppp1r15a protein phosphatase 1, regulatory subunit 15A multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of PPP1R15A mRNA CTD PMID:24690739 NCBI chr 7:45,522,917...45,526,268
Ensembl chr 7:45,522,916...45,526,268
JBrowse link
G Ppp1r3c protein phosphatase 1, regulatory subunit 3C multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of PPP1R3C mRNA CTD PMID:24690739 NCBI chr19:36,731,731...36,736,604
Ensembl chr19:36,731,731...36,736,653
JBrowse link
G Ppp2r2b protein phosphatase 2, regulatory subunit B, beta multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of PPP2R2B mRNA CTD PMID:24690739 NCBI chr18:42,645,207...43,059,471
Ensembl chr18:42,637,432...43,059,471
Ensembl chr18:42,637,432...43,059,471
JBrowse link
G Prok2 prokineticin 2 multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of PROK2 mRNA CTD PMID:24690739 NCBI chr 6:99,711,299...99,726,392
Ensembl chr 6:99,711,299...99,726,392
JBrowse link
G Prss8 protease, serine 8 (prostasin) multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of PRSS8 mRNA CTD PMID:24690739 NCBI chr 7:127,925,717...127,930,149
Ensembl chr 7:127,925,716...127,930,104
JBrowse link
G Psat1 phosphoserine aminotransferase 1 multiple interactions ISO [Disulfiram binds to Copper] which results in increased expression of PSAT1 mRNA CTD PMID:24690739 NCBI chr19:15,905,123...15,925,059
Ensembl chr19:15,904,678...15,947,337
JBrowse link
G Psmc4 proteasome (prosome, macropain) 26S subunit, ATPase, 4 multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of PSMC4 mRNA CTD PMID:24690739 NCBI chr 7:28,041,702...28,050,092
Ensembl chr 7:28,041,707...28,050,101
JBrowse link
G Pspn persephin multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of PSPN mRNA CTD PMID:24690739 NCBI chr17:56,999,313...57,000,105
Ensembl chr17:56,999,457...57,000,018
JBrowse link
G Pten phosphatase and tensin homolog multiple interactions ISO [Copper co-treated with Disulfiram] results in decreased expression of PTEN protein CTD PMID:20424113 NCBI chr19:32,757,577...32,826,160
Ensembl chr19:32,757,497...32,826,160
JBrowse link
G Ptges3 prostaglandin E synthase 3 multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of PTGES3 mRNA CTD PMID:24690739 NCBI chr10:128,058,982...128,077,254
Ensembl chr10:128,058,954...128,077,272
JBrowse link
G Ptgr1 prostaglandin reductase 1 increases expression ISO Disulfiram results in increased expression of PTGR1 mRNA CTD PMID:20566472 NCBI chr 4:58,965,590...58,987,131
Ensembl chr 4:58,965,439...58,987,119
JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 decreases expression ISO Disulfiram results in decreased expression of PTGS2 mRNA CTD PMID:10418820 NCBI chr 1:150,100,031...150,108,234
Ensembl chr 1:150,100,031...150,108,227
JBrowse link
G Ptma prothymosin alpha multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of PTMA mRNA CTD PMID:24690739 NCBI chr 1:86,526,557...86,530,712
Ensembl chr 1:86,526,726...86,530,712
JBrowse link
G Ptx3 pentraxin related gene multiple interactions ISO [Disulfiram binds to Copper] which results in increased expression of PTX3 mRNA CTD PMID:24690739 NCBI chr 3:66,219,887...66,225,806
Ensembl chr 3:66,219,910...66,225,805
JBrowse link
G Rab5c RAB5C, member RAS oncogene family multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of RAB5C mRNA CTD PMID:24690739 NCBI chr11:100,715,003...100,738,215
Ensembl chr11:100,715,009...100,738,215
JBrowse link
G Rac1 Rac family small GTPase 1 multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of RAC1 mRNA CTD PMID:24690739 NCBI chr 5:143,505,481...143,528,031
Ensembl chr 5:143,503,634...143,528,036
JBrowse link
G Rai2 retinoic acid induced 2 multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of RAI2 mRNA CTD PMID:24690739 NCBI chr  X:161,717,036...161,779,494
Ensembl chr  X:161,717,069...161,779,496
JBrowse link
G Ramac RNA guanine-7 methyltransferase activating subunit multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of RAMAC mRNA CTD PMID:24690739 NCBI chr 7:81,762,953...81,769,490
Ensembl chr 7:81,762,925...81,769,491
JBrowse link
G Rasa1 RAS p21 protein activator 1 multiple interactions ISO [Disulfiram binds to Copper] which results in increased expression of RASA1 mRNA CTD PMID:24690739 NCBI chr13:85,214,699...85,289,486
Ensembl chr13:85,214,780...85,289,130
JBrowse link
G Rasd1 RAS, dexamethasone-induced 1 multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of RASD1 mRNA CTD PMID:24690739 NCBI chr11:59,963,181...59,964,944
Ensembl chr11:59,963,181...59,964,944
JBrowse link
G Rasl11b RAS-like, family 11, member B multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of RASL11B mRNA CTD PMID:24690739 NCBI chr 5:74,195,326...74,199,477
Ensembl chr 5:74,195,286...74,199,481
JBrowse link
G Rbis ribosomal biogenesis factor multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of RBIS mRNA CTD PMID:24690739 NCBI chr 3:14,606,289...14,611,256
Ensembl chr 3:14,606,284...14,611,285
JBrowse link
G Rbm18 RNA binding motif protein 18 multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of RBM18 mRNA CTD PMID:24690739 NCBI chr 2:36,116,079...36,136,704
Ensembl chr 2:36,116,079...36,136,773
JBrowse link
G Rbm48 RNA binding motif protein 48 multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of RBM48 mRNA CTD PMID:24690739 NCBI chr 5:3,583,978...3,598,090
Ensembl chr 5:3,583,978...3,596,585
JBrowse link
G Rep15 RAB15 effector protein multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of REP15 mRNA CTD PMID:24690739 NCBI chr 6:147,032,537...147,033,518
Ensembl chr 6:147,032,584...147,034,245
JBrowse link
G Rftn1 raftlin lipid raft linker 1 multiple interactions ISO [Disulfiram binds to Copper] which results in increased expression of RFTN1 mRNA CTD PMID:24690739 NCBI chr17:49,993,258...50,190,497
Ensembl chr17:49,992,257...50,190,674
JBrowse link
G Rftn2 raftlin family member 2 multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of RFTN2 mRNA CTD PMID:24690739 NCBI chr 1:55,170,159...55,227,063
Ensembl chr 1:55,170,159...55,226,782
JBrowse link
G Rgcc regulator of cell cycle multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of RGCC mRNA CTD PMID:24690739 NCBI chr14:79,288,750...79,301,635
Ensembl chr14:79,288,756...79,301,645
JBrowse link
G Rgs11 regulator of G-protein signaling 11 multiple interactions ISO [Disulfiram binds to Copper] which results in increased expression of RGS11 mRNA CTD PMID:24690739 NCBI chr17:26,202,527...26,211,324
Ensembl chr17:26,202,951...26,211,324
JBrowse link
G Rgs16 regulator of G-protein signaling 16 multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of RGS16 mRNA CTD PMID:24690739 NCBI chr 1:153,740,353...153,745,468
Ensembl chr 1:153,740,349...153,745,468
JBrowse link
G Rgs2 regulator of G-protein signaling 2 multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of RGS2 mRNA CTD PMID:24690739 NCBI chr 1:143,999,338...144,004,149
Ensembl chr 1:143,999,338...144,004,161
JBrowse link
G Rhbdf1 rhomboid 5 homolog 1 multiple interactions ISO [Disulfiram binds to Copper] which results in increased expression of RHBDF1 mRNA CTD PMID:24690739 NCBI chr11:32,209,585...32,222,331
Ensembl chr11:32,209,585...32,222,300
JBrowse link
G Rhbdf2 rhomboid 5 homolog 2 multiple interactions ISO [Disulfiram binds to Copper] which results in increased expression of RHBDF2 mRNA CTD PMID:24690739 NCBI chr11:116,598,148...116,626,960
Ensembl chr11:116,598,165...116,627,019
JBrowse link
G Rhob ras homolog family member B multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of RHOB mRNA CTD PMID:24690739 NCBI chr12:8,497,661...8,500,009
Ensembl chr12:8,497,661...8,500,009
JBrowse link
G Rnf207 ring finger protein 207 multiple interactions ISO [Disulfiram binds to Copper] which results in increased expression of RNF207 mRNA CTD PMID:24690739 NCBI chr 4:152,307,018...152,319,076
Ensembl chr 4:152,307,019...152,318,993
JBrowse link
G Rpl23 ribosomal protein L23 multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of RPL23 mRNA CTD PMID:24690739 NCBI chr11:97,777,526...97,782,439
Ensembl chr11:97,777,527...97,782,437
JBrowse link
G Rpl29 ribosomal protein L29 multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of RPL29 mRNA CTD PMID:24690739 NCBI chr 9:106,428,889...106,431,568
Ensembl chr 9:106,429,454...106,431,568
JBrowse link
G Rpl38 ribosomal protein L38 multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of RPL38 mRNA CTD PMID:24690739 NCBI chr11:114,667,818...114,672,333
Ensembl chr11:114,668,524...114,672,331
JBrowse link
G Rps15 ribosomal protein S15 multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of RPS15 mRNA CTD PMID:24690739 NCBI chr10:80,292,431...80,294,114
Ensembl chr10:80,292,453...80,294,114
JBrowse link
G Rps7 ribosomal protein S7 multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of RPS7 mRNA CTD PMID:24690739 NCBI chr12:28,630,847...28,635,953
Ensembl chr12:28,630,854...28,635,953
JBrowse link
G Rrad Ras-related associated with diabetes multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of RRAD mRNA CTD PMID:24690739 NCBI chr 8:104,628,070...104,631,350
Ensembl chr 8:104,628,070...104,631,327
JBrowse link
G Rragd Ras-related GTP binding D multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of RRAGD mRNA CTD PMID:24690739 NCBI chr 4:32,982,998...33,022,180
Ensembl chr 4:32,983,037...33,022,180
JBrowse link
G Rras related RAS viral (r-ras) oncogene multiple interactions ISO [Disulfiram binds to Copper] which results in increased expression of RRAS mRNA CTD PMID:24690739 NCBI chr 7:45,017,942...45,021,646
Ensembl chr 7:45,017,961...45,021,647
JBrowse link
G Rsad2 radical S-adenosyl methionine domain containing 2 multiple interactions ISO [Disulfiram binds to Copper] which results in increased expression of RSAD2 mRNA CTD PMID:24690739 NCBI chr12:26,442,743...26,456,452
Ensembl chr12:26,442,746...26,456,452
JBrowse link
G Runx2 runt related transcription factor 2 increases expression ISO Disulfiram results in increased expression of RUNX2 mRNA CTD PMID:24496638 NCBI chr17:44,495,987...44,814,797
Ensembl chr17:44,495,987...44,814,797
JBrowse link
G Rybp RING1 and YY1 binding protein multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of RYBP mRNA CTD PMID:24690739 NCBI chr 6:100,228,565...100,287,358
Ensembl chr 6:100,228,565...100,287,485
JBrowse link
G Sap18 Sin3-associated polypeptide 18 multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of SAP18 mRNA CTD PMID:24690739 NCBI chr14:57,798,189...57,804,980
Ensembl chr14:57,798,180...57,806,638
JBrowse link
G Sar1b secretion associated Ras related GTPase 1B multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of SAR1B mRNA CTD PMID:24690739 NCBI chr11:51,763,663...51,791,953
Ensembl chr11:51,763,687...51,791,925
JBrowse link
G Sat1 spermidine/spermine N1-acetyl transferase 1 multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of SAT1 mRNA CTD PMID:24690739 NCBI chr  X:155,213,126...155,216,449
Ensembl chr  X:155,213,132...155,216,449
JBrowse link
G Sbds SBDS ribosome maturation factor multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of SBDS mRNA CTD PMID:24690739 NCBI chr 5:130,245,732...130,255,530
Ensembl chr 5:130,245,731...130,255,530
JBrowse link
G Scarf2 scavenger receptor class F, member 2 multiple interactions ISO [Disulfiram binds to Copper] which results in increased expression of SCARF2 mRNA CTD PMID:24690739 NCBI chr16:17,797,282...17,808,294
Ensembl chr16:17,797,282...17,808,293
JBrowse link
G Scnm1 sodium channel modifier 1 multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of SCNM1 mRNA CTD PMID:24690739 NCBI chr 3:95,129,719...95,134,050
Ensembl chr 3:95,129,536...95,134,011
JBrowse link
G Sec61b Sec61 beta subunit multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of SEC61B mRNA CTD PMID:24690739 NCBI chr 4:47,474,661...47,483,233
Ensembl chr 4:47,474,658...47,483,242
JBrowse link
G Sel1l3 sel-1 suppressor of lin-12-like 3 (C. elegans) multiple interactions ISO [Disulfiram binds to Copper] which results in increased expression of SEL1L3 mRNA CTD PMID:24690739 NCBI chr 5:53,107,083...53,213,452
Ensembl chr 5:53,107,083...53,213,927
JBrowse link
G Sem1 SEM1, 26S proteasome complex subunit multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of SEM1 mRNA CTD PMID:24690739 NCBI chr 6:6,558,275...6,578,658
Ensembl chr 6:6,557,294...6,578,663
JBrowse link
G Sertad1 SERTA domain containing 1 multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of SERTAD1 mRNA CTD PMID:24690739 NCBI chr 7:27,486,953...27,490,316
Ensembl chr 7:27,486,910...27,490,316
JBrowse link
G Sf3b4 splicing factor 3b, subunit 4 multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of SF3B4 mRNA CTD PMID:24690739 NCBI chr 3:96,172,506...96,177,564
Ensembl chr 3:96,172,332...96,177,564
JBrowse link
G Sgta small glutamine-rich tetratricopeptide repeat (TPR)-containing, alpha multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of SGTA mRNA CTD PMID:24690739 NCBI chr10:81,044,071...81,060,271
Ensembl chr10:81,044,075...81,060,181
JBrowse link
G Sh3pxd2a SH3 and PX domains 2A multiple interactions ISO [Disulfiram binds to Copper] which results in increased expression of SH3PXD2A mRNA CTD PMID:24690739 NCBI chr19:47,260,174...47,464,612
Ensembl chr19:47,260,174...47,464,401
JBrowse link
G Sik1 salt inducible kinase 1 multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of SIK1 mRNA CTD PMID:24690739 NCBI chr17:31,844,248...31,855,804
Ensembl chr17:31,844,250...31,855,804
JBrowse link
G Sirt1 sirtuin 1 multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of SIRT1 mRNA CTD PMID:24690739 NCBI chr10:63,319,005...63,339,035
Ensembl chr10:63,319,005...63,381,704
JBrowse link
G Sirt6 sirtuin 6 multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of SIRT6 mRNA CTD PMID:24690739 NCBI chr10:81,621,787...81,627,792
Ensembl chr10:81,621,785...81,627,797
JBrowse link
G Ski ski sarcoma viral oncogene homolog (avian) multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of SKI mRNA CTD PMID:24690739 NCBI chr 4:155,154,075...155,222,535
Ensembl chr 4:155,154,075...155,222,592
JBrowse link
G Skil SKI-like multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of SKIL mRNA CTD PMID:24690739 NCBI chr 3:31,095,058...31,122,923
Ensembl chr 3:31,095,058...31,122,577
JBrowse link
G Slc16a10 solute carrier family 16 (monocarboxylic acid transporters), member 10 multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of SLC16A10 mRNA CTD PMID:24690739 NCBI chr10:40,033,532...40,142,270
Ensembl chr10:40,033,532...40,142,258
JBrowse link
G Slc25a37 solute carrier family 25, member 37 multiple interactions ISO [Disulfiram binds to Copper] which results in increased expression of SLC25A37 mRNA CTD PMID:24690739 NCBI chr14:69,241,848...69,285,544
Ensembl chr14:69,241,848...69,285,112
JBrowse link
G Slc30a1 solute carrier family 30 (zinc transporter), member 1 multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of SLC30A1 mRNA CTD PMID:24690739 NCBI chr 1:191,906,697...191,913,248
Ensembl chr 1:191,906,767...191,913,247
JBrowse link
G Slc44a1 solute carrier family 44, member 1 multiple interactions ISO [Disulfiram binds to Copper] which results in increased expression of SLC44A1 mRNA CTD PMID:24690739 NCBI chr 4:53,440,387...53,622,478
Ensembl chr 4:53,440,413...53,622,478
JBrowse link
G Slc44a2 solute carrier family 44, member 2 multiple interactions ISO [Disulfiram binds to Copper] which results in increased expression of SLC44A2 mRNA CTD PMID:24690739 NCBI chr 9:21,320,719...21,355,028
Ensembl chr 9:21,320,698...21,355,028
JBrowse link
G Slc6a9 solute carrier family 6 (neurotransmitter transporter, glycine), member 9 multiple interactions ISO [Disulfiram binds to Copper] which results in increased expression of SLC6A9 mRNA CTD PMID:24690739 NCBI chr 4:117,835,258...117,869,305
Ensembl chr 4:117,834,506...117,875,198
JBrowse link
G Slc7a1 solute carrier family 7 (cationic amino acid transporter, y+ system), member 1 multiple interactions ISO [Disulfiram binds to Copper] which results in increased expression of SLC7A1 mRNA CTD PMID:24690739 NCBI chr 5:148,327,410...148,399,904
Ensembl chr 5:148,327,410...148,399,904
JBrowse link
G Slc7a6os solute carrier family 7, member 6 opposite strand multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of SLC7A6OS mRNA CTD PMID:24690739 NCBI chr 8:106,200,438...106,210,933
Ensembl chr 8:106,200,717...106,210,935
JBrowse link
G Slfn9 schlafen 9 multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of SLFN11 mRNA CTD PMID:24690739 NCBI chr11:82,974,316...82,991,830
Ensembl chr11:82,978,390...82,991,830
JBrowse link
G Slu7 SLU7 splicing factor homolog (S. cerevisiae) multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of SLU7 mRNA CTD PMID:24690739 NCBI chr11:43,433,726...43,447,982
Ensembl chr11:43,433,744...43,447,981
JBrowse link
G Smad3 SMAD family member 3 multiple interactions ISO [Disulfiram binds to Copper] which results in increased expression of SMAD3 mRNA CTD PMID:24690739 NCBI chr 9:63,646,766...63,757,994
Ensembl chr 9:63,646,767...63,757,994
JBrowse link
G Smox spermine oxidase multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of SMOX mRNA CTD PMID:24690739 NCBI chr 2:131,491,858...131,525,183
Ensembl chr 2:131,491,496...131,525,922
JBrowse link
G Snai1 snail family zinc finger 1 multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of SNAI1 mRNA CTD PMID:24690739 NCBI chr 2:167,538,195...167,542,814
Ensembl chr 2:167,538,195...167,542,814
JBrowse link
G Snip1 Smad nuclear interacting protein 1 multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of SNIP1 mRNA CTD PMID:24690739 NCBI chr 4:125,066,672...125,074,043
Ensembl chr 4:125,066,672...125,074,042
JBrowse link
G Snora70 small nucleolar RNA, H/ACA box 70 multiple interactions ISO [Disulfiram binds to Copper] which results in increased expression of SNORA70 mRNA CTD PMID:24690739 NCBI chr  X:74,272,492...74,272,620
Ensembl chr  X:74,272,484...74,272,620
JBrowse link
G Snrpb2 U2 small nuclear ribonucleoprotein B multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of SNRPB2 mRNA CTD PMID:24690739 NCBI chr 2:143,063,069...143,072,052
Ensembl chr 2:143,063,039...143,072,853
JBrowse link
G Sod1 superoxide dismutase 1, soluble increases expression
decreases activity
ISO
EXP
Disulfiram results in increased expression of SOD1 mRNA
Disulfiram results in decreased activity of SOD1 protein
CTD PMID:19016906 PMID:20566472 NCBI chr16:90,220,762...90,226,333
Ensembl chr16:90,220,754...90,226,329
JBrowse link
G Sod2 superoxide dismutase 2, mitochondrial increases expression
multiple interactions
ISO Disulfiram results in increased expression of SOD2 mRNA
[Disulfiram co-treated with Zinc Sulfate] results in increased expression of SOD2 mRNA
CTD PMID:20566472 PMID:32712770 NCBI chr17:13,007,839...13,018,119
Ensembl chr17:13,006,846...13,040,063
JBrowse link
G Sod3 superoxide dismutase 3, extracellular increases expression ISO Disulfiram results in increased expression of SOD3 mRNA CTD PMID:20566472 NCBI chr 5:52,363,804...52,369,738
Ensembl chr 5:52,363,791...52,371,418
JBrowse link
G Sox8 SRY (sex determining region Y)-box 8 multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of SOX8 mRNA CTD PMID:24690739 NCBI chr17:25,565,893...25,570,686
Ensembl chr17:25,565,892...25,570,686
JBrowse link
G Spata20 spermatogenesis associated 20 multiple interactions ISO [Disulfiram binds to Copper] which results in increased expression of SPATA20 mRNA CTD PMID:24690739 NCBI chr11:94,478,904...94,485,310
Ensembl chr11:94,478,904...94,486,179
JBrowse link
G Spire1 spire type actin nucleation factor 1 multiple interactions ISO [Disulfiram binds to Copper] which results in increased expression of SPIRE1 mRNA CTD PMID:24690739 NCBI chr18:67,488,209...67,612,810
Ensembl chr18:67,488,209...67,610,790
JBrowse link
G Spsb1 splA/ryanodine receptor domain and SOCS box containing 1 increases expression ISO Disulfiram results in increased expression of SPSB1 mRNA CTD PMID:20566472 NCBI chr 4:149,896,283...149,955,006
Ensembl chr 4:149,896,283...149,955,043
JBrowse link
G Sptbn1 spectrin beta, non-erythrocytic 1 multiple interactions ISO [Disulfiram binds to Copper] which results in increased expression of SPTBN1 mRNA CTD PMID:24690739 NCBI chr11:30,099,395...30,268,384
Ensembl chr11:30,099,395...30,268,175
JBrowse link
G Spty2d1 SPT2 chromatin protein domain containing 1 multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of SPTY2D1 mRNA CTD PMID:24690739 NCBI chr 7:46,990,396...47,008,414
Ensembl chr 7:46,990,396...47,008,411
JBrowse link
G Srebf1 sterol regulatory element binding transcription factor 1 multiple interactions ISO [Disulfiram binds to Copper] which results in increased expression of SREBF1 mRNA CTD PMID:24690739 NCBI chr11:60,199,084...60,224,186
Ensembl chr11:60,199,089...60,222,581
JBrowse link
G Srxn1 sulfiredoxin 1 homolog (S. cerevisiae) increases expression ISO Disulfiram results in increased expression of SRXN1 mRNA CTD PMID:20566472 NCBI chr 2:152,105,524...152,111,376
Ensembl chr 2:152,105,516...152,111,376
JBrowse link
G Ssxa1 synovial sarcoma, X member A1 multiple interactions ISO [Disulfiram binds to Copper] which results in increased expression of SSX3 mRNA CTD PMID:24690739 NCBI chr  X:21,118,414...21,122,088
Ensembl chr  X:21,115,820...21,121,192
JBrowse link
G Stc2 stanniocalcin 2 multiple interactions ISO [Disulfiram binds to Copper] which results in increased expression of STC2 mRNA CTD PMID:24690739 NCBI chr11:31,359,441...31,370,061
Ensembl chr11:31,357,307...31,370,074
JBrowse link
G Steep1 STING1 ER exit protein 1 multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of STEEP1 mRNA CTD PMID:24690739 NCBI chr  X:36,827,161...36,864,303
Ensembl chr  X:36,823,737...36,874,111
JBrowse link
G Stx3 syntaxin 3 multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of STX3 mRNA CTD PMID:24690739 NCBI chr19:11,775,118...11,821,569
Ensembl chr19:11,775,118...11,819,403
JBrowse link
G Sulf1 sulfatase 1 multiple interactions ISO
EXP
[Disulfiram binds to Copper] which results in increased expression of SULF1 mRNA; [Disulfiram binds to Copper] which results in increased expression of SULF1 protein CTD PMID:24690739 NCBI chr 1:12,692,197...12,861,192
Ensembl chr 1:12,692,277...12,861,192
JBrowse link
G Sumo2 small ubiquitin-like modifier 2 multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of SUMO2 mRNA CTD PMID:24690739 NCBI chr11:115,523,109...115,536,230
Ensembl chr11:115,523,102...115,536,276
JBrowse link
G Sun1 Sad1 and UNC84 domain containing 1 multiple interactions ISO [Disulfiram binds to Copper] which results in increased expression of SUN1 mRNA CTD PMID:24690739 NCBI chr 5:139,200,564...139,249,839
Ensembl chr 5:139,200,637...139,249,840
JBrowse link
G Sun2 Sad1 and UNC84 domain containing 2 multiple interactions ISO [Disulfiram binds to Copper] which results in increased expression of SUN2 mRNA CTD PMID:24690739 NCBI chr15:79,724,068...79,742,536
Ensembl chr15:79,724,070...79,742,536
JBrowse link
G Supt4a SPT4A, DSIF elongation factor subunit multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of SUPT4H1 mRNA CTD PMID:24690739 NCBI chr11:87,737,551...87,743,623
Ensembl chr11:87,737,552...87,743,623
JBrowse link
G Synj1 synaptojanin 1 multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of SYNJ1 mRNA CTD PMID:24690739 NCBI chr16:90,936,092...91,013,727
Ensembl chr16:90,936,092...91,011,308
JBrowse link
G Szrd1 SUZ RNA binding domain containing 1 multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of SZRD1 mRNA CTD PMID:24690739 NCBI chr 4:141,112,978...141,139,799
Ensembl chr 4:141,113,001...141,139,775
JBrowse link
G Taf13 TATA-box binding protein associated factor 13 multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of TAF13 mRNA CTD PMID:24690739 NCBI chr 3:108,571,699...108,582,068
Ensembl chr 3:108,571,698...108,583,222
JBrowse link
G Taf7 TATA-box binding protein associated factor 7 multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of TAF7 mRNA CTD PMID:24690739 NCBI chr18:37,640,491...37,644,204
Ensembl chr18:37,640,491...37,644,204
JBrowse link
G Tamalin trafficking regulator and scaffold protein tamalin multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of TAMALIN mRNA CTD PMID:24690739 NCBI chr15:101,224,207...101,232,756
Ensembl chr15:101,224,188...101,232,756
JBrowse link
G Tanc1 tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 1 multiple interactions ISO [Disulfiram binds to Copper] which results in increased expression of TANC1 mRNA CTD PMID:24690739 NCBI chr 2:59,611,821...59,846,213
Ensembl chr 2:59,612,042...59,846,149
JBrowse link
G Tap2 transporter 2, ATP-binding cassette, sub-family B (MDR/TAP) multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of TAP2 mRNA CTD PMID:24690739 NCBI chr17:34,204,479...34,216,321
Ensembl chr17:34,203,527...34,216,321
JBrowse link
G Tapbp TAP binding protein multiple interactions ISO [Disulfiram binds to Copper] which results in increased expression of TAPBP mRNA CTD PMID:24690739 NCBI chr17:33,919,478...33,929,290
Ensembl chr17:33,915,899...33,929,292
JBrowse link
G Tat tyrosine aminotransferase multiple interactions ISO [Ethanol co-treated with Disulfiram] results in increased activity of TAT protein CTD PMID:9591243 NCBI chr 8:109,986,078...109,999,804
Ensembl chr 8:109,990,437...109,999,803
JBrowse link
G Tcea2 transcription elongation factor A (SII), 2 multiple interactions ISO [Disulfiram binds to Copper] which results in increased expression of TCEA2 mRNA CTD PMID:24690739 NCBI chr 2:181,680,297...181,688,067
Ensembl chr 2:181,680,310...181,688,071
JBrowse link
G Tcp1 t-complex protein 1 multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of TCP1 mRNA CTD PMID:24690739 NCBI chr17:12,916,329...12,925,067
Ensembl chr17:12,915,701...12,925,067
JBrowse link
G Tent5b terminal nucleotidyltransferase 5B multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of TENT5B mRNA CTD PMID:24690739 NCBI chr 4:133,480,133...133,487,940
Ensembl chr 4:133,480,132...133,487,938
JBrowse link
G Tent5c terminal nucleotidyltransferase 5C multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of TENT5C mRNA CTD PMID:24690739 NCBI chr 3:100,468,057...100,489,192
Ensembl chr 3:100,451,628...100,489,324
JBrowse link
G Tfip11 tuftelin interacting protein 11 multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of TFIP11 mRNA CTD PMID:24690739 NCBI chr 5:112,326,369...112,338,073
Ensembl chr 5:112,326,358...112,338,073
JBrowse link
G Tgfb1 transforming growth factor, beta 1 decreases activity ISO Disulfiram results in decreased activity of TGFB1 protein CTD PMID:31652400 NCBI chr 7:25,687,002...25,705,077
Ensembl chr 7:25,687,002...25,705,077
JBrowse link
G Thap1 THAP domain containing, apoptosis associated protein 1 multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of THAP1 mRNA CTD PMID:24690739 NCBI chr 8:26,158,169...26,164,151
Ensembl chr 8:26,158,141...26,164,151
JBrowse link
G Them6 thioesterase superfamily member 6 multiple interactions ISO [Disulfiram binds to Copper] which results in increased expression of THEM6 mRNA CTD PMID:24690739 NCBI chr15:74,721,234...74,724,373
Ensembl chr15:74,721,204...74,724,639
JBrowse link
G Thra thyroid hormone receptor alpha multiple interactions ISO Disulfiram binds to and results in increased activity of THRA protein CTD PMID:33049310 NCBI chr11:98,740,776...98,769,006
Ensembl chr11:98,740,638...98,769,006
JBrowse link
G Ticam2 toll-like receptor adaptor molecule 2 multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of TICAM2 mRNA CTD PMID:24690739 NCBI chr18:46,558,231...46,574,533
Ensembl chr18:46,557,291...46,574,533
JBrowse link
G Tmem167 transmembrane protein 167 multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of TMEM167A mRNA CTD PMID:24690739 NCBI chr13:90,089,667...90,114,921
Ensembl chr13:90,089,123...90,143,907
JBrowse link
G Tmem175 transmembrane protein 175 multiple interactions ISO [Disulfiram binds to Copper] which results in increased expression of TMEM175 mRNA CTD PMID:24690739 NCBI chr 5:108,629,779...108,647,770
Ensembl chr 5:108,629,770...108,648,782
JBrowse link
G Tmem208 transmembrane protein 208 multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of TMEM208 mRNA CTD PMID:24690739 NCBI chr 8:105,326,341...105,335,485
Ensembl chr 8:105,326,354...105,335,219
JBrowse link
G Tmem35b transmembrane protein 35B multiple interactions ISO [Disulfiram binds to Copper] which results in increased expression of TMEM35B mRNA CTD PMID:24690739 NCBI chr 4:127,126,043...127,129,660
Ensembl chr 4:127,123,691...127,129,644
JBrowse link
G Tmem42 transmembrane protein 42 multiple interactions ISO [Disulfiram binds to Copper] which results in increased expression of TMEM42 mRNA CTD PMID:24690739 NCBI chr 9:123,021,007...123,023,491
Ensembl chr 9:123,021,326...123,023,705
JBrowse link
G Tmem43 transmembrane protein 43 multiple interactions ISO [Disulfiram binds to Copper] which results in increased expression of TMEM43 mRNA CTD PMID:24690739 NCBI chr 6:91,473,707...91,488,463
Ensembl chr 6:91,473,703...91,488,463
JBrowse link
G Tmem44 transmembrane protein 44 multiple interactions ISO [Disulfiram binds to Copper] which results in increased expression of TMEM44 mRNA CTD PMID:24690739 NCBI chr16:30,511,855...30,550,825
Ensembl chr16:30,511,855...30,550,842
JBrowse link
G Tnf tumor necrosis factor decreases expression
multiple interactions
increases secretion
ISO
EXP
Disulfiram results in decreased expression of TNF mRNA
[Disulfiram co-treated with Zinc Sulfate] inhibits the reaction [Lipopolysaccharides results in increased secretion of TNF protein]; Disulfiram promotes the reaction [Lipopolysaccharides results in increased secretion of TNF protein]
Disulfiram results in increased secretion of TNF protein
Disulfiram inhibits the reaction [[CCL5 protein binds to and results in increased activity of CCR5 protein] which results in increased secretion of TNF protein]
CTD PMID:10418820 PMID:19016906 PMID:32712770 NCBI chr17:35,199,367...35,202,007
Ensembl chr17:35,199,381...35,202,007
JBrowse link
G Tnip1 TNFAIP3 interacting protein 1 multiple interactions EXP
ISO
[Disulfiram binds to Copper] which results in increased expression of TNIP1 protein CTD PMID:24690739 NCBI chr11:54,910,787...54,962,956
Ensembl chr11:54,910,785...54,962,917
JBrowse link
G Tnip2 TNFAIP3 interacting protein 2 multiple interactions ISO [Disulfiram binds to Copper] which results in increased expression of TNIP2 protein CTD PMID:24690739 NCBI chr 5:34,496,096...34,513,979
Ensembl chr 5:34,496,087...34,513,991
JBrowse link
G Tns3 tensin 3 multiple interactions ISO [Disulfiram binds to Copper] which results in increased expression of TNS3 mRNA CTD PMID:24690739 NCBI chr11:8,431,652...8,664,758
Ensembl chr11:8,431,652...8,664,681
JBrowse link
G Tprkb Tp53rk binding protein multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of TPRKB mRNA CTD PMID:24690739 NCBI chr 6:85,911,860...85,930,284
Ensembl chr 6:85,911,865...85,930,284
JBrowse link
G Tpsab1 tryptase alpha/beta 1 multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of TPSAB1 mRNA CTD PMID:24690739 NCBI chr17:25,343,245...25,345,562
Ensembl chr17:25,343,245...25,345,562
JBrowse link
G Tra2b transformer 2 beta multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of TRA2B mRNA CTD PMID:24690739 NCBI chr16:22,244,552...22,266,005
Ensembl chr16:22,244,549...22,266,005
JBrowse link
G Trabd TraB domain containing multiple interactions ISO [Disulfiram binds to Copper] which results in increased expression of TRABD mRNA CTD PMID:24690739 NCBI chr15:89,076,064...89,087,075
Ensembl chr15:89,075,124...89,087,077
JBrowse link
G Trh thyrotropin releasing hormone multiple interactions
increases expression
decreases expression
ISO Dexamethasone promotes the reaction [Disulfiram results in decreased expression of TRH protein]
Disulfiram results in increased expression of TRH mRNA alternative form
CTD PMID:9681491 NCBI chr 6:92,242,061...92,244,650
Ensembl chr 6:92,242,061...92,244,650
JBrowse link
G Tshb thyroid stimulating hormone, beta subunit multiple interactions
decreases secretion
ISO Dexamethasone promotes the reaction [Disulfiram results in decreased secretion of TSHB protein] CTD PMID:9681491 NCBI chr 3:102,777,398...102,789,082
Ensembl chr 3:102,775,465...102,782,718
JBrowse link
G Tspyl2 TSPY-like 2 multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of TSPYL2 mRNA CTD PMID:24690739 NCBI chr  X:152,336,851...152,342,484
Ensembl chr  X:152,336,852...152,342,425
JBrowse link
G Ttc13 tetratricopeptide repeat domain 13 multiple interactions ISO [Disulfiram binds to Copper] which results in increased expression of TTC13 mRNA CTD PMID:24690739 NCBI chr 8:124,671,327...124,722,011
Ensembl chr 8:124,671,332...124,721,983
JBrowse link
G Ttf1 transcription termination factor, RNA polymerase I multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of TTF1 mRNA CTD PMID:24690739 NCBI chr 2:29,060,199...29,087,656
Ensembl chr 2:29,060,262...29,087,656
JBrowse link
G Tuba4a tubulin, alpha 4A multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of TUBA4A mRNA CTD PMID:24690739 NCBI chr 1:75,214,972...75,221,261
Ensembl chr 1:75,214,228...75,219,865
JBrowse link
G Tubb2a tubulin, beta 2A class IIA multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of TUBB2A mRNA CTD PMID:24690739 NCBI chr13:34,074,278...34,078,008
Ensembl chr13:34,074,274...34,078,007
JBrowse link
G Tubb2b tubulin, beta 2B class IIB multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of TUBB2B mRNA CTD PMID:24690739 NCBI chr13:34,127,008...34,130,354
Ensembl chr13:34,126,748...34,130,466
JBrowse link
G Tubb3 tubulin, beta 3 class III multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of TUBB3 mRNA CTD PMID:24690739 NCBI chr 8:123,411,553...123,422,015
Ensembl chr 8:123,411,424...123,422,015
JBrowse link
G Txn2 thioredoxin 2 increases expression ISO Disulfiram results in increased expression of TXN2 mRNA CTD PMID:20566472 NCBI chr15:77,915,051...77,928,994
Ensembl chr15:77,915,047...77,929,006
JBrowse link
G Txnl1 thioredoxin-like 1 multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of TXNL1 mRNA CTD PMID:24690739 NCBI chr18:63,662,801...63,692,359
Ensembl chr18:63,661,094...63,708,801
JBrowse link
G Txnrd1 thioredoxin reductase 1 increases expression ISO Disulfiram results in increased expression of TXNRD1 mRNA CTD PMID:20566472 NCBI chr10:82,833,951...82,897,724
Ensembl chr10:82,833,951...82,897,712
JBrowse link
G Txnrd2 thioredoxin reductase 2 increases expression ISO Disulfiram results in increased expression of TXNRD2 mRNA CTD PMID:20566472 NCBI chr16:18,426,417...18,479,073
Ensembl chr16:18,426,384...18,479,073
JBrowse link
G Ubfd1 ubiquitin family domain containing 1 multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of UBFD1 mRNA CTD PMID:24690739 NCBI chr 7:122,067,095...122,082,199
Ensembl chr 7:122,067,175...122,082,194
JBrowse link
G Ugt1a6b UDP glucuronosyltransferase 1 family, polypeptide A6B increases expression ISO Disulfiram results in increased expression of UGT1A6 mRNA CTD PMID:20566472 NCBI chr 1:88,103,257...88,218,998
Ensembl chr 1:88,103,252...88,219,003
JBrowse link
G Ulk1 unc-51 like kinase 1 multiple interactions ISO [Disulfiram binds to Copper] which results in increased expression of ULK1 mRNA CTD PMID:24690739 NCBI chr 5:110,784,489...110,810,120
Ensembl chr 5:110,784,488...110,810,097
JBrowse link
G Uqcrb ubiquinol-cytochrome c reductase binding protein multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of UQCRB mRNA CTD PMID:24690739 NCBI chr13:66,900,576...66,905,350
Ensembl chr13:66,900,617...66,905,378
JBrowse link
G Uqcrh ubiquinol-cytochrome c reductase hinge protein multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of UQCRH mRNA CTD PMID:24690739 NCBI chr 4:116,066,965...116,075,070
Ensembl chr 4:116,066,965...116,075,071
JBrowse link
G Uspl1 ubiquitin specific peptidase like 1 multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of USPL1 mRNA CTD PMID:24690739 NCBI chr 5:149,184,560...149,215,434
Ensembl chr 5:149,184,350...149,215,434
JBrowse link
G Utp11 UTP11 small subunit processome component multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of UTP11 mRNA CTD PMID:24690739 NCBI chr 4:124,678,232...124,693,610
Ensembl chr 4:124,678,160...124,693,600
JBrowse link
G Utp3 UTP3 small subunit processome component multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of UTP3 mRNA CTD PMID:24690739 NCBI chr 5:88,554,462...88,556,090
Ensembl chr 5:88,554,462...88,556,090
JBrowse link
G Vcan versican multiple interactions ISO [Disulfiram binds to Copper] which results in increased expression of VCAN mRNA CTD PMID:24690739 NCBI chr13:89,655,309...89,743,027
Ensembl chr13:89,655,312...89,742,509
JBrowse link
G Vcl vinculin multiple interactions ISO [Disulfiram binds to Copper] which results in increased expression of VCL mRNA CTD PMID:24690739 NCBI chr14:20,929,383...21,033,676
Ensembl chr14:20,929,398...21,033,676
JBrowse link
G Vdac1 voltage-dependent anion channel 1 multiple interactions ISO VDAC1 protein results in increased susceptibility to [arsenic trioxide co-treated with Ascorbic Acid co-treated with Disulfiram] CTD PMID:24126434 NCBI chr11:52,360,851...52,389,397
Ensembl chr11:52,360,860...52,389,397
JBrowse link
G Vegfc vascular endothelial growth factor C multiple interactions ISO [Disulfiram binds to Copper] which results in increased expression of VEGFC mRNA CTD PMID:24690739 NCBI chr 8:54,077,532...54,186,454
Ensembl chr 8:54,077,606...54,187,096
JBrowse link
G Vgf VGF nerve growth factor inducible multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of VGF mRNA CTD PMID:24690739 NCBI chr 5:137,025,301...137,033,351
Ensembl chr 5:137,026,392...137,033,351
JBrowse link
G Vim vimentin multiple interactions ISO
EXP
[Disulfiram binds to Copper] which results in increased cleavage of VIM protein CTD PMID:24690739 NCBI chr 2:13,574,311...13,582,826
Ensembl chr 2:13,573,927...13,582,826
JBrowse link
G Vps37b vacuolar protein sorting 37B multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of VPS37B mRNA CTD PMID:24690739 NCBI chr 5:124,004,641...124,032,260
Ensembl chr 5:124,004,641...124,032,270
JBrowse link
G Wdr20 WD repeat domain 20 multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of WDR20 mRNA CTD PMID:24690739 NCBI chr12:110,735,025...110,804,275
Ensembl chr12:110,737,944...110,804,238
JBrowse link
G Xylt2 xylosyltransferase II multiple interactions ISO [Disulfiram binds to Copper] which results in increased expression of XYLT2 mRNA CTD PMID:24690739 NCBI chr11:94,663,845...94,677,518
Ensembl chr11:94,663,851...94,677,515
JBrowse link
G Yju2 YJU2 splicing factor multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of YJU2 mRNA CTD PMID:24690739 NCBI chr17:55,959,187...55,967,951
Ensembl chr17:55,959,099...55,968,285
JBrowse link
G Zbtb43 zinc finger and BTB domain containing 43 multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of ZBTB43 mRNA CTD PMID:24690739 NCBI chr 2:33,450,287...33,468,581
Ensembl chr 2:33,450,287...33,468,559
JBrowse link
G Zfand2a zinc finger, AN1-type domain 2A multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of ZFAND2A mRNA CTD PMID:24690739 NCBI chr 5:139,471,216...139,484,491
Ensembl chr 5:139,471,211...139,484,549
JBrowse link
G Zfp105 zinc finger protein 105 multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of ZNF35 mRNA CTD PMID:24690739 NCBI chr 9:122,923,039...122,935,260
Ensembl chr 9:122,923,072...122,931,028
JBrowse link
G Zfp143 zinc finger protein 143 multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of ZNF143 mRNA CTD PMID:24690739 NCBI chr 7:110,061,689...110,095,396
Ensembl chr 7:110,061,217...110,095,394
JBrowse link
G Zfp217 zinc finger protein 217 multiple interactions ISO [Disulfiram binds to Copper] which results in increased expression of ZNF217 mRNA CTD PMID:24690739 NCBI chr 2:170,108,643...170,151,677
Ensembl chr 2:170,108,643...170,148,103
JBrowse link
G Zfp26 zinc finger protein 26 multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of ZNF778 mRNA CTD PMID:24690739 NCBI chr 9:20,428,318...20,460,169
Ensembl chr 9:20,428,449...20,460,162
JBrowse link
G Zfp36 zinc finger protein 36 multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of ZFP36 mRNA CTD PMID:24690739 NCBI chr 7:28,376,784...28,379,228
Ensembl chr 7:28,376,784...28,380,253
JBrowse link
G Zfp408 zinc finger protein 408 multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of ZNF408 mRNA CTD PMID:24690739 NCBI chr 2:91,642,756...91,650,051
Ensembl chr 2:91,643,669...91,649,791
JBrowse link
G Zfp622 zinc finger protein 622 multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of ZNF622 mRNA CTD PMID:24690739 NCBI chr15:25,984,366...25,998,482
Ensembl chr15:25,984,366...25,998,481
JBrowse link
G Zhx3 zinc fingers and homeoboxes 3 multiple interactions ISO [Disulfiram binds to Copper] which results in increased expression of ZHX3 mRNA CTD PMID:24690739 NCBI chr 2:160,770,447...160,872,990
Ensembl chr 2:160,748,708...160,872,998
JBrowse link
G Zkscan5 zinc finger with KRAB and SCAN domains 5 multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of ZKSCAN5 mRNA CTD PMID:24690739 NCBI chr 5:145,204,559...145,221,752
Ensembl chr 5:145,204,562...145,221,750
JBrowse link
G Zmat2 zinc finger, matrin type 2 multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of ZMAT2 mRNA CTD PMID:24690739 NCBI chr18:36,793,923...36,799,660
Ensembl chr18:36,793,876...36,799,666
JBrowse link
G Zmat5 zinc finger, matrin type 5 multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of ZMAT5 mRNA CTD PMID:24690739 NCBI chr11:4,704,656...4,737,669
Ensembl chr11:4,704,678...4,737,669
JBrowse link
G Zscan26 zinc finger and SCAN domain containing 26 multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of ZSCAN26 mRNA CTD PMID:24690739 NCBI chr13:21,442,180...21,453,727
Ensembl chr13:21,442,180...21,453,730
JBrowse link
metam term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Als2 alsin Rho guanine nucleotide exchange factor multiple interactions EXP methyldithiocarbamate affects the reaction [Lipopolysaccharides results in increased expression of ALS2 mRNA] CTD PMID:19339665 NCBI chr 1:59,162,756...59,237,231
Ensembl chr 1:59,162,926...59,237,231
JBrowse link
G C4bp complement component 4 binding protein multiple interactions EXP methyldithiocarbamate inhibits the reaction [Lipopolysaccharides results in increased expression of C4BP mRNA] CTD PMID:24056979 NCBI chr 1:130,635,921...130,661,657
Ensembl chr 1:130,634,773...130,661,632
JBrowse link
G Cat catalase multiple interactions EXP methyldithiocarbamate promotes the reaction [Lipopolysaccharides results in increased expression of CAT mRNA] CTD PMID:19339665 NCBI chr 2:103,453,904...103,485,153
Ensembl chr 2:103,453,849...103,485,160
JBrowse link
G Ccl11 chemokine (C-C motif) ligand 11 multiple interactions EXP methyldithiocarbamate inhibits the reaction [Poly I-C results in increased secretion of CCL11 protein] CTD PMID:24056979 NCBI chr11:82,057,832...82,062,955
Ensembl chr11:82,057,823...82,062,955
JBrowse link
G Ccl2 chemokine (C-C motif) ligand 2 multiple interactions EXP methyldithiocarbamate inhibits the reaction [Poly I-C results in increased secretion of CCL2 protein] CTD PMID:24056979 NCBI chr11:82,035,577...82,037,452
Ensembl chr11:82,035,571...82,037,453
JBrowse link
G Ccl3 chemokine (C-C motif) ligand 3 multiple interactions EXP methyldithiocarbamate inhibits the reaction [Lipopolysaccharides results in increased secretion of CCL3 protein] CTD PMID:19339665 PMID:24056979 NCBI chr11:83,647,843...83,649,378
Ensembl chr11:83,647,844...83,649,355
JBrowse link
G Ccl4 chemokine (C-C motif) ligand 4 multiple interactions EXP methyldithiocarbamate inhibits the reaction [Poly I-C results in increased secretion of CCL4 protein] CTD PMID:24056979 NCBI chr11:83,648,624...83,664,683
Ensembl chr11:83,662,584...83,664,683
JBrowse link
G Ccl5 chemokine (C-C motif) ligand 5 multiple interactions EXP methyldithiocarbamate inhibits the reaction [Poly I-C results in increased secretion of CCL5 protein] CTD PMID:24056979 NCBI chr11:83,525,778...83,530,518
Ensembl chr11:83,525,778...83,530,518
JBrowse link
G Cd40 CD40 antigen multiple interactions EXP methyldithiocarbamate inhibits the reaction [Lipopolysaccharides results in increased expression of CD40 mRNA] CTD PMID:24056979 NCBI chr 2:165,055,614...165,071,654
Ensembl chr 2:165,055,627...165,072,948
JBrowse link
G Cd55 CD55 molecule, decay accelerating factor for complement multiple interactions EXP methyldithiocarbamate inhibits the reaction [Lipopolysaccharides results in decreased expression of CD55 mRNA] CTD PMID:24056979 NCBI chr 1:130,429,798...130,465,009
Ensembl chr 1:130,439,027...130,462,744
JBrowse link
G Cfb complement factor B multiple interactions EXP methyldithiocarbamate inhibits the reaction [Lipopolysaccharides results in increased expression of CFB mRNA] CTD PMID:24056979 NCBI chr17:34,856,374...34,862,514
Ensembl chr17:34,856,374...34,862,518
JBrowse link
G Clec2h C-type lectin domain family 2, member h multiple interactions EXP methyldithiocarbamate inhibits the reaction [Lipopolysaccharides results in increased expression of CLEC2D mRNA] CTD PMID:24056979 NCBI chr 6:128,662,385...128,677,374
Ensembl chr 6:128,662,385...128,677,374
JBrowse link
G Clec7a C-type lectin domain family 7, member a multiple interactions EXP methyldithiocarbamate inhibits the reaction [Lipopolysaccharides results in decreased expression of CLEC7A mRNA] CTD PMID:24056979 NCBI chr 6:129,461,591...129,472,785
Ensembl chr 6:129,461,591...129,472,779
JBrowse link
G Crtam cytotoxic and regulatory T cell molecule multiple interactions EXP methyldithiocarbamate inhibits the reaction [Lipopolysaccharides results in decreased expression of CRTAM mRNA] CTD PMID:24056979 NCBI chr 9:40,972,798...41,004,628
Ensembl chr 9:40,969,691...41,004,628
JBrowse link
G Csf2 colony stimulating factor 2 (granulocyte-macrophage) multiple interactions EXP methyldithiocarbamate inhibits the reaction [Lipopolysaccharides results in increased expression of CSF2 mRNA]; methyldithiocarbamate inhibits the reaction [Lipopolysaccharides results in increased secretion of CSF2 protein] CTD PMID:19339665 PMID:24056979 NCBI chr11:54,247,270...54,249,899
Ensembl chr11:54,247,271...54,249,667
JBrowse link
G Ctsb cathepsin B multiple interactions EXP methyldithiocarbamate promotes the reaction [Lipopolysaccharides results in increased expression of CTSB mRNA] CTD PMID:19339665 NCBI chr14:63,122,462...63,145,923
Ensembl chr14:63,122,462...63,145,923
JBrowse link
G Cxcl9 chemokine (C-X-C motif) ligand 9 multiple interactions EXP methyldithiocarbamate inhibits the reaction [Lipopolysaccharides results in increased secretion of CXCL9 protein]; methyldithiocarbamate inhibits the reaction [Poly I-C results in increased secretion of CXCL9 protein] CTD PMID:16321413 PMID:24056979 NCBI chr 5:92,321,331...92,328,079
Ensembl chr 5:92,321,347...92,328,079
JBrowse link
G Ddx58 DEAD/H box helicase 58 multiple interactions EXP methyldithiocarbamate inhibits the reaction [Lipopolysaccharides results in increased expression of DDX58 mRNA] CTD PMID:24056979 NCBI chr 4:40,203,777...40,239,825
Ensembl chr 4:40,203,773...40,239,828
JBrowse link
G Dhx58 DEXH (Asp-Glu-X-His) box polypeptide 58 multiple interactions EXP methyldithiocarbamate inhibits the reaction [Lipopolysaccharides results in increased expression of DHX58 mRNA] CTD PMID:24056979 NCBI chr11:100,694,884...100,704,271
Ensembl chr11:100,694,884...100,704,271
JBrowse link
G Eif2ak2 eukaryotic translation initiation factor 2-alpha kinase 2 multiple interactions EXP methyldithiocarbamate inhibits the reaction [Lipopolysaccharides results in increased expression of EIF2AK2 mRNA] CTD PMID:24056979 NCBI chr17:78,850,504...78,882,572
Ensembl chr17:78,852,564...78,882,573
JBrowse link
G Ereg epiregulin multiple interactions EXP methyldithiocarbamate inhibits the reaction [Lipopolysaccharides results in decreased expression of EREG mRNA] CTD PMID:24056979 NCBI chr 5:91,074,617...91,093,649
Ensembl chr 5:91,074,622...91,093,646
JBrowse link
G Fcgr1 Fc receptor, IgG, high affinity I multiple interactions EXP methyldithiocarbamate inhibits the reaction [Lipopolysaccharides results in increased expression of FCGR1 mRNA] CTD PMID:24056979 NCBI chr 3:96,282,909...96,293,969
Ensembl chr 3:96,282,909...96,293,969
JBrowse link
G Gab1 growth factor receptor bound protein 2-associated protein 1 multiple interactions EXP methyldithiocarbamate promotes the reaction [Lipopolysaccharides results in increased expression of GAB1 mRNA] CTD PMID:19339665 NCBI chr 8:80,764,431...80,880,519
Ensembl chr 8:80,764,438...80,880,519
JBrowse link
G Gclm glutamate-cysteine ligase, modifier subunit multiple interactions EXP methyldithiocarbamate promotes the reaction [Lipopolysaccharides results in increased expression of GCLM mRNA] CTD PMID:19339665 NCBI chr 3:122,245,487...122,267,215
Ensembl chr 3:122,245,557...122,270,732
JBrowse link
G Gpx3 glutathione peroxidase 3 multiple interactions EXP methyldithiocarbamate inhibits the reaction [Lipopolysaccharides results in increased expression of GPX3 mRNA] CTD PMID:19339665 NCBI chr11:54,902,854...54,910,387
Ensembl chr11:54,902,453...54,910,377
JBrowse link
G Hif1a hypoxia inducible factor 1, alpha subunit multiple interactions EXP methyldithiocarbamate inhibits the reaction [Lipopolysaccharides results in increased expression of HIF1A mRNA] CTD PMID:19339665 NCBI chr12:73,901,324...73,947,554
Ensembl chr12:73,901,375...73,947,530
JBrowse link
G Idh1 isocitrate dehydrogenase 1 (NADP+), soluble multiple interactions EXP methyldithiocarbamate promotes the reaction [Lipopolysaccharides results in increased expression of IDH1 mRNA] CTD PMID:19339665 NCBI chr 1:65,158,616...65,186,479
Ensembl chr 1:65,158,616...65,186,500
JBrowse link
G Ifi202b interferon activated gene 202B multiple interactions EXP methyldithiocarbamate inhibits the reaction [Lipopolysaccharides affects the expression of IFI202B mRNA] CTD PMID:24056979 NCBI chr 1:173,962,569...173,982,844
Ensembl chr 1:173,962,568...173,982,744
JBrowse link
G Ifi203 interferon activated gene 203 multiple interactions EXP methyldithiocarbamate inhibits the reaction [Lipopolysaccharides affects the expression of IFI203 mRNA] CTD PMID:24056979 NCBI chr 1:173,920,400...173,942,866
Ensembl chr 1:173,920,407...173,942,672
JBrowse link
G Ifi204 interferon activated gene 204 multiple interactions EXP methyldithiocarbamate inhibits the reaction [Lipopolysaccharides affects the expression of IFI204 mRNA] CTD PMID:24056979 NCBI chr 1:173,747,293...173,767,069
Ensembl chr 1:173,747,293...173,766,943
JBrowse link
G Ifi205 interferon activated gene 205 multiple interactions EXP methyldithiocarbamate inhibits the reaction [Lipopolysaccharides affects the expression of IFI205 mRNA] CTD PMID:24056979 NCBI chr 1:174,011,998...174,031,755
Ensembl chr 1:174,011,998...174,031,810
JBrowse link
G Ifi47 interferon gamma inducible protein 47 multiple interactions EXP methyldithiocarbamate inhibits the reaction [Lipopolysaccharides affects the expression of IFI47 mRNA] CTD PMID:24056979 NCBI chr11:49,076,587...49,096,987
Ensembl chr11:49,076,587...49,096,974
JBrowse link
G Ifih1 interferon induced with helicase C domain 1 multiple interactions EXP methyldithiocarbamate inhibits the reaction [Lipopolysaccharides affects the expression of IFIH1 mRNA] CTD PMID:24056979 NCBI chr 2:62,595,618...62,646,255
Ensembl chr 2:62,595,798...62,646,255
JBrowse link
G Ifit1 interferon-induced protein with tetratricopeptide repeats 1 multiple interactions EXP methyldithiocarbamate inhibits the reaction [Lipopolysaccharides affects the expression of IFIT1 mRNA] CTD PMID:24056979 NCBI chr19:34,640,889...34,650,009
Ensembl chr19:34,640,871...34,650,009
JBrowse link
G Ifit2 interferon-induced protein with tetratricopeptide repeats 2 multiple interactions EXP methyldithiocarbamate inhibits the reaction [Lipopolysaccharides affects the expression of IFIT2 mRNA] CTD PMID:24056979 NCBI chr19:34,550,550...34,576,534
Ensembl chr19:34,550,694...34,576,419
JBrowse link
G Ifit3 interferon-induced protein with tetratricopeptide repeats 3 multiple interactions EXP methyldithiocarbamate inhibits the reaction [Lipopolysaccharides affects the expression of IFIT3 mRNA] CTD PMID:24056979 NCBI chr19:34,583,119...34,588,982
Ensembl chr19:34,583,531...34,588,731
JBrowse link
G Ifna2 interferon alpha 2 multiple interactions EXP methyldithiocarbamate inhibits the reaction [Lipopolysaccharides results in increased expression of IFNA2 mRNA] CTD PMID:24056979 NCBI chr 4:88,683,207...88,683,779
Ensembl chr 4:88,682,881...88,683,912
JBrowse link
G Ifna9 interferon alpha 9 multiple interactions EXP methyldithiocarbamate inhibits the reaction [Lipopolysaccharides results in increased expression of IFNA9 mRNA] CTD PMID:24056979 NCBI chr 4:88,591,813...88,592,385
Ensembl chr 4:88,591,813...88,592,385
JBrowse link
G Ifnb1 interferon beta 1, fibroblast multiple interactions EXP methyldithiocarbamate promotes the reaction [Lipopolysaccharides results in increased expression of IFNB1 mRNA] CTD PMID:24056979 NCBI chr 4:88,522,025...88,522,794
Ensembl chr 4:88,522,025...88,522,774
JBrowse link
G Ifng interferon gamma multiple interactions EXP methyldithiocarbamate inhibits the reaction [Lipopolysaccharides results in increased expression of IFNG mRNA]; methyldithiocarbamate inhibits the reaction [Lipopolysaccharides results in increased secretion of IFNG protein] CTD PMID:15933225 PMID:19339665 NCBI chr10:118,441,046...118,445,894
Ensembl chr10:118,441,046...118,445,892
JBrowse link
G Igtp interferon gamma induced GTPase multiple interactions EXP methyldithiocarbamate inhibits the reaction [Lipopolysaccharides affects the expression of IGTP mRNA] CTD PMID:24056979 NCBI chr11:58,199,556...58,207,592
Ensembl chr11:58,199,556...58,207,591
JBrowse link
G Iigp1 interferon inducible GTPase 1 multiple interactions EXP methyldithiocarbamate inhibits the reaction [Lipopolysaccharides affects the expression of IIGP1 mRNA] CTD PMID:24056979 NCBI chr18:60,373,616...60,392,634
Ensembl chr18:60,376,027...60,392,634
JBrowse link
G Il10 interleukin 10 multiple interactions EXP [Lipopolysaccharides co-treated with methyldithiocarbamate] results in increased expression of IL10 mRNA; [Lipopolysaccharides co-treated with methyldithiocarbamate] results in increased secretion of IL10 protein; [methyldithiocarbamate binds to Copper] promotes the reaction [Lipopolysaccharides results in increased secretion of IL10 protein]; [Nadolol co-treated with Mifepristone] promotes the reaction [methyldithiocarbamate promotes the reaction [Lipopolysaccharides results in increased secretion of IL10 protein]]; Buthionine Sulfoximine promotes the reaction [methyldithiocarbamate promotes the reaction [Lipopolysaccharides results in increased secretion of IL10 protein]]; methyldithiocarbamate promotes the reaction [Lipopolysaccharides results in increased expression of IL10 mRNA]; methyldithiocarbamate promotes the reaction [Lipopolysaccharides results in increased expression of IL10 protein]; methyldithiocarbamate promotes the reaction [Lipopolysaccharides results in increased secretion of IL10 protein] CTD PMID:15933225 PMID:16321413 PMID:19339665 PMID:24056979 NCBI chr 1:131,019,845...131,024,970
Ensembl chr 1:131,019,845...131,024,974
JBrowse link
G Il12a interleukin 12a multiple interactions EXP methyldithiocarbamate inhibits the reaction [Lipopolysaccharides results in increased expression of IL12A mRNA] CTD PMID:15933225 NCBI chr 3:68,690,644...68,698,550
Ensembl chr 3:68,690,644...68,698,547
JBrowse link
G Il12b interleukin 12b multiple interactions EXP [Nadolol co-treated with Mifepristone] inhibits the reaction [methyldithiocarbamate inhibits the reaction [Lipopolysaccharides results in increased secretion of IL12B protein]]; Buthionine Sulfoximine inhibits the reaction [methyldithiocarbamate inhibits the reaction [Lipopolysaccharides results in increased secretion of IL12B protein]]; methyldithiocarbamate inhibits the reaction [Lipopolysaccharides results in increased expression of IL12B mRNA]; methyldithiocarbamate inhibits the reaction [Lipopolysaccharides results in increased expression of IL12B protein]; methyldithiocarbamate inhibits the reaction [Lipopolysaccharides results in increased secretion of IL12B protein] CTD PMID:15933225 PMID:16321413 PMID:19339665 PMID:24056979 NCBI chr11:44,400,063...44,414,677
Ensembl chr11:44,400,063...44,414,033
JBrowse link
G Il18 interleukin 18 multiple interactions EXP methyldithiocarbamate inhibits the reaction [Lipopolysaccharides results in increased expression of IL18 mRNA] CTD PMID:15933225 NCBI chr 9:50,554,700...50,581,841
Ensembl chr 9:50,554,827...50,581,840
JBrowse link
G Il1a interleukin 1 alpha multiple interactions EXP methyldithiocarbamate inhibits the reaction [Lipopolysaccharides results in increased expression of IL1A mRNA] CTD PMID:15933225 NCBI chr 2:129,299,609...129,310,186
Ensembl chr 2:129,299,610...129,309,972
JBrowse link
G Il1b interleukin 1 beta multiple interactions EXP methyldithiocarbamate inhibits the reaction [Lipopolysaccharides results in increased expression of IL1B mRNA]; methyldithiocarbamate inhibits the reaction [Lipopolysaccharides results in increased secretion of IL1B protein] CTD PMID:15933225 PMID:19339665 PMID:24056979 NCBI chr 2:129,364,569...129,371,164
Ensembl chr 2:129,364,570...129,371,139
JBrowse link
G Il6 interleukin 6 multiple interactions EXP Buthionine Sulfoximine inhibits the reaction [methyldithiocarbamate inhibits the reaction [Lipopolysaccharides results in increased secretion of IL6 protein]]; methyldithiocarbamate inhibits the reaction [Lipopolysaccharides results in increased secretion of IL6 protein] CTD PMID:19339665 NCBI chr 5:30,013,114...30,019,975
Ensembl chr 5:30,013,114...30,019,981
JBrowse link
G Irf3 interferon regulatory factor 3 multiple interactions EXP methyldithiocarbamate inhibits the reaction [Lipopolysaccharides results in increased expression of IRF3 mRNA] CTD PMID:24056979 NCBI chr 7:44,997,648...45,002,848
Ensembl chr 7:44,997,648...45,002,848
JBrowse link
G Irf4 interferon regulatory factor 4 multiple interactions EXP methyldithiocarbamate inhibits the reaction [Lipopolysaccharides affects the expression of IRF4 mRNA] CTD PMID:24056979 NCBI chr13:30,749,233...30,766,981
Ensembl chr13:30,749,226...30,766,976
JBrowse link
G Irf5 interferon regulatory factor 5 multiple interactions EXP methyldithiocarbamate inhibits the reaction [Lipopolysaccharides affects the expression of IRF5 mRNA] CTD PMID:24056979 NCBI chr 6:29,526,130...29,541,869
Ensembl chr 6:29,526,625...29,541,871
JBrowse link
G Irf7 interferon regulatory factor 7 multiple interactions EXP methyldithiocarbamate inhibits the reaction [Lipopolysaccharides results in increased expression of IRF7 mRNA] CTD PMID:24056979 NCBI chr 7:141,263,183...141,266,499
Ensembl chr 7:141,262,706...141,266,481
JBrowse link
G Irgm1 immunity-related GTPase family M member 1 multiple interactions EXP methyldithiocarbamate inhibits the reaction [Lipopolysaccharides results in increased expression of IRGM1 mRNA] CTD PMID:24056979 NCBI chr11:48,865,245...48,871,420
Ensembl chr11:48,861,968...48,871,683
JBrowse link
G Irgm2 immunity-related GTPase family M member 2 multiple interactions EXP methyldithiocarbamate inhibits the reaction [Lipopolysaccharides affects the expression of IRGM2 mRNA] CTD PMID:24056979 NCBI chr11:58,214,977...58,222,783
Ensembl chr11:58,199,618...58,222,782
JBrowse link
G Isg15 ISG15 ubiquitin-like modifier multiple interactions EXP methyldithiocarbamate inhibits the reaction [Lipopolysaccharides results in increased expression of ISG15 mRNA] CTD PMID:24056979 NCBI chr 4:156,199,424...156,200,818
Ensembl chr 4:156,199,455...156,200,796
JBrowse link
G Klrk1 killer cell lectin-like receptor subfamily K, member 1 multiple interactions EXP methyldithiocarbamate inhibits the reaction [Lipopolysaccharides results in increased expression of KLRK1 mRNA] CTD PMID:24056979 NCBI chr 6:129,610,323...129,623,903
Ensembl chr 6:129,610,323...129,623,864
JBrowse link
G Malt1 MALT1 paracaspase multiple interactions EXP methyldithiocarbamate inhibits the reaction [Lipopolysaccharides results in increased expression of MALT1 mRNA] CTD PMID:24056979 NCBI chr18:65,430,939...65,478,888
Ensembl chr18:65,430,938...65,479,067
JBrowse link
G Mapk1 mitogen-activated protein kinase 1 multiple interactions EXP methyldithiocarbamate inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of MAPK1 protein] CTD PMID:15933225 NCBI chr16:16,983,382...17,047,453
Ensembl chr16:16,983,382...17,047,453
JBrowse link
G Mapk14 mitogen-activated protein kinase 14 multiple interactions EXP methyldithiocarbamate inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of MAPK14 protein] CTD PMID:15933225 NCBI chr17:28,691,342...28,748,405
Ensembl chr17:28,691,329...28,748,406
JBrowse link
G Mapk3 mitogen-activated protein kinase 3 multiple interactions EXP methyldithiocarbamate inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of MAPK3 protein] CTD PMID:15933225 NCBI chr 7:126,759,626...126,765,816
Ensembl chr 7:126,759,601...126,765,819
JBrowse link
G Mapk8 mitogen-activated protein kinase 8 multiple interactions EXP methyldithiocarbamate inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of MAPK8 protein] CTD PMID:15933225 NCBI chr14:33,377,898...33,447,353
Ensembl chr14:33,377,898...33,447,158
JBrowse link
G Masp1 mannan-binding lectin serine peptidase 1 multiple interactions EXP methyldithiocarbamate inhibits the reaction [Lipopolysaccharides results in decreased expression of MASP1 mRNA] CTD PMID:24056979 NCBI chr16:23,451,785...23,521,240
Ensembl chr16:23,449,417...23,520,815
JBrowse link
G Mbl2 mannose-binding lectin (protein C) 2 multiple interactions EXP methyldithiocarbamate inhibits the reaction [Lipopolysaccharides results in increased expression of MBL2 mRNA] CTD PMID:24056979 NCBI chr19:30,232,906...30,239,687
Ensembl chr19:30,232,942...30,239,687
JBrowse link
G Mif macrophage migration inhibitory factor (glycosylation-inhibiting factor) multiple interactions EXP methyldithiocarbamate inhibits the reaction [Lipopolysaccharides results in increased expression of MIF mRNA] CTD PMID:15933225 NCBI chr10:75,859,353...75,860,277
Ensembl chr10:75,859,353...75,860,240
JBrowse link
G Mtf1 metal response element binding transcription factor 1 multiple interactions EXP methyldithiocarbamate inhibits the reaction [Lipopolysaccharides results in increased expression of MTF1 mRNA] CTD PMID:19339665 NCBI chr 4:124,802,549...124,849,800
Ensembl chr 4:124,802,104...124,849,800
JBrowse link
G Mx1 MX dynamin-like GTPase 1 multiple interactions EXP methyldithiocarbamate inhibits the reaction [Lipopolysaccharides results in increased expression of MX1 mRNA] CTD PMID:24056979 NCBI chr16:97,447,035...97,462,906
Ensembl chr16:97,447,035...97,462,907
JBrowse link
G Mx2 MX dynamin-like GTPase 2 multiple interactions EXP methyldithiocarbamate inhibits the reaction [Lipopolysaccharides results in increased expression of MX2 mRNA] CTD PMID:24056979 NCBI chr16:97,536,081...97,560,901
Ensembl chr16:97,535,308...97,560,900
JBrowse link
G Myd88 myeloid differentiation primary response gene 88 multiple interactions EXP methyldithiocarbamate inhibits the reaction [Lipopolysaccharides results in increased expression of MYD88 mRNA] CTD PMID:24056979 NCBI chr 9:119,335,934...119,340,018
Ensembl chr 9:119,335,934...119,341,411
JBrowse link
G Myo1f myosin IF multiple interactions EXP methyldithiocarbamate inhibits the reaction [Lipopolysaccharides results in decreased expression of MYO1F mRNA] CTD PMID:24056979 NCBI chr17:33,555,707...33,607,764
Ensembl chr17:33,555,707...33,607,764
JBrowse link
G Nfkb1 nuclear factor of kappa light polypeptide gene enhancer in B cells 1, p105 multiple interactions EXP methyldithiocarbamate inhibits the reaction [Lipopolysaccharides results in increased expression of NFKB1 mRNA] CTD PMID:24056979 NCBI chr 3:135,584,655...135,691,969
Ensembl chr 3:135,584,655...135,691,547
JBrowse link
G Nod1 nucleotide-binding oligomerization domain containing 1 multiple interactions EXP methyldithiocarbamate inhibits the reaction [Lipopolysaccharides results in increased expression of NOD1 mRNA] CTD PMID:24056979 NCBI chr 6:54,923,942...54,972,674
Ensembl chr 6:54,923,949...54,972,612
JBrowse link
G Oas1a 2'-5' oligoadenylate synthetase 1A multiple interactions EXP methyldithiocarbamate inhibits the reaction [Lipopolysaccharides results in increased expression of OAS1A mRNA] CTD PMID:24056979 NCBI chr 5:120,896,256...120,907,544
Ensembl chr 5:120,896,256...120,907,521
JBrowse link
G Ppp1r15b protein phosphatase 1, regulatory subunit 15B multiple interactions EXP methyldithiocarbamate promotes the reaction [Lipopolysaccharides results in increased expression of PPP1R15B mRNA] CTD PMID:19339665 NCBI chr 1:133,131,166...133,139,800
Ensembl chr 1:133,131,143...133,139,783
JBrowse link
G Prdx1 peroxiredoxin 1 multiple interactions EXP methyldithiocarbamate promotes the reaction [Lipopolysaccharides results in increased expression of PRDX1 mRNA] CTD PMID:19339665 NCBI chr 4:116,685,599...116,700,000
Ensembl chr 4:116,685,544...116,700,822
JBrowse link
G Prnp prion protein multiple interactions EXP methyldithiocarbamate inhibits the reaction [Lipopolysaccharides results in increased expression of PRNP mRNA] CTD PMID:19339665 NCBI chr 2:131,909,928...131,938,436
Ensembl chr 2:131,909,928...131,938,429
JBrowse link
G Psmb5 proteasome (prosome, macropain) subunit, beta type 5 multiple interactions EXP methyldithiocarbamate inhibits the reaction [Lipopolysaccharides results in increased expression of PSMB5 mRNA] CTD PMID:19339665 NCBI chr14:54,614,120...54,617,995
Ensembl chr14:54,614,119...54,618,022
JBrowse link
G Ripk2 receptor (TNFRSF)-interacting serine-threonine kinase 2 multiple interactions EXP methyldithiocarbamate inhibits the reaction [Lipopolysaccharides results in increased expression of RIPK2 mRNA] CTD PMID:24056979 NCBI chr 4:16,122,732...16,163,678
Ensembl chr 4:16,122,733...16,163,647
JBrowse link
G Sod2 superoxide dismutase 2, mitochondrial multiple interactions EXP methyldithiocarbamate inhibits the reaction [Lipopolysaccharides results in increased expression of SOD2 mRNA] CTD PMID:19339665 NCBI chr17:13,007,839...13,018,119
Ensembl chr17:13,006,846...13,040,063
JBrowse link
G Srxn1 sulfiredoxin 1 homolog (S. cerevisiae) multiple interactions EXP methyldithiocarbamate promotes the reaction [Lipopolysaccharides results in increased expression of SRXN1 mRNA] CTD PMID:19339665 NCBI chr 2:152,105,524...152,111,376
Ensembl chr 2:152,105,516...152,111,376
JBrowse link
G Stat1 signal transducer and activator of transcription 1 multiple interactions EXP methyldithiocarbamate inhibits the reaction [Lipopolysaccharides results in increased expression of STAT1 mRNA] CTD PMID:24056979 NCBI chr 1:52,119,438...52,161,865
Ensembl chr 1:52,119,440...52,161,865
JBrowse link
G Stat5a signal transducer and activator of transcription 5A multiple interactions EXP methyldithiocarbamate inhibits the reaction [Lipopolysaccharides results in increased expression of STAT5A mRNA] CTD PMID:24056979 NCBI chr11:100,859,351...100,885,169
Ensembl chr11:100,859,351...100,885,169
JBrowse link
G Tirap toll-interleukin 1 receptor (TIR) domain-containing adaptor protein multiple interactions EXP methyldithiocarbamate inhibits the reaction [Lipopolysaccharides results in increased expression of TIRAP mRNA] CTD PMID:24056979 NCBI chr 9:35,184,391...35,200,291
Ensembl chr 9:35,184,551...35,200,291
JBrowse link
G Tlr3 toll-like receptor 3 multiple interactions EXP methyldithiocarbamate inhibits the reaction [Lipopolysaccharides results in increased expression of TLR3 mRNA] CTD PMID:24056979 NCBI chr 8:45,395,665...45,411,075
Ensembl chr 8:45,395,665...45,411,080
JBrowse link
G Tnf tumor necrosis factor multiple interactions EXP methyldithiocarbamate inhibits the reaction [Lipopolysaccharides results in increased secretion of TNF protein] CTD PMID:19339665 NCBI chr17:35,199,367...35,202,007
Ensembl chr17:35,199,381...35,202,007
JBrowse link
G Tor1aip2 torsin A interacting protein 2 multiple interactions EXP methyldithiocarbamate inhibits the reaction [Lipopolysaccharides affects the expression of TOR1AIP2 mRNA] CTD PMID:24056979 NCBI chr 1:156,035,664...156,068,861
Ensembl chr 1:156,035,403...156,068,861
JBrowse link
G Txnrd2 thioredoxin reductase 2 multiple interactions EXP methyldithiocarbamate promotes the reaction [Lipopolysaccharides results in increased expression of TXNRD2 mRNA] CTD PMID:19339665 NCBI chr16:18,426,417...18,479,073
Ensembl chr16:18,426,384...18,479,073
JBrowse link
G Uba1 ubiquitin-like modifier activating enzyme 1 multiple interactions ISO methyldithiocarbamate results in increased activity of and results in increased ubiquitination of UBA1 protein CTD PMID:25714994 NCBI chr  X:20,658,302...20,683,179
Ensembl chr  X:20,658,326...20,683,179
JBrowse link
G Xpa xeroderma pigmentosum, complementation group A multiple interactions EXP methyldithiocarbamate promotes the reaction [Lipopolysaccharides results in increased expression of XPA mRNA] CTD PMID:19339665 NCBI chr 4:46,175,220...46,196,344
Ensembl chr 4:46,155,347...46,196,311
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 21811
    role 21791
      application 21299
        pesticide 17498
          organosulfur pesticide 652
            dipymetitrone 0
            organosulfur acaricide + 585
            organosulfur insecticide + 89
            thiourea pesticide + 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 21811
    subatomic particle 21797
      composite particle 21797
        hadron 21797
          baryon 21797
            nucleon 21797
              atomic nucleus 21797
                atom 21797
                  main group element atom 21716
                    p-block element atom 21716
                      carbon group element atom 21530
                        carbon atom 21428
                          organic molecular entity 21428
                            heteroorganic entity 21111
                              organochalcogen compound 20438
                                organosulfur compound 15857
                                  organosulfur pesticide 652
                                    dipymetitrone 0
                                    organosulfur acaricide + 585
                                    organosulfur insecticide + 89
                                    thiourea pesticide + 0
paths to the root