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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:acetamiprid
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Accession:CHEBI:39163 term browser browse the term
Definition:A carboxamidine that is acetamidine in which the amino hydrogens are substituted by a (6-chloropyridin-3-yl)methyl and a methyl group while the hydrogen attached to the imino nitrogen is replaced by a cyano group.
Synonyms:exact_synonym: N-[(6-chloropyridin-3-yl)methyl]-N'-cyano-N-methylethanimidamide
 related_synonym: Formula=C10H11ClN4;   InChI=1S/C10H11ClN4/c1-8(14-7-12)15(2)6-9-3-4-10(11)13-5-9/h3-5H,6H2,1-2H3;   InChIKey=WCXDHFDTOYPNIE-UHFFFAOYSA-N;   N-((6-chloro-3-pyridinyl)methyl)-N'-cyano-N-methylethanimidamide;   SMILES=CN(Cc1ccc(Cl)nc1)C(C)=NC#N
 xref: Beilstein:8546705;   CAS:160430-64-8
 xref_mesh: MESH:C464485
 xref: PMID:24620941;   PMID:24840877;   PMID:25373182;   Reaxys:8546705


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acetamiprid term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Actrt2 actin-related protein T2 decreases expression EXP acetamiprid results in decreased expression of ACTRT2 mRNA CTD PMID:27782041 NCBI chr 5:165,236,092...165,237,492
Ensembl chr 5:165,236,086...165,237,629 		JBrowse link
G Asap2 ArfGAP with SH3 domain, ankyrin repeat and PH domain 2 increases expression EXP acetamiprid results in increased expression of ASAP2 mRNA CTD PMID:27782041 NCBI chr 6:40,658,201...40,821,017
Ensembl chr 6:40,657,880...40,820,975 		JBrowse link
G B3gnt9 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 9 increases expression EXP acetamiprid results in increased expression of B3GNT9 mRNA CTD PMID:27782041 NCBI chr19:33,129,740...33,134,048
Ensembl chr19:33,128,142...33,132,344 		JBrowse link
G Cacna1h calcium voltage-gated channel subunit alpha1 H increases expression EXP acetamiprid results in increased expression of CACNA1H mRNA CTD PMID:27782041 NCBI chr10:14,390,104...14,448,204
Ensembl chr10:14,390,113...14,448,376 		JBrowse link
G Cacng1 calcium voltage-gated channel auxiliary subunit gamma 1 decreases expression EXP acetamiprid results in decreased expression of CACNG1 mRNA CTD PMID:27782041 NCBI chr10:92,652,924...92,665,612
Ensembl chr10:92,652,614...92,665,783 		JBrowse link
G Card11 caspase recruitment domain family, member 11 increases expression EXP acetamiprid results in increased expression of CARD11 mRNA CTD PMID:27782041 NCBI chr12:13,620,979...13,758,115
Ensembl chr12:13,621,087...13,758,112 		JBrowse link
G Cat catalase decreases activity ISO acetamiprid results in decreased activity of CAT protein CTD PMID:31935421 NCBI chr 3:89,842,393...89,874,577
Ensembl chr 3:89,842,399...89,874,478 		JBrowse link
G Chrna4 cholinergic receptor nicotinic alpha 4 subunit decreases expression ISO acetamiprid results in decreased expression of CHRNA4 mRNA CTD PMID:30103633 NCBI chr 3:168,136,246...168,157,839
Ensembl chr 3:168,136,266...168,156,957 		JBrowse link
G Chrna7 cholinergic receptor nicotinic alpha 7 subunit decreases expression ISO acetamiprid results in decreased expression of CHRNA7 mRNA CTD PMID:30103633 NCBI chr 1:116,715,286...116,837,223
Ensembl chr 1:116,714,711...116,837,240 		JBrowse link
G Chrnb2 cholinergic receptor nicotinic beta 2 subunit decreases expression
multiple interactions		 ISO
EXP		 acetamiprid results in decreased expression of CHRNB2
acetamiprid results in increased activity of [NACHRA1 protein co-treated with CHRNB2 protein]; acetamiprid results in increased activity of [NACHRA8 protein co-treated with CHRNB2 protein]		 CTD PMID:16981889 PMID:25459289 PMID:27669271 NCBI chr 2:175,181,402...175,189,619
Ensembl chr 2:175,181,402...175,189,619 		JBrowse link
G Cyp11a1 cytochrome P450, family 11, subfamily a, polypeptide 1 multiple interactions
decreases expression		 EXP
ISO		 Vitamin E inhibits the reaction [acetamiprid results in decreased expression of CYP11A mRNA]; Vitamin E inhibits the reaction [acetamiprid results in decreased expression of CYP11A protein]
acetamiprid results in decreased expression of CYP11A1 mRNA
acetamiprid results in decreased expression of CYP11A1 mRNA; acetamiprid results in decreased expression of CYP11A1 protein		 CTD PMID:28395332 PMID:30103633 NCBI chr 8:58,422,807...58,434,342
Ensembl chr 8:58,404,669...58,434,338 		JBrowse link
G Cyp17a1 cytochrome P450, family 17, subfamily a, polypeptide 1 decreases expression ISO acetamiprid results in decreased expression of CYP17A1 mRNA CTD PMID:30103633 NCBI chr 1:245,535,462...245,543,148
Ensembl chr 1:245,535,462...245,541,573 		JBrowse link
G Dcdc2 doublecortin domain containing 2 increases expression
decreases expression		 EXP acetamiprid results in increased expression of DCDC2 mRNA
acetamiprid results in decreased expression of DCDC2 mRNA		 CTD PMID:27782041 NCBI chr17:39,845,952...40,031,781
Ensembl chr17:39,845,952...40,030,743 		JBrowse link
G Des desmin decreases expression EXP acetamiprid results in decreased expression of DES mRNA CTD PMID:27782041 NCBI chr 9:76,850,979...76,858,695
Ensembl chr 9:76,850,982...76,858,699 		JBrowse link
G F2rl2 coagulation factor II (thrombin) receptor-like 2 increases expression EXP acetamiprid results in increased expression of F2RL2 mRNA CTD PMID:27782041 NCBI chr 2:26,972,054...26,977,098
Ensembl chr 2:26,972,054...26,977,098 		JBrowse link
G Hsd17b1 hydroxysteroid (17-beta) dehydrogenase 1 decreases expression ISO acetamiprid results in decreased expression of HSD17B1 mRNA CTD PMID:30103633 NCBI chr10:86,009,728...86,011,928
Ensembl chr10:86,009,728...86,011,927 		JBrowse link
G Hspb7 heat shock protein family B (small) member 7 decreases expression EXP acetamiprid results in decreased expression of HSPB7 mRNA CTD PMID:27782041 NCBI chr 5:153,727,782...153,731,268
Ensembl chr 5:153,727,588...153,731,266 		JBrowse link
G Iqcf1 IQ motif containing F1 decreases expression EXP acetamiprid results in decreased expression of IQCF1 mRNA CTD PMID:27782041 NCBI chr 8:107,129,462...107,133,242
Ensembl chr 8:107,130,704...107,133,249 		JBrowse link
G Lhb luteinizing hormone subunit beta multiple interactions
increases expression		 EXP Vitamin E inhibits the reaction [acetamiprid results in increased expression of LHB protein] CTD PMID:28395332 NCBI chr 1:95,898,269...95,901,973
Ensembl chr 1:95,900,984...95,901,972
Ensembl chr 1:95,900,984...95,901,972 		JBrowse link
G Lhcgr luteinizing hormone/choriogonadotropin receptor decreases expression ISO acetamiprid results in decreased expression of LHR mRNA CTD PMID:30103633 NCBI chr 6:5,661,871...5,728,109
Ensembl chr 6:5,661,871...5,724,521 		JBrowse link
G Lmod2 leiomodin 2 decreases expression EXP acetamiprid results in decreased expression of LMOD2 mRNA CTD PMID:27782041 NCBI chr 4:53,067,428...53,075,124
Ensembl chr 4:53,067,428...53,075,120 		JBrowse link
G Mb myoglobin decreases expression EXP acetamiprid results in decreased expression of MB mRNA CTD PMID:27782041 NCBI chr 7:108,759,903...108,767,134
Ensembl chr 7:108,759,904...108,767,383 		JBrowse link
G Mcmdc2 minichromosome maintenance domain containing 2 increases expression EXP acetamiprid results in increased expression of MCMDC2 mRNA CTD PMID:27782041 NCBI chr 5:9,291,967...9,337,526
Ensembl chr 5:9,298,101...9,338,300 		JBrowse link
G Mki67 marker of proliferation Ki-67 decreases expression ISO acetamiprid results in decreased expression of MKI67 mRNA CTD PMID:30103633 NCBI chr 1:190,496,319...190,522,983
Ensembl chr 1:190,496,319...190,522,762 		JBrowse link
G Myog myogenin decreases expression EXP acetamiprid results in decreased expression of MYOG mRNA CTD PMID:27782041 NCBI chr13:45,745,455...45,748,044
Ensembl chr13:45,745,436...45,748,039 		JBrowse link
G Nags N-acetylglutamate synthase decreases expression EXP acetamiprid results in decreased expression of NAGS mRNA CTD PMID:27782041 NCBI chr10:87,098,330...87,102,465
Ensembl chr10:87,098,330...87,102,465 		JBrowse link
G Napb NSF attachment protein beta increases expression EXP acetamiprid results in increased expression of NAPB mRNA CTD PMID:27782041 NCBI chr 3:136,132,248...136,179,225
Ensembl chr 3:136,133,428...136,179,345 		JBrowse link
G Ndufaf2 NADH:ubiquinone oxidoreductase complex assembly factor 2 decreases expression EXP acetamiprid results in decreased expression of NDUFAF2 mRNA CTD PMID:27782041 NCBI chr 2:39,535,680...39,647,378
Ensembl chr 2:39,535,689...39,647,316 		JBrowse link
G Olr825 olfactory receptor 825 decreases expression EXP acetamiprid results in decreased expression of OLR825 mRNA CTD PMID:27782041 NCBI chr 4:149,673,586...149,674,569
Ensembl chr 4:149,669,618...149,678,130 		JBrowse link
G Olr94 olfactory receptor 94 decreases expression EXP acetamiprid results in decreased expression of OLR94 mRNA CTD PMID:27782041 NCBI chr 1:157,748,451...157,749,422
Ensembl chr 1:157,748,451...157,749,422 		JBrowse link
G Phf21b PHD finger protein 21B increases expression EXP acetamiprid results in increased expression of PHF21B mRNA CTD PMID:27782041 NCBI chr 7:115,913,704...115,984,215
Ensembl chr 7:115,915,412...115,984,215 		JBrowse link
G Plac8 placenta associated 8 increases expression EXP acetamiprid results in increased expression of PLAC8 mRNA CTD PMID:27782041 NCBI chr14:9,052,601...9,074,264
Ensembl chr14:9,063,048...9,074,264 		JBrowse link
G Slc22a1 solute carrier family 22 member 1 increases activity ISO acetamiprid results in increased activity of SLC22A1 protein CTD PMID:31364238 NCBI chr 1:48,076,657...48,103,679
Ensembl chr 1:48,076,666...48,103,678 		JBrowse link
G Slc22a2 solute carrier family 22 member 2 decreases activity ISO acetamiprid results in decreased activity of SLC22A2 protein CTD PMID:31364238 NCBI chr 1:48,121,061...48,163,268
Ensembl chr 1:48,121,061...48,163,268 		JBrowse link
G Slc22a8 solute carrier family 22 member 8 decreases activity ISO acetamiprid results in decreased activity of SLC22A8 protein CTD PMID:31364238 NCBI chr 1:205,496,331...205,516,378
Ensembl chr 1:205,498,084...205,517,450 		JBrowse link
G Slc45a3 solute carrier family 45, member 3 increases expression EXP acetamiprid results in increased expression of SLC45A3 mRNA CTD PMID:27782041 NCBI chr13:43,407,293...43,427,588
Ensembl chr13:43,407,293...43,427,588 		JBrowse link
G Slco1b2 solute carrier organic anion transporter family member 1B2 decreases expression EXP acetamiprid results in decreased expression of SLCO1B2 mRNA CTD PMID:27782041 NCBI chr 4:174,551,463...174,619,988
Ensembl chr 4:174,551,480...174,619,981 		JBrowse link
G Star steroidogenic acute regulatory protein decreases expression
multiple interactions		 EXP
ISO		 acetamiprid results in decreased expression of STAR mRNA; acetamiprid results in decreased expression of STAR protein
Vitamin E inhibits the reaction [acetamiprid results in decreased expression of STAR mRNA]; Vitamin E inhibits the reaction [acetamiprid results in decreased expression of STAR protein]		 CTD PMID:28395332 PMID:30103633 NCBI chr16:66,267,094...66,274,368
Ensembl chr16:66,264,807...66,271,672 		JBrowse link
G Tada2b transcriptional adaptor 2B increases expression EXP acetamiprid results in increased expression of TADA2B mRNA CTD PMID:27782041 NCBI chr14:74,279,286...74,290,758
Ensembl chr14:74,279,217...74,290,755 		JBrowse link
G Tnni2 troponin I2, fast skeletal type decreases expression EXP acetamiprid results in decreased expression of TNNI2 mRNA CTD PMID:27782041 NCBI chr 1:197,595,012...197,597,554
Ensembl chr 1:197,594,813...197,597,560 		JBrowse link
G Top2a DNA topoisomerase II alpha decreases expression ISO acetamiprid results in decreased expression of TOP2A mRNA CTD PMID:30103633 NCBI chr10:83,946,186...83,975,694
Ensembl chr10:83,945,735...83,976,874 		JBrowse link
G Unc45b unc-45 myosin chaperone B decreases expression EXP acetamiprid results in decreased expression of UNC45B mRNA CTD PMID:27782041 NCBI chr10:67,845,382...67,873,389
Ensembl chr10:67,845,462...67,873,389 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19800
    role 19751
      biological role 19751
        xenobiotic 18436
          acetamiprid 42
            (E)-acetamiprid 0
            (Z)-acetamiprid 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 19800
    subatomic particle 19799
      composite particle 19799
        hadron 19799
          baryon 19799
            nucleon 19799
              atomic nucleus 19799
                atom 19799
                  main group element atom 19698
                    p-block element atom 19698
                      carbon group element atom 19619
                        carbon atom 19609
                          organic molecular entity 19609
                            organic molecule 19549
                              organic cyclic compound 19343
                                organic heterocyclic compound 18584
                                  organic heteromonocyclic compound 17120
                                    pyridines 9156
                                      chloropyridine 2094
                                        monochloropyridine 438
                                          2-chloropyridine 438
                                            acetamiprid 42
                                              (E)-acetamiprid 0
                                              (Z)-acetamiprid 0
paths to the root