CHEBI ONTOLOGY - ANNOTATIONS
The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/ . The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/ ). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term: nitenpyram
Accession: CHEBI:39171
browse the term
Definition: A C-nitro compound consisting of 2-nitroethene-1,1-diamine where one of the nitrogens bears ethyl and (6-chloro-3-pyridinyl)methyl while the other nitrogen carries a methyl group.
Synonyms: exact_synonym: N-[(6-chloropyridin-3-yl)methyl]-N-ethyl-N'-methyl-2-nitroethene-1,1-diamine
related_synonym: Formula=C11H15ClN4O2; InChI=1S/C11H15ClN4O2/c1-3-15(11(13-2)8-16(17)18)7-9-4-5-10(12)14-6-9/h4-6,8,13H,3,7H2,1-2H3; InChIKey=CFRPSFYHXJZSBI-UHFFFAOYSA-N; SMILES=[H]C(=C(NC)N(CC)Cc1ccc(Cl)nc1)[N+]([O-])=O
xref: Beilstein:8553513
xref_mesh: MESH:C464843
xref: PMID:10789501; PMID:21714058; Reaxys:8553513
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Akt2
AKT serine/threonine kinase 2
decreases expression
ISO
nitenpyram results in decreased expression of AKT2 mRNA
CTD
PMID:35568224
NCBI chr 1:82,877,228...82,933,828
Ensembl chr 1:82,883,547...82,933,817
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Akt3
AKT serine/threonine kinase 3
decreases expression
ISO
nitenpyram results in decreased expression of AKT3 mRNA
CTD
PMID:35568224
NCBI chr13:88,943,708...89,225,831
Ensembl chr13:88,946,091...89,225,708
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Atm
ATM serine/threonine kinase
increases expression
ISO
nitenpyram results in increased expression of ATM mRNA
CTD
PMID:35568224
NCBI chr 8:53,828,741...53,932,773
Ensembl chr 8:53,831,093...53,932,437
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Atr
ATR serine/threonine kinase
decreases expression
ISO
nitenpyram results in decreased expression of ATR mRNA
CTD
PMID:35568224
NCBI chr 8:96,426,704...96,524,152
Ensembl chr 8:96,426,724...96,524,136
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Bax
BCL2 associated X, apoptosis regulator
increases expression
ISO
nitenpyram results in increased expression of BAX mRNA
CTD
PMID:35568224
NCBI chr 1:95,940,001...95,945,407
Ensembl chr 1:95,938,808...95,945,368
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Cd36
CD36 molecule
increases expression
ISO
nitenpyram results in increased expression of CD36 mRNA
CTD
PMID:35568224
NCBI chr 4:17,317,343...17,410,084
Ensembl chr 4:17,354,466...17,513,903
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Cdkn1a
cyclin-dependent kinase inhibitor 1A
increases expression
ISO
nitenpyram results in increased expression of CDKN1A mRNA
CTD
PMID:35568224
NCBI chr20:7,149,177...7,159,727
Ensembl chr20:7,149,217...7,159,585
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Chrnb2
cholinergic receptor nicotinic beta 2 subunit
multiple interactions
EXP
nitenpyram results in increased activity of [NACHRALPHA1 protein co-treated with CHRNB2 protein]
CTD
PMID:16981889
NCBI chr 2:175,181,402...175,189,619
Ensembl chr 2:175,181,402...175,189,619
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Egf
epidermal growth factor
decreases expression
ISO
nitenpyram results in decreased expression of EGF mRNA
CTD
PMID:35568224
NCBI chr 2:218,219,408...218,302,359
Ensembl chr 2:218,219,415...218,302,064
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Gadd45a
growth arrest and DNA-damage-inducible, alpha
decreases expression
ISO
nitenpyram results in decreased expression of GADD45A mRNA
CTD
PMID:35568224
NCBI chr 4:96,154,789...96,157,091
Ensembl chr 4:96,154,789...96,157,115
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H2ax
H2A.X variant histone
increases expression
ISO
nitenpyram results in increased expression of H2AX mRNA
CTD
PMID:35568224
NCBI chr 8:44,671,907...44,673,262
Ensembl chr 8:44,671,786...44,673,239
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Mdm2
MDM2 proto-oncogene
increases expression
ISO
nitenpyram results in increased expression of MDM2 mRNA
CTD
PMID:35568224
NCBI chr 7:53,290,660...53,315,205
Ensembl chr 7:53,290,664...53,314,915
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Slc22a1
solute carrier family 22 member 1
increases activity
ISO
nitenpyram results in increased activity of SLC22A1 protein
CTD
PMID:31364238
NCBI chr 1:48,076,657...48,103,679
Ensembl chr 1:48,076,666...48,103,678
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Slc22a2
solute carrier family 22 member 2
decreases activity
ISO
nitenpyram results in decreased activity of SLC22A2 protein
CTD
PMID:31364238
NCBI chr 1:48,121,061...48,163,268
Ensembl chr 1:48,121,061...48,163,268
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Slco2b1
solute carrier organic anion transporter family, member 2b1
increases activity
ISO
nitenpyram results in increased activity of SLCO2B1 protein
CTD
PMID:31364238
NCBI chr 1:153,959,288...154,007,294
Ensembl chr 1:153,959,293...154,007,353
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Tp53
tumor protein p53
increases expression
ISO
nitenpyram results in increased expression of TP53 mRNA
CTD
PMID:35568224
NCBI chr10:54,300,070...54,311,525
Ensembl chr10:54,300,048...54,311,524
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