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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:thiacloprid
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Accession:CHEBI:39175 term browser browse the term
Definition:A nitrile that is cyanamide in which the hydrogens are replaced by a 1,3-thiazolidin-2-ylidene group which in turn is substituted by a (6-chloropyridin-3-yl)methyl group at the ring nitrogen.
Synonyms:exact_synonym: {3-[(6-chloropyridin-3-yl)methyl]-1,3-thiazolidin-2-ylidene}cyanamide
 related_synonym: (3-((6-chloro-3-pyridinyl)methyl)-2-thiazolidinylidene)cyanamide;   Calypso;   Formula=C10H9ClN4S;   InChI=1S/C10H9ClN4S/c11-9-2-1-8(5-13-9)6-15-3-4-16-10(15)14-7-12/h1-2,5H,3-4,6H2;   InChIKey=HOKKPVIRMVDYPB-UHFFFAOYSA-N;   SMILES=Clc1ccc(CN2CCSC2=NC#N)cn1
 alt_id: CHEBI:90201
 xref: Beilstein:8553379;   CAS:111988-49-9;   KEGG:C18512
 xref_mesh: MESH:C417209
 xref: PDBeChem:TH4;   PMID:19937322;   PMID:22677783;   Patent:CN103404532;   Patent:PT1715743;   Reaxys:8553379


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thiacloprid term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcc2 ATP-binding cassette, sub-family member 2 multiple interactions EXP [Dietary Fats co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Captan co-treated with Chlorpyrifos co-treated with thiacloprid co-treated with Thiophanate co-treated with Ziram] results in increased expression of ABCC2 mRNA CTD PMID:32745781 NCBI chr19:43,770,747...43,826,771
Ensembl chr19:43,770,631...43,829,179 		JBrowse link
G Abcc3 ATP-binding cassette, sub-family C member 3 multiple interactions
increases expression		 EXP
ISO		 [Dietary Fats co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Captan co-treated with Chlorpyrifos co-treated with thiacloprid co-treated with Thiophanate co-treated with Ziram] results in increased expression of ABCC3 mRNA
thiacloprid results in increased expression of ABCC3 mRNA
[thiacloprid co-treated with clothianidin] results in increased expression of ABCC3 mRNA; [thiacloprid co-treated with enilconazole] results in increased expression of ABCC3 mRNA		 CTD PMID:32745781 PMID:33426623 NCBI chr11:94,234,121...94,283,843
Ensembl chr11:94,234,121...94,283,823 		JBrowse link
G Ache acetylcholinesterase decreases activity ISO thiacloprid results in decreased activity of ACHE protein CTD PMID:21251949 NCBI chr 5:137,286,516...137,292,728
Ensembl chr 5:137,285,781...137,292,728 		JBrowse link
G Acox1 acyl-Coenzyme A oxidase 1, palmitoyl multiple interactions EXP [Ziram co-treated with Thiophanate co-treated with Captan co-treated with Chlorpyrifos co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with thiacloprid] results in increased expression of ACOX1 mRNA CTD PMID:32736067 NCBI chr11:116,062,714...116,089,605
Ensembl chr11:116,062,714...116,089,871 		JBrowse link
G Alb albumin decreases expression
multiple interactions		 ISO thiacloprid results in decreased expression of ALB protein
astaxanthine inhibits the reaction [thiacloprid results in decreased expression of ALB protein]		 CTD PMID:34564187 NCBI chr 5:90,608,729...90,624,461
Ensembl chr 5:90,608,756...90,624,461 		JBrowse link
G Aldh1a1 aldehyde dehydrogenase family 1, subfamily A1 multiple interactions
increases expression		 ISO [thiacloprid co-treated with enilconazole] results in decreased expression of ALDH1A1 mRNA
thiacloprid results in increased expression of ALDH1A1 mRNA
[thiacloprid co-treated with clothianidin] results in increased expression of ALDH1A1 mRNA; [thiacloprid co-treated with enilconazole] results in increased expression of ALDH1A1 mRNA		 CTD PMID:32201337 PMID:33426623 NCBI chr19:20,469,947...20,620,827
Ensembl chr19:20,470,079...20,620,829 		JBrowse link
G Atg5 autophagy related 5 decreases expression EXP thiacloprid results in decreased expression of ATG5 mRNA; thiacloprid results in decreased expression of ATG5 protein CTD PMID:37468076 NCBI chr10:44,144,325...44,240,295
Ensembl chr10:44,144,354...44,240,287 		JBrowse link
G Cat catalase multiple interactions
decreases activity
decreases expression		 ISO astaxanthine inhibits the reaction [thiacloprid results in decreased activity of CAT protein]; Polysaccharides inhibits the reaction [thiacloprid results in decreased activity of CAT protein]; Polysaccharides inhibits the reaction [thiacloprid results in decreased expression of CAT mRNA] CTD PMID:28692354 PMID:34564187 NCBI chr 2:103,284,249...103,315,498
Ensembl chr 2:103,284,194...103,315,505 		JBrowse link
G Cd36 CD36 molecule multiple interactions EXP [Ziram co-treated with Thiophanate co-treated with Captan co-treated with Chlorpyrifos co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with thiacloprid] results in increased expression of CD36 mRNA CTD PMID:32736067 NCBI chr 5:17,986,680...18,093,828
Ensembl chr 5:17,986,688...18,093,799 		JBrowse link
G Ces2h carboxylesterase 2H multiple interactions ISO [clothianidin co-treated with thiacloprid] results in increased expression of CES2 protein; [enilconazole co-treated with thiacloprid] results in increased expression of CES2 protein CTD PMID:32201337 NCBI chr 8:105,727,462...105,747,042
Ensembl chr 8:105,727,485...105,747,810 		JBrowse link
G Chrnb2 cholinergic receptor nicotinic beta 2 subunit multiple interactions ISO thiacloprid results in increased activity of [NACHRA1 protein co-treated with CHRNB2 protein]; thiacloprid results in increased activity of [NACHRA8 protein co-treated with CHRNB2 protein] CTD PMID:16981889 PMID:25459289 NCBI chr 3:89,660,755...89,671,939
Ensembl chr 3:89,653,502...89,671,939 		JBrowse link
G Cpt1a carnitine palmitoyltransferase 1a, liver multiple interactions EXP [Ziram co-treated with Thiophanate co-treated with Captan co-treated with Chlorpyrifos co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with thiacloprid] results in increased expression of CPT1A mRNA CTD PMID:32736067 NCBI chr19:3,372,328...3,435,735
Ensembl chr19:3,372,334...3,435,733 		JBrowse link
G Crem cAMP responsive element modulator decreases expression EXP thiacloprid results in decreased expression of CREM mRNA; thiacloprid results in decreased expression of CREM protein CTD PMID:37468076 NCBI chr18:3,263,181...3,337,688
Ensembl chr18:3,266,048...3,337,748 		JBrowse link
G Cybb cytochrome b-245, beta polypeptide increases expression ISO thiacloprid results in increased expression of CYBB mRNA CTD PMID:32201337 NCBI chr  X:9,301,493...9,354,005
Ensembl chr  X:9,301,491...9,354,010 		JBrowse link
G Cyp11a1 cytochrome P450, family 11, subfamily a, polypeptide 1 decreases expression EXP thiacloprid results in decreased expression of CYP11A1 mRNA CTD PMID:37468076 NCBI chr 9:57,905,307...57,934,314
Ensembl chr 9:57,913,694...57,934,306 		JBrowse link
G Cyp19a1 cytochrome P450, family 19, subfamily a, polypeptide 1 increases activity
increases expression
multiple interactions
affects expression		 ISO thiacloprid results in increased activity of CYP19A1 protein
thiacloprid results in increased expression of CYP19A1 mRNA
1-(6-((3-methoxyestra-1,3,5(10)-trien-17-yl)amino)hexyl)-1H-pyrrole-2,5-dione affects the reaction [thiacloprid affects the expression of CYP19A1 mRNA]; 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one affects the reaction [thiacloprid affects the expression of CYP19A1 mRNA]		 CTD PMID:26464060 PMID:28750898 PMID:29701941 NCBI chr 9:54,073,221...54,175,448
Ensembl chr 9:54,073,221...54,175,394 		JBrowse link
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 increases expression ISO thiacloprid results in increased expression of CYP1A1 mRNA; thiacloprid results in increased expression of CYP1A1 protein CTD PMID:21784029 NCBI chr 9:57,595,211...57,611,107
Ensembl chr 9:57,595,211...57,611,107 		JBrowse link
G Cyp1a2 cytochrome P450, family 1, subfamily a, polypeptide 2 increases expression
multiple interactions		 ISO thiacloprid results in increased expression of CYP1A2 mRNA; thiacloprid results in increased expression of CYP1A2 protein
[enilconazole co-treated with thiacloprid co-treated with clothianidin] results in increased expression of CYP1A2 mRNA; [thiacloprid co-treated with enilconazole] results in increased expression of CYP1A2 mRNA		 CTD PMID:21784029 PMID:32201337 NCBI chr 9:57,584,220...57,590,938
Ensembl chr 9:57,584,220...57,590,986 		JBrowse link
G Cyp2a5 cytochrome P450, family 2, subfamily a, polypeptide 5 decreases expression
multiple interactions
increases expression		 ISO thiacloprid results in decreased expression of CYP2A6 protein
[clothianidin co-treated with thiacloprid] results in increased expression of CYP2A6 protein; [enilconazole co-treated with thiacloprid] results in decreased expression of CYP2A6 protein
thiacloprid results in increased expression of CYP2A6 mRNA		 CTD PMID:32201337 NCBI chr 7:26,534,764...26,542,689
Ensembl chr 7:26,534,730...26,542,973 		JBrowse link
G Cyp2b10 cytochrome P450, family 2, subfamily b, polypeptide 10 increases expression
multiple interactions		 ISO
EXP		 thiacloprid results in increased expression of CYP2B6 mRNA
[clothianidin co-treated with thiacloprid] results in increased expression of CYP2B6 protein; [enilconazole co-treated with thiacloprid] results in increased expression of CYP2B6 protein; [enilconazole co-treated with thiacloprid] results in increased expression of CYP2B9 protein; [thiacloprid co-treated with enilconazole] results in increased expression of CYP2B6 mRNA
[Dietary Fats co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Captan co-treated with Chlorpyrifos co-treated with thiacloprid co-treated with Thiophanate co-treated with Ziram] results in increased expression of CYP2B10 mRNA; [Ziram co-treated with Thiophanate co-treated with Captan co-treated with Chlorpyrifos co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with thiacloprid] results in increased expression of CYP2B10 mRNA		 CTD PMID:32201337 PMID:32736067 PMID:32745781 NCBI chr 7:25,597,083...25,626,049
Ensembl chr 7:25,597,045...25,626,049 		JBrowse link
G Cyp2b13 cytochrome P450, family 2, subfamily b, polypeptide 13 multiple interactions
increases expression		 ISO [thiacloprid co-treated with clothianidin] results in increased expression of CYP2B2 mRNA; [thiacloprid co-treated with enilconazole] results in increased expression of CYP2B2 mRNA
thiacloprid results in increased expression of CYP2B2 mRNA		 CTD PMID:33426623 NCBI chr 7:25,760,813...25,795,622
Ensembl chr 7:25,760,922...25,795,622 		JBrowse link
G Cyp2b9 cytochrome P450, family 2, subfamily b, polypeptide 9 multiple interactions EXP [Dietary Fats co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Captan co-treated with Chlorpyrifos co-treated with thiacloprid co-treated with Thiophanate co-treated with Ziram] results in increased expression of CYP2B9 mRNA CTD PMID:32745781 NCBI chr 7:25,872,775...25,910,086
Ensembl chr 7:25,872,836...25,910,086 		JBrowse link
G Cyp2c29 cytochrome P450, family 2, subfamily c, polypeptide 29 multiple interactions EXP [Dietary Fats co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Captan co-treated with Chlorpyrifos co-treated with thiacloprid co-treated with Thiophanate co-treated with Ziram] results in increased expression of CYP2C29 mRNA CTD PMID:32745781 NCBI chr19:39,275,541...39,319,157
Ensembl chr19:39,257,849...39,319,157 		JBrowse link
G Cyp2c38 cytochrome P450, family 2, subfamily c, polypeptide 38 increases expression
decreases expression		 ISO thiacloprid results in increased expression of CYP2C19 mRNA
thiacloprid results in decreased expression of CYP2C19 protein		 CTD PMID:32194361 PMID:32201337 NCBI chr19:39,379,109...39,451,519
Ensembl chr19:39,378,000...39,451,519 		JBrowse link
G Cyp2c55 cytochrome P450, family 2, subfamily c, polypeptide 55 multiple interactions EXP [Ziram co-treated with Thiophanate co-treated with Captan co-treated with Chlorpyrifos co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with thiacloprid] results in increased expression of CYP2C55 mRNA CTD PMID:32736067 NCBI chr19:38,995,384...39,031,134
Ensembl chr19:38,995,463...39,031,137 		JBrowse link
G Cyp2c65 cytochrome P450, family 2, subfamily c, polypeptide 65 increases expression
multiple interactions		 ISO thiacloprid results in increased expression of CYP2C9 protein
[clothianidin co-treated with thiacloprid] results in increased expression of CYP2C9 protein		 CTD PMID:32201337 NCBI chr19:39,049,450...39,082,392
Ensembl chr19:39,049,459...39,082,388 		JBrowse link
G Cyp2e1 cytochrome P450, family 2, subfamily e, polypeptide 1 multiple interactions
decreases expression		 ISO [clothianidin co-treated with thiacloprid] results in increased expression of CYP2E1 protein; [enilconazole co-treated with thiacloprid co-treated with clothianidin] results in decreased expression of CYP2E1 mRNA; [thiacloprid co-treated with clothianidin] results in decreased expression of CYP2E1 mRNA; [thiacloprid co-treated with enilconazole] results in decreased expression of CYP2E1 mRNA
thiacloprid results in decreased expression of CYP2E1 mRNA		 CTD PMID:32201337 NCBI chr 7:140,343,732...140,354,903
Ensembl chr 7:140,343,652...140,354,900 		JBrowse link
G Cyp3a11 cytochrome P450, family 3, subfamily a, polypeptide 11 multiple interactions EXP [Ziram co-treated with Thiophanate co-treated with Captan co-treated with Chlorpyrifos co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with thiacloprid] results in increased expression of CYP3A11 mRNA CTD PMID:32736067 NCBI chr 5:145,791,417...145,816,664
Ensembl chr 5:145,791,236...145,816,774 		JBrowse link
G Cyp3a13 cytochrome P450, family 3, subfamily a, polypeptide 13 increases expression
multiple interactions		 ISO thiacloprid results in increased expression of CYP3A7; thiacloprid results in increased expression of CYP3A7 mRNA
Estriol inhibits the reaction [thiacloprid results in increased expression of CYP3A7]
[enilconazole co-treated with thiacloprid] results in increased expression of CYP3A5 protein; [thiacloprid co-treated with clothianidin] results in increased expression of CYP3A5 mRNA
thiacloprid results in increased expression of CYP3A5 mRNA		 CTD PMID:28750898 PMID:32201337 NCBI chr 5:137,891,195...137,923,872
Ensembl chr 5:137,891,194...137,919,881 		JBrowse link
G Cyp4a10 cytochrome P450, family 4, subfamily a, polypeptide 10 multiple interactions EXP [Ziram co-treated with Thiophanate co-treated with Captan co-treated with Chlorpyrifos co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with thiacloprid] results in increased expression of CYP4A10 mRNA CTD PMID:32736067 NCBI chr 4:115,375,484...115,390,846
Ensembl chr 4:115,375,461...115,390,846 		JBrowse link
G Cyp4a14 cytochrome P450, family 4, subfamily a, polypeptide 14 multiple interactions EXP [Dietary Fats co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Captan co-treated with Chlorpyrifos co-treated with thiacloprid co-treated with Thiophanate co-treated with Ziram] results in increased expression of CYP4A14 mRNA; [Ziram co-treated with Thiophanate co-treated with Captan co-treated with Chlorpyrifos co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with thiacloprid] results in increased expression of CYP4A14 mRNA CTD PMID:32736067 PMID:32745781 NCBI chr 4:115,343,397...115,353,355
Ensembl chr 4:115,343,397...115,353,339 		JBrowse link
G Cyp7a1 cytochrome P450, family 7, subfamily a, polypeptide 1 decreases expression
multiple interactions		 ISO thiacloprid results in decreased expression of CYP7A1 protein
[thiacloprid co-treated with clothianidin] results in decreased expression of CYP7A1 mRNA; [thiacloprid co-treated with enilconazole] results in decreased expression of CYP7A1 mRNA
thiacloprid results in decreased expression of CYP7A1 mRNA		 CTD PMID:32194361 PMID:33426623 NCBI chr 4:6,265,612...6,275,632
Ensembl chr 4:6,265,612...6,275,633 		JBrowse link
G Ddx4 DEAD box helicase 4 decreases expression EXP thiacloprid results in decreased expression of DDX4 mRNA; thiacloprid results in decreased expression of DDX4 protein CTD PMID:37468076 NCBI chr13:112,734,867...112,790,342
Ensembl chr13:112,734,867...112,789,009 		JBrowse link
G Dio1 deiodinase, iodothyronine, type I multiple interactions EXP [Dietary Fats co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Captan co-treated with Chlorpyrifos co-treated with thiacloprid co-treated with Thiophanate co-treated with Ziram] results in increased expression of DIO1 mRNA CTD PMID:32745781 NCBI chr 4:107,148,662...107,164,365
Ensembl chr 4:107,148,662...107,164,366 		JBrowse link
G Eci1 enoyl-Coenzyme A delta isomerase 1 multiple interactions EXP [Ziram co-treated with Thiophanate co-treated with Captan co-treated with Chlorpyrifos co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with thiacloprid] results in increased expression of ECI1 mRNA CTD PMID:32736067 NCBI chr17:24,645,657...24,658,290
Ensembl chr17:24,645,615...24,658,322 		JBrowse link
G Eln elastin multiple interactions
decreases expression		 ISO [thiacloprid co-treated with clothianidin] results in decreased expression of ELN mRNA; [thiacloprid co-treated with enilconazole] results in decreased expression of ELN mRNA
thiacloprid results in decreased expression of ELN mRNA		 CTD PMID:33426623 NCBI chr 5:134,731,449...134,776,300
Ensembl chr 5:134,731,447...134,776,177 		JBrowse link
G Gfap glial fibrillary acidic protein multiple interactions EXP [Ziram co-treated with Thiophanate co-treated with Captan co-treated with Chlorpyrifos co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with thiacloprid] results in increased expression of GFAP protein CTD PMID:32736067 NCBI chr11:102,778,162...102,791,368
Ensembl chr11:102,778,162...102,791,738 		JBrowse link
G Gpt glutamic pyruvic transaminase, soluble increases expression
multiple interactions		 ISO thiacloprid results in increased expression of GPT protein
astaxanthine inhibits the reaction [thiacloprid results in increased expression of GPT protein]; Polysaccharides inhibits the reaction [thiacloprid results in increased expression of GPT protein]		 CTD PMID:31328355 PMID:34564187 NCBI chr15:76,580,926...76,583,875
Ensembl chr15:76,579,916...76,583,886 		JBrowse link
G Gpx1 glutathione peroxidase 1 decreases expression
multiple interactions		 ISO thiacloprid results in decreased expression of GPX1 mRNA
Polysaccharides inhibits the reaction [thiacloprid results in decreased expression of GPX1 mRNA]		 CTD PMID:28692354 NCBI chr 9:108,216,279...108,217,541
Ensembl chr 9:108,216,102...108,217,542 		JBrowse link
G Hmgb1 high mobility group box 1 increases expression
multiple interactions		 ISO thiacloprid results in increased expression of HMGB1 mRNA
astaxanthine inhibits the reaction [thiacloprid results in increased expression of HMGB1 mRNA]		 CTD PMID:34564187 NCBI chr 5:148,983,512...148,989,867
Ensembl chr 5:148,983,512...149,121,299 		JBrowse link
G Hmgcs2 3-hydroxy-3-methylglutaryl-Coenzyme A synthase 2 multiple interactions EXP [Dietary Fats co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Captan co-treated with Chlorpyrifos co-treated with thiacloprid co-treated with Thiophanate co-treated with Ziram] results in increased expression of HMGCS2 mRNA CTD PMID:32745781 NCBI chr 3:98,187,747...98,218,054
Ensembl chr 3:98,187,751...98,218,054 		JBrowse link
G Il10 interleukin 10 increases expression
multiple interactions		 ISO thiacloprid results in increased expression of IL10 protein
astaxanthine inhibits the reaction [thiacloprid results in increased expression of IL10 protein]		 CTD PMID:34564187 NCBI chr 1:130,947,459...130,952,707
Ensembl chr 1:130,947,582...130,952,711 		JBrowse link
G Il1b interleukin 1 beta increases expression
multiple interactions		 ISO thiacloprid results in increased expression of IL1B protein
astaxanthine inhibits the reaction [thiacloprid results in increased expression of IL1B protein]		 CTD PMID:34564187 NCBI chr 2:129,206,490...129,213,059
Ensembl chr 2:129,206,490...129,213,059 		JBrowse link
G Il6 interleukin 6 increases expression ISO thiacloprid results in increased expression of IL6 protein CTD PMID:34564187 NCBI chr 5:30,218,112...30,224,973
Ensembl chr 5:30,218,112...30,224,979 		JBrowse link
G Ins1 insulin I multiple interactions EXP [Dietary Fats co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Captan co-treated with Chlorpyrifos co-treated with thiacloprid co-treated with Thiophanate co-treated with Ziram] results in increased expression of INS1 protein CTD PMID:32745781 NCBI chr19:52,252,735...52,253,453
Ensembl chr19:52,252,735...52,253,914 		JBrowse link
G Ky kyphoscoliosis peptidase decreases expression
multiple interactions		 ISO thiacloprid results in decreased expression of KY mRNA
[thiacloprid co-treated with clothianidin] results in decreased expression of KY mRNA; [thiacloprid co-treated with enilconazole] results in decreased expression of KY mRNA		 CTD PMID:33426623 NCBI chr 9:102,382,954...102,423,443
Ensembl chr 9:102,382,949...102,423,438 		JBrowse link
G Megf11 multiple EGF-like-domains 11 decreases expression
multiple interactions		 ISO thiacloprid results in decreased expression of MEGF11 mRNA
[thiacloprid co-treated with clothianidin] results in decreased expression of MEGF11 mRNA; [thiacloprid co-treated with enilconazole] results in decreased expression of MEGF11 mRNA		 CTD PMID:33426623 NCBI chr 9:64,291,556...64,618,584
Ensembl chr 9:64,292,908...64,616,487 		JBrowse link
G Mki67 antigen identified by monoclonal antibody Ki 67 decreases expression EXP thiacloprid results in decreased expression of MKI67 mRNA; thiacloprid results in decreased expression of MKI67 protein CTD PMID:37468076 NCBI chr 7:135,291,513...135,318,286
Ensembl chr 7:135,291,513...135,318,090 		JBrowse link
G Mme membrane metallo endopeptidase increases expression
multiple interactions		 ISO thiacloprid results in increased expression of MME mRNA
[thiacloprid co-treated with clothianidin] results in increased expression of MME mRNA; [thiacloprid co-treated with enilconazole] results in increased expression of MME mRNA		 CTD PMID:33426623 NCBI chr 3:63,202,632...63,291,134
Ensembl chr 3:63,148,958...63,293,451 		JBrowse link
G Nos2 nitric oxide synthase 2, inducible multiple interactions
increases expression		 ISO astaxanthine inhibits the reaction [thiacloprid results in increased expression of NOS2 mRNA] CTD PMID:34564187 NCBI chr11:78,811,613...78,851,052
Ensembl chr11:78,811,613...78,851,080 		JBrowse link
G Nr1i3 nuclear receptor subfamily 1, group I, member 3 multiple interactions EXP NR1I3 protein affects the susceptibility to [2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Captan co-treated with Chlorpyrifos co-treated with Thiophanate co-treated with thiacloprid co-treated with Ziram] CTD PMID:29950287 NCBI chr 1:171,041,503...171,046,414
Ensembl chr 1:171,041,539...171,048,270 		JBrowse link
G Pdgfrb platelet derived growth factor receptor, beta polypeptide multiple interactions EXP [Ziram co-treated with Thiophanate co-treated with Captan co-treated with Chlorpyrifos co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with thiacloprid] results in increased expression of PDGFRB protein CTD PMID:32736067 NCBI chr18:61,178,194...61,218,139
Ensembl chr18:61,178,222...61,218,133 		JBrowse link
G Por cytochrome p450 oxidoreductase increases expression ISO thiacloprid results in increased expression of POR mRNA CTD PMID:32201337 NCBI chr 5:135,698,894...135,764,180
Ensembl chr 5:135,698,887...135,764,180 		JBrowse link
G Serpine1 serine (or cysteine) peptidase inhibitor, clade E, member 1 multiple interactions EXP [Dietary Fats co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Captan co-treated with Chlorpyrifos co-treated with thiacloprid co-treated with Thiophanate co-treated with Ziram] results in increased expression of SERPINE1 mRNA CTD PMID:32745781 NCBI chr 5:137,090,358...137,101,126
Ensembl chr 5:137,090,358...137,101,122 		JBrowse link
G Slc16a2 solute carrier family 16 (monocarboxylic acid transporters), member 2 multiple interactions EXP [Dietary Fats co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Captan co-treated with Chlorpyrifos co-treated with thiacloprid co-treated with Thiophanate co-treated with Ziram] results in increased expression of SLC16A2 mRNA CTD PMID:32745781 NCBI chr  X:102,741,020...102,865,594
Ensembl chr  X:102,741,020...102,865,589 		JBrowse link
G Slc22a1 solute carrier family 22 (organic cation transporter), member 1 increases activity ISO thiacloprid metabolite results in increased activity of SLC22A1 protein; thiacloprid results in increased activity of SLC22A1 protein CTD PMID:31364238 NCBI chr17:12,867,761...12,894,725
Ensembl chr17:12,867,756...12,894,716 		JBrowse link
G Slc22a2 solute carrier family 22 (organic cation transporter), member 2 decreases activity ISO thiacloprid metabolite results in decreased activity of SLC22A2 protein; thiacloprid results in decreased activity of SLC22A2 protein CTD PMID:31364238 NCBI chr17:12,803,076...12,847,376
Ensembl chr17:12,803,019...12,847,375 		JBrowse link
G Slc22a8 solute carrier family 22 (organic anion transporter), member 8 decreases activity ISO thiacloprid metabolite results in decreased activity of SLC22A8 protein; thiacloprid results in decreased activity of SLC22A8 protein CTD PMID:31364238 NCBI chr19:8,568,576...8,589,199
Ensembl chr19:8,568,618...8,589,199 		JBrowse link
G Slc6a1 solute carrier family 6 (neurotransmitter transporter, GABA), member 1 multiple interactions
decreases expression		 ISO [thiacloprid co-treated with clothianidin] results in decreased expression of SLC6A1 mRNA; [thiacloprid co-treated with enilconazole] results in decreased expression of SLC6A1 mRNA
thiacloprid results in decreased expression of SLC6A1 mRNA		 CTD PMID:33426623 NCBI chr 6:114,259,735...114,294,491
Ensembl chr 6:114,259,596...114,294,493 		JBrowse link
G Sod1 superoxide dismutase 1, soluble decreases expression
multiple interactions		 ISO thiacloprid results in decreased expression of SOD1 mRNA
Polysaccharides inhibits the reaction [thiacloprid results in decreased expression of SOD1 mRNA]		 CTD PMID:28692354 NCBI chr16:90,017,650...90,023,221
Ensembl chr16:90,017,642...90,023,217 		JBrowse link
G Star steroidogenic acute regulatory protein decreases expression EXP thiacloprid results in decreased expression of STAR mRNA CTD PMID:37468076 NCBI chr 8:26,298,502...26,306,010
Ensembl chr 8:26,296,583...26,306,010 		JBrowse link
G Sult1b1 sulfotransferase family 1B, member 1 multiple interactions EXP [Dietary Fats co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Captan co-treated with Chlorpyrifos co-treated with thiacloprid co-treated with Thiophanate co-treated with Ziram] results in increased expression of SULT1B1 mRNA CTD PMID:32745781 NCBI chr 5:87,661,186...87,686,054
Ensembl chr 5:87,661,198...87,686,054 		JBrowse link
G Sycp3 synaptonemal complex protein 3 decreases expression EXP thiacloprid results in decreased expression of SYCP3 mRNA; thiacloprid results in decreased expression of SYCP3 protein CTD PMID:37468076 NCBI chr10:88,295,449...88,309,098
Ensembl chr10:88,295,431...88,309,098 		JBrowse link
G Thrsp thyroid hormone responsive multiple interactions EXP [2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Captan co-treated with Chlorpyrifos co-treated with thiacloprid co-treated with Thiophanate co-treated with Ziram] results in increased expression of THRSP mRNA; [Dietary Fats co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Captan co-treated with Chlorpyrifos co-treated with thiacloprid co-treated with Thiophanate co-treated with Ziram] results in decreased expression of THRSP mRNA; Dietary Fats inhibits the reaction [[2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Captan co-treated with Chlorpyrifos co-treated with thiacloprid co-treated with Thiophanate co-treated with Ziram] results in increased expression of THRSP mRNA] CTD PMID:32745781 NCBI chr 7:97,062,140...97,066,757
Ensembl chr 7:97,062,145...97,066,937 		JBrowse link
G Ugt2b5 UDP glucuronosyltransferase 2 family, polypeptide B5 multiple interactions EXP [Dietary Fats co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Captan co-treated with Chlorpyrifos co-treated with thiacloprid co-treated with Thiophanate co-treated with Ziram] results in increased expression of UGT2B5 mRNA CTD PMID:32745781 NCBI chr 5:87,272,805...87,288,199
Ensembl chr 5:87,272,819...87,288,177 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 22178
    role 22194
      biological role 22162
        xenobiotic 19695
          thiacloprid 65
            (Z)-thiacloprid 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 22178
    subatomic particle 22170
      composite particle 22170
        hadron 22201
          baryon 22170
            nucleon 22170
              atomic nucleus 22170
                atom 22170
                  main group element atom 22104
                    p-block element atom 22104
                      carbon group element atom 21904
                        carbon atom 21859
                          organic molecular entity 21830
                            organic molecule 21647
                              organic cyclic compound 21252
                                organic heterocyclic compound 20352
                                  organic heteromonocyclic compound 18733
                                    pyridines 11798
                                      chloropyridine 5926
                                        monochloropyridine 483
                                          2-chloropyridine 482
                                            thiacloprid 65
                                              (Z)-thiacloprid 0
paths to the root